Isaac Yang, M.D.

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A Short Biography:

Isaac Yang M.D. is currently an Attending Neurosurgeon in the UCLA Department of Neurosurgery, an Associate Professor in the David Geffen School of Medicine, and a Principal Investigator in the UCLA Brain Tumor Laboratory. Originally from Lodi, California, Isaac’s interest in neurobiology started as an undergraduate as he received his bachelor’s degree with Phi Beta Kappa from the University of California Berkeley. His training followed with a medical degree from the University of California Los Angeles Geffen School of Medicine. Dr. Yang completed a neurological surgery residency at the University of California San Francisco, as well as an NRSA NIH funded F32 post doctoral brain tumor research fellowship. Dr. Yang’s clinical focus has been primarily on brain tumors both glioblastoma and skull base tumors. His research efforts have examined antigen expression and manipulation of the immune response to glioblastoma. He has previously been recognized with a UCSF Clinical and Translational Scientist Training Award and the CNS Dandy Clinical Research Fellowship. Dr. Yang has been the recipient of several distinguished regional and national awards including the UCSF Medical Center 2010 Exceptional Physician Award, the AANS Integra Brain Tumor Research Award, San Francisco Neurological Society Edwin Boldrey Award for Basic Science Research, American Academy of Neurological and Orthopedic Surgeons Research Award, Kaiser Award for Clinical Research, the national AANS Leksell Radiosurgery Award, and the Tumor Section Ronald L. Bittner Award on Brain Tumor Research. Dr. Yang has published over 90 publications in peer-reviewed journals and has authored over half a dozen book chapters. At UCLA, he is currently investigating the utilization of nanoparticles and nanotechnology for the application in brain tumor immunotherapy and vaccines. Dr. Isaac Yang is dedicated to improving the care and treatment of all patients with brain tumors. If interested please follow Dr. Yang on Facebook at Isaac Yang UCLA Neurosurgery or find his most recent book Service Minded Physician on Amazon.
Work Titles
CTSI Member, CTSI
UCLA Associate Professor, Neurosurgery Member, JCCC Signal Transduction and Therapeutics Program Area
Education:
Degrees:
M.D.
Certifications:
Certification Type:

Contact Information:

Email Address:

iyang@mednet.ucla.edu


Website:

profile website

Work Phone Number:

(310) 267-2621

Mailing Address:

Office
695 Charles E. Young Drive South, Gonda 3357
Gonda 3357
Los Angeles, CA 90095


Office Address:

300 Stein Plaza
Suite 420
Los Angeles, CA 90095


Detailed Biography:

Isaac Yang M.D. was born in Chicago Illinois to his South Korean parents who had recently emigrated to the United States. He grew up in Lodi, California, and completed his undergraduate education with Phi Beta Kappa from the UC Berkeley and received his medical degree from UCLA. After graduating from medical school with AOA honors, he completed his general surgical internship and neurosurgical residency at the UCSF Medical Center in San Francisco. During residency, he performed an NIH funded brain tumor fellowship at the UCSF Brain Tumor Research Center. Upon completion of residency with the UCSF Medical Center Exceptional Physician Award, he joined the UCLA Department of Neurosurgery and the UCLA Brain Tumor Center. Dr. Yang’s clinical focus has been primarily on brain tumors both glioblastoma and skull base tumors. His research efforts have examined antigen expression and manipulation of the immune response to glioblastoma. His efforts were recognized by the American Association of Neurological Surgeons and Congress of Neurological Surgeons Joint Section on Tumors and he was awarded the Tumor Young Investigator Award in 2012. Dr. Yang has been the recipient of several distinguished regional and national awards including the Exceptional Physician Award, the AANS Integra Brain Tumor Research Award, Boldrey Award for Basic Science Research, American Academy of Neurological and Orthopedic Surgeons Research Award, Kaiser Award for Clinical Research, the national AANS Leksell Radiosurgery Award, and the Tumor Section Ronald L. Bittner Award on Brain Tumor Research. In the Department of Neurosurgery at UCLA, he he leads a multidisciplinary effort in the treatment of brain tumors, contributes to the basic and clinical research program in the Department of Neurosurgery and is actively involved in resident physician (4 consecutive resident teaching awards) and medical student education (Director of Medical Student Education and Dean’s Excellence in Education Award). He has served as course faculty in multiple didactic/practical skull base workshops and is the Director of Medical Student Education at the UCLA Department of Neurosurgery. Dr. Isaac Yang is a nationally, recognized leader in neurosurgery and brain tumors, having served on the Executive Committee of the AANS/CNS Tumor Section since 2012, and serving on the editorial board of the Journal of Neuro Oncology and Surgical Neurology International. As of January 2014, he is serving as the co-editor of the Neurosurgical Clinics of North America. Dr. Yang has published over 90 publications in peer-reviewed journals and has authored over multiple book chapters and several textbooks, including the second edition of Service Minded Physician.

