A Short Biography:
Dr. Tracy Xie is a professor at the Department of Psychiatry and Biobehavioral Sciences. She received her doctorate degree at Peking University in China and postdoctoral training at National Institute of Health (NIH)and Duke University in US. Her laboratory investigates cellular mechanisms of hippocampal synaptic plasticity and memory, and plasticity changes during aging, Alzheimer's disease and drug dependnce.
Dr. Tracy Xie is a professor at the Department of Psychiatry and Biobehavioral Sciences. She earned her doctorate degree in medicine and physiology at Peking University, China. She received postdoctoral training in electrophysiology and molecular biology at National Institute of Health (NIH) and Duke University in North Carolina, where she studied regulation of hippocampal synaptic plasticity by endogenous neuropeptides. Since joining UCLA faculty in 1995, Dr. Xie has been studying cellular mechanisms of neural and synaptic plasticity, and implications of such mechanisms in drug dependence and memory loss related to aging and Alzheimer's disease. Her research is funded by grants from National Institute of Aging (NIA), National Institute on Drug abuse (NIDA), and Alzheimer's Association.
A selected list of publications:
Wu Zhongqi-Phyllis, Washburn Lorraine, Bilousova Tina V, Boudzinskaia Maia, Escande-Beillard Nathalie, Querubin Jyes, Dang Hoa, Xie Cui-Wei, Tian Jide, Kaufman Daniel L
Enhanced neuronal expression of major histocompatibility complex class
I leads to aberrations in neurodevelopment and neurorepair
Journal of neuroimmunology,
Li Huiyuan, Monien Bernhard H, Lomakin Aleksey, Zemel Reeve, Fradinger Erica A, Tan Miao, Spring Sean M, Urbanc Brigita, Xie Cui-Wei, Benedek George B, Bitan Gal
Mechanistic Investigation of the Inhibition of Abeta42 Assembly and Neurotoxicity by Abeta42 C-Terminal Fragments
Fradinger Erica A, Monien Bernhard H, Urbanc Brigita, Lomakin Aleksey, Tan Miao, Li Huiyuan, Spring Sean M, Condron Margaret M, Cruz Luis, Xie Cui-Wei, Benedek George B, Bitan Gal
C-terminal peptides coassemble into Abeta42 oligomers and protect
neurons against Abeta42-induced neurotoxicity
Proceedings of the National Academy of Sciences of the United States of America,
Walwyn, W. M. Keith, D. E., Jr. Wei, W. Tan, A. M. Xie, C. W. Evans, C. J. Kieffer, B. L. Maidment, N. T.
Functional coupling, desensitization and internalization of virally expressed mu opioid receptors in cultured dorsal root ganglion neurons from mu opioid receptor knockout mice