Scott G Filler, M.D.

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Work Titles
CTSI Co-Leader, Center for Translational Technologies Member, CTSI
Harbor-UCLA Medical Center Attending Physician, Harbor-UCLA Medical Center
The Lundquist Institute for Biomedical Innovation Attending Physician, INFECTIOUS DISEASES Principal Investigator, The Lundquist Institute for Biomedical Innovation
UCLA Professor In-Residence, Medicine
Education:
Degrees:
M.D., UCLA School of Medicine, Los Angeles, 1979 - 1983
A.B., Dartmouth College, 1975 - 1979
Fellowship:
1989 - 1992 Harbor-UCLA Medical Center, Torrance, CA
Internship:
1983 - 1986 Harbor-UCLA Medical Center, Torrance, CA
Residency:
1983 - 1986 Harbor-UCLA Medical Center, Torrance, CA

Contact Information:

Email Address:

sfiller@ucla.edu


Website:

http://people.healthsciences.ucla.edu/institution/personnel?personnel_id=46596
Web-Profile

Fax Number:

(310) 782-2016

Work Phone Number:

310 222-6426

Mailing Address:

Harbor-UCLA Medl Cntr-Inf Dis
1124 West Carson Street
Torrance, CA 90509


Work Address:

Laboratory
RB-2
Los Angeles, CA 90095


Publications:

A selected list of publications:

Jung Sook-In, Finkel Jonathan S, Solis Norma V, Chaili Siyang, Mitchell Aaron P, Yeaman Michael R, Filler Scott G   Bcr1 functions downstream of Ssd1 to mediate antimicrobial peptide resistance in Candida albicans Eukaryotic cell, 2013; 12(3): 411-9.
Luo Guanpingsheng, Gebremariam Teclegiorgis, Lee Hongkyu, French Samuel W, Wiederhold Nathan P, Patterson Thomas F, Filler Scott G, Ibrahim Ashraf S   Efficacy of Liposomal Amphotericin B and Posaconazole in Intratracheal Models of Murine Mucormycosis Antimicrobial agents and chemotherapy, 2013; .
Chooi Yit-Heng, Fang Jinxu, Liu Hong, Filler Scott G, Wang Pin, Tang Yi   Genome mining of a prenylated and immunosuppressive polyketide from pathogenic fungi Organic letters, 2013; 15(4): 780-3.
Fu Yue, Phan Quynh T, Luo Guanpingsheng, Solis Norma V, Liu Yaoping, Cormack Brendan P, Edwards John E, Ibrahim Ashraf S, Filler Scott G   Investigation of the Function of Candida albicans Als3 by Heterologous Expression in Candida glabrata Infection and immunity, 2013; .
Desai Jigar V, Bruno Vincent M, Ganguly Shantanu, Stamper Ronald J, Mitchell Kaitlin F, Solis Norma, Hill Elizabeth M, Xu Wenjie, Filler Scott G, Andes David R, Fanning Saranna, Lanni Frederick, Mitchell Aaron P   Regulatory Role of Glycerol in Candida albicans Biofilm Formation mBio, 2013; 4(2): .
Ariyachet Chaiyaboot, Solis Norma V, Liu Yaoping, Prasadarao Nemani V, Filler Scott G, McBride Anne E   SR-like RNA-binding protein Slr1 affects Candida albicans filamentation and virulence Infection and immunity, 2013; 81(4): 1267-76.
Seidl Kati, Solis Norma V, Bayer Arnold S, Hady Wessam Abdel, Ellison Steven, Klashman Meredith C, Xiong Yan Q, Filler Scott G   Divergent responses of different endothelial cell types to infection with Candida albicans and Staphylococcus aureus PloS one, 2012; 7(6): e39633.
Fanning Saranna, Xu Wenjie, Solis Norma, Woolford Carol A, Filler Scott G, Mitchell Aaron P   Divergent targets of Candida albicans biofilm regulator Bcr1 in vitro and in vivo Eukaryotic cell, 2012; .
Zhu Weidong, Phan Quynh T, Boontheung Pinmanee, Solis Norma V, Loo Joseph A, Filler Scott G   EGFR and HER2 receptor kinase signaling mediate epithelial cell invasion by Candida albicans during oropharyngeal infection Proceedings of the National Academy of Sciences of the United States of America, 2012; 109(35): 14194-9.
Filler Scott G   Insights from human studies into the host defense against candidiasis Cytokine, 2012; 58(1): 129-32.
Solis Norma V, Filler Scott G   Mouse model of oropharyngeal candidiasis Nature protocols, 2012; 7(4): 637-42.
Schmidt Clint S, White C Jo, Ibrahim Ashraf S, Filler Scott G, Fu Yue, Yeaman Michael R, Edwards John E, Hennessey John P   NDV-3, a recombinant alum-adjuvanted vaccine for Candida and Staphylococcus aureus, is safe and immunogenic in healthy adults Vaccine, 2012; 30(52): 7594-600.
Chen Ying-Lien, Brand Alexandra, Morrison Emma L, Silao Fitz Gerald S, Bigol Ursela G, Malbas Fedelino F, Nett Jeniel E, Andes David R, Solis Norma V, Filler Scott G, Averette Anna, Heitman Joseph   Calcineurin controls drug tolerance, hyphal growth, and virulence in Candida dubliniensis Eukaryotic cell, 2011; 10(6): 803-19.
Liu Yaoping, Filler Scott G   Candida albicans Als3, a multifunctional adhesin and invasin Eukaryotic cell, 2011; 10(2): 168-73.
Filler Scott G   Editorial overview Current opinion in microbiology, 2011; 14(4): 373-4.
Seidl Kati, Bayer Arnold S, McKinnell James A, Ellison Steven, Filler Scott G, Xiong Yan Q   In vitro endothelial cell damage is positively correlated with enhanced virulence and poor vancomycin responsiveness in experimental endocarditis due to methicillin-resistant Staphylococcus aureus Cellular microbiology, 2011; 13(10): 1530-41.
