Srinivasa T. Reddy, Ph.D.

Work Titles
California NanoSystems Institute Member, California NanoSystems Institute
UCLA Professor In-Residence, Medicine Professor In-Residence, Obstetrics and Gynecology Professor In-Residence, Molecular & Medical Pharmacology Member, Interdepartmental Program in Molecular Toxicology Member, Molecular Biology Institute Member, Molecular Pharmacology GPB Home Area Member, Molecular, Cellular & Integrative Physiology GPB Home Area Faculty, Cardiology

Contact Information:

Work Email Address:

Lab Number:



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Laboratory Address:

A-8 122 CHS
650 Charles E. Young Drive South
Los Angeles, CA 90095

43-153 CHS

Office Address:

43-144 CHS


A selected list of publications:

Guirgis Faheem W, Dodani Sunita, Leeuwenburgh Christiaan, Moldawer Lyle, Bowman Jennifer, Kalynych Colleen, Grijalva Victor, Reddy Srinivasa T, Jones Alan E, Moore Frederick A   HDL inflammatory index correlates with and predicts severity of organ failure in patients with sepsis and septic shock PloS one, 2018; 13(9): e0203813.
Singh Rajan, Pervin Shehla, Lee Se-Jin, Kuo Alan, Grijalva Victor, David John, Vergnes Laurent, Reddy Srinivasa T   Metabolic profiling of follistatin overexpression: a novel therapeutic strategy for metabolic diseases Diabetes, metabolic syndrome and obesity : targets and therapy, 2018; 11: 65-84.
Meriwether David, Sulaiman Dawoud, Volpe Carmen, Dorfman Anna, Grijalva Victor, Dorreh Nasrin, Solorzano-Vargas R Sergio, Wang Jifang, O'Connor Ellen, Papesh Jeremy, Larauche Muriel, Trost Hannah, Palgunachari Mayakonda N, Anantharamaiah G M, Herschman Harvey R, Martin Martin G, Fogelman Alan M, Reddy Srinivasa T   Apolipoprotein A-I mimetics mitigate intestinal inflammation in COX2-dependent inflammatory bowel disease model The Journal of clinical investigation, 2019; 130(6): .
Cedó Lídia, Reddy Srinivasa T, Mato Eugènia, Blanco-Vaca Francisco, Escolà-Gil Joan Carles   HDL and LDL: Potential New Players in Breast Cancer Development Journal of clinical medicine, 2019; 8(6): .
Sulaiman Dawoud, Li Jingyuan, Devarajan Asokan, Cunningham Christine Marie, Li Min, Fishbein Gregory A, Fogelman Alan M, Eghbali Mansoureh, Reddy Srinivasa T   Paraoxonase 2 protects against acute myocardial ischemia-reperfusion injury by modulating mitochondrial function and oxidative stress via the PI3K/Akt/GSK-3β RISK pathway Journal of molecular and cellular cardiology, 2019; 129(6): 154-164.
Shih Diana M, Meng Yonghong, Sallam Tamer, Vergnes Laurent, Shu Michelle L, Reue Karen, Tontonoz Peter, Fogelman Alan M, Lusis Aldons J, Reddy Srinivasa T   PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity Antioxidants (Basel, Switzerland), 2019; 8(1): 154-164.
Mukherjee Pallavi, Hough Greg, Chattopadhyay Arnab, Grijalva Victor, O'Connor Ellen Ines, Meriwether David, Wagner Alan, Ntambi James M, Navab Mohamad, Reddy Srinivasa T, Fogelman Alan M   Role of enterocyte stearoyl-Co-A desaturase-1 in LDLR-null mice Journal of lipid research, 2018; 59(10): 1818-1840.
Charles-Schoeman C, Gugiu G B, Ge H, Shahbazian A, Lee Y Y, Wang X, Furst D E, Ranganath V K, Maldonado M, Lee Terry, Reddy S T   Remodeling of the HDL proteome with treatment response to abatacept or adalimumab in the AMPLE trial of patients with rheumatoid arthritis Atherosclerosis, 2018; 275: 107-114.
Guirgis Faheem W, Leeuwenburgh Christiaan, Grijalva Victor, Bowman Jennifer, Kalynych Colleen, Moldawer Lyle, Moore Frederick A, Reddy Srinivasa T   HDL Cholesterol Efflux is Impaired in Older Patients with Early Sepsis: A Subanalysis of a Prospective Pilot Study Shock (Augusta, Ga.), 2018; 50(1): 66-70.
Morgantini C, Trifirò S, Tricò D, Meriwether D, Baldi S, Mengozzi A, Reddy S T, Natali A   A short-term increase in dietary cholesterol and fat intake affects high-density lipoprotein composition in healthy subjects Nutrition, metabolism, and cardiovascular diseases : NMCD, 2018; 28(6): 575-581.
Li Wei, Kennedy David, Shao Zhili, Wang Xi, Kamdar Andre Klaassen, Weber Malory, Mislick Kayla, Kiefer Kathryn, Morales Rommel, Agatisa-Boyle Brendan, Shih Diana M, Reddy Srinivasa T, Moravec Christine S, Tang W H Wilson   Paraoxonase 2 prevents the development of heart failure Free radical biology & medicine, 2018; 121: 117-126.
