Leif Havton, M.D., Ph.D.


Work Titles
UCLA Associate Professor, Neurology Member, UCLA Neurological Rehabilitation and Research Program Member, Brain Research Institute Member, General Neurology Program
Education:
Degrees:
M.D., Umea Universitet Medicinska Fakulteten, 1988
Ph.D.
Fellowship:
1989 - 1991 UCSF Department of Physiology
Internship:
1991 - 1992 St. Mary's Medical Center
Residency:
1995 - 1997 Stanford University Medical Center
1992 - 1995 Stanford University Medical Center
Certifications:
Certifications:
1996 American Board of Psychiatry and Neurology

Contact Information:

Email Address:

lhavton@mednet.ucla.edu


Website:

Web-Profile

Mailing Address:

UCLA Neuro
BOX 957334, 415 NRB
Los Angeles, CA 90095


Publications:

A selected list of publications:

Zai Laila, Ferrari Christina, Dice Carlie, Subbaiah Sathish, Havton Leif A, Coppola Giovanni, Geschwind Daniel, Irwin Nina, Huebner Eric, Strittmatter Stephen M, Benowitz Larry I   Inosine augments the effects of a nogo receptor blocker and of environmental enrichment to restore skilled forelimb use after stroke The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(16): 5977-88.
Ichiyama Ronaldo M, Broman Jonas, Roy Roland R, Zhong Hui, Edgerton V Reggie, Havton Leif A   Locomotor training maintains normal inhibitory influence on both alpha- and gamma-motoneurons after neonatal spinal cord transection The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(1): 26-33.
Victório Sheila C S, Havton Leif A, Oliveira Alexandre L R   Absence of IFNγ expression induces neuronal degeneration in the spinal cord of adult mice Journal of neuroinflammation, 2010; 7(12): 77.
Rosenzweig Ephron S, Courtine Gregoire, Jindrich Devin L, Brock John H, Ferguson Adam R, Strand Sarah C, Nout Yvette S, Roy Roland R, Miller Darren M, Beattie Michael S, Havton Leif A, Bresnahan Jacqueline C, Edgerton V Reggie, Tuszynski Mark H   Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury Nature neuroscience, 2010; 13(12): 1505-10.
Gros Thomas, Sakamoto Jeff S, Blesch Armin, Havton Leif A, Tuszynski Mark H   Regeneration of long-tract axons through sites of spinal cord injury using templated agarose scaffolds Biomaterials, 2010; 31(26): 6719-29.
Brock John H, Rosenzweig Ephron S, Blesch Armin, Moseanko Rod, Havton Leif A, Edgerton V Reggie, Tuszynski Mark H   Local and remote growth factor effects after primate spinal cord injury The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(29): 9728-37.
Havton Leif A, Carlstedt Thomas   Repair and rehabilitation of plexus and root avulsions in animal models and patients Current opinion in neurology, 2009; 22(6): 570-4.
Persson Stefan, Havton Leif A   Retrogradely transported fluorogold accumulates in lysosomes of neurons and is detectable ultrastructurally using post-embedding immuno-gold methods Journal of neuroscience methods, 2009; 184(1): 42-7.
Alto Laura Taylor, Havton Leif A, Conner James M, Hollis Ii Edmund R, Blesch Armin, Tuszynski Mark H   Chemotropic guidance facilitates axonal regeneration and synapse formation after spinal cord injury Nature neuroscience, 2009; 12(9): 1106-13.
Sozmen Elif G, Kolekar Arunima, Havton Leif A, Carmichael S Thomas   A white matter stroke model in the mouse: axonal damage, progenitor responses and MRI correlates Journal of neuroscience methods, 2009; 180(2): 261-72.
Zai Laila, Ferrari Christina, Subbaiah Sathish, Havton Leif A, Coppola Giovanni, Strittmatter Stephen, Irwin Nina, Geschwind Daniel, Benowitz Larry I   Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(25): 8187-97.
Yang Chu-Ya, Song Bingbing, Ao Yan, Nowak Andrew P, Abelowitz Ryan B, Korsak Rose A, Havton Leif A, Deming Timothy J, Sofroniew Michael V   Biocompatibility of amphiphilic diblock copolypeptide hydrogels in the central nervous system Biomaterials, 2009; 30(15): 2881-98.
Kudryashova Elena, Wu Jun, Havton Leif A, Spencer Melissa J   Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component Human molecular genetics, 2009; 18(7): 1353-67.
Rosenzweig Ephron S, Brock John H, Culbertson Maya D, Lu Paul, Moseanko Rod, Edgerton V Reggie, Havton Leif A, Tuszynski Mark H   Extensive spinal decussation and bilateral termination of cervical corticospinal projections in rhesus monkeys The Journal of comparative neurology, 2009; 513(2): 151-63.
Chang Hui-Yi, Havton Leif A   Surgical implantation of avulsed lumbosacral ventral roots promotes restoration of bladder morphology in rats Experimental neurology, 2008; 214(1): 117-24.
