Martin G Martin

Title(s)Professor, Pediatrics
SchoolMedicine
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    COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepository
    NIH RC2DK118640Sep 15, 2019 - Jun 30, 2024
    Role: Principal Investigator
    Smooth Muscle Cell-Based Assesment and Therapy for Myopathic forms of CIPO
    NIH R21DK111216Jun 1, 2017 - May 31, 2021
    Role: Principal Investigator
    Intestinal Stem Cell Culture and Entero-Endocrine Lineage Development
    NIH U01DK085535Sep 30, 2009 - Aug 31, 2020
    Role: Principal Investigator
    Neurogenin3 and Intestinal Failure
    NIH R01DK083762Jul 1, 2009 - Jun 30, 2015
    Role: Principal Investigator
    Cell Fate Determination of the Intestine and Chronic Diarrhea in Children
    NIH R21DK075009May 15, 2006 - Apr 30, 2009
    Role: Principal Investigator
    Regulation of Intestinal Nutrient Transporters
    NIH R03HD041034Sep 24, 2001 - Jun 30, 2004
    Role: Principal Investigator
    MOLECULAR BASIS OF ENTEROCYTE REGULATION DURING ONTOGENY
    NIH R01HD034706Mar 1, 1998 - Feb 28, 2004
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake. Science. 2023 11 10; 382(6671):eadf0966. Ferrari A, Whang E, Xiao X, Kennelly JP, Romartinez-Alonso B, Mack JJ, Weston T, Chen K, Kim Y, Tol MJ, Bideyan L, Nguyen A, Gao Y, Cui L, Bedard AH, Sandhu J, Lee SD, Fairall L, Williams KJ, Song W, Munguia P, Russell RA, Martin MG, Jung ME, Jiang H, Schwabe JWR, Young SG, Tontonoz P. PMID: 37943936.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Statins inhibit protein kinase D (PKD) activation in intestinal cells and prevent PKD1-induced growth of murine enteroids. Am J Physiol Cell Physiol. 2023 04 01; 324(4):C807-C820. Sinnett-Smith J, Torres-Marquez ME, Chang JK, Shimizu Y, Hao F, Martin MG, Rozengurt E. PMID: 36779664; PMCID: PMC10042602.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. An Unusual Case of Infantile Hepatic Steatosis Caused by Coconut-Based Infant Formula. JPGN Rep. 2022 Nov; 3(4):e235. Prieto Jimenez PM, Jun-Ihn E, Matthews M, Lollie T, Qu Y, Martin MG. PMID: 37168470; PMCID: PMC10158368.
      View in: PubMed   Mentions:
    4. The Diverse Phenotype of Intestinal Dysmotility Secondary to ACTG2-related Disorders. J Pediatr Gastroenterol Nutr. 2022 05 01; 74(5):575-581. Sandy NS, Huysentruyt K, Mulder DJ, Warner N, Chong K, Morel C, AlQahtani S, Wales PW, Martin MG, Muise AM, Avitzur Y. PMID: 35149643; PMCID: PMC9632465.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    5. The G209R mutant mouse as a model for human PCSK1 polyendocrinopathy. Endocrinology. 2022 Mar 04. Shakya M, Gahlot S, Martin NK, Arunagiri A, Martin MG, Arvan P, Low MJ, Lindberg I. PMID: 35245347; PMCID: PMC9044177.
