Sherven Sharma, Ph.D.

Edit your Faculty Profile

A Short Biography:

Fiji's own Dr Sherven Sharma, an alumnus of USP, graduated in 1983 majoring in Physics, Chemistry and Mathematics; the same year he lost his mother to pancreatic cancer. This was a significant moment that paved a career investigating the biological characteristics of cancer for the development of novel therapeutics. After completing a Doctorate of Philosophy in Microbiology from the University of Southern California's School of Medicine, he initiated studies on immunological targeting of cancer in a collaborative environment at the University of California Los Angeles (UCLA). Dr Sharma is currently a Professor at UCLA and Director of Molecular Medicine at Veterans Affairs Greater Los Angeles Health Care System. He has more than 90 publications in peer-reviewed journals.
Work Titles
CTSI Member, CTSI
California NanoSystems Institute Member, California NanoSystems Institute
UCLA Professor, Medicine Member, Tumor Immunology Program at the Jonsson Comprehensive Cancer Center (JCCC)
Education:
Degrees:
Ph.D., University of Southern California, 1993
B.S., University of South Pacific, Fiji Islands, 1979 - 1983
Academic Experience:
1993 - 1996 University of California, Los Angeles, Tumor Immunology

Contact Information:

Email Address:

ssharma@mednet.ucla.edu

Work Email Address:

sharmasp@ucla.edu

Work Email Address:

ssharma@mednet.ucla.edu


Website:

http://www.lung.med.ucla.edu/home.htm
Web-Profile

Fax Number:

310-268-4164

Work Phone Number:

310-478-3711

Mailing Address:

UCLA Med-Pul & Critical Care
BOX 951690, 37-131 CHS
Los Angeles, CA 90095


Office Address:

Main Office
11301 Wilshire Blvd.
Los Angeles, CA 90073


Publications:

A selected list of publications:

