David Dawson, M.D., Ph.D.

A Short Biography:

David Dawson is a cell and molecular biologist and practicing surgical pathologist who has served on the UCLA School of Medicine faculty since 2006 when he was appointed Assistant Professor in the Department of Pathology and Laboratory Medicine. Dr. Dawson earned his B.S. in Zoology at Duke University. He earned his M.D. and Ph.D. in Molecular Biology and Genetics at Northwestern University, where he worked on angiogenesis. Dr. Dawson completed his residency training in Anatomic Pathology and subspecialty fellowship in gastrointestinal pathology in the Department of Pathology at UCLA. From 2002 to 2006 he was a combined clinical instructor in surgical pathology and postdoctoral research fellow in the Department of Pathology at UCLA, where he worked on epigenetics and lymphomagenesis. Dr. Dawson's research currently involves basic and translational research on pancreatic tumorigenesis (http://dawsonlab.dgsom.ucla.edu).

Work Titles
UCLA Associate Director, UCLA-Caltech Medical Scientist Training Program Associate Professor, Pathology and Laboratory Medicine Faculty, Cellular and Molecular Pathology PhD Program
Education:
Degrees:
M.D., Northwestern University Dental School, 1999
Ph.D., Northwestern University, 1997
Fellowship:
2001 - 2002 UCLA School of Medicine
Internship:
1999 - 2000 UCLA School of Medicine
Residency:
2000 - 2001 UCLA School of Medicine
Certifications:
Certifications:
2002 American Board of Pathology

Contact Information:

Lab Number:

310 825-0618

Office Phone Number:

(310) 267-2799

Laboratory Address:

Lab Address
Factor 8-240


Mailing Address:

Mailing Address
Dept. of Pathology
Mail Code 173216
10833 LeConte Avenue
Los Angeles, CA 90095


Office Address:

Office
Factor 8-240J
Los Angeles, CA 90095


Detailed Biography:

David Dawson is a cell and molecular biologist and practicing surgical pathologist who has served on the UCLA School of Medicine faculty since 2006 when he was appointed Assistant Professor in the Department of Pathology and Laboratory Medicine. Dr. Dawson earned his B.S. in Zoology at Duke University. He earned his M.D. and Ph.D. in Molecular Biology and Genetics at Northwestern University, where he worked on angiogenesis. Dr. Dawson completed his residency training in Anatomic Pathology and subspecialty fellowship in gastrointestinal pathology in the Department of Pathology at UCLA. From 2002 to 2006 he was a combined clinical instructor in surgical pathology and postdoctoral research fellow in the Department of Pathology at UCLA, where he worked on epigenetics and lymphomagenesis. Dr. Dawson's research currently involves basic and translational research on pancreatic tumorigenesis.

Publications:

