<strong>Related Cores</strong> <br/> <a href="http://www.bioscience.ucla.edu/institution/core-detail?group%5fid=288812">Biopolymer Lab (amino acid analysis, protein sequencing, peptide synthesis, and mass spectrometry)</a> <a href="http://www.bioscience.ucla.edu/institution/core-detail?group%5fid=524217"> Peptide Synthesis Core Facility</a> <br/> <a href="http://www.bioscience.ucla.edu/institution/core-detail?group%5fid=524193"> Surface Plasma Resonance Core</a> <a href="http://www.bioscience.ucla.edu/institution/core-detail?group%5fid=36157"> W. M. Keck Proteomics Center (MIC)</a> <br/> <hr/> <p> <strong> Services Provided by the Core Facility </strong> <br/> The facility provides the UCLA-DOE lab and other members of the UCLA biochemistry community with modern instruments for biomolecular characterization. Instruments are available for biomolecule molecular weight determination, kinetic and thermodynamic analysis of ligand binding, structural characterization, gel documentation and analysis, and radioisotope detection and quantification. The lab manager, Martin Phillips, provides training and assistance in the use of the facility equipment. <br/> <br/> <strong>Facilities and Equipment </strong> <br/> The UCLA-DOE Biochemistry Instrumentation Facility is housed in two adjacent laboratories in Young Hall. The bench tops are wide and deep to easily accommodate large or oddly shaped equipment. Computer network connections are provided throughout the rooms for networking of all the computers controlling the instruments. Please visit the web site above for a current list of equipment housed in the facility.<br/> <br/> <strong>Mode of Operation </strong> <br/> The laboratory provides biochemists and structural molecular biologists at UCLA with easy access to sophisticated instruments. To access these instruments, users simply need to discuss their needs with the facility Manager, Dr. Phillips, who is responsible for training them in the use of the instrument. In some cases, the facility Manager will simply run the experiment for the investigator. For example, use of the analytical ultracentrifuge and analysis of the results requires significant training. In cases where the investigator only requires the molecular weight determination of a few samples, it is a more efficient use of time for the Manager to run the experiment rather than invest in training. In any case, the best course of action will be decided upon in consultation with the investigator. </p> <p> <br/> At present, instrument time is offered on a first come first served basis to anyone at UCLA. In the event that a particular instrument comes under heavy use, it may become necessary to prioritize access. In this case, priority will be assigned based on financial contributions to the facility in general or the instrument in particular. Members of the DOE laboratory, members of Department of Chemistry and Biochemistry and principle investigators on the shared instrumentation grant for a particular instrument will have priority over all others at this time. If access is severely impacted, purchase of additional instruments of the same kind must be considered. A recharge system has been set up to recoup the operating costs. </p>

Young Hall 5062 Young Hall Los Angeles, CA, 90095-1570