Publications:
A selected list of publications:
Clifford Bethan L, Sedgeman Leslie R, Williams Kevin J, Morand Pauline, Cheng Angela, Jarrett Kelsey E, Chan Alvin P, Brearley-Sholto Madelaine C, Wahlström Annika, Ashby Julianne W, Barshop William, Wohlschlegel James, Calkin Anna C, Liu Yingying, Thorell Anders, Meikle Peter J, Drew Brian G, Mack Julia J, Marschall Hanns-Ulrich, Tarling Elizabeth J, Edwards Peter A, de Aguiar Vallim Thomas Q
FXR activation protects against NAFLD via bile-acid-dependent
reductions in lipid absorption
Cell metabolism,
2021; 33(8):
1671-1684.e4.
von Scheidt Moritz, Zhao Yuqi, de Aguiar Vallim Thomas Q, Che Nam, Wierer Michael, Seldin Marcus M, Franzén Oscar, Kurt Zeyneb, Pang Shichao, Bongiovanni Dario, Yamamoto Masayuki, Edwards Peter A, Ruusalepp Arno, Kovacic Jason C, Mann Matthias, Björkegren Johan L M, Lusis Aldons J, Yang Xia, Schunkert Heribert
Transcription Factor MAFF (MAF Basic Leucine Zipper Transcription
Factor F) Regulates an Atherosclerosis Relevant Network Connecting
Inflammation and Cholesterol Metabolism
Circulation,
2021; 143(18):
1809-1823.
Cheng Joan, Cheng Angela, Clifford Bethan L, Wu Xiaohui, Hedin Ulf, Maegdefessel Lars, Pamir Nathalie, Sallam Tamer, Tarling Elizabeth J, de Aguiar Vallim Thomas Q
MicroRNA-144 Silencing Protects Against Atherosclerosis in Male, but
Not Female Mice
Arteriosclerosis, thrombosis, and vascular biology,
2020; 40(2):
412-425.
Parker Benjamin L, Calkin Anna C, Seldin Marcus M, Keating Michael F, Tarling Elizabeth J, Yang Pengyi, Moody Sarah C, Liu Yingying, Zerenturk Eser J, Needham Elise J, Miller Matthew L, Clifford Bethan L, Morand Pauline, Watt Matthew J, Meex Ruth C R, Peng Kang-Yu, Lee Richard, Jayawardana Kaushala, Pan Calvin, Mellett Natalie A, Weir Jacquelyn M, Lazarus Ross, Lusis Aldons J, Meikle Peter J, James David E, de Aguiar Vallim Thomas Q, Drew Brian G
An integrative systems genetic analysis of mammalian lipid metabolism
Nature,
2019; 567(7747):
187-193.
Sullivan William J, Mullen Peter J, Schmid Ernst W, Flores Aimee, Momcilovic Milica, Sharpley Mark S, Jelinek David, Whiteley Andrew E, Maxwell Matthew B, Wilde Blake R, Banerjee Utpal, Coller Hilary A, Shackelford David B, Braas Daniel, Ayer Donald E, de Aguiar Vallim Thomas Q, Lowry William E, Christofk Heather R
Extracellular Matrix Remodeling Regulates Glucose Metabolism through
TXNIP Destabilization
Cell,
2018; 175(1):
117-132.e21.
Mack Julia J, Mosqueiro Thiago S, Archer Brian J, Jones William M, Sunshine Hannah, Faas Guido C, Briot Anais, Aragón Raquel L, Su Trent, Romay Milagros C, McDonald Austin I, Kuo Cheng-Hsiang, Lizama Carlos O, Lane Timothy F, Zovein Ann C, Fang Yun, Tarling Elizabeth J, de Aguiar Vallim Thomas Q, Navab Mohamad, Fogelman Alan M, Bouchard Louis S, Iruela-Arispe M Luisa
NOTCH1 is a mechanosensor in adult arteries
Nature communications,
2017; 8(1):
1620.
Sallam Tamer, Jones Marius C, Gilliland Thomas, Zhang Li, Wu Xiaohui, Eskin Ascia, Sandhu Jaspreet, Casero David, Vallim Thomas Q de Aguiar, Hong Cynthia, Katz Melanie, Lee Richard, Whitelegge Julian, Tontonoz Peter
Feedback modulation of cholesterol metabolism by the lipid-responsive
non-coding RNA LeXis
Nature,
2016; 534(7605):
124-8.
Wang Bo, Rong Xin, Duerr Mark A, Hermanson Daniel J, Hedde Per Niklas, Wong Jinny S, Vallim Thomas Q de Aguiar, Cravatt Benjamin F, Gratton Enrico, Ford David A, Tontonoz Peter
Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid
Uptake and Survival on a High-Fat Diet
Cell metabolism,
2016; 23(3):
492-504.
de Aguiar Vallim Thomas Q, Tarling Elizabeth J, Ahn Hannah, Hagey Lee R, Romanoski Casey E, Lee Richard G, Graham Mark J, Motohashi Hozumi, Yamamoto Masayuki, Edwards Peter A
MAFG is a transcriptional repressor of bile acid synthesis and
metabolism
Cell metabolism,
2015; 21(2):
298-310.
Bennett Brian J, de Aguiar Vallim Thomas Q, Wang Zeneng, Shih Diana M, Meng Yonghong, Gregory Jill, Allayee Hooman, Lee Richard, Graham Mark, Crooke Rosanne, Edwards Peter A, Hazen Stanley L, Lusis Aldons J
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis,
exhibits complex genetic and dietary regulation
Cell metabolism,
2013; 17(1):
49-60.