Arensman, M. D.; Telesca, D.; Lay, A. R.; Kershaw, K. M.; Wu, N.; Donahue, T. R.; Dawson, D. W.   The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth Mol Cancer Ther, 2014; 13(10): 2303-14.
von Figura, G.; Fukuda, A.; Roy, N.; Liku, M. E.; Morris Iv, J. P.; Kim, G. E.; Russ, H. A.; Firpo, M. A.; Mulvihill, S. J.; Dawson, D. W.; Ferrer, J.; Mueller, W. F.; Busch, A.; Hertel, K. J.; Hebrok, M.   The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma Nat Cell Biol, 2014; 16(3): 255-67.
Farrell, J. J.; Toste, P.; Wu, N.; Li, L.; Wong, J.; Malkhassian, D.; Tran, L. M.; Wu, X.; Li, X.; Dawson, D.; Wu, H.; Donahue, T. R.   Endoscopically acquired pancreatic cyst fluid microRNA 21 and 221 are associated with invasive cancer Am J Gastroenterol, 2013; 108(8): 1352-9.
Dawson, D. W.; Hertzer, K.; Moro, A.; Donald, G.; Chang, H. H.; Go, V. L.; Pandol, S. J.; Lugea, A.; Gukovskaya, A. S.; Li, G.; Hines, O. J.; Rozengurt, E.; Eibl, G.   High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model Cancer Prev Res (Phila), 2013; 6(10): 1064-73.
Butler, A. E.; Campbell-Thompson, M.; Gurlo, T.; Dawson, D. W.; Atkinson, M.; Butler, P. C.   Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors Diabetes, 2013; 62(7): 2595-604.
Kadera, B. E.; Li, L.; Toste, P. A.; Wu, N.; Adams, C.; Dawson, D. W.; Donahue, T. R.   MicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasis PLoS One, 2013; 8(8): e71978.
Toste, P. A.; Kadera, B. E.; Tatishchev, S. F.; Dawson, D. W.; Clerkin, B. M.; Muthusamy, R.; Watson, R.; Tomlinson, J. S.; Hines, O. J.; Reber, H. A.; Donahue, T. R.   Nonfunctional pancreatic neuroendocrine tumors <2 cm on preoperative imaging are associated with a low incidence of nodal metastasis and an excellent overall survival J Gastrointest Surg, 2013; 17(12): 2105-13.
Khachatoorian, R.; Dawson, D.; Maloney, E. M.; Wang, J.; French, B. A.; French, S. W.   SAMe treatment prevents the ethanol-induced epigenetic alterations of genes in the Toll-like receptor pathway Exp Mol Pathol, 2013; 94(1): 243-6.
White, B. D.; Chien, A. J.; Dawson, D. W.   Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers Gastroenterology, 2012; 142(2): 219-32.
Pandol, S.; Gukovskaya, A.; Edderkaoui, M.; Dawson, D.; Eibl, G.; Lugea, A.   Epidemiology, risk factors, and the promotion of pancreatic cancer: role of the stellate cell J Gastroenterol Hepatol, 2012; 27 Suppl 2: 127-34.
Takahashi, H.; Li, A.; Dawson, D. W.; Hines, O. J.; Reber, H. A.; Eibl, G.   Cyclooxygenase-2 confers growth advantage to syngeneic pancreatic cancer cells Pancreas, 2011; 40(3): 453-9.
Angst, E.; Dawson, D. W.; Stroka, D.; Gloor, B.; Park, J.; Candinas, D.; Reber, H. A.; Hines, O. J.; Eibl, G.   N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo Surgery, 2011; 149(5): 614-24.
Li, A.; King, J.; Moro, A.; Sugi, M. D.; Dawson, D. W.; Kaplan, J.; Li, G.; Lu, X.; Strieter, R. M.; Burdick, M.; Go, V. L.; Reber, H. A.; Eibl, G.; Hines, O. J.   Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer Am J Pathol, 2011; 178(3): 1340-9.
Lucero, O. M.; Dawson, D. W.; Moon, R. T.; Chien, A. J.   A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers Curr Oncol Rep, 2010; 12(5): 314-8.
Angst, E.; Dawson, D. W.; Nguyen, A.; Park, J.; Go, V. L.; Reber, H. A.; Hines, O. J.; Eibl, G.   Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells Pancreas, 2010; 39(5): 675-9.
Pham, H.; Chen, M.; Li, A.; King, J.; Angst, E.; Dawson, D. W.; Park, J.; Reber, H. A.; Hines, O. J.; Eibl, G.   Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors Pancreas, 2010; 39(3): 332-9.
