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RESEARCH

Steve Horvath, Ph.D., Sc.D.

Contact Information:

Work Phone Number:

(310) 825-9299

Laboratory Address:

Gonda 5545

UNITED STATES

Mailing Address:

Department of Human Genetics
Gonda Research Center
David Geffen School of Medicine
695 Charles E. Young Drive South
Box 708822
Los Angeles, CA 90095
UNITED STATES

Work Address:

Gonda 4357A
Campus - 708822
CA
UNITED STATES
Office
Gonda
Los Angeles, CA 90095
UNITED STATES
Laboratory
Gonda
Los Angeles, CA 90095
UNITED STATES

Work Email Address:

shorvath@mednet.ucla.edu

Professor, Human Genetics

Biostatistics

UCLA Program on Genomics and Nutrition


A Short Biography:

Steve Horvath received a Ph.D. in Mathematics from the University of North Carolina, Chapel Hill in 1995 and a Doctorate of Science in Biostatistics from the Harvard School of Public Health in 2000.

Detailed Biography:

Steve Horvath is a bioinformatician whose research area lies at the intersection of biostatistics,computational biology, cancer research, genetics, epidemiology, machine learning, and systems biology. His group applies data mining methods to study a broad spectrum of diseases, e.g. aging research, cancer, cardiovascular disease, HIV, Huntington's disease, neurodegenerative diseases. He became a full professor in Human Genetics and Biostatistics in 2009. He develops and applies methods for analyzing and integrating gene expression-, DNA methylation-, microRNA, genetic marker-, and complex phenotype data. In particular, his group developed weighted correlation network analysis (also known as weighted gene co-expression network analysis WGCNA), which is a systems biologic data analysis method for analyzing high dimensional "-omics" data. He works on all aspects of biomarker development.

Selected Publications:

Xue Zhigang, Huang Kevin, Cai Chaochao, Cai Lingbo, Jiang Chun-yan, Feng Yun, Liu Zhenshan, Zeng Qiao, Cheng Liming, Sun Yi E, Liu Jia-yin, Horvath Steve, Fan Guoping Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing. Nature. 2013; 500(7464): 593-7.
Ranola John Michael, Langfelder Peter, Lange Kenneth, Horvath Steve Cluster and propensity based approximation of a network. BMC systems biology. 2013; 7(4): 21.
Miller Jeremy A, Woltjer Randall L, Goodenbour Jeff M, Horvath Steve, Geschwind Daniel H Genes and pathways underlying regional and cell type changes in Alzheimer's disease. Genome medicine. 2013; 5(5): 48.
Ho Melissa E, Quek Sue-Ing, True Lawrence D, Morrissey Colm, Corey Eva, Vessella Robert L, Dumpit Ruth, Nelson Peter S, Maresh Erin L, Mah Vei, Alavi Mohammed, Kim Sara R, Bagryanova Lora, Horvath Steve, Chia David, Goodglick Lee, Liu Alvin Y Prostate cancer cell phenotypes based on AGR2 and CD10 expression. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2013; 26(6): 849-59.
Song Lin, Langfelder Peter, Horvath Steve Random generalized linear model: a highly accurate and interpretable ensemble predictor. BMC bioinformatics. 2013; 14(4): 5.
Levine Andrew J, Miller Jeremy A, Shapshak Paul, Gelman Benjamin, Singer Elyse J, Hinkin Charles H, Commins Deborah, Morgello Susan, Grant Igor, Horvath Steve Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer's disease. BMC medical genomics. 2013; 6(4): 4.
Langfelder Peter, Mischel Paul S, Horvath Steve When is hub gene selection better than standard meta-analysis?. PloS one. 2013; 8(4): e61505.
Haas Blake E, Horvath Steve, Pietiläinen Kirsi H, Cantor Rita M, Nikkola Elina, Weissglas-Volkov Daphna, Rissanen Aila, Civelek Mete, Cruz-Bautista Ivette, Riba Laura, Kuusisto Johanna, Kaprio Jaakko, Tusie-Luna Teresa, Laakso Markku, Aguilar-Salinas Carlos A, Pajukanta Päivi Adipose co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes. BMC medical genomics. 2012; 5(4): 61.
Hilliard Austin T, Miller Julie E, Horvath Steve, White Stephanie A Distinct neurogenomic states in basal ganglia subregions relate differently to singing behavior in songbirds. PLoS computational biology. 2012; 8(11): e1002773.
de Jong Simone, Boks Marco P M, Fuller Tova F, Strengman Eric, Janson Esther, de Kovel Carolien G F, Ori Anil P S, Vi Nancy, Mulder Flip, Blom Jan Dirk, Glenthøj Birte, Schubart Chris D, Cahn Wiepke, Kahn René S, Horvath Steve, Ophoff Roel A A gene co-expression network in whole blood of schizophrenia patients is independent of antipsychotic-use and enriched for brain-expressed genes. PloS one. 2012; 7(6): e39498.
Luykx Jurjen J, Bakker Steven C, Lentjes Eef, Boks Marco P M, van Geloven Nan, Eijkemans Marinus J C, Janson Esther, Strengman Eric, de Lepper Anne M, Westenberg Herman, Klopper Kai E, Hoorn Hendrik J, Gelissen Harry P M M, Jordan Julian, Tolenaar Noortje M, van Dongen Eric P A, Michel Bregt, Abramovic Lucija, Horvath Steve, Kappen Teus, Bruins Peter, Keijzers Peter, Borgdorff Paul, Ophoff Roel A, Kahn René S Season of sampling and season of birth influence serotonin metabolite levels in human cerebrospinal fluid. PloS one. 2012; 7(2): e30497.
Hawrylycz Michael J, Lein Ed S, Guillozet-Bongaarts Angela L, Shen Elaine H, Ng Lydia, Miller Jeremy A, van de Lagemaat Louie N, Smith Kimberly A, Ebbert Amanda, Riley Zackery L, Abajian Chris, Beckmann Christian F, Bernard Amy, Bertagnolli Darren, Boe Andrew F, Cartagena Preston M, Chakravarty M Mallar, Chapin Mike, Chong Jimmy, Dalley Rachel A, Daly Barry David, Dang Chinh, Datta Suvro, Dee Nick, Dolbeare Tim A, Faber Vance, Feng David, Fowler David R, Goldy Jeff, Gregor Benjamin W, Haradon Zeb, Haynor David R, Hohmann John G, Horvath Steve, Howard Robert E, Jeromin Andreas, Jochim Jayson M, Kinnunen Marty, Lau Christopher, Lazarz Evan T, Lee Changkyu, Lemon Tracy A, Li Ling, Li Yang, Morris John A, Overly Caroline C, Parker Patrick D, Parry Sheana E, Reding Melissa, Royall Joshua J, Schulkin Jay, Sequeira Pedro Adolfo, Slaughterbeck Clifford R, Smith Simon C, Sodt Andy J, Sunkin Susan M, Swanson Beryl E, Vawter Marquis P, Williams Derric, Wohnoutka Paul, Zielke H Ronald, Geschwind Daniel H, Hof Patrick R, Smith Stephen M, Koch Christof, Grant Seth G N, Jones Allan R An anatomically comprehensive atlas of the adult human brain transcriptome. Nature. 2012; 489(7416): 391-9.
Weiss James N, Karma Alain, MacLellan W Robb, Deng Mario, Rau Christoph D, Rees Colin M, Wang Jessica, Wisniewski Nicholas, Eskin Eleazar, Horvath Steve, Qu Zhilin, Wang Yibin, Lusis Aldons J "Good enough solutions" and the genetics of complex diseases. Circulation research. 2012; 111(4): 493-504.
Horvath Steve, Zhang Yafeng, Langfelder Peter, Kahn René S, Boks Marco Pm, van Eijk Kristel, van den Berg Leonard H, Ophoff Roel A Aging effects on DNA methylation modules in human brain and blood tissue. Genome biology. 2012; 13(10): R97.
Song Lin, Langfelder Peter, Horvath Steve Comparison of co-expression measures: mutual information, correlation, and model based indices. BMC bioinformatics. 2012; 13(4): 328.
Vivanco Igor, Robins H Ian, Rohle Daniel, Campos Carl, Grommes Christian, Nghiemphu Phioanh Leia, Kubek Sara, Oldrini Barbara, Chheda Milan G, Yannuzzi Nicolas, Tao Hui, Zhu Shaojun, Iwanami Akio, Kuga Daisuke, Dang Julie, Pedraza Alicia, Brennan Cameron W, Heguy Adriana, Liau Linda M, Lieberman Frank, Yung W K Alfred, Gilbert Mark R, Reardon David A, Drappatz Jan, Wen Patrick Y, Lamborn Kathleen R, Chang Susan M, Prados Michael D, Fine Howard A, Horvath Steve, Wu Nian, Lassman Andrew B, DeAngelis Lisa M, Yong William H, Kuhn John G, Mischel Paul S, Mehta Minesh P, Cloughesy Timothy F, Mellinghoff Ingo K Differential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitors. Cancer discovery. 2012; 2(5): 458-71.
