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Stephen Marder, M.D.
Contact Information:
Work Phone Number:
(800) 825-9989
Mailing Address:
UCLA Psychr & Biobehav Sci / VA Greater LA Healthcare Sys BOX 951667, 11301 Wilshire Blvd. MIRECC Bldg 210, Rm 130 Los Angeles, CA 90073 UNITED STATES
Director,
Section on Psychosis
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Professor,
Psychiatry and Biobehavioral Sciences
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Professor in Residence,
Semel Institute for Neuroscience and Human Behavior
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Member,
Adult Psychiatry
CTSI
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Awards and Honors:
University of Southern California
Denver General Hospital, Denver, CO
National Institute of Mental Health
Detailed Biography:
Stephen R. Marder, M.D. received his A.B. from the University of Pennsylvania and his M.D. from the State University of New York at Buffalo. After an internship at Denver General Hospital he completed a residency at the University of Southern California. From 1975 to 1977 he was a Clinical Associate in the Biological Psychiatry Branch at the National Institute of Mental Health. In 1977 he joined the staff at the Brentwood VA Medical Center and the faculty at UCLA.
Dr. Marder's research has focused on the drug treatment of schizophrenia and the pharmacology of antipsychotic drugs. He has authored or co-authored more than 200 journal articles and chapters based on research. The Schizophrenia Research Unit that he developed together with the late Theodore Van Putten has been an important site for training a number of psychiatrists who developed careers in research. He has been a Professor and Vice Chair of the Department of Psychiatry at UCLA since 1991. He is currently the Director of the VISN 22 Mental Illness Research, Education Clinical Center (MIRECC) for the Department of Veterans Affairs and the Director of the Section on Psychosis at the UCLA Neuropsychiatric Institute.
Publications:
Sherer Eric A, Sale Mark E, Pollock Bruce G, Belani Chandra P, Egorin Merrill J, Ivy Percy S, Lieberman Jeffrey A, Manuck Stephen B, Marder Stephen R, Muldoon Matthew F, Scher Howard I, Solit David B, Bies Robert R
Application of a single-objective, hybrid genetic algorithm approach
to pharmacokinetic model building.
Journal of pharmacokinetics and pharmacodynamics,
2012; 39(4):
393-414.
Keefe Richard S E, Vinogradov Sophia, Medalia Alice, Buckley Peter F, Caroff Stanley N, D'Souza Deepak C, Harvey Phillip D, Graham Karen A, Hamer Robert M, Marder Stephen M, Miller Del D, Olson Stephen J, Patel Jayendra K, Velligan Dawn, Walker Trina M, Haim Adam J, Stroup T Scott
Feasibility and pilot efficacy results from the multisite cognitive
remediation in the schizophrenia trials network (CRSTN) randomized
controlled trial.
The Journal of clinical psychiatry,
2012; 73(7):
1016-22.
Velligan Dawn I, Rubin Maureen, Fredrick Megan M, Mintz Jim, Nuechterlein Keith H, Schooler Nina R, Jaeger Judith, Peters Nancy M, Buller Raimund, Marder Stephen R, Dube Sanjay
The cultural adaptability of intermediate measures of functional
outcome in schizophrenia.
Schizophrenia bulletin,
2012; 38(3):
630-41.
Javitt Daniel C, Buchanan Robert W, Keefe Richard S E, Kern Robert, McMahon Robert P, Green Michael F, Lieberman Jeffrey, Goff Donald C, Csernansky John G, McEvoy Joseph P, Jarskog Fred, Seidman Larry J, Gold James M, Kimhy David, Nolan Karen S, Barch Deanna S, Ball M Patricia, Robinson James, Marder Stephen R
Effect of the neuroprotective peptide davunetide (AL-108) on cognition
and functional capacity in schizophrenia.
Schizophrenia research,
2012; 136(1-3):
25-31.
Wessels Alette M, Bies Robert R, Pollock Bruce G, Schneider Lon S, Lieberman Jeffrey A, Stroup Scott, Li Claire H, Coley Kim, Kirshner Margaret M, Marder Stephen R
Population pharmacokinetic modeling of ziprasidone in patients with
schizophrenia from the CATIE study.
Journal of clinical pharmacology,
2011; 51(11):
1587-91.
