Gustavo Miranda-Carboni

A Short Biography:

Dr. Gustavo Miranda-Carboni's reasearch interests are on modeling human breast cancer using mouse models of the Wnt/beta-catenin signaling pathway. His translation model is for a subset of human breast cancers known as Triple-Negative which afflicts African-American women three times higher than other ethnic groups. This type of breast cancer is highly aggressive, lacks any known therapeutics and afflicts pre-menopausal women at ~33 percent of the time upon diagnosis.

Work Titles
UCLA Assistant Professor, Obstetrics and Gynecology Member, JCCC Signal Transduction and Therapeutics Program Area

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A selected list of publications:

Garcia Alejandro J, Tom Colton, Guemes Miriam, Polanco Gloria, Mayorga Maria E, Wend Korinna, Miranda-Carboni Gustavo A, Krum Susan A   ER? signaling regulates MMP3 expression to induce FasL cleavage and osteoclast apoptosis Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2013; 28(2): 283-90.
Wend Korinna, Wend Peter, Drew Brian G, Hevener Andrea L, Miranda-Carboni Gustavo A, Krum Susan A   ER? regulates lipid metabolism in bone through ATGL and perilipin Journal of cellular biochemistry, 2013; 28(2): .
Wend Peter, Runke Stephanie, Wend Korinna, Anchondo Brenda, Yesayan Maria, Jardon Meghan, Hardie Natalie, Loddenkemper Christoph, Ulasov Ilya, Lesniak Maciej S, Wolsky Rebecca, Bentolila Laurent A, Grant Stephen G, Elashoff David, Lehr Stephan, Latimer Jean J, Bose Shikha, Sattar Husain, Krum Susan A, Miranda-Carboni Gustavo A   WNT10B/?-catenin signalling induces HMGA2 and proliferation in metastatic triple-negative breast cancer EMBO molecular medicine, 2013; 28(2): .
Miranda-Carboni Gustavo A, Guemes Miriam, Bailey Shannon, Anaya Edgar, Corselli Mirko, Peault Bruno, Krum Susan A   GATA4 regulates estrogen receptor-alpha-mediated osteoblast transcription Molecular endocrinology (Baltimore, Md.), 2011; 25(7): 1126-36.

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