A Short Biography:
Dr. Seidlits research focuses on developing regenerative therapies for the central nervous system (CNS). Although the CNS has the innate capacity for repair, disease or injury invokes an inflammatory response that transforms the local tissue into an environment that lacks sufficient regenerative factors and contains an abundance of inhibitory factors. Dr. Seidlits laboratory aims to identify differences between the extracellular environment in injured and healthy CNS tissues and to exploit these mechanistic discoveries to develop novel, regenerative therapies that act by directly altering the local environment. To accomplish this, modular design of biomaterial microenvironments is combined with other quantitative, engineering approaches, such as high-throughput measurements, single cell analyses and genetic manipulation, to enable mechanistic discoveries that lead to the development of innovative translational therapies.
A selected list of publications:
Kijanka Gregor, Barry Richard, Chen Hong, Gould Edith, Seidlits Stephanie K, Schmid Jasmin, Morgan Maria, Mason David Y, Cordell Jacqueline, Murphy Derek
Defining the molecular target of an antibody derived from nuclear
extract of Jurkat cells using protein arrays