Kim-Lien Nguyen, M.D.

A Short Biography:

    Dr. Nguyen is a practicing non-invasive cardiologist and an Associate Professor of Medicine with secondary appointments in Radiology and Biomedical Physics. She received her MD from UCLA, did her internal medicine residency at Johns Hopkins, and completed a general cardiology fellowship at UCLA.  She served as a research fellow in the advanced cardiovascular imaging section at the National Institutes of Health and returned to UCLA as faculty.

    As an early career investigator, Dr. Nguyen's research focuses on the development, translation, and application of cardiovascular imaging techniques. She co-directs a cardiovascular imaging research lab. Her grant-funded work focuses on development of iron oxide enhanced MRI techniques in ischemic, vascular, and congenital heart disease. She collaborates with data scientists on the use of imaging data for advancement of precision medicine. Her work also explores methods to integrate wireless technology with traditional models of healthcare delivery. Her scientific work has been published in leading peer-reviewed journals and is funded by grants from the National Institutes of Health, the American Heart Association, and the Veterans Health Administration.

    As a Vietnam War refugee, Dr. Nguyen has a passion for helping our nation’s veterans who have sacrificed so much in service to our country.  Dr. Nguyen founded the cardiac MRI program at the VA Greater Los Angeles Healthcare System, which has served as a model for university/VA partnerships at other institutions. She collaborates with VA stakeholders and industry partners to facilitate veterans' access to state-of-the art cardiac imaging technology and cardiovascular clinical trials. As the founder and former director of the telecardiology clinic at VA Greater Los Angeles, Dr. Nguyen continues to promote the integration of telemedicine with traditional models of healthcare delivery to improve veterans' access to cardiovascular care.

     Dr. Nguyen has worked on public policy issues from the time she was a medical student when she obtained state grant funding to launch the first initiative to address minority health disparities in the School of Medicine at UCLA.  She continues to engage the public on issues relating to healthcare delivery and medical education. Her writing has been published in the general media including Forbes, USA Today, Medical Economics, STAT News, and The Hill. She also serves the broader community through involvement on several advisory boards and mentorship of women in STEM-related disciplines.


Work Titles
CTSI Member, CTSI
UCLA Associate Professor In-Residence, Medicine Faculty, Physics & Biology in Medicine GPB Home Area
Education:
Degrees:
M.D., David Geffen School of Medicine at UCLA

Contact Information:

Office Phone Number:

310-268-3839

Office Address:

11301 Wilshire Blvd
Building 500
Los Angeles, CA 90073

300 Medical Plaza, B119
Los Angeles, CA 90095


Publications:

A selected list of publications:

Colbert Caroline M, Le Anna H, Shao Jiaxin, Currier Jesse W, Ajijola Olujimi A, Hu Peng, Nguyen Kim-Lien   Ferumoxytol-enhanced magnetic resonance T1 reactivity for depiction of myocardial hypoperfusion NMR in biomedicine, 2021; e4518.
Nguyen Kim-Lien, Ghosh Reena M, Griffin Lindsay M, Yoshida Takegawa, Bedayat Arash, Rigsby Cynthia K, Fogel Mark A, Whitehead Kevin K, Hu Peng, Finn J Paul   Four-dimensional Multiphase Steady-State MRI with Ferumoxytol Enhancement: Early Multicenter Feasibility in Pediatric Congenital Heart Disease Radiology, 2021; 203696.
Lu Yi, Huang Jenny, Neverova Natalia V, Nguyen Kim-Lien   USPIOs as targeted contrast agents in cardiovascular magnetic resonance imaging Current cardiovascular imaging reports, 2021; 14(2): e4518.
Nguyen Kim-Lien, Hu Peng, Finn J Paul   Cardiac Magnetic Resonance Quantification of Structure-Function Relationships in Heart Failure Heart failure clinics, 2021; 17(1): 9-24.
Colbert Caroline M, Thomas Michael A, Yan Ran, Radjenovic Aleksandra, Finn J Paul, Hu Peng, Nguyen Kim-Lien   Estimation of fractional myocardial blood volume and water exchange using ferumoxytol-enhanced magnetic resonance imaging Journal of magnetic resonance imaging : JMRI, 2020; .
Ghodrati Vahid, Bydder Mark, Ali Fadil, Gao Chang, Prosper Ashley, Nguyen Kim-Lien, Hu Peng   Retrospective respiratory motion correction in cardiac cine MRI reconstruction using adversarial autoencoder and unsupervised learning NMR in biomedicine, 2020; 17(1): e4433.
Kathuria-Prakash Nikhita, Honda Henry, Nguyen Kim-Lien   Improving preclinical medical student teaching skills through patient education Postgraduate medical journal, 2020; 17(1): e4433.
Neilan Tomas G, Nguyen Kim-Lien, Zaha Vlad G, Chew Kara W, Morrison Leavitt, Ntusi Ntobeko A B, Toribio Mabel, Awadalla Magid, Drobni Zsofia D, Nelson Michael D, Burdo Tricia H, Van Schalkwyk Marije, Sax Paul E, Skiest Daniel J, Tashima Karen, Landovitz Raphael J, Daar Eric, Wurcel Alysse G, Robbins Gregory K, Bolan Robert K, Fitch Kathleen V, Currier Judith S, Bloomfield Gerald S, Desvigne-Nickens Patrice, Douglas Pamela S, Hoffmann Udo, Grinspoon Steven K, Ribaudo Heather, Dawson Rodney, Goetz Matthew Bidwell, Jain Mamta K, Warner Alberta, Szczepaniak Lidia S, Zanni Markella V   Myocardial Steatosis Among Antiretroviral Therapy-Treated People With Human Immunodeficiency Virus Participating in the REPRIEVE Trial The Journal of infectious diseases, 2020; 222(Supplement_1): S63-S69.
Thomas Michael A, Hazany Saman, Ellingson Benjamin M, Hu Peng, Nguyen Kim-Lien   Pathophysiology, Classification, and MRI Parallels in Microvascular Disease of the Heart and Brain Microcirculation (New York, N.Y. : 1994), 2020; 222(Supplement_1): S63-S69.
Ho David R, Luery Sarah E, Ghosh Reena M, Maehara Cleo K, Silvestro Elizabeth, Whitehead Kevin K, Sze Raymond W, Hsu William, Nguyen Kim-Lien   Cardiovascular 3-D Printing: Value-Added Assessment Using Time-Driven Activity-Based Costing Journal of the American College of Radiology : JACR, 2020; 222(Supplement_1): S63-S69.
Colbert Caroline M, Shao Jiaxin, Hollowed John J, Currier Jesse W, Ajijola Olujimi A, Fishbein Gregory A, Duarte-Vogel Sandra M, Dharmakumar Rohan, Hu Peng, Nguyen Kim-Lien   3D-Printed Coronary Implants Are Effective for Percutaneous Creation of Swine Models with Focal Coronary Stenosis Journal of cardiovascular translational research, 2020; .
Shao Jiaxin, Ghodrati Vahid, Nguyen Kim-Lien, Hu Peng   Fast and accurate calculation of myocardial T Magnetic resonance in medicine, 2020; .