Liu Yaoping, Mittal Rahul, Solis Norma V, Prasadarao Nemani V, Filler Scott G   Mechanisms of Candida albicans trafficking to the brain PLoS pathogens, 2011; 7(10): e1002305.
Peltz Gary, Zaas Aimee K, Zheng Ming, Solis Norma V, Zhang Mason X, Liu Hong-Hsing, Hu Yajing, Boxx Gayle M, Phan Quynh T, Dill David, Filler Scott G   Next-generation computational genetic analysis: multiple complement alleles control survival after Candida albicans infection Infection and immunity, 2011; 79(11): 4472-9.
Liu Hong, Gravelat Fabrice N, Chiang Lisa Y, Chen Dan, Vanier Ghyslaine, Ejzykowicz Daniele E, Ibrahim Ashraf S, Nierman William C, Sheppard Donald C, Filler Scott G   Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis Molecular microbiology, 2010; 78(4): 1038-54.
Gravelat Fabrice N, Ejzykowicz Daniele E, Chiang Lisa Y, Chabot Josée C, Urb Mirjam, Macdonald K Denyese, al-Bader Nadia, Filler Scott G, Sheppard Donald C   Aspergillus fumigatus MedA governs adherence, host cell interactions and virulence Cellular microbiology, 2010; 12(4): 473-88.
Reedy Jennifer L, Filler Scott G, Heitman Joseph   Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence Fungal genetics and biology : FG & B, 2010; 47(2): 107-16.
Sun Jianing N, Solis Norma V, Phan Quynh T, Bajwa Jashanjot S, Kashleva Helena, Thompson Angela, Liu Yaoping, Dongari-Bagtzoglou Anna, Edgerton Mira, Filler Scott G   Host cell invasion and virulence mediated by Candida albicans Ssa1 PLoS pathogens, 2010; 6(11): e1001181.
Niemann James T, Youngquist Scott, Rosborough John P, Shah Atman P, Phan Quynh T, Filler Scott G   Infliximab attenuates early myocardial dysfunction after resuscitation in a swine cardiac arrest model Critical care medicine, 2010; 38(4): 1162-7.
Zhu Weidong, Filler Scott G   Interactions of Candida albicans with epithelial cells Cellular microbiology, 2010; 12(3): 273-82.
Ejzykowicz Daniele E, Solis Norma V, Gravelat Fabrice N, Chabot Josee, Li Xuexian, Sheppard Donald C, Filler Scott G   Role of Aspergillus fumigatus DvrA in host cell interactions and virulence Eukaryotic cell, 2010; 9(10): 1432-40.
Al-Bader Nadia, Vanier Ghyslaine, Liu Hong, Gravelat Fabrice N, Urb Mirjam, Hoareau Christopher M-Q, Campoli Paolo, Chabot Joseé, Filler Scott G, Sheppard Donald C   Role of trehalose biosynthesis in Aspergillus fumigatus development, stress response, and virulence Infection and immunity, 2010; 78(7): 3007-18.
Liu Mingfu, Spellberg Brad, Phan Quynh T, Fu Yue, Fu Yong, Lee Amy S, Edwards John E, Filler Scott G, Ibrahim Ashraf S   The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice The Journal of clinical investigation, 2010; 120(6): 1914-24.
Pappas Peter G, Chetchotisakd Ploenchan, Larsen Robert A, Manosuthi Weerawat, Morris Michele I, Anekthananon Thomansak, Sungkanuparph Somnuek, Supparatpinyo Khauncahi, Nolen Tracy L, Zimmer Louise O, Kendrick Amy S, Johnson Phillip, Sobel Jack D, Filler Scott G   A phase II randomized trial of amphotericin B alone or combined with fluconazole in the treatment of HIV-associated cryptococcal meningitis Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009; 48(12): 1775-83.
Elson Sarah L, Noble Suzanne M, Solis Norma V, Filler Scott G, Johnson Alexander D   An RNA transport system in Candida albicans regulates hyphal morphology and invasive growth PLoS genetics, 2009; 5(9): e1000664.
Moreno-Ruiz Emilia, Galán-Díez Marta, Zhu Weidong, Fernández-Ruiz Elena, d'Enfert Christophe, Filler Scott G, Cossart Pascale, Veiga Esteban   Candida albicans internalization by host cells is mediated by a clathrin-dependent mechanism Cellular microbiology, 2009; 11(8): 1179-89.
