Publications:
A selected list of publications:
Antonios Joseph P, Soto Horacio, Everson Richard G, Moughon Diana, Orpilla Joey R, Shin Namjo P, Sedighim Shaina, Treger Janet, Odesa Sylvia, Tucker Alexander, Yong William H, Li Gang, Cloughesy Timothy F, Liau Linda M, Prins Robert M
Immunosuppressive tumor-infiltrating myeloid cells mediate adaptive
immune resistance via a PD-1/PD-L1 mechanism in glioblastoma
Neuro-oncology,
2017;
.
Abdaljaleel Maram, Mazumder Rajarshi, Patel Chirag B, Im Kyuseok, Pope Whitney, Liau Linda M, Vinters Harry V, Yong William H
Multiple calcifying pseudoneoplasms of the neuraxis (MCAPNON):
Distinct entity, CAPNON variant, or old neurocysticercosis?
Neuropathology : official journal of the Japanese Society of Neuropathology,
2016;
.
Lee Seung J, Bui Timothy T, Chen Cheng Hao Jacky, Lagman Carlito, Chung Lawrance K, Sidhu Sabrin, Seo David J, Yong William H, Siegal Todd L, Kim Minsu, Yang Isaac
Central Neurocytoma: A Review of Clinical Management and
Histopathologic Features
Brain tumor research and treatment,
2016; 4(2):
49-57.
Lamers Susanna L, Rose Rebecca, Maidji Ekaterina, Agsalda-Garcia Melissa, Nolan David J, Fogel Gary B, Salemi Marco, Garcia Debra L, Bracci Paige, Yong William, Commins Deborah, Said Jonathan, Khanlou Negar, Hinkin Charles H, Sueiras Miguel Valdes, Mathisen Glenn, Donovan Suzanne, Shiramizu Bruce, Stoddart Cheryl A, McGrath Michael S, Singer Elyse J
HIV DNA Is Frequently Present within Pathologic Tissues Evaluated at
Autopsy from Combined Antiretroviral Therapy-Treated Patients with
Undetectable Viral Loads
Journal of virology,
2016; 90(20):
8968-83.
Nguyen HuyTram N, Lie Amy, Li Tie, Chowdhury Reshmi, Liu Fei, Ozer Byram, Wei Bowen, Green Richard M, Ellingson Benjamin M, Wang He-Jing, Elashoff Robert, Liau Linda M, Yong William H, Nghiemphu Phioanh L, Cloughesy Timothy, Lai Albert
Human TERT promoter mutation enables survival advantage from MGMT
promoter methylation in IDH1 wild-type primary glioblastoma treated by
standard chemoradiotherapy
Neuro-oncology,
2016; 90(20):
8968-83.
Antonios Joseph P, Soto Horacio, Everson Richard G, Orpilla Joey, Moughon Diana, Shin Namjo, Sedighim Shaina, Yong William H, Li Gang, Cloughesy Timothy F, Liau Linda M, Prins Robert M
PD-1 blockade enhances the vaccination-induced immune response in
glioma
JCI insight,
2016; 1(10):
2468-77.
Ellingson Benjamin M, Nguyen Huytram N, Lai Albert, Nechifor Ruben E, Zaw Okkar, Pope Whitney B, Yong William H, Nghiemphu Phioanh L, Liau Linda M, Cloughesy Timothy F
Contrast-enhancing tumor growth dynamics of preoperative,
treatment-naive human glioblastoma
Cancer,
2016; 122(11):
1718-27.
Hsu Melody S, Sedighim Shaina, Wang Tina, Antonios Joseph P, Everson Richard G, Tucker Alexander M, Du Lin, Emerson Ryan, Yusko Erik, Sanders Catherine, Robins Harlan S, Yong William H, Davidson Tom B, Li Gang, Liau Linda M, Prins Robert M
TCR Sequencing Can Identify and Track Glioma-Infiltrating T Cells
after DC Vaccination
Cancer immunology research,
2016; 4(5):
412-8.
Choy Winward, Terterov Sergei, Kaprealian Tania B, Trang Andy, Ung Nolan, DeSalles Antonio, Chung Lawrance K, Martin Neil, Selch Michael, Bergsneider Marvin, Vinters Harry V, Yong William H, Yang Isaac
Predictors of recurrence following resection of intracranial
chordomas
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia,
2015; 22(11):
1792-6.
