Lori Altshuler, M.D.

A Short Biography:

Dr. Altshuler is a Professor-in-Residence in the UCLA Department of Psychiatry and Biobehavioral Sciences and holds the Julia S. Gouw Endowed Chair for Mood Disorders. She received her bachelor and M.D. degrees from Cornell and completed a two-year fellowship at the Biological Psychiatry Branch of the NIMH. In 1989 she was appointed assistant clinical professor at the UCLA Neuropsychiatric Institute and in her first year on faculty received the UCLA Neuropsychiatric Hospital Junior Faculty Distinguished Teaching Award. She has been an active teacher and mentor, and has been the recipient of numerous awards including, in 1994 and again in 2004, the UCLA Department of Psychiatry Outstanding Research Mentor Award. In 2006 she received the Gerald L. Klerman Distinguished Investigator Award from the Depression and Bipolar Support Alliance, and the National Nola Maddox Falcone Prize from NARSAD for Outstanding Achievement in Affective Disorders Research.

Work Titles
CTSI Member, CTSI Member, Workforce Development
UCLA Research Director, Resnick Neuropsychiatric Hospital Professor, Psychiatry and Biobehavioral Sciences Member, Brain Research Institute Member, Jane and Terry Semel Institute for Neuroscience and Human Behavior Member, Neuroscience GPB Home Area
VA Greater Los Angeles Healthcare System Chief, Bipolar Disorder Clinic Chief, Mental Health Clinic
Education:
Degrees:
M.D., Cornell Medical College, New York, NY, 1978 - 1982
B.A., Cornell University, New York, NY, 1974 - 1978
Fellowship:
1986 - 1989 National Institute of Mental Health, Bethesda, MD
Internship:
1982 - 1983 UCLA Center for Health Sciences/Wadsworth VA Hospital
1982 - 1983 UCLA Neuropsychiatric Hospital
Residency:
1983 - 1986 UCLA Neuropsychiatric Institute and Hospital
Certifications:
Certifications:
1989 American Board of Psychiatry and Neurology

Contact Information:

Fax Number:

310-794-9915

Detailed Biography:

Dr. Altshuler is a Professor-in-Residence in the UCLA Department of Psychiatry and Biobehavioral Sciences and holds the Julia S. Gouw Endowed Chair for Mood Disorders. She received her bachelor and M.D. degrees from Cornell and completed a two-year fellowship at the Biological Psychiatry Branch of the NIMH. In 1989 she was appointed assistant clinical professor at the UCLA Neuropsychiatric Institute and in her first year on faculty received the UCLA Neuropsychiatric Hospital Junior Faculty Distinguished Teaching Award. She has been an active teacher and mentor, and has been the recipient of numerous awards including, in 1994 and again in 2004, the UCLA Department of Psychiatry Outstanding Research Mentor Award. In 2006 she received the Gerald L. Klerman Distinguished Investigator Award from the Depression and Bipolar Support Alliance, and the National Nola Maddox Falcone Prize from NARSAD for Outstanding Achievement in Affective Disorders Research.

Publications:

A selected list of publications:

Abulseoud Osama A, Gitlin Michael, Altshuler Lori, Frye Mark A   Baseline thyroid indices and the subsequent response to citalopram treatment, a pilot study Brain and behavior, 2013; 3(2): 89-94.
Torgerson Carinna M, Irimia Andrei, Leow Alex D, Bartzokis George, Moody Teena D, Jennings Robin G, Alger Jeffry R, Van Horn John Darrell, Altshuler Lori L   DTI tractography and white matter fiber tract characteristics in euthymic bipolar I patients and healthy control subjects Brain imaging and behavior, 2013; 7(2): 129-39.
Torrisi Salvatore, Moody Teena D, Vizueta Nathalie, Thomason Moriah E, Monti Martin M, Townsend Jennifer D, Bookheimer Susan Y, Altshuler Lori L   Differences in resting corticolimbic functional connectivity in bipolar I euthymia Bipolar disorders, 2013; 15(2): 156-66.
Townsend Jennifer D, Torrisi Salvatore J, Lieberman Matthew D, Sugar Catherine A, Bookheimer Susan Y, Altshuler Lori L   Frontal-amygdala connectivity alterations during emotion downregulation in bipolar I disorder Biological psychiatry, 2013; 73(2): 127-35.
Townsend Jennifer D, Sugar Catherine A, Walshaw Patricia D, Vasquez Roxanne E, Foland-Ross Lara C, Moody Teena D, Bookheimer Susan Y, McGough James J, Altshuler Lori L   Frontostriatal neuroimaging findings differ in patients with bipolar disorder who have or do not have ADHD comorbidity Journal of affective disorders, 2013; 147(1-3): 389-96.
Leow Alex, Ajilore Olusola, Zhan Liang, Arienzo Donatello, GadElkarim Johnson, Zhang Aifeng, Moody Teena, Van Horn John, Feusner Jamie, Kumar Anand, Thompson Paul, Altshuler Lori   Impaired inter-hemispheric integration in bipolar disorder revealed with brain network analyses Biological psychiatry, 2013; 73(2): 183-93.
Post Robert M, Altshuler Lori L, Leverich Gabriele S, Frye Mark A, Suppes Trisha, McElroy Susan L, Keck Paul E, Nolen Willem A, Kupka Ralph W, Grunze Heinz, Rowe Mike   Role of childhood adversity in the development of medical co-morbidities associated with bipolar disorder Journal of affective disorders, 2013; 147(1-3): 288-94.
Lee Junghee, Altshuler Lori, Glahn David C, Miklowitz David J, Ochsner Kevin, Green Michael F   Social and nonsocial cognition in bipolar disorder and schizophrenia: relative levels of impairment The American journal of psychiatry, 2013; 170(3): 334-41.
