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Shaping the Future

Kenneth Subotnik, Ph.D.

Contact Information:

Work Phone Number:

(310) 825-0334

Email Address:

ksubotnik@mednet.ucla.edu

Website:

  

Laboratory:

     Aftercare Research Program


Research Psychologist, Psychiatry and Biobehavioral Sciences

Adjunct Professor, Resnick Neuropsychiatric Hospital

Semel Institute for Neuroscience and Human Behavior


A Short Biography:

Vulnerability factors for schizophrenia, antipsychotic medication adherence, insight.

Awards and Honors:

UCLA Neuropsychiatric Hospital

Detailed Biography:

Kenneth Subotnik, Ph.D. is a Research Psychologist and Adjunct Professor of the Department of Psychiatry & Biobehavioral Sciences. He is the Associate Director of the Aftercare Research Program, and co-Director of the Chronic Schizophrenia Recruitment and Assessment Core. He received his Ph.D. from the UCLA Department of Psychology in 1990. His areas of special research interest include, the examination of psychometric vulnerability indicators in schizophrenia patients and their family members, with a focus on measures such as

  • the examination of formal thought disorder and its relationship to neurocognitive and neuroanatomical abnormalities;
  • the early course of positive and negative schizophrenia symptoms and their clinical correlates;
  • the examination of psychological factors affecting medication adherence, such as insight and attitudes toward antipsychotic medication.

Publications:

McCleery A, Ventura J, Kern R S, Subotnik K L, Gretchen-Doorly D, Green M F, Hellemann G S, Nuechterlein K H   Cognitive functioning in first-episode schizophrenia: MATRICS Consensus Cognitive Battery (MCCB) Profile of Impairment Schizophrenia research, 2014; 157(1-3): 33-9.
Ventura Joseph, Subotnik Kenneth L, Ered Arielle, Gretchen-Doorly Denise, Hellemann Gerhard S, Vaskinn Anja, Nuechterlein Keith H   The Relationship of Attitudinal Beliefs to Negative Symptoms, Neurocognition, and Daily Functioning in Recent-Onset Schizophrenia Schizophrenia bulletin, 2014; .
Nuechterlein Keith H, Ventura Joseph, Subotnik Kenneth L, Bartzokis George   The early longitudinal course of cognitive deficits in schizophrenia The Journal of clinical psychiatry, 2014; 75 Suppl 2: 25-9.
Bartzokis George, Lu Po H, Raven Erika P, Amar Chetan P, Detore Nicole R, Couvrette Alexander J, Mintz Jim, Ventura Joseph, Casaus Laurie R, Luo John S, Subotnik Kenneth L, Nuechterlein Keith H   Impact on intracortical myelination trajectory of long acting injection versus oral risperidone in first-episode schizophrenia Schizophrenia research, 2012; 140(1-3): 122-8.
Moran Zachary D, Williams Terrance J, Bachman Peter, Nuechterlein Keith H, Subotnik Kenneth L, Yee Cindy M   Spectral decomposition of P50 suppression in schizophrenia during concurrent visual processing Schizophrenia research, 2012; 140(1-3): 237-42.
Subotnik Kenneth L, Schell Anne M, Chilingar Mark S, Dawson Michael E, Ventura Joseph, Kelly Kimberle A, Hellemann Gerhard S, Nuechterlein Keith H   The interaction of electrodermal activity and expressed emotion in predicting symptoms in recent-onset schizophrenia Psychophysiology, 2012; .
Gretchen-Doorly Denise, Kite Robin E, Subotnik Kenneth L, Detore Nicole R, Ventura Joseph, Kurtz Andrew S, Nuechterlein Keith H   Cardiorespiratory endurance, muscular flexibility and strength in first-episode schizophrenia patients: use of a standardized fitness assessment Early intervention in psychiatry, 2012; 6(2): 185-90.
Nuechterlein Keith H, Subotnik Kenneth L, Ventura Joseph, Green Michael F, Gretchen-Doorly Denise, Asarnow Robert F   The puzzle of schizophrenia: tracking the core role of cognitive deficits Development and psychopathology, 2012; 24(2): 529-36.
Bartzokis George, Lu Po H, Amar Chetan P, Raven Erika P, Detore Nicole R, Altshuler Lori L, Mintz Jim, Ventura Joseph, Casaus Laurie R, Luo John S, Subotnik Kenneth L, Nuechterlein Keith H   Long acting injection versus oral risperidone in first-episode schizophrenia: differential impact on white matter myelination trajectory Schizophrenia research, 2011; 132(1): 35-41.
Nuechterlein Keith H, Subotnik Kenneth L, Green Michael F, Ventura Joseph, Asarnow Robert F, Gitlin Michael J, Yee Cindy M, Gretchen-Doorly Denise, Mintz Jim   Neurocognitive predictors of work outcome in recent-onset schizophrenia Schizophrenia bulletin, 2011; 37 Suppl 2(1): S33-40.
Ventura Joseph, Subotnik Kenneth L, Guzik Lisa H, Hellemann Gerhard S, Gitlin Michael J, Wood Rachel C, Nuechterlein Keith H   Remission and recovery during the first outpatient year of the early course of schizophrenia Schizophrenia research, 2011; .
Williams Terrance J, Nuechterlein Keith H, Subotnik Kenneth L, Yee Cindy M   Distinct neural generators of sensory gating in schizophrenia Psychophysiology, 2011; 48(4): 470-8.
Gretchen-Doorly Denise, Detore Nicole R, Ventura Joseph, Hellemann Gerhard, Subotnik Kenneth L, Nuechterlein Keith H   Relationships between perceptions of the family environment and of negative life events in recent-onset schizophrenia patients Schizophrenia research, 2011; 127(1-3): 266-7.
Subotnik Kenneth L, Nuechterlein Keith H, Ventura Joseph, Gitlin Michael J, Marder Stephen, Mintz Jim, Hellemann Gerhard S, Thornton Leslie A, Singh Indira R   Risperidone nonadherence and return of positive symptoms in the early course of schizophrenia The American journal of psychiatry, 2011; 168(3): 286-92.
Horan William P, Green Michael F, Degroot Michael, Fiske Alan, Hellemann Gerhard, Kee Kimmy, Kern Robert S, Lee Junghee, Sergi Mark J, Subotnik Kenneth L, Sugar Catherine A, Ventura Joseph, Nuechterlein Keith H   Social Cognition in Schizophrenia, Part 2: 12-Month Stability and Prediction of Functional Outcome in First-Episode Patients Schizophrenia bulletin, 2011; 127(1-3): .
