David Wong, D.M.D., D.M.Sc.

A Short Biography:

David T.W. Wong DMD, DMSc is Felix & Mildred Yip Endowed Professor, Associate Dean of Research and Director of the Oral/Head and Neck Oncology Research Center at UCLA. Dr. Wong is an active scientist in oral cancer and saliva diagnostics research. He has authored over 280 peer reviewed scientific publications. He is a fellow of the American Association for the Advancement of Sciences (AAAS), past member of the ADA Council of Scientific Affairs and the past president of American Association of Dental Research (AADR). 


Work Titles
CTSI Member, CTSI
UCLA Director, Dental Research Institute Director and Principal Investigator, Center for Oral/Head & Neck Oncology Research Felix & Mildred Yip Endowed Professor, Dentistry Professor, Bioengineering Professor, Head and Neck Surgery Associate Dean for Research, Dentistry Member, JCCC Cancer and Stem Cell Biology Program Area Member, JCCC Signal Transduction and Therapeutics Program Area
Education:
Degrees:
D.M.D.
D.M.Sc., Harvard
Fellowship:
2010 American College of Dentists, Fellow
1982 Medical Research Council of Canada, Post-doctoral Research Fellowship
1981 American Dental Association, The Henry M. Thorton Fellowship
Academic Experience:
2008 Oregon Health & Science University, OCTRI Academy Visiting Professorship
Honors and Awards:
SCADA, The Alan J. Davis/SCADA Achievement Award
2011 The Forsyth Institute, Dr. Murray J. Gavel Clinical Research Award
2007 International Association of Dental Research, Saliva Researcher of the Year
2004 University of California at Los Angeles, School of Dentistry, Distinguished Faculty Award
2002 IADR Experimental Pathology & Medicine Research Award, Distinguished Scientist Award
2001 Columbia University, Frederick Birnberg Research Award
1999 American Student Dental Association, 25 Dental Visionaries
1993 Harvard School of Dental Medicine, Distinguished Faculty Award
1991 National Institute of Dental Research, Research Career Development Award
1988 National Institutes of Health, FIRST Award
1987 American Cancer Society, Cancer Research Scholar Award
1985 Harvard School of Dental Medicine, The James H. Shaw Award
1981 University of British Columbia, Roy Sofield Memorial Prize in Dentistry
1980 - University of British Columbia, Dr. Lorin O. Lind Memorial Scholarship
1979 - Simon Fraser University, Chemistry Book Award
1977 American Chemical Society, Undergraduate Award in Analytical Chemistry
Certifications:
Certification Type:
2010 Sigma Xi, George Bugliarello Prize (Best paper in American Scientist "Salivary Diagnostics", 2008 and 2009)
Certification Type:
2010 American Association for Dental Research, President
2008 American Association for Dental Research, Vice President
2007 American Academy of Oral Medicine, Honorary Membership
1981 Omicron Kappa Upsilon Dental Society

Contact Information:

Work Phone Number:

(310) 206-3048

Laboratory Address:

Center for Oral/Head & Neck Oncology Research
10833 Le Conte Avenue, 73-017 CHS
Los Angeles, CA 90095


Mailing Address:

Mailing Address
10833 Le Conte Avenue
73-017 CHS
Los Angeles, CA 90095


Detailed Biography:

David T.W. Wong DMD, DMSc is Felix & Mildred Yip Endowed Professor and Associate Dean of Research and Director of the Dental Research Institute at UCLA.  Dr. Wong also holds appointment at the Division of Head & Neck Surgery/Otolaryngology, Henry Samueli School of Engineering & Applied Sciences, Molecular Biology Institute and Jonsson Comprehensive Cancer Center.

Dr. Wong joined the ULCA faculty in 2002 after a 16-year career at Harvard University. His recruitment to UCLA is to spearhead and enhance multidisciplinary research and to promote research training and career development of scientists towards oral health research. Dr. Wong is one of the country's leading scientist in oral/head and neck cancer as well as salivary diagnostic research.

Dr. Wong is an active scientist in oral cancer and saliva diagnostics research. His research has been continuously funded by NIH since 1986. He has authored over 280 peer reviewed scientific publications. He is a fellow of the American Association for the Advancement of Sciences (AAAS), past member of the ADA Council of Scientific Affairs and the immediate past president of American Association of Dental Research (AADR).

