James Weiss, M.D.


Work Titles
CTSI Member, CTSI Member, Workforce Development
UCLA Director, Cardiovascular Research Laboratory Chief, Cardiology Professor, Medicine Member, Molecular, Cellular & Integrative Physiology GPB Home Area
Education:
Degrees:
M.D., University of Pennsylvania School of Medicine, 1971 - 1975
A.B., Hamilton College, Clinton, NY, 1967 - 1971
Fellowship:
1978 - 1981 UCLA School of Medicine
Internship:
1975 - 1976 Hospital of the University of Pennsylvania
Residency:
1978 - 1981 UCLA School of Medicine, Los Angeles
1975 - 1978 University of Pennsylvania School of Medicine
Certifications:
Certifications:
1981 American Board of Internal Medicine
1978 American Board of Internal Medicine
Certification Type:
1969 - 1970 Edinburg University, Edinburgh, Scotland, UK, Mathematics, Physica and Chemistry

Contact Information:

Work Email Address:

jweiss@mednet.ucla.edu


Website:


Web-Profile 2
Web-Profile

Lab Number:

(310) 825-6713

Office Phone Number:

(310) 825-9029

Work Phone Number:

(310) 825-8811

Laboratory Address:

Laboratory
675 Charles E. Young Dr. South
MRL bldg. 3641
Los Angeles, CA 90095


Mailing Address:

Business
David Geffen School of Medicine at UCLA
675 S. Charles Young Drive
MRL Bldg 3645
Los Angeles, CA 90095


Detailed Biography:

James N. Weiss received his medical degree and internal medicine training at the University of Pennsylvania School of Medicine. He completed his cardiology fellowship training at the UCLA 1981, including clinical electrophysiology training at the University of Maastricht, the Netherlands. He then joined the faculty at the School of Medicine, where he was director of Clinical Cardiac Electrophysiology from 1981-1985, and became a full professor in 1989. He became the Director of the Cardiovascular Research Laboratory and Professor of Physiology in 1996, and Chief of Cardiology in 2001. His research focuses on ion channel biophysics, cardiac electrophysiology, arrhythmias, and ischemia and mitochondrial biology. He leads an interdisciplinary group combining mathematical and experimental biology. He holds memberships in numerous professional organizations, including the American Heart Association, American College of Cardiology, the Heart Rhythm Society, the Biophysical Society, the American Society of Clinical Investigation, the Association of University Cardiologists.

Publications:

Lee Young Soo, Chang Po-Cheng, Hsueh Chia-Hsiang, Maruyama Mitsunori, Park Hyung Wook, Rhee Kyoung-Suk, Hsieh Yu-Cheng, Shen Changyu, Weiss James N, Chen Zhenhui, Lin Shien-Fong, Chen Peng-Sheng   Apamin-Sensitive Calcium-Activated Potassium Currents in Rabbit Ventricles with Chronic Myocardial Infarction Journal of cardiovascular electrophysiology, 2013; .
Hsieh Yu-Cheng, Chang Po-Cheng, Hsueh Chia-Hsiang, Lee Young Soo, Shen Changyu, Weiss James N, Chen Zhenhui, Ai Tomohiko, Lin Shien-Fong, Chen Peng-Sheng   Apamin-sensitive potassium current modulates action potential duration restitution and arrhythmogenesis of failing rabbit ventricles Circulation. Arrhythmia and electrophysiology, 2013; 6(2): 410-8.
Qu Zhilin, Nivala Michael, Weiss James N   Calcium alternans in cardiac myocytes: order from disorder Journal of molecular and cellular cardiology, 2013; 58: 100-9.
Qu Zhilin, Xie Lai-Hua, Olcese Riccardo, Karagueuzian Hrayr S, Chen Peng-Sheng, Garfinkel Alan, Weiss James N   Early Afterdepolarizations in Cardiac Myocytes: Beyond Reduced Repolarization Reserve Cardiovascular research, 2013; 58: .
Rau Christoph D, Wisniewski Nicholas, Orozco Luz D, Bennett Brian, Weiss James, Lusis Aldons J   Maximal information component analysis: a novel non-linear network analysis method Frontiers in genetics, 2013; 4(4): 28.
Youn Ji-Youn, Zhang Jun, Zhang Yixuan, Chen Houzao, Liu Depei, Ping Peipei, Weiss James N, Cai Hua   Oxidative stress in atrial fibrillation: An emerging role of NADPH oxidase Journal of molecular and cellular cardiology, 2013; .
Karagueuzian Hrayr S, Nguyen Thao P, Qu Zhilin, Weiss James N   Oxidative stress, fibrosis, and early afterdepolarization-mediated cardiac arrhythmias Frontiers in physiology, 2013; 4(4): 19.
Chang Marvin G, de Lange Enno, Calmettes Guillaume, Garfinkel Alan, Qu Zhilin, Weiss James N   Pro- and antiarrhythmic effects of ATP-sensitive potassium current activation on reentry during early afterdepolarization-mediated arrhythmias Heart rhythm : the official journal of the Heart Rhythm Society, 2013; 10(4): 575-82.
Weiss James N, Karma Alain, MacLellan W Robb, Deng Mario, Rau Christoph D, Rees Colin M, Wang Jessica, Wisniewski Nicholas, Eskin Eleazar, Horvath Steve, Qu Zhilin, Wang Yibin, Lusis Aldons J   "Good enough solutions" and the genetics of complex diseases Circulation research, 2012; 111(4): 493-504.
Nguyen Thao P, Xie Yuanfang, Garfinkel Alan, Qu Zhilin, Weiss James N   Arrhythmogenic consequences of myofibroblast-myocyte coupling Cardiovascular research, 2012; 93(2): 242-51.
Chang Marvin G, Sato Daisuke, de Lange Enno, Lee Jong-Hwan, Karagueuzian Hrayr S, Garfinkel Alan, Weiss James N, Qu Zhilin   Bi-stable wave propagation and early afterdepolarization-mediated cardiac arrhythmias Heart rhythm : the official journal of the Heart Rhythm Society, 2012; 9(1): 115-22.
Nivala Michael, Ko Christopher Y, Nivala Melissa, Weiss James N, Qu Zhilin   Criticality in intracellular calcium signaling in cardiac myocytes Biophysical journal, 2012; 102(11): 2433-42.
Chang Marvin G, Chang Connie Y, de Lange Enno, Xu Linmiao, O'Rourke Brian, Karagueuzian Hrayr S, Tung Leslie, Marbán Eduardo, Garfinkel Alan, Weiss James N, Qu Zhilin, Abraham M Roselle   Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers Biophysical journal, 2012; 102(12): 2706-14.
Bapat Aneesh, Nguyen Thao P, Lee Jong-Hwan, Sovari Ali A, Fishbein Michael C, Weiss James N, Karagueuzian Hrayr S   Enhanced sensitivity of aged fibrotic hearts to angiotensin II- and hypokalemia-induced early afterdepolarization-mediated ventricular arrhythmias American journal of physiology. Heart and circulatory physiology, 2012; 302(11): H2331-40.