Niemann James T, Rosborough John P, Youngquist Scott, Shah Atman P, Lewis Roger J, Phan Quynh T, Filler Scott G   Cardiac function and the proinflammatory cytokine response after recovery from cardiac arrest in swine Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2009; 29(11): 749-58.
Pappas Peter G, Kauffman Carol A, Andes David, Benjamin Daniel K, Calandra Thierry F, Edwards John E, Filler Scott G, Fisher John F, Kullberg Bart-Jan, Ostrosky-Zeichner Luis, Reboli Annette C, Rex John H, Walsh Thomas J, Sobel Jack D, Sobel Jack D   Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009; 48(5): 503-35.
Sungkanuparph Somnuek, Filler Scott G, Chetchotisakd Ploenchan, Pappas Peter G, Nolen Tracy L, Manosuthi Weerawat, Anekthananon Thanomsak, Morris Michele I, Supparatpinyo Khuanchai, Kopetskie Heather, Kendrick Amy S, Johnson Philip C, Sobel Jack D, Larsen Robert A   Cryptococcal immune reconstitution inflammatory syndrome after antiretroviral therapy in AIDS patients with cryptococcal meningitis: a prospective multicenter study Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009; 49(6): 931-4.
Manosuthi Weerawat, Sungkanuparph Somnuek, Anekthananon Thanomsak, Supparatpinyo Khuanchai, Nolen Tracy L, Zimmer Louise O, Pappas Peter G, Larsen Robert A, Filler Scott G, Chetchotisakd Ploenchan, Chetchotisakd Ploenchan   Effect of high-dose fluconazole on QT interval in patients with human immunodeficiency virus (HIV)-associated cryptococcal meningitis International journal of antimicrobial agents, 2009; 34(5): 494-6.
Phan Quynh T, Filler Scott G   Endothelial cell stimulation by Candida albicans Methods in molecular biology (Clifton, N.J.), 2009; 470(1): 313-26.
Kamai Yasuki, Lossinsky Albert S, Liu Hong, Sheppard Donald C, Filler Scott G   Polarized response of endothelial cells to invasion by Aspergillus fumigatus Cellular microbiology, 2009; 11(1): 170-82.
Conti Heather R, Shen Fang, Nayyar Namrata, Stocum Eileen, Sun Jianing N, Lindemann Matthew J, Ho Allen W, Hai Justine Hoda, Yu Jeffrey J, Jung Ji Won, Filler Scott G, Masso-Welch Patricia, Edgerton Mira, Gaffen Sarah L   Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis The Journal of experimental medicine, 2009; 206(2): 299-311.
Ejzykowicz Daniele E, Cunha Marcel M, Rozental Sonia, Solis Norma V, Gravelat Fabrice N, Sheppard Donald C, Filler Scott G   The Aspergillus fumigatus transcription factor Ace2 governs pigment production, conidiation and virulence Molecular microbiology, 2009; 72(1): 155-69.
Park Hyunsook, Liu Yaoping, Solis Norma, Spotkov Joshua, Hamaker Jessica, Blankenship Jill R, Yeaman Michael R, Mitchell Aaron P, Liu Haoping, Filler Scott G   Transcriptional responses of candida albicans to epithelial and endothelial cells Eukaryotic cell, 2009; 8(10): 1498-510.
Chiang Lisa Y, Sheppard Donald C, Gravelat Fabrice N, Patterson Thomas F, Filler Scott G   Aspergillus fumigatus stimulates leukocyte adhesion molecules and cytokine production by endothelial cells in vitro and during invasive pulmonary disease Infection and immunity, 2008; 76(8): 3429-38.
Nobile Clarissa J, Solis Norma, Myers Carter L, Fay Allison J, Deneault Jean-Sebastien, Nantel Andre, Mitchell Aaron P, Filler Scott G   Candida albicans transcription factor Rim101 mediates pathogenic interactions through cell wall functions Cellular microbiology, 2008; 10(11): 2180-96.
Reed Caitlin, Bryant Richard, Ibrahim Ashraf S, Edwards John, Filler Scott G, Goldberg Robert, Spellberg Brad   Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008; 47(3): 364-71.
Nobile Clarissa J, Schneider Heather A, Nett Jeniel E, Sheppard Donald C, Filler Scott G, Andes David R, Mitchell Aaron P   Complementary adhesin function in C. albicans biofilm formation Current biology : CB, 2008; 18(14): 1017-24.