Langfelder Peter, Horvath Steve Fast R Functions for Robust Correlations and Hierarchical Clustering. Journal of statistical software. 2012; 46(11): .
van Eijk Kristel R, de Jong Simone, Boks Marco P M, Langeveld Terry, Colas Fabrice, Veldink Jan H, de Kovel Carolien G F, Janson Esther, Strengman Eric, Langfelder Peter, Kahn René S, van den Berg Leonard H, Horvath Steve, Ophoff Roel A Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects. BMC genomics. 2012; 13(4): 636.
Diekstra Frank P, Saris Christiaan G J, van Rheenen Wouter, Franke Lude, Jansen Ritsert C, van Es Michael A, van Vught Paul W J, Blauw Hylke M, Groen Ewout J N, Horvath Steve, Estrada Karol, Rivadeneira Fernando, Hofman Albert, Uitterlinden Andre G, Robberecht Wim, Andersen Peter M, Melki Judith, Meininger Vincent, Hardiman Orla, Landers John E, Brown Robert H, Shatunov Aleksey, Shaw Christopher E, Leigh P Nigel, Al-Chalabi Ammar, Ophoff Roel A, van den Berg Leonard H, Veldink Jan H Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS. PloS one. 2012; 7(4): e35333.
Hilliard Austin T, Miller Julie E, Fraley Elizabeth R, Horvath Steve, White Stephanie A Molecular microcircuitry underlies functional specification in a basal ganglia circuit dedicated to vocal learning. Neuron. 2012; 73(3): 537-52.
Huynh Thu P, Mah Vei, Sampson Valerie B, Chia David, Fishbein Michael C, Horvath Steve, Alavi Mohammad, Wu Debbie C, Harper Jeffrey, Sarafian Ted, Dubinett Steven M, Langhans Sigrid A, Goodglick Lee, Rajasekaran Ayyappan K Na,K-ATPase is a target of cigarette smoke and reduced expression predicts poor patient outcome of smokers with lung cancer. American journal of physiology. Lung cellular and molecular physiology. 2012; 302(11): L1150-8.
Oldham Michael C, Langfelder Peter, Horvath Steve Network methods for describing sample relationships in genomic datasets: application to Huntington's disease. BMC systems biology. 2012; 6(1): 63.
Shirasaki Dyna I, Greiner Erin R, Al-Ramahi Ismael, Gray Michelle, Boontheung Pinmanee, Geschwind Daniel H, Botas Juan, Coppola Giovanni, Horvath Steve, Loo Joseph A, Yang X William Network organization of the huntingtin proteomic interactome in mammalian brain. Neuron. 2012; 75(1): 41-57.
Leuchter Andrew F, Cook Ian A, Hunter Aimee M, Cai Chaochao, Horvath Steve Resting-state quantitative electroencephalography reveals increased neurophysiologic connectivity in depression. PloS one. 2012; 7(2): e32508.
Horvath Steve, Nazmul-Hossain Abu Nm, Pollard Rodney Pe, Kroese Frans Gm, Vissink Arjan, Kallenberg Cees Gm, Spijkervet Fred Kl, Bootsma Hendrika, Michie Sara A, Gorr Sven U, Peck Ammon B, Cai Chaochao, Zhou Hui, Wong David Tw Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model. Arthritis research & therapy. 2012; 14(6): R238.
Gorr Sven-Ulrik, Wennblom Trevor J, Horvath Steve, Wong David T W, Michie Sara A Text-mining applied to autoimmune disease research: the Sjögren's syndrome knowledge base. BMC musculoskeletal disorders. 2012; 13(1): 119.
Langfelder Peter, Castellani Lawrence W, Zhou Zhiqiang, Paul Eric, Davis Richard, Schadt Eric E, Lusis Aldons J, Horvath Steve, Mehrabian Margarete A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. Biochimica et biophysica acta. 2011; 76(9): .
Bocklandt Sven, Lin Wen, Sehl Mary E, Sánchez Francisco J, Sinsheimer Janet S, Horvath Steve, Vilain Eric Epigenetic predictor of age. PloS one. 2011; 6(6): e14821.
Mah Vei, Marquez Diana, Alavi Mohammad, Maresh Erin L, Zhang Li, Yoon Nam, Horvath Steve, Bagryanova Lora, Fishbein Michael C, Chia David, Pietras Richard, Goodglick Lee Expression levels of estrogen receptor beta in conjunction with aromatase predict survival in non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands). 2011; 474(7351): .
Huerta-Yepez Sara, Yoon Nam K, Hernandez-Cueto Angeles, Mah Vei, Rivera-Pazos Clara M, Chatterjee Devasis, Vega Mario I, Maresh Erin L, Horvath Steve, Chia David, Bonavida Benjamin, Goodglick Lee Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival. BMC cancer. 2011; 11(9): 259.
Wang Anyou, Huang Kevin, Shen Yin, Xue Zhigang, Cai Chaochao, Horvath Steve, Fan Guoping Functional modules distinguish human induced pluripotent stem cells from embryonic stem cells. Stem cells and development. 2011; 20(11): 1937-50.
Dewey Frederick E, Perez Marco V, Wheeler Matthew T, Watt Clifton, Spin Joshua, Langfelder Peter, Horvath Steve, Hannenhalli Sridhar, Cappola Thomas P, Ashley Euan A Gene coexpression network topology of cardiac development, hypertrophy, and failure. Circulation. Cardiovascular genetics. 2011; 4(1): 26-35.
Park Christopher C, Gale Greg D, de Jong Simone, Ghazalpour Anatole, Bennett Brian J, Farber Charles R, Langfelder Peter, Lin Andy, Khan Arshad H, Eskin Eleazar, Horvath Steve, Lusis Aldons J, Ophoff Roel A, Smith Desmond J Gene networks associated with conditional fear in mice identified using a systems genetics approach. BMC systems biology. 2011; 5(7351): 43.
Langfelder Peter, Luo Rui, Oldham Michael C, Horvath Steve Is my network module preserved and reproducible?. PLoS computational biology. 2011; 7(1): e1001057.
Marquez-Garban Diana C, Mah Vei, Alavi Mohammad, Maresh Erin L, Chen Hsiao-Wang, Bagryanova Lora, Horvath Steve, Chia David, Garon Edward, Goodglick Lee, Pietras Richard J Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer. Steroids. 2011; 76(9): 910-20.