Ghazalpour Anatole, Rau Christoph D, Farber Charles R, Bennett Brian J, Orozco Luz D, van Nas Atila, Pan Calvin, Allayee Hooman, Beaven Simon W, Civelek Mete, Davis Richard C, Drake Thomas A, Friedman Rick A, Furlotte Nick, Hui Simon T, Jentsch J David, Kostem Emrah, Kang Hyun Min, Kang Eun Yong, Joo Jong Wha, Korshunov Vyacheslav A, Laughlin Rick E, Martin Lisa J, Ohmen Jeffrey D, Parks Brian W, Pellegrini Matteo, Reue Karen, Smith Desmond J, Tetradis Sotirios, Wang Jessica, Wang Yibin, Weiss James N, Kirchgessner Todd, Gargalovic Peter S, Eskin Eleazar, Lusis Aldons J, LeBoeuf Renée C   Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits Mammalian genome : official journal of the International Mammalian Genome Society, 2012; 23(9-10): 680-92.
Calaghan Sarah, Steele Derek, Weiss James N   Local signalling in myocytes Journal of molecular and cellular cardiology, 2012; 52(2): 295-7.
Xi Yutao, Ai Tomohiko, De Lange Enno, Li Zhaohui, Wu Geru, Brunelli Luca, Kyle W Buck, Turker Isik, Cheng Jie, Ackerman Michael J, Kimura Akinori, Weiss James N, Qu Zhilin, Kim Jeffrey J, Faulkner Georgine, Vatta Matteo   Loss of function of hNav1.5 by a ZASP1 mutation associated with intraventricular conduction disturbances in left ventricular noncompaction Circulation. Arrhythmia and electrophysiology, 2012; 5(5): 1017-26.
Zhang Jun, Lin Amanda, Powers Jared, Lam Maggie P, Lotz Christopher, Liem David, Lau Edward, Wang Ding, Deng Ning, Korge Paavo, Zong Nobel C, Cai Hua, Weiss James, Ping Peipei   Perspectives on: SGP symposium on mitochondrial physiology and medicine: mitochondrial proteome design: from molecular identity to pathophysiological regulation The Journal of general physiology, 2012; 139(6): 395-406.
Numata Ayaka, Miyauchi Yasushi, Ono Norihiko, Fishbein Michael C, Mandel William J, Lin Shien-Fong, Weiss James N, Chen Peng-Sheng, Karagueuzian Hrayr S   Spontaneous atrial fibrillation initiated by tyramine in canine atria with increased sympathetic nerve sprouting Journal of cardiovascular electrophysiology, 2012; 23(4): 415-22.
Weiss James N, Nivala Michael, Garfinkel Alan, Qu Zhilin   Alternans and arrhythmias: from cell to heart Circulation research, 2011; 108(1): 98-112.
de Diego Carlos, Chen Fuhua, Xie Yuanfang, Pai Rakesh K, Slavin Leonid, Parker John, Lamp Scott T, Qu Zhilin, Weiss James N, Valderrábano Miguel   Anisotropic conduction block and reentry in neonatal rat ventricular myocyte monolayers American journal of physiology. Heart and circulatory physiology, 2011; 300(1): H271-8.
Baher Alex A, Uy Matthew, Xie Fagen, Garfinkel Alan, Qu Zhilin, Weiss James N   Bidirectional ventricular tachycardia: ping pong in the His-Purkinje system Heart rhythm : the official journal of the Heart Rhythm Society, 2011; 8(4): 599-605.
John Scott A, Ribalet Bernard, Weiss James N, Philipson Kenneth D, Ottolia Michela   Ca2+-dependent structural rearrangements within Na+-Ca2+ exchanger dimers Proceedings of the National Academy of Sciences of the United States of America, 2011; 108(4): 1699-704.
Maruyama Mitsunori, Lin Shien-Fong, Xie Yuanfang, Chua Su-Kiat, Joung Boyoung, Han Seongwook, Shinohara Tetsuji, Shen Mark J, Qu Zhilin, Weiss James N, Chen Peng-Sheng   Genesis of phase 3 early afterdepolarizations and triggered activity in acquired long-QT syndrome Circulation. Arrhythmia and electrophysiology, 2011; 4(1): 103-11.
Morita Norishige, Lee Jong-Hwan, Bapat Aneesh, Fishbein Michael C, Mandel William J, Chen Peng-Sheng, Weiss James N, Karagueuzian Hrayr S   Glycolytic inhibition causes spontaneous ventricular fibrillation in aged hearts American journal of physiology. Heart and circulatory physiology, 2011; 301(1): H180-91.
Joung Boyoung, Park Hyung-Wook, Maruyama Mitsunori, Tang Liang, Song Juan, Han Seongwook, Piccirillo Gianfranco, Weiss James N, Lin Shien-Fong, Chen Peng-Sheng   Intracellular calcium and the mechanism of anodal supernormal excitability in langendorff perfused rabbit ventricles Circulation journal : official journal of the Japanese Circulation Society, 2011; 75(4): 834-43.
