Michael Irwin, M.D.


Work Titles
CTSI Co-Leader, Clinical Immunology Research Laboratory (CIRL) Co-Leader, Pilot and Collaborative Translational Clinical Studies Program
UCLA Director, Cousins Center for Psychoneuroimmunology Director, Mindful Awareness Research Center Professor, Psychology Professor, Psychiatry and Biobehavioral Sciences
Education:
Degrees:
M.D., University of California, San Diego, 1976 - 1981
B.A., University of Pennsylvania, 1972 - 1976
Internship:
1981 - 1982 University of California, San Diego
Residency:
1982 - 1985 University of California, Los Angeles
Certifications:
Certifications:
1987 American Board of Psychiatry and Neurology

Contact Information:

Work Email Address:

mirwin1@ucla.edu


Website:

Home Page
Home Page

Work Phone Number:

(310) 825-8281

Work Address:

Medical Plaza 300, Room 3109
Campus - 707624
Los Angeles, CA 90095


Detailed Biography:

Dr. Michael R. Irwin is Cousins Distinguished Professor of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA; Distinguished Professor of Psychology, UCLA College of Letters and Sciences; Director, Cousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience; Director of the Mindful Awareness Research Center. Michael R. Irwin is one of the world’s foremost experts on the psychoneuroimmunological pathways by which psychosocial and behavioral factors influence health and disease. He is the Norman Cousins Distinguished Professor of Psychiatry and Biobehavioral Science at the UCLA Geffen School of Medicine, Director of the Cousins Center for Psychoneuroimmunology at the UCLA Semel Institute, Director of the Mindful Awareness Research Center at the UCLA Semel Institute, and Director of the Center’s Inflammatory Biology Core. Dr. Irwin pioneered basic studies to show that activation of receptor dependent mechanisms in the brain (e.g., corticotropin releasing hormone) play a key role in the integration of the HPA, autonomic, and immune responses to stress. His clinical translational studies were among the first to demonstrate that b-adrenergic receptor mechanisms steered a reduction in anti-viral immunity and an increase inflammatory responses, and the role of these molecular pathways on infectious- and inflammatory disease pathogenesis in older adults, and in patients with depression, insomnia, cardiovascular disease, cancer, rheumatoid arthritis, and alcohol- and cocaine use disorders. His ongoing work is focused on the reciprocal interactions between the immune- and central nervous systems, and the role of sleep disturbance on the molecular and cellular inflammatory signaling pathways that influence depression- and physical health risk with a focus on cancer survivors and older adults. Dr. Irwin’s research has broadly integrated data from laboratory animal studies, epidemiological studies, clinical naturalistic history- and prospective studies, experimental studies, and randomized controlled trials that have employed both behavioral- and mind-body approaches, which has resulted in publication of over 300 research articles and several books. Together, his research has been supported continuously for over 25 years by his PI leadership of over 25 R01 type awards from the National Institute of Aging, National Cancer Institute, National Heart Lung and Blood Disorders Institute, National Institute of Alcoholism and Alcohol Abuse, National Institute of Arthritis and Musculoskeletal Disorders, National Institute of Drug Abuse, National Center for Complementary and Alternative Medicine (NCCAM), and the National Institute of Mental Health. Dr. Irwin is Past President of the Psychoneuroimmunology Research Society and of the Academy of Behavioral Medicine Research, and a Distinguished Fellow in the American Psychiatric Association and the American College of Psychiatrists. He was an Associate Editor of Brain, Behavior, and Immunity, serves on the Editorial Board of Psychosomatic Medicine and of Sleep. He is Chairperson of NIH-CSR Mechanisms of Emotions, Stress, and Health Study Section, and past appointments on the NIMH Mental Health and AIDS Initial Review Group and Advisory Council to the National Center for Complementary and Alternative Medicine. He has received multiple national and international awards, and was twice the recipient of the Faculty Research Mentor Award from the Department of Psychiatry and Biobehavioral Science at the David Geffen School of Medicine.

Publications:

