Robert D Damoiseaux

Title(s)Adjunct Professor, Molecular and Medical Pharmacology
SchoolMedicine
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    Collapse Research 
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    Validation of an in vitro model of progressive fibrosis that mimics Idiopathic Pulmonary Fibrosis
    NIH U01HL153000Feb 15, 2021 - Jan 31, 2025
    Role: Co-Principal Investigator
    Development of a High-Throughput Screen for Pre-therapeutic Discovery in Idiopathic Pulmonary Fibrosis
    NIH R01GM114259Mar 1, 2015 - Feb 28, 2019
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. FLECS technology for high-throughput screening of hypercontractile cellular phenotypes in fibrosis: A function-first approach to anti-fibrotic drug discovery. SLAS Discov. 2023 Dec 28. Wang Y, Cortes E, Huang R, Wan J, Zhao J, Hinz B, Damoiseaux R, Pushkarsky I. PMID: 38158044.
      View in: PubMed   Mentions:    Fields:    
    2. MEK Inhibition Sensitizes Pancreatic Cancer to STING Agonism by Tumor Cell-intrinsic Amplification of Type I IFN Signaling. Clin Cancer Res. 2023 08 15; 29(16):3130-3141. Ghukasyan R, Liang K, Chau K, Li L, Chan C, Abt ER, Le T, Park JY, Wu N, Premji A, Damoiseaux R, Luu T, Labora A, Rashid K, Link JM, Radu CG, Donahue TR. PMID: 37195712; PMCID: PMC10865884.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    3. Adaptation of the Tumor Antigen Presentation Machinery to Ionizing Radiation. J Immunol. 2023 08 15; 211(4):693-705. Lee MH, Ratanachan D, Wang Z, Hack J, Adbulrahman L, Shamlin NP, Kalayjian M, Nesseler JP, Ganapathy E, Nguyen C, Ratikan JA, Cacalano NA, Austin D, Damoiseaux R, DiPardo BJ, Graham DS, Kalbasi A, Sayre JW, McBride WH, Schaue D. PMID: 37395687; PMCID: PMC10435044.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Comparative Analysis of Molecular Pathogenic Mechanisms and Antiviral Development Targeting Old and New World Hantaviruses. bioRxiv. 2023 Aug 05. Jeyachandran AV, Irudayam JI, Dubey S, Chakravarty N, Konda B, Shah A, Su B, Wang C, Cui Q, Williams KJ, Srikanth S, Shi Y, Deb A, Damoiseaux R, Stripp BR, Ramaiah A, Arumugaswami V. PMID: 37577539; PMCID: PMC10418258.
      View in: PubMed   Mentions:
    5. NSC95397 is a Novel HIV Latency Reversing Agent. bioRxiv. 2023 May 25. Nichols Doyle R, Yang V, Damoiseaux R, Fregoso OI. PMID: 37293110; PMCID: PMC10245985.
      View in: PubMed   Mentions:
    6. Osteopontin as a Biomarker in Chronic Kidney Disease. Biomedicines. 2023 May 04; 11(5). Sinha SK, Mellody M, Carpio MB, Damoiseaux R, Nicholas SB. PMID: 37239027; PMCID: PMC10216241.
      View in: PubMed   Mentions: 3  
    7. Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils. Nat Commun. 2023 04 25; 14(1):2379. Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. PMID: 37185252; PMCID: PMC10127185.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    8. Quantitative In Vivo Imaging of the Androgen Receptor Axis Reveals Degree of Prostate Cancer Radiotherapy Response. Mol Cancer Res. 2023 04 01; 21(4):307-315. Storey CM, Altai M, Bicak M, Veach DR, Lückerath K, Adrian G, McDevitt MR, Kalidindi T, Park JE, Herrmann K, Abou D, Zedan W, Peekhaus N, Klein RJ, Damoiseaux R, Larson SM, Lilja H, Thorek D, Ulmert D. PMID: 36608299; PMCID: PMC10355285.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    9. Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3. Sci Rep. 2023 01 25; 13(1):1442. Ghezzi C, Chen BY, Damoiseaux R, Clark PM. PMID: 36697489; PMCID: PMC9876922.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    10. Early Reduction of Glucose Consumption Is a Biomarker of Kinase Inhibitor Efficacy Which Can Be Reversed with GLUT1 Overexpression in Lung Cancer Cells. Mol Imaging Biol. 2023 06; 25(3):541-553. Ghezzi C, Perez S, Ryan K, Wong A, Chen BY, Damoiseaux R, Clark PM. PMID: 36284040; PMCID: PMC10732700.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    11. A quantitative high-throughput screen identifies compounds that lower expression of the SCA2-and ALS-associated gene ATXN2. J Biol Chem. 2022 08; 298(8):102228. Scoles DR, Gandelman M, Paul S, Dexheimer T, Dansithong W, Figueroa KP, Pflieger LT, Redlin S, Kales SC, Sun H, Maloney D, Damoiseaux R, Henderson MJ, Simeonov A, Jadhav A, Pulst SM. PMID: 35787375; PMCID: PMC9356275.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    12. Hydrogel Arrays Enable Increased Throughput for Screening Effects of Matrix Components and Therapeutics in 3D Tumor Models. J Vis Exp. 2022 06 16; (184). Liang J, Sohrabi A, Epperson M, Rad LM, Tamura K, Sathialingam M, Skandakumar T, Lue P, Huang J, Popoli J, Yackly A, Bick M, Wang ZZ, Chen CC, Varuzhanyan G, Damoiseaux R, Seidlits SK. PMID: 35781280; PMCID: PMC9969841.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Best practices for reporting throughput in biomedical research. Nat Methods. 2022 06; 19(6):633-634. Herbig M, Isozaki A, Di Carlo D, Guck J, Nitta N, Damoiseaux R, Kamikawaji S, Suyama E, Shintaku H, Wu AR, Nikaido I, Goda K. PMID: 35508736.