Balatoni, C. E.; Dawson, D. W.; Suh, J.; Sherman, M. H.; Sanders, G.; Hong, J. S.; Frank, M. J.; Malone, C. S.; Said, J. W.; Teitell, M. A.   Epigenetic silencing of Stk39 in B-cell lymphoma inhibits apoptosis from genotoxic stress Am J Pathol, 2009; 175(4): 1653-61.
Tang, R. S.; Weinberg, B.; Dawson, D. W.; Reber, H.; Hines, O. J.; Tomlinson, J. S.; Chaudhari, V.; Raman, S.; Farrell, J. J.   Evaluation of the guidelines for management of pancreatic branch-duct intraductal papillary mucinous neoplasm Clin Gastroenterol Hepatol, 2008; 6(7): 815-9; quiz 719.
Hasan, S.; Satake, M.; Dawson, D. W.; Funahashi, H.; Angst, E.; Go, V. L.; Reber, H. A.; Hines, O. J.; Eibl, G.   Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers Pancreas, 2008; 37(2): 121-7.
Thomas, R. M.; Kim, J.; Revelo-Penafiel, M. P.; Angel, R.; Dawson, D. W.; Lowy, A. M.   The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia Gut, 2008; 57(11): 1555-60.
Pelling, A. E.; Dawson, D. W.; Carreon, D. M.; Christiansen, J. J.; Shen, R. R.; Teitell, M. A.; Gimzewski, J. K.   Distinct contributions of microtubule subtypes to cell membrane shape and stability Nanomedicine, 2007; 3(1): 43-52.
Chen, H. W.; Rainey, R. N.; Balatoni, C. E.; Dawson, D. W.; Troke, J. J.; Wasiak, S.; Hong, J. S.; McBride, H. M.; Koehler, C. M.; Teitell, M. A.; French, S. W.   Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis Mol Cell Biol, 2006; 26(22): 8475-87.
Goodarzi, M. O.; Dawson, D. W.; Li, X.; Lei, Z.; Shintaku, P.; Rao, C. V.; Van Herle, A. J.   Virilization in bilateral macronodular adrenal hyperplasia controlled by luteinizing hormone J Clin Endocrinol Metab, 2003; 88(1): 73-7.
French, S. W.; Dawson, D. W.; Miner, M. D.; Doerr, J. R.; Malone, C. S.; Wall, R.; Teitell, M. A.   DNA methylation profiling: a new tool for evaluating hematologic malignancies Clin Immunol, 2002; 103(3 Pt 1): 217-30.
Dawson, D. W.; Volpert, O. V.; Pearce, S. F.; Schneider, A. J.; Silverstein, R. L.; Henkin, J.; Bouck, N. P.   Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat Mol Pharmacol, 1999; 55(2): 332-8.
Dawson David W, Fernandez-Zapico Martin E   Gemcitabine Activates Natural Killer Cells to Attenuate Pancreatic Cancer Recurrence Gastroenterology, 2016; 151(2): 234-7.
Donahue Timothy R, Dawson David W   Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality Trends in endocrinology and metabolism: TEM, 2016; 151(2): .
Stark Alexander P, Sacks Greg D, Rochefort Matthew M, Donahue Timothy R, Reber Howard A, Tomlinson James S, Dawson David W, Eibl Guido, Hines O Joe   Long-term survival in patients with pancreatic ductal adenocarcinoma Surgery, 2016; 159(6): 1520-7.
Toste Paul A, Nguyen Andrew H, Kadera Brian E, Duong Mindy, Wu Nanping, Gawlas Irmina, Tran Linh M, Bikhchandani Mihir, Li Luyi, Patel Sanjeet G, Dawson David W, Donahue Timothy R   Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK Molecular cancer research : MCR, 2016; 14(5): 437-47.
Principe Daniel R, DeCant Brian, Mascariñas Emman, Wayne Elizabeth A, Diaz Andrew M, Akagi Naomi, Hwang Rosa, Pasche Boris, Dawson David W, Fang Deyu, Bentrem David J, Munshi Hidayatullah G, Jung Barbara, Grippo Paul J   TGFβ Signaling in the Pancreatic Tumor Microenvironment Promotes Fibrosis and Immune Evasion to Facilitate Tumorigenesis Cancer research, 2016; 76(9): 2525-39.
Moris Maria, Dawson David W, Jiang Jennifer, Lewis Jason, Nassar Aziza, Takeuchi Kenneth K, Lay Anna R, Zhai Qihui, Donahue Timothy R, Kelly Kimberly A, Crawford Howard C, Wallace Michael   Plectin-1 as a Biomarker of Malignant Progression in Intraductal Papillary Mucinous Neoplasms: A Multicenter Study Pancreas, 2016; 14(5): .