Green Michael F, Bearden Carrie E, Cannon Tyrone D, Fiske Alan P, Hellemann Gerhard S, Horan William P, Kee Kimmy, Kern Robert S, Lee Junghee, Sergi Mark J, Subotnik Kenneth L, Sugar Catherine A, Ventura Joseph, Yee Cindy M, Nuechterlein Keith H   Social Cognition in Schizophrenia, Part 1: Performance Across Phase of Illness Schizophrenia bulletin, 2011; 168(3): .
Yang Yaling, Nuechterlein Keith H, Phillips Owen, Hamilton Liberty S, Subotnik Kenneth L, Asarnow Robert F, Toga Arthur W, Narr Katherine L   The contributions of disease and genetic factors towards regional cortical thinning in schizophrenia: the UCLA family study Schizophrenia research, 2010; 123(2-3): 116-25.
Dawson Michael E, Schell Anne M, Rissling Anthony, Ventura Joseph, Subotnik Kenneth L, Nuechterlein Keith H   Psychophysiological prodromal signs of schizophrenic relapse: a pilot study Schizophrenia research, 2010; 123(1): 64-7.
Phillips Owen R, Clark Kristi A, Woods Roger P, Subotnik Kenneth L, Asarnow Robert F, Nuechterlein Keith H, Toga Arthur W, Narr Katherine L   Topographical relationships between arcuate fasciculus connectivity and cortical thickness Human brain mapping, 2010; 123(1): .
Fogelson D L, Asarnow R A, Sugar C A, Subotnik K L, Jacobson K C, Neale M C, Kendler K S, Kuppinger H, Nuechterlein K H   Avoidant personality disorder symptoms in first-degree relatives of schizophrenia patients predict performance on neurocognitive measures: the UCLA family study Schizophrenia research, 2010; 120(1-3): 113-20.
Yee Cindy M, Williams Terrance J, White Patricia M, Nuechterlein Keith H, Ames Donna, Subotnik Kenneth L   Attentional modulation of the P50 suppression deficit in recent-onset and chronic schizophrenia Journal of abnormal psychology, 2010; 119(1): 31-9.
Yee Cindy M, Mathis Kristopher Ian, Sun Jane C, Sholty Gretchen L, Lang Peter J, Bachman Peter, Williams Terrance J, Bearden Carrie E, Cannon Tyrone D, Green Michael F, Subotnik Kenneth L, Ventura Joseph, Nuechterlein Keith H   Integrity of emotional and motivational states during the prodromal, first-episode, and chronic phases of schizophrenia Journal of abnormal psychology, 2010; 119(1): 71-82.
Gretchen-Doorly Denise, Subotnik Kenneth L, Kite Robin E, Alarcon Evelyn, Nuechterlein Keith H   Development and evaluation of a health promotion group for individuals with severe psychiatric disabilities Psychiatric rehabilitation journal, 2009; 33(1): 56-9.
Bartzokis George, Lu Po H, Stewart Stephanie B, Oluwadara Bolanle, Lucas Andrew J, Pantages Joanna, Pratt Erika, Sherin Jonathan E, Altshuler Lori L, Mintz Jim, Gitlin Michael J, Subotnik Kenneth L, Nuechterlein Keith H   In vivo evidence of differential impact of typical and atypical antipsychotics on intracortical myelin in adults with schizophrenia Schizophrenia research, 2009; 113(2-3): 322-31.
Kern R S, Green M F, Fiske A P, Kee K S, Lee J, Sergi M J, Horan W P, Subotnik K L, Sugar C A, Nuechterlein K H   Theory of mind deficits for processing counterfactual information in persons with chronic schizophrenia Psychological medicine, 2009; 39(4): 645-54.
Sergi Mark J, Fiske Alan P, Horan William P, Kern Robert S, Kee Kimmy S, Subotnik Kenneth L, Nuechterlein Keith H, Green Michael F   Development of a measure of relationship perception in schizophrenia Psychiatry research, 2009; 166(1): 54-62.
Kee, Horan, Salovey, Kern, Sergi, Fiske, Lee, Subotnik, Nuechterlein, Sugar, Green   Emotional intelligence in schizophrenia Schizophrenia research, 2008; .
Nuechterlein Keith H, Subotnik Kenneth L, Turner Luana R, Ventura Joseph, Becker Deborah R, Drake Robert E   Individual placement and support for individuals with recent-onset schizophrenia: integrating supported education and supported employment Psychiatric rehabilitation journal, 2008; 31(4): 340-9.
Lee Junghee, Nuechterlein Keith H, Subotnik Kenneth L, Sugar Catherine A, Ventura Joseph, Gretchen-Doorly Denise, Kelly Kimberly, Green Michael F   Stability of visual masking performance in recent-onset schizophrenia: an 18-month longitudinal study Schizophrenia research, 2008; 103(1-3): 266-74.
van Erp Theo G M, Lesh Tyler A, Knowlton Barbara J, Bearden Carrie E, Hardt Molly, Karlsgodt Katherine H, Shirinyan David, Rao Vikas, Green Michael F, Subotnik Kenneth L, Nuechterlein Keith, Cannon Tyrone D   Remember and know judgments during recognition in chronic schizophrenia Schizophrenia research, 2008; 100(1-3): 181-90.
Horan William P, Reise Steven P, Subotnik Kenneth L, Ventura Joseph, Nuechterlein Keith H   The validity of Psychosis Proneness Scales as vulnerability indicators in recent-onset schizophrenia patients Schizophrenia research, 2008; 100(1-3): 224-36.
