Marlin Touma, M.D.

A Short Biography:

Marlin Touma is an Asoociate Professor-In-Residence in the David Geffen School of Medicine, Department of Pediatrics and the Director of UCLA Congenital Heart Defects Research Program.  She joined the pediatric faculty in 2011 after completing her fellowship program in Neonatal-Perinatal Medicine at Boston Children’s Hospital/Harvard University. Dr. Touma received her medical education from Damascus University and obtained her PhD in Molecular, Cell & Integrative Physiology as an UCLA-STAR fellow in 2015. Dr. Touma is the founder and principal invistigator of the Neonatal/Congenital Heart Laboratory and BioCore for Congenital Heart Defects Research at UCLA. She is the recipient of several prestigious awards including an Outstanding Research Award from the American Academy of Pediatrics, Career Development Awards from the NIH/Child Health Research Center and American Heart Association, and the Manton Center for Orphan Disease Gene Discovery Award. As an early career investigator, Dr. Touma was awarded the David Geffen School of Medicine Research Innovation Award, and the High Priority “Bridge Fund” and an R01 from NIH/NHLBI. Dr. Touma is an awarded finalist of the 2021 Mid-Career Investigator (MCI) Research Scholarship Award from the International Society for Heart Research (ISHR)-North America Section (NAS). Dr. Touma's clinical practice is located in the Neonatal Intensive Care Unit, Mattel Children's Hospital at UCLA. She provide prenatal consultation services and perinatal care for affected families and newborn infants with prematurity complications and congenital heart defects.

Work Titles
UCLA Associate Professor In-Residence, Pediatric Neonatology

Contact Information:

Email Address:


A selected list of publications:

Zhao Yan, Wang Lee-Kai, Eskin Ascia, Kang Xuedong, Fajardo Viviana M, Mehta Zubin, Pineles Stacy, Schmidt Ryan J, Nagiel Aaron, Satou Gary, Garg Meena, Federman Myke, Reardon Leigh C, Lee Steven L, Biniwale Reshma, Grody Wayne W, Halnon Nancy, Khanlou Negar, Quintero-Rivera Fabiola, Alejos Juan C, Nakano Atsushi, Fishbein Gregory A, Van Arsdell Glen S, Nelson Stanley F, Touma Marlin   Recessive ciliopathy mutations in primary endocardial fibroelastosis: a rare neonatal cardiomyopathy in a case of Alstrom syndrome Journal of molecular medicine (Berlin, Germany), 2021; 99(11): 1623-1638.
Yokota Tomohiro, Li Jin, Huang Jijun, Xiong Zhaojun, Zhang Qing, Chan Tracey, Ding Yichen, Rau Christoph, Sung Kevin, Ren Shuxun, Kulkarni Rajan, Hsiai Tzung, Xiao Xinshu, Touma Marlin, Minamisawa Susumu, Wang Yibin   p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart The Journal of clinical investigation, 2020; 130(10): 5287-5301.
Touma Marlin   COVID-19: molecular diagnostics overview Journal of molecular medicine (Berlin, Germany), 2020; 98(7): 947-954.
Spyropoulos Fotios, Vitali Sally H, Touma Marlin, Rose Chase D, Petty Carter R, Levy Philip, Kourembanas Stella, Christou Helen   Echocardiographic markers of pulmonary hemodynamics and right ventricular hypertrophy in rat models of pulmonary hypertension Pulmonary circulation, 2020; 10(2): 2045894020910976.
Zhao Yan, Kang Xuedong, Barsegian Alexander, He Jian, Guzman Alejandra, Lau Ryan P, Biniwale Reshma, Wadhra Madhuri, Reemtsen Brian, Garg Meena, Halnon Nancy, Quintero-Rivera Fabiola, Grody Wayne W, Grody Wayne W, Van Arsdell Glen, Nelson Stanley F, Touma Marlin   Gene-environment regulation of chamber-specific maturation during hypoxemic perinatal circulatory transition Journal of molecular medicine (Berlin, Germany), 2020; 98(7): 1009-1020.
Kang Xuedong, Zhao Yan, Van Arsdell Glen, Nelson Stanley F, Touma Marlin   Ppp1r1b-lncRNA inhibits PRC2 at myogenic regulatory genes to promote cardiac and skeletal muscle development in mouse and human RNA (New York, N.Y.), 2020; 26(4): 481-491.
Zhao Yan, Kang Xuedong, Gao Fuying, Guzman Alejandra, Lau Ryan P, Biniwale Reshma, Wadehra Madhuri, Reemtsen Brian, Garg Meena, Halnon Nancy, Quintero-Rivera Fabiola, Van Arsdell Glen, Coppola Giovanni, Nelson Stanley F, Touma Marlin, Touma Marlin   Gene-environment regulatory circuits of right ventricular pathology in tetralogy of fallot Journal of molecular medicine (Berlin, Germany), 2019; 97(12): 1711-1722.
Touma Marlin   Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System Journal of visualized experiments : JoVE, 2018; 97(135): 1711-1722.
Touma Marlin, Reemtsen Brian, Halnon Nancy, Alejos Juan, Finn J Paul, Nelson Stanley F, Wang Yibin   A Path to Implement Precision Child Health Cardiovascular Medicine Frontiers in cardiovascular medicine, 2017; 4(17): 36.
Touma Marlin, Kang Xuedong, Gao Fuying, Zhao Yan, Cass Ashley A, Biniwale Reshma, Xiao Xinshu, Eghbali Mansuoreh, Coppola Giovanni, Reemtsen Brian, Wang Yibin   Wnt11 regulates cardiac chamber development and disease during perinatal maturation JCI insight, 2017; 2(17): 1711-1722.
Touma Marlin, Kang Xuedong, Zhao Yan, Cass Ashley A, Gao Fuying, Biniwale Reshma, Coppola Giovanni, Xiao Xinshu, Reemtsen Brian, Wang Yibin   Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery Circulation. Cardiovascular genetics, 2016; 9(5): 395-407.
Ganguly Amit, Touma Marlin, Thamotharan Shanthie, De Vivo Darryl C, Devaskar Sherin U   Maternal Calorie Restriction Causing Uteroplacental Insufficiency Differentially Affects Mammalian Placental Glucose and Leucine Transport Molecular Mechanisms Endocrinology, 2016; 157(10): 4041-4054.
Lluri Gentian, Huang Vincent, Touma Marlin, Liu Xiaoqian, Harmon Andrew W, Nakano Atsushi   Hematopoietic progenitors are required for proper development of coronary vasculature Journal of molecular and cellular cardiology, 2015; 86(10): 199-207.
Briot Anaïs, Jaroszewicz Artur, Warren Carmen M, Lu Jing, Touma Marlin, Rudat Carsten, Hofmann Jennifer J, Airik Rannar, Weinmaster Gerry, Lyons Karen, Wang Yibin, Kispert Andreas, Pellegrini Matteo, Iruela-Arispe M Luisa   Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells Developmental cell, 2014; 31(6): 707-21.
Xiao Xinshu Grace, Touma Marlin, Wang Yibin   Decoding the noncoding transcripts in human heart failure Circulation, 2014; 129(9): 958-60.
Nakashima Yasuhiro, Yanez Diana A, Touma Marlin, Nakano Haruko, Jaroszewicz Artur, Jordan Maria C, Pellegrini Matteo, Roos Kenneth P, Nakano Atsushi   Nkx2-5 suppresses the proliferation of atrial myocytes and conduction system Circulation research, 2014; 114(7): 1103-13.
Touma Marlin, Joshi Mugdha, Connolly Meghan C, Grant P Ellen, Hansen Anne R, Khwaja Omar, Berry Gerard T, Kinney Hannah C, Poduri Annapurna, Agrawal Pankaj B   Whole genome sequencing identifies SCN2A mutation in monozygotic twins with Ohtahara syndrome and unique neuropathologic findings Epilepsia, 2013; 54(5): e81-5.
Christou Helen, Reslan Ossama M, Mam Virak, Tanbe Alain F, Vitali Sally H, Touma Marlin, Arons Elena, Mitsialis S Alex, Kourembanas Stella, Khalil Raouf A   Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension American journal of physiology. Lung cellular and molecular physiology, 2012; 302(9): L875-90.

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