David Krantz, M.D., Ph.D.
Work Phone Number:
Gonda Building, Rm 3357C
695 Charles Young Drive
Los Angeles, CA 90095
Hatos Center for Neuropharmacology
Psychiatry and Biobehavioral Sciences
ACCESS Program: Neuroscience IDP
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Brain Research Institute
Center for Neurodegenerative Disease Studies
Molecular Toxicology IDP
Awards and Honors:
UCLA Neuropsychiatric Hospital
UCSF Department of Neurology
David Krantz is an Associate Professor in Residence in the Department of Psychiatry and Biobehavioral Sciences at the David Geffen School of Medicine at UCLA. An undergraduate at Brown University, he completed an MD/PhD in the Medical Scientist Training Program at UCLA in 1991, where he performed his dissertation on Drosophila eye development with Larry Zipursky. After a residency in psychiatry at UCLA, he was awarded a Howard Hughes Postdoctoral Fellowship for Physicians to investigate the regulation of vesicular neurotransmitter transporters in Robert Edwards' laboratory at UCSF. He returned to UCLA in 2000, and is currently using Drosophila to study how changes in the function of neurotransmitter transporters may influence synaptic transmission and behavior.
Chen Audrey, Ng Fanny, Lebestky Tim, Grygoruk Anna, Djapri Christine, Lawal Hakeem O, Zaveri Harshul A, Mehanzel Filmon, Najibi Rod, Seidman Gabriel, Murphy Niall P, Kelly Rachel L, Ackerson Larry C, Maidment Nigel T, Jackson F Rob, Krantz David E
Dispensable, redundant, complementary, and cooperative roles of
dopamine, octopamine, and serotonin in Drosophila melanogaster.
Brooks Elizabeth S, Greer Christina L, Romero-Calder贸n Rafael, Serway Christine N, Grygoruk Anna, Haimovitz Jasmine M, Nguyen Bac T, Najibi Rod, Tabone Christopher J, de Belle J Steven, Krantz David E
A putative vesicular transporter expressed in Drosophila mushroom
bodies that mediates sexual behavior may define a neurotransmitter
Fei Hao, Chow Dawnis M, Chen Audrey, Romero-Calder贸n Rafael, Ong Wei S, Ackerson Larry C, Maidment Nigel T, Simpson Julie H, Frye Mark A, Krantz David E
Mutation of the Drosophila vesicular GABA transporter disrupts visual
The Journal of experimental biology,
2010; 213(Pt 10):
Cheli Ver贸nica T, Daniels Richard W, Godoy Ruth, Hoyle Diego J, Kandachar Vasundhara, Starcevic Marta, Martinez-Agosto Julian A, Poole Stephen, DiAntonio Aaron, Lloyd Vett K, Chang Henry C, Krantz David E, Dell'Angelica Esteban C
Genetic modifiers of abnormal organelle biogenesis in a Drosophila
model of BLOC-1 deficiency.
Human molecular genetics,
Mosharov Eugene V, Larsen Kristin E, Kanter Ellen, Phillips Kester A, Wilson Krystal, Schmitz Yvonne, Krantz David E, Kobayashi Kazuto, Edwards Robert H, Sulzer David
Interplay between cytosolic dopamine, calcium, and alpha-synuclein
causes selective death of substantia nigra neurons.
Simon, Daniels, Romero-Calder騨, Grygoruk, Chang, Najibi, Shamouelian, Salazar, Solomon, Ackerson, Maidment, Diantonio, Krantz
Drosophila Vesicular Monoamine Transporter Mutants can adapt to
Reduced or Eliminated Vesicular Stores of Dopamine and Serotonin.
Romero-Calder髇 Rafael, Uhlenbrock Guido, Borycz Jolanta, Simon Anne F, Grygoruk Anna, Yee Susan K, Shyer Amy, Ackerson Larry C, Maidment Nigel T, Meinertzhagen Ian A, Hovemann Bernhard T, Krantz David E
A glial variant of the vesicular monoamine transporter is required to
store histamine in the Drosophila visual system.
Greer Christina L, Grygoruk Anna, Patton David E, Ley Brett, Romero-Calderon Rafael, Chang Hui-Yun, Houshyar Roozbeh, Bainton Roland J, Diantonio Aaron, Krantz David E
A splice variant of the Drosophila vesicular monoamine transporter
contains a conserved trafficking domain and functions in the storage
of dopamine, serotonin, and octopamine.
Journal of neurobiology,