      View in: PubMed   Mentions: 2     Fields:    
    14. Simplified, High-throughput Analysis of Single-cell Contractility using Micropatterned Elastomers. J Vis Exp. 2022 04 08; (182). Hairapetian L, Cortes E, Zhao J, Wang Y, Huang R, Damoiseaux R, Pushkarsky I. PMID: 35467653.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    15. Suspendable Hydrogel Nanovials for Massively Parallel Single-Cell Functional Analysis and Sorting. ACS Nano. 2022 05 24; 16(5):7242-7257. de Rutte J, Dimatteo R, Archang MM, van Zee M, Koo D, Lee S, Sharrow AC, Krohl PJ, Mellody M, Zhu S, Eichenbaum JV, Kizerwetter M, Udani S, Ha K, Willson RC, Bertozzi AL, Spangler JB, Damoiseaux R, Di Carlo D. PMID: 35324146; PMCID: PMC9869715.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    16. Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair. J Clin Invest. 2022 01 18; 132(2). Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, Braddock DT, MacRae VE, Banerjee U, Chiou PY, Seldin M, Huang D, Teitell M, Gertsman I, Jung M, Bensinger SJ, Damoiseaux R, Faull K, Pellegrini M, Lusis AJ, Graeber TG, Radu CG, Deb A. PMID: 34813507; PMCID: PMC8759793.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    17. Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells. Cell Rep. 2022 01 11; 38(2):110236. Abt ER, Le TM, Dann AM, Capri JR, Poddar S, Lok V, Li L, Liang K, Creech AL, Rashid K, Kim W, Wu N, Cui J, Cho A, Lee HR, Rosser EW, Link JM, Czernin J, Wu TT, Damoiseaux R, Dawson DW, Donahue TR, Radu CG. PMID: 35021095; PMCID: PMC8893345.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    18. A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry. Viruses. 2021 10 20; 13(11). Luu AP, Yao Z, Ramachandran S, Azzopardi SA, Miles LA, Schneider WM, Hoffmann HH, Bozzacco L, Garcia G, Gong D, Damoiseaux R, Tang H, Morizono K, Rudin CM, Sun R, Arumugaswami V, Poirier JT, MacDonald MR, Rice CM, Li MMH. PMID: 34834920; PMCID: PMC8623001.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    19. Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition. Proc Natl Acad Sci U S A. 2021 10 19; 118(42). Liu X, Verma A, Garcia G, Ramage H, Lucas A, Myers RL, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS. PMID: 34593624; PMCID: PMC8594528.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    20. Targeting the Coronavirus Nucleocapsid Protein through GSK-3 Inhibition. medRxiv. 2021 Jul 21. Liu X, Verma A, Garcia G, Ramage H, Myers RL, Lucas A, Michaelson JJ, Coryell W, Kumar A, Charney AW, Kazanietz MG, Rader DJ, Ritchie MD, Berrettini WH, Schultz DC, Cherry S, Damoiseaux R, Arumugaswami V, Klein PS. PMID: 33655282; PMCID: PMC7924307.
      View in: PubMed   Mentions:
    21. Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples. Nat Biomed Eng. 2021 07; 5(7):657-665. Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Sina Booeshaghi A, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. PMID: 34211145; PMCID: PMC10810734.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    22. Classes of Drugs that Mitigate Radiation Syndromes. Front Pharmacol. 2021; 12:666776. Micewicz ED, Damoiseaux RD, Deng G, Gomez A, Iwamoto KS, Jung ME, Nguyen C, Norris AJ, Ratikan JA, Ruchala P, Sayre JW, Schaue D, Whitelegge JP, McBride WH. PMID: 34084139; PMCID: PMC8167044.
      View in: PubMed   Mentions: 3  
    23. DUSP7 regulates the activity of ERK2 to promote proper chromosome alignment during cell division. J Biol Chem. 2021 Jan-Jun; 296:100676. Guo X, Ramirez I, Garcia YA, Velasquez EF, Gholkar AA, Cohn W, Whitelegge JP, Tofig B, Damoiseaux R, Torres JZ. PMID: 33865857; PMCID: PMC8131738.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    24. SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition. Nat Commun. 2021 03 25; 12(1):1876. Mullen PJ, Garcia G, Purkayastha A, Matulionis N, Schmid EW, Momcilovic M, Sen C, Langerman J, Ramaiah A, Shackelford DB, Damoiseaux R, French SW, Plath K, Gomperts BN, Arumugaswami V, Christofk HR. PMID: 33767183; PMCID: PMC7994801.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    25. Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication. Cell Rep. 2021 04 06; 35(1):108940. Garcia G, Sharma A, Ramaiah A, Sen C, Purkayastha A, Kohn DB, Parcells MS, Beck S, Kim H, Bakowski MA, Kirkpatrick MG, Riva L, Wolff KC, Han B, Yuen C, Ulmert D, Purbey PK, Scumpia P, Beutler N, Rogers TF, Chatterjee AK, Gabriel G, Bartenschlager R, Gomperts B, Svendsen CN, Betz UAK, Damoiseaux RD, Arumugaswami V. PMID: 33784499; PMCID: PMC7969873.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    26. Inhibition of amyloid formation of the Nucleoprotein of SARS-CoV-2. bioRxiv. 2021 Mar 18. Tayeb-Fligelman E, Cheng X, Tai C, Bowler JT, Griner S, Sawaya MR, Seidler PM, Jiang YX, Lu J, Rosenberg GM, Salwinski L, Abskharon R, Zee CT, Hou K, Li Y, Boyer DR, Murray KA, Falcon G, Anderson DH, Cascio D, Saelices L, Damoiseaux R, Guo F, Eisenberg DS. PMID: 33688654; PMCID: PMC7941625.
      View in: PubMed   Mentions: 4  
    27. Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing. medRxiv. 2021 Mar 09. Bloom JS, Sathe L, Munugala C, Jones EM, Gasperini M, Lubock NB, Yarza F, Thompson EM, Kovary KM, Park J, Marquette D, Kay S, Lucas M, Love T, Booeshaghi AS, Brandenberg OF, Guo L, Boocock J, Hochman M, Simpkins SW, Lin I, LaPierre N, Hong D, Zhang Y, Oland G, Choe BJ, Chandrasekaran S, Hilt EE, Butte MJ, Damoiseaux R, Kravit C, Cooper AR, Yin Y, Pachter L, Garner OB, Flint J, Eskin E, Luo C, Kosuri S, Kruglyak L, Arboleda VA. PMID: 32909008; PMCID: PMC7480060.