Publications:

A selected list of publications:

Yew Andrew, Trang Andy, Nagasawa Daniel T, Spasic Marko, Choy Winward, Garcia Heather M, Yang Isaac   Chromosomal alterations, prognostic factors, and targeted molecular therapies for malignant meningiomas Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2013; 20(1): 17-22.
Nagasawa Daniel T, Trang Andy, Choy Winward, Spasic Marko, Yew Andrew, Zarinkhou Golmah, Garcia Heather M, Yang Isaac   Genetic expression profiles of adult and pediatric ependymomas: molecular pathways, prognostic indicators, and therapeutic targets Clinical neurology and neurosurgery, 2013; 115(4): 388-99.
Sherman Jonathan H, Smith Zachary A, Cho Jin Mo, Lim Michael, Colen Chaim B, Kim Chae-Yong, Wang Vincent Yat, Zada Gabriel, Li Gordon, Yang Isaac   Neurosurgery concepts: Key perspectives on regulatory proteins, management of ossification of the posterior longitudinal ligament, and radiosurgery for intracranial lesions Surgical neurology international, 2013; 4(4): 35.
Nagasawa Daniel T, Choy Winward, Spasic Marko, Yew Andrew, Trang Andy, Garcia Heather M, Yang Isaac   An analysis of intracranial epidermoid tumors with malignant transformation: treatment and outcomes Clinical neurology and neurosurgery, 2012; 20(1): .
Choy Winward, Nagasawa Daniel T, Trang Andy, Thill Kimberly, Spasic Marko, Yang Isaac   CD133 as a marker for regulation and potential for targeted therapies in glioblastoma multiforme Neurosurgery clinics of North America, 2012; 23(3): 391-405.
Yang Isaac, Nagasawa Daniel T, Kim Won, Spasic Marko, Trang Andy, Lu Daniel C, Martin Neil A   Chromosomal anomalies and prognostic markers for intracranial and spinal ependymomas Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012; 19(6): 779-85.
Kim Won, Clelland Claire, Yang Isaac, Pouratian Nader   Comprehensive review of stereotactic radiosurgery for medically and surgically refractory pituitary adenomas Surgical neurology international, 2012; 3(Suppl 2): S79-89.
Smith Zachary A, Yang Isaac, Gorgulho Alessandra, Raphael Dan, De Salles Antonio A F, Khoo Larry T   Emerging techniques in the minimally invasive treatment and management of thoracic spine tumors Journal of neuro-oncology, 2012; 107(3): 443-55.
Yang Jian, Nagasawa Daniel T, Spasic Marko, Amolis Misha, Choy Winward, Garcia Heather M, Prins Robert M, Liau Linda M, Yang Isaac   Endogenous vaults and bioengineered vault nanoparticles for treatment of glioblastomas: implications for future targeted therapies Neurosurgery clinics of North America, 2012; 23(3): 451-8.
Fong Brendan M, Pezeshkian Patrick, Nagasawa Daniel T, De Salles Antonio, Gopen Quinton, Yang Isaac   Hearing preservation after LINAC radiosurgery and LINAC radiotherapy for vestibular schwannoma Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012; .
Oh Taemin, Nagasawa Daniel T, Fong Brendan M, Trang Andy, Gopen Quinton, Parsa Andrew T, Yang Isaac   Intraoperative neuromonitoring techniques in the surgical management of acoustic neuromas Neurosurgical focus, 2012; 33(3): E6.
Lawton Cort D, Nagasawa Daniel T, Yang Isaac, Fessler Richard G, Smith Zachary A   Leptomeningeal spinal metastases from glioblastoma multiforme: treatment and management of an uncommon manifestation of disease Journal of neurosurgery. Spine, 2012; 17(5): 438-48.
Yang Isaac, Han Seunggu J   Modern management of high grade glioma, part II Neurosurgery clinics of North America, 2012; 23(3): xiii-xiv.
Spasic Marko, Chow Frances, Tu Claire, Nagasawa Daniel T, Yang Isaac   Molecular characteristics and pathways of Avastin for the treatment of glioblastoma multiforme Neurosurgery clinics of North America, 2012; 23(3): 417-27.
Fong Brendan, Jin Richard, Wang Xiaoyan, Safaee Michael, Lisiero Dominique N, Yang Isaac, Li Gang, Liau Linda M, Prins Robert M   Monitoring of regulatory T cell frequencies and expression of CTLA-4 on T cells, before and after DC vaccination, can predict survival in GBM patients PloS one, 2012; 7(4): e32614.
Nagasawa Daniel T, Fong Christina, Yew Andrew, Spasic Marko, Garcia Heather M, Kruse Carol A, Yang Isaac   Passive immunotherapeutic strategies for the treatment of malignant gliomas Neurosurgery clinics of North America, 2012; 23(3): 481-95.
