Publications:
A selected list of publications:
Donahue, T., Tran, L., Wu, H., Toste, P., Wu, N., Wong, J., Li, X., Dawson, D., Wu, X., and Malkhassian, D
Endoscopically Acquired Pancreatic Cyst Fluid MicroRNA 21 and 221 are associated with Invasive Cancer ,
American Journal of Gastroenterology,
2013;
.
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Smith Kathleen B, Tran Linh M, Tam Brenna M, Shurell Elizabeth M, Li Yunfeng, Braas Daniel, Tap William D, Christofk Heather R, Dry Sarah M, Eilber Fritz C, Wu Hong
Novel dedifferentiated liposarcoma xenograft models reveal PTEN
down-regulation as a malignant signature and response to PI3K pathway
inhibition
The American journal of pathology,
2013; 182(4):
1400-11.
Ruscetti, Marcus and Wu, Hong
PTEN and Prostate Cancer,
In D.J. Tindall's Book "Prostate Cancer: Biochemistry, Molecular Biology, and Genetics, Protein Reviews",
2013; (Chapter 4):
87-137.
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Mulholland, David, and Wu, Hong
Stem Cell Cells and Prostate Cancer ,
In Scott Cramer's Book "Stem Cells and Prostate Cancer",
2013; (Chapter 6):
77-90.
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Hill Reginald, Li Yunfeng, Tran Linh M, Dry Sarah, Hargan Calvopina Joseph, Garcia Alejandro J, Kim Christine, Wang Ying, Donahue Timothy R, Herschman Harvey R, Wu Hong
Cell Intrinsic Role of Cox-2 in Pancreatic Cancer Development
Molecular cancer therapeutics,
2012;
.
Graham Nicholas A, Tahmasian Martik, Kohli Bitika, Komisopoulou Evangelia, Zhu Maggie, Vivanco Igor, Teitell Michael A, Wu Hong, Ribas Antoni, Lo Roger S, Mellinghoff Ingo K, Mischel Paul S, Graeber Thomas G
Glucose deprivation activates a metabolic and signaling amplification
loop leading to cell death
Molecular systems biology,
2012; 8(1):
589.
Jiao Jing, Hindoyan Antreas, Wang Shunyou, Tran Linh M, Goldstein Andrew S, Lawson Devon, Chen Donghui, Li Yunfeng, Guo Changyong, Zhang Baohui, Fazli Ladan, Gleave Martin, Witte Owen N, Garraway Isla P, Wu Hong
Identification of CD166 as a surface marker for enriching prostate
stem/progenitor and cancer initiating cells
PloS one,
2012; 7(8):
e42564.
Donahue Timothy R, Tran Linh M, Hill Reginald, Li Yunfeng, Kovochich Anne, Calvopina Joseph H, Patel Sanjeet G, Wu Nanping, Hindoyan Antreas, Farrell James J, Li Xinmin, Dawson David W, Wu Hong
Integrative survival-based molecular profiling of human pancreatic
cancer
Clinical cancer research : an official journal of the American Association for Cancer Research,
2012; 18(5):
1352-63.
Hübner Anette, Mulholland David J, Standen Claire L, Karasarides Maria, Cavanagh-Kyros Julie, Barrett Tamera, Chi Hongbo, Greiner Dale L, Tournier Cathy, Sawyers Charles L, Flavell Richard A, Wu Hong, Davis Roger J
JNK and PTEN cooperatively control the development of invasive
adenocarcinoma of the prostate
Proceedings of the National Academy of Sciences of the United States of America,
2012; 109(30):
12046-51.
Di Vizio Dolores, Morello Matteo, Dudley Andrew C, Schow Peter W, Adam Rosalyn M, Morley Samantha, Mulholland David, Rotinen Mirja, Hager Martin H, Insabato Luigi, Moses Marsha A, Demichelis Francesca, Lisanti Michael P, Wu Hong, Klagsbrun Michael, Bhowmick Neil A, Rubin Mark A, D'Souza-Schorey Crislyn, Freeman Michael R
Large oncosomes in human prostate cancer tissues and in the
circulation of mice with metastatic disease
The American journal of pathology,
2012; 181(5):
1573-84.