Foland-Ross Lara C, Thompson Paul M, Sugar Catherine A, Narr Katherine L, Penfold Conor, Vasquez Roxanne E, Townsend Jennifer, Fischer Jeffrey, Saharan Priya, Bearden Carrie E, Altshuler Lori L   Three-dimensional mapping of hippocampal and amygdalar structure in euthymic adults with bipolar disorder not treated with lithium Psychiatry research, 2013; 211(3): 195-201.
Hegarty Catherine E, Foland-Ross Lara C, Narr Katherine L, Sugar Catherine A, McGough James J, Thompson Paul M, Altshuler Lori L   ADHD comorbidity can matter when assessing cortical thickness abnormalities in patients with bipolar disorder Bipolar disorders, 2012; 14(8): 843-55.
Hegarty Catherine E, Foland-Ross Lara C, Narr Katherine L, Townsend Jennifer D, Bookheimer Susan Y, Thompson Paul M, Altshuler Lori L   Anterior cingulate activation relates to local cortical thickness Neuroreport, 2012; 23(7): 420-4.
Jahshan Carol, Wynn Jonathan K, Mathis Kristopher I, Altshuler Lori L, Glahn David C, Green Michael F   Cross-diagnostic comparison of duration mismatch negativity and P3a in bipolar disorder and schizophrenia Bipolar disorders, 2012; 14(3): 239-48.
Townsend Jennifer D, Bookheimer Susan Y, Foland-Ross Lara C, Moody Teena D, Eisenberger Naomi I, Fischer Jeffrey S, Cohen Mark S, Sugar Catherine A, Altshuler Lori L   Deficits in inferior frontal cortex activation in euthymic bipolar disorder patients during a response inhibition task Bipolar disorders, 2012; 14(4): 442-50.
Townsend Jennifer, Altshuler Lori L   Emotion processing and regulation in bipolar disorder: a review Bipolar disorders, 2012; 14(4): 326-39.
Foland-Ross Lara C, Brooks John O, Mintz Jim, Bartzokis George, Townsend Jennifer, Thompson Paul M, Altshuler Lori L   Mood-state effects on amygdala volume in bipolar disorder Journal of affective disorders, 2012; 14(3): .
Bartzokis George, Lu Po H, Heydari Panthea, Couvrette Alexander, Lee Grace J, Kalashyan Greta, Freeman Frank, Grinstead John W, Villablanca Pablo, Finn J Paul, Mintz Jim, Alger Jeffry R, Altshuler Lori L   Multimodal magnetic resonance imaging assessment of white matter aging trajectories over the lifespan of healthy individuals Biological psychiatry, 2012; 72(12): 1026-34.
Foland-Ross Lara C, Bookheimer Susan Y, Lieberman Matthew D, Sugar Catherine A, Townsend Jennifer D, Fischer Jeffrey, Torrisi Salvatore, Penfold Conor, Madsen Sarah K, Thompson Paul M, Altshuler Lori L   Normal amygdala activation but deficient ventrolateral prefrontal activation in adults with bipolar disorder during euthymia NeuroImage, 2012; 59(1): 738-44.
Vizueta Nathalie, Rudie Jeffrey D, Townsend Jennifer D, Torrisi Salvatore, Moody Teena D, Bookheimer Susan Y, Altshuler Lori L   Regional fMRI hypoactivation and altered functional connectivity during emotion processing in nonmedicated depressed patients with bipolar II disorder The American journal of psychiatry, 2012; 169(8): 831-40.
Post Robert M, Leverich Gabriele S, Altshuler Lori L, Frye Mark A, Suppes Trisha, McElroy Susan L, Keck Paul E, Nolen Willem A, Rowe Mike, Kupka Ralph W, Grunze Heinz, Goodwin Frederick K   Relationship of prior antidepressant exposure to long-term prospective outcome in bipolar I disorder outpatients The Journal of clinical psychiatry, 2012; 14(3): .
Strakowski Stephen M, Adler Caleb M, Almeida Jorge, Altshuler Lori L, Blumberg Hilary P, Chang Kiki D, DelBello Melissa P, Frangou Sophia, McIntosh Andrew, Phillips Mary L, Sussman Jessika E, Townsend Jennifer D   The functional neuroanatomy of bipolar disorder: a consensus model Bipolar disorders, 2012; 14(4): 313-25.
Suri Rita, Hellemann Gerhard, Stowe Zachary N, Cohen Lee S, Aquino Ana, Altshuler Lori L   A prospective, naturalistic, blinded study of early neurobehavioral outcomes for infants following prenatal antidepressant exposure The Journal of clinical psychiatry, 2011; 72(7): 1002-7.
Post Robert M, Leverich Gabriele S, Altshuler Lori L, Frye Mark A, Suppes Trisha, Keck Paul E, McElroy Susan L, Nolen Willem A, Kupka Ralph, Grunze Heinz, Walden Joerg, Rowe Mike   Differential clinical characteristics, medication usage, and treatment response of bipolar disorder in the US versus The Netherlands and Germany International clinical psychopharmacology, 2011; 26(2): 96-106.
Bartzokis George, Lu Po H, Tingus Kathleen, Peters Douglas G, Amar Chetan P, Tishler Todd A, Finn J Paul, Villablanca Pablo, Altshuler Lori L, Mintz Jim, Neely Elizabeth, Connor James R   Gender and iron genes may modify associations between brain iron and memory in healthy aging Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011; 36(7): 1375-84.
