Publications:
A selected list of publications:
Crandall Carolyn J, Manson JoAnn E, Hohensee Chancellor, Horvath Steve, Wactawski-Wende Jean, LeBlanc Erin S, Vitolins Mara Z, Nassir Rami, Sinsheimer Janet S
Association of genetic variation in the tachykinin receptor 3 locus
with hot flashes and night sweats in the Women's Health Initiative
Study
Menopause (New York, N.Y.),
2017; 24(3):
252-261.
Kozlenkov Alexey, Jaffe Andrew E, Timashpolsky Alisa, Apontes Pasha, Rudchenko Sergei, Barbu Mihaela, Byne William, Hurd Yasmin L, Horvath Steve, Dracheva Stella
DNA Methylation Profiling of Human Prefrontal Cortex Neurons in Heroin
Users Shows Significant Difference between Genomic Contexts of Hyper-
and Hypomethylation and a Younger Epigenetic Age
Genes,
2017; 8(6):
209-219.
Ambatipudi Srikant, Horvath Steve, Perrier Flavie, Cuenin Cyrille, Hernandez-Vargas Hector, Le Calvez-Kelm Florence, Durand Geoffroy, Byrnes Graham, Ferrari Pietro, Bouaoun Liacine, Sklias Athena, Chajes Véronique, Overvad Kim, Severi Gianluca, Baglietto Laura, Clavel-Chapelon Françoise, Kaaks Rudolf, Barrdahl Myrto, Boeing Heiner, Trichopoulou Antonia, Lagiou Pagona, Naska Androniki, Masala Giovanna, Agnoli Claudia, Polidoro Silvia, Tumino Rosario, Panico Salvatore, Dollé Martijn, Peeters Petra H M, Onland-Moret N Charlotte, Sandanger Torkjel M, Nøst Therese H, Weiderpass Elisabete, Quirós J Ramón, Agudo Antonio, Rodriguez-Barranco Miguel, Huerta Castaño José MarÃa, Barricarte Aurelio, Fernández Ander Matheu, Travis Ruth C, Vineis Paolo, Muller David C, Riboli Elio, Gunter Marc, Romieu Isabelle, Herceg Zdenko
DNA methylome analysis identifies accelerated epigenetic ageing
associated with postmenopausal breast cancer susceptibility
European journal of cancer (Oxford, England : 1990),
2017; 75(4):
299-307.
Stölzel Friedrich, Brosch Mario, Horvath Steve, Kramer Michael, Thiede Christian, von Bonin Malte, Ammerpohl Ole, Middeke Moritz, Schetelig Johannes, Ehninger Gerhard, Hampe Jochen, Bornhäuser Martin
Dynamics of epigenetic age following hematopoietic stem cell
transplantation
Haematologica,
2017; 102(8):
e321-e323.
Quach Austin, Levine Morgan E, Tanaka Toshiko, Lu Ake T, Chen Brian H, Ferrucci Luigi, Ritz Beate, Bandinelli Stefania, Neuhouser Marian L, Beasley Jeannette M, Snetselaar Linda, Wallace Robert B, Tsao Philip S, Absher Devin, Assimes Themistocles L, Stewart James D, Li Yun, Hou Lifang, Baccarelli Andrea A, Whitsel Eric A, Horvath Steve
Epigenetic clock analysis of diet, exercise, education, and lifestyle
factors
Aging,
2017; 9(2):
419-446.
Leung Janice M, Fishbane Nick, Jones Meaghan, Morin Alexander, Xu Stella, Liu Joseph Cy, MacIsaac Julie, Milloy M-J, Hayashi Kanna, Montaner Julio, Horvath Steve, Kobor Michael, Sin Don D, Harrigan P Richard, Man S F Paul
Longitudinal study of surrogate aging measures during human
immunodeficiency virus seroconversion
Aging,
2017; 9(3):
687-705.
Simpkin Andrew J, Howe Laura D, Tilling Kate, Gaunt Tom R, Lyttleton Oliver, McArdle Wendy L, Ring Susan M, Horvath Steve, Smith George Davey, Relton Caroline L
The epigenetic clock and physical development during childhood and
adolescence: longitudinal analysis from a UK birth cohort
International journal of epidemiology,
2017; 46(2):
549-558.
Chandran Vijayendran, Coppola Giovanni, Nawabi Homaira, Omura Takao, Versano Revital, Huebner Eric A, Zhang Alice, Costigan Michael, Yekkirala Ajay, Barrett Lee, Blesch Armin, Michaelevski Izhak, Davis-Turak Jeremy, Gao Fuying, Langfelder Peter, Horvath Steve, He Zhigang, Benowitz Larry, Fainzilber Mike, Tuszynski Mark, Woolf Clifford J, Geschwind Daniel H
A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal
Growth Program
Neuron,
2016; 89(5):
956-70.
Levine Andrew J, Quach Austin, Moore David J, Achim Cristian L, Soontornniyomkij Virawudh, Masliah Eliezer, Singer Elyse J, Gelman Benjamin, Nemanim Natasha, Horvath Steve
Accelerated epigenetic aging in brain is associated with pre-mortem
HIV-associated neurocognitive disorders
Journal of neurovirology,
2016; 22(3):
366-75.
Horvath Steve, Gurven Michael, Levine Morgan E, Trumble Benjamin C, Kaplan Hillard, Allayee Hooman, Ritz Beate R, Chen Brian, Lu Ake T, Rickabaugh Tammy M, Jamieson Beth D, Sun Dianjianyi, Li Shengxu, Chen Wei, Quintana-Murci Lluis, Fagny Maud, Kobor Michael S, Tsao Philip S, Reiner Alexander P, Edlefsen Kerstin L, Absher Devin, Assimes Themistocles L
An epigenetic clock analysis of race/ethnicity, sex, and coronary
heart disease
Genome biology,
2016; 17(1):
171.
Knight Anna K, Craig Jeffrey M, Theda Christiane, Bækvad-Hansen Marie, Bybjerg-Grauholm Jonas, Hansen Christine S, Hollegaard Mads V, Hougaard David M, Mortensen Preben B, Weinsheimer Shantel M, Werge Thomas M, Brennan Patricia A, Cubells Joseph F, Newport D Jeffrey, Stowe Zachary N, Cheong Jeanie L Y, Dalach Philippa, Doyle Lex W, Loke Yuk J, Baccarelli Andrea A, Just Allan C, Wright Robert O, Téllez-Rojo Mara M, Svensson Katherine, Trevisi Letizia, Kennedy Elizabeth M, Binder Elisabeth B, Iurato Stella, Czamara Darina, Räikkönen Katri, Lahti Jari M T, Pesonen Anu-Katriina, Kajantie Eero, Villa Pia M, Laivuori Hannele, Hämäläinen Esa, Park Hea Jin, Bailey Lynn B, Parets Sasha E, Kilaru Varun, Menon Ramkumar, Horvath Steve, Bush Nicole R, LeWinn Kaja Z, Tylavsky Frances A, Conneely Karen N, Smith Alicia K
An epigenetic clock for gestational age at birth based on blood
methylation data
Genome biology,
2016; 17(1):
206.