Inagaki Tristen K, Ray Lara A, Irwin Michael R, Way Baldwin M, Eisenberger Naomi I   Opioids and social bonding: Naltrexone reduces feelings of social connection Social cognitive and affective neuroscience, 2016; .
Carroll Judith E, Cole Steven W, Seeman Teresa E, Breen Elizabeth C, Witarama Tuff, Arevalo Jesusa M G, Ma Jeffrey, Irwin Michael R   Partial sleep deprivation activates the DNA damage response (DDR) and the senescence-associated secretory phenotype (SASP) in aged adult humans Brain, behavior, and immunity, 2016; 51: 223-9.
Irwin Michael R, Bjurstrom Martin F, Olmstead Richard   Polysomnographic Measures of Sleep in Cocaine Dependence and Alcohol Dependence: Implications for Age-Related Loss of Slow Wave, Stage 3 Sleep Addiction (Abingdon, England), 2016; .
Inagaki Tristen K, Irwin Michael R, Eisenberger Naomi I   Blocking Opioids Attenuates Physical Warmth-Induced Feelings of Social Connection Emotion (Washington, D.C.), 2015; 47: .
Campo Rebecca A, Light Kathleen C, O'Connor Kathleen, Nakamura Yoshio, Lipschitz David, LaStayo Paul C, Pappas Lisa M, Boucher Kenneth M, Irwin Michael R, Hill Harry R, Martins Thomas B, Agarwal Neeraj, Kinney Anita Y   Blood pressure, salivary cortisol, and inflammatory cytokine outcomes in senior female cancer survivors enrolled in a tai chi chih randomized controlled trial Journal of cancer survivorship : research and practice, 2015; 9(1): 115-25.
Irwin Michael R, Olmstead Richard, Breen Elizabeth C, Witarama Tuff, Carrillo Carmen, Sadeghi Nina, Arevalo Jesusa M G, Ma Jeffrey, Nicassio Perry, Bootzin Richard, Cole Steve   Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late Life Insomnia: A Randomized Controlled Trial Biological psychiatry, 2015; 11(2): .
Doering Lynn V, McGuire Anthony, Eastwood Jo-Ann, Chen Belinda, Bodán Rebecca C, Czer Lawrence S, Irwin Michael R   Cognitive behavioral therapy for depression improves pain and perceived control in cardiac surgery patients European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology, 2015; 47: .
Muscatell Keely A, Dedovic Katarina, Slavich George M, Jarcho Michael R, Breen Elizabeth C, Bower Julienne E, Irwin Michael R, Eisenberger Naomi I   Greater amygdala activity and dorsomedial prefrontal-amygdala coupling are associated with enhanced inflammatory responses to stress Brain, behavior, and immunity, 2015; 43(2): 46-53.
Youngstedt Shawn D, Goff Eric E, Reynolds Alexandria M, Kripke Daniel F, Irwin Michael R, Bootzin Richard R, Khan Nidha, Jean-Louis Girardin   Has adult sleep duration declined over the last 50+ years? Sleep medicine reviews, 2015; 28(40): 65-81.
Choi Hanbyul, Irwin Michael R, Cho Hyong Jin   Impact of social isolation on behavioral health in elderly: Systematic review World journal of psychiatry, 2015; 5(4): 432-8.
Carroll Judith E, Seeman Teresa E, Olmstead Richard, Melendez Gerson, Sadakane Ryan, Bootzin Richard, Nicassio Perry, Irwin Michael R   Improved sleep quality in older adults with insomnia reduces biomarkers of disease risk: pilot results from a randomized controlled comparative efficacy trial Psychoneuroendocrinology, 2015; 55(7): 184-92.
Moieni Mona, Irwin Michael R, Jevtic Ivana, Breen Elizabeth C, Eisenberger Naomi I   Inflammation impairs social cognitive processing: A randomized controlled trial of endotoxin Brain, behavior, and immunity, 2015; 77(3): .
Patel Sunita K, Wong Andrew L, Wong F Lennie, Breen Elizabeth Crabb, Hurria Arti, Smith Mackenzie, Kinjo Christine, Paz I Benjamin, Kruper Laura, Somlo George, Mortimer Joanne E, Palomares Melanie R, Irwin Michael R, Bhatia Smita   Inflammatory Biomarkers, Comorbidity, and Neurocognition in Women With Newly Diagnosed Breast Cancer Journal of the National Cancer Institute, 2015; 107(8): .
Coccaro Emil F, Lee Royce, Breen Elizabeth C, Irwin Michael R   Inflammatory markers and chronic exposure to fluoxetine, divalproex, and placebo in intermittent explosive disorder Psychiatry research, 2015; 229(3): 844-9.
Carroll Judith E, Esquivel Stephanie, Goldberg Alyssa, Seeman Teresa E, Effros Rita B, Dock Jeffrey, Olmstead Richard, Breen Elizabeth C, Irwin Michael R   Insomnia and Telomere Length in Older Adults Sleep, 2015; 2016: .
Cho Hyong Jin, Irwin Michael R   Is Inflammation a Link Between Self-Reported Health and Infectious Disease Risk? Psychosomatic medicine, 2015; 77(9): 956-8.
Bower Julienne E, Irwin Michael R   Mind-body therapies and control of inflammatory biology: A descriptive review Brain, behavior, and immunity, 2015; 47: .
Black David S, O'Reilly Gillian A, Olmstead Richard, Breen Elizabeth C, Irwin Michael R   Mindfulness meditation and improvement in sleep quality and daytime impairment among older adults with sleep disturbances: a randomized clinical trial JAMA internal medicine, 2015; 175(4): 494-501.
Ormseth Sarah R, Draper Taylor L, Irwin Michael R, Weisman Michael H, Aréchiga Adam E, Hartoonian Narineh, Bui Thuy, Nicassio Perry M   Multidimensional Model of Disability and Role Functioning in Rheumatoid Arthritis Arthritis care & research, 2015; 67(12): 1686-92.
Compton Peggy, Griffis Charles, Breen Elizabeth Crabb, Torrington Matthew, Sadakane Ryan, Tefera Eshetu, Irwin Michael R   Opioid treatment of experimental pain activates nuclear factor-κB Journal of opioid management, 2015; 11(2): 115-25.
Bjurstrom Martin F, Irwin Michael R   Polysomnographic characteristics in nonmalignant chronic pain populations: A review of controlled studies Sleep medicine reviews, 2015; 55(7): .
Dzierzewski Joseph M, Song Yeonsu, Fung Constance H, Rodriguez Juan C, Jouldjian Stella, Alessi Cathy A, Breen Elizabeth C, Irwin Michael R, Martin Jennifer L   Self-reported sleep duration mitigates the association between inflammation and cognitive functioning in hospitalized older men Frontiers in psychology, 2015; 6(1): 1004.
Moieni Mona, Irwin Michael R, Jevtic Ivana, Olmstead Richard, Breen Elizabeth C, Eisenberger Naomi I   Sex differences in depressive and socioemotional responses to an inflammatory challenge: implications for sex differences in depression Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015; 40(7): 1709-16.
