Publications:
A selected list of publications:
Jide Tian,
Blake Middleton,
Daniel L Kaufman
GABA A-Receptor Agonists Limit Pneumonitis and Death in Murine Coronavirus-Infected Mice,
Viruses,
2021;
.
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Jide Tian, Blake Middleton, and Daniel L. Kaufman
GABA administration limits viral replication and pneumonitis in a mouse model of COVID-19,
BioRxiv,
2021; https://www.biorxiv.org/content/10.1101/2021.02.09.430446v2:
.
Tian J, Dang H, Middleton B, Kaufman DL.
Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication,
Scientific Reports,
2017;
.
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Tian, J., Dang, H., Nguyen, A.V., Chen, Z, Kaufman, DL
Combined therapy with GABA and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T cell autoimmunity and promoting ß-cell replication in newly diabetic NOD mice,
Diabetes,
2014; 63:
3128-3134.
LaÄan Goran, Dang Hoa, Middleton Blake, Horwitz Marcus A, Tian Jide, Melega William P, Kaufman Daniel L
Bacillus Calmette-Guerin vaccine-mediated neuroprotection is
associated with regulatory T-cell induction in the
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of
Parkinson's disease
Journal of neuroscience research,
2013;
.
Bilousova Tina, Dang Hoa, Xu Willem, Gustafson Sarah, Jin Yingli, Wickramasinghe Lalinda, Won Tony, Bobarnac Gabriela, Middleton Blake, Tian Jide, Kaufman Daniel L
Major histocompatibility complex class I molecules modulate embryonic neuritogenesis and neuronal polarization
Journal of Neuroimmunology,
2012; 247(1-2):
1-8.
Washburn, L.R., Zekzer, D., Eitan, S., Lu, Y., Dang, H., Middleton, B., Evans, C.J., Tian, J., Kaufman, D.L.
A potential role for shed soluble major histocompatibility class I molecules as modulators of neurite outgrowth. ,
PLoS ONE,
2011; e18439:
.
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Yong, J., Lacan, G., Dang, H., Hsieh, T., Middleton, B., Wasserfall, C., Tian, J., Melega, W.P., Kaufman, D.L.
BCG vaccine-induced neuroprotection in a mouse model of Parkinson's Disease,
PLoS ONE,
2011; 6(1):e16610. PMCID: PMC3031604:
.
Tian, J., Dang, H., Kaufman D.L
Combining Antigen-Based Therapy with GABA Treatment Synergistically Prolongs Survival of Transplanted ß-Cells in Diabetic NOD Mice,
PLoS ONE,
2011; e25337:
.
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Wu ZP, Washburn L, Bilousova TV, Boudzinskaia M, Escande-Beillard N, Querubin J, Dang H, Xie CW, Tian J, Kaufman DL
Enhanced neuronal expression of major histocompatibility complex class I leads to aberrations in neurodevelopment and neurorepair,
J Neuroimmunol,
2011; 232:
8-16.
Wu Zhongqi-Phyllis, Washburn Lorraine, Bilousova Tina V, Boudzinskaia Maia, Escande-Beillard Nathalie, Querubin Jyes, Dang Hoa, Xie Cui-Wei, Tian Jide, Kaufman Daniel L
Enhanced neuronal expression of major histocompatibility complex class
I leads to aberrations in neurodevelopment and neurorepair
Journal of neuroimmunology,
2011; 232(1-2):
8-16.
Wu ZP, Bilousova T, Dang H, Hsieh T, Tian J, Kaufman DL
Major histocompatibility complex class I-mediated inhibition of neurite outgrowth from peripheral nerves,
Immunol Lett,
2011; 135:
118-123.
Yong, J., Rasooly, J., Dang, H,, Lu, Y., Middleton, B., Zhang, Z., Hon, L., Namavari, M., Stout, D., Atkinson, M.A., Tian, J., Gambhir, S.S., Kaufman, D.L
Multimodality Imaging of ß-cells in Mouse Models of Type I and II Diabetes,
Diabetes,
2011; 60:
1383-1392 .