Presson Angela P, Yoon Nam K, Bagryanova Lora, Mah Vei, Alavi Mohammad, Maresh Erin L, Rajasekaran Ayyappan K, Goodglick Lee, Chia David, Horvath Steve Protein expression based multimarker analysis of breast cancer samples. BMC cancer. 2011; 11(9): 230.
Miller Jeremy A, Cai Chaochao, Langfelder Peter, Geschwind Daniel H, Kurian Sunil M, Salomon Daniel R, Horvath Steve Strategies for aggregating gene expression data: the collapseRows R function. BMC bioinformatics. 2011; 12(11): 322.
Voineagu Irina, Wang Xinchen, Johnston Patrick, Lowe Jennifer K, Tian Yuan, Horvath Steve, Mill Jonathan, Cantor Rita M, Blencowe Benjamin J, Geschwind Daniel H Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature. 2011; 474(7351): 380-4.
Manuyakorn Ananya, Paulus Rebecca, Farrell James, Dawson Nicole A, Tze Sheila, Cheung-Lau Gardenia, Hines Oscar Joe, Reber Howard, Seligson David B, Horvath Steve, Kurdistani Siavash K, Guha Chandhan, Dawson David W Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2010; 28(8): 1358-65.
Mumford Jeanette A, Horvath Steve, Oldham Michael C, Langfelder Peter, Geschwind Daniel H, Poldrack Russell A Detecting network modules in fMRI time series: a weighted network analysis approach. NeuroImage. 2010; 52(4): 1465-76.
Maresh Erin L, Mah Vei, Alavi Mohammad, Horvath Steve, Bagryanova Lora, Liebeskind Emily S, Knutzen Laura A, Zhou Yong, Chia David, Liu Alvin Y, Goodglick Lee Differential expression of anterior gradient gene AGR2 in prostate cancer. BMC cancer. 2010; 10(6): 680.
Miller Jeremy A, Horvath Steve, Geschwind Daniel H Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(28): 12698-703.
Yoon Nam K, Maresh Erin L, Elshimali Yahya, Li Ai, Horvath Steve, Seligson David B, Chia David, Goodglick Lee Elevated MED28 expression predicts poor outcome in women with breast cancer. BMC cancer. 2010; 10(28): 335.
Habeeb Omar, Goodglick Lee, Soslow Robert A, Rao Rajiv G, Gordon Lynn K, Schirripa Osvaldo, Horvath Steve, Braun Jonathan, Seligson David B, Wadehra Madhuri Epithelial membrane protein-2 expression is an early predictor of endometrial cancer development. Cancer. 2010; 116(20): 4718-26.
de Jong Simone, Fuller Tova F, Janson Esther, Strengman Eric, Horvath Steve, Kas Martien J H, Ophoff Roel A Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background. BMC genomics. 2010; 11(8): 20.
Le Brandon H, Cheng Chen, Bui Anhthu Q, Wagmaister Javier A, Henry Kelli F, Pelletier Julie, Kwong Linda, Belmonte Mark, Kirkbride Ryan, Horvath Steve, Drews Gary N, Fischer Robert L, Okamuro Jack K, Harada John J, Goldberg Robert B Global analysis of gene activity during Arabidopsis seed development and identification of seed-specific transcription factors. Proceedings of the National Academy of Sciences of the United States of America. 2010; 107(18): 8063-70.
Yoon Nam K, Maresh Erin L, Shen Dejun, Elshimali Yahya, Apple Sophia, Horvath Steve, Mah Vei, Bose Shikha, Chia David, Chang Helena R, Goodglick Lee Higher levels of GATA3 predict better survival in women with breast cancer. Human pathology. 2010; 41(12): 1794-801.
Cai Chaochao, Langfelder Peter, Fuller Tova F, Oldham Michael C, Luo Rui, van den Berg Leonard H, Ophoff Roel A, Horvath Steve Is human blood a good surrogate for brain tissue in transcriptional studies?. BMC genomics. 2010; 11(12): 589.
Ooi Aik T, Mah Vei, Nickerson Derek W, Gilbert Jennifer L, Ha Vi Luan, Hegab Ahmed E, Horvath Steve, Alavi Mohammad, Maresh Erin L, Chia David, Gower Adam C, Lenburg Marc E, Spira Avrum, Solis Luisa M, Wistuba Ignacio I, Walser Tonya C, Wallace William D, Dubinett Steven M, Goodglick Lee, Gomperts Brigitte N Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer research. 2010; 70(16): 6639-48.
Plaisier Christopher L, Horvath Steve, Huertas-Vazquez Adriana, Cruz-Bautista Ivette, Herrera Miguel F, Tusie-Luna Teresa, Aguilar-Salinas Carlos, Pajukanta Päivi A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia. PLoS genetics. 2009; 5(9): e1000642.
Farber Charles R, van Nas Atila, Ghazalpour Anatole, Aten Jason E, Doss Sudheer, Sos Brandon, Schadt Eric E, Ingram-Drake Leslie, Davis Richard C, Horvath Steve, Smith Desmond J, Drake Thomas A, Lusis Aldons J An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2009; 24(1): 105-16.
Kurian Sunil M, Heilman Raymond, Mondala Tony S, Nakorchevsky Aleksey, Hewel Johannes A, Campbell Daniel, Robison Elizabeth H, Wang Lin, Lin Wen, Gaber Lillian, Solez Kim, Shidban Hamid, Mendez Robert, Schaffer Randolph L, Fisher Jonathan S, Flechner Stuart M, Head Steve R, Horvath Steve, Yates John R, Marsh Christopher L, Salomon Daniel R Biomarkers for early and late stage chronic allograft nephropathy by proteogenomic profiling of peripheral blood. PloS one. 2009; 4(7): e6212.
Kleefuss-Lie Ailing, Friedl Waltraut, Cichon Sven, Haug Karsten, Warnstedt Maike, Alekov Alexi, Sander Thomas, Ramirez Alfredo, Poser Barbara, Maljevic Snezana, Hebeisen Simon, Kubisch Christian, Rebstock Johannes, Horvath Steve, Hallmann Kerstin, Dullinger Jörn S, Rau Birgit, Haverkamp Fritz, Beyenburg Stefan, Schulz Herbert, Janz Dieter, Giese Bernd, Müller-Newen Gerhard, Propping Peter, Elger Christian E, Fahlke Christoph, Lerche Holger CLCN2 variants in idiopathic generalized epilepsy. Nature genetics. 2009; 41(9): 954-5.
Guo Deliang, Prins Robert M, Dang Julie, Kuga Daisuke, Iwanami Akio, Soto Horacio, Lin Kelly Y, Huang Tiffany T, Akhavan David, Hock M Benjamin, Zhu Shaojun, Kofman Ava A, Bensinger Steve J, Yong William H, Vinters Harry V, Horvath Steve, Watson Andrew D, Kuhn John G, Robins H Ian, Mehta Minesh P, Wen Patrick Y, DeAngelis Lisa M, Prados Michael D, Mellinghoff Ingo K, Cloughesy Timothy F, Mischel Paul S EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. Science signaling. 2009; 2(101): ra82.