Abiri Parinaz, Yousefi Alireza, Abiri Arash, Gudapati Varun, Ding Yichen, Nguyen Kim-Lien, Abiri Ahmad, Markovic Dejan, Tai Yu-Chong, Hsiai Tzung K   A Multi-Dimensional Analysis of a Novel Approach for Wireless Stimulation IEEE transactions on bio-medical engineering, 2020; .
So-Armah Kaku A, Lim Joseph K, Re Vincent Lo, Tate Janet P, Chang Chung-Chou H, Butt Adeel A, Gibert Cynthia L, Rimland David, Marconi Vincent C, Goetz Matthew Bidwell, Ramachandran Vasan, Brittain Evan, Long Michelle, Nguyen Kim-Lien, Rodriguez-Barradas Maria C, Budoff Matthew J, Tindle Hilary A, Samet Jeffrey H, Justice Amy C, Freiberg Matthew S, Freiberg Matthew S   FIB-4 stage of liver fibrosis is associated with incident heart failure with preserved, but not reduced, ejection fraction among people with and without HIV or hepatitis C Progress in cardiovascular diseases, 2020; .
Hollowed John J, Colbert Caroline M, Currier Jesse W, Nguyen Kim-Lien   Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease Journal of visualized experiments : JoVE, 2020; (156): .
Sharma Shilpa, Hanudel Mark R, Ix Joachim H, Salusky Isidro B, Ganz Tomas, Nguyen Kim-Lien   Elevated Fibroblast Growth Factor 23 Levels Are Associated With Greater Diastolic Dysfunction in ESRD Kidney international reports, 2019; 4(12): 1748-1751.
Yoshida Takegawa, Nguyen Kim-Lien, Shahrouki Puja, Quinones-Baldrich William J, Lawrence Peter F, Finn J Paul   Intermodality feature fusion combining unenhanced computed tomography and ferumoxytol-enhanced magnetic resonance angiography for patient-specific vascular mapping in renal impairment Journal of vascular surgery, 2019; .
Nguyen Kim-Lien, Yoshida Takegawa, Kathuria-Prakash Nikhita, Zaki Islam H, Varallyay Csanad G, Semple Scott I, Saouaf Rola, Rigsby Cynthia K, Stoumpos Sokratis, Whitehead Kevin K, Griffin Lindsay M, Saloner David, Hope Michael D, Prince Martin R, Fogel Mark A, Schiebler Mark L, Roditi Giles H, Radjenovic Aleksandra, Newby David E, Neuwelt Edward A, Bashir Mustafa R, Hu Peng, Finn J Paul   Multicenter Safety and Practice for Off-Label Diagnostic Use of Ferumoxytol in MRI Radiology, 2019; 190477.
Ghodrati Vahid, Shao Jiaxin, Bydder Mark, Zhou Ziwu, Yin Wotao, Nguyen Kim-Lien, Yang Yingli, Hu Peng   MR image reconstruction using deep learning: evaluation of network structure and loss functions Quantitative imaging in medicine and surgery, 2019; 9(9): 1516-1527.
Shao Jiaxin, Zhou Ziwu, Nguyen Kim-Lien, Finn J Paul, Hu Peng   Accurate, precise, simultaneous myocardial T1 and T2 mapping using a radial sequence with inversion recovery and T2 preparation NMR in biomedicine, 2019; e4165.
Nguyen Kim-Lien, Shao Jiaxin, Ghodrati Vahid K, Ajijola Olujimi A, Dharmakumar Rohan, Finn J Paul, Hu Peng   Ferumoxytol-Enhanced CMR for Vasodilator Stress Testing: A Feasibility Study JACC. Cardiovascular imaging, 2019; 21(1): 17.
Shahrouki Puja, Moriarty John M, Khan Sarah N, Bista Biraj, Kee Stephen T, DeRubertis Brian G, Yoshida Takegawa, Nguyen Kim-Lien, Finn J Paul   High resolution, 3-dimensional Ferumoxytol-enhanced cardiovascular magnetic resonance venography in central venous occlusion Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2019; 21(1): 17.
Bauer Brenton S, Nguyen-Phan Ai Len, Ong Michael K, Ziaeian Boback, Nguyen Kim-Lien   Cardiology electronic consultations: Efficient and safe but consultant satisfaction is equivocal Journal of telemedicine and telecare, 2019; 21(1): 1357633X19828130.
Zhou Ziwu, Han Fei, Yoshida Takegawa, Nguyen Kim-Lien, Finn John Paul, Hu Peng   Improved 4D cardiac functional assessment for pediatric patients using motion-weighted image reconstruction Magma (New York, N.Y.), 2018; 31(6): 747-756.