Nivala Melissa, Korge Paavo, Nivala Michael, Weiss James N, Qu Zhilin   Linking flickering to waves and whole-cell oscillations in a mitochondrial network model Biophysical journal, 2011; 101(9): 2102-11.
Qu Zhilin, Garfinkel Alan, Weiss James N, Nivala Melissa   Multi-scale modeling in biology: how to bridge the gaps between scales? Progress in biophysics and molecular biology, 2011; 107(1): 21-31.
Deng Ning, Zhang Jun, Zong Chenggong, Wang Yueju, Lu Haojie, Yang Pengyuan, Wang Wenhai, Young Glen W, Wang Yibin, Korge Paavo, Lotz Christopher, Doran Philip, Liem David A, Apweiler Rolf, Weiss James N, Duan Huilong, Ping Peipei   Phosphoproteome analysis reveals regulatory sites in major pathways of cardiac mitochondria Molecular & cellular proteomics : MCP, 2011; 10(2): M110.000117.
Korge Paavo, Yang Ling, Yang Jun-Hai, Wang Yibin, Qu Zhilin, Weiss James N   Protective role of transient pore openings in calcium handling by cardiac mitochondria The Journal of biological chemistry, 2011; 286(40): 34851-7.
Sdek Patima, Zhao Peng, Wang Yaping, Huang Chang-Jiang, Ko Christopher Y, Butler Peter C, Weiss James N, Maclellan W Robb   Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes The Journal of cell biology, 2011; 194(3): 407-23.
Madhvani Roshni V, Xie Yuanfang, Pantazis Antonios, Garfinkel Alan, Qu Zhilin, Weiss James N, Olcese Riccardo   Shaping a new Ca²⁺ conductance to suppress early afterdepolarizations in cardiac myocytes The Journal of physiology, 2011; 589(Pt 24): 6081-92.
Chua Su-Kiat, Chang Po-Cheng, Maruyama Mitsunori, Turker Isik, Shinohara Tetsuji, Shen Mark J, Chen Zhenhui, Shen Changyu, Rubart-von der Lohe Michael, Lopshire John C, Ogawa Masahiro, Weiss James N, Lin Shien-Fong, Ai Tomohiko, Chen Peng-Sheng   Small-conductance calcium-activated potassium channel and recurrent ventricular fibrillation in failing rabbit ventricles Circulation research, 2011; 108(8): 971-9.
John Scott, Weiss James N, Ribalet Bernard   Subcellular localization of hexokinases I and II directs the metabolic fate of glucose PloS one, 2011; 6(3): e17674.
Morita Norishige, Lee Jong Hwan, Xie Yuanfang, Sovari Ali, Qu Zhilin, Weiss James N, Karagueuzian Hrayr S   Suppression of re-entrant and multifocal ventricular fibrillation by the late sodium current blocker ranolazine Journal of the American College of Cardiology, 2011; 57(3): 366-75.
Chen Fuhua, De Diego Carlos, Chang Marvin G, McHarg Jennifer L, John Scott, Klitzner Thomas S, Weiss James N   Atrioventricular conduction and arrhythmias at the initiation of beating in embryonic mouse hearts Developmental dynamics : an official publication of the American Association of Anatomists, 2010; 239(7): 1941-9.
Lusis Aldons J, Weiss James N   Cardiovascular networks: systems-based approaches to cardiovascular disease Circulation, 2010; 121(1): 157-70.
Maruyama Mitsunori, Joung Boyoung, Tang Liang, Shinohara Tetsuji, On Young-Keun, Han Seongwook, Choi Eue-Keun, Kim Dae-Hyeok, Shen Mark J, Weiss James N, Lin Shien-Fong, Chen Peng-Sheng   Diastolic intracellular calcium-membrane voltage coupling gain and postshock arrhythmias: role of purkinje fibers and triggered activity Circulation research, 2010; 106(2): 399-408.
Weiss James N, Garfinkel Alan, Karagueuzian Hrayr S, Chen Peng-Sheng, Qu Zhilin   Early afterdepolarizations and cardiac arrhythmias Heart rhythm : the official journal of the Heart Rhythm Society, 2010; 7(12): 1891-9.
Sato Daisuke, Xie Lai-Hua, Nguyen Thao P, Weiss James N, Qu Zhilin   Irregularly appearing early afterdepolarizations in cardiac myocytes: random fluctuations or dynamical chaos? Biophysical journal, 2010; 99(3): 765-73.