Chang Hui-Yi, Havton Leif A   Differential effects of urethane and isoflurane on external urethral sphincter electromyography and cystometry in rats American journal of physiology. Renal physiology, 2008; 295(4): F1248-53.
Chang Hui Yi, Havton Leif A   Re-established micturition reflexes show differential activation patterns after lumbosacral ventral root avulsion injury and repair in rats Experimental neurology, 2008; 212(2): 291-7.
Hoang Thao X, Akhavan Mahnaz, Wu Jun, Havton Leif A   Minocycline protects motor but not autonomic neurons after cauda equina injury Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, 2008; 189(1): 71-7.
Windrem Martha S, Schanz Steven J, Guo Min, Tian Guo-Feng, Washco Vaughn, Stanwood Nancy, Rasband Matthew, Roy Neeta S, Nedergaard Maiken, Havton Leif A, Wang Su, Goldman Steven A   Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse Cell stem cell, 2008; 2(6): 553-65.
Havton Leif A, Hotson John R, Kellerth Jan-Olof   Correlation of median forearm conduction velocity with carpal tunnel syndrome severity Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2007; 118(4): 781-5.
Ichiyama Ronaldo M, Broman Jonas, Edgerton V Reggie, Havton Leif A   Ultrastructural synaptic features differ between alpha- and gamma-motoneurons innervating the tibialis anterior muscle in the rat The Journal of comparative neurology, 2006; 499(2): 306-15.
Hoang Thao X, Pikov Victor, Havton Leif A   Functional reinnervation of the rat lower urinary tract after cauda equina injury and repair The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006; 26(34): 8672-9.
Akhavan Mahnaz, Hoang Thao X, Havton Leif A   Improved detection of fluorogold-labeled neurons in long-term studies Journal of neuroscience methods, 2006; 152(1-2): 156-62.
Ohlsson Marcus, Hoang Thao X, Wu Jun, Havton Leif A   Glial reactions in a rodent cauda equina injury and repair model Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, 2006; 170(1): 52-60.
Hoang Thao X, Havton Leif A   A single re-implanted ventral root exerts neurotropic effects over multiple spinal cord segments in the adult rat Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, 2006; 169(2): 208-17.
Ohlsson Marcus, Havton Leif A   Complement activation after lumbosacral ventral root avulsion injury Neuroscience letters, 2006; 394(3): 179-83.
Hoang Thao X, Havton Leif A   Novel repair strategies to restore bladder function following cauda equina/conus medullaris injuries Progress in brain research, 2006; 152(2): 195-204.
Havton Leif A, Broman Jonas   Systemic administration of cholera toxin B subunit conjugated to horseradish peroxidase in the adult rat labels preganglionic autonomic neurons, motoneurons, and select primary afferents for light and electron microscopic studies Journal of neuroscience methods, 2005; 149(2): 101-9.
Nieto Jaime H, Hoang Thao X, Warner Elizabeth A, Franchini Brett T, Westerlund Ulf, Havton Leif A   Titanium mesh implantation--a method to stabilize the spine and protect the spinal cord following a multilevel laminectomy in the adult rat Journal of neuroscience methods, 2005; 147(1): 1-7.
Warner Elizabeth A, Deyoung Dustin Z, Hoang Thao X, Franchini Brett T, Westerlund Ulf, Havton Leif A   Differential distribution of growth associated protein (GAP-43) in the motor nuclei of the adult rat conus medullaris Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, 2005; 161(4): 527-31.
Lacroix Steve, Havton Leif A, McKay Heather, Yang Hong, Brant Adam, Roberts Jeffrey, Tuszynski Mark H   Bilateral corticospinal projections arise from each motor cortex in the macaque monkey: a quantitative study The Journal of comparative neurology, 2004; 473(2): 147-61.
Dobkin Bruce H, Havton Leif A   Basic advances and new avenues in therapy of spinal cord injury Annual review of medicine, 2004; 55(1): 255-82.
Havton Leif A, Kellerth Jan-Olof   Plasticity of lumbosacral monosynaptic reflexes after a ventral root transection injury in the adult cat Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, 2004; 155(1): 111-4.
Hoang Thao X, Nieto Jaime H, Tillakaratne Niranjala J K, Havton Leif A   Autonomic and motor neuron death is progressive and parallel in a lumbosacral ventral root avulsion model of cauda equina injury The Journal of comparative neurology, 2003; 467(4): 477-86.

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