Patel Nisha R, Chyu Christopher K, Satou Gary M, Halnon Nancy J, Nguyen Kim-Lien   Left atrial function in children and young adult cancer survivors treated with anthracyclines Echocardiography (Mount Kisco, N.Y.), 2018; 35(10): 1649-1656.
Tuzovic Mirela, Wu Pei-Tzu, Kianmahd Samuel, Nguyen Kim-Lien   Natural history of myocardial deformation in children, adolescents, and young adults exposed to anthracyclines: Systematic review and meta-analysis Echocardiography (Mount Kisco, N.Y.), 2018; 35(7): 922-934.
Wu Pei T, Segovia David E, Lee Cathy C, Nguyen Kim-Lien   Consistency of Continuous Ambulatory Interstitial Glucose Monitoring Sensors Biosensors, 2018; 8(2): 922-934.
Nguyen Kim-Lien, Moriarty John M, Plotnik Adam N, Aksoy Olcay, Yoshida Takegawa, Shemin Richard J, Suh William M, Finn J Paul   Ferumoxytol-enhanced MR Angiography for Vascular Access Mapping before Transcatheter Aortic Valve Replacement in Patients with Renal Impairment: A Step Toward Patient-specific Care Radiology, 2018; 286(1): 326-337.
Moazeni Shayan, Cadeiras Martin, Yang Eric H, Deng Mario C, Nguyen Kim-Lien   Anthracycline induced cardiotoxicity: biomarkers and "Omics" technology in the era of patient specific care Clinical and translational medicine, 2017; 6(1): 17.
Nguyen Kim-Lien, Park Eun-Ah, Yoshida Takegawa, Hu Peng, Finn J Paul   Ferumoxytol enhanced black-blood cardiovascular magnetic resonance imaging Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2017; 19(1): 106.
Shao Jiaxin, Liu Dapeng, Sung Kyunghyun, Nguyen Kim-Lien, Hu Peng   Accuracy, precision, and reproducibility of myocardial T1 mapping: A comparison of four T1 estimation algorithms for modified look-locker inversion recovery (MOLLI) Magnetic resonance in medicine, 2017; 78(5): 1746-1756.
Finn J Paul, Nguyen Kim-Lien, Hu Peng   Ferumoxytol vs. Gadolinium agents for contrast-enhanced MRI: Thoughts on evolving indications, risks, and benefits Journal of magnetic resonance imaging : JMRI, 2017; 46(3): 919-923.
Han Fei, Zhou Ziwu, Han Eric, Gao Yu, Nguyen Kim-Lien, Finn J Paul, Hu Peng   Self-gated 4D multiphase, steady-state imaging with contrast enhancement (MUSIC) using rotating cartesian K-space (ROCK): Validation in children with congenital heart disease Magnetic resonance in medicine, 2017; 78(2): 472-483.
Abiri Parinaz, Abiri Ahmad, Packard René R Sevag, Ding Yichen, Yousefi Alireza, Ma Jianguo, Bersohn Malcolm, Nguyen Kim-Lien, Markovic Dejan, Moloudi Shervin, Hsiai Tzung K   Inductively powered wireless pacing via a miniature pacemaker and remote stimulation control system Scientific reports, 2017; 7(1): 6180.
Nguyen Kim-Lien, Han Fei, Zhou Ziwu, Brunengraber Daniel Z, Ayad Ihab, Levi Daniel S, Satou Gary M, Reemtsen Brian L, Hu Peng, Finn J Paul   4D MUSIC CMR: value-based imaging of neonates and infants with congenital heart disease Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2017; 19(1): 40.
Shao Jiaxin, Rashid Shams, Renella Pierangelo, Nguyen Kim-Lien, Hu Peng   Myocardial T1 mapping for patients with implanted cardiac devices using wideband inversion recovery spoiled gradient echo readout Magnetic resonance in medicine, 2017; 77(4): 1495-1504.
Demer Linda L, Tintut Yin, Nguyen Kim-Lien, Hsiai Tzung, Lee Jason T   Rigor and Reproducibility in Analysis of Vascular Calcification Circulation research, 2017; 120(8): 1240-1242.
Nguyen Kim-Lien, Yoshida Takegawa, Han Fei, Ayad Ihab, Reemtsen Brian L, Salusky Isidro B, Satou Gary M, Hu Peng, Finn J Paul   MRI with ferumoxytol: A single center experience of safety across the age spectrum Journal of magnetic resonance imaging : JMRI, 2017; 45(3): 804-812.