Foland-Ross Lara C, Thompson Paul M, Sugar Catherine A, Madsen Sarah K, Shen Jim K, Penfold Conor, Ahlf Kyle, Rasser Paul E, Fischer Jeffrey, Yang Yilan, Townsend Jennifer, Bookheimer Susan Y, Altshuler Lori L   Investigation of cortical thickness abnormalities in lithium-free adults with bipolar I disorder using cortical pattern matching The American journal of psychiatry, 2011; 168(5): 530-9.
Bartzokis George, Lu Po H, Amar Chetan P, Raven Erika P, Detore Nicole R, Altshuler Lori L, Mintz Jim, Ventura Joseph, Casaus Laurie R, Luo John S, Subotnik Kenneth L, Nuechterlein Keith H   Long acting injection versus oral risperidone in first-episode schizophrenia: differential impact on white matter myelination trajectory Schizophrenia research, 2011; 132(1): 35-41.
Brooks John O, Foland-Ross Lara C, Thompson Paul M, Altshuler Lori L   Preliminary evidence of within-subject changes in gray matter density associated with remission of bipolar depression Psychiatry research, 2011; 193(1): 53-5.
Tishler Todd A, Raven Erika P, Lu Po H, Altshuler Lori L, Bartzokis George   Premenopausal hysterectomy is associated with increased brain ferritin iron Neurobiology of aging, 2011; 132(1): .
McElroy Susan L, Frye Mark A, Hellemann Gerhard, Altshuler Lori, Leverich Gabriele S, Suppes Trisha, Keck Paul E, Nolen Willem A, Kupka Ralph, Post Robert M   Prevalence and correlates of eating disorders in 875 patients with bipolar disorder Journal of affective disorders, 2011; 128(3): 191-8.
Yan-Meier Leslie, Eberhart Nicole K, Hammen Constance L, Gitlin Michael, Sokolski Kenneth, Altshuler Lori   Stressful life events predict delayed functional recovery following treatment for mania in bipolar disorder Psychiatry research, 2011; 186(2-3): 267-71.
Hallahan Brian, Newell John, Soares Jair C, Brambilla Paolo, Strakowski Stephen M, Fleck David E, Kieseppä Tuula, Altshuler Lori L, Fornito Alex, Malhi Gin S, McIntosh Andrew M, Yurgelun-Todd Deborah A, Labar Kevin S, Sharma Verinder, MacQueen Glenda M, Murray Robin M, McDonald Colm   Structural magnetic resonance imaging in bipolar disorder: an international collaborative mega-analysis of individual adult patient data Biological psychiatry, 2011; 69(4): 326-35.
Gitlin Michael J, Mintz Jim, Sokolski Kenneth, Hammen Constance, Altshuler Lori L   Subsyndromal depressive symptoms after symptomatic recovery from mania are associated with delayed functional recovery The Journal of clinical psychiatry, 2011; 72(5): 692-7.
Bearden Carrie E, Shih Vivian H, Green Michael F, Gitlin Michael, Sokolski Kenneth N, Levander Eric, Marusak Susan, Hammen Constance, Sugar Catherine A, Altshuler Lori L   The impact of neurocognitive impairment on occupational recovery of clinically stable patients with bipolar disorder: a prospective study Bipolar disorders, 2011; 13(4): 323-33.
Binder Elisabeth B, Jeffrey Newport D, Zach Elizabeth B, Smith Alicia K, Deveau Todd C, Altshuler Lori L, Cohen Lee S, Stowe Zachary N, Cubells Joseph F   A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort Journal of psychiatric research, 2010; 44(10): 640-6.
Altshuler Lori L, Abulseoud Osama A, Foland-Ross Lara, Bartzokis George, Chang Sean, Mintz Jim, Hellemann Gerhard, Vinters Harry V   Amygdala astrocyte reduction in subjects with major depressive disorder but not bipolar disorder Bipolar disorders, 2010; 12(5): 541-9.
Foland-Ross Lara C, Altshuler Lori L, Bookheimer Susan Y, Lieberman Matthew D, Townsend Jennifer, Penfold Conor, Moody Teena, Ahlf Kyle, Shen Jim K, Madsen Sarah K, Rasser Paul E, Toga Arthur W, Thompson Paul M   Amygdala reactivity in healthy adults is correlated with prefrontal cortical thickness The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(49): 16673-8.
Burt Vivien K, Bernstein Caryn, Rosenstein Wendy S, Altshuler Lori L   Bipolar disorder and pregnancy: maintaining psychiatric stability in the real world of obstetric and psychiatric complications The American journal of psychiatry, 2010; 167(8): 892-7.
Post Robert M, Altshuler Lori L, Frye Mark A, Suppes Trisha, Keck Paul E, McElroy Susan L, Leverich Gabriele S, Luckenbaugh David A, Rowe Michael, Pizzarello Scott, Kupka Ralph W, Grunze Heinz, Nolen Willem A   Complexity of pharmacologic treatment required for sustained improvement in outpatients with bipolar disorder The Journal of clinical psychiatry, 2010; 71(9): 1176-86; quiz 1252-3.
Post Robert M, Leverich Gabriele S, Kupka Ralph W, Keck Paul E, McElroy Susan L, Altshuler Lori L, Frye Mark A, Luckenbaugh David A, Rowe Michael, Grunze Heinz, Suppes Trisha, Nolen Willem A   Early-onset bipolar disorder and treatment delay are risk factors for poor outcome in adulthood The Journal of clinical psychiatry, 2010; 71(7): 864-72.
Altshuler Lori L, Kupka Ralph W, Hellemann Gerhard, Frye Mark A, Sugar Catherine A, McElroy Susan L, Nolen Willem A, Grunze Heinz, Leverich Gabriele S, Keck Paul E, Zermeno Melanie, Post Robert M, Suppes Trisha   Gender and depressive symptoms in 711 patients with bipolar disorder evaluated prospectively in the Stanley Foundation bipolar treatment outcome network The American journal of psychiatry, 2010; 167(6): 708-15.