Hertzer Kathleen M, Xu Mu, Moro Aune, Dawson David W, Du Lin, Li Gang, Chang Hui-Hua, Stark Alexander P, Jung Xiaoman, Hines Oscar Joe, Eibl Guido   Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer Pancreas, 2016; 45(3): 458-65.
Arensman Michael D, Nguyen Phillip, Kershaw Kathleen M, Lay Anna R, Ostertag-Hill Claire A, Sherman Mara H, Downes Michael, Liddle Christopher, Evans Ronald M, Dawson David W   Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer Molecular cancer research : MCR, 2015; 13(11): 1509-19.
Mareninova Olga A, Sendler Matthias, Malla Sudarshan Ravi, Yakubov Iskandar, French Samuel W, Tokhtaeva Elmira, Vagin Olga, Oorschot Viola, Lüllmann-Rauch Renate, Blanz Judith, Dawson David, Klumperman Judith, Lerch Markus M, Mayerle Julia, Gukovsky Ilya, Gukovskaya Anna S   Lysosome associated membrane proteins maintain pancreatic acinar cell homeostasis: LAMP-2 deficient mice develop pancreatitis Cellular and molecular gastroenterology and hepatology, 2015; 1(6): 678-694.
Williams Jennifer L, Nguyen Andrew H, Rochefort Matthew, Muthusamy V Raman, Wainberg Zev A, Dawson David W, Tomlinson James S, Hines O Joe, Reber Howard A, Donahue Timothy R   Pancreatic cancer patients with lymph node involvement by direct tumor extension have similar survival to those with node-negative disease Journal of surgical oncology, 2015; 112(4): 396-402.
Toste Paul A, Li Luyi, Kadera Brian E, Nguyen Andrew H, Tran Linh M, Wu Nanping, Madnick David L, Patel Sanjeet G, Dawson David W, Donahue Timothy R   p85α is a microRNA target and affects chemosensitivity in pancreatic cancer The Journal of surgical research, 2015; 196(2): 285-93.
Roy Nilotpal, Malik Shivani, Villanueva Karina E, Urano Atsushi, Lu Xinyuan, Von Figura Guido, Seeley E Scott, Dawson David W, Collisson Eric A, Hebrok Matthias   Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation Genes & development, 2015; 29(6): 658-71.
Thompson Michael J, Rubbi Liudmilla, Dawson David W, Donahue Timothy R, Pellegrini Matteo   Pancreatic cancer patient survival correlates with DNA methylation of pancreas development genes PloS one, 2015; 10(6): e0128814.
Chen Ru, Dawson David W, Pan Sheng, Ottenhof Niki A, de Wilde Roeland F, Wolfgang Christopher L, May Damon H, Crispin David A, Lai Lisa A, Lay Anna R, Waghray Meghna, Wang Shouli, McIntosh Martin W, Simeone Diane M, Maitra Anirban, Brentnall Teresa A   Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma Laboratory investigation; a journal of technical methods and pathology, 2015; 95(1): 43-55.
Liou, G. Y.; Doppler, H.; Necela, B.; Edenfield, B.; Zhang, L.; Dawson, D. W.; Storz, P.   Mutant Kras-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions Cancer Discov, 2014; .
Kadera, B. E.; Toste, P. A.; Wu, N.; Li, L.; Nguyen, A. H.; Dawson, D. W.; Donahue, T. R.   Low Expression of the E3 Ubiquitin Ligase CBL Confers Chemoresistance in Human Pancreatic Cancer and Is Targeted by Epidermal Growth Factor Receptor Inhibition Clin Cancer Res, 2014; .
Chen, R.; Dawson, D. W.; Pan, S.; Ottenhof, N. A.; de Wilde, R. F.; Wolfgang, C. L.; May, D. H.; Crispin, D. A.; Lai, L. A.; Lay, A. R.; Waghray, M.; Wang, S.; McIntosh, M. W.; Simeone, D. M.; Maitra, A.; Brentnall, T. A.   Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma Lab Invest, 2014; .
Nguyen David, Dawson David W, Hines O Joe, Reber Howard A, Donahue Timothy R   Mucinous cystic neoplasms of the pancreas: are we overestimating malignant potential? The American surgeon, 2014; 80(10): 915-9.