Braas Daniel, Ahler Ethan, Tam Brenna, Nathanson David, Riedinger Mirielle, Benz Matthias R, Smith Kathleen B, Eilber Fritz C, Witte Owen N, Tap William D, Wu Hong, Christofk Heather R
Metabolomics Strategy Reveals Subpopulation of Liposarcomas Sensitive
to Gemcitabine Treatment
Cancer discovery,
2012; 2(12):
1109-1117.
Pope Whitney B, Prins Robert M, Albert Thomas M, Nagarajan Rajakumar, Yen Katharine E, Bittinger Mark A, Salamon Noriko, Chou Arthur P, Yong William H, Soto Horacio, Wilson Neil, Driggers Edward, Jang Hyun G, Su Shinsan M, Schenkein David P, Lai Albert, Cloughesy Timothy F, Kornblum Harley I, Wu Hong, Fantin Valeria R, Liau Linda M
Non-invasive detection of 2-hydroxyglutarate and other metabolites in
IDH1 mutant glioma patients using magnetic resonance spectroscopy
Journal of neuro-oncology,
2012; 107(1):
197-205.
Kim Tae Hyong, Song Jieun, Alcantara Llaguno Sheila R, Murnan Eric, Liyanarachchi Sandya, Palanichamy Kamalakannan, Yi Ji-Yeun, Viapiano Mariano Sebastian, Nakano Ichiro, Yoon Sung Ok, Wu Hong, Parada Luis F, Kwon Chang-Hyuk
Suppression of peroxiredoxin 4 in glioblastoma cells increases
apoptosis and reduces tumor growth
PloS one,
2012; 7(8):
e42818.
Palaskas Nicolaos, Larson Steven M, Schultz Nikolaus, Komisopoulou Evangelia, Wong Justin, Rohle Dan, Campos Carl, Yannuzzi Nicolas, Osborne Joseph R, Linkov Irina, Kastenhuber Edward R, Taschereau Richard, Plaisier Seema B, Tran Chris, Heguy Adriana, Wu Hong, Sander Chris, Phelps Michael E, Brennan Cameron, Port Elisa, Huse Jason T, Graeber Thomas G, Mellinghoff Ingo K
18F-fluorodeoxy-glucose positron emission tomography marks
MYC-overexpressing human basal-like breast cancers
Cancer research,
2011; 71(15):
5164-74.
Tsutsui Hideaki, Valamehr Bahram, Hindoyan Antreas, Qiao Rong, Ding Xianting, Guo Shuling, Witte Owen N, Liu Xin, Ho Chih-Ming, Wu Hong
An optimized small molecule inhibitor cocktail supports long-term
maintenance of human embryonic stem cells
Nature communications,
2011; 2(1):
167.
Mulholland David J, Tran Linh M, Li Yunfeng, Cai Houjian, Morim Ashkan, Wang Shunyou, Plaisier Seema, Garraway Isla P, Huang Jiaoti, Graeber Thomas G, Wu Hong
Cell Autonomous Role of PTEN in Regulating Castration-Resistant
Prostate Cancer Growth
Cancer cell,
2011; 19(6):
792-804.
Santiskulvong Chintda, Konecny Gottfried E, Fekete Mirela, Chen Kuang-Yui Michael, Karam Amer, Mulholland David, Eng Carol, Wu Hong, Song Min, Dorigo Oliver
Dual targeting of phosphoinositide 3-kinase and mammalian target of
rapamycin using NVP-BEZ235 as a novel therapeutic approach in human
ovarian carcinoma
Clinical cancer research : an official journal of the American Association for Cancer Research,
2011; 17(8):
2373-84.