Irwin Michael R, Olmstead Richard, Carroll Judith E   Sleep Disturbance, Sleep Duration, and Inflammation: A Systematic Review and Meta-Analysis of Cohort Studies and Experimental Sleep Deprivation Biological psychiatry, 2015; 107(8): .
Carroll Judith E, Irwin Michael R, Stein Merkin Sharon, Seeman Teresa E   Sleep and multisystem biological risk: a population-based study PloS one, 2015; 10(2): e0118467.
Carroll Judith E, Carrillo Carmen, Olmstead Richard, Witarama Tuff, Breen Elizabeth C, Yokomizo Megumi, Seeman Teresa, Irwin Michael R   Sleep deprivation and divergent toll-like receptor-4 activation of cellular inflammation in aging Sleep, 2015; 38(2): 205-11.
Cho Hyong Jin, Seeman Teresa E, Kiefe Catarina I, Lauderdale Diane S, Irwin Michael R   Sleep disturbance and longitudinal risk of inflammation: Moderating influences of social integration and social isolation in the Coronary Artery Risk Development in Young Adults (CARDIA) study Brain, behavior, and immunity, 2015; 46(7): 319-26.
Irwin Michael R, Witarama Tuff, Caudill Marissa, Olmstead Richard, Breen Elizabeth Crabb   Sleep loss activates cellular inflammation and signal transducer and activator of transcription (STAT) family proteins in humans Brain, behavior, and immunity, 2015; 47: 86-92.
Chiang Jessica J, Bower Julienne E, Almeida David M, Irwin Michael R, Seeman Teresa E, Fuligni Andrew J   Socioeconomic status, daily affective and social experiences, and inflammation during adolescence Psychosomatic medicine, 2015; 77(3): 256-66.
Inagaki Tristen K, Muscatell Keely A, Irwin Michael R, Moieni Mona, Dutcher Janine M, Jevtic Ivana, Breen Elizabeth C, Eisenberger Naomi I   The role of the ventral striatum in inflammatory-induced approach toward support figures Brain, behavior, and immunity, 2015; 44(2): 247-52.
Moieni Mona, Irwin Michael R, Jevtic Ivana, Breen Elizabeth C, Cho Hyong Jin, Arevalo Jesusa M G, Ma Jeffrey, Cole Steven W, Eisenberger Naomi I   Trait sensitivity to social disconnection enhances pro-inflammatory responses to a randomized controlled trial of endotoxin Psychoneuroendocrinology, 2015; 62(12): 336-42.
Tabak Benjamin A, Meyer Meghan L, Castle Elizabeth, Dutcher Janine M, Irwin Michael R, Han Jung H, Lieberman Matthew D, Eisenberger Naomi I   Vasopressin, but not oxytocin, increases empathic concern among individuals who received higher levels of paternal warmth: A randomized controlled trial Psychoneuroendocrinology, 2015; 51(2): 253-61.
Irwin Michael R   Why sleep is important for health: a psychoneuroimmunology perspective Annual review of psychology, 2015; 66(2): 143-72.
Inagaki Tristen K, Muscatell Keely A, Moieni Mona, Dutcher Janine M, Jevtic Ivana, Irwin Michael R, Eisenberger Naomi I   Yearning for connection? Loneliness is associated with increased ventral striatum activity to close others Social cognitive and affective neuroscience, 2015; 107(8): .
Hoyt Michael A, Marin-Chollom Amanda M, Bower Julienne E, Thomas KaMala S, Irwin Michael R, Stanton Annette L   Approach and avoidance coping: diurnal cortisol rhythm in prostate cancer survivors Psychoneuroendocrinology, 2014; 49(50): 182-6.
Irwin Michael R, Olmstead Richard, Carrillo Carmen, Sadeghi Nina, Breen Elizabeth C, Witarama Tuff, Yokomizo Megumi, Lavretsky Helen, Carroll Judith E, Motivala Sarosh J, Bootzin Richard, Nicassio Perry   Cognitive behavioral therapy vs. Tai Chi for late life insomnia and inflammatory risk: a randomized controlled comparative efficacy trial Sleep, 2014; 37(9): 1543-52.
Ganz Patricia A, Petersen Laura, Castellon Steven A, Bower Julienne E, Silverman Daniel H S, Cole Steven W, Irwin Michael R, Belin Thomas R   Cognitive function after the initiation of adjuvant endocrine therapy in early-stage breast cancer: an observational cohort study Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014; 32(31): 3559-67.
Dzierzewski Joseph M, Fung Constance H, Jouldjian Stella, Alessi Cathy A, Irwin Michael R, Martin Jennifer L   Decrease in daytime sleeping is associated with improvement in cognition after hospital discharge in older adults Journal of the American Geriatrics Society, 2014; 62(1): 47-53.
Prasad Sandip M, Eggener Scott E, Lipsitz Stuart R, Irwin Michael R, Ganz Patricia A, Hu Jim C   Effect of depression on diagnosis, treatment, and mortality of men with clinically localized prostate cancer Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014; 32(23): 2471-8.
Black David S, O'Reilly Gillian A, Olmstead Richard, Breen Elizabeth C, Irwin Michael R   Mindfulness-based intervention for prodromal sleep disturbances in older adults: design and methodology of a randomized controlled trial Contemporary clinical trials, 2014; 39(1): 22-7.
Doering Lynn V, Chen Belinda, McGuire Anthony, Bodán Rebecca Cross, Irwin Michael R   Persistent depressive symptoms and pain after cardiac surgery Psychosomatic medicine, 2014; 76(6): 437-44.
Irwin Michael R   Sleep and inflammation in resilient aging Interface focus, 2014; 4(5): 20140009.
Black David S, Irwin Michael R, Olmstead Richard, Ji Ellen, Crabb Breen Elizabeth, Motivala Sarosh J   Tai chi meditation effects on nuclear factor-κB signaling in lonely older adults: a randomized controlled trial Psychotherapy and psychosomatics, 2014; 83(5): 315-7.
Irwin Michael R, Olmstead Richard, Breen Elizabeth C, Witarama Tuff, Carrillo Carmen, Sadeghi Nina, Arevalo Jesusa M G, Ma Jeffrey, Nicassio Perry, Ganz Patricia A, Bower Julienne E, Cole Steve   Tai chi, cellular inflammation, and transcriptome dynamics in breast cancer survivors with insomnia: a randomized controlled trial Journal of the National Cancer Institute. Monographs, 2014; 2014(50): 295-301.
Burklund Lisa J, Creswell J David, Irwin Michael R, Lieberman Matthew D   The common and distinct neural bases of affect labeling and reappraisal in healthy adults Frontiers in psychology, 2014; 5(6): 221.
Morgan Nani, Irwin Michael R, Chung Mei, Wang Chenchen   The effects of mind-body therapies on the immune system: meta-analysis PloS one, 2014; 9(7): e100903.
Bower Julienne E, Greendale Gail, Crosswell Alexandra D, Garet Deborah, Sternlieb Beth, Ganz Patricia A, Irwin Michael R, Olmstead Richard, Arevalo Jesusa, Cole Steve W   Yoga reduces inflammatory signaling in fatigued breast cancer survivors: a randomized controlled trial Psychoneuroendocrinology, 2014; 43(6): 20-9.