Spikes Sara, Xu Ran, Nguyen C Kim, Chamilos Georgios, Kontoyiannis Dimitrios P, Jacobson Raymond H, Ejzykowicz Daniele E, Chiang Lisa Y, Filler Scott G, May Gregory S   Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence The Journal of infectious diseases, 2008; 197(3): 479-86.
Gravelat Fabrice N, Doedt Thomas, Chiang Lisa Y, Liu Hong, Filler Scott G, Patterson Thomas F, Sheppard Donald C   In vivo analysis of Aspergillus fumigatus developmental gene expression determined by real-time reverse transcription-PCR Infection and immunity, 2008; 76(8): 3632-9.
Gank Kimberly D, Yeaman Michael R, Kojima Satoshi, Yount Nannette Y, Park Hyunsook, Edwards John E, Filler Scott G, Fu Yue   SSD1 is integral to host defense peptide resistance in Candida albicans Eukaryotic cell, 2008; 7(8): 1318-27.
Goyard Sophie, Knechtle Philipp, Chauvel Murielle, Mallet Adeline, Prévost Marie-Christine, Proux Caroline, Coppée Jean-Yves, Schwartz Patrick, Dromer Françoise, Park Hyunsook, Filler Scott G, Janbon Guilhem, d'Enfert Christophe   The Yak1 kinase is involved in the initiation and maintenance of hyphal growth in Candida albicans Molecular biology of the cell, 2008; 19(5): 2251-66.
Spellberg Brad, Ibrahim Ashraf S, Yeaman Michael R, Lin Lin, Fu Yue, Avanesian Valentina, Bayer Arnold S, Filler Scott G, Lipke Peter, Otoo Henry, Edwards John E   The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus Infection and immunity, 2008; 76(10): 4574-80.
Barker Katherine S, Park Hyunsook, Phan Quynh T, Xu Lijing, Homayouni Ramin, Rogers P David, Filler Scott G   Transcriptome profile of the vascular endothelial cell response to Candida albicans The Journal of infectious diseases, 2008; 198(2): 193-202.
Almeida Ricardo S, Brunke Sascha, Albrecht Antje, Thewes Sascha, Laue Michael, Edwards John E, Filler Scott G, Hube Bernhard   the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin PLoS pathogens, 2008; 4(11): e1000217.
Phan Quynh T, Myers Carter L, Fu Yue, Sheppard Donald C, Yeaman Michael R, Welch William H, Ibrahim Ashraf S, Edwards John E, Filler Scott G   Als3 is a Candida albicans invasin that binds to cadherins and induces endocytosis by host cells PLoS biology, 2007; 5(3): e64.
Chiang Lisa Y, Sheppard Donald C, Bruno Vincent M, Mitchell Aaron P, Edwards John E, Filler Scott G   Candida albicans protein kinase CK2 governs virulence during oropharyngeal candidiasis Cellular microbiology, 2007; 9(1): 233-45.
Thewes Sascha, Kretschmar Marianne, Park Hyunsook, Schaller Martin, Filler Scott G, Hube Bernhard   In vivo and ex vivo comparative transcriptional profiling of invasive and non-invasive Candida albicans isolates identifies genes associated with tissue invasion Molecular microbiology, 2007; 63(6): 1606-28.
Filler Scott G, Solis Norma V, Guo Jane, Doellgast George, Ruiz-Garcia Ana, Pan Wei-Jian   Pharmacokinetics of murine p75-Fc fusion protein and MP6-XT22 anti-murine TNF-alpha mAb in mice The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research, 2007; 12(1): 52-6.
Norice Carmelle T, Smith Frank J, Solis Norma, Filler Scott G, Mitchell Aaron P   Requirement for Candida albicans Sun41 in biofilm formation and virulence Eukaryotic cell, 2007; 6(11): 2046-55.
Martinez-Lopez Raquel, Park Hyunsook, Myers Carter L, Gil Concha, Filler Scott G   Candida albicans Ecm33p is important for normal cell wall architecture and interactions with host cells Eukaryotic cell, 2006; 5(1): 140-7.
Filler Scott G   Candida-host cell receptor-ligand interactions Current opinion in microbiology, 2006; 9(4): 333-9.