Marder Stephen R, Roth Bryan, Sullivan Patrick F, Scolnick Edward M, Nestler Eric J, Geyer Mark A, Welnberger Daniel R, Karayiorgou Maria, Guidotti Alessandro, Gingrich Jay, Akbarian Schahram, Buchanan Robert W, Lieberman Jeffrey A, Conn P Jeffrey, Haggarty Stephen J, Law Amanda J, Campbell Brian, Krystal John H, Moghaddam Bita, Sawa Akira, Saw Akira, Caron Marc G, George Susan R, Allen John A, Solis Michelle
Advancing drug discovery for schizophrenia.
Annals of the New York Academy of Sciences,
2011; 1236(6):
30-43.
Green Michael F, Schooler Nina R, Kern Robert S, Frese Fred J, Granberry Wendy, Harvey Philip D, Karson Craig N, Peters Nancy, Stewart Michelle, Seidman Larry J, Sonnenberg John, Stone William S, Walling David, Stover Ellen, Marder Stephen R
Evaluation of functionally meaningful measures for clinical trials of
cognition enhancement in schizophrenia.
The American journal of psychiatry,
2011; 168(4):
400-7.
Young Alexander S, Niv Noosha, Chinman Matthew, Dixon Lisa, Eisen Susan V, Fischer Ellen P, Smith Jeffrey, Valenstein Marcia, Marder Stephen R, Owen Richard R
Routine outcomes monitoring to support improving care for
schizophrenia: report from the VA Mental Health QUERI.
Community mental health journal,
2011; 47(2):
123-35.
Buchanan Robert W, Keefe Richard S E, Lieberman Jeffrey A, Barch Deanna M, Csernansky John G, Goff Donald C, Gold James M, Green Michael F, Jarskog L Fredrik, Javitt Daniel C, Kimhy David, Kraus Michael S, McEvoy Joseph P, Mesholam-Gately Raquelle I, Seidman Larry J, Ball M Patricia, McMahon Robert P, Kern Robert S, Robinson James, Marder Stephen R
A randomized clinical trial of MK-0777 for the treatment of cognitive
impairments in people with schizophrenia.
Biological psychiatry,
2011; 69(5):
442-9.
Kern Robert S, Gold James M, Dickinson Dwight, Green Michael F, Nuechterlein Keith H, Baade Lyle E, Keefe Richard S E, Mesholam-Gately Raquelle I, Seidman Larry J, Lee Cathy, Sugar Catherine A, Marder Stephen R
The MCCB impairment profile for schizophrenia outpatients: results
from the MATRICS psychometric and standardization study.
Schizophrenia research,
2011; 126(1-3):
124-31.
Marder Stephen R, Sorsaburu Sebastian, Dunayevich Eduardo, Karagianis Jamie L, Dawe Ian C, Falk Deborah M, Dellva Mary Anne, Carlson Janice L, Cavazzoni Patrizia A, Baker Robert W
Case reports of postmarketing adverse event experiences with
olanzapine intramuscular treatment in patients with agitation.
The Journal of clinical psychiatry,
2010; 71(4):
433-41.
Jin Yuyan, Pollock Bruce G, Coley Kim, Miller Del, Marder Stephen R, Florian Jeff, Schneider Lon, Lieberman Jeffrey, Kirshner Margaret, Bies Robert R
Population pharmacokinetics of perphenazine in schizophrenia patients
from CATIE: impact of race and smoking.
Journal of clinical pharmacology,
2010; 50(1):
73-80.
Kane John M, Correll Christoph U, Goff Donald C, Kirkpatrick Brian, Marder Stephen R, Vester-Blokland Estelle, Sun Wei, Carson William H, Pikalov Andrei, Assunção-Talbott Sheila
A multicenter, randomized, double-blind, placebo-controlled, 16-week
study of adjunctive aripiprazole for schizophrenia or schizoaffective
disorder inadequately treated with quetiapine or risperidone
monotherapy.
The Journal of clinical psychiatry,
2009; 70(10):
1348-57.
