Publications:
A selected list of publications:
Dubinsky Marla C, Kugathasan Subra, Kwon Soonil, Haritunians Talin, Wrobel Iwona, Wahbeh Ghassan, Quiros Antonio, Bahar Ron, Silber Gary, Farrior Sharmayne, Stephens Michael, Teleten Nick, Panikkath Deepa, Ippoliti Andrew, Vasiliauskas Eric, Fleshner Phillip, Williams Chadwick, Landers Carol, Rotter Jerome I, Targan Stephan R, Taylor Kent D, McGovern Dermot P B
Multidimensional Prognostic Risk Assessment Identifies Association
Between IL12B Variation and Surgery in Crohn's Disease
Inflammatory bowel diseases,
2013;
.
Mahadevan Uma, Wolf Douglas C, Dubinsky Marla, Cortot Antoine, Lee Scott D, Siegel Corey A, Ullman Thomas, Glover Sarah, Valentine John F, Rubin David T, Miller Jocelyn, Abreu Maria T
Placental transfer of anti-tumor necrosis factor agents in pregnant
patients with inflammatory bowel disease
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association,
2013; 11(3):
286-92; quiz e24.
Le Quy, Melmed Gil, Dubinsky Marla, McGovern Dermot, Vasiliauskas Eric A, Murrell Zuri, Ippoliti Andrew, Shih David, Kaur Manreet, Targan Stephan, Fleshner Phillip
Surgical outcome of ileal pouch-anal anastomosis when used
intentionally for well-defined Crohn's disease
Inflammatory bowel diseases,
2013; 19(1):
30-6.
Iliev Iliyan D, Funari Vincent A, Taylor Kent D, Nguyen Quoclinh, Reyes Christopher N, Strom Samuel P, Brown Jordan, Becker Courtney A, Fleshner Phillip R, Dubinsky Marla, Rotter Jerome I, Wang Hanlin L, McGovern Dermot P B, Brown Gordon D, Underhill David M
Interactions between commensal fungi and the C-type lectin receptor
Dectin-1 influence colitis
Science (New York, N.Y.),
2012; 336(6086):
1314-7.
Hyams Jeffrey S, Griffiths Anne, Markowitz James, Baldassano Robert N, Faubion William A, Colletti Richard B, Dubinsky Marla, Kierkus Jaroslaw, Rosh Joel, Wang Yaqin, Huang Bidan, Bittle Barry, Marshall Michael, Lazar Andreas
Safety and efficacy of adalimumab for moderate to severe Crohn's
disease in children
Gastroenterology,
2012; 143(2):
365-74.e2.
Talley Nicholas J, Abreu Maria T, Achkar Jean-Paul, Bernstein Charles N, Dubinsky Marla C, Hanauer Stephen B, Kane Sunanda V, Sandborn William J, Ullman Thomas A, Moayyedi Paul, Moayyedi Paul
An evidence-based systematic review on medical therapies for
inflammatory bowel disease
The American journal of gastroenterology,
2011; 106 Suppl 1(6):
S2-25; quiz S26.
Lichtenstein Gary R, Targan Stephan R, Dubinsky Marla C, Rotter Jerome I, Barken Derren M, Princen Fred, Carroll Susan, Brown Michelle, Stachelski Jordan, Chuang Emil, Landers Carol J, Stempak Joanne M, Singh Sharat, Silverberg Mark S
Combination of genetic and quantitative serological immune markers are
associated with complicated Crohn's disease behavior
Inflammatory bowel diseases,
2011; 17(12):
2488-96.
Turner Dan, Travis Simon P L, Griffiths Anne M, Ruemmele Frank M, Levine Arie, Benchimol Eric I, Dubinsky Marla, Alex George, Baldassano Robert N, Langer Jacob C, Shamberger Robert, Hyams Jeffrey S, Cucchiara Salvatore, Bousvaros Athos, Escher Johanna C, Markowitz James, Wilson David C, van Assche Gert, Russell Richard K, Russell Richard K, Russell Richard K
Consensus for managing acute severe ulcerative colitis in children: a
systematic review and joint statement from ECCO, ESPGHAN, and the
Porto IBD Working Group of ESPGHAN
The American journal of gastroenterology,
2011; 106(4):
574-88.