Nobile Clarissa J, Andes David R, Nett Jeniel E, Smith Frank J, Yue Fu, Phan Quynh-Trang, Edwards John E, Filler Scott G, Mitchell Aaron P   Critical role of Bcr1-dependent adhesins in C. albicans biofilm formation in vitro and in vivo PLoS pathogens, 2006; 2(7): e63.
Spellberg Brad J, Filler Scott G, Edwards John E   Current treatment strategies for disseminated candidiasis Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006; 42(2): 244-51.
Fowler Vance G, Boucher Helen W, Corey G Ralph, Abrutyn Elias, Karchmer Adolf W, Rupp Mark E, Levine Donald P, Chambers Henry F, Tally Francis P, Vigliani Gloria A, Cabell Christopher H, Link Arthur Stanley, DeMeyer Ignace, Filler Scott G, Zervos Marcus, Cook Paul, Parsonnet Jeffrey, Bernstein Jack M, Price Connie Savor, Forrest Graeme N, Fätkenheuer Gerd, Gareca Marcelo, Rehm Susan J, Brodt Hans Reinhardt, Tice Alan, Cosgrove Sara E, Cosgrove Sara E   Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus The New England journal of medicine, 2006; 355(7): 653-65.
Chiang Lisa Y, Ejzykowicz Daniele E, Tian Zong-Qiang, Katz Leonard, Filler Scott G   Efficacy of ambruticin analogs in a murine model of invasive pulmonary aspergillosis Antimicrobial agents and chemotherapy, 2006; 50(10): 3464-6.
Spellberg Brad J, Ibrahim Ashraf S, Avanesian Valentina, Fu Yue, Myers Carter, Phan Quynh T, Filler Scott G, Yeaman Michael R, Edwards John E   Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis The Journal of infectious diseases, 2006; 194(2): 256-60.
Filler Scott G, Sheppard Donald C   Fungal invasion of normally non-phagocytic host cells PLoS pathogens, 2006; 2(12): e129.
Kamai Y, Chiang L Y, Lopes Bezerra L M, Doedt T, Lossinsky A S, Sheppard D C, Filler S G   Interactions of Aspergillus fumigatus with vascular endothelial cells Medical mycology : official publication of the International Society for Human and Animal Mycology, 2006; 44 Suppl 1(4): S115-7.
Sheppard Donald C, Graybill John R, Najvar Laura K, Chiang Lisa Y, Doedt Thomas, Kirkpatrick William R, Bocanegra Rosie, Vallor Ana C, Patterson Thomas F, Filler Scott G   Standardization of an experimental murine model of invasive pulmonary aspergillosis Antimicrobial agents and chemotherapy, 2006; 50(10): 3501-3.
Goldman Mitchell, Cloud Gretchen A, Wade Karen D, Reboli Annette C, Fichtenbaum Carl J, Hafner Richard, Sobel Jack D, Powderly William G, Patterson Thomas F, Wheat Lawrence J, Stein David K, Dismukes William E, Filler Scott G, Filler Scott G, Filler Scott G   A randomized study of the use of fluconazole in continuous versus episodic therapy in patients with advanced HIV infection and a history of oropharyngeal candidiasis: AIDS Clinical Trials Group Study 323/Mycoses Study Group Study 40 Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005; 41(10): 1473-80.
Spellberg Brad, Ibrahim Ashraf S, Edwards John E, Filler Scott G   Mice with disseminated candidiasis die of progressive sepsis The Journal of infectious diseases, 2005; 192(2): 336-43.
Phan Quynh T, Fratti Rutillio A, Prasadarao Nemani V, Edwards John E, Filler Scott G   N-cadherin mediates endocytosis of Candida albicans by endothelial cells The Journal of biological chemistry, 2005; 280(11): 10455-61.
Park Hyunsook, Myers Carter L, Sheppard Donald C, Phan Quynh T, Sanchez Angela A, E Edwards John, Filler Scott G   Role of the fungal Ras-protein kinase A pathway in governing epithelial cell interactions during oropharyngeal candidiasis Cellular microbiology, 2005; 7(4): 499-510.
Sheppard Donald C, Doedt Thomas, Chiang Lisa Y, Kim H Stanley, Chen Dan, Nierman William C, Filler Scott G   The Aspergillus fumigatus StuA protein governs the up-regulation of a discrete transcriptional program during the acquisition of developmental competence Molecular biology of the cell, 2005; 16(12): 5866-79.