Publications:

A selected list of publications:

Wei Fang, Yang Jieping, Wong David T W   Detection of exosomal biomarker by electric field-induced release and measurement (EFIRM) Biosensors & bioelectronics, 2013; 44: 115-21.
Matse Johannes H, Yoshizawa Janice, Wang Xiaoyan, Elashoff David, Bolsher Jan G, Veerman Enno C, Bloemena Elisabeth, Wong David T   Discovery and pre-validation of salivary extracellular microRNA biomarkers panel for the non-invasive detection of benign and malignant parotid gland tumors Clinical cancer research : an official journal of the American Association for Cancer Research, 2013; 251(5): .
Wang Cheng, Liu Xiqiang, Chen Zujian, Huang Hongzhang, Jin Yi, Kolokythas Antonia, Wang Anxun, Dai Yang, Wong David T W, Zhou Xiaofeng   Polycomb group protein EZH2-mediated E-cadherin repression promotes metastasis of oral tongue squamous cell carcinoma Molecular carcinogenesis, 2013; 52(3): 229-36.
Wong David T   Salivary diagnostics: the enabling factors for detecting oral diseases Journal of the California Dental Association, 2013; 41(2): 94-6.
Yoshizawa Janice M, Wong David T W   Salivary microRNAs and oral cancer detection Methods in molecular biology (Clifton, N.J.), 2013; 936(1): 313-24.
Ai Ji-Ye, Smith Barry, Wong David T W   Bioinformatics advances in saliva diagnostics International journal of oral science, 2012; 4(2): 85-7.
Lau Chang S, Wong David T W   Breast cancer exosome-like microvesicles and salivary gland cells interplay alters salivary gland cell-derived exosome-like microvesicles in vitro PloS one, 2012; 7(3): e33037.
Vissink Arjan, Bootsma Hendrika, Spijkervet Fred K L, Hu Shen, Wong David T, Kallenberg Cees G M   Current and future challenges in primary Sjögren's syndrome Current pharmaceutical biotechnology, 2012; 13(10): 2026-45.
Zhang Lei, Xiao Hua, Zhou Hui, Santiago Silverio, Lee Jay M, Garon Edward B, Yang Jieping, Brinkmann Ole, Yan Xinmin, Akin David, Chia David, Elashoff David, Park No-Hee, Wong David T W   Development of transcriptomic biomarker signature in human saliva to detect lung cancer Cellular and molecular life sciences : CMLS, 2012; 69(19): 3341-50.
Xiao Hua, Wong David T W   Method development for proteome stabilization in human saliva Analytica chimica acta, 2012; 722(5): 63-9.
Wei Fang, Wong David T W   Point-of-care platforms for salivary diagnostics The Chinese journal of dental research : the official journal of the Scientific Section of the Chinese Stomatological Association (CSA), 2012; 15(1): 7-15.
Elashoff David, Zhou Hui, Reiss Jean, Wang Jianghua, Xiao Hua, Henson Bradley, Hu Shen, Arellano Martha, Sinha Uttam, Le Anh, Messadi Diana, Wang Marilene, Nabili Vishad, Lingen Mark, Morris Darly, Randolph Timothy, Feng Ziding, Akin David, Kastratovic Dragana A, Chia David, Abemayor Elliot, Wong David T W   Prevalidation of salivary biomarkers for oral cancer detection Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2012; 21(4): 664-72.
Xiao Hua, Zhang Lei, Zhou Hui, Lee Jay M, Garon Edward B, Wong David T W   Proteomic analysis of human saliva from lung cancer patients using two-dimensional difference gel electrophoresis and mass spectrometry Molecular & cellular proteomics : MCP, 2012; 11(2): M111.012112.
Xiao Hua, Wong David T W   Proteomic analysis of microvesicles in human saliva by gel electrophoresis with liquid chromatography-mass spectrometry Analytica chimica acta, 2012; 723(5): 61-7.
Wong David T W   Salivaomics Journal of the American Dental Association (1939), 2012; 143(10 Suppl): 19S-24S.
