Publications:
A selected list of publications:
Parks Brian W, Nam Elizabeth, Org Elin, Kostem Emrah, Norheim Frode, Hui Simon T, Pan Calvin, Civelek Mete, Rau Christoph D, Bennett Brian J, Mehrabian Margarete, Ursell Luke K, He Aiqing, Castellani Lawrence W, Zinker Bradley, Kirby Mark, Drake Thomas A, Drevon Christian A, Knight Rob, Gargalovic Peter, Kirchgessner Todd, Eskin Eleazar, Lusis Aldons J
Genetic control of obesity and gut microbiota composition in response
to high-fat, high-sucrose diet in mice
Cell metabolism,
2013; 17(1):
141-52.
Lagarrigue Sandrine, Hormozdiari Farhad, Martin Lisa J, Lecerf Frédéric, Hasin Yehudit, Rau Christoph, Hagopian Raffi, Xiao Yu, Yan Jun, Drake Thomas A, Ghazalpour Anatole, Eskin Eleazar, Lusis Aldons J
Limited RNA editing in exons of mouse liver and adipose
Genetics,
2013; 193(4):
1107-15.
Martin Lisa J, Lau Edward, Singh Harpreet, Vergnes Laurent, Tarling Elizabeth J, Mehrabian Margarete, Mungrue Imran, Xiao Sheila, Shih Diana, Castellani Lawrence, Ping Peipei, Reue Karen, Stefani Enrico, Drake Thomas A, Bostrom Kristina, Lusis Aldons J
Response to Pomozi et al's research commentary
Circulation research,
2013; 112(11):
e152-3.
Martin Lisa J, Lau Edward, Singh Harpreet, Vergnes Laurent, Tarling Elizabeth J, Mehrabian Margarete, Mungrue Imran, Xiao Sheila, Shih Diana, Castellani Lawrence, Ping Peipei, Reue Karen, Stefani Enrico, Drake Thomas A, Bostrom Kristina, Lusis Aldons J
ABCC6 localizes to the mitochondria-associated membrane
Circulation research,
2012; 111(5):
516-20.
Ghazalpour Anatole, Rau Christoph D, Farber Charles R, Bennett Brian J, Orozco Luz D, van Nas Atila, Pan Calvin, Allayee Hooman, Beaven Simon W, Civelek Mete, Davis Richard C, Drake Thomas A, Friedman Rick A, Furlotte Nick, Hui Simon T, Jentsch J David, Kostem Emrah, Kang Hyun Min, Kang Eun Yong, Joo Jong Wha, Korshunov Vyacheslav A, Laughlin Rick E, Martin Lisa J, Ohmen Jeffrey D, Parks Brian W, Pellegrini Matteo, Reue Karen, Smith Desmond J, Tetradis Sotirios, Wang Jessica, Wang Yibin, Weiss James N, Kirchgessner Todd, Gargalovic Peter S, Eskin Eleazar, Lusis Aldons J, LeBoeuf Renée C
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable
for analysis of complex genetic traits
Mammalian genome : official journal of the International Mammalian Genome Society,
2012; 23(9-10):
680-92.
Mungrue Imran N, Zhao Peng, Yao Yucheng, Meng Haijin, Rau Christoph, Havel Jocelyn V, Gorgels Theo G M F, Bergen Arthur A B, MacLellan W Robb, Drake Thomas A, Boström Kristina I, Lusis Aldons J
Abcc6 deficiency causes increased infarct size and apoptosis in a
mouse cardiac ischemia-reperfusion model
Arteriosclerosis, thrombosis, and vascular biology,
2011; 31(12):
2806-12.
Farber Charles R, Bennett Brian J, Orozco Luz, Zou Wei, Lira Ana, Kostem Emrah, Kang Hyun Min, Furlotte Nicholas, Berberyan Ani, Ghazalpour Anatole, Suwanwela Jaijam, Drake Thomas A, Eskin Eleazar, Wang Q Tian, Teitelbaum Steven L, Lusis Aldons J
Mouse genome-wide association and systems genetics identify Asxl2 as a
regulator of bone mineral density and osteoclastogenesis
PLoS genetics,
2011; 7(4):
e1002038.
Bennett Brian J, Farber Charles R, Orozco Luz, Kang Hyun Min, Ghazalpour Anatole, Siemers Nathan, Neubauer Michael, Neuhaus Isaac, Yordanova Roumyana, Guan Bo, Truong Amy, Yang Wen-pin, He Aiqing, Kayne Paul, Gargalovic Peter, Kirchgessner Todd, Pan Calvin, Castellani Lawrence W, Kostem Emrah, Furlotte Nicholas, Drake Thomas A, Eskin Eleazar, Lusis Aldons J
A high-resolution association mapping panel for the dissection of
complex traits in mice
Genome research,
2010; 20(2):
281-90.
Farber Charles R, van Nas Atila, Ghazalpour Anatole, Aten Jason E, Doss Sudheer, Sos Brandon, Schadt Eric E, Ingram-Drake Leslie, Davis Richard C, Horvath Steve, Smith Desmond J, Drake Thomas A, Lusis Aldons J
An integrative genetics approach to identify candidate genes
regulating BMD: combining linkage, gene expression, and association
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research,
2009; 24(1):
105-16.
Wang Susanna S, Martin Lisa J, Schadt Eric E, Meng Haijin, Wang Xuping, Zhao Wei, Ingram-Drake Leslie, Nebohacova Martina, Mehrabian Margarete, Drake Thomas A, Lusis Aldons J
Disruption of the aortic elastic lamina and medial calcification share
genetic determinants in mice
Circulation. Cardiovascular genetics,
2009; 2(6):
573-82.
van Nas Atila, Guhathakurta Debraj, Wang Susanna S, Yehya Nadir, Horvath Steve, Zhang Bin, Ingram-Drake Leslie, Chaudhuri Gautam, Schadt Eric E, Drake Thomas A, Arnold Arthur P, Lusis Aldons J
Elucidating the role of gonadal hormones in sexually dimorphic gene
coexpression networks
Endocrinology,
2009; 150(3):
1235-49.
Yang Xia, Deignan Joshua L, Qi Hongxiu, Zhu Jun, Qian Su, Zhong Judy, Torosyan Gevork, Majid Sana, Falkard Brie, Kleinhanz Robert R, Karlsson Jenny, Castellani Lawrence W, Mumick Sheena, Wang Kai, Xie Tao, Coon Michael, Zhang Chunsheng, Estrada-Smith Daria, Farber Charles R, Wang Susanna S, van Nas Atila, Ghazalpour Anatole, Zhang Bin, Macneil Douglas J, Lamb John R, Dipple Katrina M, Reitman Marc L, Mehrabian Margarete, Lum Pek Y, Schadt Eric E, Lusis Aldons J, Drake Thomas A
Validation of candidate causal genes for obesity that affect shared
metabolic pathways and networks
Nature genetics,
2009; 41(4):
415-23.
Ghazalpour Anatole, Doss Sudheer, Kang Hyun, Farber Charles, Wen Ping-Zi, Brozell Alec, Castellanos Ruth, Eskin Eleazar, Smith Desmond J, Drake Thomas A, Lusis Aldons J
High-resolution mapping of gene expression using association in an
outbred mouse stock
PLoS genetics,
2008; 4(8):
e1000149.
Schadt Eric E, Molony Cliona, Chudin Eugene, Hao Ke, Yang Xia, Lum Pek Y, Kasarskis Andrew, Zhang Bin, Wang Susanna, Suver Christine, Zhu Jun, Millstein Joshua, Sieberts Solveig, Lamb John, GuhaThakurta Debraj, Derry Jonathan, Storey John D, Avila-Campillo Iliana, Kruger Mark J, Johnson Jason M, Rohl Carol A, van Nas Atila, Mehrabian Margarete, Drake Thomas A, Lusis Aldons J, Smith Ryan C, Guengerich F Peter, Strom Stephen C, Schuetz Erin, Rushmore Thomas H, Ulrich Roger
Mapping the genetic architecture of gene expression in human liver
PLoS biology,
2008; 6(5):
e107.
Chen Yanqing, Zhu Jun, Lum Pek Yee, Yang Xia, Pinto Shirly, MacNeil Douglas J, Zhang Chunsheng, Lamb John, Edwards Stephen, Sieberts Solveig K, Leonardson Amy, Castellini Lawrence W, Wang Susanna, Champy Marie-France, Zhang Bin, Emilsson Valur, Doss Sudheer, Ghazalpour Anatole, Horvath Steve, Drake Thomas A, Lusis Aldons J, Schadt Eric E
Variations in DNA elucidate molecular networks that cause disease
Nature,
2008; 452(7186):
429-35.
Drake Thomas A, Braun Jonathan, Marchevsky Alberto, Kohane Isaac S, Fletcher Christopher, Chueh Henry, Beckwith Bruce, Berkowicz David, Kuo Frank, Zeng Qing T, Balis Ulysses, Holzbach Ana, McMurry Andrew, Gee Connie E, McDonald Clement J, Schadow Gunther, Davis Mary, Hattab Eyas M, Blevins Lonnie, Hook John, Becich Michael, Crowley Rebecca S, Taube Sheila E, Berman Jules, Berman Jules
A system for sharing routine surgical pathology specimens across
institutions: the Shared Pathology Informatics Network
Human pathology,
2007; 38(8):
1212-25.
Wang Susanna S, Shi Weibin, Wang Xuping, Velky Leandra, Greenlee Sarah, Wang Min T, Drake Thomas A, Lusis Aldons J
Mapping, genetic isolation, and characterization of genetic loci that
determine resistance to atherosclerosis in C3H mice
Arteriosclerosis, thrombosis, and vascular biology,
2007; 27(12):
2671-6.
Ghazalpour Anatole, Doss Sudheer, Zhang Bin, Wang Susanna, Plaisier Christopher, Castellanos Ruth, Brozell Alec, Schadt Eric E, Drake Thomas A, Lusis Aldons J, Horvath Steve
Integrating genetic and network analysis to characterize genes related
to mouse weight
PLoS genetics,
2006; 2(8):
e130.
Schadt Eric E, Lamb John, Yang Xia, Zhu Jun, Edwards Steve, Guhathakurta Debraj, Sieberts Solveig K, Monks Stephanie, Reitman Marc, Zhang Chunsheng, Lum Pek Yee, Leonardson Amy, Thieringer Rolf, Metzger Joseph M, Yang Liming, Castle John, Zhu Haoyuan, Kash Shera F, Drake Thomas A, Sachs Alan, Lusis Aldons J
An integrative genomics approach to infer causal associations between
gene expression and disease
Nature genetics,
2005; 37(7):
710-7.
Schadt, EE Lamb, J Yang, X Zhu, J Edwards, S Guhathakurta, D Sieberts, SK Monks, S Reitman, M Zhang, C Lum, PY Leonardson, A Thieringer, R Metzger, JM Yang, L Castle, J Zhu, H Kash, SF Drake, TA Sachs, A Lusis, AJ
An integrative genomics approach to infer causal associations between gene expression and disease
Nature genetics. ,
2005; 37(7):
710-7.
Mehrabian Margarete, Allayee Hooman, Stockton Jirina, Lum Pek Yee, Drake Thomas A, Castellani Lawrence W, Suh Michael, Armour Christopher, Edwards Stephen, Lamb John, Lusis Aldons J, Schadt Eric E
Integrating genotypic and expression data in a segregating mouse
population to identify 5-lipoxygenase as a susceptibility gene for
obesity and bone traits
Nature genetics,
2005; 37(11):
1224-33.
Ghazalpour, A Doss, S Yang, X Aten, J Toomey, EM Van Nas, A Wang, S Drake, TA Lusis, AJ
Thematic review series: The pathogenesis of atherosclerosis. Toward a biological network for atherosclerosis
Journal of lipid research. ,
2004; 45(10):
1793-805.
Shi Weibin, Brown Morry D, Wang Xuping, Wong Jack, Kallmes David F, Matsumoto Alan H, Helm Gregory A, Drake Thomas A, Lusis Aldons J
Genetic backgrounds but not sizes of atherosclerotic lesions determine
medial destruction in the aortic root of apolipoprotein E-deficient
mice
Arteriosclerosis, thrombosis, and vascular biology,
2003; 23(10):
1901-6.
Schadt, EE Monks, SA Drake, TA Lusis, AJ Che, N Colinayo, V Ruff, TG Milligan, SB Lamb, JR Cavet, G Linsley, PS Mao, M Stoughton, RB Friend, SH
Genetics of gene expression surveyed in maize, mouse and man
Nature. ,
2003; 422(6929):
297-302.
Schadt Eric E, Monks Stephanie A, Drake Thomas A, Lusis Aldons J, Che Nam, Colinayo Veronica, Ruff Thomas G, Milligan Stephen B, Lamb John R, Cavet Guy, Linsley Peter S, Mao Mao, Stoughton Roland B, Friend Stephen H
Genetics of gene expression surveyed in maize, mouse and man
Nature,
2003; 422(6929):
297-302.
Colinayo Veronica V, Qiao Jian-Hua, Demant Peter, Krass Kelly, Lusis Aldons J, Drake Thomas A
Genetic characterization of the Dyscalc locus
Mammalian genome : official journal of the International Mammalian Genome Society,
2002; 13(6):
283-8.