Lawrence Kruger, Ph.D.

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UCLA Emeritus Distinguished Professor , Neurobiology Emeritus Member, Brain Research Institute

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Los Angeles, CA 90095

Detailed Biography:

Pain endings and their molecular properties The principal aim of my laboratory program was focused on the characterization of visceral pain endings and the results of the final morphological (electron microscopy) studies of physiologically characterized 'nociceptor' endings were publiched in 2003, the culmination of an NIH grant of 34 years duration with two successive Jacob Javits Investigator awards. While closing my laboratory I was appointed Chair of the History Committee of the Society for Neuroscience (SfN) and was awarded a grant from the Alfred P. Sloan Foundation for constructing a "recent history" website for neuroscience which can be found as "WReN" on the SfN web page. During this time I have devoted my principal scholarly efforts to original research on the development of comparative anatomy of the brain in the 17th century, culminating in two recent (2003) papers in the Journal of the History of Neuroscience. In the academic year 2001-2002, I was invited as a Resident Scholar at the Getty Research Institute where I worked on the history of multiple frame imaging as part of their program for that year called "Frames of Viewing". Returning to the ULCA campus, my principal activity, aside from some minor lab bench collaborative efforts, has been devoted to work on a book on the theme of Multiple Frames (a tentative title) dealing with visual neurobiology and how visual art is constructed from temporal and spacial frames.

neurobiology, neuroscience, visual, history of neuroscience, history


Kruger, L. and Swanson, L.W.   1710: The Introduction of Experimental Nervous Systems Physiology and Anatomy by Francois Pourfour du Petit, in Brain, Mind, and Medicine: Essays in 18th Century Neuroscience, 2007; 101-115 (in press).
Kruger, L.   The sensory neuron and the triumph of Camillo Golgi, Brain Res. Rev. Jan. 30 EPub, 2007; .
Kruger, L., Otis, T.S.   Whither withered Golgi? A retrospective evaluation of reticularist and synaptic constructs, Brain Res, Bull, 2007; 72: 201-207.
Yan X, Koos BJ, Kruger L, Linden J, Murray TF.   Characterization of [(125) I]ZM 241385 binding to adenosine A(2A) receptors in the pineal of sheep brain, Brain Res, 2006; 1096: 30-9.
Kruger, L. and Rice, F.L.   The Histology of Nociceptors and Electron Microscopy (EM) of Nociceptors, In Encyclopedia of Pain (print and digital), 2006; .
Kruger, L.   The scientific impact of Dr. N. Tulp, portrayed in Rembrandt's "Anatomy Lesson", J Hist Neurosci, 2005; 14: 85-92.
Kruger, L.   An early illustrated comparative anatomy of the brain: Samuel Collin's A Systeme of Anatomy (1685) and the emergence of comparative neurology in 17th century England, J Hist Neurosci, 2004; 13: 195-217.
Koos, B.J., Kawasaki, Y., Hari, A., Bohoqez, F., Jan, C., Roostaeian, J., Wilson, C., Kruger, L.   Electrical stimulation of the posteromedial thalamus modulates breathing in unanesthetized fetal sheep, J Appl Physiol, 2004; 96(1): 115-123.
Peters A, Rosenbluth J, Pappas G, Kruger L, Mugnaini E.   Sanford Louis Palay (1918-2002), Nat Acad Sci Biog Mem, 2004; 84: 2-16.
Kruger, L., Greenspan, J.   Sensory System, Cutaneous, In Encyclopedia of Neuroscience 3rd Edition (electronic), 2004; .
Koos, BJ Kawasaki, Y Hari, A Bohorquez, F Jan, C Roostaeian, J Wilson, CL Kruger, L   Electrical stimulation of the posteromedial thalamus modulates breathing in unanesthetized fetal sheep Journal of applied physiology (Bethesda, Md. : 1985) , 2004; 96(1): 115-23.
Kruger, L   Edward Tyson's 1680 account of the 'porpess' brain and its place in the history of comparative neurology Journal of the history of the neurosciences. , 2003; 12(4): 339-49.
Kruger, L Kavookjian, AM Kumazawa, T Light, AR Mizumura, K   Nociceptor structural specialization in canine and rodent testicular "free" nerve endings The Journal of comparative neurology. , 2003; 463(2): 197-211.
Kruger, L., A.R. Light, and F.E. Schweizer   Axonal terminals of sensory neruons and their morphological diversity, J. Neurocytol, 2003; 32: 205-216.
Neubert, JK Maidment, NT Matsuka, Y Adelson, DW Kruger, L Spigelman, I   Inflammation-induced changes in primary afferent-evoked release of substance P within trigeminal ganglia in vivo Brain research. , 2000; 871(2): 181-91.
Koos, BJ Chau, A Matsuura, M Punla, O Kruger, L   Thalamic lesions dissociate breathing inhibition by hypoxia and adenosine in fetal sheep American journal of physiology. Regulatory, integrative and comparative physiology. , 2000; 278(4): R831-7.
Sofroniew, MV Bush, TG Blumauer, N Lawrence Kruger, Mucke, L Johnson, MH   Genetically-targeted and conditionally-regulated ablation of astroglial cells in the central, enteric and peripheral nervous systems in adult transgenic mice Brain research. , 1999; 835(1): 91-5.
Koos, BJ Chau, A Matsuura, M Punla, O Kruger, L   Thalamic locus mediates hypoxic inhibition of breathing in fetal sheep Journal of neurophysiology. , 1998; 79(5): 2383-93.
Koos, BJ Kruger, L Murray, TF   Source of extracellular brain adenosine during hypoxia in fetal sheep Brain research. , 1997; 778(2): 439-42.
Adelson, DW Wei, JY Kruger, L   Warm-sensitive afferent splanchnic C-fiber units in vitro Journal of neurophysiology. , 1997; 77(6): 2989-3002.
Adelson, D.W., J.Y. Wei, and L. Kruger   H202-sensitivity of splanchnic afferent C-fiber units in vitro, J. Neurophysiol, 1996; 76: 371-380.

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