Rivas Manuel A, Beaudoin Mélissa, Gardet Agnes, Stevens Christine, Sharma Yashoda, Zhang Clarence K, Boucher Gabrielle, Ripke Stephan, Ellinghaus David, Burtt Noel, Fennell Tim, Kirby Andrew, Latiano Anna, Goyette Philippe, Green Todd, Halfvarson Jonas, Haritunians Talin, Korn Joshua M, Kuruvilla Finny, Lagacé Caroline, Neale Benjamin, Lo Ken Sin, Schumm Phil, Törkvist Leif, Törkvist Leif, Törkvist Leif, Törkvist Leif, Dubinsky Marla C, Brant Steven R, Silverberg Mark S, Duerr Richard H, Altshuler David, Gabriel Stacey, Lettre Guillaume, Franke Andre, D'Amato Mauro, McGovern Dermot P B, Cho Judy H, Rioux John D, Xavier Ramnik J, Daly Mark J
Deep resequencing of GWAS loci identifies independent rare variants
associated with inflammatory bowel disease
Nature genetics,
2011; 43(11):
1066-73.
Levine Arie, Griffiths Anne, Markowitz James, Wilson David C, Turner Dan, Russell Richard K, Fell John, Ruemmele Frank M, Walters Thomas, Sherlock Mary, Dubinsky Marla, Hyams Jeffrey S
Pediatric modification of the Montreal classification for inflammatory
bowel disease: the Paris classification
Inflammatory bowel diseases,
2011; 17(6):
1314-21.
Haritunians Talin, Jones Michelle R, McGovern Dermot P B, Shih David Q, Barrett Robert J, Derkowski Carrie, Dubinsky Marla C, Dutridge Debra, Fleshner Phillip R, Ippoliti Andrew, King Lily, Leshinsky-Silver Esther, Levine Arie, Melmed Gil Y, Mengesha Emebet, Vasilauskas Eric A, Ziaee Shabnam, Rotter Jerome I, Targan Stephan R, Taylor Kent D
Variants in ZNF365 isoform D are associated with Crohn's disease
Gut,
2011; 60(8):
1060-7.
McGovern Dermot P B, Jones Michelle R, Taylor Kent D, Marciante Kristin, Yan Xiaofei, Dubinsky Marla, Ippoliti Andy, Vasiliauskas Eric, Berel Dror, Derkowski Carrie, Dutridge Deb, Fleshner Phil, Shih David Q, Melmed Gil, Mengesha Emebet, King Lily, Pressman Sheila, Haritunians Talin, Guo Xiuqing, Targan Stephan R, Rotter Jerome I, Rotter Jerome I
Fucosyltransferase 2 (FUT2) non-secretor status is associated with
Crohn's disease
Human molecular genetics,
2010; 19(17):
3468-76.
Haritunians Talin, Taylor Kent D, Targan Stephan R, Dubinsky Marla, Ippoliti Andrew, Kwon Soonil, Guo Xiuqing, Melmed Gil Y, Berel Dror, Mengesha Emebet, Psaty Bruce M, Glazer Nicole L, Vasiliauskas Eric A, Rotter Jerome I, Fleshner Phillip R, McGovern Dermot P B
Genetic predictors of medically refractory ulcerative colitis
Inflammatory bowel diseases,
2010; 16(11):
1830-40.
Dubinsky Marla C, Mei Ling, Friedman Madison, Dhere Tanvi, Haritunians Talin, Hakonarson Hakon, Kim Cecilia, Glessner Joseph, Targan Stephan R, McGovern Dermot P, Taylor Kent D, Rotter Jerome I
Genome wide association (GWA) predictors of anti-TNFalpha therapeutic
responsiveness in pediatric inflammatory bowel disease
Inflammatory bowel diseases,
2010; 16(8):
1357-66.
Siegel Corey A, Siegel Lori S, Hyams Jeffrey S, Kugathasan Subra, Markowitz James, Rosh Joel R, Leleiko Neal, Mack David R, Crandall Wallace, Evans Jonathan, Keljo David J, Otley Anthony R, Oliva-Hemker Maria, Farrior Sharmayne, Langton Christine R, Wrobel Iwona T, Wahbeh Ghassan, Quiros J Antonio, Silber Gary, Bahar Ron J, Sands Bruce E, Dubinsky Marla C
Real-time tool to display the predicted disease course and treatment
response for children with Crohn's disease
Inflammatory bowel diseases,
2010; 19(17):
.
Markowitz James, Kugathasan Subra, Dubinsky Marla, Mei Ling, Crandall Wallace, LeLeiko Neal, Oliva-Hemker Maria, Rosh Joel, Evans Jonathan, Mack David, Otley Anthony, Pfefferkorn Marian, Bahar Ron, Vasiliauskas Eric, Wahbeh Ghassan, Silber Gary, Quiros J Antonio, Wrobel Iwona, Nebel Justin, Landers Carol, Picornell Yoanna, Targan Stephan, Lerer Trudy, Hyams Jeffrey
Age of diagnosis influences serologic responses in children with
Crohn's disease: a possible clue to etiology?
Inflammatory bowel diseases,
2009; 15(5):
714-9.