Sherman, M. H.; Yu, R. T.; Engle, D. D.; Ding, N.; Atkins, A. R.; Tiriac, H.; Collisson, E. A.; Connor, F.; Van Dyke, T.; Kozlov, S.; Martin, P.; Tseng, T. W.; Dawson, D. W.; Donahue, T. R.; Masamune, A.; Shimosegawa, T.; Apte, M. V.; Wilson, J. S.; Ng, B.; Lau, S. L.; Gunton, J. E.; Wahl, G. M.; Hunter, T.; Drebin, J. A.; O'Dwyer, P. J.; Liddle, C.; Tuveson, D. A.; Downes, M.; Evans, R. M.   Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy Cell, 2014; 159(1): 80-93.
Kadera Brian E, Sunjaya Dharma B, Isacoff William H, Li Luyi, Hines O Joe, Tomlinson James S, Dawson David W, Rochefort Matthew M, Donald Graham W, Clerkin Barbara M, Reber Howard A, Donahue Timothy R   Locally advanced pancreatic cancer: association between prolonged preoperative treatment and lymph-node negativity and overall survival JAMA surgery, 2014; 149(2): 145-53.
Farrell, J. J.; Toste, P.; Wu, N.; Li, L.; Wong, J.; Malkhassian, D.; Tran, L. M.; Wu, X.; Li, X.; Dawson, D.; Wu, H.; Donahue, T. R.   Endoscopically Acquired Pancreatic Cyst Fluid MicroRNA 21 and 221 Are Associated With Invasive Cancer Am J Gastroenterol, 2013; .
Li, N.; Wu, X.; Holzer, R. G.; Lee, J. H.; Todoric, J.; Park, E. J.; Ogata, H.; Gukovskaya, A. S.; Gukovsky, I.; Pizzo, D. P.; VandenBerg, S.; Tarin, D.; Atay, C.; Arkan, M. C.; Deerinck, T. J.; Moscat, J.; Diaz-Meco, M.; Dawson, D.; Erkan, M.; Kleeff, J.; Karin, M.   Loss of acinar cell IKKalpha triggers spontaneous pancreatitis in mice J Clin Invest, 2013; 123(5): 2231-43.
Arensman, M. D.; Kovochich, A. N.; Kulikauskas, R. M.; Lay, A. R.; Yang, P. T.; Li, X.; Donahue, T.; Major, M. B.; Moon, R. T.; Chien, A. J.; Dawson, D. W.   WNT7B mediates autocrine Wnt/beta-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma Oncogene, 2013; .
Nguyen Kovochich, A.; Arensman, M.; Lay, A. R.; Rao, N. P.; Donahue, T.; Li, X.; French, S. W.; Dawson, D. W.   HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma Cancer, 2013; 119(3): 529-39.
Mann, K. M.; Ward, J. M.; Yew, C. C.; Kovochich, A.; Dawson, D. W.; Black, M. A.; Brett, B. T.; Sheetz, T. E.; Dupuy, A. J.; Chang, D. K.; Biankin, A. V.; Waddell, N.; Kassahn, K. S.; Grimmond, S. M.; Rust, A. G.; Adams, D. J.; Jenkins, N. A.; Copeland, N. G.   Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma Proc Natl Acad Sci U S A, 2012; 109(16): 5934-41.
Donahue, T. R.; Tran, L. M.; Hill, R.; Li, Y.; Kovochich, A.; Calvopina, J. H.; Patel, S. G.; Wu, N.; Hindoyan, A.; Farrell, J. J.; Li, X.; Dawson, D. W.; Wu, H.   Integrative survival-based molecular profiling of human pancreatic cancer Clin Cancer Res, 2012; 18(5): 1352-63.
Camp, N. D.; James, R. G.; Dawson, D. W.; Yan, F.; Davison, J. M.; Houck, S. A.; Tang, X.; Zheng, N.; Major, M. B.; Moon, R. T.   Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein J Biol Chem, 2012; 287(9): 6539-50.
White Bryan D, Chien Andy J, Dawson David W   Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers Gastroenterology, 2012; 142(2): 219-32.
Biechele, T. L.; Kulikauskas, R. M.; Toroni, R. A.; Lucero, O. M.; Swift, R. D.; James, R. G.; Robin, N. C.; Dawson, D. W.; Moon, R. T.; Chien, A. J.   Wnt/beta-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma Sci Signal, 2012; 5(206): ra3.
Donahue, T. R.; Dawson, D. W.   Nodal/Activin signaling: a novel target for pancreatic cancer stem cell therapy Cell Stem Cell, 2011; 9(5): 383-4.
Hill, R.; Calvopina, J. H.; Kim, C.; Wang, Y.; Dawson, D. W.; Donahue, T. R.; Dry, S.; Wu, H.   PTEN loss accelerates KrasG12D-induced pancreatic cancer development Cancer Res, 2010; 70(18): 7114-24.