Yong William H, Shabihkhani Maryam, Telesca Donatello, Yang Shuai, Tso Jonathan L, Menjivar Jimmy C, Wei Bowen, Lucey Gregory M, Mareninov Sergey, Chen Zugen, Liau Linda M, Lai Albert, Nelson Stanley F, Cloughesy Timothy F, Tso Cho-Lea
Ribosomal Proteins RPS11 and RPS20, Two Stress-Response Markers of
Glioblastoma Stem Cells, Are Novel Predictors of Poor Prognosis in
Glioblastoma Patients
PloS one,
2015; 10(10):
e0141334.
Harris Robert J, Cloughesy Timothy F, Liau Linda M, Prins Robert M, Antonios Joseph P, Li Debiao, Yong William H, Pope Whitney B, Lai Albert, Nghiemphu Phioanh L, Ellingson Benjamin M
pH-weighted molecular imaging of gliomas using amine chemical exchange
saturation transfer MRI
Neuro-oncology,
2015; 17(11):
1514-24.
Liu Feng, Hon Gary C, Villa Genaro R, Turner Kristen M, Ikegami Shiro, Yang Huijun, Ye Zhen, Li Bin, Kuan Samantha, Lee Ah Young, Zanca Ciro, Wei Bowen, Lucey Greg, Jenkins David, Zhang Wei, Barr Cathy L, Furnari Frank B, Cloughesy Timothy F, Yong William H, Gahman Timothy C, Shiau Andrew K, Cavenee Webster K, Ren Bing, Mischel Paul S
EGFR Mutation Promotes Glioblastoma through Epigenome and
Transcription Factor Network Remodeling
Molecular cell,
2015; 60(2):
307-18.
Masui Kenta, Tanaka Kazuhiro, Ikegami Shiro, Villa Genaro R, Yang Huijun, Yong William H, Cloughesy Timothy F, Yamagata Kanato, Arai Nobutaka, Cavenee Webster K, Mischel Paul S
Glucose-dependent acetylation of Rictor promotes targeted cancer
therapy resistance
Proceedings of the National Academy of Sciences of the United States of America,
2015; 112(30):
9406-11.
Karavaeva Elena, Harris Robert J, Leu Kevin, Shabihkhani Maryam, Yong William H, Pope Whitney B, Lai Albert, Nghiemphu Phioanh L, Liau Linda M, Chen Wei, Czernin Johannes, Cloughesy Timothy F, Ellingson Benjamin M
Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion
Coefficient (ADC), and Proliferation Rate in Recurrent Malignant
Gliomas
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging,
2015; 17(3):
434-42.
Li Sichen, Chowdhury Reshmi, Liu Fei, Chou Arthur P, Li Tie, Mody Reema R, Lou Jerry J, Chen Weidong, Reiss Jean, Soto Horacio, Prins Robert, Liau Linda M, Mischel Paul S, Nghiemphu Phioanh L, Yong William H, Cloughesy Timothy F, Lai Albert
Tumor-suppressive miR148a is silenced by CpG island hypermethylation
in IDH1-mutant gliomas
Clinical cancer research : an official journal of the American Association for Cancer Research,
2014; 20(22):
5808-22.
Piccioni David E, Selfridge Julia, Mody Reema R, Chowdhury Reshmi, Li Sichen, Lalezari Shadi, Wawrzynski James, Quan Jennifer, Zurayk Mira, Chou Arthur P, Sanchez Desiree E, Liau Linda M, Ellingson Benjamin M, Pope Whitney B, Nghiemphu Phioanh L, Green Richard M, Wang He-Jing, Yong William H, Elashoff Robert, Cloughesy Timothy F, Lai Albert
Deferred use of bevacizumab for recurrent glioblastoma is not
associated with diminished efficacy
Neuro-oncology,
2014; 16(6):
815-22.
Lou Jerry J, Mirsadraei Leili, Sanchez Desiree E, Wilson Ryan W, Shabihkhani Maryam, Lucey Gregory M, Wei Bowen, Singer Elyse J, Mareninov Sergey, Yong William H
A review of room temperature storage of biospecimen tissue and nucleic
acids for anatomic pathology laboratories and biorepositories
Clinical biochemistry,
2014; 47(4-5):
267-73.