Ligthart Symen, Marzi Carola, Aslibekyan Stella, Mendelson Michael M, Conneely Karen N, Tanaka Toshiko, Colicino Elena, Waite Lindsay L, Joehanes Roby, Guan Weihua, Brody Jennifer A, Elks Cathy, Marioni Riccardo, Jhun Min A, Agha Golareh, Bressler Jan, Ward-Caviness Cavin K, Chen Brian H, Huan Tianxiao, Bakulski Kelly, Salfati Elias L, Salfati Elias L, Fiorito Giovanni, Fiorito Giovanni, Wahl Simone, Schramm Katharina, Sha Jin, Hernandez Dena G, Just Allan C, Smith Jennifer A, Sotoodehnia Nona, Pilling Luke C, Pankow James S, Tsao Phil S, Liu Chunyu, Zhao Wei, Guarrera Simonetta, Michopoulos Vasiliki J, Smith Alicia K, Peters Marjolein J, Melzer David, Vokonas Pantel, Fornage Myriam, Prokisch Holger, Bis Joshua C, Chu Audrey Y, Herder Christian, Grallert Harald, Yao Chen, Shah Sonia, McRae Allan F, Lin Honghuang, Horvath Steve, Fallin Daniele, Hofman Albert, Wareham Nicholas J, Wiggins Kerri L, Feinberg Andrew P, Starr John M, Visscher Peter M, Murabito Joanne M, Kardia Sharon L R, Absher Devin M, Binder Elisabeth B, Singleton Andrew B, Bandinelli Stefania, Peters Annette, Waldenberger Melanie, Matullo Giuseppe, Schwartz Joel D, Demerath Ellen W, Uitterlinden André G, van Meurs Joyce B J, Franco Oscar H, Chen Yii-Der Ida, Levy Daniel, Turner Stephen T, Deary Ian J, Ressler Kerry J, Dupuis Josée, Ferrucci Luigi, Ong Ken K, Assimes Themistocles L, Boerwinkle Eric, Koenig Wolfgang, Arnett Donna K, Baccarelli Andrea A, Benjamin Emelia J, Dehghan Abbas
DNA methylation signatures of chronic low-grade inflammation are
associated with complex diseases
Genome biology,
2016; 17(1):
255.
Chen Brian H, Marioni Riccardo E, Colicino Elena, Peters Marjolein J, Ward-Caviness Cavin K, Tsai Pei-Chien, Roetker Nicholas S, Just Allan C, Demerath Ellen W, Guan Weihua, Bressler Jan, Fornage Myriam, Studenski Stephanie, Vandiver Amy R, Moore Ann Zenobia, Tanaka Toshiko, Kiel Douglas P, Liang Liming, Vokonas Pantel, Schwartz Joel, Lunetta Kathryn L, Murabito Joanne M, Bandinelli Stefania, Hernandez Dena G, Melzer David, Nalls Michael, Pilling Luke C, Price Timothy R, Singleton Andrew B, Gieger Christian, Holle Rolf, Kretschmer Anja, Kronenberg Florian, Kunze Sonja, Linseisen Jakob, Meisinger Christine, Rathmann Wolfgang, Waldenberger Melanie, Visscher Peter M, Shah Sonia, Wray Naomi R, McRae Allan F, Franco Oscar H, Hofman Albert, Uitterlinden André G, Absher Devin, Assimes Themistocles, Levine Morgan E, Lu Ake T, Tsao Philip S, Hou Lifang, Manson JoAnn E, Carty Cara L, LaCroix Andrea Z, Reiner Alexander P, Spector Tim D, Feinberg Andrew P, Levy Daniel, Baccarelli Andrea, van Meurs Joyce, Bell Jordana T, Peters Annette, Deary Ian J, Pankow James S, Ferrucci Luigi, Horvath Steve
DNA methylation-based measures of biological age: meta-analysis
predicting time to death
Aging,
2016; 8(9):
1844-1865.
Lu Ake T, Hannon Eilis, Levine Morgan E, Hao Ke, Crimmins Eileen M, Lunnon Katie, Kozlenkov Alexey, Mill Jonathan, Dracheva Stella, Horvath Steve
Genetic variants near MLST8 and DHX57 affect the epigenetic age of the
cerebellum
Nature communications,
2016; 7(8):
10561.
Parikshak Neelroop N, Swarup Vivek, Belgard T Grant, Irimia Manuel, Ramaswami Gokul, Gandal Michael J, Hartl Christopher, Leppa Virpi, Ubieta Luis de la Torre, Huang Jerry, Lowe Jennifer K, Blencowe Benjamin J, Horvath Steve, Geschwind Daniel H
Genome-wide changes in lncRNA, splicing, and regional gene expression
patterns in autism
Nature,
2016; 540(7633):
423-427.
Horvath Steve, Langfelder Peter, Kwak Seung, Aaronson Jeff, Rosinski Jim, Vogt Thomas F, Eszes Marika, Faull Richard L M, Curtis Maurice A, Waldvogel Henry J, Choi Oi-Wa, Tung Spencer, Vinters Harry V, Coppola Giovanni, Yang X William
Huntington's disease accelerates epigenetic aging of human brain and
disrupts DNA methylation levels
Aging,
2016; 8(7):
1485-512.
Langfelder Peter, Cantle Jeffrey P, Chatzopoulou Doxa, Wang Nan, Gao Fuying, Al-Ramahi Ismael, Lu Xiao-Hong, Ramos Eliana Marisa, El-Zein Karla, Zhao Yining, Deverasetty Sandeep, Tebbe Andreas, Schaab Christoph, Lavery Daniel J, Howland David, Kwak Seung, Botas Juan, Aaronson Jeffrey S, Rosinski Jim, Coppola Giovanni, Horvath Steve, Yang X William
Integrated genomics and proteomics define huntingtin CAG
length-dependent networks in mice
Nature neuroscience,
2016; 19(4):
623-33.
Liu Xian, Grogan Tristan R, Hieronymus Haley, Hashimoto Takao, Mottahedeh Jack, Cheng Donghui, Zhang Lijun, Huang Kevin, Stoyanova Tanya, Park Jung Wook, Shkhyan Ruzanna O, Nowroozizadeh Behdokht, Rettig Matthew B, Sawyers Charles L, Elashoff David, Horvath Steve, Huang Jiaoti, Witte Owen N, Goldstein Andrew S
Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal
Cells that Can Initiate Human Prostate Cancer and Predict Poor
Outcome
Cell reports,
2016; 17(10):
2596-2606.
Hong Candice Sun, Graham Nicholas A, Gu Wen, Espindola Camacho Carolina, Mah Vei, Maresh Erin L, Alavi Mohammed, Bagryanova Lora, Krotee Pascal A L, Gardner Brian K, Behbahan Iman Saramipoor, Horvath Steve, Chia David, Mellinghoff Ingo K, Hurvitz Sara A, Dubinett Steven M, Critchlow Susan E, Kurdistani Siavash K, Goodglick Lee, Braas Daniel, Graeber Thomas G, Christofk Heather R
MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that
Co-express MCT1 and MCT4
Cell reports,
2016; 14(7):
1590-601.
Levine Morgan E, Lu Ake T, Chen Brian H, Hernandez Dena G, Singleton Andrew B, Ferrucci Luigi, Bandinelli Stefania, Salfati Elias, Manson JoAnn E, Quach Austin, Kusters Cynthia D J, Kuh Diana, Wong Andrew, Teschendorff Andrew E, Widschwendter Martin, Ritz Beate R, Absher Devin, Assimes Themistocles L, Horvath Steve
Menopause accelerates biological aging
Proceedings of the National Academy of Sciences of the United States of America,
2016; 113(33):
9327-32.