Krystal John H, Carter Cameron S, Geschwind Daniel, Manji Husseini K, March John S, Nestler Eric J, Zubieta Jon-Kar, Charney Dennis S, Goldman David, Gur Raquel E, Lieberman Jeffrey A, Roy-Byrne Peter, Rubinow David R, Anderson Stewart A, Barondes Samuel, Berman Karen F, Blair James, Braff David L, Brown E Sherwood, Calabrese Joseph R, Carlezon William A, Cook Edwin H, Davidson Richard J, Davis Michael, Desimone Robert, Drevets Wayne C, Duman Ronald S, Essock Susan M, Faraone Stephen V, Freedman Robert, Friston Karl J, Gelernter Joel, Geller Barbara, Gill Michael, Gould Elizabeth, Grace Anthony A, Grillon Christian, Gueorguieva Ralitza, Hariri Ahmad R, Innis Robert B, Jones Edward G, Kleinman Joel E, Koob George F, Krystal Andrew D, Leibenluft Ellen, Levinson Douglas F, Levitt Pat R, Lewis David A, Liberzon Israel, Lipska Barbara K, Marder Stephen R, Markou Athina, Mason Graeme F, McDougle Christopher J, McEwen Bruce S, McMahon Francis J, Meaney Michael J, Meltzer Herbert Y, Merikangas Kathleen R, Meyer-Lindenberg Andreas, Mirnics Károly, Monteggia Lisa M, Neumeister Alexander, O'Brien Charles P, Owen Michael J, Pine Daniel S, Rapoport Judith L, Rauch Scott L, Robbins Trevor W, Rosenbaum Jerrold F, Rosenberg David R, Ross Christopher A, Rush A John, Sackeim Harold A, Sanacora Gerard, Schatzberg Alan F, Shaham Yavin, Siever Larry J, Sunderland Trey, Tecott Laurence H, Thase Michael E, Todd Richard D, Weissman Myrna M, Yehuda Rachel, Yoshikawa Takeo, Young Elizabeth A, McCandless R
It is time to take a stand for medical research and against terrorism
targeting medical scientists.
Biological psychiatry,
2008; 63(8):
725-7.
Green Michael F, Nuechterlein Keith H, Kern Robert S, Baade Lyle E, Fenton Wayne S, Gold James M, Keefe Richard S E, Mesholam-Gately Raquelle, Seidman Larry J, Stover Ellen, Marder Stephen R
Functional co-primary measures for clinical trials in schizophrenia:
results from the MATRICS Psychometric and Standardization Study.
The American journal of psychiatry,
2008; 165(2):
221-8.
Bigos Kristin L, Pollock Bruce G, Coley Kim C, Miller Del D, Marder Stephen R, Aravagiri Manickam, Kirshner Margaret A, Schneider Lon S, Bies Robert R
Sex, race, and smoking impact olanzapine exposure.
Journal of clinical pharmacology,
2008; 48(2):
157-65.
Nuechterlein Keith H, Green Michael F, Kern Robert S, Baade Lyle E, Barch Deanna M, Cohen Jonathan D, Essock Susan, Fenton Wayne S, Frese Frederick J, Gold James M, Goldberg Terry, Heaton Robert K, Keefe Richard S E, Kraemer Helena, Mesholam-Gately Raquelle, Seidman Larry J, Stover Ellen, Weinberger Daniel R, Young Alexander S, Zalcman Steven, Marder Stephen R
The MATRICS Consensus Cognitive Battery, part 1: test selection,
reliability, and validity.
The American journal of psychiatry,
2008; 165(2):
203-13.
Kern Robert S, Nuechterlein Keith H, Green Michael F, Baade Lyle E, Fenton Wayne S, Gold James M, Keefe Richard S E, Mesholam-Gately Raquelle, Mintz Jim, Seidman Larry J, Stover Ellen, Marder Stephen R
The MATRICS Consensus Cognitive Battery, part 2: co-norming and
standardization.
The American journal of psychiatry,
2008; 165(2):
214-20.
Foerde Karin, Poldrack Russell A, Khan Barbara J, Sabb Fred W, Bookheimer Susan Y, Bilder Robert M, Guthrie Don, Granholm Eric, Nuechterlein Keith H, Marder Stephen R, Asarnow Robert F
Selective corticostriatal dysfunction in schizophrenia: examination of
motor and cognitive skill learning.
Neuropsychology,
2008; 22(1):
100-9.
Moore Troy A, Buchanan Robert W, Buckley Peter F, Chiles John A, Conley Robert R, Crismon M Lynn, Essock Susan M, Finnerty Molly, Marder Stephen R, Miller Del D, McEvoy Joseph P, Robinson Delbert G, Schooler Nina R, Shon Steven P, Stroup T Scott, Miller Alexander L
The Texas Medication Algorithm Project antipsychotic algorithm for
schizophrenia: 2006 update.