Sharma Sherven, Zhu Li, Davoodi Michael, Harris-White Marni, Lee Jay M, St John Maie, Salgia Ravi, Dubinett Steven   TLR3 agonists and proinflammatory antitumor activities Expert opinion on therapeutic targets, 2013; 17(5): 481-3.
Hu David, Lau Ontario D, Wang Linda, Wang Guanyu, Schaue Dorthe, Zhu Li, Huang Min, Lin Yuan, Dennis Miranda, Abemayor Elliot, Elashoff David A, Dubinett Steven M, McBride William H, Sharma Sherven, Wu Ben, St John Maie A   A novel modular polymer platform for the treatment of head and neck squamous cell carcinoma in an animal model Archives of otolaryngology--head & neck surgery, 2012; 138(4): 412-7.
Sharma Sherven, Dubinett Steven, Salgia Ravi   CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer American journal of respiratory and critical care medicine, 2012; 186(10): 940-1.
Srivastava Minu K, Zhu Li, Harris-White Marni, Kar Upendra, Huang Min, Johnson Ming F, Lee Jay M, Elashoff David, Strieter Robert, Dubinett Steven, Sharma Sherven   Myeloid suppressor cell depletion augments antitumor activity in lung cancer PloS one, 2012; 7(7): e40677.
Srivastava Minu K, Andersson Åsa, Zhu Li, Harris-White Marni, Lee Jay M, Dubinett Steven, Sharma Sherven   Myeloid suppressor cells and immune modulation in lung cancer Immunotherapy, 2012; 4(3): 291-304.
Rettig Matthew, Trinidad Kenny, Pezeshkpour G, Frost Patrick, Sharma Sherven, Moatamed Farhad, Tamanoi Fuyuhiko, Mortazavi Fariborz   PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells PloS one, 2012; 7(7): e42012.
Wang Guanyu, Zhang Jiawei, Liu Luying, Sharma Sherven, Dong Qinghua   Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl PloS one, 2012; 7(12): e51764.
Dennis Miranda, Wang Guanyu, Luo Jie, Lin Yuan, Dohadwala Mariam, Abemayor Elliot, Elashoff David A, Sharma Sherven, Dubinett Steven M, St John Maie A   Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2012; 147(4): 726-32.
Srivastava Minu K, Dubinett Steven, Sharma Sherven   Targeting MDSCs enhance therapeutic vaccination responses against lung cancer Oncoimmunology, 2012; 1(9): 1650-1651.
Kar Upendra K, Jiang Janina, Champion Cheryl I, Salehi Sahar, Srivastava Minu, Sharma Sherven, Rabizadeh Shahrooz, Niazi Kayvan, Kickhoefer Valerie, Rome Leonard H, Kelly Kathleen A   Vault nanocapsules as adjuvants favor cell-mediated over antibody-mediated immune responses following immunization of mice PloS one, 2012; 7(7): e38553.
Sharma Sherven, Srivastava Minu K, Harris-White Marni, Lee Jay Moon, Dubinett Steven   MUC1 peptide vaccine mediated antitumor activity in non-small cell lung cancer Expert opinion on biological therapy, 2011; 11(8): 987-90.
Kar Upendra K, Srivastava Minu K, Andersson Asa, Baratelli Felicita, Huang Min, Kickhoefer Valerie A, Dubinett Steven M, Rome Leonard H, Sharma Sherven   Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth PloS one, 2011; 6(5): e18758.
Andersson Asa, Srivastava Minu K, Harris-White Marni, Huang Min, Zhu Li, Elashoff David, Strieter Robert M, Dubinett Steven M, Sharma Sherven   Role of CXCR3 ligands in IL-7/IL-7R alpha-Fc-mediated antitumor activity in lung cancer Clinical cancer research : an official journal of the American Association for Cancer Research, 2011; 17(11): 3660-72.
Dubinett Steven M, Lee Jay M, Sharma Sherven, Mulé James J   Chemokines: can effector cells be redirected to the site of the tumor? Cancer journal (Sudbury, Mass.), 2010; 16(4): 325-35.
Herrmann Ines, Baeuerle Patrick A, Friedrich Matthias, Murr Alexander, Filusch Susanne, Rüttinger Dominik, Majdoub Mariam W, Sharma Sherven, Kufer Peter, Raum Tobias, Münz Markus   Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells PloS one, 2010; 5(10): e13474.
Baratelli Felicita, Lee Jay M, Hazra Saswati, Lin Ying, Walser Tonya C, Schaue Dorthe, Pak Peter S, Elashoff David, Reckamp Karen, Zhang Ling, Fishbein Michael C, Sharma Sherven, Dubinett Steven M   PGE(2) contributes to TGF-beta induced T regulatory cell function in human non-small cell lung cancer American journal of translational research, 2010; 2(4): 356-67.
Sharma Sherven, Andersson Asa   Adenovirus E3 proteins help tumors to evade innate and adaptive immune responses Cancer biology & therapy, 2009; 8(12): 1133-5.