      View in: PubMed   Mentions: 2  
    28. The myosin regulatory light chain Myl5 localizes to mitotic spindle poles and is required for proper cell division. Cytoskeleton (Hoboken). 2021 02; 78(2):23-35. Ramirez I, Gholkar AA, Velasquez EF, Guo X, Tofig B, Damoiseaux R, Torres JZ. PMID: 33641240; PMCID: PMC8722072.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    29. PSA-Targeted Alpha-, Beta-, and Positron-Emitting Immunotheranostics in Murine Prostate Cancer Models and Nonhuman Primates. Clin Cancer Res. 2021 04 01; 27(7):2050-2060. Veach DR, Storey CM, Lückerath K, Braun K, von Bodman C, Lamminmäki U, Kalidindi T, Strand SE, Strand J, Altai M, Damoiseaux R, Zanzonico P, Benabdallah N, Pankov D, Scher HI, Scardino P, Larson SM, Lilja H, McDevitt MR, Thorek DLJ, Ulmert D. PMID: 33441295; PMCID: PMC8278668.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    30. Targeting Corticotroph HDAC and PI3-Kinase in Cushing Disease. J Clin Endocrinol Metab. 2021 01 01; 106(1):e232-e246. Zhang D, Damoiseaux R, Babayan L, Rivera-Meza EK, Yang Y, Bergsneider M, Wang MB, Yong WH, Kelly K, Heaney AP. PMID: 33000123; PMCID: PMC8921634.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    31. Commercial immunoglobulin products contain cross-reactive but not neutralizing antibodies against SARS-CoV-2. J Allergy Clin Immunol. 2021 03; 147(3):876-877. Ahn TS, Han B, Krogstad P, Bun C, Kohn LA, Garcia-Lloret MI, Damoiseaux R, Butte MJ. PMID: 33358557; PMCID: PMC7833834.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington's disease patients. Sci Rep. 2020 11 20; 10(1):20295. Lee CYD, Wang N, Shen K, Stricos M, Langfelder P, Cheon KH, Cortés EP, Vinters HV, Vonsattel JP, Wexler NS, Damoiseaux R, Frydman J, Yang XW. PMID: 33219289; PMCID: PMC7679413.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    33. A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier. Cancer Res. 2021 02 01; 81(3):619-633. Hilfenhaus G, Mompeón A, Freshman J, Prajapati DP, Hernandez G, Freitas VM, Ma F, Langenbacher AD, Mirkov S, Song D, Cho BK, Goo YA, Pellegrini M, Chen JN, Damoiseaux R, Iruela-Arispe ML. PMID: 33218969; PMCID: PMC7916904.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    34. A Small-Molecule Approach to Restore a Slow-Oxidative Phenotype and Defective CaMKIIβ Signaling in Limb Girdle Muscular Dystrophy. Cell Rep Med. 2020 10 20; 1(7):100122. Liu J, Campagna J, John V, Damoiseaux R, Mokhonova E, Becerra D, Meng H, McNally EM, Pyle AD, Kramerova I, Spencer MJ. PMID: 33205074; PMCID: PMC7659555.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    35. Uncoupling interferon signaling and antigen presentation to overcome immunotherapy resistance due to JAK1 loss in melanoma. Sci Transl Med. 2020 10 14; 12(565). Kalbasi A, Tariveranmoshabad M, Hakimi K, Kremer S, Campbell KM, Funes JM, Vega-Crespo A, Parisi G, Champekar A, Nguyen C, Torrejon D, Shin D, Zaretsky JM, Damoiseaux RD, Speiser DE, Lopez-Casas PP, Quintero M, Ribas A. PMID: 33055240; PMCID: PMC8053376.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    36. High-throughput screening identifies modulators of sarcospan that stabilize muscle cells and exhibit activity in the mouse model of Duchenne muscular dystrophy. Skelet Muscle. 2020 09 18; 10(1):26. Shu C, Parfenova L, Mokhonova E, Collado JR, Damoiseaux R, Campagna J, John V, Crosbie RH. PMID: 32948250; PMCID: PMC7499884.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    37. Repurposing metformin, simvastatin and digoxin as a combination for targeted therapy for pancreatic ductal adenocarcinoma. Cancer Lett. 2020 10 28; 491:97-107. Liu SH, Yu J, Creeden JF, Sutton JM, Markowiak S, Sanchez R, Nemunaitis J, Kalinoski A, Zhang JT, Damoiseaux R, Erhardt P, Brunicardi FC. PMID: 32829010; PMCID: PMC8766172.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    38. Genetic signature of prostate cancer mouse models resistant to optimized hK2 targeted α-particle therapy. Proc Natl Acad Sci U S A. 2020 06 30; 117(26):15172-15181. Bicak M, Lückerath K, Kalidindi T, Phelps ME, Strand SE, Morris MJ, Radu CG, Damoiseaux R, Peltola MT, Peekhaus N, Ho A, Veach D, Malmborg Hager AC, Larson SM, Lilja H, McDevitt MR, Klein RJ, Ulmert D. PMID: 32532924; PMCID: PMC7334567.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    39. Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins. Nat Immunol. 2020 07; 21(7):746-755. Zhou QD, Chi X, Lee MS, Hsieh WY, Mkrtchyan JJ, Feng AC, He C, York AG, Bui VL, Kronenberger EB, Ferrari A, Xiao X, Daly AE, Tarling EJ, Damoiseaux R, Scumpia PO, Smale ST, Williams KJ, Tontonoz P, Bensinger SJ. PMID: 32514064; PMCID: PMC7778040.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    40. A Cell-based Screen in Actinomyces oris to Identify Sortase Inhibitors. Sci Rep. 2020 05 22; 10(1):8520. Gosschalk JE, Chang C, Sue CK, Siegel SD, Wu C, Kattke MD, Yi SW, Damoiseaux R, Jung ME, Ton-That H, Clubb RT. PMID: 32444661; PMCID: PMC7244523.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    41. The dopamine receptor antagonist trifluoperazine prevents phenotype conversion and improves survival in mouse models of glioblastoma. Proc Natl Acad Sci U S A. 2020 05 19; 117(20):11085-11096. Bhat K, Saki M, Vlashi E, Cheng F, Duhachek-Muggy S, Alli C, Yu G, Medina P, He L, Damoiseaux R, Pellegrini M, Zemke NR, Nghiemphu PL, Cloughesy TF, Liau LM, Kornblum HI, Pajonk F. PMID: 32358191; PMCID: PMC7245100.
      View in: PubMed   Mentions: 17     Fields:    Translation:Animals
    42. Mitigation of aflatoxin B1- and sodium arsenite-induced cytotoxicities in HUC-PC urinary bladder cells by curcumin and Khaya senegalensis. J Basic Clin Physiol Pharmacol. 2020 Apr 22; 31(4). Olugbami JO, Damoiseaux R, Odunola OA, Gimzewski JK. PMID: 32324162.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    43. Isoquinoline thiosemicarbazone displays potent anticancer activity with in vivo efficacy against aggressive leukemias. RSC Med Chem. 2020 Mar 01; 11(3):392-410. Sun DL, Poddar S, Pan RD, Rosser EW, Abt ER, Van Valkenburgh J, Le TM, Lok V, Hernandez SP, Song J, Li J, Turlik A, Chen X, Cheng CA, Chen W, Mona CE, Stuparu AD, Vergnes L, Reue K, Damoiseaux R, Zink JI, Czernin J, Donahue TR, Houk KN, Jung ME, Radu CG. PMID: 33479645; PMCID: PMC7593890.
      View in: PubMed   Mentions: 3  
    44. High-Throughput Drug Screening Identifies a Potent Wnt Inhibitor that Promotes Airway Basal Stem Cell Homeostasis. Cell Rep. 2020 02 18; 30(7):2055-2064.e5. Aros CJ, Paul MK, Pantoja CJ, Bisht B, Meneses LK, Vijayaraj P, Sandlin JM, France B, Tse JA, Chen MW, Shia DW, Rickabaugh TM, Damoiseaux R, Gomperts BN. PMID: 32075752; PMCID: PMC7050206.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    45. Development of a high-throughput screen to identify small molecule enhancers of sarcospan for the treatment of Duchenne muscular dystrophy. Skelet Muscle. 2019 12 12; 9(1):32. Shu C, Kaxon-Rupp AN, Collado JR, Damoiseaux R, Crosbie RH. PMID: 31831063; PMCID: PMC6907331.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    46. Modeling Progressive Fibrosis with Pluripotent Stem Cells Identifies an Anti-fibrotic Small Molecule. Cell Rep. 2019 12 10; 29(11):3488-3505.e9. Vijayaraj P, Minasyan A, Durra A, Karumbayaram S, Mehrabi M, Aros CJ, Ahadome SD, Shia DW, Chung K, Sandlin JM, Darmawan KF, Bhatt KV, Manze CC, Paul MK, Wilkinson DC, Yan W, Clark AT, Rickabaugh TM, Wallace WD, Graeber TG, Damoiseaux R, Gomperts BN. PMID: 31825831; PMCID: PMC6927560.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    47. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression. Cell Rep. 2019 Dec 10; 29(11):3766. Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A. PMID: 31825850.