Lim Michael, Sherman Jonathan H, Wang Vincent Y, Smith Zachary A, Cho Jin Mo, Colen Chaim B, Kim Chae Yong, Zada Gabriel, Li Gordon, Yang Isaac   Perspectives on key articles in neurosurgery Surgical neurology international, 2012; 3(Suppl 2): 58.
Yang Isaac, Han Seunggu J   Preface. Modern management of high grade glioma, Part I Neurosurgery clinics of North America, 2012; 23(2): xiii.
Nagasawa Daniel T, Chow Frances, Yew Andrew, Kim Won, Cremer Nicole, Yang Isaac   Temozolomide and other potential agents for the treatment of glioblastoma multiforme Neurosurgery clinics of North America, 2012; 23(2): 307-22, ix.
Jian Brian J, Bloch Orin G, Yang Isaac, Han Seunggu J, Aranda Derrick, Parsa Andrew T   A comprehensive analysis of intracranial chordoma and survival: a systematic review British journal of neurosurgery, 2011; 25(4): 446-53.
Sughrue Michael E, Yang Isaac, Aranda Derick, Rutkowski Martin J, Fang Shanna, Cheung Steven W, Parsa Andrew T   Beyond audiofacial morbidity after vestibular schwannoma surgery Journal of neurosurgery, 2011; 114(2): 367-74.
Nagasawa Daniel, Yew Andrew, Safaee Michael, Fong Brendan, Gopen Quinton, Parsa Andrew T, Yang Isaac   Clinical characteristics and diagnostic imaging of epidermoid tumors Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011; 18(9): 1158-62.
Nagasawa Daniel T, Smith Zachary A, Cremer Nicole, Fong Christina, Lu Daniel C, Yang Isaac   Complications associated with the treatment for spinal ependymomas Neurosurgical focus, 2011; 31(4): E13.
Yew Andrew, Kim Won, Chang Sue, Yang Isaac   Delayed intracranial and bony metastasis of paraganglioma Surgical neurology international, 2011; 2(1): 62.
Yang Isaac, Chang Edward F, Han Seunggu J, Barry Jeffrey J, Fang Shanna, Tihan Tarik, Barbaro Nicholas M, Parsa Andrew T   Early surgical intervention in adult patients with ganglioglioma is associated with improved clinical seizure outcomes Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011; 18(1): 29-33.
Sughrue Michael E, Yang Isaac, Kane Ari J, Fang Shanna, Clark Aaron J, Aranda Derrick, Barani Igor J, Parsa Andrew T   Endocrinologic, neurologic, and visual morbidity after treatment for craniopharyngioma Journal of neuro-oncology, 2011; 101(3): 463-76.
Sughrue Michael E, Kaur Rajwant, Rutkowski Martin J, Kane Ari J, Kaur Gurvinder, Yang Isaac, Pitts Lawrence H, Parsa Andrew T   Extent of resection and the long-term durability of vestibular schwannoma surgery Journal of neurosurgery, 2011; 114(5): 1218-23.
Bloch Orin, Sughrue Michael E, Kaur Rajwant, Kane Ari J, Rutkowski Martin J, Kaur Gurvinder, Yang Isaac, Pitts Lawrence H, Parsa Andrew T   Factors associated with preservation of facial nerve function after surgical resection of vestibular schwannoma Journal of neuro-oncology, 2011; 102(2): 281-6.
See Alfred P, Pradilla Gustavo, Yang Isaac, Han Seunggu, Parsa Andrew T, Lim Michael   Heat shock protein-peptide complex in the treatment of glioblastoma Expert review of vaccines, 2011; 10(6): 721-31.
Yang Isaac, Han Seunggu J, Sughrue Michael E, Tihan Tarik, Parsa Andrew T   Immune cell infiltrate differences in pilocytic astrocytoma and glioblastoma: evidence of distinct immunological microenvironments that reflect tumor biology Journal of neurosurgery, 2011; 115(3): 505-11.
Jian Brian J, Sughrue Michael E, Kaur Rajwant, Rutkowski Martin J, Kane Ari J, Kaur Gurvinder, Yang Isaac, Pitts Lawrence H, Parsa Andrew T   Implications of cystic features in vestibular schwannomas of patients undergoing microsurgical resection Neurosurgery, 2011; 68(4): 874-80; discussion 879-80.
Sughrue Michael E, Kaur Rajwant, Kane Ari J, Rutkowski Martin J, Yang Isaac, Pitts Lawrence H, Tihan Tarik, Parsa Andrew T   Intratumoral hemorrhage and fibrosis in vestibular schwannoma: a possible mechanism for hearing loss Journal of neurosurgery, 2011; 114(2): 386-93.
Yang Isaac, Cho Jin Mo, Colen Chaim B, Li Gordon, Lim Michael, Sherman Jonathan H, Wang Vincent Yat   Neurosurgery concepts Surgical neurology international, 2011; 2(5): 173.
Choy Winward, Kim Won, Spasic Marko, Voth Brittany, Yew Andrew, Yang Isaac   Pineal cyst: a review of clinical and radiological features Neurosurgery clinics of North America, 2011; 22(3): 341-51, vii.
Kim Won, Stramotas Stephanie, Choy Winward, Dye Justin, Nagasawa Daniel, Yang Isaac   Prognostic factors for post-operative seizure outcomes after cavernous malformation treatment Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011; 18(7): 877-80.