Tap William D, Eilber Fritz C, Ginther Charles, Dry Sarah M, Reese Nicholas, Barzan-Smith Kate, Chen Hsiao-Wang, Wu Hong, Eilber Frederick R, Slamon Dennis J, Anderson Lee
Evaluation of well-differentiated/de-differentiated liposarcomas by
high-resolution oligonucleotide array-based comparative genomic
hybridization
Genes, chromosomes & cancer,
2011; 50(2):
95-112.
Guo Wei, Schubbert Suzanne, Chen James Y, Valamehr Bahram, Mosessian Sherly, Shi Hubing, Dang Nhi H, Garcia Consuelo, Theodoro Mariana F, Varella-Garcia Marileila, Wu Hong
Suppression of leukemia development caused by PTEN loss
Proceedings of the National Academy of Sciences of the United States of America,
2011; 108(4):
1409-14.
Sun Jing, Masterman-Smith Michael D, Graham Nicholas A, Jiao Jing, Mottahedeh Jack, Laks Dan R, Ohashi Minori, DeJesus Jason, Kamei Ken-ichiro, Lee Ki-Bum, Wang Hao, Yu Zeta T F, Lu Yi-Tsung, Hou Shuang, Li Keyu, Liu Max, Zhang Nangang, Wang Shutao, Angenieux Brigitte, Panosyan Eduard, Samuels Eric R, Park Jun, Williams Dirk, Konkankit Vera, Nathanson David, van Dam R Michael, Phelps Michael E, Wu Hong, Liau Linda M, Mischel Paul S, Lazareff Jorge A, Kornblum Harley I, Yong William H, Graeber Thomas G, Tseng Hsian-Rong
A microfluidic platform for systems pathology: multiparameter
single-cell signaling measurements of clinical brain tumor specimens
Cancer research,
2010; 70(15):
6128-38.
He Lina, Hou Xiaogang, Kanel Gary, Zeng Ni, Galicia Vivian, Wang Ying, Yang Jian, Wu Hong, Birnbaum Morris J, Stiles Bangyan L
The critical role of AKT2 in hepatic steatosis induced by PTEN loss
The American journal of pathology,
2010; 176(5):
2302-8.
Conway Anne E, Lindgren Anne, Galic Zoran, Pyle April D, Wu Hong, Zack Jerome A, Pelligrini Matteo, Teitell Michael A, Clark Amander T
A self-renewal program controls the expansion of genetically unstable
cancer stem cells in pluripotent stem cell-derived tumors
Stem cells (Dayton, Ohio),
2009; 27(1):
18-28.
Ruan,R., Ren, S., Li, J., Li, G., Kim, R., Gao, J., Wu, H., Wang Y.
Inducible and Cardiac Specific PTEN Inactivation Protects Ischemia/Reperfusion Injury,
Journal of Molecular and Cellular Cardiology,
2009; 46(2):
193-200.
Gregorian Caroline, Nakashima Jonathan, Dry Sarah M, Nghiemphu P Leia, Smith Kate Barzan, Ao Yan, Dang Julie, Lawson Gregory, Mellinghoff Ingo K, Mischel Paul S, Phelps Michael, Parada Luis F, Liu Xin, Sofroniew Michael V, Eilber Fritz C, Wu Hong
PTEN dosage is essential for neurofibroma development and malignant
transformation
Proceedings of the National Academy of Sciences of the United States of America,
2009; 106(46):
19479-84.
Haga, K., Tomioka, A., Liao, C., Kimura, T., Matsumoto, H., Ohno, I., Hermann, K., Logg, C., Tanaka, M., Hirao, Y., Wu, H., Kruse, C., Roy-Burman, P., and Kasahara N.
PTEN knockout prostate cancer as a model for experimental immunotherapy,
The Journal of Urology,
2009; 181:
354-362.