      View in: PubMed   Mentions: 52     Fields:    
    48. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. Nat Commun. 2019 11 29; 10(1):5444. Ghezzi C, Wong A, Chen BY, Ribalet B, Damoiseaux R, Clark PM. PMID: 31784510; PMCID: PMC6884612.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    49. Metabolic Modifier Screen Reveals Secondary Targets of Protein Kinase Inhibitors within Nucleotide Metabolism. Cell Chem Biol. 2020 02 20; 27(2):197-205.e6. Abt ER, Rosser EW, Durst MA, Lok V, Poddar S, Le TM, Cho A, Kim W, Wei L, Song J, Capri JR, Xu S, Wu N, Slavik R, Jung ME, Damoiseaux R, Czernin J, Donahue TR, Lavie A, Radu CG. PMID: 31734178; PMCID: PMC7035983.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    50. An in situ high-throughput screen identifies inhibitors of intracellular Burkholderia pseudomallei with therapeutic efficacy. Proc Natl Acad Sci U S A. 2019 09 10; 116(37):18597-18606. Bulterys PL, Toesca IJ, Norris MH, Maloy JP, Fitz-Gibbon ST, France B, Toffig B, Morselli M, Somprasong N, Pellegrini M, Schweizer HP, Tuanyok A, Damoiseaux R, French CT, Miller JF. PMID: 31439817; PMCID: PMC6744847.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    51. PTPσ inhibitors promote hematopoietic stem cell regeneration. Nat Commun. 2019 08 14; 10(1):3667. Zhang Y, Roos M, Himburg H, Termini CM, Quarmyne M, Li M, Zhao L, Kan J, Fang T, Yan X, Pohl K, Diers E, Jin Gim H, Damoiseaux R, Whitelegge J, McBride W, Jung ME, Chute JP. PMID: 31413255; PMCID: PMC6694155.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    52. Leukemia Cell Cycle Chemical Profiling Identifies the G2-Phase Leukemia Specific Inhibitor Leusin-1. ACS Chem Biol. 2019 05 17; 14(5):994-1001. Xia X, Lo YC, Gholkar AA, Senese S, Ong JY, Velasquez EF, Damoiseaux R, Torres JZ. PMID: 31046221; PMCID: PMC6884739.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    53. Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor. Proc Natl Acad Sci U S A. 2019 05 14; 116(20):9959-9968. Mognol GP, González-Avalos E, Ghosh S, Spreafico R, Gudlur A, Rao A, Damoiseaux R, Hogan PG. PMID: 31019078; PMCID: PMC6525529.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    54. A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids. Commun Biol. 2019; 2:78. Phan N, Hong JJ, Tofig B, Mapua M, Elashoff D, Moatamed NA, Huang J, Memarzadeh S, Damoiseaux R, Soragni A. PMID: 30820473; PMCID: PMC6389967.
      View in: PubMed   Mentions: 101  Translation:Humans
    55. The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation. Radiat Res. 2019 04; 191(4):323-334. Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, Ganz T, Sayre JW, McBride WH, Schaue D. PMID: 30730284; PMCID: PMC6482953.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsPHPublic Health
    56. A scalable filtration method for high throughput screening based on cell deformability. Lab Chip. 2019 01 15; 19(2):343-357. Gill NK, Ly C, Nyberg KD, Lee L, Qi D, Tofig B, Reis-Sobreiro M, Dorigo O, Rao J, Wiedemeyer R, Karlan B, Lawrenson K, Freeman MR, Damoiseaux R, Rowat AC. PMID: 30566156.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    57. 1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer's patch-associated regenerating crypts in the small intestines after radiation injury. Radiother Oncol. 2019 03; 132:8-15. Bhat K, Duhachek-Muggy S, Ramanathan R, Saki M, Alli C, Medina P, Damoiseaux R, Whitelegge J, McBride WH, Schaue D, Vlashi E, Pajonk F. PMID: 30825974; PMCID: PMC6400303.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsPHPublic Health
    58. A Gelatin Microdroplet Platform for High-Throughput Sorting of Hyperproducing Single-Cell-Derived Microalgal Clones. Small. 2018 11; 14(44):e1803315. Li M, van Zee M, Riche CT, Tofig B, Gallaher SD, Merchant SS, Damoiseaux R, Goda K, Di Carlo D. PMID: 30369052.
      View in: PubMed   Mentions: 13     Fields:    
    59. Prevalence and patterns of higher-order drug interactions in Escherichia coli. NPJ Syst Biol Appl. 2018; 4:31. Tekin E, White C, Kang TM, Singh N, Cruz-Loya M, Damoiseaux R, Savage VM, Yeh PJ. PMID: 30181902; PMCID: PMC6119685.
      View in: PubMed   Mentions: 34     Fields:    
    60. Stressor interaction networks suggest antibiotic resistance co-opted from stress responses to temperature. ISME J. 2019 01; 13(1):12-23. Cruz-Loya M, Kang TM, Lozano NA, Watanabe R, Tekin E, Damoiseaux R, Savage VM, Yeh PJ. PMID: 30171253; PMCID: PMC6298959.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    61. Obesity increases airway smooth muscle responses to contractile agonists. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L673-L681. Orfanos S, Jude J, Deeney BT, Cao G, Rastogi D, van Zee M, Pushkarsky I, Munoz HE, Damoiseaux R, Di Carlo D, Panettieri RA. PMID: 30160518; PMCID: PMC6295505.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    62. A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. Cancer Metab. 2018; 6:7. Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. PMID: 29988332; PMCID: PMC6022704.
      View in: PubMed   Mentions: 12  
    63. A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma. Neuro Oncol. 2018 05 18; 20(6):764-775. Laks DR, Oses-Prieto JA, Alvarado AG, Nakashima J, Chand S, Azzam DB, Gholkar AA, Sperry J, Ludwig K, Condro MC, Nazarian S, Cardenas A, Shih MYS, Damoiseaux R, France B, Orozco N, Visnyei K, Crisman TJ, Gao F, Torres JZ, Coppola G, Burlingame AL, Kornblum HI. PMID: 29136244; PMCID: PMC5961175.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    64. Publisher Correction: Elastomeric sensor surfaces for high-throughput single-cell force cytometry. Nat Biomed Eng. 2018 Apr; 2(4):265. Pushkarsky I, Tseng P, Black D, France B, Warfe L, Koziol-White CJ, Jester WF, Trinh RK, Lin J, Scumpia PO, Morrison SL, Panettieri RA, Damoiseaux R, Di Carlo D. PMID: 31015734.