Nagasawa Daniel, Yew Andrew, Spasic Marko, Choy Winward, Gopen Quinton, Yang Isaac   Survival outcomes for radiotherapy treatment of epidermoid tumors with malignant transformation Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011; .
Fong Brendan, Barkhoudarian Garni, Pezeshkian Patrick, Parsa Andrew T, Gopen Quinton, Yang Isaac   The molecular biology and novel treatments of vestibular schwannomas Journal of neurosurgery, 2011; 25(4): .
Choy Winward, Kim Won, Nagasawa Daniel, Stramotas Stephanie, Yew Andrew, Gopen Quinton, Parsa Andrew T, Yang Isaac   The molecular genetics and tumor pathogenesis of meningiomas and the future directions of meningioma treatments Neurosurgical focus, 2011; 30(5): E6.
Kim Won, Choy Winward, Dye Justin, Nagasawa Daniel, Safaee Michael, Fong Brendan, Yang Isaac   The tumor biology and molecular characteristics of medulloblastoma identifying prognostic factors associated with survival outcomes and prognosis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2011; 18(7): 886-90.
Yang Isaac, Sughrue Michael E, Han Seunggu J, Aranda Derick, Pitts Lawrence H, Cheung Steven W, Parsa Andrew T   A comprehensive analysis of hearing preservation after radiosurgery for vestibular schwannoma Journal of neurosurgery, 2010; 112(4): 851-9.
Sughrue Michael E, Kaur Rajwant, Rutkowski Martin J, Kane Ari J, Yang Isaac, Pitts Lawrence H, Parsa Andrew T   A critical evaluation of vestibular schwannoma surgery for patients younger than 40 years of age Neurosurgery, 2010; 67(6): 1646-53; discussion 1653-4.
Yang Isaac, Kim Won, De Salles Antonio, Bergsneider Marvin   A systematic analysis of disease control in acromegaly treated with radiosurgery Neurosurgical focus, 2010; 29(4): E13.
Jian Brian J, Bloch Orin G, Yang Isaac, Han Seunggu J, Aranda Derick, Tihan Tarik, Parsa Andrew T   Adjuvant radiation therapy and chondroid chordoma subtype are associated with a lower tumor recurrence rate of cranial chordoma Journal of neuro-oncology, 2010; 98(1): 101-8.
Yang Isaac, Liau Linda M   American Association for Cancer Research Genetics and Biology of Brain Cancers 2009, December 13-15, 2009, San Diego, CA Journal of neuro-oncology, 2010; 99(2): 297-306.
Han Seunggu J, Kaur Gurvinder, Yang Isaac, Lim Michael   Biologic principles of immunotherapy for malignant gliomas Neurosurgery clinics of North America, 2010; 21(1): 1-16.
Yang Isaac, Tihan Tarik, Han Seunggu J, Wrensch Margaret R, Wiencke John, Sughrue Michael E, Parsa Andrew T   CD8+ T-cell infiltrate in newly diagnosed glioblastoma is associated with long-term survival Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010; 17(11): 1381-5.
Han Seunggu J, Yang Isaac, Ahn Brian J, Otero Jose J, Tihan Tarik, McDermott Michael W, Berger Mitchel S, Prados Michael D, Parsa Andrew T   Clinical characteristics and outcomes for a modern series of primary gliosarcoma patients Cancer, 2010; 116(5): 1358-66.
Bloch Orin G, Jian Brian J, Yang Isaac, Han Seunggu J, Aranda Derick, Ahn Brian J, Parsa Andrew T   Cranial chondrosarcoma and recurrence Skull base : official journal of North American Skull Base Society ... [et al.], 2010; 20(3): 149-56.
Yang Isaac, Sughrue Michael E, Rutkowski Martin J, Kaur Rajwant, Ivan Michael E, Aranda Derick, Barani Igor J, Parsa Andrew T   Craniopharyngioma: a comparison of tumor control with various treatment strategies Neurosurgical focus, 2010; 28(4): E5.
Yang Isaac, Huh Nancy G, Smith Zachary A, Han Seunggu J, Parsa Andrew T   Distinguishing glioma recurrence from treatment effect after radiochemotherapy and immunotherapy Neurosurgery clinics of North America, 2010; 21(1): 181-6.
Sughrue Michael E, Yang Isaac, Aranda Derick, Kane Ari J, Parsa Andrew T   Hearing preservation rates after microsurgical resection of vestibular schwannoma Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010; 17(9): 1126-9.
Yang Isaac, Fang Shanna, Parsa Andrew T   Heat shock proteins in glioblastomas Neurosurgery clinics of North America, 2010; 21(1): 111-23.
Waldron James S, Yang Isaac, Han Seunggu, Tihan Tarik, Sughrue Michael E, Mills Steven A, Pieper Russell O, Parsa Andrew T   Implications for immunotherapy of tumor-mediated T-cell apoptosis associated with loss of the tumor suppressor PTEN in glioblastoma Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010; 17(12): 1543-7.