Yang Ling, Korge Paavo, Weiss James N, Qu Zhilin   Mitochondrial oscillations and waves in cardiac myocytes: insights from computational models Biophysical journal, 2010; 98(8): 1428-38.
Weiss James N, Yang Jun-Hai   Oscillations at odds in the heart The Journal of general physiology, 2010; 135(4): 303-5.
Xie Yuanfang, Sato Daisuke, Garfinkel Alan, Qu Zhilin, Weiss James N   So little source, so much sink: requirements for afterdepolarizations to propagate in tissue Biophysical journal, 2010; 99(5): 1408-15.
Rovetti Robert, Cui Xiaohua, Garfinkel Alan, Weiss James N, Qu Zhilin   Spark-induced sparks as a mechanism of intracellular calcium alternans in cardiac myocytes Circulation research, 2010; 106(10): 1582-91.
Qu Zhilin, Xie Yuanfang, Garfinkel Alan, Weiss James N   T-wave alternans and arrhythmogenesis in cardiac diseases Frontiers in physiology, 2010; 1(2): 154.
Ji Sen, Gupta Nigel, Weiss James N   The heart and its nerves: a nervous bond Heart rhythm : the official journal of the Heart Rhythm Society, 2010; 7(4): 504-5.
Sato Daisuke, Xie Yuanfang, Weiss James N, Qu Zhilin, Garfinkel Alan, Sanderson Allen R   Acceleration of cardiac tissue simulation with graphic processing units Medical & biological engineering & computing, 2009; 47(9): 1011-5.
Xie Lai-Hua, Weiss James N   Arrhythmogenic consequences of intracellular calcium waves American journal of physiology. Heart and circulatory physiology, 2009; 297(3): H997-H1002.
Tran Diana X, Sato Daisuke, Yochelis Arik, Weiss James N, Garfinkel Alan, Qu Zhilin   Bifurcation and chaos in a model of cardiac early afterdepolarizations Physical review letters, 2009; 102(25): 258103.
Xie Yuanfang, Garfinkel Alan, Weiss James N, Qu Zhilin   Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models American journal of physiology. Heart and circulatory physiology, 2009; 297(2): H775-84.
Xie Yuanfang, Garfinkel Alan, Camelliti Patrizia, Kohl Peter, Weiss James N, Qu Zhilin   Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational study Heart rhythm : the official journal of the Heart Rhythm Society, 2009; 6(11): 1641-9.
Lu Gang, Sun Haipeng, Korge Paavo, Koehler Carla M, Weiss James N, Wang Yibin   Functional characterization of a mitochondrial Ser/Thr protein phosphatase in cell death regulation Methods in enzymology, 2009; 457(6): 255-73.
Morita Norishige, Sovari Ali A, Xie Yuanfang, Fishbein Michael C, Mandel William J, Garfinkel Alan, Lin Shien-Fong, Chen Peng-Sheng, Xie Lai-Hua, Chen Fuhua, Qu Zhilin, Weiss James N, Karagueuzian Hrayr S   Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress American journal of physiology. Heart and circulatory physiology, 2009; 297(5): H1594-605.
Joung Boyoung, Tang Liang, Maruyama Mitsunori, Han Seongwook, Chen Zhenhui, Stucky Marcelle, Jones Larry R, Fishbein Michael C, Weiss James N, Chen Peng-Sheng, Lin Shien-Fong   Intracellular calcium dynamics and acceleration of sinus rhythm by beta-adrenergic stimulation Circulation, 2009; 119(6): 788-96.
Ogawa Masahiro, Morita Norishige, Tang Liang, Karagueuzian Hrayr S, Weiss James N, Lin Shien-Fong, Chen Peng-Sheng   Mechanisms of recurrent ventricular fibrillation in a rabbit model of pacing-induced heart failure Heart rhythm : the official journal of the Heart Rhythm Society, 2009; 6(6): 784-92.
Xie Lai-Hua, Chen Fuhua, Karagueuzian Hrayr S, Weiss James N   Oxidative-stress-induced afterdepolarizations and calmodulin kinase II signaling Circulation research, 2009; 104(1): 79-86.
Cui Xiaohua, Rovetti Robert J, Yang Ling, Garfinkel Alan, Weiss James N, Qu Zhilin   Period-doubling bifurcation in an array of coupled stochastically excitable elements subjected to global periodic forcing Physical review letters, 2009; 103(4): 044102.