      View in: PubMed   Mentions: 1     Fields:    
    65. Elastomeric sensor surfaces for high-throughput single-cell force cytometry. Nat Biomed Eng. 2018 02; 2(2):124-137. Pushkarsky I, Tseng P, Black D, France B, Warfe L, Koziol-White CJ, Jester WF, Trinh RK, Lin J, Scumpia PO, Morrison SL, Panettieri RA, Damoiseaux R, Di Carlo D. PMID: 31015629; PMCID: PMC6619436.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    66. The Use of Somatic Hypermutation for the Affinity Maturation of Therapeutic Antibodies. Methods Mol Biol. 2018; 1827:479-489. Bowers PM, Boyle WJ, Damoiseaux R. PMID: 30196512; PMCID: PMC6497467.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    67. Making It All Work: Functional Genomics and Reporter Gene Assays. Methods Mol Biol. 2018; 1755:89-105. Welch G, Damoiseaux R, Miraglia L. PMID: 29671265.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    68. Reporter Gene Assays Using Transfectable Functional Genomics Libraries. Methods Mol Biol. 2018; 1755:107-120. Welch G, Damoiseaux R, Miraglia L. PMID: 29671266.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    69. High-Throughput Screening of a Luciferase Reporter of Gene Silencing on the Inactive X Chromosome. Methods Mol Biol. 2018; 1755:75-87. Keegan A, Plath K, Damoiseaux R. PMID: 29671264.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    70. Gα12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner. Br J Pharmacol. 2017 Dec; 174(23):4383-4395. Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA. PMID: 28921504; PMCID: PMC5715591.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    71. Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation. Oncotarget. 2017 Nov 28; 8(61):104007-104021. Senese S, Lo YC, Gholkar AA, Li CM, Huang Y, Mottahedeh J, Kornblum HI, Damoiseaux R, Torres JZ. PMID: 29262617; PMCID: PMC5732783.
      View in: PubMed   Mentions: 3     Fields:    
    72. Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. Cell Rep. 2017 Oct 10; 21(2):517-532. Watanabe M, Buth JE, Vishlaghi N, de la Torre-Ubieta L, Taxidis J, Khakh BS, Coppola G, Pearson CA, Yamauchi K, Gong D, Dai X, Damoiseaux R, Aliyari R, Liebscher S, Schenke-Layland K, Caneda C, Huang EJ, Zhang Y, Cheng G, Geschwind DH, Golshani P, Sun R, Novitch BG. PMID: 29020636; PMCID: PMC5637483.
      View in: PubMed   Mentions: 173     Fields:    Translation:HumansCells
    73. Exploiting Drug Addiction Mechanisms to Select against MAPKi-Resistant Melanoma. Cancer Discov. 2018 01; 8(1):74-93. Hong A, Moriceau G, Sun L, Lomeli S, Piva M, Damoiseaux R, Holmen SL, Sharpless NE, Hugo W, Lo RS. PMID: 28923912; PMCID: PMC6456057.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimals
    74. Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential. Sci Rep. 2017 09 12; 7(1):11261. Lo YC, Senese S, France B, Gholkar AA, Damoiseaux R, Torres JZ. PMID: 28900159; PMCID: PMC5595967.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    75. Recurrent Tumor Cell-Intrinsic and -Extrinsic Alterations during MAPKi-Induced Melanoma Regression and Early Adaptation. Cancer Discov. 2017 11; 7(11):1248-1265. Song C, Piva M, Sun L, Hong A, Moriceau G, Kong X, Zhang H, Lomeli S, Qian J, Yu CC, Damoiseaux R, Kelley MC, Dahlman KB, Scumpia PO, Sosman JA, Johnson DB, Ribas A, Hugo W, Lo RS. PMID: 28864476; PMCID: PMC6668729.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansAnimalsCells
    76. A comparative assessment of antiproliferative properties of resveratrol and ethanol leaf extract of Anogeissus leiocarpus (DC) Guill and Perr against HepG2 hepatocarcinoma cells. BMC Complement Altern Med. 2017 Aug 02; 17(1):381. Olugbami JO, Damoiseaux R, France B, Onibiyo EM, Gbadegesin MA, Sharma S, Gimzewski JK, Odunola OA. PMID: 28768515; PMCID: PMC5541659.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    77. 4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues. PLoS One. 2017; 12(7):e0181577. Micewicz ED, Kim K, Iwamoto KS, Ratikan JA, Cheng G, Boxx GM, Damoiseaux RD, Whitelegge JP, Ruchala P, Nguyen C, Purbey P, Loo J, Deng G, Jung ME, Sayre JW, Norris AJ, Schaue D, McBride WH. PMID: 28732024; PMCID: PMC5521796.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    78. Direct quantification of gamma H2AX by cell-based high throughput screening for evaluation of genotoxicity of pesticides in a human thyroid cell lines. Environ Mol Mutagen. 2017 08; 58(7):522-528. Hershman JM, France B, Hon K, Damoiseaux R. PMID: 28640454; PMCID: PMC6550478.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    79. Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression. Cell Rep. 2017 05 09; 19(6):1189-1201. Garcia-Diaz A, Shin DS, Moreno BH, Saco J, Escuin-Ordinas H, Rodriguez GA, Zaretsky JM, Sun L, Hugo W, Wang X, Parisi G, Saus CP, Torrejon DY, Graeber TG, Comin-Anduix B, Hu-Lieskovan S, Damoiseaux R, Lo RS, Ribas A. PMID: 28494868; PMCID: PMC6420824.
      View in: PubMed   Mentions: 807     Fields:    Translation:HumansCells
    80. When more is less: Emergent suppressive interactions in three-drug combinations. BMC Microbiol. 2017 05 06; 17(1):107. Beppler C, Tekin E, White C, Mao Z, Miller JH, Damoiseaux R, Savage VM, Yeh PJ. PMID: 28477626; PMCID: PMC5420147.
      View in: PubMed   Mentions: 11     Fields:    Translation:Cells
    81. Atomic force microscopy correlates antimetastatic potentials of HepG2 cell line with its redox/energy status: effects of curcumin and Khaya senegalensis. J Integr Med. 2017 05; 15(3):214-230. Olugbami JO, Damoiseaux R, France B, Gbadegesin MA, Stieg AZ, Sharma S, Odunola OA, Gimzewski JK. PMID: 28494852; PMCID: PMC6497468.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    82. Adaptation of a Genetic Screen Reveals an Inhibitor for Mitochondrial Protein Import Component Tim44. J Biol Chem. 2017 Mar 31; 292(13):5429-5442. Miyata N, Tang Z, Conti MA, Johnson ME, Douglas CJ, Hasson SA, Damoiseaux R, Chang CA, Koehler CM. PMID: 28167535; PMCID: PMC5392686.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    83. Engineering a Thermostable Keto Acid Decarboxylase Using Directed Evolution and Computationally Directed Protein Design. ACS Synth Biol. 2017 04 21; 6(4):610-618. Soh LMJ, Mak WS, Lin PP, Mi L, Chen FY, Damoiseaux R, Siegel JB, Liao JC. PMID: 28052191.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    84. Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner. Br J Pharmacol. 2016 09; 173(18):2726-38. Koziol-White CJ, Yoo EJ, Cao G, Zhang J, Papanikolaou E, Pushkarsky I, Andrews A, Himes BE, Damoiseaux RD, Liggett SB, Di Carlo D, Kurten RC, Panettieri RA. PMID: 27352269; PMCID: PMC4995285.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    85. 3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping. ACS Chem Biol. 2016 08 19; 11(8):2244-53. Lo YC, Senese S, Damoiseaux R, Torres JZ. PMID: 27285961; PMCID: PMC5511031.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    86. Copper status of exposed microorganisms influences susceptibility to metallic nanoparticles. Environ Toxicol Chem. 2016 May; 35(5):1148-58. Reyes VC, Spitzmiller MR, Hong-Hermesdorf A, Kropat J, Damoiseaux RD, Merchant SS, Mahendra S. PMID: 26387648; PMCID: PMC5439594.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    87. Characterization and evolution of an activator-independent methanol dehydrogenase from Cupriavidus necator N-1. Appl Microbiol Biotechnol. 2016 Jun; 100(11):4969-83. Wu TY, Chen CT, Liu JT, Bogorad IW, Damoiseaux R, Liao JC. PMID: 26846745.
