Josephine Enciso, M.D.

A Short Biography:

Josephine Enciso, M.D., Associate Clinical Professor Pediatrics/Neonatology & Developmental Biology. Dr. Enciso received her MD at the University of Arizona College of Medicine in 1996 and completed her residency in Pediatrics in 1999 at Tufts University School of Medicine/New England Medical Center-Floating Hospital for Children. Dr. Enciso received her initial research training in the laboratory of Dr. Joseph Madri, Professor of Pathology, at Yale University School of Medicine from 1999-2003, at which time she had also completed subspecialty fellowship training in Neonatology/Perinatal Medicine. In November 2007, Dr. Enciso joined the Division of Neonatology at David Geffen School of Medicine at UCLA. In the Arispe Lab, Dr. Enciso is currently investigating the endothelial cell-specific role of progesterone receptor in inflammation.

Work Titles
UCLA Health Sciences Associate Clinical Professor, Pediatric Neonatology
M.D., University of Arizona School of Medicine, 1992 - 1996
1999 - 2003 Yale-New Haven Hospital/Yale University School of Medicine, Fellowship
1996 - 1999 Floating Hospital for Children, New England Medical Center/Tufts University School of Medicine, Residency
2003 American Board of Pediatrics, Medical Board Certification
1999 American Board of Pediatrics, Medical Board Certification

Contact Information:

Email Address:



Work Phone Number:

(310) 825-0867


Work Address:

10833 Le Conte Avenue, B2-375 MDCC
MC 175217
Los Angeles, CA 90095


A selected list of publications:

Goddard Lauren M, Murphy Thomas J, Org Tönis, Enciso Josephine M, Hashimoto-Partyka Minako K, Warren Carmen M, Domigan Courtney K, McDonald Austin I, He Huanhuan, Sanchez Lauren A, Allen Nancy C, Orsenigo Fabrizio, Chao Lily C, Dejana Elisabetta, Tontonoz Peter, Mikkola Hanna K A, Iruela-Arispe M Luisa   Progesterone receptor in the vascular endothelium triggers physiological uterine permeability preimplantation Cell, 2014; 156(3): 549-62.
Hofmann Jennifer J, Briot Anais, Enciso Josephine, Zovein Ann C, Ren Shuxun, Zhang Zhen W, Radtke Freddy, Simons Michael, Wang Yibin, Iruela-Arispe M Luisa   Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome Development (Cambridge, England), 2012; 139(23): 4449-60.
Enciso Josephine M, Konecny Christine M, Karpen Heidi E, Hirschi Karen K   Endothelial cell migration during murine yolk sac vascular remodeling occurs by means of a Rac1 and FAK activation pathway in vivo Developmental dynamics : an official publication of the American Association of Anatomists, 2010; 239(10): 2570-83.
Enciso JM, Hirschi KK.   Nutrient regulation of tumor and vascular endothelial cell proliferation, Curr Cancer Drug Targets, 2007; 7(5): 432-7.
Sinha Anuj, Fernandes Caraciolo J, Kim Jeffrey J, Fenrich Arnold L, Enciso Josephine   Atrial flutter following placement of an umbilical venous catheter Am J Perinatol, 2005; 22(5): 275-7.
Enciso Josephine M, Hirschi Karen K   Understanding abnormalities in vascular specification and remodeling Pediatrics, 2005; 116(1): 228-30.
Hallaq Haifa, Pinter Emese, Enciso Josephine, McGrath James, Zeiss Caroline, Brueckner Martina, Madri Joseph, Jacobs Harris C, Wilson Christine M, Vasavada Hemaxi, Jiang Xiaobing, Bogue Clifford W   A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels Development, 2004; 131(20): 5197-209.
Madri Joseph A, Enciso Josephine, Pinter Emese   Maternal diabetes: effects on embryonic vascular development--a vascular endothelial growth factor-A-mediated process Pediatr. Dev. Pathol, 2004; 6(4): 334-41.
Nath Anjali K, Enciso Josephine, Kuniyasu Misako, Hao Xiao-Ying, Madri Joseph A, Pinter Emese   Nitric oxide modulates murine yolk sac vasculogenesis and rescues glucose induced vasculopathy Development, 2004; 131(10): 2485-96.
Enciso Josephine M, Gratzinger Dita, Camenisch Todd D, Canosa Sandra, Pinter Emese, Madri Joseph A   Elevated glucose inhibits VEGF-A-mediated endocardial cushion formation: modulation by PECAM-1 and MMP-2 J. Cell Biol, 2003; 160(4): 605-15.

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