van Nas Atila, Guhathakurta Debraj, Wang Susanna S, Yehya Nadir, Horvath Steve, Zhang Bin, Ingram-Drake Leslie, Chaudhuri Gautam, Schadt Eric E, Drake Thomas A, Arnold Arthur P, Lusis Aldons J Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. Endocrinology. 2009; 150(3): 1235-49.
Farber Charles R, Aten Jason E, Farber Emily A, de Vera Vincent, Gularte Rodrigo, Islas-Trejo Alma, Wen Pengzi, Horvath Steve, Lucero Michael, Lusis Aldons J, Medrano Juan F Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling. Physiological genomics. 2009; 37(3): 294-302.
Seligson David B, Horvath Steve, McBrian Matthew A, Mah Vei, Yu Hong, Tze Sheila, Wang Qun, Chia David, Goodglick Lee, Kurdistani Siavash K Global levels of histone modifications predict prognosis in different cancers. The American journal of pathology. 2009; 174(5): 1619-28.
Yoon Nam K, Seligson David B, Chia David, Elshimali Yahya, Sulur Giri, Li Ai, Horvath Steve, Maresh Erin, Mah Vei, Bose Shikha, Bonavida Benjamin, Goodglick Lee Higher expression levels of 14-3-3sigma in ductal carcinoma in situ of the breast predict poorer outcome. Cancer biomarkers : section A of Disease markers. 2009; 5(4): 215-24.
Li Ai, Horvath Steve Network module detection: Affinity search technique with the multi-node topological overlap measure. BMC research notes. 2009; 2(9): 142.
Laks Dan R, Masterman-Smith Michael, Visnyei Koppany, Angenieux Brigitte, Orozco Nicholas M, Foran Ian, Yong William H, Vinters Harry V, Liau Linda M, Lazareff Jorge A, Mischel Paul S, Cloughesy Timothy F, Horvath Steve, Kornblum Harley I Neurosphere formation is an independent predictor of clinical outcome in malignant glioma. Stem cells (Dayton, Ohio). 2009; 27(4): 980-7.
Haug Karsten, Warnstedt Maike, Alekov Alexi K, Sander Thomas, Ramírez Alfredo, Poser Barbara, Maljevic Snezana, Hebeisen Simon, Kubisch Christian, Rebstock Johannes, Horvath Steve, Hallmann Kerstin, Dullinger Joern S, Rau Birgit, Haverkamp Fritz, Beyenburg Stefan, Schulz Herbert, Janz Dieter, Giese Bernd, Müller-Newen Gerhard, Propping Peter, Elger Christian E, Fahlke Christoph, Lerche Holger Retraction: Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies. Nature genetics. 2009; 41(9): 1043.
Sridharan Rupa, Tchieu Jason, Mason Mike J, Yachechko Robin, Kuoy Edward, Horvath Steve, Zhou Qing, Plath Kathrin Role of the murine reprogramming factors in the induction of pluripotency. Cell. 2009; 136(2): 364-77.
Mason Mike J, Fan Guoping, Plath Kathrin, Zhou Qing, Horvath Steve Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. BMC genomics. 2009; 10(9): 327.
Hu Shen, Zhou Michael, Jiang Jiang, Wang Jianghua, Elashoff David, Gorr Sven, Michie Sara A, Spijkervet Fred K L, Bootsma Hendrika, Kallenberg Cees G M, Vissink Arjan, Horvath Steve, Wong David T Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands. Arthritis and rheumatism. 2009; 60(1): 81-92.
Winden Kellen D, Oldham Michael C, Mirnics Karoly, Ebert Philip J, Swan Christo H, Levitt Pat, Rubenstein John L, Horvath Steve, Geschwind Daniel H The organization of the transcriptional network in specific neuronal classes. Molecular systems biology. 2009; 5(1): 291.
MacLennan Nicole K, Dong Jun, Aten Jason E, Horvath Steve, Rahib Lola, Ornelas Loren, Dipple Katrina M, McCabe Edward R B Weighted gene co-expression network analysis identifies biomarkers in glycerol kinase deficient mice. Molecular genetics and metabolism. 2009; 98(1-2): 203-14.
Saris Christiaan G J, Horvath Steve, van Vught Paul W J, van Es Michael A, Blauw Hylke M, Fuller Tova F, Langfelder Peter, DeYoung Joseph, Wokke John H J, Veldink Jan H, van den Berg Leonard H, Ophoff Roel A Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients. BMC genomics. 2009; 10(9): 405.
Cloughesy Tim F, Yoshimoto Koji, Nghiemphu Phioanh, Brown Kevin, Dang Julie, Zhu Shaojun, Hsueh Teli, Chen Yinan, Wang Wei, Youngkin David, Liau Linda, Martin Neil, Becker Don, Bergsneider Marvin, Lai Albert, Green Richard, Oglesby Tom, Koleto Michael, Trent Jeff, Horvath Steve, Mischel Paul S, Mellinghoff Ingo K, Sawyers Charles L Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS medicine. 2008; 5(1): e8.
Langfelder Peter, Zhang Bin, Horvath Steve Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R. Bioinformatics (Oxford, England). 2008; 24(5): 719-20.
Yoshimoto Koji, Dang Julie, Zhu Shaojun, Nathanson David, Huang Tiffany, Dumont Rebecca, Seligson David B, Yong William H, Xiong Zhenggang, Rao Nagesh, Winther Henrik, Chakravarti Arnab, Bigner Darell D, Mellinghoff Ingo K, Horvath Steve, Cavenee Webster K, Cloughesy Timothy F, Mischel Paul S Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008; 14(2): 488-93.
Oldham Michael C, Konopka Genevieve, Iwamoto Kazuya, Langfelder Peter, Kato Tadafumi, Horvath Steve, Geschwind Daniel H Functional organization of the transcriptome in human brain. Nature neuroscience. 2008; 11(11): 1271-82.
Lee Yohan, Scheck Adrienne C, Cloughesy Timothy F, Lai Albert, Dong Jun, Farooqi Haumith K, Liau Linda M, Horvath Steve, Mischel Paul S, Nelson Stanley F Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age. BMC medical genomics. 2008; 1(11): 52.
Horvath Steve, Dong Jun Geometric interpretation of gene coexpression network analysis. PLoS computational biology. 2008; 4(8): e1000117.
Presson Angela P, Sobel Eric M, Papp Jeanette C, Suarez Charlyn J, Whistler Toni, Rajeevan Mangalathu S, Vernon Suzanne D, Horvath Steve Integrated weighted gene co-expression network analysis with an application to chronic fatigue syndrome. BMC systems biology. 2008; 2(1): 95.