      View in: PubMed   Mentions: 23     Fields:    Translation:Cells
    88. Discovery of Structurally Diverse Small-Molecule Compounds with Broad Antiviral Activity against Enteroviruses. Antimicrob Agents Chemother. 2015 Dec 28; 60(3):1615-26. Zuo J, Kye S, Quinn KK, Cooper P, Damoiseaux R, Krogstad P. PMID: 26711750; PMCID: PMC4775951.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    89. A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2'-dC upon inhibition of ribonucleotide reductase. Epigenetics Chromatin. 2015; 8:42. Minkovsky A, Sahakyan A, Bonora G, Damoiseaux R, Dimitrova E, Rubbi L, Pellegrini M, Radu CG, Plath K. PMID: 26468331; PMCID: PMC4604769.
      View in: PubMed   Mentions: 24     Fields:    
    90. Novel Arenavirus Entry Inhibitors Discovered by Using a Minigenome Rescue System for High-Throughput Drug Screening. J Virol. 2015 Aug; 89(16):8428-43. Rathbun JY, Droniou ME, Damoiseaux R, Haworth KG, Henley JE, Exline CM, Choe H, Cannon PM. PMID: 26041296; PMCID: PMC4524252.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    91. Glucocorticoids suppress renal cell carcinoma progression by enhancing Na,K-ATPase beta-1 subunit expression. PLoS One. 2015; 10(4):e0122442. Huynh TP, Barwe SP, Lee SJ, McSpadden R, Franco OE, Hayward SW, Damoiseaux R, Grubbs SS, Petrelli NJ, Rajasekaran AK. PMID: 25836370; PMCID: PMC4383530.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    92. Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens. PLoS Comput Biol. 2015 Mar; 11(3):e1004153. Lo YC, Senese S, Li CM, Hu Q, Huang Y, Damoiseaux R, Torres JZ. PMID: 25826798; PMCID: PMC4380459.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    93. Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1. PLoS One. 2015; 10(3):e0121833. Ting PY, Damoiseaux R, Titz B, Bradley KA, Graeber TG, Fernández-Vega V, Bannister TD, Chase P, Nair R, Scampavia L, Hodder P, Spicer TP, Colicelli J. PMID: 25811598; PMCID: PMC4374917.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    94. Comprehensive assessment of germline chemical toxicity using the nematode Caenorhabditis elegans. J Vis Exp. 2015 Feb 22; (96). Parodi DA, Damoiseaux R, Allard P. PMID: 25741987; PMCID: PMC4354655.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    95. Cytolethal distending toxins require components of the ER-associated degradation pathway for host cell entry. PLoS Pathog. 2014 Jul; 10(7):e1004295. Eshraghi A, Dixon SD, Tamilselvam B, Kim EJ, Gargi A, Kulik JC, Damoiseaux R, Blanke SR, Bradley KA. PMID: 25078082; PMCID: PMC4117610.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    96. UCLA's Molecular Screening Shared Resource: enhancing small molecule discovery with functional genomics and new technology. Comb Chem High Throughput Screen. 2014 May; 17(4):356-68. Damoiseaux R. PMID: 24661210.
      View in: PubMed   Mentions: 4     Fields:    
    97. Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation. J Immunol. 2014 Jan 01; 192(1):110-22. Kim KD, Srikanth S, Tan YV, Yee MK, Jew M, Damoiseaux R, Jung ME, Shimizu S, An DS, Ribalet B, Waschek JA, Gwack Y. PMID: 24307733; PMCID: PMC3874217.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    98. Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):E4904-12. Gillespie EJ, Ho CL, Balaji K, Clemens DL, Deng G, Wang YE, Elsaesser HJ, Tamilselvam B, Gargi A, Dixon SD, France B, Chamberlain BT, Blanke SR, Cheng G, de la Torre JC, Brooks DG, Jung ME, Colicelli J, Damoiseaux R, Bradley KA. PMID: 24191014; PMCID: PMC3864319.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    99. Genome-wide RNAi high-throughput screen identifies proteins necessary for the AHR-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol Sci. 2013 Nov; 136(1):107-19. Solaimani P, Damoiseaux R, Hankinson O. PMID: 23997114; PMCID: PMC3829574.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    100. Development of new deoxycytidine kinase inhibitors and noninvasive in vivo evaluation using positron emission tomography. J Med Chem. 2013 Sep 12; 56(17):6696-708. Murphy JM, Armijo AL, Nomme J, Lee CH, Smith QA, Li Z, Campbell DO, Liao HI, Nathanson DA, Austin WR, Lee JT, Darvish R, Wei L, Wang J, Su Y, Damoiseaux R, Sadeghi S, Phelps ME, Herschman HR, Czernin J, Alexandrova AN, Jung ME, Lavie A, Radu CG. PMID: 23947754; PMCID: PMC3789385.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    101. A new series of small molecular weight compounds induce read through of all three types of nonsense mutations in the ATM gene. Mol Ther. 2013 Sep; 21(9):1653-60. Du L, Jung ME, Damoiseaux R, Completo G, Fike F, Ku JM, Nahas S, Piao C, Hu H, Gatti RA. PMID: 23774824; PMCID: PMC3776636.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    102. A broadly applicable high-throughput screening strategy identifies new regulators of Dlg4 (Psd-95) alternative splicing. Genome Res. 2013 Jun; 23(6):998-1007. Zheng S, Damoiseaux R, Chen L, Black DL. PMID: 23636947; PMCID: PMC3668367.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    103. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15; 25(1):81-92. Dabir DV, Hasson SA, Setoguchi K, Johnson ME, Wongkongkathep P, Douglas CJ, Zimmerman J, Damoiseaux R, Teitell MA, Koehler CM. PMID: 23597483; PMCID: PMC3726224.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    104. High-throughput screening of small molecules identifies hepcidin antagonists. Mol Pharmacol. 2013 Mar; 83(3):681-90. Fung E, Sugianto P, Hsu J, Damoiseaux R, Ganz T, Nemeth E. PMID: 23292796; PMCID: PMC3583499.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    105. Dantrolene enhances antisense-mediated exon skipping in human and mouse models of Duchenne muscular dystrophy. Sci Transl Med. 2012 Dec 12; 4(164):164ra160. Kendall GC, Mokhonova EI, Moran M, Sejbuk NE, Wang DW, Silva O, Wang RT, Martinez L, Lu QL, Damoiseaux R, Spencer MJ, Nelson SF, Miceli MC. PMID: 23241744.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansAnimalsCells
    106. Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1. Small. 2013 May 27; 9(9-10):1776-85. Lin S, Zhao Y, Ji Z, Ear J, Chang CH, Zhang H, Low-Kam C, Yamada K, Meng H, Wang X, Liu R, Pokhrel S, Mädler L, Damoiseaux R, Xia T, Godwin HA, Lin S, Nel AE. PMID: 23180726; PMCID: PMC4034474.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    107. Genome-wide assessment in Escherichia coli reveals time-dependent nanotoxicity paradigms. ACS Nano. 2012 Nov 27; 6(11):9402-15. Reyes VC, Li M, Hoek EM, Mahendra S, Damoiseaux R. PMID: 23039911.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    108. Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO(2)) nanoparticles. Arch Toxicol. 2013 Jun; 87(6):1075-86. Xiong S, George S, Yu H, Damoiseaux R, France B, Ng KW, Loo JS. PMID: 22983807; PMCID: PMC5657381.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    109. Size of TiO(2) nanoparticles influences their phototoxicity: an in vitro investigation. Arch Toxicol. 2013 Jan; 87(1):99-109. Xiong S, George S, Ji Z, Lin S, Yu H, Damoiseaux R, France B, Ng KW, Loo SC. PMID: 22885792; PMCID: PMC5889301.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    110. Inhibition of aminoacylase 3 protects rat brain cortex neuronal cells from the toxicity of 4-hydroxy-2-nonenal mercapturate and 4-hydroxy-2-nonenal. Toxicol Appl Pharmacol. 2012 Sep 15; 263(3):303-14. Tsirulnikov K, Abuladze N, Bragin A, Faull K, Cascio D, Damoiseaux R, Schibler MJ, Pushkin A. PMID: 22819785; PMCID: PMC5575769.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    111. Fluoxetine is a potent inhibitor of coxsackievirus replication. Antimicrob Agents Chemother. 2012 Sep; 56(9):4838-44. Zuo J, Quinn KK, Kye S, Cooper P, Damoiseaux R, Krogstad P. PMID: 22751539; PMCID: PMC3421851.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    112. Quantitative detection of PfHRP2 in saliva of malaria patients in the Philippines. Malar J. 2012 May 25; 11:175. Fung AO, Damoiseaux R, Grundeen S, Panes JL, Horton DH, Judy JW, Moore TB. PMID: 22631858; PMCID: PMC3422183.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    113. Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. ACS Nano. 2012 May 22; 6(5):4349-68. Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, Pokhrel S, Lin S, Wang X, Liao YP, Wang M, Li L, Rallo R, Damoiseaux R, Telesca D, Mädler L, Cohen Y, Zink JI, Nel AE. PMID: 22502734; PMCID: PMC4139054.
      View in: PubMed   Mentions: 204     Fields:    Translation:Animals
    114. Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials. PLoS One. 2012; 7(4):e35014. Liu R, Lin S, Rallo R, Zhao Y, Damoiseaux R, Xia T, Lin S, Nel A, Cohen Y. PMID: 22506062; PMCID: PMC3323610.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    115. Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells. Mol Cancer Ther. 2012 Jun; 11(6):1320-31. Tai S, Sun Y, Liu N, Ding B, Hsia E, Bhuta S, Thor RK, Damoiseaux R, Liang C, Huang J. PMID: 22491797; PMCID: PMC3374015.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    116. Genome-wide bacterial toxicity screening uncovers the mechanisms of toxicity of a cationic polystyrene nanomaterial. Environ Sci Technol. 2012 Feb 21; 46(4):2398-405. Ivask A, Suarez E, Patel T, Boren D, Ji Z, Holden P, Telesca D, Damoiseaux R, Bradley KA, Godwin H. PMID: 22148163.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    117. Synergistic bactericidal activity of Ag-TiO₂ nanoparticles in both light and dark conditions. Environ Sci Technol. 2011 Oct 15; 45(20):8989-95. Li M, Noriega-Trevino ME, Nino-Martinez N, Marambio-Jones C, Wang J, Damoiseaux R, Ruiz F, Hoek EM. PMID: 21866941.
      View in: PubMed   Mentions: 24     Fields:    
    118. Seeing the light: luminescent reporter gene assays. Comb Chem High Throughput Screen. 2011 Sep; 14(8):648-57. Miraglia LJ, King FJ, Damoiseaux R. PMID: 21564017.
      View in: PubMed   Mentions: 13     Fields:    
    119. High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles. ACS Nano. 2011 Sep 27; 5(9):7284-95. Lin S, Zhao Y, Xia T, Meng H, Ji Z, Liu R, George S, Xiong S, Wang X, Zhang H, Pokhrel S, Mädler L, Damoiseaux R, Lin S, Nel AE. PMID: 21851096; PMCID: PMC4136441.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    120. A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells. Mol Cancer Ther. 2011 Oct; 10(10):1818-28. Visnyei K, Onodera H, Damoiseaux R, Saigusa K, Petrosyan S, De Vries D, Ferrari D, Saxe J, Panosyan EH, Masterman-Smith M, Mottahedeh J, Bradley KA, Huang J, Sabatti C, Nakano I, Kornblum HI. PMID: 21859839; PMCID: PMC3191241.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    121. High throughput screening of small molecule libraries for modifiers of radiation responses. Int J Radiat Biol. 2011 Aug; 87(8):839-45. Kim K, Damoiseaux R, Norris AJ, Rivina L, Bradley K, Jung ME, Gatti RA, Schiestl RH, McBride WH. PMID: 21401317; PMCID: PMC3203687.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    122. Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells. ACS Nano. 2011 Apr 26; 5(4):2756-2769. Zhang H, Xia T, Meng H, Xue M, George S, Ji Z, Wang X, Liu R, Wang M, France B, Rallo R, Damoiseaux R, Cohen Y, Bradley KA, Zink JI, Nel AE. PMID: 21366263; PMCID: PMC3896548.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    123. Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials. ACS Nano. 2011 Mar 22; 5(3):1805-17. George S, Xia T, Rallo R, Zhao Y, Ji Z, Lin S, Wang X, Zhang H, France B, Schoenfeld D, Damoiseaux R, Liu R, Lin S, Bradley KA, Cohen Y, Nel AE. PMID: 21323332; PMCID: PMC3896549.