Bonne Nicolai J, Wong David Tw   Salivary biomarker development using genomic, proteomic and metabolomic approaches Genome medicine, 2012; 4(10): 82.
Brinkmann Ole, Spielmann Nadine, Wong David T W   Salivary diagnostics: moving to the next level Dentistry today, 2012; 31(6): 54, 56-7; quiz 58-9.
Horvath Steve, Nazmul-Hossain Abu Nm, Pollard Rodney Pe, Kroese Frans Gm, Vissink Arjan, Kallenberg Cees Gm, Spijkervet Fred Kl, Bootsma Hendrika, Michie Sara A, Gorr Sven U, Peck Ammon B, Cai Chaochao, Zhou Hui, Wong David Tw   Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model Arthritis research & therapy, 2012; 14(6): R238.
Gorr Sven-Ulrik, Wennblom Trevor J, Horvath Steve, Wong David T W, Michie Sara A   Text-mining applied to autoimmune disease research: the Sjögren's syndrome knowledge base BMC musculoskeletal disorders, 2012; 13(13): 119.
Spielmann Nadine, Ilsley Diane, Gu Jian, Lea Kristi, Brockman Joel, Heater Sheila, Setterquist Robert, Wong David T W   The human salivary RNA transcriptome revealed by massively parallel sequencing Clinical chemistry, 2012; 58(9): 1314-21.
Kim Jeong Kyu, Zhou Hui, Nabili Vishad, Wang Marilene B, Abemayor Elliot, Wong David T W   Utility of multiple sampling in reducing variation of salivary interleukin-8 and interleukin-1β mRNA levels in healthy adults Head & neck, 2012; 12(8): .
Farrell James J, Zhang Lei, Zhou Hui, Chia David, Elashoff David, Akin David, Paster Bruce J, Joshipura Kaumudi, Wong David T W   Variations of oral microbiota are associated with pancreatic diseases including pancreatic cancer Gut, 2012; 61(4): 582-8.
Lee Yu-Hsiang, Zhou Hui, Reiss Jean K, Yan Xinmin, Zhang Lei, Chia David, Wong David T W   Direct saliva transcriptome analysis Clinical chemistry, 2011; 57(9): 1295-302.
Sharma Sanjai, Liao Wei, Zhou Xiaofeng, Wong David T W, Lichtenstein Alan   Exon 11 skipping of E-cadherin RNA downregulates its expression in head and neck cancer cells Molecular cancer therapeutics, 2011; 10(9): 1751-9.
Hu Shen, Vissink Arjan, Arellano Martha, Roozendaal Caroline, Zhou Hui, Kallenberg Cees G M, Wong David T   Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays Proteomics, 2011; 11(8): 1499-507.
Brinkmann Ole, Kastratovic Dragana A, Dimitrijevic Milovan V, Konstantinovic Vitomir S, Jelovac Drago B, Antic Jadranka, Nesic Vladimir S, Markovic Srdjan Z, Martinovic Zeljko R, Akin David, Spielmann Nadine, Zhou Hui, Wong David T   Oral squamous cell carcinoma detection by salivary biomarkers in a Serbian population Oral oncology, 2011; 47(1): 51-5.
Sugimoto Masahiro, Wong David T, Hirayama Akiyoshi, Soga Tomoyoshi, Tomita Masaru   Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles Metabolomics : Official journal of the Metabolomic Society, 2010; 6(1): 78-95.
Ryan Christopher M, Souda Puneet, Halgand Frederic, Wong David T, Loo Joseph A, Faull Kym F, Whitelegge Julian P   Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry Journal of the American Society for Mass Spectrometry, 2010; 21(6): 908-17.
Williams Chloe J, Lui Wing Chi, Li Kenneth K W, Wong David, Lo Amy C Y   Correspondence Retina (Philadelphia, Pa.), 2010; 30(3): 534-5; author reply 535-6.
Zhang Lei, Xiao Hua, Karlan Scott, Zhou Hui, Gross Jenny, Elashoff David, Akin David, Yan Xinmin, Chia David, Karlan Beth, Wong David T   Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer PloS one, 2010; 5(12): e15573.