Wang Kai, Zhang Haitao, Kugathasan Subra, Annese Vito, Bradfield Jonathan P, Russell Richard K, Sleiman Patrick M A, Imielinski Marcin, Glessner Joseph, Hou Cuiping, Wilson David C, Walters Thomas, Kim Cecilia, Frackelton Edward C, Lionetti Paolo, Barabino Arrigo, Van Limbergen Johan, Guthery Stephen, Denson Lee, Piccoli David, Li Mingyao, Dubinsky Marla, Silverberg Mark, Griffiths Anne, Grant Struan F A, Satsangi Jack, Baldassano Robert, Hakonarson Hakon
Diverse genome-wide association studies associate the IL12/IL23
pathway with Crohn Disease
American journal of human genetics,
2009; 84(3):
399-405.
McGovern Dermot P B, Rotter Jerome I, Mei Ling, Haritunians Talin, Landers Carol, Derkowski Carrie, Dutridge Deb, Dubinsky Marla, Ippoliti Andy, Vasiliauskas Eric, Mengesha Emebet, King Lily, Pressman Sheila, Targan Stephan R, Taylor Kent D
Genetic epistasis of IL23/IL17 pathway genes in Crohn's disease
Inflammatory bowel diseases,
2009; 15(6):
883-9.
Han Xiaonan, Uchida Kanji, Jurickova Ingrid, Koch Diana, Willson Tara, Samson Charles, Bonkowski Erin, Trauernicht Anna, Kim Mi-Ok, Tomer Gitit, Dubinsky Marla, Plevy Scott, Kugathsan Subra, Trapnell Bruce C, Denson Lee A
Granulocyte-macrophage colony-stimulating factor autoantibodies in
murine ileitis and progressive ileal Crohn's disease
Gastroenterology,
2009; 136(4):
1261-71, e1-3.
McGovern Dermot P B, Taylor Kent D, Landers Carol, Derkowski Carrie, Dutridge Deb, Dubinsky Marla, Ippoliti Andy, Vasiliauskas Eric, Mei Ling, Mengesha Emebet, King Lily, Pressman Sheila, Targan Stephan R, Rotter Jerome I
MAGI2 genetic variation and inflammatory bowel disease
Inflammatory bowel diseases,
2009; 15(1):
75-83.
Colletti Richard B, Baldassano Robert N, Milov David E, Margolis Peter A, Bousvaros Athos, Crandall Wallace V, Crissinger Karen D, D'Amico Michael A, Day Andrew S, Denson Lee A, Dubinsky Marla, Ebach Dawn R, Hoffenberg Edward J, Kader Howard A, Keljo David J, Leibowitz Ian H, Mamula Petar, Pfefferkorn Marian D, Qureshi M Azim, Qureshi M Azim
Variation in care in pediatric Crohn disease
Journal of pediatric gastroenterology and nutrition,
2009; 49(3):
297-303.
Melmed Gil Y, Fleshner Phillip R, Bardakcioglu Ovunc, Ippoliti Andrew, Vasiliauskas Eric A, Papadakis Konstantinos A, Dubinsky Marla, Landers Carol, Rotter Jerome I, Targan Stephan R
Family history and serology predict Crohn's disease after ileal
pouch-anal anastomosis for ulcerative colitis
Diseases of the colon and rectum,
2008; 51(1):
100-8.
Dubinsky Marla C, Kugathasan Subra, Mei Ling, Picornell Yoana, Nebel Justin, Wrobel Iwona, Quiros Antonio, Silber Gary, Wahbeh Ghassan, Katzir Lirona, Vasiliauskas Eric, Bahar Ron, Otley Anthony, Mack David, Evans Jonathan, Rosh Joel, Hemker Maria Oliva, Leleiko Neal, Crandall Wallace, Langton Christine, Landers Carol, Taylor Kent D, Targan Stephan R, Rotter Jerome I, Markowitz James, Hyams Jeffrey, Hyams Jeffrey, Hyams Jeffrey, Hyams Jeffrey
Increased immune reactivity predicts aggressive complicating Crohn's
disease in children
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association,
2008; 6(10):
1105-11.
Fleshner Phillip, Ippoliti Andrew, Dubinsky Marla, Ognibene Steven, Vasiliauskas Eric, Chelly Marjorie, Mei Ling, Papadakis Konstantinos A, Landers Carol, Targan Stephan
A prospective multivariate analysis of clinical factors associated
with pouchitis after ileal pouch-anal anastomosis
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association,
2007; 5(8):
952-8; quiz 887.