      View in: PubMed   Mentions: 76     Fields:    Translation:Animals
    124. No time to lose--high throughput screening to assess nanomaterial safety. Nanoscale. 2011 Apr; 3(4):1345-60. Damoiseaux R, George S, Li M, Pokhrel S, Ji Z, France B, Xia T, Suarez E, Rallo R, Mädler L, Cohen Y, Hoek EM, Nel A. PMID: 21301704; PMCID: PMC3980675.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    125. Self-organizing map analysis of toxicity-related cell signaling pathways for metal and metal oxide nanoparticles. Environ Sci Technol. 2011 Feb 15; 45(4):1695-702. Rallo R, France B, Liu R, Nair S, George S, Damoiseaux R, Giralt F, Nel A, Bradley K, Cohen Y. PMID: 21250674; PMCID: PMC4418424.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    126. Metabolic imaging allows early prediction of response to vandetanib. J Nucl Med. 2011 Feb; 52(2):231-40. Walter MA, Benz MR, Hildebrandt IJ, Laing RE, Hartung V, Damoiseaux RD, Bockisch A, Phelps ME, Czernin J, Weber WA. PMID: 21233183.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    127. Microfluidic image cytometry. Methods Mol Biol. 2011; 706:191-206. Kamei K, Sun J, Tseng HR, Damoiseaux R. PMID: 21104065.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    128. Stability, bioavailability, and bacterial toxicity of ZnO and iron-doped ZnO nanoparticles in aquatic media. Environ Sci Technol. 2011 Jan 15; 45(2):755-61. Li M, Pokhrel S, Jin X, Mädler L, Damoiseaux R, Hoek EM. PMID: 21133426.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    129. High-throughput screening of silver nanoparticle stability and bacterial inactivation in aquatic media: influence of specific ions. Environ Sci Technol. 2010 Oct 01; 44(19):7321-8. Jin X, Li M, Wang J, Marambio-Jones C, Peng F, Huang X, Damoiseaux R, Hoek EM. PMID: 20873875.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    130. High-content screening for biofilm assays. J Biomol Screen. 2010 Aug; 15(7):748-54. Peng F, Hoek EM, Damoiseaux R. PMID: 20639506.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    131. Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nat Biotechnol. 2010 Jul; 28(7):738-42. Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, Li C, Houk KN, Jung ME, Zheng N, Huang L, Deshaies RJ, Kaiser P, Huang J. PMID: 20581845; PMCID: PMC2902569.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    132. Substrate specificity of the TIM22 mitochondrial import pathway revealed with small molecule inhibitor of protein translocation. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9578-83. Hasson SA, Damoiseaux R, Glavin JD, Dabir DV, Walker SS, Koehler CM. PMID: 20457929; PMCID: PMC2906835.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    133. Integrated pathways for neutrophil recruitment and inflammation in leprosy. J Infect Dis. 2010 Feb 15; 201(4):558-69. Lee DJ, Li H, Ochoa MT, Tanaka M, Carbone RJ, Damoiseaux R, Burdick A, Sarno EN, Rea TH, Modlin RL. PMID: 20070238; PMCID: PMC2811231.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    134. A broad-spectrum antiviral targeting entry of enveloped viruses. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):3157-62. Wolf MC, Freiberg AN, Zhang T, Akyol-Ataman Z, Grock A, Hong PW, Li J, Watson NF, Fang AQ, Aguilar HC, Porotto M, Honko AN, Damoiseaux R, Miller JP, Woodson SE, Chantasirivisal S, Fontanes V, Negrete OA, Krogstad P, Dasgupta A, Moscona A, Hensley LE, Whelan SP, Faull KF, Holbrook MR, Jung ME, Lee B. PMID: 20133606; PMCID: PMC2840368.
      View in: PubMed   Mentions: 134     Fields:    Translation:Animals
    135. Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. ACS Nano. 2010 Jan 26; 4(1):15-29. George S, Pokhrel S, Xia T, Gilbert B, Ji Z, Schowalter M, Rosenauer A, Damoiseaux R, Bradley KA, Mädler L, Nel AE. PMID: 20043640; PMCID: PMC3900637.
      View in: PubMed   Mentions: 121     Fields:    Translation:AnimalsCells
    136. High-throughput screening identifies two classes of antibiotics as radioprotectors: tetracyclines and fluoroquinolones. Clin Cancer Res. 2009 Dec 01; 15(23):7238-45. Kim K, Pollard JM, Norris AJ, McDonald JT, Sun Y, Micewicz E, Pettijohn K, Damoiseaux R, Iwamoto KS, Sayre JW, Price BD, Gatti RA, McBride WH. PMID: 19920105; PMCID: PMC2787903.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    137. Nonaminoglycoside compounds induce readthrough of nonsense mutations. J Exp Med. 2009 Sep 28; 206(10):2285-97. Du L, Damoiseaux R, Nahas S, Gao K, Hu H, Pollard JM, Goldstine J, Jung ME, Henning SM, Bertoni C, Gatti RA. PMID: 19770270; PMCID: PMC2757881.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    138. Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family. Am J Physiol Gastrointest Liver Physiol. 2010 Jan; 298(1):G63-73. Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA, Yokosuka O, Pandol SJ, Gukovskaya AS. PMID: 19762431; PMCID: PMC2806098.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    139. Discovery and structure-activity relationship analysis of Staphylococcus aureus sortase A inhibitors. Bioorg Med Chem. 2009 Oct 15; 17(20):7174-85. Suree N, Yi SW, Thieu W, Marohn M, Damoiseaux R, Chan A, Jung ME, Clubb RT. PMID: 19781950; PMCID: PMC2888031.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    140. Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells. Stem Cells. 2009 Mar; 27(3):533-542. Damoiseaux R, Sherman SP, Alva JA, Peterson C, Pyle AD. PMID: 19074420; PMCID: PMC3962308.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansCells
    141. Ion channel and toxin measurement using a high throughput lipid membrane platform. Biosens Bioelectron. 2009 Feb 15; 24(6):1806-10. Poulos JL, Jeon TJ, Damoiseaux R, Gillespie EJ, Bradley KA, Schmidt JJ. PMID: 18849158.
      View in: PubMed   Mentions: 13     Fields:    
    142. Regulation of Kaposi's sarcoma-associated herpesvirus reactivation by dopamine receptor-mediated signaling pathways. J Acquir Immune Defic Syndr. 2008 Aug 15; 48(5):531-40. Lee S, Deng H, Yu F, Melega WP, Damoiseaux R, Bradley KA, Sun R. PMID: 18645521.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    143. A high-throughput screening strategy identifies cardiotonic steroids as alternative splicing modulators. Proc Natl Acad Sci U S A. 2008 Aug 12; 105(32):11218-23. Stoilov P, Lin CH, Damoiseaux R, Nikolic J, Black DL. PMID: 18678901; PMCID: PMC2516208.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansCells
    144. Amiodarone and bepridil inhibit anthrax toxin entry into host cells. Antimicrob Agents Chemother. 2007 Jul; 51(7):2403-11. Sanchez AM, Thomas D, Gillespie EJ, Damoiseaux R, Rogers J, Saxe JP, Huang J, Manchester M, Bradley KA. PMID: 17485504; PMCID: PMC1913235.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    145. The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression. Cell Metab. 2007 May; 5(5):357-70. Waki H, Park KW, Mitro N, Pei L, Damoiseaux R, Wilpitz DC, Reue K, Saez E, Tontonoz P. PMID: 17488638.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    146. Mycophenolic acid is a potent inhibitor of angiogenesis. Arterioscler Thromb Vasc Biol. 2006 Oct; 26(10):2414-6. Wu X, Zhong H, Song J, Damoiseaux R, Yang Z, Lin S. PMID: 16990565.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    147. Cell-based chemical genetic screen identifies damnacanthal as an inhibitor of HIV-1 Vpr induced cell death. Biochem Biophys Res Commun. 2006 Sep 29; 348(3):1101-6. Kamata M, Wu RP, An DS, Saxe JP, Damoiseaux R, Phelps ME, Huang J, Chen IS. PMID: 16904642; PMCID: PMC1761125.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
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