Bartzokis George, Lu Po H, Tishler Todd A, Peters Douglas G, Kosenko Anastasia, Barrall Katherine A, Finn J Paul, Villablanca Pablo, Laub Gerhard, Altshuler Lori L, Geschwind Daniel H, Mintz Jim, Neely Elizabeth, Connor James R   Prevalent iron metabolism gene variants associated with increased brain ferritin iron in healthy older men Journal of Alzheimer's disease : JAD, 2010; 20(1): 333-41.
Townsend Jennifer, Bookheimer Susan Y, Foland-Ross Lara C, Sugar Catherine A, Altshuler Lori L   fMRI abnormalities in dorsolateral prefrontal cortex during a working memory task in manic, euthymic and depressed bipolar subjects Psychiatry research, 2010; 182(1): 22-9.
Townsend Jennifer D, Eberhart Nicole K, Bookheimer Susan Y, Eisenberger Naomi I, Foland-Ross Lara C, Cook Ian A, Sugar Catherine A, Altshuler Lori L   fMRI activation in the amygdala and the orbitofrontal cortex in unmedicated subjects with major depressive disorder Psychiatry research, 2010; 183(3): 209-17.
Hamilton Liberty S, Altshuler Lori L, Townsend Jennifer, Bookheimer Susan Y, Phillips Owen R, Fischer Jeffrey, Woods Roger P, Mazziotta John C, Toga Arthur W, Nuechterlein Keith H, Narr Katherine L   Alterations in functional activation in euthymic bipolar disorder and schizophrenia during a working memory task Human brain mapping, 2009; 30(12): 3958-69.
Schreibman Cohen Ayelet, Daley Melita, Siddarth Prabha, Levitt Jennifer, Loesch Ingrid K, Altshuler Lori, Ly Ronald, Shields W Donald, Gurbani Suresh, Caplan Rochelle   Amygdala volumes in childhood absence epilepsy Epilepsy & behavior : E&B, 2009; 16(3): 436-41.
Frye Mark A, Helleman Gerhard, McElroy Susan L, Altshuler Lori L, Black David O, Keck Paul E, Nolen Willem A, Kupka Ralph, Leverich Gabriele S, Grunze Heinz, Mintz Jim, Post Robert M, Suppes Trisha   Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression The American journal of psychiatry, 2009; 166(2): 164-72.
Altshuler Lori L, Post Robert M, Hellemann Gerhard, Leverich Gabriele S, Nolen Willem A, Frye Mark A, Keck Paul E, Kupka Ralph W, Grunze Heinz, McElroy Susan L, Sugar Catherine A, Suppes Trisha   Impact of antidepressant continuation after acute positive or partial treatment response for bipolar depression: a blinded, randomized study The Journal of clinical psychiatry, 2009; 70(4): 450-7.
Bartzokis George, Lu Po H, Stewart Stephanie B, Oluwadara Bolanle, Lucas Andrew J, Pantages Joanna, Pratt Erika, Sherin Jonathan E, Altshuler Lori L, Mintz Jim, Gitlin Michael J, Subotnik Kenneth L, Nuechterlein Keith H   In vivo evidence of differential impact of typical and atypical antipsychotics on intracortical myelin in adults with schizophrenia Schizophrenia research, 2009; 113(2-3): 322-31.
Suri Rita, Altshuler Lori L   No decision is without risk The Journal of clinical psychiatry, 2009; 70(9): 1319-20.
Altshuler Lori L, Bearden Carrie E, Green Michael F, van Gorp Wilfred, Mintz Jim   A relationship between neurocognitive impairment and functional impairment in bipolar disorder: a pilot study Psychiatry research, 2008; 157(1-3): 289-93.
Shivakumar Geetha, Bernstein Ira H, Suppes Trisha, Suppes Trisha, Keck Paul E, McElroy Susan L, Altshuler Lori L, Frye Mark A, Nolen Willem A, Kupka Ralph W, Grunze Heinze, Leverich Gabriele S, Mintz Jim, Post Robert M   Are bipolar mood symptoms affected by the phase of the menstrual cycle? Journal of women's health (2002), 2008; 17(3): 473-8.
Foland Lara C, Altshuler Lori L, Bookheimer Susan Y, Eisenberger Naomi, Townsend Jennifer, Thompson Paul M   Evidence for deficient modulation of amygdala response by prefrontal cortex in bipolar mania Psychiatry research, 2008; 162(1): 27-37.
Post Robert M, Luckenbaugh David A, Leverich Gabriele S, Altshuler Lori L, Frye Mark A, Suppes Trisha, Keck Paul E, McElroy Susan L, Nolen Willem A, Kupka Ralph, Grunze Heinz, Walden Joerg   Incidence of childhood-onset bipolar illness in the USA and Europe The British journal of psychiatry : the journal of mental science, 2008; 192(2): 150-1.
Foland Lara C, Altshuler Lori L, Sugar Catherine A, Lee Agatha D, Leow Alex D, Townsend Jennifer, Narr Katherine L, Asuncion Dina M, Toga Arthur W, Thompson Paul M   Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium Neuroreport, 2008; 19(2): 221-4.
Cardenas Jeffrey, Frye Mark A, Marusak Susan L, Levander Eric M, Chirichigno Jason W, Lewis Stryder, Nakelsky Shoshanna, Hwang Sun, Mintz Jim, Altshuler Lori L   Modal subcomponents of metabolic syndrome in patients with bipolar disorder Journal of affective disorders, 2008; 106(1-2): 91-7.