Chen Joseph J, Wu Pei-Tzu, Middlekauff Holly R, Nguyen Kim-Lien   Aerobic exercise in anthracycline-induced cardiotoxicity: a systematic review of current evidence and future directions American journal of physiology. Heart and circulatory physiology, 2017; 312(2): H213-H222.
Zhou Ziwu, Han Fei, Rapacchi Stanislas, Nguyen Kim-Lien, Brunengraber Daniel Z, Kim Grace-Hyun J, Finn J Paul, Hu Peng   Accelerated ferumoxytol-enhanced 4D multiphase, steady-state imaging with contrast enhancement (MUSIC) cardiovascular MRI: validation in pediatric congenital heart disease NMR in biomedicine, 2017; 30(1): H213-H222.
Nguyen Kim-Lien, Hu Peng, Ennis Daniel B, Shao Jiaxin, Pham Kimberly A, Chen Joseph J   Cardiac MRI: a Translational Imaging Tool for Characterizing Anthracycline-Induced Myocardial Remodeling Current oncology reports, 2016; 18(8): 48.
Han Fei, Zhou Ziwu, Rapacchi Stanislas, Nguyen Kim-Lien, Finn J Paul, Hu Peng   Segmented golden ratio radial reordering with variable temporal resolution for dynamic cardiac MRI Magnetic resonance in medicine, 2016; 76(1): 94-103.
Vasanawala Shreyas S, Nguyen Kim-Lien, Hope Michael D, Bridges Mellena D, Hope Thomas A, Reeder Scott B, Bashir Mustafa R   Safety and technique of ferumoxytol administration for MRI Magnetic resonance in medicine, 2016; 75(5): 2107-11.
Wickramasinghe Chanaka D, Nguyen Kim-Lien, Watson Karol E, Vorobiof Gabriel, Yang Eric H   Concepts in cardio-oncology: definitions, mechanisms, diagnosis and treatment strategies of cancer therapy-induced cardiotoxicity Future oncology (London, England), 2016; 12(6): 855-70.
Nguyen Kim-Lien, Tian Xin, Alam Shoaib, Mehari Alem, Leung Steve W, Seamon Catherine, Allen Darlene, Minniti Caterina P, Sachdev Vandana, Arai Andrew E, Kato Gregory J   Elevated transpulmonary gradient and cardiac magnetic resonance-derived right ventricular remodeling predict poor outcomes in sickle cell disease Haematologica, 2016; 101(2): e40-3.
Shao Jiaxin, Rapacchi Stanislas, Nguyen Kim-Lien, Hu Peng   Myocardial T1 mapping at 3.0 tesla using an inversion recovery spoiled gradient echo readout and bloch equation simulation with slice profile correction (BLESSPC) T1 estimation algorithm Journal of magnetic resonance imaging : JMRI, 2016; 43(2): 414-25.
Shao Jiaxin, Nguyen Kim-Lien, Natsuaki Yutaka, Spottiswoode Bruce, Hu Peng   Instantaneous signal loss simulation (InSiL): an improved algorithm for myocardial T₁ mapping using the MOLLI sequence Journal of magnetic resonance imaging : JMRI, 2015; 41(3): 721-9.
Nguyen Kim-Lien, Alrezk Rami, Mansourian Pejman G, Naeim Arash, Rettig Matthew B, Lee Cathy C   The Crossroads of Geriatric Cardiology and Cardio-Oncology Current geriatrics reports, 2015; 4(4): 327-337.
Nguyen Kim-Lien, Khan Sarah N, Moriarty John M, Mohajer Kiyarash, Renella Pierangelo, Satou Gary, Ayad Ihab, Patel Swati, Boechat M Ines, Finn J Paul   High-field MR imaging in pediatric congenital heart disease: initial results Pediatric radiology, 2015; 45(1): 42-54.
Nguyen Kim-Lien, Bandettini W Patricia, Shanbhag Sujata, Leung Steve W, Wilson Joel R, Arai Andrew E   Safety and tolerability of regadenoson CMR European heart journal cardiovascular Imaging, 2014; 15(7): 753-60.
Wagner Moritz, Nguyen Kim-Lien, Khan Sarah, Mirsadraee Saeed, Satou Gary M, Aboulhosn Jamil, Finn J Paul   Contrast-enhanced MR angiography of cavopulmonary connections in adult patients with congenital heart disease AJR. American journal of roentgenology, 2012; 199(5): W565-74.
Nguyen Kim-Lien, llano Manuel, Akari Hirofumi, Miyagi Eri, Poeschla Eric M, Strebel Klaus, Bour Stephan   Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression Virology, 2004; 319(2): 163-75.

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