Li Xiaoxiao, LeBlanc James, Elashoff David, McHardy Ian, Tong Maomeng, Roth Bennett, Ippoliti Andrew, Barron Gildardo, McGovern Dermot, McDonald Keely, Newberry Rodney, Graeber Thomas, Horvath Steve, Goodglick Lee, Braun Jonathan
Microgeographic Proteomic Networks of the Human Colonic Mucosa and
Their Association With Inflammatory Bowel Disease
Cellular and molecular gastroenterology and hepatology,
2016; 2(5):
567-583.
Simpkin Andrew J, Hemani Gibran, Suderman Matthew, Gaunt Tom R, Lyttleton Oliver, Mcardle Wendy L, Ring Susan M, Sharp Gemma C, Tilling Kate, Horvath Steve, Kunze Sonja, Peters Annette, Waldenberger Melanie, Ward-Caviness Cavin, Nohr Ellen A, Sørensen Thorkild I A, Relton Caroline L, Smith George Davey
Prenatal and early life influences on epigenetic age in children: a
study of mother-offspring pairs from two cohort studies
Human molecular genetics,
2016; 25(1):
191-201.
Vidal-Bralo Laura, Lopez-Golan Yolanda, Mera-Varela Antonio, Rego-Perez Ignacio, Horvath Steve, Zhang Yuhua, Del Real Ãlvaro, Zhai Guangju, Blanco Francisco J, Riancho Jose A, Gomez-Reino Juan J, Gonzalez Antonio
Specific premature epigenetic aging of cartilage in osteoarthritis
Aging,
2016; 8(9):
2222-2231.
Horvath Steve, Garagnani Paolo, Bacalini Maria Giulia, Pirazzini Chiara, Salvioli Stefano, Gentilini Davide, Di Blasio Anna Maria, Giuliani Cristina, Tung Spencer, Vinters Harry V, Franceschi Claudio
Accelerated epigenetic aging in Down syndrome
Aging cell,
2015; 14(3):
491-5.
Rickabaugh Tammy M, Baxter Ruth M, Sehl Mary, Sinsheimer Janet S, Hultin Patricia M, Hultin Lance E, Quach Austin, MartÃnez-Maza Otoniel, Horvath Steve, Vilain Eric, Jamieson Beth D
Acceleration of age-associated methylation patterns in HIV-1-infected
adults
PloS one,
2015; 10(3):
e0119201.
Marioni Riccardo E, Shah Sonia, McRae Allan F, Chen Brian H, Colicino Elena, Harris Sarah E, Gibson Jude, Henders Anjali K, Redmond Paul, Cox Simon R, Pattie Alison, Corley Janie, Murphy Lee, Martin Nicholas G, Montgomery Grant W, Feinberg Andrew P, Fallin M Daniele, Multhaup Michael L, Jaffe Andrew E, Joehanes Roby, Schwartz Joel, Just Allan C, Lunetta Kathryn L, Murabito Joanne M, Starr John M, Horvath Steve, Baccarelli Andrea A, Levy Daniel, Visscher Peter M, Wray Naomi R, Deary Ian J
DNA methylation age of blood predicts all-cause mortality in later
life
Genome biology,
2015; 16(3):
25.
Horvath Steve, Pirazzini Chiara, Bacalini Maria Giulia, Gentilini Davide, Di Blasio Anna Maria, Delledonne Massimo, Mari Daniela, Arosio Beatrice, Monti Daniela, Passarino Giuseppe, De Rango Francesco, D'Aquila Patrizia, Giuliani Cristina, Marasco Elena, Collino Sebastiano, Descombes Patrick, Garagnani Paolo, Franceschi Claudio
Decreased epigenetic age of PBMCs from Italian semi-supercentenarians
and their offspring
Aging,
2015; 7(12):
1159-70.
Boks Marco P, van Mierlo Hans C, Rutten Bart P F, Radstake Timothy R D J, De Witte Lot, Geuze Elbert, Horvath Steve, Schalkwyk Leonard C, Vinkers Christiaan H, Broen Jasper C A, Vermetten Eric
Longitudinal changes of telomere length and epigenetic age related to
traumatic stress and post-traumatic stress disorder
Psychoneuroendocrinology,
2015; 51(3):
506-12.
Mah Vei, Alavi Mohammad, Márquez-Garbán Diana C, Maresh Erin L, Kim Sara R, Horvath Steve, Bagryanova Lora, Huerta-Yepez Sara, Chia David, Pietras Richard, Goodglick Lee
Ribonucleotide reductase subunit M2 predicts survival in subgroups of
patients with non-small cell lung carcinoma: effects of gender and
smoking status
PloS one,
2015; 10(5):
e0127600.
Luo Yuping, Coskun Volkan, Liang Aibing, Yu Juehua, Cheng Liming, Ge Weihong, Shi Zhanping, Zhang Kunshan, Li Chun, Cui Yaru, Lin Haijun, Luo Dandan, Wang Junbang, Lin Connie, Dai Zachary, Zhu Hongwen, Zhang Jun, Liu Jie, Liu Hailiang, deVellis Jean, Horvath Steve, Sun Yi Eve, Li Siguang
Single-cell transcriptome analyses reveal signals to activate dormant
neural stem cells
Cell,
2015; 161(5):
1175-86.
Horvath Steve, Mah Vei, Lu Ake T, Woo Jennifer S, Choi Oi-Wa, Jasinska Anna J, Riancho José A, Tung Spencer, Coles Natalie S, Braun Jonathan, Vinters Harry V, Coles L Stephen
The cerebellum ages slowly according to the epigenetic clock
Aging,
2015; 7(5):
294-306.
Marioni Riccardo E, Shah Sonia, McRae Allan F, Ritchie Stuart J, Muniz-Terrera Graciela, Harris Sarah E, Gibson Jude, Redmond Paul, Cox Simon R, Pattie Alison, Corley Janie, Taylor Adele, Murphy Lee, Starr John M, Horvath Steve, Visscher Peter M, Wray Naomi R, Deary Ian J
The epigenetic clock is correlated with physical and cognitive fitness
in the Lothian Birth Cohort 1936
International journal of epidemiology,
2015; 44(4):
1388-96.
Duan Hongmei, Ge Weihong, Zhang Aifeng, Xi Yue, Chen Zhihua, Luo Dandan, Cheng Yin, Fan Kevin S, Horvath Steve, Sofroniew Michael V, Cheng Liming, Yang Zhaoyang, Sun Yi E, Li Xiaoguang
Transcriptome analyses reveal molecular mechanisms underlying
functional recovery after spinal cord injury
Proceedings of the National Academy of Sciences of the United States of America,
2015; 112(43):
13360-5.
Li Yun, Chen Jason A, Sears Renee L, Gao Fuying, Klein Eric D, Karydas Anna, Geschwind Michael D, Rosen Howard J, Boxer Adam L, Guo Weilong, Pellegrini Matteo, Horvath Steve, Miller Bruce L, Geschwind Daniel H, Coppola Giovanni
An epigenetic signature in peripheral blood associated with the
haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy
PLoS genetics,
2014; 10(3):
e1004211.
Khalid Omar, Kim Jeffrey J, Kim Hyun-Sung, Hoang Michael, Tu Thanh G, Elie Omid, Lee Connie, Vu Catherine, Horvath Steve, Spigelman Igor, Kim Yong
Gene expression signatures affected by alcohol-induced DNA methylomic
deregulation in human embryonic stem cells
Stem cell research,
2014; 12(3):
791-806.