Altshuler Lori, Bookheimer Susan, Townsend Jennifer, Proenza Manuel A, Sabb Fred, Mintz Jim, Cohen Mark S   Regional brain changes in bipolar I depression: a functional magnetic resonance imaging study Bipolar disorders, 2008; 10(6): 708-17.
Suri Rita, Hellemann Gerhard, Cohen Lee, Aquino Ana, Altshuler Lori   Saliva estriol levels in women with and without prenatal antidepressant treatment Biological psychiatry, 2008; 64(6): 533-7.
Altshuler Lori L, Cohen Lee S, Vitonis Allison F, Faraone Stephen V, Harlow Bernard L, Suri Rita, Frieder Richard, Stowe Zachary N   The Pregnancy Depression Scale (PDS): a screening tool for depression in pregnancy Archives of women's mental health, 2008; 11(4): 277-85.
McElroy Susan L, Frye Mark A, Altshuler Lori L, Suppes Trisha, Hellemann Gerhard, Black David, Mintz Jim, Kupka Ralph, Nolen Willem, Leverich Gabriele S, Denicoff Kirk D, Post Robert M, Keck Paul E   A 24-week, randomized, controlled trial of adjunctive sibutramine versus topiramate in the treatment of weight gain in overweight or obese patients with bipolar disorders Bipolar disorders, 2007; 9(4): 426-34.
Frye Mark A, Grunze Heinz, Suppes Trisha, McElroy Susan L, Keck Paul E, Walden Jorge, Leverich Gabriele S, Altshuler Lori L, Nakelsky Shoshanna, Hwang Sun, Mintz Jim, Post Robert M   A placebo-controlled evaluation of adjunctive modafinil in the treatment of bipolar depression The American journal of psychiatry, 2007; 164(8): 1242-9.
Levander Eric, Frye Mark A, McElroy Susan, Suppes Trisha, Grunze Heinz, Nolen Willem A, Kupka Ralph, Keck Paul E, Leverich Gabriele S, Altshuler Lori L, Hwang Sun, Mintz Jim, Post Robert M   Alcoholism and anxiety in bipolar illness: differential lifetime anxiety comorbidity in bipolar I women with and without alcoholism Journal of affective disorders, 2007; 101(1-3): 211-7.
Bartzokis George, Tishler Todd A, Lu Po H, Villablanca Pablo, Altshuler Lori L, Carter Michele, Huang Danny, Edwards Nancy, Mintz Jim   Brain ferritin iron may influence age- and gender-related risks of neurodegeneration Neurobiology of aging, 2007; 28(3): 414-23.
Bartzokis George, Lu Po H, Nuechterlein Keith H, Gitlin Michael, Doi Clarissa, Edwards Nancy, Lieu Christopher, Altshuler Lori L, Mintz Jim   Differential effects of typical and atypical antipsychotics on brain myelination in schizophrenia Schizophrenia research, 2007; 93(1-3): 13-22.
Suri Rita, Altshuler Lori, Hellemann Gerhard, Burt Vivien K, Aquino Ana, Mintz Jim   Effects of antenatal depression and antidepressant treatment on gestational age at birth and risk of preterm birth The American journal of psychiatry, 2007; 164(8): 1206-13.
Rasgon Natalie L, Dunkin Jennifer, Fairbanks Lynn, Altshuler Lori L, Troung Co, Elman Shana, Wroolie Tonita E, Brunhuber Martina V, Rapkin Andrea   Estrogen and response to sertraline in postmenopausal women with major depressive disorder: a pilot study Journal of psychiatric research, 2007; 41(3-4): 338-43.
Altshuler Lori, Tekell Janet, Biswas Kousick, Kilbourne Amy M, Evans Denise, Tang Dengfang, Bauer Mark S   Executive function and employment status among veterans with bipolar disorder Psychiatric services (Washington, D.C.), 2007; 58(11): 1441-7.
Abulseoud Osama, Sane Natasha, Cozzolino Anthony, Kiriakos Lindsay, Mehra Vishal, Gitlin Michael, Masseling Susan, Whybrow Peter, Altshuler Lori L, Mintz Jim, Frye Mark A   Free T4 index and clinical outcome in patients with depression Journal of affective disorders, 2007; 100(1-3): 271-7.
Fan Alexander H, Frye Mark A, Hassell Susan J, Hwang Sun, Kiriakos Lindsay, Mintz Jim, Gitlin Michael J, Altshuler Lori L   Increased suicidality in mania complicated by alcoholism Psychiatry (Edgmont (Pa. : Township)), 2007; 4(4): 34-9.
McElroy Susan L, Suppes Trisha, Frye Mark A, Altshuler Lori L, Stanford Kevin, Martens Brian, Leverich Gabriele S, Post Robert M, Keck Paul E   Open-label aripiprazole in the treatment of acute bipolar depression: a prospective pilot trial Journal of affective disorders, 2007; 101(1-3): 275-81.
Suppes Trisha, Kelly Dorothy I, Keck Paul E, McElroy Susan L, Altshuler Lori L, Mintz Jim, Frye Mark A, Nolen Willem A, Luckenbaugh David A, Post Robert M, Leverich Gabriele S, Kupka Ralph W, Grunze Heinz   Quetiapine for the continuation treatment of bipolar depression: naturalistic prospective case series from the Stanley Bipolar Treatment Network International clinical psychopharmacology, 2007; 22(6): 376-81.
Leverich Gabriele S, Post Robert M, Keck Paul E, Altshuler Lori L, Frye Mark A, Kupka Ralph W, Nolen Willem A, Suppes Trisha, McElroy Susan L, Grunze Heinz, Denicoff Kirk, Moravec Maria K M, Luckenbaugh David   The poor prognosis of childhood-onset bipolar disorder The Journal of pediatrics, 2007; 150(5): 485-90.