Sato Daisuke, Xie Lai-Hua, Sovari Ali A, Tran Diana X, Morita Norishige, Xie Fagen, Karagueuzian Hrayr, Garfinkel Alan, Weiss James N, Qu Zhilin   Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias Proceedings of the National Academy of Sciences of the United States of America, 2009; 106(9): 2983-8.
Mahajan, Aman Shiferaw, Yohannes Sato, Daisuke Baher, Ali Olcese, Riccardo Xie, Lai-Hua Yang, Ming-Jim Chen, Peng-Sheng Restrepo, Juan G. Karma, Alain Garfinkel, Alan Qu, Zhilin Weiss, James N.   A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates Biophys. J, 2008; 94(2): 392-410.
Mahajan Aman, Shiferaw Yohannes, Sato Daisuke, Baher Ali, Olcese Riccardo, Xie Lai-Hua, Yang Ming-Jim, Chen Peng-Sheng, Restrepo Juan G, Karma Alain, Garfinkel Alan, Qu Zhilin, Weiss James N   A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates Biophysical journal, 2008; 94(2): 392-410.
Zhang Jun, Liem David A, Mueller Michael, Wang Yueju, Zong Chenggong, Deng Ning, Vondriska Thomas M, Korge Paavo, Drews Oliver, Maclellan W Robb, Honda Henry, Weiss James N, Apweiler Rolf, Ping Peipei   Altered proteome biology of cardiac mitochondria under stress conditions Journal of proteome research, 2008; 7(6): 2204-14.
Weiss James N   Beyond the implantable cardioverter-defibrillator: are we making progress? Heart rhythm : the official journal of the Heart Rhythm Society, 2008; 5(6 Suppl): S45-7.
Ogawa Masahiro, Lin Shien-Fong, Weiss James N, Chen Peng-Sheng   Calcium dynamics and ventricular fibrillation Circulation research, 2008; 102(5): e52.
Hayashi Hideki, Kamanu Santosh Dora, Ono Norihiko, Kawase Ayaka, Chou Chung-Chuan, Weiss James N, Karagueuzian Hrayr S, Lin Shien-Fong, Chen Peng-Sheng   Calcium transient dynamics and the mechanisms of ventricular vulnerability to single premature electrical stimulation in Langendorff-perfused rabbit ventricles Heart rhythm : the official journal of the Heart Rhythm Society, 2008; 5(1): 116-23.
Restrepo Juan G, Weiss James N, Karma Alain   Calsequestrin-mediated mechanism for cellular calcium transient alternans Biophysical journal, 2008; 95(8): 3767-89.
de Diego Carlos, Chen Fuhua, Xie Lai-Hua, Dave Amish S, Thu Mya, Rongey Christine, Weiss James N, Valderrábano Miguel   Cardiac alternans in embryonic mouse ventricles American journal of physiology. Heart and circulatory physiology, 2008; 294(1): H433-40.
Yang Ling, Vondriska Thomas M, Han Zhangang, Maclellan W Robb, Weiss James N, Qu Zhilin   Deducing topology of protein-protein interaction networks from experimentally measured sub-networks BMC bioinformatics, 2008; 9(2): 301.
John Scott A, Ottolia Michela, Weiss James N, Ribalet Bernard   Dynamic modulation of intracellular glucose imaged in single cells using a FRET-based glucose nanosensor Pflügers Archiv : European journal of physiology, 2008; 456(2): 307-22.
de Diego Carlos, Pai Rakesh K, Chen Fuhua, Xie Lai-Hua, De Leeuw Jan, Weiss James N, Valderrábano Miguel   Electrophysiological consequences of acute regional ischemia/reperfusion in neonatal rat ventricular myocyte monolayers Circulation, 2008; 118(23): 2330-7.
Yang Jun-Hai, Yang Ling, Qu Zhilin, Weiss James N   Glycolytic oscillations in isolated rabbit ventricular myocytes The Journal of biological chemistry, 2008; 283(52): 36321-7.
Xie Lai-Hua, Sato Daisuke, Garfinkel Alan, Qu Zhilin, Weiss James N   Intracellular Ca alternans: coordinated regulation by sarcoplasmic reticulum release, uptake, and leak Biophysical journal, 2008; 95(6): 3100-10.
Mahajan Aman, Sato Daisuke, Shiferaw Yohannes, Baher Ali, Xie Lai-Hua, Peralta Robert, Olcese Riccardo, Garfinkel Alan, Qu Zhilin, Weiss James N   Modifying L-type calcium current kinetics: consequences for cardiac excitation and arrhythmia dynamics Biophysical journal, 2008; 94(2): 411-23.
