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Arthur Brody, M.D.

Contact Information:

Work Phone Number:

310-268-4778

Mailing Address:

300 UCLA Medical Plaza, Suite 2200
Los Angeles, CA 90095
UNITED STATES

Email Address:

abrody@ucla.edu

Professor in Residence, Psychiatry and Biobehavioral Sciences

Hatos Center for Neuropharmacology

Neuroscience IDP

Member, Brain Research Institute


A Short Biography:

Dr. Brody performs brain imaging research on cigarette smokers to examine molecular and regional activity aspects of smoking behavior. Specifically, brain function, changes in dopamine concentration, and changes in nicotine receptor availability are being examined in response to a range of smoking behavior and treatments for cigarette smoking.

Awards and Honors:

UCLA Neuropsychiatric Hospital
UCLA Neuropsychiatric Hospital
UCLA Neuropsychiatric Hospital

Detailed Biography:

Dr. Arthur L. Brody is a Professor-in-Residence in the UCLA Department of Psychiatry at the David Geffen School of Medicine. He received his undergraduate A.B. degree from Vassar College, M.D. degree from Tufts University School of Medicine, and psychiatry training at the UCLA Neuropsychiatric Institute. Following residency, he did a post-doctoral fellowship in research training funded by the National Institutes of Health (NIH). He currently serves as a grant reviewer on several NIH and Department of Veterans Affairs committees, and is an assistant editor for the journals Neuropsychopharmacology and Addiction. He is also the director of the Greater Los Angeles VA Smoking Cessation Programs and a Distinguished Fellow of the American Psychiatric Association.

Publications:

Brody Arthur L, Cook Ian A   Manipulation of cigarette craving with transcranial magnetic stimulation Biological psychiatry, 2011; 70(8): 702-3.
Brody Arthur L, Mandelkern Mark A, London Edythe D, Khan Aliyah, Kozman Daniel, Costello Matthew R, Vellios Evan E, Archie Meena M, Bascom Rebecca, Mukhin Alexey G   Effect of secondhand smoke on occupancy of nicotinic acetylcholine receptors in brain Archives of general psychiatry, 2011; 68(9): 953-60.
Culbertson Christopher S, Bramen Jennifer, Cohen Mark S, London Edythe D, Olmstead Richard E, Gan Joanna J, Costello Matthew R, Shulenberger Stephanie, Mandelkern Mark A, Brody Arthur L   Effect of bupropion treatment on brain activation induced by cigarette-related cues in smokers Archives of general psychiatry, 2011; 68(5): 505-15.
Culbertson Christopher, Nicolas Sam, Zaharovits Itay, London Edythe D, De La Garza Richard, Brody Arthur L, Newton Thomas F   Methamphetamine craving induced in an online virtual reality environment Pharmacology, biochemistry, and behavior, 2010; 96(4): 454-60.
Brody Arthur L, London Edythe D, Olmstead Richard E, Allen-Martinez Zoe, Shulenberger Stephanie, Costello Matthew R, Abrams Anna L, Scheibal David, Farahi Judah, Shoptaw Steven, Mandelkern Mark A   Smoking-induced change in intrasynaptic dopamine concentration: effect of treatment for Tobacco Dependence Psychiatry research, 2010; 183(3): 218-24.
Costello Matthew R, Mandelkern Mark A, Shoptaw Stephen, Shulenberger Stephanie, Baker Stephanie K, Abrams Anna L, Xia Catherine, London Edythe D, Brody Arthur L   Effects of treatment for tobacco dependence on resting cerebral glucose metabolism Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010; 35(3): 605-12.
Azizian Allen, Nestor Liam J, Payer Doris, Monterosso John R, Brody Arthur L, London Edythe D   Smoking reduces conflict-related anterior cingulate activity in abstinent cigarette smokers performing a Stroop task Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010; 35(3): 775-82.
Lee Buyean, London Edythe D, Poldrack Russell A, Farahi Judah, Nacca Angelo, Monterosso John R, Mumford Jeanette A, Bokarius Andrew V, Dahlbom Magnus, Mukherjee Jogeshwar, Bilder Robert M, Brody Arthur L, Mandelkern Mark A   Striatal dopamine d2/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(47): 14734-40.
Brody Arthur L, Mandelkern Mark A, Costello Matthew R, Abrams Anna L, Scheibal David, Farahi Judah, London Edythe D, Olmstead Richard E, Rose Jed E, Mukhin Alexey G   Brain nicotinic acetylcholine receptor occupancy: effect of smoking a denicotinized cigarette The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), 2009; 12(3): 305-16.
Sharma Anil, Brody Arthur L   In vivo brain imaging of human exposure to nicotine and tobacco Handbook of experimental pharmacology, 2009; 12(192): 145-71.
Brody Arthur L, Mandelkern Mark A, Olmstead Richard E, Allen-Martinez Zoe, Scheibal David, Abrams Anna L, Costello Matthew R, Farahi Judah, Saxena Sanjaya, Monterosso John, London Edythe D   Ventral striatal dopamine release in response to smoking a regular vs a denicotinized cigarette Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2009; 34(2): 282-9.
Xu Jiansong, Azizian Allen, Monterosso John, Domier Catherine P, Brody Arthur L, Fong Timothy W, London Edythe D   Gender effects on mood and cigarette craving during early abstinence and resumption of smoking Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2008; 10(11): 1653-61.
Azizian Allen, Monterosso John R, Brody Arthur L, Simon Sara L, London Edythe D   Severity of nicotine dependence moderates performance on perceptual-motor tests of attention Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2008; 10(4): 599-606.
Domier Catherine P, Monterosso John R, Brody Arthur L, Simon Sara L, Mendrek Adrianna, Olmstead Richard, Jarvik Murray E, Cohen Mark S, London Edythe D   Effects of cigarette smoking and abstinence on Stroop task performance Psychopharmacology, 2007; 195(1): 1-9.
Brody Arthur L, Mandelkern Mark A, Olmstead Richard E, Jou Jennifer, Tiongson Emmanuelle, Allen Valerie, Scheibal David, London Edythe D, Monterosso John R, Tiffany Stephen T, Korb Alex, Gan Joanna J, Cohen Mark S   Neural substrates of resisting craving during cigarette cue exposure Biological psychiatry, 2007; 62(6): 642-51.
Saxena Sanjaya, Brody Arthur L, Maidment Karron M, Baxter Lewis R   Paroxetine treatment of compulsive hoarding Journal of psychiatric research, 2007; 41(6): 481-7.
Xu Jiansong, Mendrek Adrianna, Cohen Mark S, Monterosso John, Simon Sara, Jarvik Murray, Olmstead Richard, Brody Arthur L, Ernst Monique, London Edythe D   Effect of cigarette smoking on prefrontal cortical function in nondeprived smokers performing the Stroop Task Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007; 32(6): 1421-8.