Kupka Ralph W, Altshuler Lori L, Nolen Willem A, Suppes Trisha, Luckenbaugh David A, Leverich Gabriele S, Frye Mark A, Keck Paul E, McElroy Susan L, Grunze Heinz, Post Robert M   Three times more days depressed than manic or hypomanic in both bipolar I and bipolar II disorder Bipolar disorders, 2007; 9(5): 531-5.
Yaeger Deborah, Smith Healy G, Altshuler Lori L   Atypical antipsychotics in the treatment of schizophrenia during pregnancy and the postpartum The American journal of psychiatry, 2006; 163(12): 2064-70.
Bauer Mark S, McBride Linda, Williford William O, Glick Henry, Kinosian Bruce, Altshuler Lori, Beresford Thomas, Kilbourne Amy M, Sajatovic Martha, Sajatovic Martha   Collaborative care for bipolar disorder: Part II. Impact on clinical outcome, function, and costs Psychiatric services (Washington, D.C.), 2006; 57(7): 937-45.
Bauer Mark S, McBride Linda, Williford William O, Glick Henry, Kinosian Bruce, Altshuler Lori, Beresford Thomas, Kilbourne Amy M, Sajatovic Martha, Sajatovic Martha   Collaborative care for bipolar disorder: part I. Intervention and implementation in a randomized effectiveness trial Psychiatric services (Washington, D.C.), 2006; 57(7): 927-36.
Keck Paul E, Mintz Jim, McElroy Susan L, Freeman Marlene P, Suppes Trisha, Frye Mark A, Altshuler Lori L, Kupka Ralph, Nolen Willem A, Leverich Gabriele S, Denicoff Kirk D, Grunze Heinz, Duan Naihua, Post Robert M   Double-blind, randomized, placebo-controlled trials of ethyl-eicosapentanoate in the treatment of bipolar depression and rapid cycling bipolar disorder Biological psychiatry, 2006; 60(9): 1020-2.
Altshuler LL, Post R, Black DO, Nolen WA, Leverich G, Keck PE, Frye MA, Kupka R, McElroy SL, Grunze H, Kitchen C, Suppes T:   Lower switch rate in bipolar II than in bipolar I depressed patients treated adjunctively with second-generation antidepressants. A brief report, Am J Psychiatry, 2006; 163(2): 313-315.
Altshuler Lori L, Suppes Trisha, Black David O, Nolen Willem A, Leverich Gabriele, Keck Paul E, Frye Mark A, Kupka Ralph, McElroy Susan L, Grunze Heinz, Kitchen Christina M R, Post Robert   Lower switch rate in depressed patients with bipolar II than bipolar I disorder treated adjunctively with second-generation antidepressants The American journal of psychiatry, 2006; 163(2): 313-5.
Post RM, Altshuler LL, Leverich GS, Frye MA, Nolen WA, Kupka RW, Suppes T, McElroy S, Keck PE, Denicoff KD, Grunze H, Walden J, Kitchen CMR, Mintz J:   Mood switch in bipolar depression: Comparison of adjunctive venlafaxine, bupropion and sertraline, Brit J Psychiatry, 2006; 189: 124-131.
Post Robert M, Altshuler Lori L, Frye Mark A, Suppes Trisha, McElroy Susan, Keck Paul E, Leverich Gabriele S, Kupka Ralph, Nolen Willem A, Grunze Heinz   New findings from the Bipolar Collaborative Network: clinical implications for therapeutics Current psychiatry reports, 2006; 8(6): 489-97.
Cohen Lee S, Altshuler Lori L, Harlow Bernard L, Nonacs Ruta, Newport D Jeffrey, Viguera Adele C, Suri Rita, Burt Vivien K, Hendrick Victoria, Reminick Alison M, Loughead Ada, Vitonis Allison F, Stowe Zachary N   Relapse of major depression during pregnancy in women who maintain or discontinue antidepressant treatment JAMA : the journal of the American Medical Association, 2006; 295(5): 499-507.
Leverich Gabriele S, Altshuler Lori L, Frye Mark A, Suppes Trisha, McElroy Susan L, Keck Paul E, Kupka Ralph W, Denicoff Kirk D, Nolen Willem A, Grunze Heinz, Martinez Maria I, Post Robert M   Risk of switch in mood polarity to hypomania or mania in patients with bipolar depression during acute and continuation trials of venlafaxine, sertraline, and bupropion as adjuncts to mood stabilizers The American journal of psychiatry, 2006; 163(2): 232-9.
Altshuler Lori L, Post Robert M, Black David O, Keck Paul E, Nolen Willem A, Frye Mark A, Suppes Trisha, Grunze Heinz, Kupka Ralph W, Leverich Gabriele S, McElroy Susan L, Walden Joerg, Mintz Jim   Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder: results of a large, multisite study The Journal of clinical psychiatry, 2006; 67(10): 1551-60.
Keck Paul E, Corya Sara A, Altshuler Lori L, Ketter Terence A, McElroy Susan L, Case Michael, Briggs Susan D, Tohen Mauricio   Analyses of treatment-emergent mania with olanzapine/fluoxetine combination in the treatment of bipolar depression The Journal of clinical psychiatry, 2005; 66(5): 611-6.
Altshuler Lori L, Bookheimer Susan Y, Townsend Jennifer, Proenza Manuel A, Eisenberger Naomi, Sabb Fred, Mintz Jim, Cohen Mark S   Blunted activation in orbitofrontal cortex during mania: a functional magnetic resonance imaging study Biological psychiatry, 2005; 58(10): 763-9.