Xie Lai-Hua, John Scott A, Ribalet Bernard, Weiss James N   Phosphatidylinositol-4,5-bisphosphate (PIP2) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity The Journal of physiology, 2008; 586(7): 1833-48.
Maclellan W Robb, Wang Yibin, Vondriska Thomas M, Weiss James N, Ping Peipei   Proteomic insights into cardiac cell death and survival Proteomics. Clinical applications, 2008; 2(6): 837-44.
Korge Paavo, Ping Peipei, Weiss James N   Reactive oxygen species production in energized cardiac mitochondria during hypoxia/reoxygenation: modulation by nitric oxide Circulation research, 2008; 103(8): 873-80.
Sovari Ali A, Morita Norishige, Weiss James N, Karagueuzian Hrayr S   Serum transforming growth factor-beta1 as a risk stratifier of sudden cardiac death Medical hypotheses, 2008; 71(2): 262-5.
de Diego Carlos, Pai Rakesh K, Dave Amish S, Lynch Adam, Thu Mya, Chen Fuhua, Xie Lai-Hua, Weiss James N, Valderrábano Miguel   Spatially discordant alternans in cardiomyocyte monolayers American journal of physiology. Heart and circulatory physiology, 2008; 294(3): H1417-25.
Hwang Gyo-Seung, Tang Liang, Joung Boyoung, Morita Norishige, Hayashi Hideki, Karagueuzian Hrayr S, Weiss James N, Lin Shien-Fong, Chen Peng-Sheng   Superiority of biphasic over monophasic defibrillation shocks is attributable to less intracellular calcium transient heterogeneity Journal of the American College of Cardiology, 2008; 52(10): 828-35.
Zhang Jun, Li Xiaohai, Mueller Michael, Wang Yueju, Zong Chenggong, Deng Ning, Vondriska Thomas M, Liem David A, Yang Jeong-In, Korge Paavo, Honda Henry, Weiss James N, Apweiler Rolf, Ping Peipei   Systematic characterization of the murine mitochondrial proteome using functionally validated cardiac mitochondria Proteomics, 2008; 8(8): 1564-75.
Rudy Yoram, Ackerman Michael J, Bers Donald M, Clancy Colleen E, Houser Steven R, London Barry, McCulloch Andrew D, Przywara Dennis A, Rasmusson Randall L, Solaro R John, Trayanova Natalia A, Van Wagoner David R, Varró András, Weiss James N, Lathrop David A   Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary Circulation, 2008; 118(11): 1202-11.
Huffaker Ray B, Samade Richard, Weiss James N, Kogan Boris   Tachycardia-induced early afterdepolarizations: insights into potential ionic mechanisms from computer simulations Computers in biology and medicine, 2008; 38(11-12): 1140-51.
Hayashi Hideki, Lin Shien-Fong, Joung Boyoung, Karagueuzian Hrayr S, Weiss James N, Chen Peng-Sheng   Virtual electrodes and the induction of fibrillation in Langendorff-perfused rabbit ventricles: the role of intracellular calcium American journal of physiology. Heart and circulatory physiology, 2008; 295(4): H1422-8.
Lu Gang, Ren Shuxun, Korge Paavo, Choi Jayoung, Dong Yuan, Weiss James, Koehler Carla, Chen Jau-nian, Wang Yibin   A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development Genes & development, 2007; 21(7): 784-96.
Xie Lai-Hua, John Scott A, Ribalet Bernard, Weiss James N   Activation of inwardly rectifying potassium (Kir) channels by phosphatidylinosital-4,5-bisphosphate (PIP2): interaction with other regulatory ligands Progress in biophysics and molecular biology, 2007; 94(3): 320-35.
Xie Yuanfang, Hu Gang, Sato Daisuke, Weiss James N, Garfinkel Alan, Qu Zhilin   Dispersion of refractoriness and induction of reentry due to chaos synchronization in a model of cardiac tissue Physical review letters, 2007; 99(11): 118101.
Hayashi Hideki, Shiferaw Yohannes, Sato Daisuke, Nihei Motoki, Lin Shien-Fong, Chen Peng-Sheng, Garfinkel Alan, Weiss James N, Qu Zhilin   Dynamic origin of spatially discordant alternans in cardiac tissue Biophysical journal, 2007; 92(2): 448-60.
Huffaker Ray B, Weiss James N, Kogan Boris   Effects of early afterdepolarizations on reentry in cardiac tissue: a simulation study American journal of physiology. Heart and circulatory physiology, 2007; 292(6): H3089-102.