Gregorian Caroline, Nakashima Jonathan, Le Belle Janel, Ohab John, Kim Rachel, Liu Annie, Smith Kate Barzan, Groszer Matthias, Garcia A Denise, Sofroniew Michael V, Carmichael S Thomas, Kornblum Harley I, Liu Xin, Wu Hong
Pten deletion in adult neural stem/progenitor cells enhances
constitutive neurogenesis
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2009; 29(6):
1874-86.
Couto Suzana S, Cao Mei, Duarte Paulo C, Banach-Petrosky Whitney, Wang Shunyou, Romanienko Peter, Wu Hong, Cardiff Robert D, Abate-Shen Cory, Cunha Gerald R
Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor
genes accelerates tumorigenesis in a mouse model of prostate cancer
Differentiation; research in biological diversity,
2009; 77(1):
103-11.
Guertin David A, Stevens Deanna M, Saitoh Maki, Kinkel Stephanie, Crosby Katherine, Sheen Joon-Ho, Mullholland David J, Magnuson Mark A, Wu Hong, Sabatini David M
mTOR complex 2 is required for the development of prostate cancer
induced by Pten loss in mice
Cancer cell,
2009; 15(2):
148-59.
Majumder Pradip K, Grisanzio Chiara, O'Connell Fionnuala, Barry Marc, Brito Joseph M, Xu Qing, Guney Isil, Berger Raanan, Herman Paula, Bikoff Rachel, Fedele Giuseppe, Baek Won-Ki, Wang Shunyou, Ellwood-Yen Katharine, Wu Hong, Sawyers Charles L, Signoretti Sabina, Hahn William C, Loda Massimo, Sellers William R
A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint
induces senescence and inhibits cell proliferation and cancer
progression
Cancer cell,
2008; 14(2):
146-55.
Burton Jeremy B, Johnson Mai, Sato Makoto, Koh Sok Boon S, Mulholland David J, Stout David, Chatziioannou Arion F, Phelps Michael E, Wu Hong, Wu Lily
Adenovirus-mediated gene expression imaging to directly detect
sentinel lymph node metastasis of prostate cancer
Nature medicine,
2008; 14(8):
882-8.
Degtyarev, M., De Mazière, A., Orr, C., Lin, J., Tien, J., Prior, W., Lee, B., van Dijk, S., Gray, D., Wu, H., Davis, D., Stern, H., Murray, L., Hoeflich, K., Klumperman, J., Friedman, L. and Lin, K.
Akt Inhibition Promotes Autophagy And Sensitizes PTEN-Null Tumors To Late-Stage Autophagy Inhibition,
Journal of Cell Biology,
2008; 186:
101-106.
Mulholland, D.J., Jiao, J. and Wu, H.
Hormone refractory prostate cancer: lesions leaned from the PTEN prostate cancer model,
Adv Exp Med Biol,
2008; 617:
87-95.
Valamehr Bahram, Jonas Steven J, Polleux Julien, Qiao Rong, Guo Shuling, Gschweng Eric H, Stiles Bangyan, Kam Korey, Luo Tzy-Jiun M, Witte Owen N, Liu Xin, Dunn Bruce, Wu Hong
Hydrophobic surfaces for enhanced differentiation of embryonic stem
cell-derived embryoid bodies
Proceedings of the National Academy of Sciences of the United States of America,
2008; 105(38):
14459-64.
Guo Wei, Lasky Joseph L, Chang Chun-Ju, Mosessian Sherly, Lewis Xiaoman, Xiao Yun, Yeh Jennifer E, Chen James Y, Iruela-Arispe M Luisa, Varella-Garcia Marileila, Wu Hong
Multi-genetic events collaboratively contribute to Pten-null leukaemia
stem-cell formation
Nature,
2008; 453(7194):
529-33.