Shabihkhani Maryam, Lucey Gregory M, Wei Bowen, Mareninov Sergey, Lou Jerry J, Vinters Harry V, Singer Elyse J, Cloughesy Timothy F, Yong William H
The procurement, storage, and quality assurance of frozen blood and
tissue biospecimens in pathology, biorepository, and biobank settings
Clinical biochemistry,
2014; 47(4-5):
258-66.
Masui Kenta, Tanaka Kazuhiro, Akhavan David, Babic Ivan, Gini Beatrice, Matsutani Tomoo, Iwanami Akio, Liu Feng, Villa Genaro R, Gu Yuchao, Campos Carl, Zhu Shaojun, Yang Huijun, Yong William H, Cloughesy Timothy F, Mellinghoff Ingo K, Cavenee Webster K, Shaw Reuben J, Mischel Paul S
mTOR complex 2 controls glycolytic metabolism in glioblastoma through
FoxO acetylation and upregulation of c-Myc
Cell metabolism,
2013; 18(5):
726-39.
Mareninov Sergey, De Jesus Jason, Sanchez Desiree E, Kay Andrew B, Wilson Ryan W, Babic Ivan, Chen Weidong, Telesca Donatello, Lou Jerry J, Mirsadraei Leili, Gardner Tracie P, Khanlou Negar, Vinters Harry V, Shafa Bob B, Lai Albert, Liau Linda M, Mischel Paul S, Cloughesy Timothy F, Yong William H
Lyophilized brain tumor specimens can be used for histologic, nucleic
acid, and protein analyses after 1 year of room temperature storage
Journal of neuro-oncology,
2013; 113(3):
365-73.
Babic Ivan, Anderson Erik S, Tanaka Kazuhiro, Guo Deliang, Masui Kenta, Li Bing, Zhu Shaojun, Gu Yuchao, Villa Genaro R, Akhavan David, Nathanson David, Gini Beatrice, Mareninov Sergey, Li Rui, Camacho Carolina Espindola, Kurdistani Siavash K, Eskin Ascia, Nelson Stanley F, Yong William H, Cavenee Webster K, Cloughesy Timothy F, Christofk Heather R, Black Douglas L, Mischel Paul S
EGFR mutation-induced alternative splicing of Max contributes to
growth of glycolytic tumors in brain cancer
Cell metabolism,
2013; 17(6):
1000-8.
Lalezari Shadi, Chou Arthur P, Tran Anh, Solis Orestes E, Khanlou Negar, Chen Weidong, Li Sichen, Carrillo Jose A, Chowdhury Reshmi, Selfridge Julia, Sanchez Desiree E, Wilson Ryan W, Zurayk Mira, Lalezari Jonathan, Lou Jerry J, Ormiston Laurel, Ancheta Karen, Hanna Robert, Miller Paul, Piccioni David, Ellingson Benjamin M, Buchanan Colin, Mischel Paul S, Nghiemphu Phioanh L, Green Richard, Wang He-Jing, Pope Whitney B, Liau Linda M, Elashoff Robert M, Cloughesy Timothy F, Yong William H, Lai Albert
Combined analysis of O6-methylguanine-DNA methyltransferase protein
expression and promoter methylation provides optimized prognostication
of glioblastoma outcome
Neuro-oncology,
2013; 15(3):
370-81.
Lazovic Jelena, Soto Horacio, Piccioni David, Lou Jerry R, Li Sichen, Mirsadraei Leili, Yong William, Prins Robert, Liau Linda M, Ellingson Benjamin M, Cloughesy Timothy F, Lai Albert, Pope Whitney B
Detection of 2-hydroxyglutaric acid in vivo by proton magnetic
resonance spectroscopy in U87 glioma cells overexpressing isocitrate
dehydrogenase-1 mutation
Neuro-oncology,
2012; 14(12):
1465-72.
Chou Arthur P, Chowdhury Reshmi, Li Sichen, Chen Weidong, Kim Andrew J, Piccioni David E, Selfridge Julia M, Mody Reema R, Chang Stephen, Lalezari Shadi, Lin Jeffrey, Sanchez Desiree E, Wilson Ryan W, Garrett Matthew C, Harry Bret, Mottahedeh Jack, Nghiemphu Phioanh L, Kornblum Harley I, Mischel Paul S, Prins Robert M, Yong William H, Cloughesy Timothy, Nelson Stanley F, Liau Linda M, Lai Albert
Identification of retinol binding protein 1 promoter hypermethylation
in isocitrate dehydrogenase 1 and 2 mutant gliomas
Journal of the National Cancer Institute,
2012; 104(19):
1458-69.