Chattopadhyay Arnab, Yang Xinying, Mukherjee Pallavi, Sulaiman Dawoud, Fogelman Hannah R, Grijalva Victor, Dubinett Steven, Wasler Tonya C, Paul Manash K, Salehi-Rad Ramin, Mack Julia J, Iruela-Arispe M Luisa, Navab Mohamad, Fogelman Alan M, Reddy Srinivasa T   Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer Scientific reports, 2018; 8(1): 9032.
Charles-Schoeman Christina, Meriwether David, Lee Yuen Yin, Shahbazian Ani, Reddy Srinivasa T   High levels of oxidized fatty acids in HDL are associated with impaired HDL function in patients with active rheumatoid arthritis Clinical rheumatology, 2018; 37(3): 615-622.
Devarajan Asokan, Su Feng, Grijalva Victor, Yalamanchi Meghna, Yalamanchi Ashna, Gao Feng, Trost Hannah, Nwokedi Josephine, Farias-Eisner Gina, Farias-Eisner Robin, Fogelman Alan M, Reddy Srinivasa T   Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer Cell death & disease, 2018; 9(3): 392.
Guirgis Faheem W, Dodani Sunita, Moldawer Lyle, Leeuwenburgh Christiaan, Bowman Jennifer, Kalynych Colleen, Jones Alan E, Reddy Srinivasa T, Moore Frederick A   Exploring the Predictive Ability of Dysfunctional High-Density Lipoprotein for Adverse Outcomes in Emergency Department Patients with Sepsis: A Preliminary Investigation Shock (Augusta, Ga.), 2017; 48(5): 539-544.
Mukherjee Pallavi, Hough Greg, Chattopadhyay Arnab, Navab Mohamad, Fogelman Hannah R, Meriwether David, Williams Kevin, Bensinger Steven, Moller Travis, Faull Kym F, Lusis Aldons J, Iruela-Arispe M Luisa, Bostrom Kristina I, Tontonoz Peter, Reddy Srinivasa T, Fogelman Alan M   Transgenic tomatoes expressing the 6F peptide and ezetimibe prevent diet-induced increases of IFN-β and cholesterol 25-hydroxylase in jejunum Journal of lipid research, 2017; 58(8): 1636-1647.
Singh Rajan, Braga Melissa, Reddy Srinivasa T, Lee Se-Jin, Parveen Meher, Grijalva Victor, Vergnes Laurent, Pervin Shehla   Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues Endocrinology, 2017; 158(5): 1217-1230.
Charles-Schoeman Christina, Yin Lee Yuen, Shahbazian Ani, Wang Xiaoyan, Elashoff David, Curtis Jeffrey R, Navarro-Millán Iris, Yang Shuo, Chen Lang, Cofield Stacey S, Moreland Larry W, Paulus Harold, O'Dell James, Bathon Joan, Louis Bridges S, Reddy Srinivasa T   Improvement of High-Density Lipoprotein Function in Patients With Early Rheumatoid Arthritis Treated With Methotrexate Monotherapy or Combination Therapies in a Randomized Controlled Trial Arthritis & rheumatology (Hoboken, N.J.), 2017; 69(1): 46-57.
Cedó Lídia, García-León Annabel, Baila-Rueda Lucía, Santos David, Grijalva Victor, Martínez-Cignoni Melanie Raquel, Carbó José M, Metso Jari, López-Vilaró Laura, Zorzano Antonio, Valledor Annabel F, Cenarro Ana, Jauhiainen Matti, Lerma Enrique, Fogelman Alan M, Reddy Srinivasa T, Escolà-Gil Joan Carles, Blanco-Vaca Francisco   ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer Scientific reports, 2016; 6: 36387.
Sharma Salil, Ruffenach Grégoire, Umar Soban, Motayagheni Negar, Reddy Srinivasa T, Eghbali Mansoureh   Role of oxidized lipids in pulmonary arterial hypertension Pulmonary circulation, 2016; 6(3): 261-73.
Meriwether David, Sulaiman Dawoud, Wagner Alan, Grijalva Victor, Kaji Izumi, Williams Kevin J, Yu Liqing, Fogelman Spencer, Volpe Carmen, Bensinger Steven J, Anantharamaiah G M, Shechter Ishaiahu, Fogelman Alan M, Reddy Srinivasa T   Transintestinal transport of the anti-inflammatory drug 4F and the modulation of transintestinal cholesterol efflux Journal of lipid research, 2016; 57(7): 1175-93.
Mehta Niyati U, Grijalva Victor, Hama Susan, Wagner Alan, Navab Mohamad, Fogelman Alan M, Reddy Srinivasa T   Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function Arteriosclerosis, thrombosis, and vascular biology, 2016; 36(6): 1152-63.
Chattopadhyay Arnab, Navab Mohamad, Hough Greg, Grijalva Victor, Mukherjee Pallavi, Fogelman Hannah R, Hwang Lin H, Faull Kym F, Lusis Aldons J, Reddy Srinivasa T, Fogelman Alan M   Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD Journal of lipid research, 2016; 57(5): 832-47.
Sharma Salil, Umar Soban, Potus Francois, Iorga Andrea, Wong Gabriel, Meriwether David, Breuils-Bonnet Sandra, Mai Denise, Navab Kaveh, Ross David, Navab Mohamad, Provencher Steeve, Fogelman Alan M, Bonnet Sébastien, Reddy Srinivasa T, Eghbali Mansoureh   Apolipoprotein A-I mimetic peptide 4F rescues pulmonary hypertension by inducing microRNA-193-3p Circulation, 2014; 130(9): 776-85.

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