Gershon Grand Risa B, Hwang Sun, Han Juliette, George Tony, Brody Arthur L   Short-term naturalistic treatment outcomes in cigarette smokers with substance abuse and/or mental illness The Journal of clinical psychiatry, 2007; 68(6): 892-8; quiz 980-1.
Xu Jiansong, Mendrek Adrianna, Cohen Mark S, Monterosso John, Simon Sara, Brody Arthur L, Jarvik Murray, Rodriguez Paul, Ernst Monique, London Edythe D   Effects of acute smoking on brain activity vary with abstinence in smokers performing the N-Back task: a preliminary study Psychiatry research, 2006; 148(2-3): 103-9.
Brody Arthur L, Mandelkern Mark A, London Edythe D, Olmstead Richard E, Farahi Judah, Scheibal David, Jou Jennifer, Allen Valerie, Tiongson Emmanuelle, Chefer Svetlana I, Koren Andrei O, Mukhin Alexey G   Cigarette smoking saturates brain alpha 4 beta 2 nicotinic acetylcholine receptors Archives of general psychiatry, 2006; 63(8): 907-15.
Brody Arthur L   Functional brain imaging of tobacco use and dependence Journal of psychiatric research, 2006; 40(5): 404-18.
Brody Arthur L, Mandelkern Mark A, Olmstead Richard E, Scheibal David, Hahn Emily, Shiraga Sharon, Zamora-Paja Eleanor, Farahi Judah, Saxena Sanjaya, London Edythe D, McCracken James T   Gene variants of brain dopamine pathways and smoking-induced dopamine release in the ventral caudate/nucleus accumbens Archives of general psychiatry, 2006; 63(7): 808-16.
Mendrek Adrianna, Monterosso John, Simon Sara L, Jarvik Murray, Brody Arthur, Olmstead Richard, Domier Catherine P, Cohen Mark S, Ernst Monique, London Edythe D   Working memory in cigarette smokers: comparison to non-smokers and effects of abstinence Addictive behaviors, 2006; 31(5): 833-44.
London Edythe D, Berman Steven M, Voytek Bradley, Simon Sara L, Mandelkern Mark A, Monterosso John, Thompson Paul M, Brody Arthur L, Geaga Jennifer A, Hong Michael S, Hayashi Kiralee M, Rawson Richard A, Ling Walter   Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers Biological psychiatry, 2005; 58(10): 770-8.
Obrzut Sebastian L, Koren Andrei O, Mandelkern Mark A, Brody Arthur L, Hoh Carl K, London Edythe D   Whole-body radiation dosimetry of 2-[18F]Fluoro-A-85380 in human PET imaging studies Nuclear medicine and biology, 2005; 32(8): 869-74.
Voytek Bradley, Berman Steven M, Hassid B Daniel, Simon Sara L, Mandelkern Mark A, Brody Arthur L, Monterosso John, Ling Walter, London Edythe D   Differences in regional brain metabolism associated with marijuana abuse in methamphetamine abusers Synapse (New York, N.Y.), 2005; 57(2): 113-5.
Xu Jiansong, Mendrek Adrianna, Cohen Mark S, Monterosso John, Rodriguez Paul, Simon Sara L, Brody Arthur, Jarvik Murray, Domier Catherine P, Olmstead Richard, Ernst Monique, London Edythe D   Brain activity in cigarette smokers performing a working memory task: effect of smoking abstinence Biological psychiatry, 2005; 58(2): 143-50.
Brody Arthur L, Olmstead Richard E, London Edythe D, Farahi Judah, Meyer Jeffrey H, Grossman Paul, Lee Grace S, Huang Joe, Hahn Emily L, Mandelkern Mark A   Smoking-induced ventral striatum dopamine release The American journal of psychiatry, 2004; 161(7): 1211-8.
Saxena Sanjaya, Brody Arthur L, Maidment Karron M, Smith Erlyn C, Zohrabi Narineh, Katz Elyse, Baker Stephanie K, Baxter Lewis R   Cerebral glucose metabolism in obsessive-compulsive hoarding The American journal of psychiatry, 2004; 161(6): 1038-48.
Brody Arthur L, Mandelkern Mark A, Lee Grace, Smith Erlyn, Sadeghi Mary, Saxena Sanjaya, Jarvik Murray E, London Edythe D   Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study Psychiatry research, 2004; 130(3): 269-81.
Brody Arthur L, Mandelkern Mark A, Jarvik Murray E, Lee Grace S, Smith Erlyn C, Huang Joe C, Bota Robert G, Bartzokis George, London Edythe D   Differences between smokers and nonsmokers in regional gray matter volumes and densities Biological psychiatry, 2004; 55(1): 77-84.
Saxena Sanjaya, Brody Arthur L, Ho Matthew L, Zohrabi Narineh, Maidment Karron M, Baxter Lewis R   Differential brain metabolic predictors of response to paroxetine in obsessive-compulsive disorder versus major depression The American journal of psychiatry, 2003; 160(3): 522-32.
Brody Arthur L, Mandelkern Mark A, London Edythe D, Childress Anna Rose, Lee Grace S, Bota Robert G, Ho Matthew L, Saxena Sanjaya, Baxter Lewis R, Madsen Damian, Jarvik Murray E   Brain metabolic changes during cigarette craving Archives of general psychiatry, 2002; 59(12): 1162-72.
Saxena Sanjaya, Brody Arthur L, Ho Matthew L, Alborzian Shervin, Maidment Karron M, Zohrabi Narineh, Ho Mai K, Huang Sung-Cheng, Wu Hsiao-Ming, Baxter Lewis R   Differential cerebral metabolic changes with paroxetine treatment of obsessive-compulsive disorder vs major depression Archives of general psychiatry, 2002; 59(3): 250-61.
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