Halgand Frédéric, Zabrouskov Vlad, Bassilian Sara, Souda Puneet, Wong David T, Loo Joseph A, Faull Kym F, Whitelegge Julian P   Micro-heterogeneity of human saliva Peptide P-C characterized by high-resolution top-down Fourier-transform mass spectrometry Journal of the American Society for Mass Spectrometry, 2010; 21(5): 868-77.
Hu Shen, Gao Kai, Pollard Rodney, Arellano-Garcia Martha, Zhou Hui, Zhang Lei, Elashoff David, Kallenberg Cees G M, Vissink Arjan, Wong David T   Preclinical validation of salivary biomarkers for primary Sjögren's syndrome Arthritis care & research, 2010; 62(11): 1633-8.
Hu Shen, Jiang Jiang, Wong David T   Proteomic analysis of saliva: 2D gel electrophoresis, LC-MS/MS, and Western blotting Methods in molecular biology (Clifton, N.J.), 2010; 666(1): 31-41.
Ai Jiye, Smith Barry, Wong David T   Saliva Ontology: an ontology-based framework for a Salivaomics Knowledge Base BMC bioinformatics, 2010; 11(7): 302.
Zhang Lei, Farrell James J, Zhou Hui, Elashoff David, Akin David, Park No-Hee, Chia David, Wong David T   Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer Gastroenterology, 2010; 138(3): 949-57.e1-7.
Sharma Shivani, Rasool Haider I, Palanisamy Viswanathan, Mathisen Cliff, Schmidt Michael, Wong David T, Gimzewski James K   Structural-mechanical characterization of nanoparticle exosomes in human saliva, using correlative AFM, FESEM, and force spectroscopy ACS nano, 2010; 4(4): 1921-6.
Deshpande, Dai, Kim, Kim, Kimlin, Gao, Hendrich, Wong   CDK2AP1 is required for epigenetic silencing of OCT4 during murine embryonic stem cell differentiation The Journal of biological chemistry, 2008; .
Wei Fang, Wang Jianghua, Liao Wei, Zimmermann Bernhard G, Wong David T, Ho Chih-Ming   Electrochemical detection of low-copy number salivary RNA based on specific signal amplification with a hairpin probe Nucleic acids research, 2008; 36(11): e65.
Hu Zhanzhi, Zimmermann Bernhard G, Zhou Hui, Wang Jianghua, Henson Bradley S, Yu Weixia, Elashoff David, Krupp Guido, Wong David T   Exon-level expression profiling: a comprehensive transcriptome analysis of oral fluids Clinical chemistry, 2008; 54(5): 824-32.
Deshpande Amit M, Wong David T   Molecular mechanisms of head and neck cancer Expert review of anticancer therapy, 2008; 8(5): 799-809.
Tan Winny, Sabet Leyla, Li Yang, Yu Tianwei, Klokkevold Perry R, Wong David T, Ho Chih-Ming   Optical protein sensor for detecting cancer markers in saliva Biosensors & bioelectronics, 2008; 24(2): 266-71.
Wong, D.T.   Saliva Diagnostics, American Scientist, 2008; .
Zimmermann Bernhard G, Wong David T   Salivary mRNA targets for cancer diagnostics Oral oncology, 2008; 44(5): 425-9.
Hu Shen, Arellano Martha, Boontheung Pinmanee, Wang Jianghua, Zhou Hui, Jiang Jiang, Elashoff David, Wei Roger, Loo Joseph A, Wong David T   Salivary proteomics for oral cancer biomarker discovery Clinical cancer research : an official journal of the American Association for Cancer Research, 2008; 14(19): 6246-52.
Hu, Zhou, Jiang, Wang, Elashoff, Gorr, Michie, Spijkervet, Bootsma, Kallenberg, Vissink, Horvath, Wong   Systems biology analysis of sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands Arthritis and rheumatism, 2008; 60(1): 81-92.
