Peter Anton, M.D.

A Short Biography:

Dr. Anton is a professor of medicine within the UCLA Vatche and Tamar Manoukian Division of Digestive Diseases and a member of the UCLA AIDS Institute. He was founding director of the UCLA Center for HIV Prevention Research (CPR), which operated from 2003-2018, and director of the UCLA Center for AIDS Research (CFAR) Mucosal Immunology Core Laboratory, which operated from 1987-2018. He also served as past co-director of the Center for Inflammatory Bowel Disease at UCLA.

Dr. Anton graduated magna cum laude from Harvard University in 1977 and received his MD from Case Western Reserve University in 1983. He did fellowship work at the Cholera Hospital, ICDDR, in Bangladesh in 1983 and a year fellowship in pathology in 1981 in Cleveland’s Institute of Pathology. He performed his internship and residency in internal medicine at Brigham and Women’s Hospital in Boston Massachusetts. Dr. Anton began in his work at UCLA in 1986 with a gastroenterology fellowship and has been on faculty since 1989.

Dr. Anton’s research focuses on the degree of mucosal inflammation and altered co-receptor expression associated with HIV infection and associated therapeutic interventions, the potential use of the mucosa as a route of HIV immunization with various HIV vaccine candidates as well as microbicides for HIV mucosal prevention, investigating the interaction of HSV and HIV in mucosal pathogenesis and efforts to clarify the role of compartments in HIV pathogenesis.

He has been PI on over 30 clinical trials including two Phase I HIV vaccine trials and two Phase I anti-HIV topical microbicide trials. He recently completed research as PI of the NIH IPCP U19 award “Microbicide Development Program” (MDP), with national/international sub-study sites, focusing on a developmental pipeline for rectal microbicides. These rectal microbicide efforts have continued with both the Clinical Trials Project within the second IPCP U19 Combination HIV Antiretroviral Rectal Microbicide (CHARM) which has six exploratory pre-Phase I microbicide trials and JHU’s DREAM project. His research has expanded into delayed-release vaginal drug delivery and IM/injectable drug delivery with Oak Crest Institute of Sciences’ U19 and Northwestern University’s UM1 SLAP-HIV.

Dr. Anton is active in several NIH-sponsored national HIV networks including the AIDS Clinical Trial Group (ACTG), HIV Vaccine Trials Network (HVTN), HIV Clinical Pharmacology Quality Assurance Program Advisory Board (CPQA AB), HIV Prevention Trials Network (HPTN), HIV/AIDS Network Coordination (HANC), the Microbicide Trials Network (MTN) and the HVTN Mucosal Immunology Focus Group (HVTN MIG).


Work Titles
UCLA Professor, Vatche and Tamar Manoukian Division of Digestive Diseases
Education:
Degrees:
M.D., Case Western Reserve Univ School of Medicine, 1983
Fellowship:
1986 - 1989 UCLA School of Medicine
Internship:
1983 - 1984 Brigham & Women's Hospital
Residency:
1984 - 1986 Brigham & Women's Hospital

Contact Information:

Publications:

A selected list of publications:

Pines Heather A, Gorbach Pamina M, Weiss Robert E, Hess Kristen, Murphy Ryan, Saunders Terry, Brown Joelle, Anton Peter A, Cranston Ross D   Acceptability of Potential Rectal Microbicide Delivery Systems for HIV Prevention: A Randomized Crossover Trial AIDS and behavior, 2012; .
Richardson-Harman Nicola, Mauck Christine, McGowan Ian, Anton Peter   Dose-response relationship between tissue concentrations of UC781 and explant infectibility with HIV type 1 in the RMP-01 rectal safety study AIDS research and human retroviruses, 2012; 28(11): 1422-33.
Yuan Pu-Qing, Wu S Vincent, Elliott Julie, Anton Peter A, Chatzaki Ekaterini, Million Mulugeta, Taché Yvette   Expression of corticotropin releasing factor receptor type 1 (CRF1) in the human gastrointestinal tract and upregulation in the colonic mucosa in patients with ulcerative colitis Peptides, 2012; 38(1): 62-9.
Anton Peter A, Cranston Ross D, Kashuba Angela, Hendrix Craig W, Bumpus Namandjé N, Richardson-Harman Nicola, Elliott Julie, Janocko Laura, Khanukhova Elena, Dennis Robert, Cumberland William G, Ju Chuan, Carballo-Diéguez Alex, Mauck Christine, McGowan Ian   RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarate AIDS research and human retroviruses, 2012; 28(11): 1412-21.
Burrell Earl R, Pines Heather A, Robbie Edward, Coleman Leonardo, Murphy Ryan D, Hess Kristen L, Anton Peter, Gorbach Pamina M   Use of the location-based social networking application GRINDR as a recruitment tool in rectal microbicide development research AIDS and behavior, 2012; 16(7): 1816-20.
Anton Peter A   Future prospects and perspectives on microbicides Current HIV research, 2012; 10(1): 113-5.

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