Nakano Ichiro, Masterman-Smith Michael, Saigusa Kuniyasu, Paucar Andres A, Horvath Steve, Shoemaker Lorelei, Watanabe Momoko, Negro Alejandra, Bajpai Ruchi, Howes Amy, Lelievre Vincent, Waschek James A, Lazareff Jorge A, Freije William A, Liau Linda M, Gilbertson Richard J, Cloughesy Timothy F, Geschwind Daniel H, Nelson Stanley F, Mischel Paul S, Terskikh Alexey V, Kornblum Harley I Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells. Journal of neuroscience research. 2008; 86(1): 48-60.
Seligson David B, Rajasekaran Sigrid A, Yu Hong, Liu Xueli, Eeva Mervi, Tze Sheila, Ball William, Horvath Steve, deKernion Jean B, Rajasekaran Ayyappan K Na,K-adenosine triphosphatase alpha1-subunit predicts survival of renal clear cell carcinoma. The Journal of urology. 2008; 179(1): 338-45.
Aten Jason E, Fuller Tova F, Lusis Aldons J, Horvath Steve Using genetic markers to orient the edges in quantitative trait networks: the NEO software. BMC systems biology. 2008; 2(8): 34.
Chen Yanqing, Zhu Jun, Lum Pek Yee, Yang Xia, Pinto Shirly, MacNeil Douglas J, Zhang Chunsheng, Lamb John, Edwards Stephen, Sieberts Solveig K, Leonardson Amy, Castellini Lawrence W, Wang Susanna, Champy Marie-France, Zhang Bin, Emilsson Valur, Doss Sudheer, Ghazalpour Anatole, Horvath Steve, Drake Thomas A, Lusis Aldons J, Schadt Eric E Variations in DNA elucidate molecular networks that cause disease. Nature. 2008; 452(7186): 429-35.
Langfelder Peter, Horvath Steve WGCNA: an R package for weighted correlation network analysis. BMC bioinformatics. 2008; 9(1): 559.
Gong Ke Wei, Zhao Wei, Li Ning, Barajas Berenice, Kleinman Michael, Sioutas Constantinos, Horvath Steve, Lusis Aldons J, Nel Andre, Araujo Jesus A Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells. Genome biology. 2007; 8(7): R149.
Abba Martín C, Sun Hongxia, Hawkins Kathleen A, Drake Jeffrey A, Hu Yuhui, Nunez Maria I, Gaddis Sally, Shi Tao, Horvath Steve, Sahin Aysegul, Aldaz C Marcelo Breast cancer molecular signatures as determined by SAGE: correlation with lymph node status. Molecular cancer research : MCR. 2007; 5(9): 881-90.
Langfelder Peter, Horvath Steve Eigengene networks for studying the relationships between co-expression modules. BMC systems biology. 2007; 1(1): 54.
Seligson David B, Hongo Fumiya, Huerta-Yepez Sara, Mizutani Yoichi, Miki Tsuneharu, Yu Hong, Horvath Steve, Chia David, Goodglick Lee, Bonavida Benjamin Expression of X-linked inhibitor of apoptosis protein is a strong predictor of human prostate cancer recurrence. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007; 13(20): 6056-63.
Yip Andy M, Horvath Steve Gene network interconnectedness and the generalized topological overlap measure. BMC bioinformatics. 2007; 8(1-2): 22.
Rahib Lola, MacLennan Nicole K, Horvath Steve, Liao James C, Dipple Katrina M Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling. European journal of human genetics : EJHG. 2007; 15(6): 646-57.
Li Ai, Horvath Steve Network neighborhood analysis with the multi-node topological overlap measure. Bioinformatics (Oxford, England). 2007; 23(2): 222-31.
Carlson Marc R J, Pope Whitney B, Horvath Steve, Braunstein Jerome G, Nghiemphu Phioanh, Tso Cho-Lea, Mellinghoff Ingo, Lai Albert, Liau Linda M, Mischel Paul S, Dong Jun, Nelson Stanley F, Cloughesy Timothy F Relationship between survival and edema in malignant gliomas: role of vascular endothelial growth factor and neuronal pentraxin 2. Clinical cancer research : an official journal of the American Association for Cancer Research. 2007; 13(9): 2592-8.
Eller C Daniel, Regelson Moira, Merriman Barry, Nelson Stan, Horvath Steve, Marahrens York Repetitive sequence environment distinguishes housekeeping genes. Gene. 2007; 390(1-2): 153-65.
Dong Jun, Horvath Steve Understanding network concepts in modules. BMC systems biology. 2007; 1(6-7): 24.
Fuller Tova F, Ghazalpour Anatole, Aten Jason E, Drake Thomas A, Lusis Aldons J, Horvath Steve Weighted gene coexpression network analysis strategies applied to mouse weight. Mammalian genome : official journal of the International Mammalian Genome Society. 2007; 18(6-7): 463-72.
Oldham Michael C, Horvath Steve, Geschwind Daniel H Conservation and evolution of gene coexpression networks in human and chimpanzee brains. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(47): 17973-8.
Mitchell Scherise, Ota Asuka, Foster William, Zhang Bin, Fang Zixing, Patel Shilpa, Nelson Stanley F, Horvath Steve, Wang Yibin Distinct gene expression profiles in adult mouse heart following targeted MAP kinase activation. Physiological genomics. 2006; 25(1): 50-9.
Bocklandt Sven, Horvath Steve, Vilain Eric, Hamer Dean H Extreme skewing of X chromosome inactivation in mothers of homosexual men. Human genetics. 2006; 118(6): 691-4.
Lam John S, Seligson David B, Yu Hong, Li Ai, Eeva Mervi, Pantuck Allan J, Zeng Gang, Horvath Steve, Belldegrun Arie S Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score. BJU international. 2006; 98(2): 445-51.
Carlson Marc R J, Zhang Bin, Fang Zixing, Mischel Paul S, Horvath Steve, Nelson Stanley F Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks. BMC genomics. 2006; 7(1): 40.
Gargalovic Peter S, Imura Minori, Zhang Bin, Gharavi Nima M, Clark Michael J, Pagnon Joanne, Yang Wen-Pin, He Aiqing, Truong Amy, Patel Shilpa, Nelson Stanley F, Horvath Steve, Berliner Judith A, Kirchgessner Todd G, Lusis Aldons J Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(34): 12741-6.
