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Andrew Saxon, M.D.

Contact Information:

Work Phone Number:

(310) 825-7921

Mailing Address:

UCLA Med-CIA
BOX 951680, 37-131 CHS
Los Angeles, CA 90095
UNITED STATES

Work Email Address:

asaxon@mednet.ucla.edu

Website:

Work.

Executive Director, Food and Drug Allergy Care Center

Physician, Clinical Immunology and Allergy

Professor Emeritus, Medicine

Clinical Immunology and Allergy


Awards and Honors:

Harbor - UCLA Medical Center
Harbor - UCLA Medical Center
UCLA School of Medicine

Publications:

Lin Erina, Saxon Andrew, Riedl Marc   Penicillin allergy: value of including amoxicillin as a determinant in penicillin skin testing. International archives of allergy and immunology, 2010; 152(4): 313-8.
Behnecke Anne, Li Wei, Chen Ling, Saxon Andrew, Zhang Ke   IgE-mediated allergen gene vaccine platform targeting human antigen-presenting cells through the high-affinity IgE receptor. The Journal of allergy and clinical immunology, 2009; 124(1): 108-13.
Riedl Marc A, Saxon Andrew, Diaz-Sanchez David   Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway. Clinical immunology (Orlando, Fla.), 2009; 130(3): 244-51.
Zhang Ke, Behnecke Anne, Li Wei, Saxon Andrew   A novel multi-potential dendritic cell targeted gene vaccination platform; application to food allergy and beyond. Arbeiten aus dem Paul-Ehrlich-Institut (Bundesinstitut für Impfstoffe und biomedizinische Arzneimittel) Langen/Hessen, 2009; 96(2): 338-47; discussion 348.
Saxon Andrew   "Who-mab's on first and what-cept's on second. I don't know--third base". Clinical immunology (Orlando, Fla.), 2008; 127(3): 267.
Saxon Andrew, Kepley Chris, Zhang Ke   "Accentuate the negative, eliminate the positive": engineering allergy therapeutics to block allergic reactivity through negative signaling. The Journal of allergy and clinical immunology, 2008; 121(2): 320-5.
Mertsching Elisabeth, Bafetti Lisa, Hess Henry, Perper Stuart, Giza Keith, Allen Lisa Chan, Negrou Ella, Hathaway Karen, Hopp Jennifer, Chung Julie, Perret Daniel, Shields Michael, Saxon Andrew, Kehry Marilyn R   A mouse Fcgamma-Fcepsilon protein that inhibits mast cells through activation of FcgammaRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases. The Journal of allergy and clinical immunology, 2008; 121(2): 441-447.e5.
Allen Lisa Chan, Kepley Christopher L, Saxon Andrew, Zhang Ke   Modifications to an Fcgamma-Fcvarepsilon fusion protein alter its effectiveness in the inhibition of FcvarepsilonRI-mediated functions. The Journal of allergy and clinical immunology, 2007; 120(2): 462-8.
Zhang Ke, Zhu Daocheng, Kepley Christopher, Terada Tetsuya, Saxon Andrew   Chimeric human fcgamma-allergen fusion proteins in the prevention of allergy. Immunology and allergy clinics of North America, 2007; 27(1): 93-103.
Hardin Bryan D, Kelman Bruce J, Saxon Andrew   Nondisclosure of conflicts of interest is perilous to the advancement of science. The Journal of allergy and clinical immunology, 2007; 119(1): 256-7.
Terada Tetsuya, Zhang Ke, Belperio John, Londhe Vedang, Saxon Andrew   A chimeric human-cat Fcgamma-Fel d1 fusion protein inhibits systemic, pulmonary, and cutaneous allergic reactivity to intratracheal challenge in mice sensitized to Fel d1, the major cat allergen. Clinical immunology (Orlando, Fla.), 2006; 120(1): 45-56.
Saxon Andrew, Zhu Daocheng, Zhang Ke, Chan Lisa A, Kepley Christopher L   Recent advances in the use of genetically engineered negative signaling molecules to treat allergic diseases. Arbeiten aus dem Paul-Ehrlich-Institut (Bundesamt für Sera und Impfstoffe) zu Frankfurt a.M, 2006; 26(95): 223-31; discussion 231-3.
Bush Robert K, Portnoy Jay M, Saxon Andrew, Terr Abba I, Wood Robert A   The medical effects of mold exposure. The Journal of allergy and clinical immunology, 2006; 117(2): 326-33.