Veena Mysore S, Qin Min, Andersson Asa, Sharma Sherven, Batra Raj K   CAR mediates efficient tumor engraftment of mesenchymal type lung cancer cells Laboratory investigation; a journal of technical methods and pathology, 2009; 89(8): 875-86.
Andersson Asa, Yang Seok-Chul, Huang Min, Zhu Li, Kar Upendra K, Batra Raj K, Elashoff David, Strieter Robert M, Dubinett Steven M, Sharma Sherven   IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer Journal of immunology (Baltimore, Md. : 1950), 2009; 182(11): 6951-8.
St John Maie A, Dohadwala Mariam, Luo Jie, Wang Guanyu, Lee Gina, Shih Hubert, Heinrich Eileen, Krysan Kostantyn, Walser Tonya, Hazra Saswati, Zhu Li, Lai Chi, Abemayor Elliot, Fishbein Michael, Elashoff David A, Sharma Sherven, Dubinett Steven M   Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma Clinical cancer research : an official journal of the American Association for Cancer Research, 2009; 15(19): 6018-27.
Yanagawa Jane, Walser Tonya C, Zhu Li X, Hong Longsheng, Fishbein Michael C, Mah Vei, Chia David, Goodglick Lee, Elashoff David A, Luo Jie, Magyar Clara E, Dohadwala Mariam, Lee Jay M, St John Maie A, Strieter Robert M, Sharma Sherven, Dubinett Steven M   Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma Clinical cancer research : an official journal of the American Association for Cancer Research, 2009; 15(22): 6820-9.
Basak Saroj K, Veena Mysore S, Oh Scott, Huang Ge, Srivatsan Eri, Huang Min, Sharma Sherven, Batra Raj K   The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer PloS one, 2009; 4(6): e5884.
Dubinett Steven, Sharma Sherven   Towards effective immunotherapy for lung cancer: simultaneous targeting of tumor-initiating cells and immune pathways in the tumor microenvironment Immunotherapy, 2009; 1(5): 721-5.
Lee Jay M, Yanagawa Jane, Peebles Katherine A, Sharma Sherven, Mao Jenny T, Dubinett Steven M   Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment Critical reviews in oncology/hematology, 2008; 66(3): 208-17.
Krysan Kostyantyn, Lee Jay M, Dohadwala Mariam, Gardner Brian K, Reckamp Karen L, Garon Edward, St John Maie, Sharma Sherven, Dubinett Steven M   Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2008; 3(2): 107-10.
Baratelli Felicita, Takedatsu Hiroko, Hazra Saswati, Peebles Katherine, Luo Jie, Kurimoto Pam S, Zeng Gang, Batra Raj K, Sharma Sherven, Dubinett Steven M, Lee Jay M   Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer Journal of translational medicine, 2008; 6(3): 38.
Walser Tonya, Cui Xiaoyan, Yanagawa Jane, Lee Jay M, Heinrich Eileen, Lee Gina, Sharma Sherven, Dubinett Steven M   Smoking and lung cancer: the role of inflammation Proceedings of the American Thoracic Society, 2008; 5(8): 811-5.
Hazra Saswati, Peebles Katherine A, Sharma Sherven, Mao Jenny T, Dubinett Steven M   The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer PPAR research, 2008; 2008(2): 790568.
Reckamp Karen L, Gardner Brian K, Figlin Robert A, Elashoff David, Krysan Kostyantyn, Dohadwala Mariam, Mao Jenny, Sharma Sherven, Inge Landon, Rajasekaran Ayyappan, Dubinett Steven M   Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2008; 3(2): 117-24.
Liu Ming, Yang Seok-Chul, Sharma Sherven, Luo Jie, Cui Xiaoyan, Peebles Katherine A, Huang Min, Sato Mitsuo, Ramirez Ruben D, Shay Jerry W, Minna John D, Dubinett Steven M   EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells American journal of respiratory cell and molecular biology, 2007; 37(5): 578-88.
Peebles Katherine A, Lee Jay M, Mao Jenny T, Hazra Saswati, Reckamp Karen L, Krysan Kostyantyn, Dohadwala Mariam, Heinrich Eileen L, Walser Tonya C, Cui Xiaoyan, Baratelli Felicita E, Garon Edward, Sharma Sherven, Dubinett Steven M   Inflammation and lung carcinogenesis: applying findings in prevention and treatment Expert review of anticancer therapy, 2007; 7(10): 1405-21.
Hazra Saswati, Batra Raj K, Tai Hsin H, Sharma Sherven, Cui Xiaoyan, Dubinett Steven M   Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase Molecular pharmacology, 2007; 71(6): 1715-20.