Ghazalpour Anatole, Doss Sudheer, Zhang Bin, Wang Susanna, Plaisier Christopher, Castellanos Ruth, Brozell Alec, Schadt Eric E, Drake Thomas A, Lusis Aldons J, Horvath Steve Integrating genetic and network analysis to characterize genes related to mouse weight. PLoS genetics. 2006; 2(8): e130.
MacLennan Nicole K, Rahib Lola, Shin Cynthia, Fang Zixing, Horvath Steve, Dean Jason, Liao James C, McCabe Edward R B, Dipple Katrina M Targeted disruption of glycerol kinase gene in mice: expression analysis in liver shows alterations in network partners related to glycerol kinase activity. Human molecular genetics. 2006; 15(3): 405-15.
Zhang Bin, Horvath Steve A general framework for weighted gene co-expression network analysis. Statistical applications in genetics and molecular biology. 2005; 4(3): Article17.
Lam John S, Shvarts Oleg, Said Jonathan W, Pantuck Allan J, Seligson David B, Aldridge Michael E, Bui Matthew H T, Liu Xueli, Horvath Steve, Figlin Robert A, Belldegrun Arie S Clinicopathologic and molecular correlations of necrosis in the primary tumor of patients with renal cell carcinoma. Cancer. 2005; 103(12): 2517-25.
Seligson David, Horvath Steve, Huerta-Yepez Sara, Hanna Stephanie, Garban Hermes, Roberts Alice, Shi Tao, Liu Xueli, Chia David, Goodglick Lee, Bonavida Benjamin Expression of transcription factor Yin Yang 1 in prostate cancer. International journal of oncology. 2005; 27(1): 131-41.
Seligson David B, Horvath Steve, Shi Tao, Yu Hong, Tze Sheila, Grunstein Michael, Kurdistani Siavash K Global histone modification patterns predict risk of prostate cancer recurrence. Nature. 2005; 435(7046): 1262-6.
Ouyang Yan, Salstrom Jennifer, Diaz-Perez Silvia, Nahas Shareef, Matsuno Youko, Dawson David, Teitell Michael A, Horvath Steve, Riggs Arthur D, Gatti Richard A, Marahrens York Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome. Biochemical and biophysical research communications. 2005; 337(3): 875-80.
Mellinghoff Ingo K, Wang Maria Y, Vivanco Igor, Haas-Kogan Daphne A, Zhu Shaojun, Dia Ederlyn Q, Lu Kan V, Yoshimoto Koji, Huang Julie H Y, Chute Dennis J, Riggs Bridget L, Horvath Steve, Liau Linda M, Cavenee Webster K, Rao P Nagesh, Beroukhim Rameen, Peck Timothy C, Lee Jeffrey C, Sellers William R, Stokoe David, Prados Michael, Cloughesy Timothy F, Sawyers Charles L, Mischel Paul S Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. The New England journal of medicine. 2005; 353(19): 2012-24.
Lam John S, Yamashiro Joyce, Shintaku I Peter, Vessella Robert L, Jenkins Robert B, Horvath Steve, Said Jonathan W, Reiter Robert E Prostate stem cell antigen is overexpressed in prostate cancer metastases. Clinical cancer research : an official journal of the American Association for Cancer Research. 2005; 11(7): 2591-6.
Zhang Bin, Horvath Steve Ridge regression based hybrid genetic algorithms for multi-locus quantitative trait mapping. International journal of bioinformatics research and applications. 2005; 1(3): 261-72.
Shi Tao, Seligson David, Belldegrun Arie S, Palotie Aarno, Horvath Steve Tumor classification by tissue microarray profiling: random forest clustering applied to renal cell carcinoma. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 2005; 18(4): 547-57.
Kim Hyung L, Seligson David, Liu Xueli, Janzen Nicolette, Bui Matthew H T, Yu Hong, Shi Tao, Belldegrun Arie S, Horvath Steve, Figlin Robert A Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma. The Journal of urology. 2005; 173(5): 1496-501.
Shvarts Oleg, Seligson David, Lam John, Shi Tao, Horvath Steve, Figlin Robert, Belldegrun Arie, Pantuck Allan J p53 is an independent predictor of tumor recurrence and progression after nephrectomy in patients with localized renal cell carcinoma. The Journal of urology. 2005; 173(3): 725-8.
Thomas George V, Horvath Steve, Smith Bradley L, Crosby Katherine, Lebel Lori A, Schrage Matthew, Said Jonathan, De Kernion Jean, Reiter Robert E, Sawyers Charles L Antibody-based profiling of the phosphoinositide 3-kinase pathway in clinical prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2004; 10(24): 8351-6.
Horvath Steve, Xu Xin, Lake Stephen L, Silverman Edwin K, Weiss Scott T, Laird Nan M Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genetic epidemiology. 2004; 26(1): 61-9.
Zhang Bin, Horvath Steve Finding the best ridge regression subset by genetic algorithms: applications to multilocus quantitative trait mapping. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2004; 4(3): 2793-6.
Freije William A, Castro-Vargas F Edmundo, Fang Zixing, Horvath Steve, Cloughesy Timothy, Liau Linda M, Mischel Paul S, Nelson Stanley F Gene expression profiling of gliomas strongly predicts survival. Cancer research. 2004; 64(18): 6503-10.
Flechner Stuart M, Kurian Sunil M, Head Steven R, Sharp Starlette M, Whisenant Thomas C, Zhang Jie, Chismar Jeffrey D, Horvath Steve, Mondala Tony, Gilmartin Timothy, Cook Daniel J, Kay Steven A, Walker John R, Salomon Daniel R Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytes. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2004; 4(9): 1475-89.
Bui Matthew H T, Visapaa Harri, Seligson David, Kim Hyung, Han Ken-Ryu, Huang Yunda, Horvath Steve, Stanbridge Eric J, Palotie Aarno, Figlin Robert A, Belldegrun Arie S Prognostic value of carbonic anhydrase IX and KI67 as predictors of survival for renal clear cell carcinoma. The Journal of urology. 2004; 171(6 Pt 1): 2461-6.
Han Ken-Ryu, Seligson David B, Liu Xueli, Horvath Steve, Shintaku Peter I, Thomas George V, Said Jonathan W, Reiter Robert E Prostate stem cell antigen expression is associated with gleason score, seminal vesicle invasion and capsular invasion in prostate cancer. The Journal of urology. 2004; 171(3): 1117-21.
