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Marian Sigman, Ph.D.

Contact Information:

Work Phone Number:

310-825-0180

Mailing Address:

760 Westwood Plaza Semel Institute
Los Angeles, CA 90095
UNITED STATES

Email Address:

msigman@ucla.edu

Work Email Address:

msigman@ucla.edu

Professor, Psychiatry and Biobehavioral Sciences

Professor in Residence, Center for Autism Research and Treatment (CART)

Member, Child and Adolescent Psychiatry

(Retired)

Awards and Honors:

UCLA Neuropsychiatric Hospital

Detailed Biography:

Professor Emeritus: Clinical Psychology and Psychiatry; David Geffen School of Medicine at UCLA

Marian Sigman, Ph.D. is the former Co-Founder and Co-Director of the UCLA Center for Autism Research and Treatment (CART), one of the eight NIH-funded STAART centers (2003-2008), and now one of six NIH-funded ACE Centers, in the nation.  She also was Director of the UCLA Collaborative Program of Excellence in Autism (CPEA) also funded by NIH.  The focus of Dr. Sigman's research has been to determine the biological and environmental contributors to social communicative deficits and skills in autism.  Dr. Sigman, a developmental and child clinical psychologist and UCLA Professor of Psychiatry and Biobehavioral Sciences and Psychology, is an internationally acclaimed scholar and teacher.  She obtained her Ph.D. in Psychology from Boston University and was a postdoctoral fellow at UCLA before joining the UCLA faculty in 1977.  With an accomplished career spanning over 30 years, Dr. Sigman retired in 2010 and left her mark on the field with a rich history of significant scientific contributions.  Her well-respected research program has made a major impact on understanding autism, anxiety, developmental disabilities, effects of nutrition and low birth weight on cognitive development, and interventions to support children and families at risk.  Her most recent research program focuses on early identification and effective interventions with families with children with autism and autism spectrum disorders.

Dr. Sigman is widely published in her field with more than 155 peer-reviewed research reports and over 55 book chapters.  She also is co-author of the widely-praised book, Children with Autism: A Developmental Perspective (1977).  She has had a long standing record of success in obtaining extramural funding for her research.  In addition to many individual grants, she has been awarded the following highly competitive National Institutes of Health (NIH) program project and center grants:  Collaborative Program of Excellence in Autism (CPEA; 1997-2007), Studies to Advance Autism Research and Treatment (STAART; 2003-2008), and Autism Center for Excellence (ACE; 2007-2012).  Notable milestones in autism research include Dr. Sigman and colleagues' work which 1) demonstrated fundamental deficits in joint attention and presented the concept of core cognitive deficits in autism; 2) initiated novel intervention approaches based on basic research in child development; and 3) studied infant siblings of autistic children (i.e., high risk) to identify predictors of autism and prognostic information.

Throughout her career, Dr. Sigman has provided outstanding and distinguished teaching and service to the University and the academic community.  She has supervised the research of over 12 postdoctoral fellows and the doctoral training of more than 30 graduate students in clinical and developmental psychology.  Her students and peers alike provide exceptionally positive evaluations of Dr. Sigman's role as a unique and highly esteemed teacher, role model and colleague.  She was named outstanding research mentor in the UCLA Department of Psychiatry in 2000.  For 18 years, she served as training director for the NIMH funded UCLA Research Training Program Childhood Psychopathology.  She has served on Academic Senate committees and numerous local departmental and Medical School committees.  She also has provided significant service outside of UCLA.  She was the first President of the International Society for Autism Research, Chair of the Advisory Committee of the National Childcare Study, and founding President of the International Society for Infant Studies.  She also served for five years as Associate Editor of Child Development, the leading journal in the field of developmental psychology.  In February 2009, CART hosted an all-day research symposium at UCLA in honor of Dr. Sigman's long and productive scientific career.  In May 2009, she received the Lifetime Achievement Award from the International Meeting for Autism research (IMFAR).