Spellberg Brad J, Ibrahim Ashraf S, Avenissian Valentina, Filler Scott G, Myers Carter L, Fu Yue, Edwards John E   The anti-Candida albicans vaccine composed of the recombinant N terminus of Als1p reduces fungal burden and improves survival in both immunocompetent and immunocompromised mice Infection and immunity, 2005; 73(9): 6191-3.
Filler Scott G, Yeaman Michael R, Sheppard Donald C   Tumor necrosis factor inhibition and invasive fungal infections Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005; 41 Suppl 3(9): S208-12.
Ibrahim Ashraf S, Spellberg Brad J, Avenissian Valentina, Fu Yue, Filler Scott G, Edwards John E   Vaccination with recombinant N-terminal domain of Als1p improves survival during murine disseminated candidiasis by enhancing cell-mediated, not humoral, immunity Infection and immunity, 2005; 73(2): 999-1005.
Dilmaghanian Shahrzad, Gerber John G, Filler Scott G, Sanchez Angela, Gal Joseph   Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates Chirality, 2004; 16(2): 79-85.
Loza Lucio, Fu Yue, Ibrahim Ashraf S, Sheppard Donald C, Filler Scott G, Edwards John E   Functional analysis of the Candida albicans ALS1 gene product Yeast (Chichester, England), 2004; 21(6): 473-82.
Sheppard Donald C, Yeaman Michael R, Welch William H, Phan Quynh T, Fu Yue, Ibrahim Ashraf S, Filler Scott G, Zhang Mason, Waring Alan J, Edwards John E   Functional and structural diversity in the Als protein family of Candida albicans The Journal of biological chemistry, 2004; 279(29): 30480-9.
Pappas Peter G, Rex John H, Sobel Jack D, Filler Scott G, Dismukes William E, Walsh Thomas J, Edwards John E, Edwards John E   Guidelines for treatment of candidiasis Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004; 38(2): 161-89.
Lopes Bezerra Leila M, Filler Scott G   Interactions of Aspergillus fumigatus with endothelial cells: internalization, injury, and stimulation of tissue factor activity Blood, 2004; 103(6): 2143-9.
Sheppard Donald C, Rieg Gunter, Chiang Lisa Y, Filler Scott G, Edwards John E, Ibrahim Ashraf S   Novel inhalational murine model of invasive pulmonary aspergillosis Antimicrobial agents and chemotherapy, 2004; 48(5): 1908-11.
Sanchez Angela A, Johnston Douglas A, Myers Carter, Edwards John E, Mitchell Aaron P, Filler Scott G   Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro Infection and immunity, 2004; 72(1): 598-601.
Blankenship Jill R, Wormley Floyd L, Boyce Molly K, Schell Wiley A, Filler Scott G, Perfect John R, Heitman Joseph   Calcineurin is essential for Candida albicans survival in serum and virulence Eukaryotic cell, 2003; 2(3): 422-30.
Fukuoka Takashi, Johnston Douglas A, Winslow Carol A, de Groot Marcel J, Burt Catherine, Hitchcock Christopher A, Filler Scott G   Genetic basis for differential activities of fluconazole and voriconazole against Candida krusei Antimicrobial agents and chemotherapy, 2003; 47(4): 1213-9.
Spellberg Brad, Johnston Douglas, Phan Quynh Trang, Edwards John E, French Samuel W, Ibrahim Ashraf S, Filler Scott G   Parenchymal organ, and not splenic, immunity correlates with host survival during disseminated candidiasis Infection and immunity, 2003; 71(10): 5756-64.
Bensen Eric S, Filler Scott G, Berman Judith   A forkhead transcription factor is important for true hyphal as well as yeast morphogenesis in Candida albicans Eukaryotic cell, 2002; 1(5): 787-98.
Fu Yue, Ibrahim Ashraf S, Sheppard Donald C, Chen Yee-Chun, French Samuel W, Cutler Jim E, Filler Scott G, Edwards John E   Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway Molecular microbiology, 2002; 44(1): 61-72.
Davis Dana A, Bruno Vincent M, Loza Lucio, Filler Scott G, Mitchell Aaron P   Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis Genetics, 2002; 162(4): 1573-81.