Kane Ari, Yang Isaac   Interferon-gamma in brain tumor immunotherapy Neurosurgery clinics of North America, 2010; 21(1): 77-86.
Yang Isaac, Wang Marilene B, Bergsneider Marvin   Making the transition from microsurgery to endoscopic trans-sphenoidal pituitary neurosurgery Neurosurgery clinics of North America, 2010; 21(4): 643-51, vi.
Kaur Gurvinder, Han Seunggu J, Yang Isaac, Crane Courtney   Microglia and central nervous system immunity Neurosurgery clinics of North America, 2010; 21(1): 43-51.
Jian Brian, Yang Isaac, Parsa Andrew T   Monitoring immune responses after glioma vaccine immunotherapy Neurosurgery clinics of North America, 2010; 21(1): 195-9.
Deipolyi Amy, Auguste Kurtis I, Yang Isaac, Tihan Tarik, Parsa Andrew T   Occipital ganglioglioma in an older adult Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010; 17(11): 1459-61.
Yang Isaac, Lim Michael   Preface Neurosurgery clinics of North America, 2010; 21(1): xv.
Sughrue Michael E, Yang Isaac, Rutkowski Martin J, Aranda Derick, Parsa Andrew T   Preservation of facial nerve function after resection of vestibular schwannoma British journal of neurosurgery, 2010; 24(6): 666-71.
Han Seunggu J, Yang Isaac, Tihan Tarik, Prados Michael D, Parsa Andrew T   Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity Journal of neuro-oncology, 2010; 96(3): 313-20.
Han Seunggu J, Yang Isaac, Otero Jose J, Ahn Brian J, Tihan Tarik, McDermott Michael W, Berger Mitchel S, Chang Susan M, Parsa Andrew T   Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients Journal of neurosurgery, 2010; 112(5): 990-6.
Han Seunggu J, Yang Isaac, Tihan Tarik, Chang Susan M, Parsa Andrew T   Secondary gliosarcoma: a review of clinical features and pathological diagnosis Journal of neurosurgery, 2010; 112(1): 26-32.
Fu Yongji, Bryan Hallberg S, Yang Isaac, Lai Kyle   Signal quality classification for an ambulatory monitoring system Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2010; 2010(5): 174-7.
Jian Brian J, Han Seunggu J, Yang Isaac, Waldron James S, Tihan Tarik, Parsa Andrew T   Surgical resection and adjuvant radiotherapy for a large pineal hemangiopericytoma Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010; 17(9): 1209-11.
Sughrue Michael E, Yang Isaac, Aranda Derick, Lobo Khadja, Pitts Lawrence H, Cheung Steven W, Parsa Andrew T   The natural history of untreated sporadic vestibular schwannomas: a comprehensive review of hearing outcomes Journal of neurosurgery, 2010; 112(1): 163-7.
Yang Isaac, Han Seunggu J, Kaur Gurvinder, Crane Courtney, Parsa Andrew T   The role of microglia in central nervous system immunity and glioma immunology Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010; 17(1): 6-10.
Sughrue Michael E, Kaur Rajwant, Kane Ari J, Rutkowski Martin J, Kaur Gurvinder, Yang Isaac, Pitts Lawrence H, Parsa Andrew T   The value of intraoperative facial nerve electromyography in predicting facial nerve function after vestibular schwannoma surgery Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2010; 17(7): 849-52.
Clark Aaron J, Ivan Michael E, Sughrue Michael E, Yang Isaac, Aranda Derick, Han Seunggu J, Kane Ari J, Parsa Andrew T   Tumor control after surgery and radiotherapy for pineocytoma Journal of neurosurgery, 2010; 113(2): 319-24.
Bloch Orin G, Jian Brian J, Yang Isaac, Han Seunggu J, Aranda Derick, Ahn Brian J, Parsa Andrew T   A systematic review of intracranial chondrosarcoma and survival Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009; 16(12): 1547-51.
Yang Isaac, Sughrue Michael E, Han Seunggu J, Fang Shanna, Aranda Derick, Cheung Steven W, Pitts Lawrence H, Parsa Andrew T   Facial nerve preservation after vestibular schwannoma Gamma Knife radiosurgery Journal of neuro-oncology, 2009; 93(1): 41-8.
Han Seunggu J, Ahn Brian J, Waldron James S, Yang Isaac, Fang Shanna, Crane Courtney A, Pieper Russell O, Parsa Andrew T   Gamma interferon-mediated superinduction of B7-H1 in PTEN-deficient glioblastoma: a paradoxical mechanism of immune evasion Neuroreport, 2009; 20(18): 1597-602.
Yang Isaac, Paik Elena, Huh Nancy G, Parsa Andrew T, Ames Christopher P   Giant thoracic schwannoma presenting with abrupt onset of abdominal pain: a case report Journal of medical case reports, 2009; 3(11): 88.