Kwon Chang-Hyuk, Zhao Dawen, Chen Jian, Alcantara Sheila, Li Yanjiao, Burns Dennis K, Mason Ralph P, Lee Eva Y-H P, Wu Hong, Parada Luis F
Pten haploinsufficiency accelerates formation of high-grade
astrocytomas
Cancer research,
2008; 68(9):
3286-94.
Iwanaga, K., Yang, Y., Raso, M., Ma, L., Hanna, A., Thilaganathan N., Moghaddam, S., Evans, C., Li, H., Cai, W., Sato, M., Minna, H., Wu, H., Creighton, C., Demayo, F., Wistuba, I. and Kurie, J.
Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer,
Cancer Research,
2008; 68:
1119-1127.
Vivanco, I., Rohle, D., Versele, M., Palaskas, N., Evans, M., Hsueh, T., Brennan, C., Mulholland, D., Rajasekaran, S., Wolle, D., Rajasekaran, R., Dikic, I., Wu, H., Perera, T. and Mellinghoff, I.K.
Regulation of Epidermal Growth Factor Receptor Signaling by the PTEN Tumor Suppressor,
,
2008; Submitted:
.
Tahk S., Liu, B., Chenishof, V., Wong, K., Wu, H. and Shuai, K.
Control of specificity and magnitude of NF-kB and STAT1-mediated gene activation through PIASy and PIAS1 co-operation
Proceddings of the National Academy of Sciences, USA,
2007; 104(28):
11643-11648.
Memarzadeh, S., Xin, L., Mulholland, D., Mansukhani,A., Wu, H., Teitell,M., and Witte, O.
Enhanced Paracrine FGF10 Expression Promotes Formation of Multifocal Prostate Adenocarcinoma and an Increase in Epithelial Androgen Receptor
Cancer Cell,
2007; 12(6):
572-585.
Shen, W. H., Balajee, A.S., Wang, J., Wu, H., Eng, C., Pandolfi, PP, and Yin, Y.
Essential Role for Nuclear PTEN in Maintaining Chromosomal Integrity,
Cell,
2007; (128):
157-170.
Vivanco, I., Palaskas, N., Tran, C., Finn, S.P., Getz, G., Kennedy, N.G., Jiao, J., Rose, J., Xie, W., Loda, M., Golub, T., Mellinghoff, I., Davis, R., Wu, H. and Sawyers, C.L
Identification of the JNK Signaling Pathway as a Functional Target of the Tumor Suppressor PTEN,
Cancer Cell,
2007; (11):
555-569.
He, X., Zhang, J., Grindley, J.C., Tian, Q., Sato, T., Tao, W.A., Dirisina, R., Porter-Westpfahl, K.S., Hembree, M., Johnson, T., Wiedemann, L., Barrett, T., Hood, L., Wu, H. and Li, L.
Inactivation of PTEN leads to enhanced activation of intestinal stem cells and biasing on lineage fate determination,
Nature Genetics,
2007; (39):
189-198.
Berquin, I.M., Min, Y., Wu, R., Wu, J., Perry, D., Cline, J.M., Thomas, M.J., Thornburg, T., Kulik. G., Smith, A., Edward, I.J., D’Agostino, R., Zhang, H., Wu, H., Kang, J.X., Chen, Y.Q.
Modulation of Prostate Cancer Genetic Risk by Omega-3 and Omega-6 Fatty Acids
Journal of Clinical Investigation,
2007; 117(7):
1866-1875.
Jiao, J., Wang, S., Qiao, R., Vivanco, I., Watson, P., Sawyers, C. and Wu, H.
Murine Cell Lines Derived from Pten Null Prostate Cancer Demonstrate the Critical Role of PTEN in Hormone Refractory Prostate Cancer Development,
Cancer Research,
2007; (67):
6083-6091.
Horvath, S. Zhang, B. Carlson, M. Lu, K. V. Zhu, S. Felciano, R. M. Laurance, M. F. Zhao, W. Qi, S. Chen, Z. Lee, Y. Scheck, A. C. Liau, L. M. Wu, H. Geschwind, D. H. Febbo, P. G. Kornblum, H. I. Cloughesy, T. F. Nelson, S. F. Mischel, P. S.
Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
Proc Natl Acad Sci U S A,
2006; 103(46):
17402-7.
Guo, W. Lasky, J. L., 3rd Wu, H.
Cancer stem cells
Pediatr Res,
2006; 59(4 Pt 2):
59R-64R.
Stiles, B., Kurlawalla-Martinez, C., Guo, W., Tian, J. Wang, Y., and Wu, H.
Deletion of Pten in insulin producing pancreatic -cells leads to increased -cell mass and rescues STZ-induced diabetes,
Molecular Cell Biology,
2006; (26):
2772-2781.
Freeman, D. Lesche, R. Kertesz, N. Wang, S. Li, G. Gao, J. Groszer, M. Martinez-Diaz, H. Rozengurt, N. Thomas, G. Liu, X. Wu, H.
Genetic background controls tumor development in PTEN-deficient mice
Cancer Res,
2006; 66(13):
6492-6.
Khodavirdi, A. C. Song, Z. Yang, S. Zhong, C. Wang, S. Wu, H. Pritchard, C. Nelson, P. S. Roy-Burman, P.
Increased expression of osteopontin contributes to the progression of prostate cancer
Cancer Res,
2006; 66(2):
883-8.
Xu, X. Kobayashi, S. Qiao, W. Li, C. Xiao, C. Radaeva, S. Stiles, B. Wang, R. H. Ohara, N. Yoshino, T. LeRoith, D. Torbenson, M. S. Gores, G. J. Wu, H. Gao, B. Deng, C. X.
Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice
J Clin Invest,
2006; 116(7):
1843-52.
Lei, Q. Jiao, J. Xin, L. Chang, C. J. Wang, S. Gao, J. Gleave, M. E. Witte, O. N. Liu, X. Wu, H.
NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss
Cancer Cell,
2006; 9(5):
367-78.
Li, G. Hu, Y. Huo, Y. Liu, M. Freeman, D. Gao, J. Liu, X. Wu, D. Wu, H.
PTEN deletion leads to up-regulation of a secreted growth factor pleiotrophin
J Biol Chem,
2006;
.
Zhang, J. Grindley, J. C. Yin, T. Jayasinghe, S. He, X. C. Ross, J. T. Haug, J. S. Rupp, D. Porter-Westpfahl, K. S. Wiedemann, L. M. Wu, H. Li, L.
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
Nature,
2006; 441(7092):
518-22.
Groszer M, Erickson R, Scripture-Adams DD, Dougherty JD, Le Belle J, Zack JA, Geschwind DH, Liu X, Kornblum HI, Wu H
PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry
Proc Natl Acad Sci U S A,
2006; 103(1):
111-6.
Wu, H. Khodavirdi, A Roy-Burman, P.
Capturing signal anomalies of human prostate cancer into mouse models,
Prostate cancer: basic mechanisms and therapeutic approaches,
2005;
in press.
Nakano I, Paucar AA, Bajpai R, Dougherty JD, Zewail A, Kelly TK, Kim KJ, Ou J, Groszer M, Imura T, Freije WA, Nelson SF, Sofroniew MV, Wu H, Liu X, Terskikh AV, Geschwind DH, Kornblum HI
Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation
J Cell Biol,
2005; 170(3):
413-27.
Liu B, Yang R, Wong KA, Getman C, Stein N, Cheng G, Wu H, and Shuai K
PIAS1 Participates in the Negative Regulation of NF-kB Signaling,
Mol. Cell Biol,
2005; 25:
1113-23.
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Stanger BZ, Stiles B, Lauwers GY, Bardeesy N, Mendoza M, Wang Y, Greenwood A, Cheng KH, McLaughlin M, Brown D, Depinho RA, Wu H, Melton DA, Dor Y
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas
Cancer cell. ,
2005; 8(3):
185-95.