      View in: PubMed   Mentions:    Fields:    
    6. Macrophage COX2 Mediates Efferocytosis, Resolution Reprogramming, and Intestinal Epithelial Repair. Cell Mol Gastroenterol Hepatol. 2022; 13(4):1095-1120. Meriwether D, Jones AE, Ashby JW, Solorzano-Vargas RS, Dorreh N, Noori S, Grijalva V, Ball AB, Semis M, Divakaruni AS, Mack JJ, Herschman HR, Martin MG, Fogelman AM, Reddy ST. PMID: 35017061; PMCID: PMC8873959.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    7. The Molecular Basis of Glucose Galactose Malabsorption in a Large Swedish Pedigree. Function (Oxf). 2021; 2(5):zqab040. Lostao MP, Loo DD, Hernell O, Meeuwisse G, Martin MG, Wright EM. PMID: 34485913; PMCID: PMC8410129.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    8. Expansion of NEUROD2 phenotypes to include developmental delay without seizures. Am J Med Genet A. 2021 04; 185(4):1076-1080. Mis EK, Sega AG, Signer RH, Cartwright T, Ji W, Martinez-Agosto JA, Nelson SF, Palmer CGS, Lee H, Mitzelfelt T, Konstantino M, Undiagnosed Diseases Network, Jeffries L, Khokha MK, Marco E, Martin MG, Lakhani SA. PMID: 33438828; PMCID: PMC8212414.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    9. Long-Term Dietary Changes in Subjects with Glucose Galactose Malabsorption Secondary to Biallelic Mutations of SLC5A1. Dig Dis Sci. 2021 12; 66(12):4414-4422. Chan AP, Namjoshi SS, Jardack PM, Maloney L, Ardjmand A, Jackson NN, Martin MG. PMID: 33433815; PMCID: PMC8273183.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    10. Intestinal adaptation following spring insertion into a roux limb in mice. J Pediatr Surg. 2021 Feb; 56(2):346-351. Portelli KI, Park JB, Taylor JS, Thomas AL, Stelzner M, Martin MG, Dunn JCY. PMID: 32709529; PMCID: PMC7772252.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    11. Gut-on-a-chip: Current progress and future opportunities. Biomaterials. 2020 10; 255:120196. Ashammakhi N, Nasiri R, Barros NR, Tebon P, Thakor J, Goudie M, Shamloo A, Martin MG, Khademhosseini A. PMID: 32623181; PMCID: PMC7396314.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    12. DNA Methylation Analysis Validates Organoids as a Viable Model for Studying Human Intestinal Aging. Cell Mol Gastroenterol Hepatol. 2020; 9(3):527-541. Lewis SK, Nachun D, Martin MG, Horvath S, Coppola G, Jones DL. PMID: 31805439; PMCID: PMC7044532.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    13. Diagnostic utility of transcriptome sequencing for rare Mendelian diseases. Genet Med. 2020 03; 22(3):490-499. Lee H, Huang AY, Wang LK, Yoon AJ, Renteria G, Eskin A, Signer RH, Dorrani N, Nieves-Rodriguez S, Wan J, Douine ED, Woods JD, Dell'Angelica EC, Fogel BL, Martin MG, Butte MJ, Parker NH, Wang RT, Shieh PB, Wong DA, Gallant N, Singh KE, Tavyev Asher YJ, Sinsheimer JS, Krakow D, Loo SK, Allard P, Papp JC, Undiagnosed Diseases Network, Palmer CGS, Martinez-Agosto JA, Nelson SF. PMID: 31607746; PMCID: PMC7405636.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansCells
    14. Apolipoprotein A-I mimetics mitigate intestinal inflammation in COX2-dependent inflammatory bowel disease model. J Clin Invest. 2019 06 11; 129(9):3670-3685. Meriwether D, Sulaiman D, Volpe C, Dorfman A, Grijalva V, Dorreh N, Solorzano-Vargas RS, Wang J, O'Connor E, Papesh J, Larauche M, Trost H, Palgunachari MN, Anantharamaiah GM, Herschman HR, Martin MG, Fogelman AM, Reddy ST. PMID: 31184596; PMCID: PMC6715371.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    15. Intestinal epithelial replacement by transplantation of cultured murine and human cells into the small intestine. PLoS One. 2019; 14(5):e0216326. Khalil HA, Hong SN, Rouch JD, Scott A, Cho Y, Wang J, Lewis MS, Martin MG, Dunn JCY, Stelzner MG. PMID: 31150401; PMCID: PMC6544206.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    16. Esophageal IgG4: Clinical, Endoscopic, and Histologic Correlations in Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2019 05; 68(5):689-694. Pope AE, Stanzione N, Naini BV, Garcia-Lloret M, Ghassemi KA, Marcus EA, Martin MG, Wozniak LJ. PMID: 30540707; PMCID: PMC8384046.