Liu Xueli, Minin Vladimir, Huang Yunda, Seligson David B, Horvath Steve Statistical methods for analyzing tissue microarray data. Journal of biopharmaceutical statistics. 2004; 14(3): 671-85.
Garraway Isla P, Seligson David, Said Jonathan, Horvath Steve, Reiter Robert E Trefoil factor 3 is overexpressed in human prostate cancer. The Prostate. 2004; 61(3): 209-14.
Kim Hyung L, Seligson David, Liu Xueli, Janzen Nicolette, Bui Matthew H T, Yu Hong, Shi Tao, Figlin Robert A, Horvath Steve, Belldegrun Arie S Using protein expressions to predict survival in clear cell renal carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research. 2004; 10(16): 5464-71.
Kraft Peter, Schadt Eric, Aten Jason, Horvath Steve A family-based test for correlation between gene expression and trait values. American journal of human genetics. 2003; 72(5): 1323-30.
Espineda Cromwell, Seligson David B, James Ball William, Rao JianYu, Palotie Aarno, Horvath Steve, Huang Yunda, Shi Tao, Rajasekaran Ayyappan K Analysis of the Na,K-ATPase alpha- and beta-subunit expression profiles of bladder cancer using tissue microarrays. Cancer. 2003; 97(8): 1859-68.
Choe Gheeyoung, Horvath Steve, Cloughesy Timothy F, Crosby Katherine, Seligson David, Palotie Aarno, Inge Landon, Smith Bradley L, Sawyers Charles L, Mischel Paul S Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo. Cancer research. 2003; 63(11): 2742-6.
Bui Matthew H T, Seligson David, Han Ken-ryu, Pantuck Allan J, Dorey Frederick J, Huang Yunda, Horvath Steve, Leibovich Bradley C, Chopra Shefali, Liao Shu-Yuan, Stanbridge Eric, Lerman Michael I, Palotie Aarno, Figlin Robert A, Belldegrun Arie S Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy. Clinical cancer research : an official journal of the American Association for Cancer Research. 2003; 9(2): 802-11.
Visapää Harri, Bui Matthew, Huang Yunda, Seligson David, Tsai Henry, Pantuck Allan, Figlin Robert, Rao Jian Y u, Belldegrun Arie, Horvath Steve, Palotie Aarno Correlation of Ki-67 and gelsolin expression to clinical outcome in renal clear cell carcinoma. Urology. 2003; 61(4): 845-50.
Shai Ruty, Shi Tao, Kremen Thomas J, Horvath Steve, Liau Linda M, Cloughesy Timothy F, Mischel Paul S, Nelson Stanley F Gene expression profiling identifies molecular subtypes of gliomas. Oncogene. 2003; 22(31): 4918-23.
Allen Elena, Horvath Steve, Tong Frances, Kraft Peter, Spiteri Elizabeth, Riggs Arthur D, Marahrens York High concentrations of long interspersed nuclear element sequence distinguish monoallelically expressed genes. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(17): 9940-5.
Mischel Paul S, Shai Ruty, Shi Tao, Horvath Steve, Lu Kan V, Choe Gheeyoung, Seligson David, Kremen Thomas J, Palotie Aarno, Liau Linda M, Cloughesy Timothy F, Nelson Stanley F Identification of molecular subtypes of glioblastoma by gene expression profiling. Oncogene. 2003; 22(15): 2361-73.
Visapää Harri, Seligson David, Huang Yunda, Rao Jian Yu, Belldegrun Arie, Horvath Steve, Palotie Aarno Ki67, gelsolin and PTEN expression in sarcomatoid renal tumors. Urological research. 2003; 30(6): 387-9.
Freedland Stephen J, Seligson David B, Liu Alvin Y, Pantuck Allan J, Paik Sun H, Horvath Steve, Wieder Jeffrey A, Zisman Amnon, Nguyen David, Tso Cho-Lea, Palotie Aarno V, Belldegrun Arie S Loss of CD10 (neutral endopeptidase) is a frequent and early event in human prostate cancer. The Prostate. 2003; 55(1): 71-80.
Kraft Peter, Bauman Lara, Yuan Jin Ying, Horvath Steve, Horvath Steve Multivariate variance-components analysis of longitudinal blood pressure measurements from the Framingham Heart Study. BMC genetics. 2003; 4 Suppl 1(1): S55.
Haug Karsten, Warnstedt Maike, Alekov Alexi K, Sander Thomas, Ramírez Alfredo, Poser Barbara, Maljevic Snezana, Hebeisen Simon, Kubisch Christian, Rebstock Johannes, Horvath Steve, Hallmann Kerstin, Dullinger Joern S, Rau Birgit, Haverkamp Fritz, Beyenburg Stefan, Schulz Herbert, Janz Dieter, Giese Bernd, Müller-Newen Gerhard, Propping Peter, Elger Christian E, Fahlke Christoph, Lerche Holger, Heils Armin Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies. Nature genetics. 2003; 33(4): 527-32.
Tilgen Nikola, Rebstock Johannes, Horvath Steve, Propping Peter, Elger Christian Erich, Heils Armin Prodynorphin gene promoter polymorphism and temporal lobe epilepsy. Annals of neurology. 2003; 53(2): 280-1; author reply 281-2.
Dewing Phoebe, Shi Tao, Horvath Steve, Vilain Eric Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation. Brain research. Molecular brain research. 2003; 118(1-2): 82-90.
Kraft Peter, Horvath Steve The genetics of gene expression and gene mapping. Trends in biotechnology. 2003; 21(9): 377-8.
Tilgen Nikola, Pfeiffer Heike, Cobilanschi Joana, Rau Birgit, Horvath Steve, Elger Christian E, Propping Peter, Heils Armin Association analysis between the human interleukin 1beta (-511) gene polymorphism and susceptibility to febrile convulsions. Neuroscience letters. 2002; 334(1): 68-70.
Ide Hisamitsu, Seligson David B, Memarzadeh Sanaz, Xin Li, Horvath Steve, Dubey Purnima, Flick Maryann B, Kacinski Barry M, Palotie Aarno, Witte Owen N Expression of colony-stimulating factor 1 receptor during prostate development and prostate cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 2002; 99(22): 14404-9.
Rao JianYu, Seligson David, Visapaa Harri, Horvath Steve, Eeva Mervi, Michel Kia, Pantuck Allan, Belldegrun Arie, Palotie Aarno Tissue microarray analysis of cytoskeletal actin-associated biomarkers gelsolin and E-cadherin in urothelial carcinoma. Cancer. 2002; 95(6): 1247-57.
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