Yang Isaac, Aranda Derrick, Han Seunggu J, Chennupati Sravana, Sughrue Michael E, Cheung Steven W, Pitts Lawrence H, Parsa Andrew T   Hearing preservation after stereotactic radiosurgery for vestibular schwannoma: a systematic review Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2009; 16(6): 742-7.
Yang Isaac, Han Seunggu, Parsa Andrew T   Heat-shock protein vaccines as active immunotherapy against human gliomas Expert review of anticancer therapy, 2009; 9(11): 1577-82.
Sughrue Michael E, Yang Isaac, Kane Ari J, Rutkowski Martin J, Fang Shanna, James C David, Parsa Andrew T   Immunological considerations of modern animal models of malignant primary brain tumors Journal of translational medicine, 2009; 7(11): 84.
Yang Isaac, Aghi Manish K   New advances that enable identification of glioblastoma recurrence Nature reviews. Clinical oncology, 2009; 6(11): 648-57.
Sughrue Michael E, Yang Isaac, Han Seunggu J, Aranda Derick, Kane Ari J, Amoils Misha, Smith Zachary A, Parsa Andrew T   Non-audiofacial morbidity after Gamma Knife surgery for vestibular schwannoma Neurosurgical focus, 2009; 27(6): E4.
Chou Dean, Eltgroth Matthew, Yang Isaac, Lu Daniel, Manley Geoff   Rib head disarticulation for multilevel transpedicular thoracic corpectomies and expandable cage reconstruction Neurology India, 2009; 57(4): 469-74.
Yang Isaac, Delpolyi Amy, Sughrue Michael E, Rubenstein James, Bollen Andrew W, Parsa Andrew T   Sarcoidosis of the pineal gland: an unusual presentation of neurosarcoidosis Journal of neuro-oncology, 2009; 91(1): 113-6.
Yang Isaac, Barbaro Nicholas M   Advances in the radiosurgical treatment of epilepsy Epilepsy currents / American Epilepsy Society, 2008; 7(2): 31-5.
Yang Isaac, Lawton Michael T   Clipping of complex aneurysms with fenestration tubes: application and assessment of three types of clip techniques Neurosurgery, 2008; 62(5 Suppl 2): ONS371-8; discussion 378-9.
de Ipolyi Amy R, Yang Isaac, Buckley Anne, Barbaro Nicholas M, Cheung Steven W, Parsa Andrew T   Fluctuating response of a cystic vestibular schwannoma to radiosurgery: case report Neurosurgery, 2008; 62(5): E1164-5; discussion E1165.
Boudreau Christine R, Yang Isaac, Liau Linda M   Gliomas: advances in molecular analysis and characterization Surgical neurology, 2005; 64(4): 286-94; discussion 294.
Yang Isaac, Kremen Thomas J, Giovannone Adrian J, Paik Elena, Odesa Sylvia K, Prins Robert M, Liau Linda M   Modulation of major histocompatibility complex Class I molecules and major histocompatibility complex-bound immunogenic peptides induced by interferon-alpha and interferon-gamma treatment of human glioblastoma multiforme Journal of neurosurgery, 2004; 100(2): 310-9.
Bergsneider Marvin, Yang Isaac, Hu Xiao, McArthur David L, Cook Shon W, Boscardin W J   Relationship between valve opening pressure, body position, and intracranial pressure in normal pressure hydrocephalus: paradigm for selection of programmable valve pressure setting Neurosurgery, 2004; 55(4): 851-8; discussion 858-9.
Thakur Anjani, Yang Isaac, Lin Albert, Buchmiller-Crair Terry, Fonkalsrud Eric W   Management of ovarian cysts in women undergoing restorative proctocolectomy for ulcerative colitis The American surgeon, 2003; 69(4): 339-42.
Thakur Anjani, Yang Isaac, Lee Michael Y, Goel Arpan, Ashok Ashwin, Fonkalsrud Eric W   Increasing social capital via local networks: analysis in the context of a surgical practice The American surgeon, 2002; 68(9): 776-9.
Choy Winward, Spasic Marko, Pezeshkian Patrick, Fong Brendan M, Nagasawa Daniel T, Trang Andy, Mathur Ishani, De Salles Antonio, Gorgulho Alessandra, Selch Michael, Gopen Quinton S, Yang Isaac   Outcomes of stereotactic radiosurgery and stereotactic radiotherapy for the treatment of vestibular schwannoma Neurosurgery, 2013; 60 Suppl 1(3): 120-5.
Kim Moinay, Cheok Stephanie, Chung Lawrance K, Ung Nolan, Thill Kimberly, Voth Brittany, Kwon Do Hoon, Kim Jeong Hoon, Kim Chang Jin, Tenn Stephen, Lee Percy, Yang Isaac   Characteristics and treatments of large cystic brain metastasis: radiosurgery and stereotactic aspiration Brain tumor research and treatment, 2015; 3(1): 1-7.