Lai Albert, Kharbanda Samir, Pope Whitney B, Tran Anh, Solis Orestes E, Peale Franklin, Forrest William F, Pujara Kanan, Carrillo Jose A, Pandita Ajay, Ellingson Benjamin M, Bowers Chauncey W, Soriano Robert H, Schmidt Nils O, Mohan Sankar, Yong William H, Seshagiri Somasekar, Modrusan Zora, Jiang Zhaoshi, Aldape Kenneth D, Mischel Paul S, Liau Linda M, Escovedo Cameron J, Chen Weidong, Nghiemphu Phioanh Leia, James C David, Prados Michael D, Westphal Manfred, Lamszus Katrin, Cloughesy Timothy, Phillips Heidi S
Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma
from a distinct cell of origin
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
2011; 29(34):
4482-90.
Solis Orestes E, Mehta Rupal I, Lai Albert, Mehta Rashi I, Farchoukh Lama O, Green Richard M, Cheng Jerry C, Natarajan Sathima, Vinters Harry V, Cloughesy Timothy, Yong William H
Rosette-forming glioneuronal tumor: a pineal region case with IDH1 and
IDH2 mutation analyses and literature review of 43 cases
Journal of neuro-oncology,
2011; 102(3):
477-84.
Ellison David W, Dalton James, Kocak Mehmet, Nicholson Sarah Leigh, Fraga Charles, Neale Geoff, Kenney Anna M, Brat Dan J, Perry Arie, Yong William H, Taylor Roger E, Bailey Simon, Clifford Steven C, Gilbertson Richard J
Medulloblastoma: clinicopathological correlates of SHH, WNT, and
non-SHH/WNT molecular subgroups
Acta neuropathologica,
2011; 121(3):
381-96.
Leung Alina A, Lou Jerry J, Mareninov Sergey, Silver Steven S, Routbort Mark J, Riben Michael, Andrechak Gary, Yong William H
Tolerance testing of passive radio frequency identification tags for
solvent, temperature, and pressure conditions encountered in an
anatomic pathology or biorepository setting
Journal of pathology informatics,
2010; 1(9):
21.
Sun Jing, Masterman-Smith Michael D, Graham Nicholas A, Jiao Jing, Mottahedeh Jack, Laks Dan R, Ohashi Minori, DeJesus Jason, Kamei Ken-ichiro, Lee Ki-Bum, Wang Hao, Yu Zeta T F, Lu Yi-Tsung, Hou Shuang, Li Keyu, Liu Max, Zhang Nangang, Wang Shutao, Angenieux Brigitte, Panosyan Eduard, Samuels Eric R, Park Jun, Williams Dirk, Konkankit Vera, Nathanson David, van Dam R Michael, Phelps Michael E, Wu Hong, Liau Linda M, Mischel Paul S, Lazareff Jorge A, Kornblum Harley I, Yong William H, Graeber Thomas G, Tseng Hsian-Rong
A microfluidic platform for systems pathology: multiparameter
single-cell signaling measurements of clinical brain tumor specimens
Cancer research,
2010; 70(15):
6128-38.
Mehta Rupal I, Mehta Rashi I, Solis Orestes E, Jahan Reza, Salamon Noriko, Tobis Jonathan M, Yong William H, Vinters Harry V, Fishbein Michael C
Hydrophilic polymer emboli: an under-recognized iatrogenic cause of
ischemia and infarct
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc,
2010; 23(7):
921-30.
Guo Deliang, Prins Robert M, Dang Julie, Kuga Daisuke, Iwanami Akio, Soto Horacio, Lin Kelly Y, Huang Tiffany T, Akhavan David, Hock M Benjamin, Zhu Shaojun, Kofman Ava A, Bensinger Steve J, Yong William H, Vinters Harry V, Horvath Steve, Watson Andrew D, Kuhn John G, Robins H Ian, Mehta Minesh P, Wen Patrick Y, DeAngelis Lisa M, Prados Michael D, Mellinghoff Ingo K, Cloughesy Timothy F, Mischel Paul S
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant
pathway sensitizes glioblastomas to antilipogenic therapy
Science signaling,
2009; 2(101):
ra82.