Stiles B, Wang Y, Stahl A, Bassilian S, Lee WP, Kim YJ, Sherwin R, Devaskar S, Lesche R, Magnuson MA, Wu H
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]
Proc Natl Acad Sci U S A,
2004; 101(7):
2082-7.
Johnson JD, Han Z, Otani K, Ye H, Zhang Y, Wu H, Horikawa Y, Misler S, Bell GI, Polonsky KS
RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets
J Biol Chem,
2004; 279(23):
24794-802.
Freeman DJ, Li AG, Wei G, Li HH, Kertesz N, Lesche R, Whale AD, Martinez-Diaz H, Rozengurt N, Cardiff RD, Liu X, Wu H
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms
Cancer Cell,
2003; 3(2):
117-30.
Wang S, Gao J, Lei Q, Rozengurt N, Pritchard C, Jiao J, Thomas GV, Li G, Roy-Burman P, Nelson PS, Liu X, Wu H
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer
Cancer cell. ,
2003; 4(3):
209-21.
Li G, Robinson GW, Lesche R, Martinez-Diaz H, Jiang Z, Rozengurt N, Wagner KU, Wu DC, Lane TF, Liu X, Hennighausen L, Wu H
Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland
Development,
2002; 129(17):
4159-70.
Osawa M, Yamaguchi T, Nakamura Y, Kaneko S, Onodera M, Sawada K, Jegalian A, Wu H, Nakauchi H, Iwama A
Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis
Blood. ,
2002; 100(8):
2769-77.
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Wong K, Tsai P, Jegalian A, Kertesz N, Lee R and Wu H
Erythropoietin,
In Encyclopedia of Hormones and Related Cell Regulators; ,
2002;
.
Neshat MS, Mellinghoff IK, Tran C, Stiles B, Thomas G, Petersen R, Frost P, Gibbons JJ, Wu H, Sawyers CL
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
Proc Natl Acad Sci U S A,
2001; 98(18):
10314-9.
Hisakawa H, Sugiyama D, Nishijima I, Xu MJ, Wu H, Nakao K, Watanabe S, Katsuki M, Asano S, Arai K, Nakahata T, Tsuji K
Human granulocyte-macrophage colony-stimulating factor (hGM-CSF) stimulates primitive and definitive erythropoiesis in mouse embryos expressing hGM-CSF receptors but not erythropoietin receptors
Blood,
2001; 98(13):
3618-25.
Groszer, M. Erickson, R. Scripture-Adams, D. D. Lesche, R. Trumpp, A. Zack, J. A. Kornblum, H. I. Liu, X. Wu, H.
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo
Science,
2001; 294(5549):
2186-9.
Satterthwaite, A. B. Willis, F. Kanchanastit, P. Fruman, D. Cantley, L. C. Helgason, C. D. Humphries, R. K. Lowell, C. A. Simon, M. Leitges, M. Tarakhovsky, A. Tedder, T. F. Lesche, R. Wu, H. Witte, O. N.
A sensitized genetic system for the analysis of murine B lymphocyte signal transduction pathways dependent on Bruton's tyrosine kinase
Proc Natl Acad Sci U S A,
2000; 97(12):
6687-92.
Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J, Gavrilova N, Mueller B, Liu X, Wu H
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
Proc Natl Acad Sci U S A,
1999; 96(11):
6199-204.
Wu H and Lodish H
The erythropoietin receptor: dimerization and intracellular signal transduction,
Journal of Experimental hematology,
1996; 4:
229-235.
Wu H, Bateman JF, Schnieke A, Sharpe A, Barker D, Mascara T, Eyre D, Bruns R, Krimpenfort P, Berns A
Human-mouse interspecies collagen I heterotrimer is functional during embryonic development of Mov13 mutant mouse embryos
Molecular and cellular biology. ,
1990; 10(4):
1452-60.
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