A Short Biography:
My research interests center around novel therapeutics for pediatric patients with central nervous system tumors. Specifically, my research focuses on stimulating the immune system to attack brain tumors (immunotherapy). My current projects include investigating means by which to combine immunotherapy with other biologic and cytotoxic therapies to achieve synergistic responses. I am also interested in the molecular signalling pathways that define putative brain tumor-initiating cells. I also participate in a variety of clinical trials involving pediatric hematology and oncology.
Publications:
A selected list of publications:
Mehta Rupal I, Cutler Aaron R, Lasky Joseph L, Yong William H, Lerner Jason T, Hirota Brandon K, Salamon Noriko, Mathern Gary W, Vinters Harry V
"Primary" leptomeningeal medulloblastoma
Human pathology,
2009; 40(11):
1661-5.
Guo Wei, Lasky Joseph L, Chang Chun-Ju, Mosessian Sherly, Lewis Xiaoman, Xiao Yun, Yeh Jennifer E, Chen James Y, Iruela-Arispe M Luisa, Varella-Garcia Marileila, Wu Hong
Multi-genetic events collaboratively contribute to Pten-null leukaemia
stem-cell formation
Nature,
2008; 453(7194):
529-33.
Guo Wei, Lasky Joseph L, Wu Hong
Cancer stem cells
Pediatric research,
2006; 59(4 Pt 2):
59R-64R.