Griffis Charles A, Crabb Breen Elizabeth, Compton Peggy, Goldberg Alyssa, Witarama Tuff, Kotlerman Jenny, Irwin Michael R   Acute Painful Stress and Inflammatory Mediator Production Neuroimmunomodulation, 2013; 20(3): 127-133.
Hoyt Michael A, Stanton Annette L, Irwin Michael R, Thomas KaMala S   Cancer-related masculine threat, emotional approach coping, and physical functioning following treatment for prostate cancer Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2013; 32(1): 66-74.
Youngstedt Shawn D, Jean-Louis Girardin, Bootzin Richard R, Kripke Daniel F, Cooper Jonnifer, Dean Lauren R, Catao Fabio, James Shelli, Vining Caitlin, Williams Natasha J, Irwin Michael R   Chronic moderate sleep restriction in older long sleepers and older average duration sleepers: a randomized controlled trial Contemporary clinical trials, 2013; 36(1): 175-86.
Ganz Patricia A, Kwan Lorna, Castellon Steven A, Oppenheim Amy, Bower Julienne E, Silverman Daniel H S, Cole Steve W, Irwin Michael R, Ancoli-Israel Sonia, Belin Thomas R   Cognitive Complaints After Breast Cancer Treatments: Examining the Relationship With Neuropsychological Test Performance Journal of the National Cancer Institute, 2013; 31(13): .
Bower Julienne E, Ganz Patricia A, Irwin Michael R, Castellon Steven, Arevalo Jesusa, Cole Steven W   Cytokine genetic variations and fatigue among patients with breast cancer Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013; 31(13): 1656-61.
Irwin Michael R   Depression and insomnia in cancer: prevalence, risk factors, and effects on cancer outcomes Current psychiatry reports, 2013; 15(11): 404.
O'Connor Mary-Frances, Schultze-Florey Christian R, Irwin Michael R, Arevalo Jesusa M G, Cole Steven W   Divergent gene expression responses to Complicated Grief and Non-complicated Grief Brain, behavior, and immunity, 2013; .
Campo Rebecca A, O'Connor Kathleen, Light Kathleen C, Nakamura Yoshio, Lipschitz David L, Lastayo Paul C, Pappas Lisa, Boucher Kenneth, Irwin Michael R, Agarwal Neeraj, Kinney Anita Y   Feasibility and Acceptability of a Tai Chi Chih Randomized Controlled Trial in Senior Female Cancer Survivors Integrative cancer therapies, 2013; 31(13): .
Hoyt Michael A, Stanton Annette L, Bower Julienne E, Thomas Kamala S, Litwin Mark S, Breen Elizabeth C, Irwin Michael R   Inflammatory Biomarkers and Emotional Approach Coping in Men with Prostate Cancer Brain, behavior, and immunity, 2013; 31(13): .
Lee Eun, Cho Hyong Jin, Olmstead Richard, Levin Myron J, Oxman Michael N, Irwin Michael R   Persistent sleep disturbance: a risk factor for recurrent depression in community-dwelling older adults Sleep, 2013; 36(11): 1685-91.
Barsevick Andrea M, Irwin Michael R, Hinds Pamela, Miller Andrew, Berger Ann, Jacobsen Paul, Ancoli-Israel Sonia, Reeve Bryce B, Mustian Karen, O'Mara Ann, Lai Jin-Shei, Fisch Michael, Cella David, Cella David   Recommendations for high-priority research on cancer-related fatigue in children and adults Journal of the National Cancer Institute, 2013; 105(19): 1432-40.
Dimsdale Joel E, Creed Francis, Escobar Javier, Sharpe Michael, Wulsin Lawson, Barsky Arthur, Lee Sing, Irwin Michael R, Levenson James   Somatic symptom disorder: an important change in DSM Journal of psychosomatic research, 2013; 75(3): 223-8.
Pomykala K L, Ganz P A, Bower J E, Kwan L, Castellon S A, Mallam S, Cheng I, Ahn R, Breen E C, Irwin M R, Silverman D H S   The association between pro-inflammatory cytokines, regional cerebral metabolism, and cognitive complaints following adjuvant chemotherapy for breast cancer Brain imaging and behavior, 2013; 7(4): 511-23.
Irwin Michael R, Levin Myron J, Laudenslager Mark L, Olmstead Richard, Lucko Anne, Lang Nancy, Carrillo Carmen, Stanley Harold A, Caulfield Michael J, Weinberg Adriana, Chan Ivan S F, Clair Jim, Smith Jeff G, Marchese R D, Williams Heather M, Beck Danielle J, McCook Patricia T, Zhang Jane H, Johnson Gary, Oxman Michael N   Varicella zoster virus-specific immune responses to a herpes zoster vaccine in elderly recipients with major depression and the impact of antidepressant medications Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013; 56(8): 1085-93.
Nicassio Perry M, Ormseth Sarah R, Custodio Mara K, Irwin Michael R, Olmstead Richard, Weisman Michael H   A Multidimensional Model of Fatigue in Patients with Rheumatoid Arthritis The Journal of rheumatology, 2012; .
Lavretsky H, Epel E S, Siddarth P, Nazarian N, Cyr N St, Khalsa D S, Lin J, Blackburn E, Irwin M R   A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: effects on mental health, cognition, and telomerase activity International journal of geriatric psychiatry, 2012; .
Cho H J, Kivimäki M, Bower J E, Irwin M R   Association of C-reactive protein and interleukin-6 with new-onset fatigue in the Whitehall II prospective cohort study Psychological medicine, 2012; 32(1): 1-11.
Irwin Michael R, Rothermundt Matthias   Clinical psychoneuroimmunology Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn, 2012; 106(4): 211-25.
Nicassio Perry M, Ormseth Sarah R, Custodio Mara K, Olmstead Richard, Weisman Michael H, Irwin Michael R   Confirmatory Factor Analysis of the Pittsburgh Sleep Quality Index in Rheumatoid Arthritis Patients Behavioral sleep medicine, 2012; 32(1): .
Kierlin Lara, Olmstead Richard, Yokomizo Megumi, Nicassio Perry, Irwin Michael R   Diagnostic and Statistical Manual criteria for insomnia related impairment in daytime functioning: polysomnographic correlates in older adults Sleep medicine, 2012; 13(7): 958-60.
O'Connor Mary-Frances, Wellisch David K, Stanton Annette L, Olmstead Richard, Irwin Michael R   Diurnal cortisol in Complicated and Non-Complicated Grief: slope differences across the day Psychoneuroendocrinology, 2012; 37(5): 725-8.
Ganz Patricia A, Bower J E, Kwan L, Castellon S A, Silverman D H S, Geist C, Breen E C, Irwin M R, Cole S W   Does tumor necrosis factor-alpha (TNF-α) play a role in post-chemotherapy cerebral dysfunction? Brain, behavior, and immunity, 2012; .