Targan Stephan, Targan Stephan, Bousvaros Athos, Antonioli Donald A, Colletti Richard B, Dubinsky Marla C, Glickman Jonathan N, Gold Benjamin D, Griffiths Anne M, Jevon Gareth P, Higuchi Leslie M, Hyams Jeffrey S, Kirschner Barbara S, Kugathasan Subra, Baldassano Robert N, Russo Pierre A
Differentiating ulcerative colitis from Crohn disease in children and
young adults: report of a working group of the North American Society
for Pediatric Gastroenterology, Hepatology, and Nutrition and the
Crohn's and Colitis Foundation of America
Journal of pediatric gastroenterology and nutrition,
2007; 44(5):
653-74.
Dubinsky Marla C, Wang Dai, Picornell Yoana, Wrobel Iwona, Katzir Lirona, Quiros Antonio, Dutridge Debra, Wahbeh Ghassan, Silber Gary, Bahar Ron, Mengesha Emebet, Targan Stephan R, Taylor Kent D, Rotter Jerome I, Rotter Jerome I
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's
disease
Inflammatory bowel diseases,
2007; 13(5):
511-5.
Bousvaros Athos, Sylvester Francisco, Kugathasan Subra, Szigethy Eva, Fiocchi Claudio, Colletti Richard, Otley Anthony, Amre Devendra, Ferry George, Czinn Steven J, Splawski Judy B, Oliva-Hemker Maria, Hyams Jeffrey S, Faubion William A, Kirschner Barbara S, Dubinsky Marla C, Dubinsky Marla C
Challenges in pediatric inflammatory bowel disease
Inflammatory bowel diseases,
2006; 12(9):
885-913.
Dubinsky Marla C, Lin Ying-Chao, Dutridge Debra, Picornell Yoana, Landers Carol J, Farrior Sharmayne, Wrobel Iwona, Quiros Antonio, Vasiliauskas Eric A, Grill Bruce, Israel David, Bahar Ron, Christie Dennis, Wahbeh Ghassan, Silber Gary, Dallazadeh Saied, Shah Praful, Thomas Danny, Kelts Drew, Hershberg Robert M, Elson Charles O, Targan Stephan R, Taylor Kent D, Rotter Jerome I, Yang Huiying, Yang Huiying
Serum immune responses predict rapid disease progression among
children with Crohn's disease: immune responses predict disease
progression
The American journal of gastroenterology,
2006; 101(2):
360-7.
Papadakis Konstantinos A, Shaye Omid A, Vasiliauskas Eric A, Ippoliti Andrew, Dubinsky Marla C, Birt Jaime, Paavola Jane, Lee Susie K, Price Joanne, Targan Stephan R, Abreu Maria T
Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients
with an attenuated response to infliximab
The American journal of gastroenterology,
2005; 100(1):
75-9.
Hui Thomas, Landers Carol, Vasiliauskas Eric, Abreu Maria, Dubinsky Marla, Papadakis Konstantinos A, Price Joanne, Lin Ying-Chao, Huiying Yang, Targan Stephan, Fleshner Phillip
Serologic responses in indeterminate colitis patients before ileal
pouch-anal anastomosis may determine those at risk for continuous
pouch inflammation
Diseases of the colon and rectum,
2005; 48(6):
1254-62.
Kugathasan Subra, Dubinsky Marla C, Keljo David, Moyer M Susan, Rufo Paul A, Wyllie Robert, Zachos Mary, Hyams Jeffrey
Severe colitis in children
Journal of pediatric gastroenterology and nutrition,
2005; 41(4):
375-85.
Youdim Adrienne, Vasiliauskas Eric A, Targan Stephan R, Papadakis Konstantinos A, Ippoliti Andrew, Dubinsky Marla C, Lechago Juan, Paavola Jane, Loane Jaime, Lee Susie K, Gaiennie Joanne, Smith Katie, Do Jason, Abreu Maria T
A pilot study of adalimumab in infliximab-allergic patients
Inflammatory bowel diseases,
2004; 10(4):
333-8.
Geller Stephen A, Dubinsky Marla C, Poordad F Fred, Vasiliauskas Eric A, Cohen Arthur H, Abreu Maria T, Tran Tram, Martin Paul, Vierling John M, Targan Stephan R
Early hepatic nodular hyperplasia and submicroscopic fibrosis
associated with 6-thioguanine therapy in inflammatory bowel disease
The American journal of surgical pathology,
2004; 28(9):
1204-11.
Dubinsky Marla C, Vasiliauskas Eric A, Singh Hardeep, Abreu Maria T, Papadakis Kostas A, Tran Tram, Martin Paul, Vierling John M, Geller Stephen A, Targan Stephan R, Poordad Fred F
6-thioguanine can cause serious liver injury in inflammatory bowel
disease patients
Gastroenterology,
2003; 125(2):
298-303.