Cannom Rebecca R M, French Samuel W, Johnston Douglas, Edwards Jr John E, Filler Scott G   Candida albicans stimulates local expression of leukocyte adhesion molecules and cytokines in vivo The Journal of infectious diseases, 2002; 186(3): 389-96.
Kamai Yasuki, Kubota Mikie, Kamai Yoko, Hosokawa Tsunemichi, Fukuoka Takashi, Filler Scott G   Contribution of Candida albicans ALS1 to the pathogenesis of experimental oropharyngeal candidiasis Infection and immunity, 2002; 70(9): 5256-8.
Belanger Paul H, Johnston Douglas A, Fratti Rutilio A, Zhang Mason, Filler Scott G   Endocytosis of Candida albicans by vascular endothelial cells is associated with tyrosine phosphorylation of specific host cell proteins Cellular microbiology, 2002; 4(12): 805-12.
Swindells Susan, Evans Scott, Zackin Robert, Goldman Mitchell, Haubrich Richard, Filler Scott G, Balfour Henry H, Balfour Henry H   Predictive value of HIV-1 viral load on risk for opportunistic infection Journal of acquired immune deficiency syndromes (1999), 2002; 30(2): 154-8.
Oh C K, Filler S G, Cho S H   Eukaryotic translation initiation factor-6 enhances histamine and IL-2 production in mast cells Journal of immunology (Baltimore, Md. : 1950), 2001; 166(5): 3606-11.
Rex J H, Walsh T J, Sobel J D, Filler S G, Pappas P G, Dismukes W E, Edwards J E   Reply to Dr. Chandrasekar (Clin Infect Dis 2001; 32:320-1) and Drs. Marr and Boeckh (Clin Infect Dis 2001; 32:321) Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001; 32(3): 518-9.
Orozco A S, Zhou X, Filler S G   Mechanisms of the proinflammatory response of endothelial cells to Candida albicans infection Infection and immunity, 2000; 68(3): 1134-41.
Tsuchimori N, Sharkey L L, Fonzi W A, French S W, Edwards J E, Filler S G   Reduced virulence of HWP1-deficient mutants of Candida albicans and their interactions with host cells Infection and immunity, 2000; 68(4): 1997-2002.
Phan Q T, Belanger P H, Filler S G   Role of hyphal formation in interactions of Candida albicans with endothelial cells Infection and immunity, 2000; 68(6): 3485-90.
Kupferwasser L I, Yeaman M R, Shapiro S M, Nast C C, Sullam P M, Filler S G, Bayer A S   Acetylsalicylic acid reduces vegetation bacterial density, hematogenous bacterial dissemination, and frequency of embolic events in experimental Staphylococcus aureus endocarditis through antiplatelet and antibacterial effects Circulation, 1999; 99(21): 2791-7.
Rieg G, Fu Y, Ibrahim A S, Zhou X, Filler S G, Edwards J E   Unanticipated heterogeneity in growth rate and virulence among Candida albicans AAF1 null mutants Infection and immunity, 1999; 67(7): 3193-8.
Fu Y, Filler S G, Spellberg B J, Fonzi W, Ibrahim A S, Kanbe T, Ghannoum M A, Edwards J E   Cloning and characterization of CAD1/AAF1, a gene from Candida albicans that induces adherence to endothelial cells after expression in Saccharomyces cerevisiae Infection and immunity, 1998; 66(5): 2078-84.
Fu Y, Rieg G, Fonzi W A, Belanger P H, Edwards J E, Filler S G   Expression of the Candida albicans gene ALS1 in Saccharomyces cerevisiae induces adherence to endothelial and epithelial cells Infection and immunity, 1998; 66(4): 1783-6.
Orozco A S, Higginbotham L M, Hitchcock C A, Parkinson T, Falconer D, Ibrahim A S, Ghannoum M A, Filler S G   Mechanism of fluconazole resistance in Candida krusei Antimicrobial agents and chemotherapy, 1998; 42(10): 2645-9.
Ibrahim A S, Filler S G, Sanglard D, Edwards J E, Hube B   Secreted aspartyl proteinases and interactions of Candida albicans with human endothelial cells Infection and immunity, 1998; 66(6): 3003-5.

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