Montoya Dennis, Inkeles Megan S, Liu Phillip T, Realegeno Susan, Teles Rosane M B, Vaidya Poorva, Munoz Marcos A, Schenk Mirjam, Swindell William R, Chun Rene, Zavala Kathryn, Hewison Martin, Adams John S, Horvath Steve, Pellegrini Matteo, Bloom Barry R, Modlin Robert L
IL-32 is a molecular marker of a host defense network in human
tuberculosis
Science translational medicine,
2014; 6(250):
250ra114.
Horvath Steve, Erhart Wiebke, Brosch Mario, Ammerpohl Ole, von Schönfels Witigo, Ahrens Markus, Heits Nils, Bell Jordana T, Tsai Pei-Chien, Spector Tim D, Deloukas Panos, Siebert Reiner, Sipos Bence, Becker Thomas, Röcken Christoph, Schafmayer Clemens, Hampe Jochen
Obesity accelerates epigenetic aging of human liver
Proceedings of the National Academy of Sciences of the United States of America,
2014; 111(43):
15538-43.
Corominas Roser, Yang Xinping, Lin Guan Ning, Kang Shuli, Shen Yun, Ghamsari Lila, Broly Martin, Rodriguez Maria, Tam Stanley, Trigg Shelly A, Fan Changyu, Yi Song, Tasan Murat, Lemmens Irma, Kuang Xingyan, Zhao Nan, Malhotra Dheeraj, Michaelson Jacob J, Vacic Vladimir, Calderwood Michael A, Roth Frederick P, Tavernier Jan, Horvath Steve, Salehi-Ashtiani Kourosh, Korkin Dmitry, Sebat Jonathan, Hill David E, Hao Tong, Vidal Marc, Iakoucheva Lilia M
Protein interaction network of alternatively spliced isoforms from
brain links genetic risk factors for autism
Nature communications,
2014; 5(3):
3650.
De Jong Simone, Neeleman Marjolein, Luykx Jurjen J, ten Berg Maarten J, Strengman Eric, Den Breeijen Hanneke H, Stijvers Leon C, Buizer-Voskamp Jacobine E, Bakker Steven C, Kahn René S, Horvath Steve, Van Solinge Wouter W, Ophoff Roel A
Seasonal changes in gene expression represent cell-type composition in
whole blood
Human molecular genetics,
2014; 23(10):
2721-8.
Tong Maomeng, Li Xiaoxiao, Wegener Parfrey Laura, Roth Bennett, Ippoliti Andrew, Wei Bo, Borneman James, McGovern Dermot P B, Frank Daniel N, Li Ellen, Horvath Steve, Knight Rob, Braun Jonathan
A modular organization of the human intestinal mucosal microbiota and
its association with inflammatory bowel disease
PloS one,
2013; 8(11):
e80702.
Xue Zhigang, Huang Kevin, Cai Chaochao, Cai Lingbo, Jiang Chun-yan, Feng Yun, Liu Zhenshan, Zeng Qiao, Cheng Liming, Sun Yi E, Liu Jia-yin, Horvath Steve, Fan Guoping
Genetic programs in human and mouse early embryos revealed by
single-cell RNA sequencing
Nature,
2013; 500(7464):
593-7.
McHardy Ian H, Goudarzi Maryam, Tong Maomeng, Ruegger Paul M, Schwager Emma, Weger John R, Graeber Thomas G, Sonnenburg Justin L, Horvath Steve, Huttenhower Curtis, McGovern Dermot Pb, Fornace Albert J, Borneman James, Braun Jonathan
Integrative analysis of the microbiome and metabolome of the human
intestinal mucosal surface reveals exquisite inter-relationships
Microbiome,
2013; 1(1):
17.
Ho Melissa E, Quek Sue-Ing, True Lawrence D, Morrissey Colm, Corey Eva, Vessella Robert L, Dumpit Ruth, Nelson Peter S, Maresh Erin L, Mah Vei, Alavi Mohammed, Kim Sara R, Bagryanova Lora, Horvath Steve, Chia David, Goodglick Lee, Liu Alvin Y
Prostate cancer cell phenotypes based on AGR2 and CD10 expression
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc,
2013; 26(6):
849-59.
Levine Andrew J, Miller Jeremy A, Shapshak Paul, Gelman Benjamin, Singer Elyse J, Hinkin Charles H, Commins Deborah, Morgello Susan, Grant Igor, Horvath Steve
Systems analysis of human brain gene expression: mechanisms for
HIV-associated neurocognitive impairment and common pathways with
Alzheimer's disease
BMC medical genomics,
2013; 6(4):
4.
Weiss James N, Karma Alain, MacLellan W Robb, Deng Mario, Rau Christoph D, Rees Colin M, Wang Jessica, Wisniewski Nicholas, Eskin Eleazar, Horvath Steve, Qu Zhilin, Wang Yibin, Lusis Aldons J
"Good enough solutions" and the genetics of complex diseases
Circulation research,
2012; 111(4):
493-504.
de Jong Simone, Boks Marco P M, Fuller Tova F, Strengman Eric, Janson Esther, de Kovel Carolien G F, Ori Anil P S, Vi Nancy, Mulder Flip, Blom Jan Dirk, Glenthøj Birte, Schubart Chris D, Cahn Wiepke, Kahn René S, Horvath Steve, Ophoff Roel A
A gene co-expression network in whole blood of schizophrenia patients
is independent of antipsychotic-use and enriched for brain-expressed
genes
PloS one,
2012; 7(6):
e39498.
Haas Blake E, Horvath Steve, Pietiläinen Kirsi H, Cantor Rita M, Nikkola Elina, Weissglas-Volkov Daphna, Rissanen Aila, Civelek Mete, Cruz-Bautista Ivette, Riba Laura, Kuusisto Johanna, Kaprio Jaakko, Tusie-Luna Teresa, Laakso Markku, Aguilar-Salinas Carlos A, Pajukanta Päivi
Adipose co-expression networks across Finns and Mexicans identify
novel triglyceride-associated genes
BMC medical genomics,
2012; 5(4):
61.
Hawrylycz Michael J, Lein Ed S, Guillozet-Bongaarts Angela L, Shen Elaine H, Ng Lydia, Miller Jeremy A, van de Lagemaat Louie N, Smith Kimberly A, Ebbert Amanda, Riley Zackery L, Abajian Chris, Beckmann Christian F, Bernard Amy, Bertagnolli Darren, Boe Andrew F, Cartagena Preston M, Chakravarty M Mallar, Chapin Mike, Chong Jimmy, Dalley Rachel A, Daly Barry David, Dang Chinh, Datta Suvro, Dee Nick, Dolbeare Tim A, Faber Vance, Feng David, Fowler David R, Goldy Jeff, Gregor Benjamin W, Haradon Zeb, Haynor David R, Hohmann John G, Horvath Steve, Howard Robert E, Jeromin Andreas, Jochim Jayson M, Kinnunen Marty, Lau Christopher, Lazarz Evan T, Lee Changkyu, Lemon Tracy A, Li Ling, Li Yang, Morris John A, Overly Caroline C, Parker Patrick D, Parry Sheana E, Reding Melissa, Royall Joshua J, Schulkin Jay, Sequeira Pedro Adolfo, Slaughterbeck Clifford R, Smith Simon C, Sodt Andy J, Sunkin Susan M, Swanson Beryl E, Vawter Marquis P, Williams Derric, Wohnoutka Paul, Zielke H Ronald, Geschwind Daniel H, Hof Patrick R, Smith Stephen M, Koch Christof, Grant Seth G N, Jones Allan R
An anatomically comprehensive atlas of the adult human brain
transcriptome
Nature,
2012; 489(7416):
391-9.