The Journal of clinical psychiatry,
2007; 68(11):
1751-62.
Sergi Mark J, Green Michael F, Widmark Clifford, Reist Christopher, Erhart Stephen, Braff David L, Kee Kimmy S, Marder Stephen R, Mintz Jim
Social cognition [corrected] and neurocognition: effects of
risperidone, olanzapine, and haloperidol.
The American journal of psychiatry,
2007; 164(10):
1585-92.
Wynn Jonathan K, Green Michael F, Sprock Joyce, Light Gregory A, Widmark Clifford, Reist Christopher, Erhart Stephen, Marder Stephen R, Mintz Jim, Braff David L
Effects of olanzapine, risperidone and haloperidol on prepulse
inhibition in schizophrenia patients: a double-blind, randomized
controlled trial.
Schizophrenia research,
2007; 95(1-3):
134-42.
Davis John M, Marder Stephen R, Tamminga Carol A
Switch or stay?
The American journal of psychiatry,
2006; 163(12):
2032-3.
Mohr Penny E, Cheng C Michael, Claxton Karl, Conley Robert R, Feldman Jacob J, Hargreaves William A, Lehman Anthony F, Lenert Leslie A, Mahmoud Ramy, Marder Stephen R, Neumann Peter J
The heterogeneity of schizophrenia in disease states.
Schizophrenia research,
2004; 71(1):
83-95.
Green Michael F, Nuechterlein Keith H, Gold James M, Barch Deanna M, Cohen Jonathan, Essock Susan, Fenton Wayne S, Frese Fred, Goldberg Terry E, Heaton Robert K, Keefe Richard S E, Kern Robert S, Kraemer Helena, Stover Ellen, Weinberger Daniel R, Zalcman Steven, Marder Stephen R
Approaching a consensus cognitive battery for clinical trials in
schizophrenia: the NIMH-MATRICS conference to select cognitive domains
and test criteria.
Biological psychiatry,
2004; 56(5):
301-7.
Marder Stephen R, Essock Susan M, Miller Alexander L, Buchanan Robert W, Casey Daniel E, Davis John M, Kane John M, Lieberman Jeffrey A, Schooler Nina R, Covell Nancy, Stroup Scott, Weissman Ellen M, Wirshing Donna A, Hall Catherine S, Pogach Leonard, Pi-Sunyer Xavier, Bigger J Thomas, Friedman Alan, Kleinberg David, Yevich Steven J, Davis Bonnie, Shon Steven
Physical health monitoring of patients with schizophrenia.
The American journal of psychiatry,
2004; 161(8):
1334-49.
Miller Alexander L, Hall Catherine S, Buchanan Robert W, Buckley Peter F, Chiles John A, Conley Robert R, Crismon M Lynn, Ereshefsky Larry, Essock Susan M, Finnerty Molly, Marder Stephen R, Miller Del D, McEvoy Joseph P, Rush A John, Saeed Sy A, Schooler Nina R, Shon Steven P, Stroup Scott, Tarin-Godoy Bernardo
The Texas Medication Algorithm Project antipsychotic algorithm for
schizophrenia: 2003 update.
The Journal of clinical psychiatry,
2004; 65(4):
500-8.
Potkin Steven G, Saha Anutosh R, Kujawa Mary J, Carson William H, Ali Mirza, Stock Elyse, Stringfellow Joseph, Ingenito Gary, Marder Stephen R
Aripiprazole, an antipsychotic with a novel mechanism of action, and
risperidone vs placebo in patients with schizophrenia and
schizoaffective disorder.
Archives of general psychiatry,
2003; 60(7):
681-90.
Marder Stephen R, McQuade Robert D, Stock Elyse, Kaplita Stephen, Marcus Ronald, Safferman Allan Z, Saha Anutosh, Ali Mirza, Iwamoto Taro
Aripiprazole in the treatment of schizophrenia: safety and
tolerability in short-term, placebo-controlled trials.
Schizophrenia research,
2003; 61(2-3):
123-36.
Merlo Marco C G, Hofer Helene, Gekle Walter, Berger Gregor, Ventura Joseph, Panhuber Ingrid, Latour Gabriela, Marder Stephen R
Risperidone, 2 mg/day vs. 4 mg/day, in first-episode, acutely
psychotic patients: treatment efficacy and effects on fine motor
functioning.
The Journal of clinical psychiatry,
2002; 63(10):
885-91.
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