Irina Kramerova


Work Titles
UCLA Associate Researcher, David Geffen School of Medicine at UCLA

Contact Information:

Work Phone Number:

310-267-4582

Mailing Address:

NRB1 #404
Los Angeles, CA 90095


Publications:

A selected list of publications:

DiFranco Marino, Kramerova Irina, Vergara Julio L, Spencer Melissa Jan   Attenuated Ca(2+) release in a mouse model of limb girdle muscular dystrophy 2A Skeletal muscle, 2016; 6: 11.
Kramerova Irina, Ermolova Natalia, Eskin Ascia, Hevener Andrea, Quehenberger Oswald, Armando Aaron M, Haller Ronald, Romain Nadine, Nelson Stanley F, Spencer Melissa J   Failure to up-regulate transcription of genes necessary for muscle adaptation underlies limb girdle muscular dystrophy 2A (calpainopathy) Human molecular genetics, 2016; 25(11): 2194-2207.
Kramerova I, Kudryashova E, Ermolova N, Saenz A, Jaka O, L√≥pez de Munain A, Spencer M J   Impaired calcium calmodulin kinase signaling and muscle adaptation response in the absence of calpain 3 Human molecular genetics, 2012; 21(14): 3193-204.
Kudryashova Elena, Kramerova Irina, Spencer Melissa J   Satellite cell senescence underlies myopathy in a mouse model of limb-girdle muscular dystrophy 2H The Journal of clinical investigation, 2012; 122(5): 1764-76.
Ermolova Natalia, Kudryashova Elena, DiFranco Marino, Vergara Julio, Kramerova Irina, Spencer Melissa J   Pathogenity of some limb girdle muscular dystrophy mutations can result from reduced anchorage to myofibrils and altered stability of calpain 3 Human molecular genetics, 2011; 20(17): 3331-45.
Kramerova Irina, Kudryashova Elena, Wu Benjamin, Germain Sean, Vandenborne Krista, Romain Nadine, Haller Ronald G, Verity M Anthony, Spencer Melissa J   Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle Human molecular genetics, 2009; 18(17): 3194-205.
Kramerova Irina, Kudryashova Elena, Wu Benjamin, Ottenheijm Coen, Granzier Henk, Spencer Melissa J   Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle Human molecular genetics, 2008; 17(21): 3271-80.
Kramerova Irina, Beckmann Jacques S, Spencer Melissa J   Molecular and cellular basis of calpainopathy (limb girdle muscular dystrophy type 2A) Biochimica et biophysica acta, 2007; 1772(2): 128-44.
Kramerova Irina, Kudryashova Elena, Venkatraman Gayathri, Spencer Melissa J   Calpain 3 participates in sarcomere remodeling by acting upstream of the ubiquitin-proteasome pathway Human molecular genetics, 2005; 14(15): 2125-34.
Kramerova I, Kudryashova E, Tidball J G, Spencer Melissa J   Null mutation of calpain 3 (p94) in mice causes abnormal sarcomere formation in vivo and in vitro Human molecular genetics, 2004; 13(13): 1373-88.

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