Doering Lynn V, Chen Belinda, Cross Bodán Rebecca, Magsarili Marise C, Nyamathi Adey, Irwin Michael R   Early Cognitive Behavioral Therapy for Depression After Cardiac Surgery The Journal of cardiovascular nursing, 2012; .
Cho Hyong Jin, Bower Julienne E, Kiefe Catarina I, Seeman Teresa E, Irwin Michael R   Early life stress and inflammatory mechanisms of fatigue in the Coronary Artery Risk Development in Young Adults (CARDIA) study Brain, behavior, and immunity, 2012; 37(5): .
Ishii Shinya, Karlamangla Arun S, Bote Marcos, Irwin Michael R, Jacobs David R, Cho Hyong Jin, Seeman Teresa E   Gender, Obesity and Repeated Elevation of C-Reactive Protein: Data from the CARDIA Cohort PloS one, 2012; 7(4): e36062.
Inagaki Tristen K, Muscatell Keely A, Irwin Michael R, Cole Steve W, Eisenberger Naomi I   Inflammation selectively enhances amygdala activity to socially threatening images NeuroImage, 2012; 59(4): 3222-6.
Elderkin-Thompson Virginia, Irwin Michael R, Hellemann Gerhard, Kumar Anand   Interleukin-6 and memory functions of encoding and recall in healthy and depressed elderly adults The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012; 20(9): 753-63.
Creswell J David, Irwin Michael R, Burklund Lisa J, Lieberman Matthew D, Arevalo Jesusa M G, Ma Jeffrey, Breen Elizabeth Crabb, Cole Steven W   Mindfulness-Based Stress Reduction training reduces loneliness and pro-inflammatory gene expression in older adults: A small randomized controlled trial Brain, behavior, and immunity, 2012; 26(7): 1095-101.
Irwin Michael R   Sleep and infectious disease risk Sleep, 2012; 35(8): 1025-6.
Irwin Michael R, Olmstead Richard E, Ganz Patricia A, Haque Reina   Sleep disturbance, inflammation and depression risk in cancer survivors Brain, behavior, and immunity, 2012; .
Irwin Michael R, Olmstead Richard, Carrillo Carmen, Sadeghi Nina, Fitzgerald John D, Ranganath Veena K, Nicassio Perry M   Sleep loss exacerbates fatigue, depression, and pain in rheumatoid arthritis Sleep, 2012; 35(4): 537-43.
Nicassio Perry M, Ormseth Sarah R, Kay Morgan, Custodio Mara, Irwin Michael R, Olmstead Richard, Weisman Michael H   The contribution of pain and depression to self-reported sleep disturbance in patients with rheumatoid arthritis Pain, 2012; 153(1): 107-12.
Schultze-Florey Christian R, Martínez-Maza Otoniel, Magpantay Larry, Breen Elizabeth Crabb, Irwin Michael R, Gündel Harald, O'Connor Mary-Frances   When grief makes you sick: Bereavement induced systemic inflammation is a question of genotype Brain, behavior, and immunity, 2012; 26(7): 1066-71.
Black David S, Cole Steve W, Irwin Michael R, Breen Elizabeth, St Cyr Natalie M, Nazarian Nora, Khalsa Dharma S, Lavretsky Helen   Yogic meditation reverses NF-κB and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial Psychoneuroendocrinology, 2012; 13(7): .
Nicassio Perry M, Kay Morgan A, Custodio Mara K, Irwin Michael R, Olmstead Richard, Weisman Michael H   An evaluation of a biopsychosocial framework for health-related quality of life and disability in rheumatoid arthritis Journal of psychosomatic research, 2011; 71(2): 79-85.
Cole Steven W, Arevalo Jesusa M G, Manu Kavya, Telzer Eva H, Kiang Lisa, Bower Julienne E, Irwin Michael R, Fuligni Andrew J   Antagonistic pleiotropy at the human IL6 promoter confers genetic resilience to the pro-inflammatory effects of adverse social conditions in adolescence Developmental psychology, 2011; 47(4): 1173-80.
Lavretsky Helen, Alstein Lily L, Olmstead Richard E, Ercoli Linda M, Riparetti-Brown Marquertie, Cyr Natalie St, Irwin Michael R   Complementary use of tai chi chih augments escitalopram treatment of geriatric depression: a randomized controlled trial The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011; 19(10): 839-50.
Bower Julienne E, Ganz Patricia A, Irwin Michael R, Arevalo Jesusa M G, Cole Steve W   Fatigue and gene expression in human leukocytes: increased NF-κB and decreased glucocorticoid signaling in breast cancer survivors with persistent fatigue Brain, behavior, and immunity, 2011; 25(1): 147-50.
Bower Julienne E, Ganz Patricia A, Irwin Michael R, Kwan Lorna, Breen Elizabeth C, Cole Steve W   Inflammation and behavioral symptoms after breast cancer treatment: do fatigue, depression, and sleep disturbance share a common underlying mechanism? Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011; 29(26): 3517-22.
Irwin Michael R   Inflammation at the intersection of behavior and somatic symptoms The Psychiatric clinics of North America, 2011; 34(3): 605-20.
Irwin Michael R, Levin Myron J, Carrillo Carmen, Olmstead Richard, Lucko Anne, Lang Nancy, Caulfield Michael J, Weinberg Adriana, Chan Ivan S F, Clair Jim, Smith Jeff G, Marchese R D, Williams Heather M, Beck Danielle J, McCook Patricia T, Johnson Gary, Oxman Michael N   Major depressive disorder and immunity to varicella-zoster virus in the elderly Brain, behavior, and immunity, 2011; 25(4): 759-66.
Irwin Michael R, Olmstead Richard   Mitigating Cellular Inflammation in Older Adults: A Randomized Controlled Trial of Tai Chi Chih The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2011; 19(10): .
Irwin Michael R, Cole Steven W   Reciprocal regulation of the neural and innate immune systems Nature reviews. Immunology, 2011; 11(9): 625-32.
Thomas KaMala S, Motivala S, Olmstead R, Irwin M R   Sleep depth and fatigue: role of cellular inflammatory activation Brain, behavior, and immunity, 2011; 25(1): 53-8.
Bower Julienne E, Garet Deborah, Sternlieb Beth, Ganz Patricia A, Irwin Michael R, Olmstead Richard, Greendale Gail   Yoga for persistent fatigue in breast cancer survivors: A randomized controlled trial Cancer, 2011; 7(4): .
Lavretsky Helen, Siddarth Prabha, Irwin Michael R   Improving depression and enhancing resilience in family dementia caregivers: a pilot randomized placebo-controlled trial of escitalopram The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010; 18(2): 154-62.
Irwin Michael R, Olmstead Richard, Valladares Edwin M, Breen Elizabeth Crabb, Ehlers Cindy L   In response to: Etanercept for sleep in patients with Alcohol use disorder - mechanisms need to be elucidated Biological psychiatry, 2010; 67(1): e3.