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Yong Jing, Rasooly Julia, Dang Hoa, Lu Yuxin, Middleton Blake, Zhang Zesong, Hon Larry, Namavari Mohammad, Stout David B, Atkinson Mark A, Tian Jide, Gambhir Sanjiv Sam, Kaufman Daniel L
Multimodality imaging of β-cells in mouse models of type 1 and 2
diabetes
Diabetes,
2011; 60(5):
1383-92.
Tian, J., Young, J, Dang H., and Kaufman DL.
Oral GABA treatment down-regulates inflammatory responses in a mouse model of rheumatoid arthritis,
Autoimmunity,
2011; 44 :
465-470.
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Tian, J., Dang, H.N., Yong, J., Chui W-S, Dizon, M.P.G., Yaw, C.K.Y. Kaufman, D.L
Oral Treatment with γ-Aminobutyric Acid Improves Glucose Tolerance and Insulin Sensitivity by Inhibiting Inflammation in High Fat Diet-Fed Mice,
PLoS ONE,
2011; e25338:
.
Joseph, S.M., Wu, Z-P, Zdunowski, S., Middleton, B., Boudzinskaia, M, Wong, B., Ali, N., Zhong, H., Yong, J., Washburn, L., Escande-Beillard, N., Dang, N., Edgerton, V.R., Tillakaratne. N.J.K., Kaufman, D.L.,
Transgenic mice with enhanced neuronal MHC class I expression recover locomotor function better after spinal cord injury,
J Neurosci Res,
2011; 89:
365-372.
Joseph M Selvan, Bilousova Tina, Zdunowski Sharon, Wu Zhongqi-Phyllis, Middleton Blake, Boudzinskaia Maia, Wong Bonnie, Ali Noore, Zhong Hui, Yong Jing, Washburn Lorraine, Escande-Beillard Nathalie, Dang Hoa, Edgerton V Reggie, Tillakaratne Niranjala J K, Kaufman Daniel L
Transgenic mice with enhanced neuronal major histocompatibility
complex class I expression recover locomotor function better after
spinal cord injury
Journal of neuroscience research,
2011; 89(3):
365-72.
Escande-Beillard Nathalie, Washburn Lorraine, Zekzer Dan, Wu Zhongqi-Phyllis, Eitan Shoshy, Ivkovic Sonja, Lu Yuxin, Dang Hoa, Middleton Blake, Bilousova Tina V, Yoshimura Yoshitaka, Evans Christopher J, Joyce Sebastian, Tian Jide, Kaufman Daniel L
Neurons preferentially respond to self-MHC class I allele products
regardless of peptide presented
Journal of immunology (Baltimore, Md. : 1950),
2010; 184(2):
816-23.
Escande-Beillard, N., Washburn, L., Zekzer, D., Wu, Z-P., , Eitan, S., Ivkovic, S., Lu, Y., Dang, H., Middleton, B., Yoshimura, Y., Evans, C.J., Joyce, S., Tian, J., and Kaufman, D.L.
Neurons preferentially respond to self-major histocompatibility complex class I allele products regardless of peptide presented,
J. Immunol,
2010; 184:
816-823.
Tian, J., Dang, H., von Boehmer, H., Jaeckel, E., Kaufman, D.L
Transgenically-induced GAD tolerance curtails the development of early ß-cell autoreactivities but causes the subsequent development of supernormal autoreactivities to other ß-cell antigens,
Diabetes,
2009; Dec.:
.
L.R. Washburn, H. Dang, J. Tian, D.L. Kaufman.
The postnatal maternal environment influences diabetes development in nonobese diabetic mice,
J. Autoimmunity,
2007; 28:
19-23.
Tian, J., Zekzer, D., Lu, Y., Dang, H.and Kaufman, DL.
B cells are crucial for determinant spreading of T cell autoimmunity among b-cell antigens in diabetes-prone NOD mice,
Journal of Immunology,
2006; 176:
2654-2661.
Lu, Y., Dang, H., Middleton, B., Zhang, Z., Washburn, L., Stout, D.B., Campbell-Thompson, M., Atkinson, M.A., Phelps, M., Gambhir, S.S, Tian, J., and Kaufman, D.L.