Nicholas Sarah, Mathios Dimitris, Ruzevick Jacob, Jackson Christopher, Yang Isaac, Lim Michael   Current trends in glioblastoma multiforme treatment: radiation therapy and immune checkpoint inhibitors Brain tumor research and treatment, 2013; 1(1): 2-8.
Yang Isaac, Ung Nolan, Nagasawa Daniel T, Pelargos Panayiotis, Choy Winward, Chung Lawrance K, Thill Kim, Martin Neil A, Afsar-Manesh Nasim, Voth Brittany   Recent advances in the patient safety and quality initiatives movement: implications for neurosurgery Neurosurgery clinics of North America, 2015; 26(2): 301-15, xi.
Yew Andrew, Zarinkhou Golmah, Spasic Marko, Trang Andy, Gopen Quinton, Yang Isaac   Characteristics and management of superior semicircular canal dehiscence Journal of neurological surgery. Part B, Skull base, 2012; 73(6): 365-70.
Pelargos Panayiotis E, Nagasawa Daniel T, Ung Nolan, Chung Lawrance K, Thill Kimberly, Tenn Stephen, Gopen Quinton, Yang Isaac   Clinical characteristics and diagnostic imaging of cranial osteoblastoma Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015; 22(3): 445-9.
Mooney Kelly L, Choy Winward, Woodard Joslyn, Xian Rena R, Deal Taylor M, Kendle Ryan F, Said Jonathan, Grody Wayne, Yang Isaac   Primary central nervous system gamma delta cytotoxic T-cell lymphoma Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2016; 26(23): 138-40.
Kim Dong Gyu, Yang Isaac   Central neurocytomas. Preface Neurosurgery clinics of North America, 2015; 26(1): xiii.
Spasic Marko, Pelargos Panayiotis E, Barnette Natalie, Bhatt Nikhilesh S, Lee Seung James, Ung Nolan, Gopen Quinton, Yang Isaac   Incidental Meningiomas: Management in the Neuroimaging Era Neurosurgery clinics of North America, 2016; 27(2): 229-38.
Yang Isaac, Ung Nolan, Chung Lawrance K, Nagasawa Daniel T, Thill Kimberly, Park Junmook, Tenn Stephen   Clinical manifestations of central neurocytoma Neurosurgery clinics of North America, 2015; 26(1): 5-10.
Li Gordon, Dahdaleh Nader S, Germanwala Anand V, Lam Sandi, Choy Winward, Smith Zachary A, Yang Isaac   Key perspectives on donepezil following brain irradiation, sacroiliac joint fusion, indocyanine green fluorescence endoscope in endonasal transsphenoidal surgery, postconcussion syndrome in young athletes Surgical neurology international, 2015; 6(Suppl 26): S647-50.
Choy Winward, Bohnen Angela M, Pelargos Panayiotis, Lam Sandi, Yang Isaac, Smith Zachary A   Neurosurgery concepts: Key perspectives on deferoxamine and chronic hydrocephalus from intraventricular hemorrhage, laboratory dissection training in neurosurgical residency, tetanus toxoid and dendritic cell vaccines for glioblastoma, and intracranial hypertension after surgery for craniosynostosis Surgical neurology international, 2015; 6(Suppl 26): 139.
Chung Lawrance K, Ung Nolan, Spasic Marko, Nagasawa Daniel T, Pelargos Panayiotis E, Thill Kimberly, Voth Brittany, Hirt Daniel, Gopen Quinton, Yang Isaac   Clinical outcomes of middle fossa craniotomy for superior semicircular canal dehiscence repair Journal of neurosurgery, 2016; 144(9): 1-7.
Lam Sandi, Li Gordon, Zada Gabriel, Pelargos Panayiotis, Choy Winward, Yang Isaac, Smith Zachary A   Neurosurgery Concepts: Key perspectives on quality of life in children with spina bifida, cilengitide for the treatment of newly diagnosed glioblastoma, surgery and stereotactic radiosurgery in the management of intracranial metastasis, Gamma Knife radiosurgery in patients with Neurofibromatosis Type 2, patient misconceptions on the diagnosis and treatment of lumbar spondylosis Surgical neurology international, 2015; 6(Suppl 26): 110.
Choy Winward, Terterov Sergei, Ung Nolan, Kaprealian Tania, Trang Andy, DeSalles Antonio, Chung Lawrance K, Martin Neil, Selch Michael, Bergsneider Marvin, Yong William, Yang Isaac   Adjuvant Stereotactic Radiosurgery and Radiation Therapy for the Treatment of Intracranial Chordomas Journal of neurological surgery. Part B, Skull base, 2016; 77(1): 38-46.
Sherman Johnathan H, Dahdaleh Nader S, Pelargos Panayiotis, Lam Sandi, Choy Winward, Yang Isaac, Smith Zachary A   Neurosurgery Concepts: Key perspectives on C2 nerve root transection following C1 lateral mass screw fixation, choroid plexus cauterization in infants with hydrocephalus, quality of life following treatment of vestibular schwannoma, dynamic magnetic resonance imaging for glioblastoma pseudoprogression, cost-utility analysis of lumbar spinal stenosis treatment Surgical neurology international, 2015; 6(Suppl 26): 108.