Vivanco Igor, Robins H Ian, Rohle Daniel, Campos Carl, Grommes Christian, Nghiemphu Phioanh Leia, Kubek Sara, Oldrini Barbara, Chheda Milan G, Yannuzzi Nicolas, Tao Hui, Zhu Shaojun, Iwanami Akio, Kuga Daisuke, Dang Julie, Pedraza Alicia, Brennan Cameron W, Heguy Adriana, Liau Linda M, Lieberman Frank, Yung W K Alfred, Gilbert Mark R, Reardon David A, Drappatz Jan, Wen Patrick Y, Lamborn Kathleen R, Chang Susan M, Prados Michael D, Fine Howard A, Horvath Steve, Wu Nian, Lassman Andrew B, DeAngelis Lisa M, Yong William H, Kuhn John G, Mischel Paul S, Mehta Minesh P, Cloughesy Timothy F, Mellinghoff Ingo K
Differential sensitivity of glioma- versus lung cancer-specific EGFR
mutations to EGFR kinase inhibitors
Cancer discovery,
2012; 2(5):
458-71.
van Eijk Kristel R, de Jong Simone, Boks Marco P M, Langeveld Terry, Colas Fabrice, Veldink Jan H, de Kovel Carolien G F, Janson Esther, Strengman Eric, Langfelder Peter, Kahn René S, van den Berg Leonard H, Horvath Steve, Ophoff Roel A
Genetic analysis of DNA methylation and gene expression levels in
whole blood of healthy human subjects
BMC genomics,
2012; 13(4):
636.
Diekstra Frank P, Saris Christiaan G J, van Rheenen Wouter, Franke Lude, Jansen Ritsert C, van Es Michael A, van Vught Paul W J, Blauw Hylke M, Groen Ewout J N, Horvath Steve, Estrada Karol, Rivadeneira Fernando, Hofman Albert, Uitterlinden Andre G, Robberecht Wim, Andersen Peter M, Melki Judith, Meininger Vincent, Hardiman Orla, Landers John E, Brown Robert H, Shatunov Aleksey, Shaw Christopher E, Leigh P Nigel, Al-Chalabi Ammar, Ophoff Roel A, van den Berg Leonard H, Veldink Jan H
Mapping of gene expression reveals CYP27A1 as a susceptibility gene
for sporadic ALS
PloS one,
2012; 7(4):
e35333.
Huynh Thu P, Mah Vei, Sampson Valerie B, Chia David, Fishbein Michael C, Horvath Steve, Alavi Mohammad, Wu Debbie C, Harper Jeffrey, Sarafian Ted, Dubinett Steven M, Langhans Sigrid A, Goodglick Lee, Rajasekaran Ayyappan K
Na,K-ATPase is a target of cigarette smoke and reduced expression
predicts poor patient outcome of smokers with lung cancer
American journal of physiology. Lung cellular and molecular physiology,
2012; 302(11):
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Shirasaki Dyna I, Greiner Erin R, Al-Ramahi Ismael, Gray Michelle, Boontheung Pinmanee, Geschwind Daniel H, Botas Juan, Coppola Giovanni, Horvath Steve, Loo Joseph A, Yang X William
Network organization of the huntingtin proteomic interactome in
mammalian brain
Neuron,
2012; 75(1):
41-57.
Luykx Jurjen J, Bakker Steven C, Lentjes Eef, Boks Marco P M, van Geloven Nan, Eijkemans Marinus J C, Janson Esther, Strengman Eric, de Lepper Anne M, Westenberg Herman, Klopper Kai E, Hoorn Hendrik J, Gelissen Harry P M M, Jordan Julian, Tolenaar Noortje M, van Dongen Eric P A, Michel Bregt, Abramovic Lucija, Horvath Steve, Kappen Teus, Bruins Peter, Keijzers Peter, Borgdorff Paul, Ophoff Roel A, Kahn René S
Season of sampling and season of birth influence serotonin metabolite
levels in human cerebrospinal fluid
PloS one,
2012; 7(2):
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Horvath Steve, Nazmul-Hossain Abu Nm, Pollard Rodney Pe, Kroese Frans Gm, Vissink Arjan, Kallenberg Cees Gm, Spijkervet Fred Kl, Bootsma Hendrika, Michie Sara A, Gorr Sven U, Peck Ammon B, Cai Chaochao, Zhou Hui, Wong David Tw
Systems analysis of primary Sjögren's syndrome pathogenesis in
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Arthritis research & therapy,
2012; 14(6):
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Bocklandt Sven, Lin Wen, Sehl Mary E, Sánchez Francisco J, Sinsheimer Janet S, Horvath Steve, Vilain Eric
Epigenetic predictor of age
PloS one,
2011; 6(6):
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Mah Vei, Marquez Diana, Alavi Mohammad, Maresh Erin L, Zhang Li, Yoon Nam, Horvath Steve, Bagryanova Lora, Fishbein Michael C, Chia David, Pietras Richard, Goodglick Lee
Expression levels of estrogen receptor beta in conjunction with
aromatase predict survival in non-small cell lung cancer
Lung cancer (Amsterdam, Netherlands),
2011; 474(7351):
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Huerta-Yepez Sara, Yoon Nam K, Hernandez-Cueto Angeles, Mah Vei, Rivera-Pazos Clara M, Chatterjee Devasis, Vega Mario I, Maresh Erin L, Horvath Steve, Chia David, Bonavida Benjamin, Goodglick Lee
Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a
predictor of lung cancer survival
BMC cancer,
2011; 11(9):
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Dewey Frederick E, Perez Marco V, Wheeler Matthew T, Watt Clifton, Spin Joshua, Langfelder Peter, Horvath Steve, Hannenhalli Sridhar, Cappola Thomas P, Ashley Euan A
Gene coexpression network topology of cardiac development,
hypertrophy, and failure
Circulation. Cardiovascular genetics,
2011; 4(1):
26-35.
Park Christopher C, Gale Greg D, de Jong Simone, Ghazalpour Anatole, Bennett Brian J, Farber Charles R, Langfelder Peter, Lin Andy, Khan Arshad H, Eskin Eleazar, Horvath Steve, Lusis Aldons J, Ophoff Roel A, Smith Desmond J
Gene networks associated with conditional fear in mice identified
using a systems genetics approach
BMC systems biology,
2011; 5(7351):
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Marquez-Garban Diana C, Mah Vei, Alavi Mohammad, Maresh Erin L, Chen Hsiao-Wang, Bagryanova Lora, Horvath Steve, Chia David, Garon Edward, Goodglick Lee, Pietras Richard J
Progesterone and estrogen receptor expression and activity in human
non-small cell lung cancer
Steroids,
2011; 76(9):
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Presson Angela P, Yoon Nam K, Bagryanova Lora, Mah Vei, Alavi Mohammad, Maresh Erin L, Rajasekaran Ayyappan K, Goodglick Lee, Chia David, Horvath Steve
Protein expression based multimarker analysis of breast cancer
samples
BMC cancer,
2011; 11(9):
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Voineagu Irina, Wang Xinchen, Johnston Patrick, Lowe Jennifer K, Tian Yuan, Horvath Steve, Mill Jonathan, Cantor Rita M, Blencowe Benjamin J, Geschwind Daniel H
Transcriptomic analysis of autistic brain reveals convergent molecular
pathology
Nature,
2011; 474(7351):
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Manuyakorn Ananya, Paulus Rebecca, Farrell James, Dawson Nicole A, Tze Sheila, Cheung-Lau Gardenia, Hines Oscar Joe, Reber Howard, Seligson David B, Horvath Steve, Kurdistani Siavash K, Guha Chandhan, Dawson David W
Cellular histone modification patterns predict prognosis and treatment
response in resectable pancreatic adenocarcinoma: results from RTOG
9704
Journal of clinical oncology : official journal of the American Society of Clinical Oncology,
2010; 28(8):
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Maresh Erin L, Mah Vei, Alavi Mohammad, Horvath Steve, Bagryanova Lora, Liebeskind Emily S, Knutzen Laura A, Zhou Yong, Chia David, Liu Alvin Y, Goodglick Lee
Differential expression of anterior gradient gene AGR2 in prostate
cancer
BMC cancer,
2010; 10(6):
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Habeeb Omar, Goodglick Lee, Soslow Robert A, Rao Rajiv G, Gordon Lynn K, Schirripa Osvaldo, Horvath Steve, Braun Jonathan, Seligson David B, Wadehra Madhuri
Epithelial membrane protein-2 expression is an early predictor of
endometrial cancer development
Cancer,
2010; 116(20):
4718-26.