Chen Fuhua, De Diego Carlos, Xie Lai-Hua, Yang Jun-Hai, Klitzner Thomas S, Weiss James N   Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts American journal of physiology. Heart and circulatory physiology, 2007; 293(4): H2472-8.
Sato Daisuke, Shiferaw Yohannes, Qu Zhilin, Garfinkel Alan, Weiss James N, Karma Alain   Inferring the cellular origin of voltage and calcium alternans from the spatial scales of phase reversal during discordant alternans Biophysical journal, 2007; 92(4): L33-5.
Gudzenko Vadim, Shiferaw Yohannes, Savalli Nicoletta, Vyas Roshni, Weiss James N, Olcese Riccardo   Influence of channel subunit composition on L-type Ca2+ current kinetics and cardiac wave stability American journal of physiology. Heart and circulatory physiology, 2007; 293(3): H1805-15.
Xie Fagen, Weiss James N   Interaction and breakup of inwardly rotating spiral waves in an inhomogeneous oscillatory medium Physical review. E, Statistical, nonlinear, and soft matter physics, 2007; 75(1 Pt 2): 016107.
Qu Zhilin, Shiferaw Yohannes, Weiss James N   Nonlinear dynamics of cardiac excitation-contraction coupling: an iterated map study Physical review. E, Statistical, nonlinear, and soft matter physics, 2007; 75(1 Pt 1): 011927.
Soldatov Nikolai M, Weiss James N   Principles of calcium signaling. Salisbury Cove, Maine, June 28-30, 2007 Channels (Austin, Tex.), 2007; 1(3): 218-21.
Chou Chung-Chuan, Zhou Shengmei, Hayashi Hideki, Nihei Motoki, Liu Yen-Bin, Wen Ming-Shien, Yeh San-Jou, Fishbein Michael C, Weiss James N, Lin Shien-Fong, Wu Delon, Chen Peng-Sheng   Remodelling of action potential and intracellular calcium cycling dynamics during subacute myocardial infarction promotes ventricular arrhythmias in Langendorff-perfused rabbit hearts The Journal of physiology, 2007; 580(Pt.3): 895-906.
Baher Ali, Qu Zhilin, Hayatdavoudi Ashkan, Lamp Scott T, Yang Ming-Jim, Xie Fagen, Turner Stephen, Garfinkel Alan, Weiss James N   Short-term cardiac memory and mother rotor fibrillation American journal of physiology. Heart and circulatory physiology, 2007; 292(1): H180-9.
Han Zhangang, Vondriska Thomas M, Yang Ling, Robb MacLellan W, Weiss James N, Qu Zhilin   Signal transduction network motifs and biological memory Journal of theoretical biology, 2007; 246(4): 755-61.
Ono Norihiko, Hayashi Hideki, Kawase Ayaka, Lin Shien-Fong, Li Hongmei, Weiss James N, Chen Peng-Sheng, Karagueuzian Hrayr S   Spontaneous atrial fibrillation initiated by triggered activity near the pulmonary veins in aged rats subjected to glycolytic inhibition American journal of physiology. Heart and circulatory physiology, 2007; 292(1): H639-48.
Qu Zhilin, Weiss James N   The chicken or the egg? Voltage and calcium dynamics in the heart American journal of physiology. Heart and circulatory physiology, 2007; 293(4): H2054-5.
Yang Ming-Jim, Tran Diana X, Weiss James N, Garfinkel Alan, Qu Zhilin   The pinwheel experiment revisited: effects of cellular electrophysiological properties on vulnerability to cardiac reentry American journal of physiology. Heart and circulatory physiology, 2007; 293(3): H1781-90.
Tran Diana X, Yang Ming-Jim, Weiss James N, Garfinkel Alan, Qu Zhilin   Vulnerability to re-entry in simulated two-dimensional cardiac tissue: effects of electrical restitution and stimulation sequence Chaos (Woodbury, N.Y.), 2007; 17(4): 043115.
Hwang Gyo-Seung, Hayashi Hideki, Tang Liang, Ogawa Masahiro, Hernandez Heidy, Tan Alex Y, Li Hongmei, Karagueuzian Hrayr S, Weiss James N, Lin Shien-Fong, Chen Peng-Sheng   Intracellular calcium and vulnerability to fibrillation and defibrillation in Langendorff-perfused rabbit ventricles Circulation, 2006; 114(24): 2595-603.

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