Pan Judong, Burdick Marie D, Belperio John A, Xue Ying Ying, Gerard Craig, Sharma Sherven, Dubinett Steven M, Strieter Robert M   CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis Journal of immunology (Baltimore, Md. : 1950), 2006; 176(3): 1456-64.
Dohadwala Mariam, Yang Seok-Chul, Luo Jie, Sharma Sherven, Batra Raj K, Huang Min, Lin Ying, Goodglick Lee, Krysan Kostyantyn, Fishbein Michael C, Hong Longsheng, Lai Chi, Cameron Robert B, Gemmill Robert M, Drabkin Harry A, Dubinett Steven M   Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer Cancer research, 2006; 66(10): 5338-45.
Cui Xiaoyan, Yang Seok-Chul, Sharma Sherven, Heuze-Vourc'h Nathalie, Dubinett Steven M   IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer Biochemical and biophysical research communications, 2006; 343(4): 995-1001.
Yang Seok-Chul, Batra Raj K, Hillinger Sven, Reckamp Karen L, Strieter Robert M, Dubinett Steven M, Sharma Sherven   Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma Cancer research, 2006; 66(6): 3205-13.
Hoang Bao, Zhu Li, Shi Yijiang, Frost Patrick, Yan Huajun, Sharma Sanjai, Sharma Sherven, Goodglick Lee, Dubinett Steven, Lichtenstein Alan   Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance Blood, 2006; 107(11): 4484-90.
Krysan Kostyantyn, Reckamp Karen L, Sharma Sherven, Dubinett Steven M   The potential and rationale for COX-2 inhibitors in lung cancer Anti-cancer agents in medicinal chemistry, 2006; 6(3): 209-20.
Mao Jenny T, Cui Xiaoyan, Reckamp Karen, Liu Ming, Krysan Kostyantyn, Dalwadi Harnisha, Sharma Sherven, Hazra Saswati, Strieter Robert, Gardner Brian, Dubinett Steven M   Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer Clinical lung cancer, 2005; 7(1): 30-9.
Sharma Sherven, Zhu Li, Yang Seok Chul, Zhang Ling, Lin Jeff, Hillinger Sven, Gardner Brian, Reckamp Karen, Strieter Robert M, Huang Min, Batra Raj K, Dubinett Steven M   Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses Journal of immunology (Baltimore, Md. : 1950), 2005; 175(2): 813-9.
Dalwadi Harnisha, Krysan Kostyantyn, Heuze-Vourc'h Nathalie, Dohadwala Mariam, Elashoff David, Sharma Sherven, Cacalano Nicholas, Lichtenstein Alan, Dubinett Steven   Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer Clinical cancer research : an official journal of the American Association for Cancer Research, 2005; 11(21): 7674-82.
Qin Min, Escuadro Brian, Sharma Sherven, Batra Raj K   Gene transfer mediated by native versus fibroblast growth factor-retargeted adenoviral vectors into lung cancer cells American journal of respiratory cell and molecular biology, 2005; 32(3): 211-7.
Heuzé-Vourc'h Nathalie, Liu Ming, Dalwadi Harnisha, Baratelli Felicita E, Zhu Li, Goodglick Lee, Põld Mehis, Sharma Sherven, Ramirez Ruben D, Shay Jerry W, Minna John D, Strieter Robert M, Dubinett Steven M   IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression Biochemical and biophysical research communications, 2005; 333(2): 470-5.
Baratelli Felicita, Krysan Kostyantyn, Heuzé-Vourc'h Nathalie, Zhu Li, Escuadro Brian, Sharma Sherven, Reckamp Karen, Dohadwala Mariam, Dubinett Steven M   PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells Journal of leukocyte biology, 2005; 78(2): 555-64.
Krysan Kostyantyn, Reckamp Karen L, Dalwadi Harnisha, Sharma Sherven, Rozengurt Enrique, Dohadwala Mariam, Dubinett Steven M   Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner Cancer research, 2005; 65(14): 6275-81.
Baratelli Felicita, Lin Ying, Zhu Li, Yang Seok-Chul, Heuzé-Vourc'h Nathalie, Zeng Gang, Reckamp Karen, Dohadwala Mariam, Sharma Sherven, Dubinett Steven M   Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells Journal of immunology (Baltimore, Md. : 1950), 2005; 175(3): 1483-90.
Gamradt Seth C, Feeley Brian T, Liu Nancy Q, Roostaeian Jason, Lin Ying Q, Zhu Li X, Sharma Sherven, Dubinett Steven M, Lieberman Jay R   The effect of cyclooxygenase-2 (COX-2) inhibition on human prostate cancer induced osteoblastic and osteolytic lesions in bone Anticancer research, 2005; 25(1A): 107-15.
Sharma Sherven, Yang Seok-Chul, Zhu Li, Reckamp Karen, Gardner Brian, Baratelli Felicita, Huang Min, Batra Raj K, Dubinett Steven M   Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer Cancer research, 2005; 65(12): 5211-20.