Eisenberger Naomi I, Inagaki Tristen K, Mashal Nehjla M, Irwin Michael R   Inflammation and social experience: an inflammatory challenge induces feelings of social disconnection in addition to depressed mood Brain, behavior, and immunity, 2010; 24(4): 558-63.
Eisenberger Naomi I, Berkman Elliot T, Inagaki Tristen K, Rameson Lian T, Mashal Nehjla M, Irwin Michael R   Inflammation-induced anhedonia: endotoxin reduces ventral striatum responses to reward Biological psychiatry, 2010; 68(8): 748-54.
O'Connor M-F, Irwin M R   Links between behavioral factors and inflammation Clinical pharmacology and therapeutics, 2010; 87(4): 479-82.
Cho Hyong Jin, Lavretsky Helen, Olmstead Richard, Levin Myron, Oxman Michael N, Irwin Michael R   Prior depression history and deterioration of physical health in community-dwelling older adults--a prospective cohort study The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010; 18(5): 442-51.
Fuligni Andrew J, Telzer Eva H, Bower Julienne, Cole Steve W, Kiang Lisa, Irwin Michael R   A preliminary study of daily interpersonal stress and C-reactive protein levels among adolescents from Latin American and European backgrounds Psychosomatic medicine, 2009; 71(3): 329-33.
Eisenberger Naomi I, Inagaki Tristen K, Rameson Lian T, Mashal Nehjla M, Irwin Michael R   An fMRI study of cytokine-induced depressed mood and social pain: the role of sex differences NeuroImage, 2009; 47(3): 881-90.
Fuligni Andrew J, Telzer Eva H, Bower Julienne, Irwin Michael R, Kiang Lisa, Cole Steve W   Daily family assistance and inflammation among adolescents from Latin American and European backgrounds Brain, behavior, and immunity, 2009; 23(6): 803-9.
Gold Stefan M, Irwin Michael R   Depression and immunity: inflammation and depressive symptoms in multiple sclerosis Immunology and allergy clinics of North America, 2009; 29(2): 309-20.
Creswell J David, Myers Hector F, Cole Steven W, Irwin Michael R   Mindfulness meditation training effects on CD4+ T lymphocytes in HIV-1 infected adults: a small randomized controlled trial Brain, behavior, and immunity, 2009; 23(2): 184-8.
Motivala Sarosh J, Tomiyama A Janet, Ziegler Michael, Khandrika Srikrishna, Irwin Michael R   Nocturnal levels of ghrelin and leptin and sleep in chronic insomnia Psychoneuroendocrinology, 2009; 34(4): 540-5.
Cho HJ, Seeman TE, Bower JE, Kiefe CI, Irwin MR.   Prospective Association Between C-Reactive Protein and Fatigue in the Coronary Artery Risk Development in Young Adults Study Biological psychiatry, 2009; 23(6): .
Irwin MR, Carrillo C, Olmstead R.   Sleep loss activates cellular markers of inflammation: Sex differences Brain, behavior, and immunity, 2009; 122(12): .
Dickerson SS, Gable SL, Irwin MR, Aziz N, Kemeny ME.   Social-Evaluative Threat and Proinflammatory Cytokine Regulation: An Experimental Laboratory Investigation Psychological science : a journal of the American Psychological Society / APS, 2009; 200(7): .
Frasure-Smith Nancy, Lespérance François, Irwin Michael R, Talajic Mario, Pollock Bruce G   The relationships among heart rate variability, inflammatory markers and depression in coronary heart disease patients Brain, behavior, and immunity, 2009; 23(8): 1140-7.
O'Connor Mary-Frances, Bower Julie E, Cho Hyong Jin, Creswell J David, Dimitrov Stoyan, Hamby Mary E, Hoyt Michael A, Martin Jennifer L, Robles Theodore F, Sloan Erica K, Thomas Kamala S, Irwin Michael R   To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers Brain, behavior, and immunity, 2009; 23(7): 887-97.
Irwin Michael R, Olmstead Richard, Valladares Edwin M, Breen Elizabeth Crabb, Ehlers Cindy L   Tumor necrosis factor antagonism normalizes rapid eye movement sleep in alcohol dependence Biological psychiatry, 2009; 66(2): 191-5.
Weinberg Adriana, Zhang Jane H, Oxman Michael N, Johnson Gary R, Hayward Anthony R, Caulfield Michael J, Irwin Michael R, Clair James, Smith Jeffrey G, Stanley Harold, Marchese Rocio D, Harbecke Ruth, Williams Heather M, Chan Ivan S F, Arbeit Robert D, Gershon Anne A, Schödel Florian, Morrison Vicki A, Kauffman Carol A, Straus Steve E, Schmader Kenneth E, Davis Larry E, Levin Myron J, Levin Myron J   Varicella-zoster virus-specific immune responses to herpes zoster in elderly participants in a trial of a clinically effective zoster vaccine The Journal of infectious diseases, 2009; 200(7): 1068-77.
O'Connor Mary-Frances, Irwin Michael R, Wellisch David K   When grief heats up: pro-inflammatory cytokines predict regional brain activation NeuroImage, 2009; 47(3): 891-6.
Klumpp Klaus, Kalayanov Genadiy, Ma Han, Le Pogam Sophie, Leveque Vincent, Jiang Wen-Rong, Inocencio Nicole, De Witte Anniek, Rajyaguru Sonal, Tai Ezra, Chanda Sushmita, Irwin Michael R, Sund Christian, Winqist Anna, Maltseva Tatiana, Eriksson Staffan, Usova Elena, Smith Mark, Alker Andre, Najera Isabel, Cammack Nick, Martin Joseph A, Johansson Nils Gunnar, Smith David B   2'-deoxy-4'-azido nucleoside analogs are highly potent inhibitors of hepatitis C virus replication despite the lack of 2'-alpha-hydroxyl groups The Journal of biological chemistry, 2008; 283(4): 2167-75.
Irwin Michael R, Davis Mary, Zautra Alex   Behavioral Comorbidities in Rheumatoid Arthritis: A Psychoneuroimmunological Perspective The Psychiatric times, 2008; 25(9): 1.
Davis Mary C, Zautra Alex J, Younger Jarred, Motivala Sarosh J, Attrep Jeanne, Irwin Michael R   Chronic stress and regulation of cellular markers of inflammation in rheumatoid arthritis: implications for fatigue Brain, behavior, and immunity, 2008; 22(1): 24-32.
Zautra Alex J, Davis Mary C, Reich John W, Nicassario Perry, Tennen Howard, Finan Patrick, Kratz Anna, Parrish Brendt, Irwin Michael R   Comparison of cognitive behavioral and mindfulness meditation interventions on adaptation to rheumatoid arthritis for patients with and without history of recurrent depression Journal of consulting and clinical psychology, 2008; 76(3): 408-21.
O'Connor Mary-Frances, Wellisch David K, Stanton Annette L, Eisenberger Naomi I, Irwin Michael R, Lieberman Matthew D   Craving love? Enduring grief activates brain's reward center NeuroImage, 2008; 42(2): 969-72.
Collado-Hidalgo Alicia, Bower Julienne E, Ganz Patricia A, Irwin Michael R, Cole Steve W   Cytokine gene polymorphisms and fatigue in breast cancer survivors: early findings Brain, behavior, and immunity, 2008; 22(8): 1197-200.