Le Brandon H, Cheng Chen, Bui Anhthu Q, Wagmaister Javier A, Henry Kelli F, Pelletier Julie, Kwong Linda, Belmonte Mark, Kirkbride Ryan, Horvath Steve, Drews Gary N, Fischer Robert L, Okamuro Jack K, Harada John J, Goldberg Robert B
Global analysis of gene activity during Arabidopsis seed development
and identification of seed-specific transcription factors
Proceedings of the National Academy of Sciences of the United States of America,
2010; 107(18):
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Yoon Nam K, Maresh Erin L, Shen Dejun, Elshimali Yahya, Apple Sophia, Horvath Steve, Mah Vei, Bose Shikha, Chia David, Chang Helena R, Goodglick Lee
Higher levels of GATA3 predict better survival in women with breast
cancer
Human pathology,
2010; 41(12):
1794-801.
Ooi Aik T, Mah Vei, Nickerson Derek W, Gilbert Jennifer L, Ha Vi Luan, Hegab Ahmed E, Horvath Steve, Alavi Mohammad, Maresh Erin L, Chia David, Gower Adam C, Lenburg Marc E, Spira Avrum, Solis Luisa M, Wistuba Ignacio I, Walser Tonya C, Wallace William D, Dubinett Steven M, Goodglick Lee, Gomperts Brigitte N
Presence of a putative tumor-initiating progenitor cell population
predicts poor prognosis in smokers with non-small cell lung cancer
Cancer research,
2010; 70(16):
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Plaisier Christopher L, Horvath Steve, Huertas-Vazquez Adriana, Cruz-Bautista Ivette, Herrera Miguel F, Tusie-Luna Teresa, Aguilar-Salinas Carlos, Pajukanta Päivi
A systems genetics approach implicates USF1, FADS3, and other causal
candidate genes for familial combined hyperlipidemia
PLoS genetics,
2009; 5(9):
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Farber Charles R, van Nas Atila, Ghazalpour Anatole, Aten Jason E, Doss Sudheer, Sos Brandon, Schadt Eric E, Ingram-Drake Leslie, Davis Richard C, Horvath Steve, Smith Desmond J, Drake Thomas A, Lusis Aldons J
An integrative genetics approach to identify candidate genes
regulating BMD: combining linkage, gene expression, and association
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
2009; 24(1):
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Kurian Sunil M, Heilman Raymond, Mondala Tony S, Nakorchevsky Aleksey, Hewel Johannes A, Campbell Daniel, Robison Elizabeth H, Wang Lin, Lin Wen, Gaber Lillian, Solez Kim, Shidban Hamid, Mendez Robert, Schaffer Randolph L, Fisher Jonathan S, Flechner Stuart M, Head Steve R, Horvath Steve, Yates John R, Marsh Christopher L, Salomon Daniel R
Biomarkers for early and late stage chronic allograft nephropathy by
proteogenomic profiling of peripheral blood
PloS one,
2009; 4(7):
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Kleefuss-Lie Ailing, Friedl Waltraut, Cichon Sven, Haug Karsten, Warnstedt Maike, Alekov Alexi, Sander Thomas, Ramirez Alfredo, Poser Barbara, Maljevic Snezana, Hebeisen Simon, Kubisch Christian, Rebstock Johannes, Horvath Steve, Hallmann Kerstin, Dullinger Jörn S, Rau Birgit, Haverkamp Fritz, Beyenburg Stefan, Schulz Herbert, Janz Dieter, Giese Bernd, Müller-Newen Gerhard, Propping Peter, Elger Christian E, Fahlke Christoph, Lerche Holger
CLCN2 variants in idiopathic generalized epilepsy
Nature genetics,
2009; 41(9):
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Guo Deliang, Prins Robert M, Dang Julie, Kuga Daisuke, Iwanami Akio, Soto Horacio, Lin Kelly Y, Huang Tiffany T, Akhavan David, Hock M Benjamin, Zhu Shaojun, Kofman Ava A, Bensinger Steve J, Yong William H, Vinters Harry V, Horvath Steve, Watson Andrew D, Kuhn John G, Robins H Ian, Mehta Minesh P, Wen Patrick Y, DeAngelis Lisa M, Prados Michael D, Mellinghoff Ingo K, Cloughesy Timothy F, Mischel Paul S
EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant
pathway sensitizes glioblastomas to antilipogenic therapy
Science signaling,
2009; 2(101):
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van Nas Atila, Guhathakurta Debraj, Wang Susanna S, Yehya Nadir, Horvath Steve, Zhang Bin, Ingram-Drake Leslie, Chaudhuri Gautam, Schadt Eric E, Drake Thomas A, Arnold Arthur P, Lusis Aldons J
Elucidating the role of gonadal hormones in sexually dimorphic gene
coexpression networks
Endocrinology,
2009; 150(3):
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Farber Charles R, Aten Jason E, Farber Emily A, de Vera Vincent, Gularte Rodrigo, Islas-Trejo Alma, Wen Pengzi, Horvath Steve, Lucero Michael, Lusis Aldons J, Medrano Juan F
Genetic dissection of a major mouse obesity QTL (Carfhg2): integration
of gene expression and causality modeling
Physiological genomics,
2009; 37(3):
294-302.