Qin Min, Escuadro Brian, Dohadwala Mariam, Sharma Sherven, Batra Raj K   A novel role for the coxsackie adenovirus receptor in mediating tumor formation by lung cancer cells Cancer research, 2004; 64(18): 6377-80.
Krysan Kostyantyn, Merchant Farrukh H, Zhu Li, Dohadwala Mariam, Luo Jie, Lin Ying, Heuze-Vourc'h Nathalie, Põld Mehis, Seligson David, Chia David, Goodglick Lee, Wang Hejing, Strieter Robert, Sharma Sherven, Dubinett Steven   COX-2-dependent stabilization of survivin in non-small cell lung cancer FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004; 18(1): 206-8.
Strieter Robert M, Belperio John A, Burdick Marie D, Sharma Sherven, Dubinett Steven M, Keane Michael P   CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer Annals of the New York Academy of Sciences, 2004; 1028(1A): 351-60.
Gardner Brian, Zhu Li X, Roth Michael D, Tashkin Donald P, Dubinett Steven M, Sharma Sherven   Cocaine modulates cytokine and enhances tumor growth through sigma receptors Journal of neuroimmunology, 2004; 147(1-2): 95-8.
Krysan Kostyantyn, Dalwadi Harnisha, Sharma Sherven, Põld Mehis, Dubinett Steven   Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer Cancer research, 2004; 64(18): 6359-62.
Põld Mehis, Krysan Kostyantyn, Põld Anu, Dohadwala Mariam, Heuze-Vourc'h Nathalie, Mao Jenny T, Riedl Karen L, Sharma Sherven, Dubinett Steven M   Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer Cancer research, 2004; 64(18): 6549-55.
Põld Mehis, Zhu Li X, Sharma Sherven, Burdick Marie D, Lin Ying, Lee Peter P N, Põld Anu, Luo Jie, Krysan Kostyantyn, Dohadwala Mariam, Mao Jenny T, Batra Raj K, Strieter Robert M, Dubinett Steven M   Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer Cancer research, 2004; 64(5): 1853-60.
Krysan Kostyantyn, Dohadwala Mariam, Luo Jie, Lin Ying, Zhu Li, Heuze-Vourc'h Nathalie, Goodglick Lee, Merchant Farrukh, Seligson David, Pold Mehis, Strieter Robert, Sharma Sherven, Dubinett Steven   Cyclooxygenase-2-dependent expression of survivin in non-small cell lung cancer Chest, 2004; 125(5 Suppl): 140S.
Zhang Ling, Keane Michael P, Zhu Li X, Sharma Sherven, Rozengurt Enrique, Strieter Robert M, Dubinett Steven M, Huang Min   Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis The Journal of biological chemistry, 2004; 279(27): 28315-9.
Yang Seok-Chul, Hillinger Sven, Riedl Karen, Zhang Ling, Zhu Li, Huang Min, Atianzar Kimberly, Kuo Brian Y, Gardner Brian, Batra Raj K, Strieter Robert M, Dubinett Steven M, Sharma Sherven   Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity Clinical cancer research : an official journal of the American Association for Cancer Research, 2004; 10(8): 2891-901.
Riedl Karen, Krysan Kostyantyn, Põld Mehis, Dalwadi Harnisha, Heuze-Vourc'h Nathalie, Dohadwala Mariam, Liu Ming, Cui Xiaoyan, Figlin Robert, Mao Jenny T, Strieter Robert, Sharma Sherven, Dubinett Steven M   Multifaceted roles of cyclooxygenase-2 in lung cancer Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2004; 7(3): 169-84.
Baratelli Felicita E, Heuzé-Vourc'h Nathalie, Krysan Kostyantyn, Dohadwala Mariam, Riedl Karen, Sharma Sherven, Dubinett Steven M   Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix Journal of immunology (Baltimore, Md. : 1950), 2004; 173(9): 5458-66.
Heuze-Vourc'h Nathalie, Zhu Li, Krysan Kostyantyn, Batra Raj K, Sharma Sherven, Dubinett Steven M   Abnormal interleukin 10Ralpha expression contributes to the maintenance of elevated cyclooxygenase-2 in non-small cell lung cancer cells Cancer research, 2003; 63(4): 766-70.
Qin Min, Chen Shuang, Yu Tina, Escuadro Brian, Sharma Sherven, Batra Raj K   Coxsackievirus adenovirus receptor expression predicts the efficiency of adenoviral gene transfer into non-small cell lung cancer xenografts Clinical cancer research : an official journal of the American Association for Cancer Research, 2003; 9(13): 4992-9.
Sharma Sherven, Huang Min, Dohadwala Mariam, Pold Mehis, Batra Raj K, Dubinett Steven M   Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer Methods in molecular medicine, 2003; 75(3): 723-36.
Dubinett Steven M, Sharma Sherven, Huang Min, Dohadwala Mariam, Pold Mehis, Mao Jenny T   Cyclooxygenase-2 in lung cancer Progress in experimental tumor research, 2003; 37(3): 138-62.