Kupka Ralph W, Luckenbaugh David A, Post Robert M, Suppes Trisha, Altshuler Lori L, Keck Paul E, Frye Mark A, Denicoff Kirk D, Grunze Heinz, Leverich Gabriele S, McElroy Susan L, Walden Jörg, Nolen Willem A   Comparison of rapid-cycling and non-rapid-cycling bipolar disorder based on prospective mood ratings in 539 outpatients The American journal of psychiatry, 2005; 162(7): 1273-80.
Altshuler Lori, Bookheimer Susan, Proenza Manuel A, Townsend Jennifer, Sabb Fred, Firestine Ann, Bartzokis George, Mintz Jim, Mazziotta John, Cohen Mark S   Increased amygdala activation during mania: a functional magnetic resonance imaging study The American journal of psychiatry, 2005; 162(6): 1211-3.
Rasgon Natalie L, Reynolds Margaret F, Elman Shana, Saad Mohammed, Frye Mark A, Bauer Michael, Altshuler Lori L   Longitudinal evaluation of reproductive function in women treated for bipolar disorder Journal of affective disorders, 2005; 89(1-3): 217-25.
Fenn Howard H, Bauer Mark S, Altshuler Lori, Alshuler Lori, Evans Denise R, Williford William O, Kilbourne Amy M, Beresford Thomas P, Kirk Gail, Stedman Margaret, Fiore Louis, Fiore Louis   Medical comorbidity and health-related quality of life in bipolar disorder across the adult age span Journal of affective disorders, 2005; 86(1): 47-60.
Suppes Trisha, Mintz Jim, McElroy Susan L, Altshuler Lori L, Kupka Ralph W, Frye Mark A, Keck Paul E, Nolen Willem A, Leverich Gabriele S, Grunze Heinz, Rush A John, Post Robert M   Mixed hypomania in 908 patients with bipolar disorder evaluated prospectively in the Stanley Foundation Bipolar Treatment Network: a sex-specific phenomenon Archives of general psychiatry, 2005; 62(10): 1089-96.
Bauer Michael, Rasgon Natalie, Grof Paul, Altshuler Lori, Gyulai Laszlo, Lapp Manfred, Glenn Tasha, Whybrow Peter C   Mood changes related to antidepressants: a longitudinal study of patients with bipolar disorder in a naturalistic setting Psychiatry research, 2005; 133(1): 73-80.
McElroy Susan L, Suppes Trisha, Keck Paul E, Black David, Frye Mark A, Altshuler Lori L, Nolen Willem A, Kupka Ralph W, Leverich Gabriele S, Walden Jorg, Grunze Heinz, Post Robert M   Open-label adjunctive zonisamide in the treatment of bipolar disorders: a prospective trial The Journal of clinical psychiatry, 2005; 66(5): 617-24.
McKowen James W, Frye Mark A, Altshuler Lori L, Gitlin Michael J   Patterns of alcohol consumption in bipolar patients comorbid for alcohol abuse or dependence Bipolar disorders, 2005; 7(4): 377-81.
Swann Alan C, Geller Barbara, Post Robert M, Altshuler Lori, Chang Kiki D, Delbello Melissa P, Reist Christopher, Juster Iver A   Practical Clues to Early Recognition of Bipolar Disorder: A Primary Care Approach Primary care companion to the Journal of clinical psychiatry, 2005; 7(1): 15-21.
Post Robert M, Altshuler Lori L, Frye Mark A, Suppes Trisha, McElroy Susan L, Keck Paul E, Leverich Gabriele S, Kupka Ralph, Nolen Willem A, Luckenbaugh David A, Walden Jorg, Grunze Heinz   Preliminary observations on the effectiveness of levetiracetam in the open adjunctive treatment of refractory bipolar disorder The Journal of clinical psychiatry, 2005; 66(3): 370-4.
Bauer Mark S, Altshuler Lori, Evans Denise R, Beresford Thomas, Williford William O, Hauger Richard, Hauger Richard   Prevalence and distinct correlates of anxiety, substance, and combined comorbidity in a multi-site public sector sample with bipolar disorder Journal of affective disorders, 2005; 85(3): 301-15.
Bartzokis George, Altshuler Lori   Reduced intracortical myelination in schizophrenia The American journal of psychiatry, 2005; 162(6): 1229-30.
Dunkin Jennifer, Rasgon Natalie, Wagner-Steh Kristi, David Steven, Altshuler Lori, Rapkin Andrea   Reproductive events modify the effects of estrogen replacement therapy on cognition in healthy postmenopausal women Psychoneuroendocrinology, 2005; 30(3): 284-96.
Rasgon Natalie L, Altshuler Lori L, Fairbanks Lynn, Elman Shana, Bitran Jose, Labarca Rodrigo, Saad Mohammed, Kupka Ralph, Nolen Willem A, Frye Mark A, Suppes Trisha, McElroy Susan L, Keck Paul E, Leverich Gabriele, Grunze Heinz, Walden Joerg, Post Robert, Mintz Jim   Reproductive function and risk for PCOS in women treated for bipolar disorder Bipolar disorders, 2005; 7(3): 246-59.
Suppes Trisha, Dennehy Ellen B, Hirschfeld Robert M A, Altshuler Lori L, Bowden Charles L, Calabrese Joseph R, Crismon M Lynn, Ketter Terence A, Sachs Gary S, Swann Alan C, Swann Alan C   The Texas implementation of medication algorithms: update to the algorithms for treatment of bipolar I disorder The Journal of clinical psychiatry, 2005; 66(7): 870-86.
State Rosanne C, Frye Mark A, Altshuler Lori L, Strober Michael, DeAntonio Mark, Hwang Sun, Mintz Jim   Chart review of the impact of attention-deficit/hyperactivity disorder comorbidity on response to lithium or divalproex sodium in adolescent mania The Journal of clinical psychiatry, 2004; 65(8): 1057-63.