Publications:

Gotham Katherine, Risi Susan, Dawson Geraldine, Tager-Flusberg Helen, Joseph Robert, Carter Alice, Hepburn Susan, McMahon William, Rodier Patricia, Hyman Susan L, Sigman Marian, Rogers Sally, Landa Rebecca, Spence M Anne, Osann Kathryn, Flodman Pamela, Volkmar Fred, Hollander Eric, Buxbaum Joseph, Pickles Andrew, Lord Catherine   A replication of the Autism Diagnostic Observation Schedule (ADOS) revised algorithms Journal of the American Academy of Child and Adolescent Psychiatry, 2008; 47(6): 642-51.
Wang Nicholas J, Parokonny Alexander S, Thatcher Karen N, Driscoll Jennette, Malone Barbara M, Dorrani Naghmeh, Sigman Marian, LaSalle Janine M, Schanen N Carolyn   Multiple forms of atypical rearrangements generating supernumerary derivative chromosome 15 BMC genetics, 2008; 9(6): 2.
Nishimura Yuhei, Martin Christa L, Vazquez-Lopez Araceli, Spence Sarah J, Alvarez-Retuerto Ana Isabel, Sigman Marian, Steindler Corinna, Pellegrini Sandra, Schanen N Carolyn, Warren Stephen T, Geschwind Daniel H   Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways Human molecular genetics, 2007; 16(14): 1682-98.
Wang A Ting, Lee Susan S, Sigman Marian, Dapretto Mirella   Reading affect in the face and voice: neural correlates of interpreting communicative intent in children and adolescents with autism spectrum disorders Archives of general psychiatry, 2007; 64(6): 698-708.
Nadig Aparna S, Ozonoff Sally, Young Gregory S, Rozga Agata, Sigman Marian, Rogers Sally J   A prospective study of response to name in infants at risk for autism Archives of pediatrics & adolescent medicine, 2007; 161(4): 378-83.
Zwaigenbaum Lonnie, Thurm Audrey, Stone Wendy, Baranek Grace, Bryson Susan, Iverson Jana, Kau Alice, Klin Ami, Lord Cathy, Landa Rebecca, Rogers Sally, Sigman Marian   Studying the emergence of autism spectrum disorders in high-risk infants: methodological and practical issues Journal of autism and developmental disorders, 2007; 37(3): 466-80.
Yirmiya Nurit, Gamliel Ifat, Shaked Michal, Sigman Marian   Cognitive and verbal abilities of 24- to 36-month-old siblings of children with autism Journal of autism and developmental disorders, 2007; 37(2): 218-29.
Gamliel Ifat, Yirmiya Nurit, Sigman Marian   The development of young siblings of children with autism from 4 to 54 months Journal of autism and developmental disorders, 2007; 37(1): 171-83.
Lainhart Janet E, Bigler Erin D, Bocian Maureen, Coon Hilary, Dinh Elena, Dawson Geraldine, Deutsch Curtis K, Dunn Michelle, Estes Annette, Tager-Flusberg Helen, Folstein Susan, Hepburn Susan, Hyman Susan, McMahon William, Minshew Nancy, Munson Jeff, Osann Kathy, Ozonoff Sally, Rodier Patricia, Rogers Sally, Sigman Marian, Spence M Anne, Stodgell Christopher J, Volkmar Fred   Head circumference and height in autism: a study by the Collaborative Program of Excellence in Autism American journal of medical genetics. Part A, 2006; 140(21): 2257-74.
Rotheram-Borus Mary Jane, Lester Patricia, Song Juwon, Lin Ying-Ying, Leonard Noelle R, Beckwith Leila, Ward Mary J, Sigman Marian, Lord Lynwood   Intergenerational benefits of family-based HIV interventions Journal of consulting and clinical psychology, 2006; 74(3): 622-7.
Yirmiya Nurit, Gamliel Ifat, Pilowsky Tammy, Feldman Ruth, Baron-Cohen Simon, Sigman Marian   The development of siblings of children with autism at 4 and 14 months: social engagement, communication, and cognition Journal of child psychology and psychiatry, and allied disciplines, 2006; 47(5): 511-23.
Molloy Cynthia A, Morrow Ardythe L, Meinzen-Derr Jareen, Dawson Geraldine, Bernier Raphael, Dunn Michelle, Hyman Susan L, McMahon William M, Goudie-Nice Julie, Hepburn Susan, Minshew Nancy, Rogers Sally, Sigman Marian, Spence M Anne, Tager-Flusberg Helen, Volkmar Fred R, Lord Catherine   Familial autoimmune thyroid disease as a risk factor for regression in children with Autism Spectrum Disorder: a CPEA Study Journal of autism and developmental disorders, 2006; 36(3): 317-24.
Richler Marian, Luyster Marian, Risi Marian, Hsu Marian, Dawson Marian, Bernier Marian, Dunn Marian, Hepburn Marian, Hyman Marian, McMahon Marian, Goudie-Nice Marian, Minshew Marian, Rogers Marian, Sigman Marian, Spence Marian, Goldberg Marian, Tager-Flusberg Marian, Volkmar Marian, Lord Marian   Is There a 'Regressive Phenotype' of Autism Spectrum Disorder Associated with the Measles-Mumps-Rubella Vaccine? A CPEA Study Journal of autism and developmental disorders, 2006; 47(5): .
Richler Jennifer, Luyster Rhiannon, Risi Susan, Hsu Wan-Ling, Dawson Geraldine, Bernier Raphael, Dunn Michelle, Hepburn Susan, Hyman Susan L, McMahon William M, Goudie-Nice Julie, Minshew Nancy, Rogers Sally, Sigman Marian, Spence M Anne, Goldberg Wendy A, Tager-Flusberg Helen, Volkmar Fred R, Lord Catherine   Is there a 'regressive phenotype' of Autism Spectrum Disorder associated with the measles-mumps-rubella vaccine? A CPEA Study Journal of autism and developmental disorders, 2006; 36(3): 299-316.
Wang A Ting, Lee Susan S, Sigman Marian, Dapretto Mirella   Neural basis of irony comprehension in children with autism: the role of prosody and context Brain : a journal of neurology, 2006; 129(Pt 4): 932-43.
Sigman Marian, Spence Sarah J, Wang A Ting   Autism from developmental and neuropsychological perspectives Annual review of clinical psychology, 2006; 2(3): 327-55.
Wood Jeffrey J, Piacentini John C, Southam-Gerow Michael, Chu Brian C, Sigman Marian   Family cognitive behavioral therapy for child anxiety disorders Journal of the American Academy of Child and Adolescent Psychiatry, 2006; 45(3): 314-21.
Dapretto Mirella, Davies Mari S, Pfeifer Jennifer H, Scott Ashley A, Sigman Marian, Bookheimer Susan Y, Iacoboni Marco   Understanding emotions in others: mirror neuron dysfunction in children with autism spectrum disorders Nature neuroscience, 2006; 9(1): 28-30.
Lord Catherine, Wagner Ann, Rogers Sally, Szatmari Peter, Aman Michael, Charman Tony, Dawson Geraldine, Durand V Mark, Grossman Lee, Guthrie Donald, Harris Sandra, Kasari Connie, Marcus Lee, Murphy Susan, Odom Samuel, Pickles Andrew, Scahill Lawrence, Shaw Evelyn, Siegel Bryna, Sigman Marian, Stone Wendy, Smith Tristram, Yoder Paul   Challenges in evaluating psychosocial interventions for Autistic Spectrum Disorders Journal of autism and developmental disorders, 2005; 35(6): 695-708; discussion 709-11.
Sigman Marian, Whaley Shannon E, Neumann Charlotte G, Bwibo Nimrod, Guthrie Donald, Weiss Robert E, Liang Li-Jung, Murphy Suzanne P   Diet quality affects the playground activities of Kenyan children Food and nutrition bulletin, 2005; 26(2 Suppl 2): S202-12.
McGovern Corina W, Sigman Marian   Continuity and change from early childhood to adolescence in autism Journal of child psychology and psychiatry, and allied disciplines, 2005; 46(4): 401-8.
Gernsbacher Morton A, Dissanayake Cheryl, Goldsmith H Hill, Mundy Peter C, Rogers Sally J, Sigman Marian   Autism and deficits in attachment behavior Science (New York, N.Y.), 2005; 307(5713): 1201-3; author reply 1201-3.
Luyster Rhiannon, Richler Jennifer, Risi Susan, Hsu Wan-Ling, Dawson Geraldine, Bernier Raphael, Dunn Michelle, Hepburn Susan, Hyman Susan L, McMahon William M, Goudie-Nice Julie, Minshew Nancy, Rogers Sally, Sigman Marian, Spence M Anne, Goldberg Wendy A, Tager-Flusberg Helen, Volkmar Fred R, Lord Catherine   Early regression in social communication in autism spectrum disorders: a CPEA Study Developmental neuropsychology, 2005; 27(3): 311-36.
Sigman Marian, McGovern Corina W   Improvement in cognitive and language skills from preschool to adolescence in autism Journal of autism and developmental disorders, 2005; 35(1): 15-23.
Bono Michael A, Daley L Tamara, Sigman Marian   Relations among joint attention, amount of intervention and language gain in autism Journal of autism and developmental disorders, 2004; 34(5): 495-505.
Moore Phoebe S, Whaley Shannon E, Sigman Marian   Interactions between mothers and children: impacts of maternal and child anxiety Journal of abnormal psychology, 2004; 113(3): 471-6.
Sigman Marian, Dijamco Angeline, Gratier Maya, Rozga Agata   Early detection of core deficits in autism Mental retardation and developmental disabilities research reviews, 2004; 10(4): 221-33.
Wang A Ting, Dapretto Mirella, Hariri Ahmad R, Sigman Marian, Bookheimer Susan Y   Neural correlates of facial affect processing in children and adolescents with autism spectrum disorder Journal of the American Academy of Child and Adolescent Psychiatry, 2004; 43(4): 481-90.
Neumann Charlotte G, Bwibo Nimrod O, Murphy Suzanne P, Sigman Marian, Whaley Shannon, Allen Lindsay H, Guthrie Donald, Weiss Robert E, Demment Montague W   Animal source foods improve dietary quality, micronutrient status, growth and cognitive function in Kenyan school children: background, study design and baseline findings The Journal of nutrition, 2003; 133(11 Suppl 2): 3941S-3949S.
Whaley Shannon E, Sigman Marian, Neumann Charlotte, Bwibo Nimrod, Guthrie Donald, Weiss Robert E, Alber Susan, Murphy Suzanne P   The impact of dietary intervention on the cognitive development of Kenyan school children The Journal of nutrition, 2003; 133(11 Suppl 2): 3965S-3971S.
Sigman Marian, Dissanayake Cheryl, Corona Rosalie, Espinosa Michael   Social and cardiac responses of young children with autism Autism : the international journal of research and practice, 2003; 7(2): 205-16.
Daley Tamara C, Whaley Shannon E, Sigman Marian D, Espinosa Michael P, Neumann Charlotte   IQ on the rise: the Flynn effect in rural Kenyan children Psychological science : a journal of the American Psychological Society / APS, 2003; 14(3): 215-9.
Wood Jeffrey J, McLeod Bryce D, Sigman Marian, Hwang Wei-Chin, Chu Brian C   Parenting and childhood anxiety: theory, empirical findings, and future directions Journal of child psychology and psychiatry, and allied disciplines, 2003; 44(1): 134-51.
Siller Michael, Sigman Marian   The behaviors of parents of children with autism predict the subsequent development of their children's communication Journal of autism and developmental disorders, 2002; 32(2): 77-89.
Daley Tamara C, Sigman Marian D   Diagnostic conceptualization of autism among Indian psychiatrists, psychologists, and pediatricians Journal of autism and developmental disorders, 2002; 32(1): 13-23.
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