Denny Paul, Hagen Fred K, Hardt Markus, Liao Lujian, Yan Weihong, Arellanno Martha, Bassilian Sara, Bedi Gurrinder S, Boontheung Pinmannee, Cociorva Daniel, Delahunty Claire M, Denny Trish, Dunsmore Jason, Faull Kym F, Gilligan Joyce, Gonzalez-Begne Mireya, Halgand Frédéric, Hall Steven C, Han Xuemei, Henson Bradley, Hewel Johannes, Hu Shen, Jeffrey Sherry, Jiang Jiang, Loo Joseph A, Ogorzalek Loo Rachel R, Malamud Daniel, Melvin James E, Miroshnychenko Olga, Navazesh Mahvash, Niles Richard, Park Sung Kyu, Prakobphol Akraporn, Ramachandran Prasanna, Richert Megan, Robinson Sarah, Sondej Melissa, Souda Puneet, Sullivan Mark A, Takashima Jona, Than Shawn, Wang Jianghua, Whitelegge Julian P, Witkowska H Ewa, Wolinsky Lawrence, Xie Yongming, Xu Tao, Yu Weixia, Ytterberg Jimmy, Wong David T, Yates John R, Fisher Susan J   The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions Journal of proteome research, 2008; 7(5): 1994-2006.
Ye Hui, Yu Tianwei, Temam Stephane, Ziober Barry L, Wang Jianguang, Schwartz Joel L, Mao Li, Wong David T, Zhou Xiaofeng   Transcriptomic dissection of tongue squamous cell carcinoma BMC genomics, 2008; 9(3): 69.
Yu, T. Ye, H. Sun, W. Li, K. C. Chen, Z. Jacobs, S. Bailey, D. K. Wong, D. T. Zhou, X.   A forward-backward fragment assembling algorithm for the identification of genomic amplification and deletion breakpoints using high-density single nucleotide polymorphism (SNP) array, BMC Bioinformatics, 2007; 8(1): 145.
Park, N. J. Zhou, X. Yu, T. Brinkman, B. M. Zimmermann, B. G. Palanisamy, V. Wong, D. T.   Characterization of salivary RNA by cDNA library analysis, Arch Oral Biol, 2007; 52: 30-35.
Hu Shen, Yu Tianwei, Xie Yongming, Yang Yanan, Li Yang, Zhou Xiaofeng, Tsung Stephanie, Loo Rachel R, Loo Joseph R, Wong David T   Discovery of oral fluid biomarkers for human oral cancer by mass spectrometry Cancer genomics & proteomics, 2007; 4(2): 55-64.
Molinolo Alfredo A, Hewitt Stephen M, Amornphimoltham Panomwat, Keelawat Somboon, Rangdaeng Samraeung, Meneses García Abelardo, Raimondi Ana R, Jufe Rafael, Itoiz María, Gao Yan, Saranath Dhananjaya, Kaleebi George S, Yoo George H, Leak Lee, Myers Ernest M, Shintani Satoru, Wong David, Massey H Davis, Yeudall W Andrew, Lonardo Fulvio, Ensley John, Gutkind J Silvio   Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative Clinical cancer research : an official journal of the American Association for Cancer Research, 2007; 13(17): 4964-73.
Ye, H. Pungpravat, N. Huang, B. L. Muzio, L. L. Mariggio, M. A. Chen, Z. Wong, D. T. Zhou, X.   Genomic assessments of the frequent loss of heterozygosity region on 8p21.3 approximately p22 in head and neck squamous cell carcinoma Cancer Genet Cytogenet, 2007; 176(2): 100-6.
Zimmermann Bernhard G, Park Noh Jin, Wong David T   Genomic targets in saliva Annals of the New York Academy of Sciences, 2007; 1098(4): 184-91.
Hu, S. Loo, J. A. Wong, D. T.   Human saliva proteome analysis and disease biomarker discovery Expert Rev Proteomics, 2007; 4(4): 531-8.
Hu Shen, Loo Joseph A, Wong David T   Human saliva proteome analysis Annals of the New York Academy of Sciences, 2007; 1098(4): 323-9.
Hu, S. Yen, Yun Ann, David Wong, D.T.   Implications of salivary proteomics for cancer drug discovery, Drug Discovery, 2007; 12: 911-916.
Hu, S. Wong, D. T.   Oral cancer proteomics Curr Opin Mol Ther, 2007; 9(5): 467-76.
Gau Vincent, Wong David   Oral fluid nanosensor test (OFNASET) with advanced electrochemical-based molecular analysis platform Annals of the New York Academy of Sciences, 2007; 1098(4): 401-10.
Whitelegge Mario A, Zabrouskov Mario A, Halgand Mario A, Souda Mario A, Bassilian Mario A, Yan Mario A, Wolinsky Mario A, Loo Mario A, Wong Mario A, Faull Mario A   Protein-Sequence Polymorphisms and Post-translational Modifications in Proteins from Human Saliva using Top-Down Fourier-transform Ion Cyclotron Resonance Mass Spectrometry International journal of mass spectrometry, 2007; 268(2-3): 190-197.