Quanbeck Cameron D, Stone David C, Scott Charles L, McDermott Barbara E, Altshuler Lori L, Frye Mark A   Clinical and legal correlates of inmates with bipolar disorder at time of criminal arrest The Journal of clinical psychiatry, 2004; 65(2): 198-203.
Nolen Willem A, Luckenbaugh David A, Altshuler Lori L, Suppes Trisha, McElroy Susan L, Frye Mark A, Kupka Ralph W, Keck Paul E, Leverich Gabriele S, Post Robert M   Correlates of 1-year prospective outcome in bipolar disorder: results from the Stanley Foundation Bipolar Network The American journal of psychiatry, 2004; 161(8): 1447-54.
Suri Rita, Altshuler Lori A, Mintz Jim   Depression and the decision to abort The American journal of psychiatry, 2004; 161(8): 1502.
Yonkers Kimberly A, Wisner Katherine L, Stowe Zachary, Leibenluft Ellen, Cohen Lee, Miller Laura, Manber Rachel, Viguera Adele, Suppes Trisha, Altshuler Lori   Management of bipolar disorder during pregnancy and the postpartum period The American journal of psychiatry, 2004; 161(4): 608-20.
Altshuler Lori L, Ventura Joseph, van Gorp Wilfred G, Green Michael F, Theberge David C, Mintz Jim   Neurocognitive function in clinically stable men with bipolar I disorder or schizophrenia and normal control subjects Biological psychiatry, 2004; 56(8): 560-9.
Gitlin Michael, Altshuler Lori L, Frye Mark A, Suri Rita, Huynh Emily L, Fairbanks Lynn, Bauer Michael, Korenman Stanley   Peripheral thyroid hormones and response to selective serotonin reuptake inhibitors Journal of psychiatry & neuroscience : JPN, 2004; 29(5): 383-6.
Cohen Lee S, Altshuler Lori L, Stowe Zachary N, Faraone Stephen V   Reintroduction of antidepressant therapy across pregnancy in women who previously discontinued treatment. A preliminary retrospective study Psychotherapy and psychosomatics, 2004; 73(4): 255-8.
Frye Mark A, Gitlin Michael J, Altshuler Lori L   Unmet needs in bipolar depression Depression and anxiety, 2004; 19(4): 199-208.
Post Robert M, Leverich Gabriele S, Nolen Willem A, Kupka Ralph W, Altshuler Lori L, Frye Mark A, Suppes Trisha, McElroy Susan, Keck Paul, Grunze Heinze, Walden Jorg, Walden Jorg   A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network Bipolar disorders, 2003; 5(6): 396-406.
Post Robert M, Leverich Gabriele S, Altshuler Lori L, Frye Mark A, Suppes Trisha M, Keck Paul E, McElroy Susan L, Kupka Ralph, Nolen Willem A, Grunze Heinz, Walden Jorg   An overview of recent findings of the Stanley Foundation Bipolar Network (Part I) Bipolar disorders, 2003; 5(5): 310-9.
Frye Mark A, Altshuler Lori L, McElroy Susan L, Suppes Trisha, Keck Paul E, Denicoff Kirk, Nolen Willem A, Kupka Ralph, Leverich Gabriele S, Pollio Chad, Grunze Heinz, Walden Jorge, Post Robert M   Gender differences in prevalence, risk, and clinical correlates of alcoholism comorbidity in bipolar disorder The American journal of psychiatry, 2003; 160(5): 883-9.
Altshuler Lori, Suppes Trisha, Black David, Nolen Willem A, Keck Paul E, Frye Mark A, McElroy Susan, Kupka Ralph, Grunze Heinz, Walden Jörg, Leverich Gabrielle, Denicoff Kirk, Luckenbaugh David, Post Robert   Impact of antidepressant discontinuation after acute bipolar depression remission on rates of depressive relapse at 1-year follow-up The American journal of psychiatry, 2003; 160(7): 1252-62.
Quanbeck Cameron, Frye Mark, Altshuler Lori   Mania and the law in California: understanding the criminalization of the mentally ill The American journal of psychiatry, 2003; 160(7): 1245-50.
Post Robert M, Denicoff Kirk D, Leverich Gabriele S, Altshuler Lori L, Frye Mark A, Suppes Trisha M, Rush A John, Keck Paul E, McElroy Susan L, Luckenbaugh David A, Pollio Chad, Kupka Ralph, Nolen Willem A   Morbidity in 258 bipolar outpatients followed for 1 year with daily prospective ratings on the NIMH life chart method The Journal of clinical psychiatry, 2003; 64(6): 680-90; quiz 738-9.
Tohen Mauricio, Ketter Terence A, Zarate Carlos A, Suppes Trisha, Frye Mark, Altshuler Lori, Zajecka John, Schuh Leslie M, Risser Richard C, Brown Eileen, Baker Robert W   Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study The American journal of psychiatry, 2003; 160(7): 1263-71.
Hendrick Victoria, Stowe Zachary N, Altshuler Lori L, Hwang Sun, Lee Emily, Haynes Desiree   Placental passage of antidepressant medications The American journal of psychiatry, 2003; 160(5): 993-6.
Keck Paul E, McElroy Susan L, Havens Jennifer Rochussen, Altshuler Lori L, Nolen Willem A, Frye Mark A, Suppes Trisha, Denicoff Kirk D, Kupka Ralph, Leverich Gabrielle S, Rush A John, Post Robert M   Psychosis in bipolar disorder: phenomenology and impact on morbidity and course of illness Comprehensive psychiatry, 2003; 44(4): 263-9.

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