Ira Kurtz

Title(s)Professor, Medicine
SchoolMedicine
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    Collapse Overview 
    Collapse Overview
    Dr. Ira Kurtz holds the Max Factor Family Foundation Chair in Nephrology.

    Collapse Research 
    Collapse Research Activities and Funding
    The Biology of NBCe1 in Health and Disease
    NIH R01DK077162Dec 1, 2006 - Mar 31, 2024
    Role: Principal Investigator
    Modulation of Electrogenic Sodium Bicarbonate Transport
    NIH R01DK063125Jan 1, 2003 - Dec 31, 2008
    Role: Principal Investigator
    Biology of Sodium Bicarbonate Transport
    NIH R01DK058563Mar 1, 2001 - Aug 31, 2013
    Role: Principal Investigator
    Nephrology Scientist Training Grant
    NIH T32DK007789Sep 30, 2000 - Dec 31, 2017
    Role: Principal Investigator
    NA+ AND CL- TRANSPORT IN THE MAMMALIAN PROXIMAL TUBULE
    NIH R01DK046976May 20, 1997 - Apr 30, 2001
    Role: Principal Investigator
    CONFOCAL MICROSCOPY--COLLECTING DUCT PHI REGULATION
    NIH R01DK041212Aug 1, 1991 - Jul 31, 1997
    Role: Principal Investigator
    INTRACELLULAR PH REGULATION IN THE KIDNEY TUBULE
    NIH R29DK039212Aug 15, 1987 - Dec 31, 1991
    Role: Principal Investigator
    INTRACELLULAR PH REGULATION IN THE MEDULLARY TUBULE
    NIH R23DK036324Jan 1, 1986 - Dec 31, 1988
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Data-driven prediction of continuous renal replacement therapy survival. Res Sq. 2023 Nov 14. Zamanzadeh D, Feng J, Petousis P, Vepa A, Sarrafzadeh M, Karumanchi SA, Bui AAT, Kurtz I. PMID: 38014280; PMCID: PMC10680921.
      View in: PubMed   Mentions:
    2. Coarse-grained molecular dynamics simulations of lipid-protein interactions in SLC4 proteins. bioRxiv. 2023 Jun 28. Zhekova HR, Ramirez-Echemendía DP, Sejdiu BI, Pushkin A, Tieleman DP, Kurtz I. PMID: 37425774; PMCID: PMC10327080.
      View in: PubMed   Mentions:
    3. Impact of various buffers and weak bases on lysosomal and intracellular pH: Implications for infectivity of SARS-CoV-2. FASEB Bioadv. 2023 Apr; 5(4):149-155. Kraut JA, Cheetham-Wilkinson IJ, Swan LE, Stagi M, Kurtz I. PMID: 37020747; PMCID: PMC10068769.
      View in: PubMed   Mentions:
    4. Base (HCO3-/CO32-) Transport Properties of SLC4 Proteins: New Insights in Acid-Base Kidney Physiology. J Am Soc Nephrol. 2023 01 01; 34(1):8-13. Kurtz I, Schwartz GJ. PMID: 36719145; PMCID: PMC10101619.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations. Commun Biol. 2022 12 14; 5(1):1372. Zhekova HR, Jiang J, Wang W, Tsirulnikov K, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Tieleman DP, Hong Zhou Z, Pushkin A, Kurtz I. PMID: 36517642; PMCID: PMC9751308.
      View in: PubMed   Mentions: 7  Translation:AnimalsCells
    6. Calcium Transport in the Kidney and Disease Processes. Front Endocrinol (Lausanne). 2021; 12:762130. Hanna RM, Ahdoot RS, Kalantar-Zadeh K, Ghobry L, Kurtz I. PMID: 35299844; PMCID: PMC8922474.
      View in: PubMed   Mentions: 4     Fields:    
    7. Intravitreal vascular endothelial growth factors hypertension, proteinuria, and renal injury: a concise review. Curr Opin Nephrol Hypertens. 2022 01 01; 31(1):47-56. Hanna RM, Ahdoot RS, Kim MS, Jhaveri KD, Kalantar-Zadeh K, Kurtz IB. PMID: 34750330.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    8. Publisher Correction: Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE. Nat Commun. 2021 Oct 13; 12(1):6083. Wang W, Tsirulnikov K, Zhekova HR, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Zhou ZH, Pushkin A, Kurtz I. PMID: 34645810; PMCID: PMC8514430.
      View in: PubMed   Mentions: 1     Fields:    
    9. Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE. Nat Commun. 2021 09 28; 12(1):5690. Wang W, Tsirulnikov K, Zhekova HR, Kayik G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Zhou ZH, Pushkin A, Kurtz I. PMID: 34584093; PMCID: PMC8478935.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    10. Identification of multiple substrate binding sites in SLC4 transporters in the outward-facing conformation: Insights into the transport mechanism. J Biol Chem. 2021 Jan-Jun; 296:100724. Zhekova HR, Pushkin A, Kayik G, Kao L, Azimov R, Abuladze N, Kurtz D, Damergi M, Noskov SY, Kurtz I. PMID: 33932403; PMCID: PMC8191340.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    11. Review of intravitreal VEGF inhibitor toxicity and report of collapsing FSGS with TMA in a patient with age-related macular degeneration. Clin Kidney J. 2021 Oct; 14(10):2158-2165. Phadke G, Hanna RM, Ferrey A, Torres EA, Singla A, Kaushal A, Kalantar-Zadeh K, Kurtz I, Jhaveri KD. PMID: 34603693; PMCID: PMC8483684.
      View in: PubMed   Mentions: 6  
    12. Host Genetic Background and Gut Microbiota Contribute to Differential Metabolic Responses to Fructose Consumption in Mice. J Nutr. 2020 10 12; 150(10):2716-2728. Ahn IS, Lang JM, Olson CA, Diamante G, Zhang G, Ying Z, Byun HR, Cely I, Ding J, Cohn P, Kurtz I, Gomez-Pinilla F, Lusis AJ, Hsiao EY, Yang X. PMID: 32856048; PMCID: PMC7549307.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    13. Thrombotic Microangiopathy and Acute Kidney Injury Induced After Intravitreal Injection of Vascular Endothelial Growth Factor Inhibitors VEGF Blockade-Related TMA After Intravitreal Use. Front Med (Lausanne). 2020; 7:579603. Hanna RM, Tran NT, Patel SS, Hou J, Jhaveri KD, Parikh R, Selamet U, Ghobry L, Wassef O, Barsoum M, Bijol V, Kalantar-Zadeh K, Pai A, Amin A, Kupperman B, Kurtz IB. PMID: 33117836; PMCID: PMC7577346.
      View in: PubMed   Mentions: 11  
    14. Refractory scleroderma renal crisis precipitated after high-dose oral corticosteroids and concurrent intravitreal injection of bevacizumab. SAGE Open Med Case Rep. 2020; 8:2050313X20952650. Hanna RM, Abdelnour L, Zuckerman JE, Ferrey AJ, Pai A, Vahabzadeh K, Wilson J, Torres EA, Kalantar-Zadeh K, Kurtz IB. PMID: 32913652; PMCID: PMC7443985.
      View in: PubMed   Mentions: 3  
    15. Energy Shortage in Human and Mouse Models of SLC4A11-Associated Corneal Endothelial Dystrophies. Invest Ophthalmol Vis Sci. 2020 07 01; 61(8):39. Zhang W, Frausto R, Chung DD, Griffis CG, Kao L, Chen A, Azimov R, Sampath AP, Kurtz I, Aldave AJ. PMID: 32721020; PMCID: PMC7425690.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    16. Diverse Clinical Presentations of C3 Dominant Glomerulonephritis. Front Med (Lausanne). 2020; 7:293. Hanna RM, Hou J, Hasnain H, Arman F, Selamet U, Wilson J, Olanrewaju S, Zuckerman JE, Barsoum M, Yabu JM, Kurtz I. PMID: 32695788; PMCID: PMC7338606.
      View in: PubMed   Mentions: 1  
    17. Worsening proteinuria and renal function after intravitreal vascular endothelial growth factor blockade for diabetic proliferative retinopathy. Clin Kidney J. 2020 Dec; 13(6):969-980. Shye M, Hanna RM, Patel SS, Tram-Tran N, Hou J, Mccannel C, Khalid M, Hanna M, Abdelnour L, Kurtz I. PMID: 33391740; PMCID: PMC7769550.
      View in: PubMed   Mentions: 17  
    18. Peroxidasin-mediated bromine enrichment of basement membranes. Proc Natl Acad Sci U S A. 2020 07 07; 117(27):15827-15836. He C, Song W, Weston TA, Tran C, Kurtz I, Zuckerman JE, Guagliardo P, Miner JH, Ivanov SV, Bougoure J, Hudson BG, Colon S, Voziyan PA, Bhave G, Fong LG, Young SG, Jiang H. PMID: 32571911; PMCID: PMC7354931.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    19. Phenotypic and functional characterization of corneal endothelial cells during in vitro expansion. Sci Rep. 2020 05 04; 10(1):7402. Frausto RF, Swamy VS, Peh GSL, Boere PM, Hanser EM, Chung DD, George BL, Morselli M, Kao L, Azimov R, Wu J, Pellegrini M, Kurtz I, Mehta JS, Aldave AJ. PMID: 32366916; PMCID: PMC7198491.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    20. Acute interstitial nephritis and drug-induced systemic lupus erythematosus due to chlorthalidone and amiodarone: A case report. SAGE Open Med Case Rep. 2020; 8:2050313X20910029. Selamet U, Hanna RM, Sisk A, Abdelnour L, Ghobry L, Kurtz I. PMID: 32166031; PMCID: PMC7052449.
      View in: PubMed   Mentions:
    21. Intravitreal bevacizumab-induced exacerbation of proteinuria in diabetic nephropathy, and amelioration by switching to ranibizumab. SAGE Open Med Case Rep. 2020; 8:2050313X20907033. Hanna RM, Abdelnour L, Hasnain H, Selamet U, Kurtz I. PMID: 32110410; PMCID: PMC7026818.
      View in: PubMed   Mentions: 17  
    22. Is the Osmolal Concentration of Ethanol Greater Than Its Molar Concentration? Front Med (Lausanne). 2019; 6:306. Nguyen MK, Song L, Kao L, Tong K, De La Cruz MJ, Rodriguez G, Nguyen MK, Nguyen DS, Kurtz I. PMID: 31970159; PMCID: PMC6960184.
      View in: PubMed   Mentions: 2  
    23. Slc4a11 disruption causes duct cell loss and impairs NaCl reabsorption in female mouse submandibular glands. Physiol Rep. 2019 12; 7(23):e14232. Yang NY, Mukaibo T, Gao X, Kurtz I, Melvin JE. PMID: 31833218; PMCID: PMC6908739.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    24. SLC4A11 function: evidence for H+(OH-) and NH3-H+ transport. Am J Physiol Cell Physiol. 2020 02 01; 318(2):C392-C405. Kao L, Azimov R, Shao XM, Abuladze N, Newman D, Zhekova H, Noskov S, Pushkin A, Kurtz I. PMID: 31774702; PMCID: PMC7052617.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    25. Equivalent Efficacy and Decreased Rate of Overcorrection in Patients With Syndrome of Inappropriate Secretion of Antidiuretic Hormone Given Very Low-Dose Tolvaptan. Kidney Med. 2020 Jan-Feb; 2(1):20-28. Hanna RM, Velez JC, Rastogi A, Nguyen MK, Kamgar MK, Moe K, Arman F, Hasnain H, Nobakht N, Selamet U, Kurtz I. PMID: 32734225; PMCID: PMC7380356.
      View in: PubMed   Mentions: 8  
    26. Successful use of eculizumab to treat atypical hemolytic uremic syndrome in patients with inflammatory bowel disease. Thromb J. 2019; 17:18. Hanna RM, Merin N, Burwick RM, Abdelnour L, Selamet U, Yanny B, Bui P, Fouad M, Kurtz I. PMID: 31516395; PMCID: PMC6732828.
      View in: PubMed   Mentions: 4  
    27. ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing. PLoS One. 2019; 14(6):e0218279. Frausto RF, Chung DD, Boere PM, Swamy VS, Duong HNV, Kao L, Azimov R, Zhang W, Carrigan L, Wong D, Morselli M, Zakharevich M, Hanser EM, Kassels AC, Kurtz I, Pellegrini M, Aldave AJ. PMID: 31194824; PMCID: PMC6564028.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    28. Atypical hemolytic uremic syndrome and complement blockade: established and emerging uses of complement inhibition. Curr Opin Nephrol Hypertens. 2019 05; 28(3):278-287. Hanna RM, Barsoum M, Vandross A, Kurtz I, Burwick R. PMID: 30865166.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    29. Expression of SLC4A11 protein in mouse and rat medulla: a candidate transporter involved in outer medullary ammonia recycling. Physiol Rep. 2019 05; 7(10):e14089. Gee MT, Kurtz I, Pannabecker TL. PMID: 31124301; PMCID: PMC6533174.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    30. Nephrotoxicity induced by intravitreal vascular endothelial growth factor inhibitors: emerging evidence. Kidney Int. 2019 09; 96(3):572-580. Hanna RM, Barsoum M, Arman F, Selamet U, Hasnain H, Kurtz I. PMID: 31229276.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    31. The apical Na+ -HCO3- cotransporter Slc4a7 (NBCn1) does not contribute to bicarbonate transport by mouse salivary gland ducts. J Cell Physiol. 2019 Feb 14. Yang NY, Mukaibo T, Kurtz I, Melvin JE. PMID: 30767201; PMCID: PMC6694005.
      View in: PubMed   Mentions: 3     Fields:    
    32. Impact of Individual Traits, Saturated Fat, and Protein Source on the Gut Microbiome. mBio. 2018 12 11; 9(6). Lang JM, Pan C, Cantor RM, Tang WHW, Garcia-Garcia JC, Kurtz I, Hazen SL, Bergeron N, Krauss RM, Lusis AJ. PMID: 30538180; PMCID: PMC6299478.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    33. A Novel Case of Pseudohyponatremia Caused by Hypercholesterolemia. Kidney Int Rep. 2019 Mar; 4(3):491-493. Song L, Hanna RM, Nguyen MK, Kurtz I, Wilson J. PMID: 30899877; PMCID: PMC6409396.
      View in: PubMed   Mentions: 5  
    34. Renal Tubular Acidosis: H+/Base and Ammonia Transport Abnormalities and Clinical Syndromes. Adv Chronic Kidney Dis. 2018 07; 25(4):334-350. Kurtz I. PMID: 30139460; PMCID: PMC6128697.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    35. CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1. Nat Commun. 2018 03 02; 9(1):900. Huynh KW, Jiang J, Abuladze N, Tsirulnikov K, Kao L, Shao X, Newman D, Azimov R, Pushkin A, Zhou ZH, Kurtz I. PMID: 29500354; PMCID: PMC5834491.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    36. Aminoacylase 3 Is a New Potential Marker and Therapeutic Target in Hepatocellular Carcinoma. J Cancer. 2018; 9(1):1-12. Tsirulnikov K, Duarte S, Ray A, Datta N, Zarrinpar A, Hwang L, Faull K, Pushkin A, Kurtz I. PMID: 29290764; PMCID: PMC5743706.
      View in: PubMed   Mentions: 2  
    37. Multifunctional ion transport properties of human SLC4A11: comparison of the SLC4A11-B and SLC4A11-C variants. Am J Physiol Cell Physiol. 2016 Nov 01; 311(5):C820-C830. Kao L, Azimov R, Shao XM, Frausto RF, Abuladze N, Newman D, Aldave AJ, Kurtz I. PMID: 27581649; PMCID: PMC5130583.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    38. SLC26A Gene Family Participate in pH Regulation during Enamel Maturation. PLoS One. 2015; 10(12):e0144703. Yin K, Lei Y, Wen X, Lacruz RS, Soleimani M, Kurtz I, Snead ML, White SN, Paine ML. PMID: 26671068; PMCID: PMC4679777.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    39. Interplay between disulfide bonding and N-glycosylation defines SLC4 Na+-coupled transporter extracellular topography. J Biol Chem. 2015 Feb 27; 290(9):5391-404. Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Kurtz I. PMID: 25568315; PMCID: PMC4342456.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    40. Intracellular Cl- as a signaling ion that potently regulates Na+/HCO3- transporters. Proc Natl Acad Sci U S A. 2015 Jan 20; 112(3):E329-37. Shcheynikov N, Son A, Hong JH, Yamazaki O, Ohana E, Kurtz I, Shin DM, Muallem S. PMID: 25561556; PMCID: PMC4311818.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    41. A novel delta current method for transport stoichiometry estimation. BMC Biophys. 2014; 7(1):14. Shao XM, Kao L, Kurtz I. PMID: 25558372; PMCID: PMC4274721.
      View in: PubMed   Mentions: 3  
    42. Treatment of acute non-anion gap metabolic acidosis. Clin Kidney J. 2015 Feb; 8(1):93-9. Kraut JA, Kurtz I. PMID: 25852932; PMCID: PMC4377741.
      View in: PubMed   Mentions: 13  
    43. Human SLC4A11-C functions as a DIDS-stimulatable H⁺(OH⁻) permeation pathway: partial correction of R109H mutant transport. Am J Physiol Cell Physiol. 2015 Jan 15; 308(2):C176-88. Kao L, Azimov R, Abuladze N, Newman D, Kurtz I. PMID: 25394471; PMCID: PMC4297769.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    44. Molecular mechanisms and regulation of urinary acidification. Compr Physiol. 2014 Oct; 4(4):1737-74. Kurtz I. PMID: 25428859; PMCID: PMC4590986.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    45. Defining the role of albumin infusion in cirrhosis-associated hyponatremia. Am J Physiol Gastrointest Liver Physiol. 2014 Jul 15; 307(2):G229-32. Nguyen MK, Ornekian V, Kao L, Butch AW, Kurtz I. PMID: 24833711.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    46. Prevention of the disrupted enamel phenotype in Slc4a4-null mice using explant organ culture maintained in a living host kidney capsule. PLoS One. 2014; 9(5):e97318. Wen X, Kurtz I, Paine ML. PMID: 24828138; PMCID: PMC4020772.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    47. NBCe1 as a model carrier for understanding the structure-function properties of Na⁺ -coupled SLC4 transporters in health and disease. Pflugers Arch. 2014 Aug; 466(8):1501-16. Kurtz I. PMID: 24515290; PMCID: PMC4096079.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    48. Proximal renal tubular acidosis mediated by mutations in NBCe1-A: unraveling the transporter's structure-functional properties. Front Physiol. 2013 Dec 19; 4:350. Kurtz I, Zhu Q. PMID: 24391589; PMCID: PMC3867943.
      View in: PubMed   Mentions: 13  
    49. Structure, function, and regulation of the SLC4 NBCe1 transporter and its role in causing proximal renal tubular acidosis. Curr Opin Nephrol Hypertens. 2013 Sep; 22(5):572-83. Kurtz I, Zhu Q. PMID: 23917030; PMCID: PMC4132186.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    50. Missense mutation T485S alters NBCe1-A electrogenicity causing proximal renal tubular acidosis. Am J Physiol Cell Physiol. 2013 Aug 15; 305(4):C392-405. Zhu Q, Shao XM, Kao L, Azimov R, Weinstein AM, Newman D, Liu W, Kurtz I. PMID: 23636456; PMCID: PMC3891219.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    51. Single particle electron microscopy analysis of the bovine anion exchanger 1 reveals a flexible linker connecting the cytoplasmic and membrane domains. PLoS One. 2013; 8(2):e55408. Jiang J, Magilnick N, Tsirulnikov K, Abuladze N, Atanasov I, Ge P, Narla M, Pushkin A, Zhou ZH, Kurtz I. PMID: 23393575; PMCID: PMC3564912.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    52. Topology of NBCe1 protein transmembrane segment 1 and structural effect of proximal renal tubular acidosis (pRTA) S427L mutation. J Biol Chem. 2013 Mar 15; 288(11):7894-7906. Zhu Q, Liu W, Kao L, Azimov R, Newman D, Abuladze N, Kurtz I. PMID: 23362273; PMCID: PMC3597827.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    53. Aminoacylase 3 binds to and cleaves the N-terminus of the hepatitis C virus core protein. FEBS Lett. 2012 Nov 02; 586(21):3799-804. Tsirulnikov K, Abuladze N, Vahi R, Hasnain H, Phillips M, Ryan CM, Atanasov I, Faull KF, Kurtz I, Pushkin A. PMID: 23010594; PMCID: PMC3483449.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    54. Expression of the sodium/calcium/potassium exchanger, NCKX4, in ameloblasts. Cells Tissues Organs. 2012; 196(6):501-9. Hu P, Lacruz RS, Smith CE, Smith SM, Kurtz I, Paine ML. PMID: 22677781; PMCID: PMC3535175.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    55. Integrin αIIbβ3 inside-out activation: an in situ conformational analysis reveals a new mechanism. J Biol Chem. 2012 Jun 29; 287(27):23255-65. Kurtz L, Kao L, Newman D, Kurtz I, Zhu Q. PMID: 22613710; PMCID: PMC3391112.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    56. A new technique for multiple re-use of planar patch clamp chips. J Neurosci Methods. 2012 Jul 15; 208(2):205-10. Kao L, Abuladze N, Shao XM, McKeegan K, Kurtz I. PMID: 22609774.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    57. The sodium-driven chloride/bicarbonate exchanger in presynaptic terminals. J Comp Neurol. 2012 May 01; 520(7):1481-92. Burette AC, Weinberg RJ, Sassani P, Abuladze N, Kao L, Kurtz I. PMID: 22102085; PMCID: PMC3856893.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    58. Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling. J Cell Physiol. 2012 May; 227(5):2264-75. Lacruz RS, Smith CE, Bringas P, Chen YB, Smith SM, Snead ML, Kurtz I, Hacia JG, Hubbard MJ, Paine ML. PMID: 21809343; PMCID: PMC3243804.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    59. Determination of membrane protein transporter oligomerization in native tissue using spatial fluorescence intensity fluctuation analysis. PLoS One. 2012; 7(4):e36215. Sergeev M, Godin AG, Kao L, Abuladze N, Wiseman PW, Kurtz I. PMID: 22558387; PMCID: PMC3338697.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    60. Requirements for ion and solute transport, and pH regulation during enamel maturation. J Cell Physiol. 2012 Apr; 227(4):1776-85. Lacruz RS, Smith CE, Moffatt P, Chang EH, Bromage TG, Bringas P, Nanci A, Baniwal SK, Zabner J, Welsh MJ, Kurtz I, Paine ML. PMID: 21732355; PMCID: PMC3373187.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    61. Identification of a pH-responsive DNA region upstream of the transcription start site of human NBCe1-B. Eur J Oral Sci. 2011 Dec; 119 Suppl 1:136-41. Snead CM, Smith SM, Sadeghein N, Lacruz RS, Hu P, Kurtz I, Paine ML. PMID: 22243239; PMCID: PMC3374727.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    62. Defining the buffering process by a triprotic acid without relying on Stewart-electroneutrality considerations. Theor Biol Med Model. 2011 Aug 17; 8:29. Nguyen MK, Kao L, Kurtz I. PMID: 21849064; PMCID: PMC3247848.
      View in: PubMed   Mentions: 1     Fields:    
    63. Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene). J Biol Chem. 2011 Sep 16; 286(37):32563-74. Kao L, Kurtz LM, Shao X, Papadopoulos MC, Liu L, Bok D, Nusinowitz S, Chen B, Stella SL, Andre M, Weinreb J, Luong SS, Piri N, Kwong JM, Newman D, Kurtz I. PMID: 21705333; PMCID: PMC3173174.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    64. Structures of aminoacylase 3 in complex with acetylated substrates. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17962-7. Hsieh JM, Tsirulnikov K, Sawaya MR, Magilnick N, Abuladze N, Kurtz I, Abramson J, Pushkin A. PMID: 20921362; PMCID: PMC2964198.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    65. Structural and functional characterization of the C-terminal transmembrane region of NBCe1-A. J Biol Chem. 2010 Nov 26; 285(48):37178-87. Zhu Q, Kao L, Azimov R, Abuladze N, Newman D, Pushkin A, Liu W, Chang C, Kurtz I. PMID: 20837482; PMCID: PMC2988324.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    66. The sodium bicarbonate cotransporter (NBCe1) is essential for normal development of mouse dentition. J Biol Chem. 2010 Aug 06; 285(32):24432-8. Lacruz RS, Nanci A, White SN, Wen X, Wang H, Zalzal SF, Luong VQ, Schuetter VL, Conti PS, Kurtz I, Paine ML. PMID: 20529845; PMCID: PMC2915679.
      View in: PubMed   Mentions: 50     Fields:    Translation:Animals
    67. Topological location and structural importance of the NBCe1-A residues mutated in proximal renal tubular acidosis. J Biol Chem. 2010 Apr 30; 285(18):13416-26. Zhu Q, Kao L, Azimov R, Newman D, Liu W, Pushkin A, Abuladze N, Kurtz I. PMID: 20197274; PMCID: PMC2859501.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    68. A survey of carbonic anhydrase mRNA expression in enamel cells. Biochem Biophys Res Commun. 2010 Mar 19; 393(4):883-7. Lacruz RS, Hilvo M, Kurtz I, Paine ML. PMID: 20175995; PMCID: PMC2843801.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    69. Transport of N-acetyl-S-(1,2-dichlorovinyl)-L-cysteine, a metabolite of trichloroethylene, by mouse multidrug resistance associated protein 2 (Mrp2). Toxicol Appl Pharmacol. 2010 Apr 15; 244(2):218-25. Tsirulnikov K, Abuladze N, Koag MC, Newman D, Scholz K, Bondar G, Zhu Q, Avliyakulov NK, Dekant W, Faull K, Kurtz I, Pushkin A. PMID: 20060011; PMCID: PMC2847015.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    70. Regulation of pH During Amelogenesis. Calcif Tissue Int. 2010 Feb; 86(2):91-103. Lacruz RS, Nanci A, Kurtz I, Wright JT, Paine ML. PMID: 20016979; PMCID: PMC2809306.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells
    71. Slc4a11 gene disruption in mice: cellular targets of sensorineuronal abnormalities. J Biol Chem. 2009 Sep 25; 284(39):26882-96. Lopez IA, Rosenblatt MI, Kim C, Galbraith GC, Jones SM, Kao L, Newman D, Liu W, Yeh S, Pushkin A, Abuladze N, Kurtz I. PMID: 19586905; PMCID: PMC2785376.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    72. Mouse aminoacylase 3: a metalloenzyme activated by cobalt and nickel. Biochim Biophys Acta. 2009 Jul; 1794(7):1049-57. Tsirulnikov K, Abuladze N, Newman D, Ryazantsev S, Wolak T, Magilnick N, Koag MC, Kurtz I, Pushkin A. PMID: 19362172; PMCID: PMC2735877.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    73. Calculation of the equilibrium pH in a multiple-buffered aqueous solution based on partitioning of proton buffering: a new predictive formula. Am J Physiol Renal Physiol. 2009 Jun; 296(6):F1521-9. Nguyen MK, Kao L, Kurtz I. PMID: 19339630; PMCID: PMC2692448.
      View in: PubMed   Mentions: 3     Fields:    
    74. NBCe1-A Transmembrane Segment 1 Lines the Ion Translocation Pathway. J Biol Chem. 2009 Mar 27; 284(13):8918-29. Zhu Q, Azimov R, Kao L, Newman D, Liu W, Abuladze N, Pushkin A, Kurtz I. PMID: 19158093; PMCID: PMC2659249.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    75. Oligomeric structure and minimal functional unit of the electrogenic sodium bicarbonate cotransporter NBCe1-A. J Biol Chem. 2008 Sep 26; 283(39):26782-94. Kao L, Sassani P, Azimov R, Pushkin A, Abuladze N, Peti-Peterdi J, Liu W, Newman D, Kurtz I. PMID: 18658147; PMCID: PMC2546552.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    76. G418-mediated ribosomal read-through of a nonsense mutation causing autosomal recessive proximal renal tubular acidosis. Am J Physiol Renal Physiol. 2008 Sep; 295(3):F633-41. Azimov R, Abuladze N, Sassani P, Newman D, Kao L, Liu W, Orozco N, Ruchala P, Pushkin A, Kurtz I. PMID: 18614622; PMCID: PMC2653109.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    77. Correction of hypervolaemic hypernatraemia by inducing negative Na+ and K+ balance in excess of negative water balance: a new quantitative approach. Nephrol Dial Transplant. 2008 Jul; 23(7):2223-7. Nguyen MK, Kurtz I. PMID: 18283087.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    78. Measurement of aminoacylases. Curr Protoc Toxicol. 2008 Feb; Chapter 6:Unit6.14. Pushkin A, Kurtz I. PMID: 23045009.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    79. Acid-base analysis: a critique of the Stewart and bicarbonate-centered approaches. Am J Physiol Renal Physiol. 2008 May; 294(5):F1009-31. Kurtz I, Kraut J, Ornekian V, Nguyen MK. PMID: 18184741.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimals
    80. Toxic alcohol ingestions: clinical features, diagnosis, and management. Clin J Am Soc Nephrol. 2008 Jan; 3(1):208-25. Kraut JA, Kurtz I. PMID: 18045860.
      View in: PubMed   Mentions: 95     Fields:    Translation:Humans
    81. Autosomal recessive CHED associated with novel compound heterozygous mutations in SLC4A11. Cornea. 2007 Aug; 26(7):896-900. Aldave AJ, Yellore VS, Bourla N, Momi RS, Khan MA, Salem AK, Rayner SA, Glasgow BJ, Kurtz I. PMID: 17667634.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    82. Structural characterization of dimeric murine aminoacylase III. FEBS Lett. 2007 May 01; 581(9):1898-902. Ryazantsev S, Abuladze N, Newman D, Bondar G, Kurtz I, Pushkin A. PMID: 17434493.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    83. A new method for determining plasma water content: application in pseudohyponatremia. Am J Physiol Renal Physiol. 2007 May; 292(5):F1652-6. Nguyen MK, Ornekian V, Butch AW, Kurtz I. PMID: 17299138.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    84. Acute lymphoblastic leukemia presenting as acute renal failure. Nat Clin Pract Nephrol. 2007 Feb; 3(2):106-10. Suh WM, Wainberg ZA, de Vos S, Cohen AH, Kurtz I, Nguyen MK. PMID: 17251998.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    85. Specificity of aminoacylase III-mediated deacetylation of mercapturic acids. Drug Metab Dispos. 2007 Jan; 35(1):43-50. Newman D, Abuladze N, Scholz K, Dekant W, Tsuprun V, Ryazantsev S, Bondar G, Sassani P, Kurtz I, Pushkin A. PMID: 17012540.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    86. Is the osmotically inactive sodium storage pool fixed or variable? J Appl Physiol (1985). 2007 Jan; 102(1):445-7. Nguyen MK, Kurtz I. PMID: 16916917.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    87. True hyponatremia secondary to intravenous immunoglobulin. Clin Exp Nephrol. 2006 Jun; 10(2):124-6. Nguyen MK, Rastogi A, Kurtz I. PMID: 16791398.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    88. Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: results of an online survey. Clin Exp Nephrol. 2006 Jun; 10(2):111-7. Kraut JA, Kurtz I. PMID: 16791396.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    89. Fatal hyponatremia in a young woman after ecstasy ingestion. Nat Clin Pract Nephrol. 2006 May; 2(5):283-8, quiz 289. Kalantar-Zadeh K, Nguyen MK, Chang R, Kurtz I. PMID: 16932441.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    90. SLC4 base (HCO3 -, CO3 2-) transporters: classification, function, structure, genetic diseases, and knockout models. Am J Physiol Renal Physiol. 2006 Mar; 290(3):F580-99. Pushkin A, Kurtz I. PMID: 16461757.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    91. Whole-body electrolyte-free water clearance: derivation and clinical utility in analyzing the pathogenesis of the dysnatremias. Clin Exp Nephrol. 2006 Mar; 10(1):19-24. Nguyen MK, Kurtz I. PMID: 16544174.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    92. Murine auditory brainstem evoked response: putative two-channel differentiation of peripheral and central neural pathways. J Neurosci Methods. 2006 Jun 15; 153(2):214-20. Galbraith G, Waschek J, Armstrong B, Edmond J, Lopez I, Liu W, Kurtz I. PMID: 16406043.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    93. Quantitative interrelationship between Gibbs-Donnan equilibrium, osmolality of body fluid compartments, and plasma water sodium concentration. J Appl Physiol (1985). 2006 Apr; 100(4):1293-300. Nguyen MK, Kurtz I. PMID: 16357067.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    94. Evolving concepts in the quantitative analysis of the determinants of the plasma water sodium concentration and the pathophysiology and treatment of the dysnatremias. Kidney Int. 2005 Nov; 68(5):1982-93. Kurtz I, Nguyen MK. PMID: 16221198.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    95. Time course of auditory impairment in mice lacking the electroneutral sodium bicarbonate cotransporter NBC3 (slc4a7). Brain Res Dev Brain Res. 2005 Nov 07; 160(1):63-77. Lopez IA, Acuna D, Galbraith G, Bok D, Ishiyama A, Liu W, Kurtz I. PMID: 16181686.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    96. Intercalated cell H+/OH- transporter expression is reduced in Slc26a4 null mice. Am J Physiol Renal Physiol. 2005 Dec; 289(6):F1262-72. Kim YH, Verlander JW, Matthews SW, Kurtz I, Shin W, Weiner ID, Everett LA, Green ED, Nielsen S, Wall SM. PMID: 16144965.
      View in: PubMed   Mentions: 26     Fields:    Translation:Animals
    97. Metabolic acidosis of CKD: diagnosis, clinical characteristics, and treatment. Am J Kidney Dis. 2005 Jun; 45(6):978-93. Kraut JA, Kurtz I. PMID: 15957126.
      View in: PubMed   Mentions: 95     Fields:    Translation:Humans
    98. Critical amino acid residues involved in the electrogenic sodium-bicarbonate cotransporter kNBC1-mediated transport. J Physiol. 2005 Jun 15; 565(Pt 3):717-30. Abuladze N, Azimov R, Newman D, Sassani P, Liu W, Tatishchev S, Pushkin A, Kurtz I. PMID: 15817634; PMCID: PMC1464572.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCells
    99. An analysis of current quantitative approaches to the treatment of severe symptomatic SIADH with intravenous saline therapy. Clin Exp Nephrol. 2005 Mar; 9(1):1-4. Nguyen MK, Kurtz I. PMID: 15830266.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    100. A new formula for predicting alterations in plasma sodium concentration in peritoneal dialysis. Am J Physiol Renal Physiol. 2005 Jun; 288(6):F1113-7. Nguyen MK, Kurtz I. PMID: 15625082.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    101. Derivation of a new formula for calculating urinary electrolyte-free water clearance based on the Edelman equation. Am J Physiol Renal Physiol. 2005 Jan; 288(1):F1-7. Nguyen MK, Kurtz I. PMID: 15383402.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    102. New insights into the pathophysiology of the dysnatremias: a quantitative analysis. Am J Physiol Renal Physiol. 2004 Aug; 287(2):F172-80. Nguyen MK, Kurtz I. PMID: 15271684.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    103. Molecular mechanism of kNBC1-carbonic anhydrase II interaction in proximal tubule cells. J Physiol. 2004 Aug 15; 559(Pt 1):55-65. Pushkin A, Abuladze N, Gross E, Newman D, Tatishchev S, Lee I, Fedotoff O, Bondar G, Azimov R, Ngyuen M, Kurtz I. PMID: 15218065; PMCID: PMC1665076.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    104. Role of potassium in hypokalemia-induced hyponatremia: lessons learned from the Edelman equation. Clin Exp Nephrol. 2004 Jun; 8(2):98-102. Nguyen MK, Kurtz I. PMID: 15235925.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    105. Expression and localization of rat NBC4c in liver and renal uroepithelium. Am J Physiol Cell Physiol. 2004 Sep; 287(3):C781-9. Abuladze N, Pushkin A, Tatishchev S, Newman D, Sassani P, Kurtz I. PMID: 15151908.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    106. Analysis of current formulas used for treatment of the dysnatremias. Clin Exp Nephrol. 2004 Mar; 8(1):12-6. Nguyen MK, Kurtz I. PMID: 15067511.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    107. Determinants of plasma water sodium concentration as reflected in the Edelman equation: role of osmotic and Gibbs-Donnan equilibrium. Am J Physiol Renal Physiol. 2004 May; 286(5):F828-37. Nguyen MK, Kurtz I. PMID: 15075178.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    108. Molecular mechanisms of electrogenic sodium bicarbonate cotransport: structural and equilibrium thermodynamic considerations. J Membr Biol. 2004 Jan 15; 197(2):77-90. Kurtz I, Petrasek D, Tatishchev S. PMID: 15014910.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    109. Structural characterization, tissue distribution, and functional expression of murine aminoacylase III. Am J Physiol Cell Physiol. 2004 Apr; 286(4):C848-56. Pushkin A, Carpenito G, Abuladze N, Newman D, Tsuprun V, Ryazantsev S, Motemoturu S, Sassani P, Solovieva N, Dukkipati R, Kurtz I. PMID: 14656720.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    110. Mapping blood pressure loci in (A/J x B6)F2 mice. Physiol Genomics. 2003 Nov 11; 15(3):236-42. Woo DD, Kurtz I. PMID: 14612590.
      View in: PubMed   Mentions: 11     Fields:    Translation:Animals
    111. An unusual case of pseudohyperkalaemia. Nephrol Dial Transplant. 2003 Aug; 18(8):1657-9. Nguyen MK, Kurtz I. PMID: 12897110.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    112. Are the total exchangeable sodium, total exchangeable potassium and total body water the only determinants of the plasma water sodium concentration? Nephrol Dial Transplant. 2003 Jul; 18(7):1266-71. Nguyen MK, Kurtz I. PMID: 12808160.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    113. Blindness and auditory impairment caused by loss of the sodium bicarbonate cotransporter NBC3. Nat Genet. 2003 Jul; 34(3):313-9. Bok D, Galbraith G, Lopez I, Woodruff M, Nusinowitz S, BeltrandelRio H, Huang W, Zhao S, Geske R, Montgomery C, Van Sligtenhorst I, Friddle C, Platt K, Sparks MJ, Pushkin A, Abuladze N, Ishiyama A, Dukkipati R, Liu W, Kurtz I. PMID: 12808454.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    114. A simple quantitative approach to analyzing the generation of the dysnatremias. Clin Exp Nephrol. 2003 Jun; 7(2):138-43. Kurtz I, Nguyen MK. PMID: 14586732.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    115. A new quantitative approach to the treatment of the dysnatremias. Clin Exp Nephrol. 2003 Jun; 7(2):125-37. Nguyen MK, Kurtz I. PMID: 14586731.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    116. Molecular pathogenesis of nephrogenic diabetes insipidus. Clin Exp Nephrol. 2003 Mar; 7(1):9-17. Nguyen MK, Nielsen S, Kurtz I. PMID: 14586738.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    117. Identification of membrane topography of the electrogenic sodium bicarbonate cotransporter pNBC1 by in vitro transcription/translation. Biochemistry. 2003 Jan 28; 42(3):755-65. Tatishchev S, Abuladze N, Pushkin A, Newman D, Liu W, Weeks D, Sachs G, Kurtz I. PMID: 12534288.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    118. Green urine in a critically ill patient. Am J Kidney Dis. 2002 Apr; 39(4):E20. Carpenito G, Kurtz I. PMID: 11920362.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    119. Chronic metabolic acidosis upregulates rat kidney Na-HCO cotransporters NBCn1 and NBC3 but not NBC1. Am J Physiol Renal Physiol. 2002 Feb; 282(2):F341-51. Kwon TH, Fulton C, Wang W, Kurtz I, Frøkiaer J, Aalkjaer C, Nielsen S. PMID: 11788449.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    120. Functional characterization of NBC4: a new electrogenic sodium-bicarbonate cotransporter. Am J Physiol Cell Physiol. 2002 Feb; 282(2):C408-16. Sassani P, Pushkin A, Gross E, Gomer A, Abuladze N, Dukkipati R, Carpenito G, Kurtz I. PMID: 11788353.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
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