Fogelson D L, Nuechterlein K H, Asarnow R A, Payne D L, Subotnik K L, Jacobson K C, Neale M C, Kendler K S   Avoidant personality disorder is a separable schizophrenia-spectrum personality disorder even when controlling for the presence of paranoid and schizotypal personality disorders The UCLA family study Schizophrenia research, 2007; 91(1-3): 192-9.
Subotnik Kenneth L, Nuechterlein Keith H, Green Michael F, Horan William P, Nienow Tasha M, Ventura Joseph, Nguyen Annie T   Neurocognitive and social cognitive correlates of formal thought disorder in schizophrenia patients Schizophrenia research, 2006; 85(1-3): 84-95.
Horan William P, Subotnik Kenneth L, Snyder Karen S, Nuechterlein Keith H   Do recent-onset schizophrenia patients experience a "social network crisis"? Psychiatry, 2006; 69(2): 115-29.
Nuechterlein Keith H, Pashler Harold E, Subotnik Kenneth L   Translating basic attentional paradigms to schizophrenia research: reconsidering the nature of the deficits Development and psychopathology, 2006; 18(3): 831-51.
Schell Anne M, Dawson Michael E, Rissling Anthony, Ventura Joseph, Subotnik Kenneth L, Gitlin Michael J, Nuechterlein Keith H   Electrodermal predictors of functional outcome and negative symptoms in schizophrenia Psychophysiology, 2005; 42(4): 483-92.
Horan William P, Subotnik Kenneth L, Reise Steven P, Ventura Joseph, Nuechterlein Keith H   Stability and clinical correlates of personality characteristics in recent-onset schizophrenia Psychological medicine, 2005; 35(7): 995-1005.
Subotnik Kenneth L, Nuechterlein Keith H, Irzhevsky Victoria, Kitchen Christina M, Woo Stephanie M, Mintz Jim   Is unawareness of psychotic disorder a neurocognitive or psychological defensiveness problem? Schizophrenia research, 2005; 75(2-3): 147-57.
Horan William P, Ventura Joseph, Nuechterlein Keith H, Subotnik Kenneth L, Hwang Sun S, Mintz Jim   Stressful life events in recent-onset schizophrenia: reduced frequencies and altered subjective appraisals Schizophrenia research, 2005; 75(2-3): 363-74.
Subotnik Kenneth L, Asarnow Robert F, Nuechterlein Keith H, Fogelson David L, Thorpe Tamsen I, Payne Diana L, Giannini Carol A, Kuppinger Heidi E, Torquato Richard D, Mintz Jim, Hwang Sun S, Gottesman Irving I   MMPI vulnerability indicators for schizophrenia and attention deficit disorder: UCLA family study of biological parents of offspring with childhood-onset schizophrenia or ADHD Behavior genetics, 2005; 35(2): 159-75.
Ventura Joseph, Nuechterlein Keith H, Subotnik Kenneth L, Green Michael F, Gitlin Michael J   Self-efficacy and neurocognition may be related to coping responses in recent-onset schizophrenia Schizophrenia research, 2004; 69(2-3): 343-52.
Ventura Joseph, Nuechterlein Keith H, Green Michael F, Horan William P, Subotnik Kenneth L, Mintz Jim   The timing of negative symptom exacerbations in relationship to positive symptom exacerbations in the early course of schizophrenia Schizophrenia research, 2004; 69(2-3): 333-42.
Fogelson David L, Nuechterlein Keith H, Asarnow Robert F, Payne Diana L, Subotnik Kenneth L   Validity of the family history method for diagnosing schizophrenia, schizophrenia-related psychoses, and schizophrenia-spectrum personality disorders in first-degree relatives of schizophrenia probands Schizophrenia research, 2004; 68(2-3): 309-17.
Subotnik Kenneth L, Bartzokis George, Green Michael F, Nuechterlein Keith H   Neuroanatomical correlates of formal thought disorder in schizophrenia Cognitive neuropsychiatry, 2003; 8(2): 81-8.
Asarnow Robert F, Nuechterlein Keith H, Subotnik Kenneth L, Fogelson David L, Torquato Richard D, Payne Diana L, Asamen Joy, Mintz Jim, Guthrie Donald   Neurocognitive impairments in nonpsychotic parents of children with schizophrenia and attention-deficit/hyperactivity disorder: the University of California, Los Angeles Family Study Archives of general psychiatry, 2002; 59(11): 1053-60.
Subotnik Kenneth L, Goldstein Michael J, Nuechterlein Keith H, Woo Stephanie M, Mintz Jim   Are communication deviance and expressed emotion related to family history of psychiatric disorders in schizophrenia? Schizophrenia bulletin, 2002; 28(4): 719-29.
Asarnow Robert F, Nuechterlein Keith H, Asamen Joy, Fogelson David, Subotnik Kenneth L, Zaucha Kenneth, Guthrie Donald   Neurocognitive functioning and schizophrenia spectrum disorders can be independent expressions of familial liability for schizophrenia in community control children: the UCLA family study Schizophrenia research, 2002; 54(1-2): 111-20.