Zhang, L.; Angst, E.; Park, J. L.; Moro, A.; Dawson, D. W.; Reber, H. A.; Eibl, G.; Hines, O. J.; Go, V. L.; Lu, Q. Y.   Quercetin aglycone is bioavailable in murine pancreas and pancreatic xenografts J Agric Food Chem, 2010; 58(12): 7252-7.
Manuyakorn, A.; Paulus, R.; Farrell, J.; Dawson, N. A.; Tze, S.; Cheung-Lau, G.; Hines, O. J.; Reber, H.; Seligson, D. B.; Horvath, S.; Kurdistani, S. K.; Guha, C.; Dawson, D. W.   Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704 J Clin Oncol, 2010; 28(8): 1358-65.
Chen, S. S.; Raval, A.; Johnson, A. J.; Hertlein, E.; Liu, T. H.; Jin, V. X.; Sherman, M. H.; Liu, S. J.; Dawson, D. W.; Williams, K. E.; Lanasa, M.; Liyanarachchi, S.; Lin, T. S.; Marcucci, G.; Pekarsky, Y.; Davuluri, R.; Croce, C. M.; Guttridge, D. C.; Teitell, M. A.; Byrd, J. C.; Plass, C.   Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia Proc Natl Acad Sci U S A, 2009; 106(32): 13433-8.
Frank, M. J.; Dawson, D. W.; Bensinger, S. J.; Hong, J. S.; Knosp, W. M.; Xu, L.; Balatoni, C. E.; Allen, E. L.; Shen, R. R.; Bar-Sagi, D.; Martin, G. R.; Teitell, M. A.   Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas Blood, 2009; 113(11): 2478-87.
Smiraglia, D. J.; Kazhiyur-Mannar, R.; Oakes, C. C.; Wu, Y. Z.; Liang, P.; Ansari, T.; Su, J.; Rush, L. J.; Smith, L. T.; Yu, L.; Liu, C.; Dai, Z.; Chen, S. S.; Wang, S. H.; Costello, J.; Ioshikhes, I.; Dawson, D. W.; Hong, J. S.; Teitell, M. A.; Szafranek, A.; Camoriano, M.; Song, F.; Elliott, R.; Held, W.; Trasler, J. M.; Plass, C.; Wenger, R.   Restriction Landmark Genomic Scanning (RLGS) spot identification by second generation virtual RLGS in multiple genomes with multiple enzyme combinations BMC Genomics, 2007; 8(1): 446.
Funahashi, H.; Satake, M.; Dawson, D.; Huynh, N. A.; Reber, H. A.; Hines, O. J.; Eibl, G.   Delayed progression of pancreatic intraepithelial neoplasia in a conditional Kras(G12D) mouse model by a selective cyclooxygenase-2 inhibitor Cancer Res, 2007; 67(15): 7068-71.
Dawson, D. W.; Hong, J. S.; Shen, R. R.; French, S. W.; Troke, J. J.; Wu, Y. Z.; Chen, S. S.; Gui, D.; Regelson, M.; Marahrens, Y.; Morse, H. C., 3rd; Said, J.; Plass, C.; Teitell, M. A.   Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas Oncogene, 2007; 26(29): 4243-52.
French, S. W.; Dawson, D. W.; Chen, H. W.; Rainey, R. N.; Sievers, S. A.; Balatoni, C. E.; Wong, L.; Troke, J. J.; Nguyen, M. T.; Koehler, C. M.; Teitell, M. A.   The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity Cancer Lett, 2007; 248(2): 198-210.
Ouyang, Y.; Salstrom, J.; Diaz-Perez, S.; Nahas, S.; Matsuno, Y.; Dawson, D.; Teitell, M. A.; Horvath, S.; Riggs, A. D.; Gatti, R. A.; Marahrens, Y.   Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome Biochem Biophys Res Commun, 2005; 337(3): 875-80.
Hoyer, K. K.; Herling, M.; Bagrintseva, K.; Dawson, D. W.; French, S. W.; Renard, M.; Weinger, J. G.; Jones, D.; Teitell, M. A.   T cell leukemia-1 modulates TCR signal strength and IFN-gamma levels through phosphatidylinositol 3-kinase and protein kinase C pathway activation J Immunol, 2005; 175(2): 864-73.
Dawson, D. W.; Volpert, O. V.; Gillis, P.; Crawford, S. E.; Xu, H.; Benedict, W.; Bouck, N. P.   Pigment epithelium-derived factor: a potent inhibitor of angiogenesis Science, 1999; 285(5425): 245-8.
Dawson, D. W.; Pearce, S. F.; Zhong, R.; Silverstein, R. L.; Frazier, W. A.; Bouck, N. P.   CD36 mediates the In vitro inhibitory effects of thrombospondin-1 on endothelial cells J Cell Biol, 1997; 138(3): 707-17.

Does this profile need updating? Contact Us