Irwin Michael R   Human psychoneuroimmunology: 20 years of discovery Brain, behavior, and immunity, 2008; 22(2): 129-39.
Dantzer Robert, Capuron Lucile, Irwin Michael R, Miller Andrew H, Ollat Helene, Perry Victor Hugh, Rousey Sarah, Yirmiya Raz   Identification and treatment of symptoms associated with inflammation in medically ill patients Psychoneuroendocrinology, 2008; 33(1): 18-29.
Irwin Michael R, Olmstead Richard, Motivala Sarosh J   Improving sleep quality in older adults with moderate sleep complaints: A randomized controlled trial of Tai Chi Chih Sleep, 2008; 31(7): 1001-8.
Miller Andrew H, Ancoli-Israel Sonia, Bower Julienne E, Capuron Lucile, Irwin Michael R   Neuroendocrine-immune mechanisms of behavioral comorbidities in patients with cancer Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008; 26(6): 971-82.
Irwin Matthew R, Downey Donald B, Gardi Lori, Fenster Aaron   Registered 3-D ultrasound and digital stereotactic mammography for breast biopsy guidance IEEE transactions on medical imaging, 2008; 27(3): 391-401.
Valladares Edwin M, Eljammal Sam M, Motivala Sarosh, Ehlers Cindy L, Irwin Michael R   Sex differences in cardiac sympathovagal balance and vagal tone during nocturnal sleep Sleep medicine, 2008; 9(3): 310-6.
Cho Hyong Jin, Lavretsky Helen, Olmstead Richard, Levin Myron J, Oxman Michael N, Irwin Michael R   Sleep disturbance and depression recurrence in community-dwelling older adults: a prospective study The American journal of psychiatry, 2008; 165(12): 1543-50.
Irwin Michael R, Wang Minge, Ribeiro Denise, Cho Hyong Jin, Olmstead Richard, Breen Elizabeth Crabb, Martinez-Maza Otoniel, Cole Steve   Sleep loss activates cellular inflammatory signaling Biological psychiatry, 2008; 64(6): 538-40.
Motivala Sarosh J, Khanna Dinesh, FitzGerald John, Irwin Michael R   Stress activation of cellular markers of inflammation in rheumatoid arthritis: protective effects of tumor necrosis factor alpha antagonists Arthritis and rheumatism, 2008; 58(2): 376-83.
Levin M J, Oxman M N, Zhang J H, Johnson G R, Stanley H, Hayward A R, Caulfield M J, Irwin M R, Smith J G, Clair J, Chan I S F, Williams H, Harbecke R, Marchese R, Straus S E, Gershon A, Weinberg A, Weinberg A   Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccine The Journal of infectious diseases, 2008; 197(6): 825-35.
Irwin Michael R, Olmstead Richard, Oxman Michael N   Augmenting immune responses to varicella zoster virus in older adults: a randomized, controlled trial of Tai Chi Journal of the American Geriatrics Society, 2007; 55(4): 511-7.
Redwine Laura S, Mills Paul J, Hong Suzi, Rutledge Thomas, Reis Veronica, Maisel Alan, Irwin Michael R   Cardiac-related hospitalization and/or death associated with immune dysregulation and symptoms of depression in heart failure patients Psychosomatic medicine, 2007; 69(1): 23-9.
Irwin Michael R, Olmos Luis, Wang Minge, Valladares Edwin M, Motivala Sarosh J, Fong Tim, Newton Tom, Butch Anthony, Olmstead Richard, Cole Steve W   Cocaine dependence and acute cocaine induce decreases of monocyte proinflammatory cytokine expression across the diurnal period: autonomic mechanisms The Journal of pharmacology and experimental therapeutics, 2007; 320(2): 507-15.
Meeks Thomas W, Wetherell Julie L, Irwin Michael R, Redwine Laura S, Jeste Dilip V   Complementary and alternative treatments for late-life depression, anxiety, and sleep disturbance: a review of randomized controlled trials The Journal of clinical psychiatry, 2007; 68(10): 1461-71.
Irwin Michael R   Depression and risk of cancer progression: an elusive link Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007; 25(17): 2343-4.
Frasure-Smith Nancy, Lespérance François, Irwin Michael R, Sauvé Claude, Lespérance Jacques, Théroux Pierre   Depression, C-reactive protein and two-year major adverse cardiac events in men after acute coronary syndromes Biological psychiatry, 2007; 62(4): 302-8.
Irwin Michael R, Miller Andrew H   Depressive disorders and immunity: 20 years of progress and discovery Brain, behavior, and immunity, 2007; 21(4): 374-83.
Valladares Edwin M, Eljammal Sam M, Iyer Anand V, Irwin Michael R   EEG and vagal tone degradation during nocturnal sleep in abstinent alcohol dependence Sleep medicine, 2007; 8(3): 284-5.
Bower Julienne E, Ganz Patricia A, Aziz Najib, Olmstead Richard, Irwin Michael R, Cole Steve W   Inflammatory responses to psychological stress in fatigued breast cancer survivors: relationship to glucocorticoids Brain, behavior, and immunity, 2007; 21(3): 251-8.
Griffis Charles A, Irwin Michael R, Martinez-Maza Otoniel, Doering Lynn, Nyamathi Adeline, Kaufman Robert, Elashoff David, Aziz Najib, Compton Peggy   Pain-related activation of leukocyte cellular adhesion molecules: preliminary findings Neuroimmunomodulation, 2007; 14(5): 224-8.
Valladares Edwin M, Irwin Michael R   Polysomnographic sleep dysregulation in cocaine dependence TheScientificWorldJournal, 2007; 7(1): 213-6.
O'Connor Mary-Frances, Irwin Michael R, Seldon Joyce, Kwan Lorna, Ganz Patricia A   Pro-inflammatory cytokines and depression in a familial cancer registry Psycho-oncology, 2007; 16(5): 499-501.
O'Connor Mary-Frances, Motivala Sarosh J, Valladares Edwin M, Olmstead Richard, Irwin Michael R   Sex differences in monocyte expression of IL-6: role of autonomic mechanisms American journal of physiology. Regulatory, integrative and comparative physiology, 2007; 293(1): R145-51.
Irwin Michael R, Valladares Edwin M, Motivala Sarosh, Thayer Julian F, Ehlers Cindy L   Association between nocturnal vagal tone and sleep depth, sleep quality, and fatigue in alcohol dependence Psychosomatic medicine, 2006; 68(1): 159-66.
Irwin Michael R, Cole Jason C, Nicassio Perry M   Comparative meta-analysis of behavioral interventions for insomnia and their efficacy in middle-aged adults and in older adults 55+ years of age Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2006; 25(1): 3-14.
Gold Stefan M, Irwin Michael R   Depression and immunity: inflammation and depressive symptoms in multiple sclerosis Neurologic clinics, 2006; 24(3): 507-19.
