Andrew Saxon, M.D.

Work Titles
UCLA Physician, Clinical Immunology and Allergy Professor Emeritus, Medicine Professor Emeritus, Clinical Immunology and Allergy
M.D., Harvard Medical School, 1972
1975 - 1977 UCLA School of Medicine
1972 - 1973 Harbor - UCLA Medical Center
1973 - 1975 Harbor - UCLA Medical Center
1990 American Board of Internal Medicine
1979 American Board of Allergy and Immunology
1975 American Board of Internal Medicine

Contact Information:

Work Email Address:



Mailing Address:

BOX 951680, 37-131 CHS
Los Angeles, CA 90095


A selected list of publications:

Lin Erina, Saxon Andrew, Riedl Marc   Penicillin allergy: value of including amoxicillin as a determinant in penicillin skin testing International archives of allergy and immunology, 2010; 152(4): 313-8.
Behnecke Anne, Li Wei, Chen Ling, Saxon Andrew, Zhang Ke   IgE-mediated allergen gene vaccine platform targeting human antigen-presenting cells through the high-affinity IgE receptor The Journal of allergy and clinical immunology, 2009; 124(1): 108-13.
Riedl Marc A, Saxon Andrew, Diaz-Sanchez David   Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway Clinical immunology (Orlando, Fla.), 2009; 130(3): 244-51.
Zhang Ke, Behnecke Anne, Li Wei, Saxon Andrew   A novel multi-potential dendritic cell targeted gene vaccination platform; application to food allergy and beyond Arbeiten aus dem Paul-Ehrlich-Institut (Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel) Langen/Hessen, 2009; 96(2): 338-47; discussion 348.
Saxon Andrew   "Who-mab's on first and what-cept's on second. I don't know--third base" Clinical immunology (Orlando, Fla.), 2008; 127(3): 267.
Saxon Andrew, Kepley Chris, Zhang Ke   "Accentuate the negative, eliminate the positive": engineering allergy therapeutics to block allergic reactivity through negative signaling The Journal of allergy and clinical immunology, 2008; 121(2): 320-5.
Mertsching Elisabeth, Bafetti Lisa, Hess Henry, Perper Stuart, Giza Keith, Allen Lisa Chan, Negrou Ella, Hathaway Karen, Hopp Jennifer, Chung Julie, Perret Daniel, Shields Michael, Saxon Andrew, Kehry Marilyn R   A mouse Fcgamma-Fcepsilon protein that inhibits mast cells through activation of FcgammaRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases The Journal of allergy and clinical immunology, 2008; 121(2): 441-447.e5.
Allen Lisa Chan, Kepley Christopher L, Saxon Andrew, Zhang Ke   Modifications to an Fcgamma-Fcvarepsilon fusion protein alter its effectiveness in the inhibition of FcvarepsilonRI-mediated functions The Journal of allergy and clinical immunology, 2007; 120(2): 462-8.
Zhang Ke, Zhu Daocheng, Kepley Christopher, Terada Tetsuya, Saxon Andrew   Chimeric human fcgamma-allergen fusion proteins in the prevention of allergy Immunology and allergy clinics of North America, 2007; 27(1): 93-103.
Hardin Bryan D, Kelman Bruce J, Saxon Andrew   Nondisclosure of conflicts of interest is perilous to the advancement of science The Journal of allergy and clinical immunology, 2007; 119(1): 256-7.
Terada Tetsuya, Zhang Ke, Belperio John, Londhe Vedang, Saxon Andrew   A chimeric human-cat Fcgamma-Fel d1 fusion protein inhibits systemic, pulmonary, and cutaneous allergic reactivity to intratracheal challenge in mice sensitized to Fel d1, the major cat allergen Clinical immunology (Orlando, Fla.), 2006; 120(1): 45-56.
Saxon Andrew, Zhu Daocheng, Zhang Ke, Chan Lisa A, Kepley Christopher L   Recent advances in the use of genetically engineered negative signaling molecules to treat allergic diseases Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M, 2006; 26(95): 223-31; discussion 231-3.
Bush Robert K, Portnoy Jay M, Saxon Andrew, Terr Abba I, Wood Robert A   The medical effects of mold exposure The Journal of allergy and clinical immunology, 2006; 117(2): 326-33.
Riedl Marc A, Landaw Elliot M, Saxon Andrew, Diaz-Sanchez David   Initial high-dose nasal allergen exposure prevents allergic sensitization to a neoantigen Journal of immunology (Baltimore, Md. : 1950), 2005; 174(11): 7440-5.
Yamada Takechiyo, Zhang Ke, Yamada Akiko, Zhu Daocheng, Saxon Andrew   B lymphocyte stimulator activates p38 mitogen-activated protein kinase in human Ig class switch recombination American journal of respiratory cell and molecular biology, 2005; 32(5): 388-94.