Park, N. J. Yu, T. Nabili, V. Brinkman, B. M. Henry, S. Wang, J. Wong, D. T.   RNAprotect Saliva: An Optimal Room- Temperature Stabilization Reagent for the Salivary Transcriptome Clin Chem, 2007; 52(12): 2303-4.
Zimmermann, B. G. Wong, D. T.   Salivary mRNA targets for cancer diagnostics Oral Oncol, 2007; .
Hu Shen, Wang Jianghua, Meijer Jiska, Ieong Sonya, Xie Yongming, Yu Tianwei, Zhou Hui, Henry Sharon, Vissink Arjan, Pijpe Justin, Kallenberg Cees, Elashoff David, Loo Joseph A, Wong David T   Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome Arthritis and rheumatism, 2007; 56(11): 3588-600.
Zhou X, Yu T, Cole SW, Wong DT   Advancement in characterization of genomic alterations for improved diagnosis, treatment and prognostics in cancer Expert Rev Mol Diagn, 2006; 6(1): 39-50.
Park NJ, Li Y, Yu T, Brinkman BM, Wong DT   Characterization of RNA in saliva Clin Chem, 2006; 52(6): 988-94.
Brinkman BM, Wong DT   Disease mechanism and biomarkers of oral squamous cell carcinoma Curr Opin Oncol, 2006; 18(3): 228-233.
Figueiredo ML, Dayan S, Kim Y, McBride J, Kupper TS, Wong DT   Expression of cell-cycle regulator CDK2-associating protein 1 (p12(CDK2AP1)) in transgenic mice induces testicular and ovarian atrophy in vivo Mol Reprod Dev, 2006; .
St John MA, Abemayor E, Wong DT   Recent new approaches to the treatment of head and neck cancer Anticancer Drugs, 2006; 17(4): 365-75.
Wong DT   Salivary diagnostics powered by nanotechnologies, proteomics and genomics, J American Dental Association, 2006; 137: 313-321.
Li Y, Elashoff D, Oh M, Sinha U, St John MA, Zhou X, Abemayor E, Wong DT   Serum Circulating Human mRNA Profiling and Its Utility for Oral Cancer Detection Journal Clinical Oncology, 2006; In press.
Yang CYm, Brooks E, Li Y, Denny P, Ho CM, Qi F, Shi W, Wolinsky L, Wu B, Wong DT, Montemagno CD   Detection of picomolar levels of interleukin-8 in human saliva by SPR Lab Chip, 2005; 5(10): 1017-23.
Zhou X, Jordan RC, Li Y, Huang BL, Wong DT   Frequent allelic imbalances at 8p and 11q22 in oral and oropharyngeal epithelial dysplastic lesions Cancer Genet Cytogenet, 2005; 161(1): 86-9.
Zhou X, Cole SW, Rao NP, Cheng Z, Li Y, McBride J, Wong DT   Identification of discrete chromosomal deletion by binary recursive partitioning of microarray differential expression data J Med Genet, 2005; 42(5): 416-9.
Hu S, Xie Y, Ramachandran P, Ogorzalek Loo RR, Li Y, Loo JA, Wong DT   Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry Proteomics, 2005; 5(6): 1714-28.
Zhou X, Rao NP, Cole SW, Mok SC, Chen Z, Wong DT   Progress in concurrent analysis of loss of heterozygosity and comparative genomic hybridization utilizing high density single nucleotide polymorphism arrays Cancer Genet Cytogenet, 2005; 159(1): 53-7.
Li Y, Denny P, Ho CM, Montemagno C, Shi W, Qi F, Wu B, Wolinsky L, Wong DT   The Oral Fluid MEMS/NEMS Chip (OFMNC): diagnostic and translational applications Adv Dent Res, 2005; 18(1): 3-5.
Zhou X, Jordan RCK, Mok S, Birrer MJ, Wong DT   DNA Copy Number Abnormality of Oral Squamous Cell Carcinoma Detected by cDNA, Cancer Genetics & Cytogenetics, 2004; 151: 90-92.
Zhou X, Cole SW, Hu S, Wong DT   Detection of DNA copy number abnormality by microarray expression analysis Hum Genet, 2004; 114(5): 464-467.
Hu S, Denny P, Xie Y, Loo JA, Wolinsky LE, Li Y, McBride J, Ogorzalek Loo RR, Navazesh M, Wong DT   Differentially expressed protein markers in human submandibular and sublingual secretions Int J Oncol, 2004; 25(5): 1423-30.