Pike Jennifer L, Irwin Michael R   Dissociation of inflammatory markers and natural killer cell activity in major depressive disorder Brain, behavior, and immunity, 2006; 20(2): 169-74.
Motivala Sarosh J, Levin Myron J, Oxman Michael N, Irwin Michael R   Impairments in health functioning and sleep quality in older adults with a history of depression Journal of the American Geriatrics Society, 2006; 54(8): 1184-91.
Collado-Hidalgo Alicia, Bower Julienne E, Ganz Patricia A, Cole Steve W, Irwin Michael R   Inflammatory biomarkers for persistent fatigue in breast cancer survivors Clinical cancer research : an official journal of the American Association for Cancer Research, 2006; 12(9): 2759-66.
Eljammal Sam M, Valladares Edwin M, Irwin Michael R   Loss of slow-wave sleep Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2006; 2(2): 213-4.
Cole Jason C, Khanna Dinesh, Clements Philip J, Seibold James R, Tashkin Donald P, Paulus Harold E, Irwin Michael R, Motivala Sarosh J, Furst Daniel E   Single-factor scoring validation for the Health Assessment Questionnaire-Disability Index (HAQ-DI) in patients with systemic sclerosis and comparison with early rheumatoid arthritis patients Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2006; 15(8): 1383-94.
Irwin Michael R, Wang Minge, Campomayor Capella O, Collado-Hidalgo Alicia, Cole Steve   Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation Archives of internal medicine, 2006; 166(16): 1756-62.
Motivala Sarosh J, Sollers John, Thayer Julian, Irwin Michael R   Tai Chi Chih acutely decreases sympathetic nervous system activity in older adults The journals of gerontology. Series A, Biological sciences and medical sciences, 2006; 61(11): 1177-80.
Cole Jason C, Motivala Sarosh J, Buysse Daniel J, Oxman Michael N, Levin Myron J, Irwin Michael R   Validation of a 3-factor scoring model for the Pittsburgh sleep quality index in older adults Sleep, 2006; 29(1): 112-6.
Oxman M N, Levin M J, Johnson G R, Schmader K E, Straus S E, Gelb L D, Arbeit R D, Simberkoff M S, Gershon A A, Davis L E, Weinberg A, Boardman K D, Williams H M, Zhang J Hongyuan, Peduzzi P N, Beisel C E, Morrison V A, Guatelli J C, Brooks P A, Kauffman C A, Pachucki C T, Neuzil K M, Betts R F, Wright P F, Griffin M R, Brunell P, Soto N E, Marques A R, Keay S K, Goodman R P, Cotton D J, Gnann J W, Loutit J, Holodniy M, Keitel W A, Crawford G E, Yeh S-S, Lobo Z, Toney J F, Greenberg R N, Keller P M, Harbecke R, Hayward A R, Irwin M R, Kyriakides T C, Chan C Y, Chan I S F, Wang W W B, Annunziato P W, Silber J L, Silber J L   A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults The New England journal of medicine, 2005; 352(22): 2271-84.
Motivala SJ, Sarfatti A, Olmos L, Irwin MR   Inflammatory markers and sleep disturbance in major depression Psychosomatic medicine. , 2005; 67(2): 187-94.
Motivala Sarosh J, Sarfatti Avishay, Olmos Luis, Irwin Michael R   Inflammatory markers and sleep disturbance in major depression Psychosomatic medicine, 2005; 67(2): 187-94.
Cole Jason C, Motivala Sarosh J, Khanna Dinesh, Lee Jessica Y, Paulus Harold E, Irwin Michael R   Validation of single-factor structure and scoring protocol for the Health Assessment Questionnaire-Disability Index Arthritis and rheumatism, 2005; 53(4): 536-42.
Redwine L, Dang J, Irwin M   Cellular adhesion molecule expression, nocturnal sleep, and partial night sleep deprivation Brain, behavior, and immunity. , 2004; 18(4): 333-40.
Irwin Michael R, Rinetti Gina   Disordered sleep, nocturnal cytokines, and immunity: interactions between alcohol dependence and African-American ethnicity Alcohol (Fayetteville, N.Y.), 2004; 32(1): 53-61.
Zautra AJ, Yocum DC, Villanueva I, Smith B, Davis MC, Attrep J, Irwin M   Immune activation and depression in women with rheumatoid arthritis The Journal of rheumatology. , 2004; 31(3): 457-63.
Irwin M, Rinetti G, Redwine L, Motivala S, Dang J, Ehlers C   Nocturnal proinflammatory cytokine-associated sleep disturbances in abstinent African American alcoholics Brain, behavior, and immunity. , 2004; 18(4): 349-60.
Aziz Najib, Irwin Michael R, Dickerson Sally S, Butch Anthony W   Spurious tumor necrosis factor-alpha and interleukin-6 production by human monocytes from blood collected in endotoxin-contaminated vacutainer blood collection tubes Clinical chemistry, 2004; 50(11): 2215-6.
Kuhlwein E, Hauger RL, Irwin MR   Abnormal nocturnal melatonin secretion and disordered sleep in abstinent alcoholics Biol Psychiatry, 2003; 54(12): 1437-43.
Kühlwein Eva, Hauger Richard L, Irwin Michael R   Abnormal nocturnal melatonin secretion and disordered sleep in abstinent alcoholics Biological psychiatry, 2003; 54(12): 1437-43.
Redwine L, Snow S, Mills P, Irwin M   Acute psychological stress: effects on chemotaxis and cellular adhesion molecule expression Psychosomatic medicine. , 2003; 65(4): 598-603.
Redwine L, Dang J, Hall M, Irwin M   Disordered sleep, nocturnal cytokines, and immunity in alcoholics Psychosomatic medicine. , 2003; 65(1): 75-85.
Irwin Michael R, Pike Jennifer L, Cole Jason C, Oxman Michael N   Effects of a behavioral intervention, Tai Chi Chih, on varicella-zoster virus specific immunity and health functioning in older adults Psychosomatic medicine, 2003; 65(5): 824-30.
Grant Igor, Adler Karen A, Patterson Thomas L, Dimsdale Joel E, Ziegler Michael G, Irwin Michael R   Health consequences of Alzheimer's caregiving transitions: effects of placement and bereavement Psychosomatic medicine, 2003; 64(3): 477-86.
Motivala SJ, Dang J, Obradovic T, Meadows GG, Butch AW, Irwin MR   Leptin and cellular and innate immunity in abstinent alcoholics and controls Alcoholism, clinical and experimental research. , 2003; 27(11): 1819-24.
Motivala Sarosh J, Dang Jeff, Obradovic Tanja, Meadows Gary G, Butch Anthony W, Irwin Michael R   Leptin and cellular and innate immunity in abstinent alcoholics and controls Alcoholism, clinical and experimental research, 2003; 27(11): 1819-24.
Irwin M, Clark C, Kennedy B, Christian Gillin J, Ziegler M   Nocturnal catecholamines and immune function in insomniacs, depressed patients, and control subjects Brain, behavior, and immunity. , 2003; 17(5): 365-72.

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