Seligson David B, Horvath Steve, McBrian Matthew A, Mah Vei, Yu Hong, Tze Sheila, Wang Qun, Chia David, Goodglick Lee, Kurdistani Siavash K
Global levels of histone modifications predict prognosis in different
cancers
The American journal of pathology,
2009; 174(5):
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Yoon Nam K, Seligson David B, Chia David, Elshimali Yahya, Sulur Giri, Li Ai, Horvath Steve, Maresh Erin, Mah Vei, Bose Shikha, Bonavida Benjamin, Goodglick Lee
Higher expression levels of 14-3-3sigma in ductal carcinoma in situ of
the breast predict poorer outcome
Cancer biomarkers : section A of Disease markers,
2009; 5(4):
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Laks Dan R, Masterman-Smith Michael, Visnyei Koppany, Angenieux Brigitte, Orozco Nicholas M, Foran Ian, Yong William H, Vinters Harry V, Liau Linda M, Lazareff Jorge A, Mischel Paul S, Cloughesy Timothy F, Horvath Steve, Kornblum Harley I
Neurosphere formation is an independent predictor of clinical outcome
in malignant glioma
Stem cells (Dayton, Ohio),
2009; 27(4):
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Haug Karsten, Warnstedt Maike, Alekov Alexi K, Sander Thomas, RamÃrez Alfredo, Poser Barbara, Maljevic Snezana, Hebeisen Simon, Kubisch Christian, Rebstock Johannes, Horvath Steve, Hallmann Kerstin, Dullinger Joern S, Rau Birgit, Haverkamp Fritz, Beyenburg Stefan, Schulz Herbert, Janz Dieter, Giese Bernd, Müller-Newen Gerhard, Propping Peter, Elger Christian E, Fahlke Christoph, Lerche Holger
Retraction: Mutations in CLCN2 encoding a voltage-gated chloride
channel are associated with idiopathic generalized epilepsies
Nature genetics,
2009; 41(9):
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Hu Shen, Zhou Michael, Jiang Jiang, Wang Jianghua, Elashoff David, Gorr Sven, Michie Sara A, Spijkervet Fred K L, Bootsma Hendrika, Kallenberg Cees G M, Vissink Arjan, Horvath Steve, Wong David T
Systems biology analysis of Sjögren's syndrome and mucosa-associated
lymphoid tissue lymphoma in parotid glands
Arthritis and rheumatism,
2009; 60(1):
81-92.
Saris Christiaan G J, Horvath Steve, van Vught Paul W J, van Es Michael A, Blauw Hylke M, Fuller Tova F, Langfelder Peter, DeYoung Joseph, Wokke John H J, Veldink Jan H, van den Berg Leonard H, Ophoff Roel A
Weighted gene co-expression network analysis of the peripheral blood
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BMC genomics,
2009; 10(9):
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Cloughesy Tim F, Yoshimoto Koji, Nghiemphu Phioanh, Brown Kevin, Dang Julie, Zhu Shaojun, Hsueh Teli, Chen Yinan, Wang Wei, Youngkin David, Liau Linda, Martin Neil, Becker Don, Bergsneider Marvin, Lai Albert, Green Richard, Oglesby Tom, Koleto Michael, Trent Jeff, Horvath Steve, Mischel Paul S, Mellinghoff Ingo K, Sawyers Charles L
Antitumor activity of rapamycin in a Phase I trial for patients with
recurrent PTEN-deficient glioblastoma
PLoS medicine,
2008; 5(1):
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Yoshimoto Koji, Dang Julie, Zhu Shaojun, Nathanson David, Huang Tiffany, Dumont Rebecca, Seligson David B, Yong William H, Xiong Zhenggang, Rao Nagesh, Winther Henrik, Chakravarti Arnab, Bigner Darell D, Mellinghoff Ingo K, Horvath Steve, Cavenee Webster K, Cloughesy Timothy F, Mischel Paul S
Development of a real-time RT-PCR assay for detecting EGFRvIII in
glioblastoma samples
Clinical cancer research : an official journal of the American Association for Cancer Research,
2008; 14(2):
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Lee Yohan, Scheck Adrienne C, Cloughesy Timothy F, Lai Albert, Dong Jun, Farooqi Haumith K, Liau Linda M, Horvath Steve, Mischel Paul S, Nelson Stanley F
Gene expression analysis of glioblastomas identifies the major
molecular basis for the prognostic benefit of younger age
BMC medical genomics,
2008; 1(11):
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Nakano Ichiro, Masterman-Smith Michael, Saigusa Kuniyasu, Paucar Andres A, Horvath Steve, Shoemaker Lorelei, Watanabe Momoko, Negro Alejandra, Bajpai Ruchi, Howes Amy, Lelievre Vincent, Waschek James A, Lazareff Jorge A, Freije William A, Liau Linda M, Gilbertson Richard J, Cloughesy Timothy F, Geschwind Daniel H, Nelson Stanley F, Mischel Paul S, Terskikh Alexey V, Kornblum Harley I
Maternal embryonic leucine zipper kinase is a key regulator of the
proliferation of malignant brain tumors, including brain tumor stem
cells
Journal of neuroscience research,
2008; 86(1):
48-60.
Seligson David B, Rajasekaran Sigrid A, Yu Hong, Liu Xueli, Eeva Mervi, Tze Sheila, Ball William, Horvath Steve, deKernion Jean B, Rajasekaran Ayyappan K
Na,K-adenosine triphosphatase alpha1-subunit predicts survival of
renal clear cell carcinoma
The Journal of urology,
2008; 179(1):
338-45.
Chen Yanqing, Zhu Jun, Lum Pek Yee, Yang Xia, Pinto Shirly, MacNeil Douglas J, Zhang Chunsheng, Lamb John, Edwards Stephen, Sieberts Solveig K, Leonardson Amy, Castellini Lawrence W, Wang Susanna, Champy Marie-France, Zhang Bin, Emilsson Valur, Doss Sudheer, Ghazalpour Anatole, Horvath Steve, Drake Thomas A, Lusis Aldons J, Schadt Eric E
Variations in DNA elucidate molecular networks that cause disease
Nature,
2008; 452(7186):
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Gong Ke Wei, Zhao Wei, Li Ning, Barajas Berenice, Kleinman Michael, Sioutas Constantinos, Horvath Steve, Lusis Aldons J, Nel Andre, Araujo Jesus A
Air-pollutant chemicals and oxidized lipids exhibit genome-wide
synergistic effects on endothelial cells
Genome biology,
2007; 8(7):
R149.
Abba MartÃn C, Sun Hongxia, Hawkins Kathleen A, Drake Jeffrey A, Hu Yuhui, Nunez Maria I, Gaddis Sally, Shi Tao, Horvath Steve, Sahin Aysegul, Aldaz C Marcelo
Breast cancer molecular signatures as determined by SAGE: correlation
with lymph node status
Molecular cancer research : MCR,
2007; 5(9):
881-90.
Seligson David B, Hongo Fumiya, Huerta-Yepez Sara, Mizutani Yoichi, Miki Tsuneharu, Yu Hong, Horvath Steve, Chia David, Goodglick Lee, Bonavida Benjamin
Expression of X-linked inhibitor of apoptosis protein is a strong
predictor of human prostate cancer recurrence
Clinical cancer research : an official journal of the American Association for Cancer Research,
2007; 13(20):
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Carlson Marc R J, Pope Whitney B, Horvath Steve, Braunstein Jerome G, Nghiemphu Phioanh, Tso Cho-Lea, Mellinghoff Ingo, Lai Albert, Liau Linda M, Mischel Paul S, Dong Jun, Nelson Stanley F, Cloughesy Timothy F
Relationship between survival and edema in malignant gliomas: role of
vascular endothelial growth factor and neuronal pentraxin 2
Clinical cancer research : an official journal of the American Association for Cancer Research,
2007; 13(9):
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Gargalovic Peter S, Imura Minori, Zhang Bin, Gharavi Nima M, Clark Michael J, Pagnon Joanne, Yang Wen-Pin, He Aiqing, Truong Amy, Patel Shilpa, Nelson Stanley F, Horvath Steve, Berliner Judith A, Kirchgessner Todd G, Lusis Aldons J
Identification of inflammatory gene modules based on variations of
human endothelial cell responses to oxidized lipids
Proceedings of the National Academy of Sciences of the United States of America,
2006; 103(34):
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Ghazalpour Anatole, Doss Sudheer, Zhang Bin, Wang Susanna, Plaisier Christopher, Castellanos Ruth, Brozell Alec, Schadt Eric E, Drake Thomas A, Lusis Aldons J, Horvath Steve
Integrating genetic and network analysis to characterize genes related
to mouse weight
PLoS genetics,
2006; 2(8):
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Lam John S, Shvarts Oleg, Said Jonathan W, Pantuck Allan J, Seligson David B, Aldridge Michael E, Bui Matthew H T, Liu Xueli, Horvath Steve, Figlin Robert A, Belldegrun Arie S
Clinicopathologic and molecular correlations of necrosis in the
primary tumor of patients with renal cell carcinoma
Cancer,
2005; 103(12):
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Seligson David, Horvath Steve, Huerta-Yepez Sara, Hanna Stephanie, Garban Hermes, Roberts Alice, Shi Tao, Liu Xueli, Chia David, Goodglick Lee, Bonavida Benjamin
Expression of transcription factor Yin Yang 1 in prostate cancer
International journal of oncology,
2005; 27(1):
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Ouyang Yan, Salstrom Jennifer, Diaz-Perez Silvia, Nahas Shareef, Matsuno Youko, Dawson David, Teitell Michael A, Horvath Steve, Riggs Arthur D, Gatti Richard A, Marahrens York
Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X
chromosome
Biochemical and biophysical research communications,
2005; 337(3):
875-80.