Shintani S, Ishikawa T, Nonaka T, Li C, Nakashiro K, Wong DT, Hamakawa H   Growth-regulated oncogene-1 expression is associated with angiogenesis and lymph node metastasis in human oral cancer Oncology, 2004; 66(4): 316-22.
St John M, Li Y, Zhou X, Denny P, Ho CM Montemagno CD, Shi W, Qi F, Wu B, Jordan RCK, Sinha U, Park NH Abemayor E, Wong DTW   IL-6 and IL-8: Potential biomarkers for oral cavity and oropharyngeal SCCA, Arch Otolaryngol Head Neck Surg, 2004; 130: 929-935.
Buajeeb W, Zhang X, Ohyam H, Han D, Surarita R, Kim Y, Wong DTW   Interaction of the CDK2 associated protein-1, p12DOC-1/CDK2AP1, with its homolog, p14DOC-1R, Biochem Biophys Res Comm, 2004; 315: 998-1003.
Figueiredo ML, Kim YK, Zhou XZ, Myers JN, Wong DDT   Molecular Mechanisms of Head and Neck Cancer, Mechanism of Diseases, 2004; 1: 273-281.
Kreth JK, Hagerman E, Tam K, Merritt J, Wong D, Wu B M, Myung NV, Shi W, Qi F   Quantitative Analyses of Streptococcus mutans Biofilms Formed under Different Sucrose Concentrations by using quartz crystal microbalance and microjet impingement, Biofilm, 2004; 1: 277-284.
Li Y, Zhou X, St John MA, Wong DT   RNA Profiling of Cell-free Saliva Using Microarray Technology J Dent Res, 2004; 83(3): 199-203.
Zhou X, Li C, Mok S, Chen Z, Wong DTW   Whole Genome LOH Profiling on Oral Squamous Cell Carcinoma by High-Density SNP Array, Cancer Genet & Cytogenet, 2004; 151: 82-84.
Majem Blanca, Li Feng, Sun Jie, Wong David T W   RNA Sequencing Analysis of Salivary Extracellular RNA Methods in molecular biology (Clifton, N.J.), 2017; 1537(1): 17-36.
Kaczor-Urbanowicz Karolina Elżbieta, Martin Carreras-Presas Carmen, Aro Katri, Tu Michael, Garcia-Godoy Franklin, Wong David Tw   Saliva diagnostics - Current views and directions Experimental biology and medicine (Maywood, N.J.), 2017; 242(5): 459-472.
Pu Dan, Liang Hao, Wei Fang, Akin David, Feng Ziding, Yan QingXiang, Li Yin, Zhen Yan, Xu Lin, Dong Gaochao, Wan Huajing, Dong Jingsi, Qiu Xiaoming, Qin Changlong, Zhu Daxing, Wang Xi, Sun Tong, Zhang Wenbiao, Li Canjun, Tang Xiaojun, Qiao Youlin, Wong David T W, Zhou Qinghua   Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study Thoracic cancer, 2016; 7(4): 428-36.
Katsiougiannis Stergios, Chia David, Kim Yong, Singh Ram P, Wong David T W   Saliva exosomes from pancreatic tumor-bearing mice modulate NK cell phenotype and antitumor cytotoxicity FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2017; 31(3): 998-1010.
Chai Yang D, Zhang Lifeng, Yang Yan, Su Trent, Charugundla Prashant, Ai Jiye, Messadi Diana, Wong David T, Hu Shen   Discovery of potential serum protein biomarkers for lymph node metastasis in oral cancer Head & neck, 2016; 38(1): 118-25.
Tu Michael, Chia David, Wei Fang, Wong David   Liquid biopsy for detection of actionable oncogenic mutations in human cancers and electric field induced release and measurement liquid biopsy (eLB) The Analyst, 2016; 141(2): 393-402.
Gleber-Netto Frederico Omar, Yakob Maha, Li Feng, Feng Ziding, Dai Jianliang, Kao Huang-Kai, Chang Yu-Liang, Chang Kai-Ping, Wong David T W   Salivary Biomarkers for Detection of Oral Squamous Cell Carcinoma in a Taiwanese Population Clinical cancer research : an official journal of the American Association for Cancer Research, 2016; 22(13): 3340-7.
Wang Austin, Wang Chris P, Tu Michael, Wong David T W   Oral Biofluid Biomarker Research: Current Status and Emerging Frontiers Diagnostics (Basel, Switzerland), 2016; 6(4): 76-79.

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