Magaki Shino, Chang Edward, Hammond Robert R, Yang Isaac, Mackenzie Ian R A, Chou Benedict T, Choi Soo I, Jen Joanna C, Pope Whitney B, Bell David A, Vinters Harry V   Two cases of rheumatoid meningitis Neuropathology : official journal of the Japanese Society of Neuropathology, 2016; 36(1): 93-102.
Cho Jin Mo, Colen Chaim B, Li Gordon, Wang Vincent Yat, Dahdaleh Nader, Choy Winward, Yang Isaac, Smith Zachary A   Neurosurgery Concepts: Key perspectives on Traumatic Brain Injury, New Treatments for Glioblastoma, Hemicraniectomy for Extensive Middle-Cerebral-Artery Stroke, Minimally Invasive Spine Surgery and Lumbar Epidural Injections for Radiculopathy Surgical neurology international, 2015; 6(Suppl 26): 98.
Spasic Marko, Trang Andy, Chung Lawrance K, Ung Nolan, Thill Kimberly, Zarinkhou Golmah, Gopen Quinton S, Yang Isaac   Clinical Characteristics of Posterior and Lateral Semicircular Canal Dehiscence Journal of neurological surgery. Part B, Skull base, 2015; 76(6): 421-5.
Li Gordon, Sherman Jonathan H, Cho Jin Mo, Lim Michael, Khalessi Alexander A, Colen Chaim B, Kim Chae Yong, Wang Vincent Yat, Zada Gabriel, Smith Zachary A, Yang Isaac   Neurosurgery concepts: Key perspectives on dendritic cell vaccines, metastatic tumor treatment, and radiosurgery Surgical neurology international, 2015; 6(Suppl 26): 6.
Dye Justin A, Rees Galya, Yang Isaac, Vespa Paul M, Martin Neil A, Vinters Harry V   Neuropathologic analysis of hematomas evacuated from patients with spontaneous intracerebral hemorrhage Neuropathology : official journal of the Japanese Society of Neuropathology, 2014; 34(3): 253-60.
Kan Peter, Duckworth Edward, Germanwala Anand V, Pelargos Panayiotis, Cho Jin Mo, Choy Winward, Smith Zachary A, Yang Isaac   Neurosurgery concepts: Key perspectives on embolectomy for stroke with emergent large vessel occlusion (MR CLEAN), endonasal endoscopic craniopharyngioma resection, gamma knife radiosurgery for meningiomas, therapeutic hypothermia for severe traumatic brain injury Surgical neurology international, 2015; 6(Suppl 26): 165.
Choy Winward, Terterov Sergei, Kaprealian Tania B, Trang Andy, Ung Nolan, DeSalles Antonio, Chung Lawrance K, Martin Neil, Selch Michael, Bergsneider Marvin, Vinters Harry V, Yong William H, Yang Isaac   Predictors of recurrence following resection of intracranial chordomas Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015; 22(11): 1792-6.
Ooi Yinn Cher, Tran Patrick, Ung Nolan, Thill Kimberly, Trang Andy, Fong Brendan M, Nagasawa Daniel T, Lim Michael, Yang Isaac   The role of regulatory T-cells in glioma immunology Clinical neurology and neurosurgery, 2014; 119(3): 125-32.
Fong Christina, Nagasawa Daniel T, Chung Lawrance K, Voth Brittany, Cremer Nicole, Thill Kimberly, Ung Nolan, Gopen Quinton, Yang Isaac   Systematic Analysis of Outcomes for Surgical Resection and Radiotherapy in Patients with Papillary Meningioma Journal of neurological surgery. Part B, Skull base, 2015; 76(4): 252-6.
Peng Kevin A, Ahmed Sameer, Yang Isaac, Gopen Quinton   Temporal bone fracture causing superior semicircular canal dehiscence Case reports in otolaryngology, 2014; 2014(3): 817291.
Voth Brittany, Nagasawa Daniel T, Pelargos Panayiotis E, Chung Lawrance K, Ung Nolan, Gopen Quinton, Tenn Stephen, Kamei Daniel T, Yang Isaac   Transferrin receptors and glioblastoma multiforme: Current findings and potential for treatment Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2015; 22(7): 1071-6.
Sughrue Michael E, Yang Isaac, Han Seunggu J, Aranda Derick, Kane Ari J, Amoils Misha, Smith Zachary A, Parsa Andrew T   Non-audiofacial morbidity after Gamma Knife surgery for vestibular schwannoma Journal of neurosurgery, 2013; 119 Suppl(3): E4.
Ung Nolan, Yang Isaac   Nanotechnology to augment immunotherapy for the treatment of glioblastoma multiforme Journal of neuro-oncology, 2015; 123(3): 473-81.
Yang Isaac, Sughrue Michael E, Han Seunggu J, Aranda Derick, Pitts Lawrence H, Cheung Steven W, Parsa Andrew T   A comprehensive analysis of hearing preservation after radiosurgery for vestibular schwannoma: clinical article Journal of neurosurgery, 2013; 119 Suppl(3): 851-9.

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