Robert Strieter, M.D.


Work Titles
UCLA Chief, Interstitial Lung Disease Center Professor, Medicine
Education:
Degrees:
M.D., Michigan State Univ College of Human Medicine, 1983
Fellowship:
1987 - 1989 University of Michigan Health System
Internship:
1983 - 1984 St. Joseph Mercy Hospital
Residency:
1984 - 1986 St. Joseph Mercy Hospital
Certifications:
Certifications:
1989 American Board of Internal Medicine
1988 American Board of Internal Medicine
1986 American Board of Internal Medicine

Contact Information:

Work Phone Number:

(310) 794-1999

Work Address:

14-154 Warren Hall
Campus - 711922
CA


Detailed Biography:

Robert M. Strieter, MD, is Professor of Medicine, Pathology, and Pediatrics, and Chief of the Division of Pulmonary and Critical Care Medicine at the David Geffen School of Medicine at University of California in Los Angeles (UCLA). Dr. Strieter also serves as the Vice Chair of the Department of Medicine for Hospitalist Programs at UCLA. Dr. Strieter received his undergraduate degree at University of Michigan and his medical degree at Michigan State University in East Lansing. After completing his internship and residency in Internal Medicine at St. Joseph Mercy Hospital in Ann Arbor, Dr. Strieter performed his fellowship in Pulmonary and Critical Care at the University of Michigan. Dr. Strieter began his career as Lecturer for the Department of Internal Medicine at University of Michigan and rose rank to full professor with tenure in 1996. Dr. Strieter moved to the David Geffen School of Medicine at UCLA in 2000. Dr. Strieter’s laboratory focuses on four thematic areas that include lung cancer, pulmonary fibrosis, acute lung injury, and lung transplantation. He has focused his research and lectured internationally on cytokine/chemokine biology associated with angiogenesis, inflammation, and immunologically mediated diseases. Dr. Strieter is funded by the NIH and is a Program Director of a NIH/NHLBI Specialized Center of Research in the Pathobiology of Pulmonary Fibrosis; has one R01 in acute lung injury and a second R01 in lung cancer; and is a project leader on the UCLA Lung Cancer SPORE. He currently holds seven patents, with six additional patent applications under review. He is a member of the American Heart Association, American Association of Immunologists, American Association for the Advancement of Science, American Thoracic Society, American Federation for Medical Research, American Society for Clinical Investigation, and the American Society of Investigative Pathology. He is a fellow of both the American College of Chest Physicians and

Publications:

A selected list of publications:

Strieter, RM   Masters of angiogenesis Nature medicine. , 2005; 11(9): 925-7.
Belperio JA Keane MP Burdick MD Gomperts B Mehrad B Saggar R Lynch III JP Ross DJ Strieter RM   Vascular remodeling during the pathogenesis of bronchiolitis obliterans syndrome: the role of CXCR2/CXCR2 ligands, J. Clin. Invest. , 2005; 115: 1150-1162.
Phillips, RJ Mestas, J Gharaee-Kermani, M Burdick, MD Sica, A Belperio, JA Keane, MP Strieter, RM   Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha The Journal of biological chemistry. , 2005; 280(23): 22473-81.
Guha, S. Eibl, G. Kisfalvi, K. Fan, R. S. Burdick, M. Reber, H. Hines, O. J. Strieter, R. Rozengurt, E.   Broad-Spectrum G Protein-Coupled Receptor Antagonist, [D-Arg1,D-Trp5,7,9,Leu11]SP: A Dual Inhibitor of Growth and Angiogenesis in Pancreatic Cancer Cancer Res, 2005; 65(7): 2738-45.
Strieter, RM Belperio, JA Burdick, MD Sharma, S Dubinett, SM Keane, MP   CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer Annals of the New York Academy of Sciences. , 2004; 1028: 351-60.
Ehlert, JE Addison, CA Burdick, MD Kunkel, SL Strieter, RM   Identification and partial characterization of a variant of human CXCR3 generated by posttranscriptional exon skipping Journal of immunology (Baltimore, Md. : 1950) , 2004; 173(10): 6234-40.
Struyf, S Burdick, MD Proost, P Van Damme, J Strieter, RM   Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis Circulation research. , 2004; 95(9): 855-7.
Phillips, RJ Burdick, MD Hong, K Lutz, MA Murray, LA Xue, YY Belperio, JA Keane, MP Strieter, RM   Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis The Journal of clinical investigation. , 2004; 114(3): 438-46.
Addison, CL Belperio, JA Burdick, MD Strieter, RM   Overexpression of the duffy antigen receptor for chemokines (DARC) by NSCLC tumor cells results in increased tumor necrosis BMC cancer [electronic resource]. , 2004; 4(1): 28.
Strieter, R. M. Belperio, J. A. Phillips, R. J. Keane, M. P.   CXC chemokines in angiogenesis of cancer Semin Cancer Biol, 2004; 14(3): 195-200.
Strieter, RM Belperio, JA Phillips, RJ Keane, MP   Chemokines: angiogenesis and metastases in lung cancer Novartis Foundation symposium. , 2004; 256: 173-84; discussion 184-8, 259-69.
Belperio, JA Phillips, RJ Burdick, MD Lutz, M Keane, M Strieter, R   The SDF-1/CXCL 12/CXCR4 biological axis in non-small cell lung cancer metastases Chest. , 2004; 125(5 Suppl): 156S.
Keane, MP Burdick, MD Xue, YY Lutz, M Belperio, JA Strieter, RM   The chemokine receptor, CXCR2, mediates the tumorigenic effects of ELR+ CXC chemokines Chest. , 2004; 125(5 Suppl): 133S.
Pold, M. Zhu, L. X. Sharma, S. Burdick, M. D. Lin, Y. Lee, P. P. Pold, A. Luo, J. Krysan, K. Dohadwala, M. Mao, J. T. Batra, R. K. Strieter, R. M. Dubinett, S. M.   Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer Cancer Res, 2004; 64(5): 1853-60.
Keane, MP Belperio, JA Xue, YY Burdick, MD Strieter, RM   Depletion of CXCR2 inhibits tumor growth and angiogenesis in a murine model of lung cancer Journal of immunology (Baltimore, Md. : 1950) , 2004; 172(5): 2853-60.
Strieter, RM Burdick, MD Belperio, JA Keane, MP   Measurement of chemokines at the protein level in tissue Methods in molecular medicine. , 2003; 78: 377-88.
Phillips, RJ Burdick, MD Lutz, M Belperio, JA Keane, MP Strieter, RM   The stromal derived factor-1/CXCL12-CXC chemokine receptor 4 biological axis in non-small cell lung cancer metastases American journal of respiratory and critical care medicine. , 2003; 167(12): 1676-86.
Strieter, RM   Mastering innate immunity Nature medicine. , 2003; 9(5): 512-3.

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