Nuechterlein Keith H, Asarnow Robert F, Subotnik Kenneth L, Fogelson David L, Payne Diana L, Kendler Kenneth S, Neale Michael C, Jacobson Kristen C, Mintz Jim   The structure of schizotypy: relationships between neurocognitive and personality disorder features in relatives of schizophrenic patients in the UCLA Family Study Schizophrenia research, 2002; 54(1-2): 121-30.
Schell Anne M, Dawson Michael E, Nuechterlein Keith H, Subotnik Kenneth L, Ventura Joseph   The temporal stability of electrodermal variables over a one-year period in patients with recent-onset schizophrenia and in normal subjects Psychophysiology, 2002; 39(2): 124-32.
Gitlin M, Nuechterlein K, Subotnik K L, Ventura J, Mintz J, Fogelson D L, Bartzokis G, Aravagiri M   Clinical outcome following neuroleptic discontinuation in patients with remitted recent-onset schizophrenia The American journal of psychiatry, 2001; 158(11): 1835-42.
Asarnow R F, Nuechterlein K H, Fogelson D, Subotnik K L, Payne D A, Russell A T, Asamen J, Kuppinger H, Kendler K S   Schizophrenia and schizophrenia-spectrum personality disorders in the first-degree relatives of children with schizophrenia: the UCLA family study Archives of general psychiatry, 2001; 58(6): 581-8.
Rosenfarb I S, Nuechterlein K H, Goldstein M J, Subotnik K L   Neurocognitive vulnerability, interpersonal criticism, and the emergence of unusual thinking by schizophrenic patients during family transactions Archives of general psychiatry, 2000; 57(12): 1174-9.
Ventura J, Nuechterlein K H, Subotnik K L, Gutkind D, Gilbert E A   Symptom dimensions in recent-onset schizophrenia and mania: a principal components analysis of the 24-item Brief Psychiatric Rating Scale Psychiatry research, 2000; 97(2-3): 129-35.
Gitlin M J, Nuechterlein K H, Mintz J, Fogelson D, Bartzokis G, Ventura J, Subotnik K, Aravagiri M   Fluphenazine levels during maintenance treatment of recent-onset schizophrenia: relation to side effects, psychosocial function and depression Psychopharmacology, 2000; 148(4): 350-4.
Subotnik K L, Nuechterlein K H, Ventura J   MMPI discriminators of deficit vs. non-deficit recent-onset schizophrenia patients Psychiatry research, 2000; 93(2): 111-23.
Ventura J, Nuechterlein K H, Subotnik K L, Hardesty J P, Mintz J   Life events can trigger depressive exacerbation in the early course of schizophrenia Journal of abnormal psychology, 2000; 109(1): 139-44.
Fogelson J, Nuechterlein J, Asarnow J, Payne J, Subotnik J, Giannini J   The factor structure of schizophrenia spectrum personality disorders: signs and symptoms in relatives of psychotic patients from the UCLA family members study Psychiatry research, 1999; 87(2-3): 137-46.
Subotnik K L, Nuechterlein K H, Green M F   Trait versus state aspects of the MMPI during the early course of schizophrenia Journal of psychiatric research, 1999; 33(3): 275-84.
Subotnik K L, Nuechterlein K H, Ventura J, Green M F, Hwang S S   Prediction of the deficit syndrome from initial deficit symptoms in the early course of schizophrenia Psychiatry research, 1998; 80(1): 53-9.
Subotnik K L, Nuechterlein K H, Asarnow R F, Fogelson D L, Goldstein M J, Talovic S A   Depressive symptoms in the early course of schizophrenia: relationship to familial psychiatric illness The American journal of psychiatry, 1997; 154(11): 1551-6.
Nuechterlein K H, Gitlin M J, Subotnik K L   The early course of schizophrenia and long-term maintenance neuroleptic therapy Archives of general psychiatry, 1995; 52(3): 203-5.
Nuechterlein K H, Dawson M E, Ventura J, Gitlin M, Subotnik K L, Snyder K S, Mintz J, Bartzokis G   The vulnerability/stress model of schizophrenic relapse: a longitudinal study Acta psychiatrica Scandinavica. Supplementum, 1994; 382(3): 58-64.
Goldstein M J, Talovic S A, Nuechterlein K H, Fogelson D L, Subotnik K L, Asarnow R F   Family interaction versus individual psychopathology. Do they indicate the same processes in the families of schizophrenics? The British journal of psychiatry. Supplement, 1992; 382(18): 97-102.
Fogelson D L, Nuechterlein K H, Asarnow R F, Subotnik K L, Talovic S A   Interrater reliability of the Structured Clinical Interview for DSM-III-R, Axis II: schizophrenia spectrum and affective spectrum disorders Psychiatry research, 1991; 39(1): 55-63.
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