Zhu Daocheng, Kepley Christopher L, Zhang Ke, Terada Tetsuya, Yamada Takechiyo, Saxon Andrew   A chimeric human-cat fusion protein blocks cat-induced allergy Nature medicine, 2005; 11(4): 446-9.
Saxon Andrew, Diaz-Sanchez David   Air pollution and allergy: you are what you breathe Nature immunology, 2005; 6(3): 223-6.
Saxon Andrew, Zhu Daocheng, Zhang Ke, Allen Lisa Chan, Kepley Christopher L   Genetically engineered negative signaling molecules in the immunomodulation of allergic diseases Current opinion in allergy and clinical immunology, 2004; 4(6): 563-8.
Corren Jonathan, Diaz-Sanchez David, Saxon Andrew, Deniz Yamo, Reimann James, Sinclair Don, Davancaze Teresa, Adelman Daniel   Effects of omalizumab, a humanized monoclonal anti-IgE antibody, on nasal reactivity to allergen and local IgE synthesis Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004; 93(3): 243-8.
Zhang Ke, Kepley Christopher L, Terada Tetsuya, Zhu Daocheng, Perez Hector, Saxon Andrew   Inhibition of allergen-specific IgE reactivity by a human Ig Fcgamma-Fcepsilon bifunctional fusion protein The Journal of allergy and clinical immunology, 2004; 114(2): 321-7.
Saxon Andrew, Hardin Bryan D, Kelman Bruce J   Exposure-dose-response: critical considerations in toxicology and immunology alike The Journal of allergy and clinical immunology, 2004; 114(1): 207; author reply 207-8.
Saxon Andrew, Macy Eric   Cross-reactivity and sulfonamide antibiotics The New England journal of medicine, 2004; 350(3): 302-3; author reply 302-3.
Gilliland Frank D, Li Yu-Fen, Saxon Andrew, Diaz-Sanchez David   Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study Lancet, 2004; 363(9403): 119-25.
Saxon Andrew   Primary immunodeficiencies: rare disorders in the era of global medicine Clinical immunology (Orlando, Fla.), 2003; 109(3): 249.
Bastain Theresa M, Gilliland Frank D, Li Yu Fen, Saxon Andrew, Diaz-Sanchez David   Intraindividual reproducibility of nasal allergic responses to diesel exhaust particles indicates a susceptible phenotype Clinical immunology (Orlando, Fla.), 2003; 109(2): 130-6.
Kepley Christopher L, Zhang Ke, Zhu Daocheng, Saxon Andrew   FcepsilonRI-FcgammaRII coaggregation inhibits IL-16 production from human Langerhans-like dendritic cells Clinical immunology (Orlando, Fla.), 2003; 108(2): 89-94.
Yamada Takechiyo, Zhu Daocheng, Zhang Ke, Saxon Andrew   Inhibition of interleukin-4-induced class switch recombination by a human immunoglobulin Fc gamma-Fc epsilon chimeric protein The Journal of biological chemistry, 2003; 278(35): 32818-24.
Zhou Cheng, Saxon Andrew, Zhang Ke   Human activation-induced cytidine deaminase is induced by IL-4 and negatively regulated by CD45: implication of CD45 as a Janus kinase phosphatase in antibody diversification Journal of immunology (Baltimore, Md. : 1950), 2003; 170(4): 1887-93.
Zhang Ke, Zhang Ling, Zhu Daocheng, Bae David, Nel Andre, Saxon Andrew   CD40-mediated p38 mitogen-activated protein kinase activation is required for immunoglobulin class switch recombination to IgE The Journal of allergy and clinical immunology, 2002; 110(3): 421-8.
Yamada Takechiyo, Zhu Daocheng, Saxon Andrew, Zhang Ke   CD45 controls interleukin-4-mediated IgE class switch recombination in human B cells through its function as a Janus kinase phosphatase The Journal of biological chemistry, 2002; 277(32): 28830-5.
Zhu Daocheng, Kepley Christopher L, Zhang Min, Zhang Ke, Saxon Andrew   A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulation Nature medicine, 2002; 8(5): 518-21.
Devouassoux Gilles, Saxon Andrew, Metcalfe Dean D, Prussin Calman, Colomb Maurice G, Brambilla Christian, Diaz-Sanchez David   Chemical constituents of diesel exhaust particles induce IL-4 production and histamine release by human basophils The Journal of allergy and clinical immunology, 2002; 109(5): 847-53.
Zhang Ke, Zhang Ling, Yamada Takechiyo, Vu Michael, Lee Anna, Saxon Andrew   Efficiency of Iepsilon promoter-directed switch recombination in GFP expression-based switch constructs works synergistically with other promoter and/or enhancer elements but is not tightly linked to the strength of transcription European journal of immunology, 2002; 32(2): 424-34.

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