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    17. Introduction to themed series on intestinal stem cells and the NIDDK Intestinal Stem Cell Consortium. Am J Physiol Gastrointest Liver Physiol. 2019 02 01; 316(2):G247-G250. Wang TC, Martin MG, Kuo CJ, Klein OD, Niland J. PMID: 30548077.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    18. EPCAM mutation update: Variants associated with congenital tufting enteropathy and Lynch syndrome. Hum Mutat. 2019 02; 40(2):142-161. Pathak SJ, Mueller JL, Okamoto K, Das B, Hertecant J, Greenhalgh L, Cole T, Pinsk V, Yerushalmi B, Gurkan OE, Yourshaw M, Hernandez E, Oesterreicher S, Naik S, Sanderson IR, Axelsson I, Agardh D, Boland CR, Martin MG, Putnam CD, Sivagnanam M. PMID: 30461124; PMCID: PMC6328345.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    19. Apical Membrane Alterations in Non-intestinal Organs in Microvillus Inclusion Disease. Dig Dis Sci. 2018 02; 63(2):356-365. Schlegel C, Weis VG, Knowles BC, Lapierre LA, Martin MG, Dickman P, Goldenring JR, Shub MD. PMID: 29218485; PMCID: PMC5797493.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    20. Intestinal Enteroendocrine Lineage Cells Possess Homeostatic and Injury-Inducible Stem Cell Activity. Cell Stem Cell. 2017 07 06; 21(1):78-90.e6. Yan KS, Gevaert O, Zheng GXY, Anchang B, Probert CS, Larkin KA, Davies PS, Cheng ZF, Kaddis JS, Han A, Roelf K, Calderon RI, Cynn E, Hu X, Mandleywala K, Wilhelmy J, Grimes SM, Corney DC, Boutet SC, Terry JM, Belgrader P, Ziraldo SB, Mikkelsen TS, Wang F, von Furstenberg RJ, Smith NR, Chandrakesan P, May R, Chrissy MAS, Jain R, Cartwright CA, Niland JC, Hong YK, Carrington J, Breault DT, Epstein J, Houchen CW, Lynch JP, Martin MG, Plevritis SK, Curtis C, Ji HP, Li L, Henning SJ, Wong MH, Kuo CJ. PMID: 28686870; PMCID: PMC5642297.
      View in: PubMed   Mentions: 162     Fields:    Translation:AnimalsCells
    21. Stem Cells and Regeneration in the Digestive System: Keystone Meeting. Gastroenterology. 2016 09; 151(3):e6-9. Soffers JH, Hansen D, Sinagoga KL, Li B, Martin MG, Wells J, Grompe M, Li L. PMID: 27480172; PMCID: PMC6044286.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    22. Pharmacologically blocking p53-dependent apoptosis protects intestinal stem cells and mice from radiation. Sci Rep. 2015 Apr 10; 5:8566. Wang X, Wei L, Cramer JM, Leibowitz BJ, Judge C, Epperly M, Greenberger J, Wang F, Li L, Stelzner MG, Dunn JCY, Martin MG, Lagasse E, Zhang L, Yu J. PMID: 25858503; PMCID: PMC4392360.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    23. From diarrhea to obesity in prohormone convertase 1/3 deficiency: age-dependent clinical, pathologic, and enteroendocrine characteristics. J Clin Gastroenterol. 2013 Nov-Dec; 47(10):834-43. Bandsma RH, Sokollik C, Chami R, Cutz E, Brubaker PL, Hamilton JK, Perlman K, Zlotkin S, Sigalet DL, Sherman PM, Martin MG, Avitzur Y. PMID: 24135795; PMCID: PMC3842618.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    24. Brief report: CD24 and CD44 mark human intestinal epithelial cell populations with characteristics of active and facultative stem cells. Stem Cells. 2013 Sep; 31(9):2024-30. Gracz AD, Fuller MK, Wang F, Li L, Stelzner M, Dunn JC, Martin MG, Magness ST. PMID: 23553902; PMCID: PMC3783577.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansCells
    25. A multicenter study to standardize reporting and analyses of fluorescence-activated cell-sorted murine intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2013 Oct 15; 305(8):G542-51. Magness ST, Puthoff BJ, Crissey MA, Dunn J, Henning SJ, Houchen C, Kaddis JS, Kuo CJ, Li L, Lynch J, Martin MG, May R, Niland JC, Olack B, Qian D, Stelzner M, Swain JR, Wang F, Wang J, Wang X, Yan K, Yu J, Wong MH. PMID: 23928185; PMCID: PMC3798732.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    26. Isolation and characterization of intestinal stem cells based on surface marker combinations and colony-formation assay. Gastroenterology. 2013 Aug; 145(2):383-95.e1-21. Wang F, Scoville D, He XC, Mahe MM, Box A, Perry JM, Smith NR, Lei NY, Davies PS, Fuller MK, Haug JS, McClain M, Gracz AD, Ding S, Stelzner M, Dunn JC, Magness ST, Wong MH, Martin MG, Helmrath M, Li L. PMID: 23644405; PMCID: PMC3781924.