Mellinghoff Ingo K, Wang Maria Y, Vivanco Igor, Haas-Kogan Daphne A, Zhu Shaojun, Dia Ederlyn Q, Lu Kan V, Yoshimoto Koji, Huang Julie H Y, Chute Dennis J, Riggs Bridget L, Horvath Steve, Liau Linda M, Cavenee Webster K, Rao P Nagesh, Beroukhim Rameen, Peck Timothy C, Lee Jeffrey C, Sellers William R, Stokoe David, Prados Michael, Cloughesy Timothy F, Sawyers Charles L, Mischel Paul S
Molecular determinants of the response of glioblastomas to EGFR kinase
inhibitors
The New England journal of medicine,
2005; 353(19):
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Kim Hyung L, Seligson David, Liu Xueli, Janzen Nicolette, Bui Matthew H T, Yu Hong, Shi Tao, Belldegrun Arie S, Horvath Steve, Figlin Robert A
Using tumor markers to predict the survival of patients with
metastatic renal cell carcinoma
The Journal of urology,
2005; 173(5):
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Thomas George V, Horvath Steve, Smith Bradley L, Crosby Katherine, Lebel Lori A, Schrage Matthew, Said Jonathan, De Kernion Jean, Reiter Robert E, Sawyers Charles L
Antibody-based profiling of the phosphoinositide 3-kinase pathway in
clinical prostate cancer
Clinical cancer research : an official journal of the American Association for Cancer Research,
2004; 10(24):
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Flechner Stuart M, Kurian Sunil M, Head Steven R, Sharp Starlette M, Whisenant Thomas C, Zhang Jie, Chismar Jeffrey D, Horvath Steve, Mondala Tony, Gilmartin Timothy, Cook Daniel J, Kay Steven A, Walker John R, Salomon Daniel R
Kidney transplant rejection and tissue injury by gene profiling of
biopsies and peripheral blood lymphocytes
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons,
2004; 4(9):
1475-89.
Bui Matthew H T, Visapaa Harri, Seligson David, Kim Hyung, Han Ken-Ryu, Huang Yunda, Horvath Steve, Stanbridge Eric J, Palotie Aarno, Figlin Robert A, Belldegrun Arie S
Prognostic value of carbonic anhydrase IX and KI67 as predictors of
survival for renal clear cell carcinoma
The Journal of urology,
2004; 171(6 Pt 1):
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Kim Hyung L, Seligson David, Liu Xueli, Janzen Nicolette, Bui Matthew H T, Yu Hong, Shi Tao, Figlin Robert A, Horvath Steve, Belldegrun Arie S
Using protein expressions to predict survival in clear cell renal
carcinoma
Clinical cancer research : an official journal of the American Association for Cancer Research,
2004; 10(16):
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Espineda Cromwell, Seligson David B, James Ball William, Rao JianYu, Palotie Aarno, Horvath Steve, Huang Yunda, Shi Tao, Rajasekaran Ayyappan K
Analysis of the Na,K-ATPase alpha- and beta-subunit expression
profiles of bladder cancer using tissue microarrays
Cancer,
2003; 97(8):
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Choe Gheeyoung, Horvath Steve, Cloughesy Timothy F, Crosby Katherine, Seligson David, Palotie Aarno, Inge Landon, Smith Bradley L, Sawyers Charles L, Mischel Paul S
Analysis of the phosphatidylinositol 3'-kinase signaling pathway in
glioblastoma patients in vivo
Cancer research,
2003; 63(11):
2742-6.
Bui Matthew H T, Seligson David, Han Ken-ryu, Pantuck Allan J, Dorey Frederick J, Huang Yunda, Horvath Steve, Leibovich Bradley C, Chopra Shefali, Liao Shu-Yuan, Stanbridge Eric, Lerman Michael I, Palotie Aarno, Figlin Robert A, Belldegrun Arie S
Carbonic anhydrase IX is an independent predictor of survival in
advanced renal clear cell carcinoma: implications for prognosis and
therapy
Clinical cancer research : an official journal of the American Association for Cancer Research,
2003; 9(2):
802-11.
Visapää Harri, Bui Matthew, Huang Yunda, Seligson David, Tsai Henry, Pantuck Allan, Figlin Robert, Rao Jian Y u, Belldegrun Arie, Horvath Steve, Palotie Aarno
Correlation of Ki-67 and gelsolin expression to clinical outcome in
renal clear cell carcinoma
Urology,
2003; 61(4):
845-50.
Mischel Paul S, Shai Ruty, Shi Tao, Horvath Steve, Lu Kan V, Choe Gheeyoung, Seligson David, Kremen Thomas J, Palotie Aarno, Liau Linda M, Cloughesy Timothy F, Nelson Stanley F
Identification of molecular subtypes of glioblastoma by gene
expression profiling
Oncogene,
2003; 22(15):
2361-73.
Freedland Stephen J, Seligson David B, Liu Alvin Y, Pantuck Allan J, Paik Sun H, Horvath Steve, Wieder Jeffrey A, Zisman Amnon, Nguyen David, Tso Cho-Lea, Palotie Aarno V, Belldegrun Arie S
Loss of CD10 (neutral endopeptidase) is a frequent and early event in
human prostate cancer
The Prostate,
2003; 55(1):
71-80.
Haug Karsten, Warnstedt Maike, Alekov Alexi K, Sander Thomas, RamÃrez Alfredo, Poser Barbara, Maljevic Snezana, Hebeisen Simon, Kubisch Christian, Rebstock Johannes, Horvath Steve, Hallmann Kerstin, Dullinger Joern S, Rau Birgit, Haverkamp Fritz, Beyenburg Stefan, Schulz Herbert, Janz Dieter, Giese Bernd, Müller-Newen Gerhard, Propping Peter, Elger Christian E, Fahlke Christoph, Lerche Holger, Heils Armin
Mutations in CLCN2 encoding a voltage-gated chloride channel are
associated with idiopathic generalized epilepsies
Nature genetics,
2003; 33(4):
527-32.
Ide Hisamitsu, Seligson David B, Memarzadeh Sanaz, Xin Li, Horvath Steve, Dubey Purnima, Flick Maryann B, Kacinski Barry M, Palotie Aarno, Witte Owen N
Expression of colony-stimulating factor 1 receptor during prostate
development and prostate cancer progression
Proceedings of the National Academy of Sciences of the United States of America,
2002; 99(22):
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