Publications:
A selected list of publications:
Takayuki Ohnishi, Masako Yanazawa1, Tomoya Sasahara, Yasuki Kitamura, Hidekazu Hiroaki, Yugo Fukazawa, Isao Kii, Takashi Nishiyama, Akiyoshi Kakita, Hiroyuki Takeda, Akihide Takeuchi, Yoshie Arai, Akane Ito, Hitomi Komura, Hajime Hirao, Kaori Satomura, Masafumi Inoue, Shin-ichi Muramatsu, Ko Matsui, Mari Tadag, Michio Sato, Eri Saijo, Yoshiki Shigemitsu, Satoko Sakai, Yoshitaka Umetsu, Natsuko Godd, Naomi Takino, Hitoshi Takahashi, Masatoshi Hagiwara, Tatsuya Sawasaki, Genji Iwasaki, Yu Nakamura, Yo-ichi Nabeshima, David B. Teplow, and Minako Hoshi
Na,K-ATPaseα3 Is a Death Target of Alzheimer Patient Amyloid-β Assembly
PNAS,
2015;
.
Do, Thanh; Economou, Nicholas; LaPointe, Nichole; Kincannon, William; Bleiholder, Christian; Feinstein, Stuart; Teplow, David; Buratto, Steven; Bowers, Michael
Factors That Drive Peptide Assembly and Fibril Formation: Experimental and Theoretical Analysis of Sup35 NNQQNY Mutants
J Phys Chem B,
2013; 117:8436-46:
.
Jun Wang, Mario G. Ferruzzi, Lap Ho, Jack Blount, Elsa M. Janle, Bing Gong, Yong Pan, G. A. Nagana Gowda, Daniel Raftery, Isabel Arrieta-Cruz, Vaishali Sharma, Bruce Cooper, Jessica Lobo, James E. Simon, Chungfen Zhang, Alice Cheng, Xianjuan Qian, Kenjiro Ono, David B. Teplow, Constantine Pavlides, Richard A. Dixon, and Giulio M. Pasinetti
Brain-Targeted Proanthocyanidin Metabolites for Alzheimer's Disease Treatment
J Neuroscience,
2012; (32):
5144-5150.
Ono K, Li L, Takamura Y, Yoshiike Y, Zhu L, Han F, Mao X, Ikeda T, Takasaki JI, Nishijo H, Takashima A, Teplow DB, Zagorski MG, Yamada M.
Phenolic compounds prevent amyloid β-protein oligomerization and synaptic dysfunction by site specific binding.
J Biol Chem,
2012; 287:14631-14643.:
.
Robin Roychaudhuri, Mingfeng Yang, Atul Deshpande, Gregory M.
Cole, Sally Frautschy, Aleksey Lomakin, George B. Benedek, and David B. Teplow
C-terminal turn stability determines assembly differences between Aβ40 and Aβ42,
J Mol Biol, in press,
2012;
.
Roychaudhuri R, Condron MM, Lazo ND, and Teplow DB
Structural dynamics of the amyloid β-protein monomer folding nucleus. Biochem, in press,
(This publication was highlighted on the journal's home page),
2012;
.
Ono K, Condron MM, and Teplow DB
Effects of the English (H6R) and Tottori (D7N) familial Alzheimer disease mutations on amyloid β-protein assembly and toxicity,
JBC, 285:23186?23197,
2010;
.
Urbanc B, Betnel M, Cruz L, Bitan G, Teplow DB
Elucidation of amyloid β-protein oligomerization mechanisms: Discrete molecular dynamics study,
JACS, 132:4266?4280,
2010;
.
Maji SK, Ogorzalek Loo RR, Spring SM, Vollers SS, Condron MM, Bitan G, Loo JA, and Teplow DB
Amino acid position-specific contributions to amyloid β-protein oligomerization,
J Biol Chem, 284:23580?23591,
2009;
.
Roychaudhuri R, Yang M, Hoshi MM, Teplow DB
Amyloid β-protein assembly and Alzheimer's disease,
J Biol Chem, 284:4749?4753,
2009;
.
Ono K, Condron MM, Teplow DB
Structure-neurotoxicity relationships of amyloid β-protein oligomers,
PNAS, 106:14745-14750,
2009;
.
Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, and Teplow DB
Effects of grape seed-derived polyphenols on amyloid β-protein self-assembly and cytotoxicity,
J. Biol Chem, 283: 32176? 32187. (JBC ?Paper of the Week?),
2008;
.
Grant MA, Lazo ND, Lomakin A, Condron MM, Arai H, Yamin G, Rigby AC, and Teplow DB
Familial Alzheimer's disease mutations alter the stability of the amyloid β-protein monomer folding nucleus,
PNAS, 104: 16522-16527,
2007;
.
Maji SK, Amsden JJ, Rothschild KJ, Condron MM, Teplow DB
Conformational dynamics of Aβ assembly probed using intrinsic fluorescence,
Biochemistry 44:13365-13376,
2005;
.
Lazo ND, Grant MA, Condron MM, Rigby AC, Teplow DB
On the nucleation of amyloid β-protein monomer folding,
Prot Sci, 14:1581-1596,
2005;
.
Lazo ND, Grant MA, Condron MM, Rigby AC, Teplow DB
On the nucleation of amyloid β protein monomer folding,
Prot Sci, 14:1581-1596,
2005;
.
Bitan G, Tarus B, Vollers SS, Lashuel HA, Condron MM, Straub JE,
Teplow DB
A molecular switch in amyloid assembly: Met35 and amyloid β-protein oligomerization,
J Am Chem Soc, 50:15359-15365,
2003;
.
Bitan G, Kirkitadze MD, Lomakin A, Vollers SS, Benedek GB, Teplow DB
Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways,
Proc Natl Acad Sci USA, 100:330-335,
2003;
.
Bitan G, Vollers SS, Teplow DB
Elucidation of primary structure elements controlling early amyloid β-protein oligomerization,
J Biol Chem, 278:34882-34889,
2003;
.
Bitan G, Lomakin A, Teplow DB
Amyloid β-protein oligomerization. Prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins,
J Biol Chem, 276: 35176-35184,
2001;
.
Kirkitadze MD, Condron MM, Teplow DB
Identification and characterization of key kinetic intermediates in amyloid β-protein fibrillogenesis,
J Mol Biol 312:1103-1119,
2001;
.
Walsh DM, Hartley DM, Fezoui Y, Condron MM, Lomakin A, Kusumoto Y, Benedek GB, Selkoe DJ, Teplow DB
Amyloid β-protein fibrillogenesis: Structure and biological activity of protofibrillar intermediates,
J Biol Chem, 274:25945-25952,
1999;
.
Walsh DM, Lomakin A, Benedek GB, Condron MM, Teplow DB
Amyloid β-protein fibrillogenesis: Detection of a protofibrillar intermediate,
J Biol Chem. 272:22364-22372,
1997;
.
Lomakin A, Chung DS, Benedek GB, Kirschner DA, Teplow DB
On the nucleation and growth of amyloid β-protein fibrils: Detection of nuclei and quantitation of rate constants,
Proc Natl Acad Sci USA 93:1125-1129,
1996;
.