Gautam Chaudhuri M.D., M.B.B.S., Ph.D. | David Geffen School of Medicine at UCLA

Gautam Chaudhuri, M.D., M.B.B.S., Ph.D.

Contact Information:

Work Phone Number:

(310) 794-7274
310-206-2057
310-206-6575

Office Address:

Office
22-184 CHS
CAMPUS - 174017
CA
UNITED STATES

Work Address:

10833 Le Conte Avenue
LOS ANGELES, CA 90095
UNITED STATES

Work Email Address:

gchaudhuri@mednet.ucla.edu

Website:

Home Page.
Physician Profile.
Work.

Chair, and

Professor, Obstetrics and Gynecology

Professor, Molecular & Medical Pharmacology

Member, ACCESS Program: Dept. of Molecular & Medical Pharmacology

Internal Advisory Board

JCCC Signal Transduction and Therapeutics Program Area

CTSI

Research Education, Training, and Career Development Program (CTSI-ED)

Faculty, BWF-IT-MD

Center for Metabolic Disease Prevention

Molecular Toxicology IDP

A Short Biography:

Dr. Chaudhuri completed his MBBS from Calcutta University, India and his M.D. from the All-India Institute of Medical Sciences, India. He then obtained a Ph.D. in Pharmacology from London University under the mentorship of Professor Sir John Vane, who won the Nobel Prize in Medicine or Physiology in 1982. He subsequently completed his residency in Obstetrics and Gynecology from the State University of New York at Buffalo and joined UCLA to do a fellowship in Reproductive Endocrinology and Infertility. Following completion of this, he joined the department as an Assistant Professor. Since joining UCLA, he has published extensively on the action of sex steroids and nitric oxide. He, together with Lou Ignarro, Professor of Pharmacology at UCLA and a Nobel Laureate, was a member of one of the first groups to demonstrate that endothelium-derived relaxing factor is nitric oxide. He has in the past and continues at present to be supported by the NIH in the form of two RO1 grants. He has served for 4 years as a member of the Human Embryology and Development Review Group of the NIH program project review groups and for 4 years as a member of the Maternal and Child Health Committee of the NICHD. Recently, he was appointed as a member of the Advisory Council of the NICHD.

Awards and Honors:

SUNY Buffalo School of Medicine & Biomed Sciences
USC School of Medicine
Safdarjung Hospital

Publications:

Janzen Carla, Sen Suvajit, Cuevas Janis, Reddy Srinivasa T, Chaudhuri Gautam Protein phosphatase 2A promotes endothelial survival via stabilization of translational inhibitor 4E-BP1 following exposure to tumor necrosis factor-α. Arteriosclerosis, thrombosis, and vascular biology, 2011; 31(11): 2586-94.

Fung Camille, Evans Edward, Shin Don, Shin Bo-Chul, Zhao Yuanzi, Sankar Raman, Chaudhuri Gautam, Devaskar Sherin U Hypoxic-ischemic brain injury exacerbates neuronal apoptosis and precipitates spontaneous seizures in glucose transporter isoform 3 heterozygous null mice. Journal of neuroscience research, 2010; 88(15): 3386-98.

Pervin Shehla, Chaudhuri Gautam, Singh Rajan NO to breast: when, why and why not? Current pharmaceutical design, 2010; 16(4): 451-62.

van Nas, Guhathakurta, Wang, Yehya, Horvath, Zhang, Ingram-Drake, Chaudhuri, Schadt, Drake, Arnold, Lusis Elucidating the Role of Gonadal Hormones in Sexually Dimorphic Gene Co-Expression Networks. Endocrinology, 2008; .

Pervin Shehla, Singh Rajan, Chaudhuri Gautam Nitric oxide, N omega-hydroxy-L-arginine and breast cancer. Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, 2008; 19(2): 103-6.

Souter, Huang, Martinez-Maza, Crabb Breen, Decherney, Chaudhuri, Nathan Serum levels of soluble vascular cell adhesion molecule-1, tumor necrosis factor-alpha, and interleukin-6 in in vitro fertilization cycles. Fertility and sterility, 2008; .

Pervin Shehla, Tran An H, Zekavati Shaghayegh, Fukuto Jon M, Singh Rajan, Chaudhuri Gautam Increased susceptibility of breast cancer cells to stress mediated inhibition of protein synthesis. Cancer research, 2008; 68(12): 4862-74.

Chaudhuri Gautam Nuclear receptors and female reproduction: a tale of 3 scientists, Jensen, Gustafsson, and O'Malley. Reproductive sciences (Thousand Oaks, Calif.), 2008; 15(2): 110-20.