      View in: PubMed   Mentions: 119     Fields:    Translation:HumansAnimalsCells
    27. Congenital proprotein convertase 1/3 deficiency causes malabsorptive diarrhea and other endocrinopathies in a pediatric cohort. Gastroenterology. 2013 Jul; 145(1):138-148. Martín MG, Lindberg I, Solorzano-Vargas RS, Wang J, Avitzur Y, Bandsma R, Sokollik C, Lawrence S, Pickett LA, Chen Z, Egritas O, Dalgic B, Albornoz V, de Ridder L, Hulst J, Gok F, Aydogan A, Al-Hussaini A, Gok DE, Yourshaw M, Wu SV, Cortina G, Stanford S, Georgia S. PMID: 23562752; PMCID: PMC3719133.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    28. Dicer1 is required to repress neuronal fate during endocrine cell maturation. Diabetes. 2013 May; 62(5):1602-11. Kanji MS, Martin MG, Bhushan A. PMID: 23382448; PMCID: PMC3636616.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    29. A nomenclature for intestinal in vitro cultures. Am J Physiol Gastrointest Liver Physiol. 2012 Jun 15; 302(12):G1359-63. Stelzner M, Helmrath M, Dunn JC, Henning SJ, Houchen CW, Kuo C, Lynch J, Li L, Magness ST, Martin MG, Wong MH, Yu J, NIH Intestinal Stem Cell Consortium. PMID: 22461030; PMCID: PMC3378093.
      View in: PubMed   Mentions: 128     Fields:    Translation:HumansCells
    30. Nucleotide sequence of the Na+/H+ exchanger-8 in patients with congenital sodium diarrhea. J Pediatr Gastroenterol Nutr. 2011 Nov; 53(5):474-7. Baum M, Martin MG, Booth IW, Holmberg C, Twombley K, Zhang Q, Gattineni J, Moe O. PMID: 21666503; PMCID: PMC4098726.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    31. Novel anti-inflammatory functions for endothelial and myeloid cyclooxygenase-2 in a new mouse model of Crohn's disease. Am J Physiol Gastrointest Liver Physiol. 2010 Jun; 298(6):G842-50. Watanabe J, Lin JA, Narasimha AJ, Shahbazian A, Ishikawa TO, Martin MG, Herschman HR, Reddy ST. PMID: 20299600; PMCID: PMC8875131.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    32. Atherogenic diet causes lethal ileo-ceco-colitis in cyclooxygenase-2 deficient mice. Prostaglandins Other Lipid Mediat. 2007 Nov; 84(3-4):98-107. Lin JA, Watanabe J, Rozengurt N, Narasimha A, Martin MG, Wang J, Braun J, Langenbach R, Reddy ST. PMID: 17991612; PMCID: PMC2701900.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    33. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr. 2006 May; 148(5):652-658. Squires RH, Shneider BL, Bucuvalas J, Alonso E, Sokol RJ, Narkewicz MR, Dhawan A, Rosenthal P, Rodriguez-Baez N, Murray KF, Horslen S, Martin MG, Lopez MJ, Soriano H, McGuire BM, Jonas MM, Yazigi N, Shepherd RW, Schwarz K, Lobritto S, Thomas DW, Lavine JE, Karpen S, Ng V, Kelly D, Simonds N, Hynan LS. PMID: 16737880; PMCID: PMC2662127.
      View in: PubMed   Mentions: 204     Fields:    Translation:Humans
    34. Varicella in pediatric liver transplant patients: a retrospective analysis of treatment and outcome. J Pediatr Gastroenterol Nutr. 2003 Aug; 37(2):183-6. Pacini-Edelstein SJ, Mehra M, Ament ME, Vargas JH, Martin MG, McDiarmid SV. PMID: 12883306.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    35. The unique occurrence of hepatic failure from type 1 autoimmune hepatitis with concurrent brain abscess. J Pediatr Gastroenterol Nutr. 2003 Mar; 36(3):414-7. Pacini-Edelstein SJ, Bahar RJ, McDiarmid SV, Vargas JH, Martin MG, Mehra M, Ament ME. PMID: 12604986.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Molecular basis for glucose-galactose malabsorption. Cell Biochem Biophys. 2002; 36(2-3):115-21. Wright EM, Turk E, Martin MG. PMID: 12139397.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    37. Regulation of the human Na(+)-glucose cotransporter gene, SGLT1, by HNF-1 and Sp1. Am J Physiol Gastrointest Liver Physiol. 2000 Apr; 278(4):G591-603. Martín MG, Wang J, Solorzano-Vargas RS, Lam JT, Turk E, Wright EM. PMID: 10762614.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells