George Bartzokis, M.D.


Work Titles
UCLA Professor, Psychiatry and Biobehavioral Sciences Member, Brain Research Institute Member, Jane and Terry Semel Institute for Neuroscience and Human Behavior Member, Outpatient Mood Disorders Program
Education:
Degrees:
M.D., Yale University School of Medicine, 1983
Fellowship:
1987 - 1990 UCLA Neuropsychiatric Hospital
Internship:
1983 - 1984 UCLA Neuropsychiatric Hospital
Certifications:
Certifications:
1994 American Board of Psychiatry and Neurology
1990 American Board of Psychiatry and Neurology

Contact Information:

Work Email Address:

gbar@ucla.edu


Work Phone Number:

(310) 206-3207

Mailing Address:

300 UCLA Medical Plaza
Suite 2200
Los Angeles, CA 90095

Suite 2200
Los Angeles,, CA 90095


Publications:

A selected list of publications:

Bartzokis George, Lu Po H, Amar Chetan P, Raven Erika P, Detore Nicole R, Altshuler Lori L, Mintz Jim, Ventura Joseph, Casaus Laurie R, Luo John S, Subotnik Kenneth L, Nuechterlein Keith H   Long acting injection versus oral risperidone in first-episode schizophrenia: Differential impact on white matter myelination trajectory Schizophrenia research, 2011; 132(1): 35-41.
Bartzokis George   Neuroglialpharmacology: white matter pathophysiologies and psychiatric treatments Frontiers in bioscience : a journal and virtual library, 2011; 17(1): 2695-733.
Tishler Todd A, Raven Erika P, Lu Po H, Altshuler Lori L, Bartzokis George   Premenopausal hysterectomy is associated with increased brain ferritin iron Neurobiology of aging, 2011; 132(1): .
Bartzokis George, Lu Po H, Tingus Kathleen, Peters Douglas G, Amar Chetan P, Tishler Todd A, Finn J Paul, Villablanca Pablo, Altshuler Lori L, Mintz Jim, Neely Elizabeth, Connor James R   Gender and iron genes may modify associations between brain iron and memory in healthy aging Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011; 36(7): 1375-84.
Lu Po H, Thompson Paul M, Leow Alex, Lee Grace J, Lee Agatha, Yanovsky Igor, Parikshak Neelroop, Khoo Theresa, Wu Stephanie, Geschwind Daniel, Bartzokis George   Apolipoprotein E Genotype is Associated with Temporal and Hippocampal Atrophy Rates in Healthy Elderly Adults: A Tensor-Based Morphometry Study Journal of Alzheimer's disease : JAD, 2011; 23(3): 433-42.
Bartzokis George, Lu Po H, Tingus Kathleen, Mendez Mario F, Richard Aurore, Peters Douglas G, Oluwadara Bolanle, Barrall Katherine A, Finn J Paul, Villablanca Pablo, Thompson Paul M, Mintz Jim   Lifespan trajectory of myelin integrity and maximum motor speed Neurobiology of aging, 2010; 31(9): 1554-62.
Altshuler Lori L, Abulseoud Osama A, Foland-Ross Lara, Bartzokis George, Chang Sean, Mintz Jim, Hellemann Gerhard, Vinters Harry V   Amygdala astrocyte reduction in subjects with major depressive disorder but not bipolar disorder Bipolar disorders, 2010; 12(5): 541-9.
Shineman Diana W, Salthouse Timothy A, Launer Lenore J, Hof Patrick R, Bartzokis George, Kleiman Robin, Luine Victoria, Buccafusco Jerry J, Small Gary W, Aisen Paul S, Lowe David A, Fillit Howard M   Therapeutics for cognitive aging Annals of the New York Academy of Sciences, 2010; 1191 Suppl 1(5): E1-15.
Bartzokis George, Lu Po H, Tishler Todd A, Peters Douglas G, Kosenko Anastasia, Barrall Katherine A, Finn J Paul, Villablanca Pablo, Laub Gerhard, Altshuler Lori L, Geschwind Daniel H, Mintz Jim, Neely Elizabeth, Connor James R   Prevalent iron metabolism gene variants associated with increased brain ferritin iron in healthy older men Journal of Alzheimer's disease : JAD, 2010; 20(1): 333-41.
Tobias Marc C, O'Neill Joseph, Hudkins Matthew, Bartzokis George, Dean Andrew C, London Edythe D   White-matter abnormalities in brain during early abstinence from methamphetamine abuse Psychopharmacology, 2010; 209(1): 13-24.
Bartzokis   Alzheimer's disease as homeostatic responses to age-related myelin breakdown Neurobiology of aging, 2009; .
Bartzokis George, Lu Po H, Stewart Stephanie B, Oluwadara Bolanle, Lucas Andrew J, Pantages Joanna, Pratt Erika, Sherin Jonathan E, Altshuler Lori L, Mintz Jim, Gitlin Michael J, Subotnik Kenneth L, Nuechterlein Keith H   In vivo evidence of differential impact of typical and atypical antipsychotics on intracortical myelin in adults with schizophrenia Schizophrenia research, 2009; 113(2-3): 322-31.
Thompson Paul M, Bartzokis George, Hayashi Kiralee M, Klunder Andrea D, Lu Po H, Edwards Nancy, Hong Michael S, Yu Michael, Geaga Jennifer A, Toga Arthur W, Charles Cecil, Perkins Diana O, McEvoy Joseph, Hamer Robert M, Tohen Mauricio, Tollefson Gary D, Lieberman Jeffrey A, Lieberman Jeffrey A   Time-lapse mapping of cortical changes in schizophrenia with different treatments Cerebral cortex (New York, N.Y. : 1991), 2009; 19(5): 1107-23.
Berman Steven, O'Neill Joseph, Fears Scott, Bartzokis George, London Edythe D   Abuse of amphetamines and structural abnormalities in the brain Annals of the New York Academy of Sciences, 2008; 1141(5): 195-220.
Teng Edmond, Ringman John M, Ross Leslie K, Mulnard Ruth A, Dick Malcolm B, Bartzokis George, Davies Helen D, Galasko Douglas, Hewett Linda, Mungas Dan, Reed Bruce R, Schneider Lon S, Segal-Gidan Freddi, Yaffe Kristine, Cummings Jeffrey L, Cummings Jeffrey L   Diagnosing depression in Alzheimer disease with the national institute of mental health provisional criteria The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2008; 16(6): 469-77.
Jack Clifford R, Bernstein Matt A, Fox Nick C, Thompson Paul, Alexander Gene, Harvey Danielle, Borowski Bret, Britson Paula J, L Whitwell Jennifer, Ward Chadwick, Dale Anders M, Felmlee Joel P, Gunter Jeffrey L, Hill Derek L G, Killiany Ron, Schuff Norbert, Fox-Bosetti Sabrina, Lin Chen, Studholme Colin, DeCarli Charles S, Krueger Gunnar, Ward Heidi A, Metzger Gregory J, Scott Katherine T, Mallozzi Richard, Blezek Daniel, Levy Joshua, Debbins Josef P, Fleisher Adam S, Albert Marilyn, Green Robert, Bartzokis George, Glover Gary, Mugler John, Weiner Michael W   The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods Journal of magnetic resonance imaging : JMRI, 2008; 27(4): 685-91.
Bartzokis George, Lu Po H, Geschwind Daniel H, Tingus Kathleen, Huang Danny, Mendez Mario F, Edwards Nancy, Mintz Jim   Apolipoprotein E affects both myelin breakdown and cognition: implications for age-related trajectories of decline into dementia Biological psychiatry, 2007; 62(12): 1380-7.
Bartzokis George, Lu Po H, Tishler Todd A, Fong Sophia M, Oluwadara Bolanle, Finn J Paul, Huang Danny, Bordelon Yvette, Mintz Jim, Perlman Susan   Myelin breakdown and iron changes in Huntington's disease: pathogenesis and treatment implications Neurochemical research, 2007; 32(10): 1655-64.
Bartzokis George   Acetylcholinesterase inhibitors may improve myelin integrity Biological psychiatry, 2007; 62(4): 294-301.
Bartzokis George, Lu Po H, Nuechterlein Keith H, Gitlin Michael, Doi Clarissa, Edwards Nancy, Lieu Christopher, Altshuler Lori L, Mintz Jim   Differential effects of typical and atypical antipsychotics on brain myelination in schizophrenia Schizophrenia research, 2007; 93(1-3): 13-22.
Ringman John M, O'Neill Joseph, Geschwind Daniel, Medina Luis, Apostolova Liana G, Rodriguez Yaneth, Schaffer Barbara, Varpetian Arousiak, Tseng Benjamin, Ortiz Freddy, Fitten Jaime, Cummings Jeffrey L, Bartzokis George   Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer's disease mutations Brain : a journal of neurology, 2007; 130(Pt 7): 1767-76.
Bartzokis George, Lu Po H, Mintz Jim   Human brain myelination and amyloid beta deposition in Alzheimer's disease Alzheimer's & dementia : the journal of the Alzheimer's Association, 2007; 3(2): 122-5.
Bartzokis George, Tishler Todd A, Lu Po H, Villablanca Pablo, Altshuler Lori L, Carter Michele, Huang Danny, Edwards Nancy, Mintz Jim   Brain ferritin iron may influence age- and gender-related risks of neurodegeneration Neurobiology of aging, 2007; 28(3): 414-23.
Ardekani Siamak, Kumar Anand, Bartzokis George, Sinha Usha   Exploratory voxel-based analysis of diffusion indices and hemispheric asymmetry in normal aging Magnetic resonance imaging, 2007; 25(2): 154-67.
Venneman Sandy, Leuchter Andrew, Bartzokis George, Beckson Mace, Simon Sara L, Schaefer Melodie, Rawson Richard, Newton Tom, Cook Ian A, Uijtdehaage Sebastian, Ling Walter   Variation in neurophysiological function and evidence of quantitative electroencephalogram discordance: predicting cocaine-dependent treatment attrition The Journal of neuropsychiatry and clinical neurosciences, 2006; 18(2): 208-16.
Bartzokis George, Lu Po H, Geschwind Daniel H, Edwards Nancy, Mintz Jim, Cummings Jeffrey L   Apolipoprotein E genotype and age-related myelin breakdown in healthy individuals: implications for cognitive decline and dementia Archives of general psychiatry, 2006; 63(1): 63-72.
Goldstein Iris B, Bartzokis George, Guthrie Donald, Shapiro David   Ambulatory blood pressure and the brain: a 5-year follow-up Neurology, 2005; 64(11): 1846-52.
Bartzokis George   BRAIN MYELINATION IN PREVALENT NEUROPSYCHIATRIC DEVELOPMENTAL DISORDERS: PRIMARY AND COMORBID ADDICTION Adolescent psychiatry, 2005; 29(6): 55-96.
Altshuler Lori, Bookheimer Susan, Proenza Manuel A, Townsend Jennifer, Sabb Fred, Firestine Ann, Bartzokis George, Mintz Jim, Mazziotta John, Cohen Mark S   Increased amygdala activation during mania: a functional magnetic resonance imaging study The American journal of psychiatry, 2005; 162(6): 1211-3.
Bartzokis George, Altshuler Lori   Reduced intracortical myelination in schizophrenia The American journal of psychiatry, 2005; 162(6): 1229-30.
Bartzokis George, Lu Po H, Turner Jana, Mintz Jim, Saunders C Scott   Adjunctive risperidone in the treatment of chronic combat-related posttraumatic stress disorder Biological psychiatry, 2005; 57(5): 474-9.
Bartzokis George, Lu Po H, Mintz Jim   Quantifying age-related myelin breakdown with MRI: novel therapeutic targets for preventing cognitive decline and Alzheimer's disease Journal of Alzheimer's disease : JAD, 2004; 6(6 Suppl): S53-9.
Bartzokis George, Sultzer David, Lu Po H, Nuechterlein Keith H, Mintz Jim, Cummings Jeffrey L   Heterogeneous age-related breakdown of white matter structural integrity: implications for cortical "disconnection" in aging and Alzheimer's disease Neurobiology of aging, 2004; 25(7): 843-51.
Bartzokis George, Tishler Todd A, Shin Il-Seon, Lu Po H, Cummings Jeffrey L   Brain ferritin iron as a risk factor for age at onset in neurodegenerative diseases Annals of the New York Academy of Sciences, 2004; 1012(7): 224-36.
Bartzokis George, Beckson Mace, Lu Po H, Edwards Nancy, Rapoport Ruth, Bridge Peter, Mintz Jim   Cortical gray matter volumes are associated with subjective responses to cocaine infusion The American journal on addictions / American Academy of Psychiatrists in Alcoholism and Addictions, 2004; 13(1): 64-73.
Bartzokis George   Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease Neurobiology of aging, 2004; 25(1): 5-18; author reply 49-62.
Bartzokis, G   Age-related myelin breakdown: a developmental model of cognitive decline and Alzheimer's disease Neurobiology of aging. , 2004; 25(1): 5-18; author reply 49-62.
Brody Arthur L, Mandelkern Mark A, Jarvik Murray E, Lee Grace S, Smith Erlyn C, Huang Joe C, Bota Robert G, Bartzokis George, London Edythe D   Differences between smokers and nonsmokers in regional gray matter volumes and densities Biological psychiatry, 2004; 55(1): 77-84.
Subotnik Kenneth L, Bartzokis George, Green Michael F, Nuechterlein Keith H   Neuroanatomical correlates of formal thought disorder in schizophrenia Cognitive neuropsychiatry, 2003; 8(2): 81-8.
Bartzokis George, Nuechterlein Keith H, Lu Po H, Gitlin Michael, Rogers Steven, Mintz Jim   Dysregulated brain development in adult men with schizophrenia: a magnetic resonance imaging study Biological psychiatry, 2003; 53(5): 412-21.
Bartzokis George, Cummings Jeffrey L, Sultzer David, Henderson Victor W, Nuechterlein Keith H, Mintz Jim   White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study Archives of neurology, 2003; 60(3): 393-8.
Bartzokis, G Cummings, JL Sultzer, D Henderson, VW Nuechterlein, KH Mintz, J   White matter structural integrity in healthy aging adults and patients with Alzheimer disease: a magnetic resonance imaging study Archives of neurology. , 2003; 60(3): 393-8.
Bartzokis George   Schizophrenia: breakdown in the well-regulated lifelong process of brain development and maturation Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2002; 27(4): 672-83.
Goldstein Iris B, Bartzokis George, Guthrie Donald, Shapiro David   Ambulatory blood pressure and brain atrophy in the healthy elderly Neurology, 2002; 59(5): 713-9.
Bartzokis George, Beckson Mace, Lu Po H, Edwards Nancy, Bridge Peter, Mintz Jim   Brain maturation may be arrested in chronic cocaine addicts Biological psychiatry, 2002; 51(8): 605-11.
Bartzokis, G Beckson, M Lu, PH Nuechterlein, KH Edwards, N Mintz, J   Age-related changes in frontal and temporal lobe volumes in men: a magnetic resonance imaging study Archives of general psychiatry. , 2001; 58(5): 461-5.

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