Friedlander Arthur H, Chaudhuri Gautam, Altman Lisa A past medical history of gestational diabetes: its medical significance and its dental implications. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2007; 103(2): 157-63.

Pervin Shehla, Singh Rajan, Hernandez Estebes, Wu Guoyao, Chaudhuri Gautam Nitric oxide in physiologic concentrations targets the translational machinery to increase the proliferation of human breast cancer cells: involvement of mammalian target of rapamycin/eIF4E pathway. Cancer research, 2007; 67(1): 289-99.

Hayashi Toshio, Esaki Teiji, Sumi Daigo, Mukherjee Tapan, Iguchi Akihisa, Chaudhuri Gautam Modulating role of estradiol on arginase II expression in hyperlipidemic rabbits as an atheroprotective mechanism. Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(27): 10485-90.

Souter Irene, Janzen Carla, Martinez-Maza Otoniel, Breen Elizabeth Crabb, Stanczyk Frank, Chaudhuri Gautam, Nathan Lauren Serum levels of soluble vascular cell adhesion molecule-1 are decreased in women receiving oral contraceptives compared with normally menstruating women: implications in atherosclerosis. Fertility and sterility, 2005; 83(5): 1480-8.

L�pez-Jaramillo Patricio, D�az Luis Alfonso, Pardo Alberto, Parra Gustavo, Jaimes Hermes, Chaudhuri Gautam Estrogen therapy increases plasma concentrations of nitric oxide metabolites in postmenopausal women but increases flow-mediated vasodilation only in younger women. Fertility and sterility, 2004; 82(6): 1550-5.

Pervin Shehla, Singh Rajan, Freije William A, Chaudhuri Gautam MKP-1-induced dephosphorylation of extracellular signal-regulated kinase is essential for triggering nitric oxide-induced apoptosis in human breast cancer cell lines: implications in breast cancer. Cancer research, 2003; 63(24): 8853-60.

Han Tae H, Qamirani Erion, Nelson Allyson G, Hyduke Daniel R, Chaudhuri Gautam, Kuo Lih, Liao James C Regulation of nitric oxide consumption by hypoxic red blood cells. Proceedings of the National Academy of Sciences of the United States of America, 2003; 100(21): 12504-9.

Pervin Shehla, Singh Rajan, Chaudhuri Gautam Nitric-oxide-induced Bax integration into the mitochondrial membrane commits MDA-MB-468 cells to apoptosis: essential role of Akt. Cancer research, 2003; 63(17): 5470-9.

Pervin S, Singh R, Chaudhuri G Nitric-oxide-induced Bax integration into the mitochondrial membrane commits MDA-MB-468 cells to apoptosis: essential role of Akt. Cancer research. , 2003; 63(17): 5470-9.

Mukherjee Tapan K, Nathan Lauren, Dinh Hillary, Reddy Srinivasa T, Chaudhuri Gautam 17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. The Journal of biological chemistry, 2003; 278(14): 11746-52.

Berman Jennifer R, Almeida Fernando G, Jolin Julie, Raz Shlomo, Chaudhuri Gautam, Gonzalez-Cadavid Nestor F Correlation of androgen receptors, aromatase, and 5-alpha reductase in the human vagina with menopausal status. Fertility and sterility, 2003; 79(4): 925-31.

Singh Rajan, Pervin Shehla, Chaudhuri Gautam Caspase-8-mediated BID cleavage and release of mitochondrial cytochrome c during Nomega-hydroxy-L-arginine-induced apoptosis in MDA-MB-468 cells. Antagonistic effects of L-ornithine. The Journal of biological chemistry, 2002; 277(40): 37630-6.

Mukherjee Tapan K, Dinh Hillary, Chaudhuri Gautam, Nathan Lauren Testosterone attenuates expression of vascular cell adhesion molecule-1 by conversion to estradiol by aromatase in endothelial cells: implications in atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America, 2002; 99(6): 4055-60.

Campisi Roxana, Nathan Lauren, Pampaloni Miguel Hernandez, Sch�der Heiko, Sayre James W, Chaudhuri Gautam, Schelbert Heinrich R Noninvasive assessment of coronary microcirculatory function in postmenopausal women and effects of short-term and long-term estrogen administration. Circulation, 2002; 105(4): 425-30.

Nathan L, Pervin S, Singh R, Rosenfeld M, Chaudhuri G Estradiol inhibits leukocyte adhesion and transendothelial migration in rabbits in vivo : possible mechanisms for gender differences in atherosclerosis. Circulation research. , 1999; 85(4): 377-85.

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