Riedl Marc A, Landaw Elliot M, Saxon Andrew, Diaz-Sanchez David   Initial high-dose nasal allergen exposure prevents allergic sensitization to a neoantigen. Journal of immunology (Baltimore, Md. : 1950), 2005; 174(11): 7440-5.
Yamada Takechiyo, Zhang Ke, Yamada Akiko, Zhu Daocheng, Saxon Andrew   B lymphocyte stimulator activates p38 mitogen-activated protein kinase in human Ig class switch recombination. American journal of respiratory cell and molecular biology, 2005; 32(5): 388-94.
Zhu Daocheng, Kepley Christopher L, Zhang Ke, Terada Tetsuya, Yamada Takechiyo, Saxon Andrew   A chimeric human-cat fusion protein blocks cat-induced allergy. Nature medicine, 2005; 11(4): 446-9.
Saxon Andrew, Diaz-Sanchez David   Air pollution and allergy: you are what you breathe. Nature immunology, 2005; 6(3): 223-6.
Saxon Andrew, Zhu Daocheng, Zhang Ke, Allen Lisa Chan, Kepley Christopher L   Genetically engineered negative signaling molecules in the immunomodulation of allergic diseases. Current opinion in allergy and clinical immunology, 2004; 4(6): 563-8.
Corren Jonathan, Diaz-Sanchez David, Saxon Andrew, Deniz Yamo, Reimann James, Sinclair Don, Davancaze Teresa, Adelman Daniel   Effects of omalizumab, a humanized monoclonal anti-IgE antibody, on nasal reactivity to allergen and local IgE synthesis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004; 93(3): 243-8.
Zhang Ke, Kepley Christopher L, Terada Tetsuya, Zhu Daocheng, Perez Hector, Saxon Andrew   Inhibition of allergen-specific IgE reactivity by a human Ig Fcgamma-Fcepsilon bifunctional fusion protein. The Journal of allergy and clinical immunology, 2004; 114(2): 321-7.
Saxon Andrew, Hardin Bryan D, Kelman Bruce J   Exposure-dose-response: critical considerations in toxicology and immunology alike. The Journal of allergy and clinical immunology, 2004; 114(1): 207; author reply 207-8.
Saxon Andrew, Macy Eric   Cross-reactivity and sulfonamide antibiotics. The New England journal of medicine, 2004; 350(3): 302-3; author reply 302-3.
Saxon Andrew   Primary immunodeficiencies: rare disorders in the era of global medicine. Clinical immunology (Orlando, Fla.), 2003; 109(3): 249.
Bastain Theresa M, Gilliland Frank D, Li Yu Fen, Saxon Andrew, Diaz-Sanchez David   Intraindividual reproducibility of nasal allergic responses to diesel exhaust particles indicates a susceptible phenotype. Clinical immunology (Orlando, Fla.), 2003; 109(2): 130-6.
Kepley Christopher L, Zhang Ke, Zhu Daocheng, Saxon Andrew   FcepsilonRI-FcgammaRII coaggregation inhibits IL-16 production from human Langerhans-like dendritic cells. Clinical immunology (Orlando, Fla.), 2003; 108(2): 89-94.
Yamada Takechiyo, Zhu Daocheng, Zhang Ke, Saxon Andrew   Inhibition of interleukin-4-induced class switch recombination by a human immunoglobulin Fc gamma-Fc epsilon chimeric protein. The Journal of biological chemistry, 2003; 278(35): 32818-24.
Zhang Ke, Zhang Ling, Zhu Daocheng, Bae David, Nel Andre, Saxon Andrew   CD40-mediated p38 mitogen-activated protein kinase activation is required for immunoglobulin class switch recombination to IgE. The Journal of allergy and clinical immunology, 2002; 110(3): 421-8.
Yamada Takechiyo, Zhu Daocheng, Saxon Andrew, Zhang Ke   CD45 controls interleukin-4-mediated IgE class switch recombination in human B cells through its function as a Janus kinase phosphatase. The Journal of biological chemistry, 2002; 277(32): 28830-5.
Zhu Daocheng, Kepley Christopher L, Zhang Min, Zhang Ke, Saxon Andrew   A novel human immunoglobulin Fc gamma Fc epsilon bifunctional fusion protein inhibits Fc epsilon RI-mediated degranulation. Nature medicine, 2002; 8(5): 518-21.
Devouassoux Gilles, Saxon Andrew, Metcalfe Dean D, Prussin Calman, Colomb Maurice G, Brambilla Christian, Diaz-Sanchez David   Chemical constituents of diesel exhaust particles induce IL-4 production and histamine release by human basophils. The Journal of allergy and clinical immunology, 2002; 109(5): 847-53.
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