Hillinger Sven, Yang Seok-Chul, Zhu Li, Huang Min, Duckett Russell, Atianzar Kimberly, Batra Raj K, Strieter Robert M, Dubinett Steven M, Sharma Sherven   EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model Journal of immunology (Baltimore, Md. : 1950), 2003; 171(12): 6457-65.
Zhu Li X, Sharma Sherven, Gardner Brian, Escuadro Brian, Atianzar Kimberly, Tashkin Donald P, Dubinett Steven M   IL-10 mediates sigma 1 receptor-dependent suppression of antitumor immunity Journal of immunology (Baltimore, Md. : 1950), 2003; 170(7): 3585-91.
Batra Raj K, Bernal Raymond M, Sharma Sherven   Identifying obstacles to viral gene therapy for lung cancer. Malignant pleural effusions as a paradigm Methods in molecular medicine, 2003; 75(3): 545-59.
Sharma Sherven, Batra Raj K, Yang Seok Chul, Hillinger Sven, Zhu Li, Atianzar Kimberly, Strieter Robert M, Riedl Karen, Huang Min, Dubinett Steven M   Interleukin-7 gene-modified dendritic cells reduce pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma Human gene therapy, 2003; 14(16): 1511-24.
Sharma Sherven, Yang Seok Chul, Batra Raj K, Dubinett Steven M   Intratumoral therapy with cytokine gene-modified dendritic cells in murine lung cancer models Methods in molecular medicine, 2003; 75(3): 711-22.
Gardner Brian, Zhu Li X, Sharma Sherven, Tashkin Donald P, Dubinett Steven M   Methanandamide increases COX-2 expression and tumor growth in murine lung cancer FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003; 17(14): 2157-9.
Batra Raj K, Lin Ying, Sharma Sherven, Dohadwala Mariam, Luo Jie, Pold Mehis, Dubinett Steven M   Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism Cancer research, 2003; 63(3): 642-6.
Zhang Ling, Sharma Sherven, Zhu Li X, Kogai Takahiko, Hershman Jerome M, Brent Gregory A, Dubinett Steven M, Huang Min   Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells Cancer research, 2003; 63(16): 5065-72.
Riedl Karen, Baratelli Felicita, Batra Raj K, Yang Seok Chul, Luo Jie, Escuadro Brian, Figlin Robert, Strieter Robert, Sharma Sherven, Dubinett Steven   Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells Molecular cancer, 2003; 2(12): 35.
Sharma Sherven, Yang Seok-Chul, Hillinger Sven, Zhu Li X, Huang Min, Batra Raj K, Lin Jeff F, Burdick Marie D, Strieter Robert M, Dubinett Steven M   SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10 Molecular cancer, 2003; 2(16): 22.
Sharma Sherven, Stolina Marina, Yang Seok-Chul, Baratelli Felicita, Lin Jeff F, Atianzar Kimberly, Luo Jie, Zhu Li, Lin Ying, Huang Min, Dohadwala Mariam, Batra Raj K, Dubinett Steven M   Tumor cyclooxygenase 2-dependent suppression of dendritic cell function Clinical cancer research : an official journal of the American Association for Cancer Research, 2003; 9(3): 961-8.
Gardner Brian, Zu Li X, Sharma Sherven, Liu Qian, Makriyannis Alexandros, Tashkin Donald P, Dubinett Steven M   Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta Biochemical and biophysical research communications, 2002; 290(1): 91-6.
Dohadwala Mariam, Batra Raj K, Luo Jie, Lin Ying, Krysan Kostyantyn, Pold Mehis, Sharma Sherven, Dubinett Steven M   Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion The Journal of biological chemistry, 2002; 277(52): 50828-33.
Huang Min, Sharma Sherven, Zhu Li X, Keane Michael P, Luo Jie, Zhang Ling, Burdick Marie D, Lin Ying Q, Dohadwala Mariam, Gardner Brian, Batra Raj K, Strieter Robert M, Dubinett Steven M   IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis The Journal of clinical investigation, 2002; 109(7): 931-7.
Basak Saroj K, Harui Airi, Stolina Marina, Sharma Sherven, Mitani Kohnosuke, Dubinett Steven M, Roth Michael D   Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage-colony-stimulating factor and interleukin-4 Blood, 2002; 99(8): 2869-79.
Bernal Ray M, Sharma Sherven, Gardner Brian K, Douglas Joanne T, Bergelson Jeffrey M, Dubinett Steven M, Batra Raj K   Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu Clinical cancer research : an official journal of the American Association for Cancer Research, 2002; 8(6): 1915-23.

Does this profile need updating? Contact Us