Noninvasive imaging of islet grafts using positron emission tomography,
PNAS,
2006; 103:
11294-11299.
Olcott, A.P., Tian, J., Walker, V., Dang, H., Middleton, B., Adorini, L. Washburn, and Kaufman, D.L
Antigen-based therapies utilizing ignored determinants of beta-cell antigens can more effectively inhibit late-stage autoimmune disease in diabetes-prone mice,
J. Immunol,
2005; 175:
1991-1999.
Lu, Y Dang, H Middleton, B Zhang, Z Washburn, L Campbell-Thompson, M Atkinson, MA Gambhir, SS Tian, J Kaufman, DL
Bioluminescent monitoring of islet graft survival after transplantation
Molecular therapy : the journal of the American Society of Gene Therapy. ,
2004; 9(3):
428-35.
Tian, J., Olcott A.P. and Kaufman, D.L.
Antigen-based immunotherapy drives the precocious developement of autoimmunity,
J. Immunol,
2002; 169:
6564-6569.
Kaufman, D.L and Tobin, A.J.
Glutamic Acid Decarboxylases: Insights into Neural Signaling and Autoimmune Diabetes,
Encyclopedia of Molecular Medicine ,
2002;
1459-1462.
Kaufman, D.L and Tobin, A.J.
Glutamic Acid Decarboxylases: Insights into Neural Signaling and Autoimmune Diabetes,
Encyclopedia of Molecular Medicine,
2001;
.
Jide Tian and Daniel Kaufman.
Lipopolysacharide-activated B cells as immunotherapy in NOD mice ,
J. Immunology , ,
2001; 167:
1081-1089.
Kaufman, DL Tisch, R Sarvetnick, N Chatenoud, L Harrison, LC Haskins, K Quinn, A Sercarz, E Singh, B von Herrath, M Wegmann, D Wen, L Zekzer, D
Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop
Diabetes. ,
2001; 50(11):
2459-63.
Jide Tian, Silvia Gregori, Luciano Aldorini and Daniel L. Kaufman.
The frequency of high avidity T cells determines the chronology of determinant spreading,
J. Immunology,
2001; 166:
7144-7150.
Jide Tian and Daniel L. Kaufman
Control of Autoimmune Diabetes. (commentary),
Science,
2000; 287:
191a.
Tian et al.
Antigen-based Immunotherapy: From Animal Models to Man?,
Immunology Today,
1999; 20:
190-195.
Tian, J, et al.
GABA-A receptors mediate inhbition of T cell responses,
J. Neuroimmunology,
1999; 96:
21-28.
Olcott, A.P., Tian, J. and Kaufman, D.L.
Autoantigen-based immunotherapy for human IDDM,
Diabetes Prevention and Therapy ,
1996; 10:
20-21.
Tian, J Clare-Salzler, M Herschenfeld, A Middleton, B Newman, D Mueller, R Arita, S Evans, C Atkinson, MA Mullen, Y Sarvetnick, N Tobin, AJ Lehmann, PV Kaufman, DL
Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice
Nature medicine. ,
1996; 2(12):
1348-53.
Tian, J., et al.
Nasal administration of glutamate decaboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes,
J. Exp. Med,
1996; 183:
1561-1567.
Kaufman, DL Keith, DE Anton, B Tian, J Magendzo, K Newman, D Tran, TH Lee, DS Wen, C Xia, YR
Characterization of the murine mu opioid receptor gene
The Journal of biological chemistry. ,
1995; 270(26):
15877-83.
Atkinson et al.
Islet cell autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes,
J. Clinical. Invest. ,
1993; 91, :
350-355.
Kaufman, D.L., et al.
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes,
Nature,
1993; 366:
69-72.
Atkinson, M.A.et al.
Peripheral blood mononuclear cells respond to glutamate decarboxylase in insulin-dependent diabetes,
Lancet,
1992; 339:
458-459.
Tian J, Dillion B, Henley J, Comai L, Kaufman DL.
GABA-receptors are a new druggable target for limiting disease severity, lung viral load, and death in SARS-CoV-2 infected mice,
BioRxiv,
2022;
.
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