Brad Spellberg, M.D.


Work Titles and Affiliation
UCLA Associate Professor, Medicine
Education:
Degrees:
M.D.

Contact Information:

Work Email Address:

bspellberg@labiomed.org


Work Phone Number:

(310) 222-5381

(310) 781-3680

(310) 782-2016

Mailing Address:

1124 West Carson Street
Torrance, CA 90502

Publications:

Lin Lin, Tan Brandon, Pantapalangkoor Paul, Ho Tiffany, Hujer Andrea M, Taracila Magdalena A, Bonomo Robert A, Spellberg Brad   Acinetobacter baumannii rOmpA vaccine dose alters immune polarization and immunodominant epitopes Vaccine, 2013; 31(2): 313-8.
Spellberg Brad, Sue Darryl, Chang Dong, Witt Mallory   Change in intern calls at night after a work hour restriction process change JAMA internal medicine, 2013; 173(8): 707-9.
Spellberg Brad   End points in trials of treatments for skin infections JAMA : the journal of the American Medical Association, 2013; 309(20): 2091-2.
Thompson George, Wang Sharon, Bercovitch Robert, Bolaris Michael, Van Den Akker Dane, Taylor Sandra, Lopez Rodrigo, Catanzaro Antonio, Cadena Jose, Chin-Hong Peter, Spellberg Brad   Routine CSF Analysis in Coccidioidomycosis Is Not Required PloS one, 2013; 8(5): e64249.
Bartlett John G, Gilbert David N, Spellberg Brad   Seven ways to preserve the miracle of antibiotics Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013; 56(10): 1445-50.
Russo Thomas A, Beanan Janet M, Olson Ruth, MacDonald Ulrike, Cox Andrew D, St Michael Frank, Vinogradov Evgeny V, Spellberg Brad, Luke-Marshall Nicole R, Campagnari Anthony A   The K1 capsular polysaccharide from Acinetobacter baumannii is a potential therapeutic target via passive immunization Infection and immunity, 2013; 81(3): 915-22.
Spellberg Brad, Bartlett John G, Gilbert David N   The future of antibiotics and resistance The New England journal of medicine, 2013; 368(4): 299-302.
Spellberg Brad, Lewis Roger J, Sue Darryl, Chavoshan Bahman, Vintch Janine, Munekata Mark, Kim Caroline, Lanks Charles, Witt Mallory D, Stringer William, Harrington Darrell   A controlled investigation of optimal internal medicine ward team structure at a teaching hospital PloS one, 2012; 7(4): e35576.
Luo Guanpingshen, Lin Lin, Ibrahim Ashraf S, Baquir Beverlie, Pantapalangkoor Paul, Bonomo Robert A, Doi Yohei, Adams Mark D, Russo Thomas A, Spellberg Brad   Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infection PloS one, 2012; 7(1): e29446.
Spellberg Brad, Ibrahim Ashraf, Roilides Emmanuel, Lewis Russel E, Lortholary Olivier, Petrikkos George, Kontoyiannis Dimitrios P, Walsh Thomas J   Combination therapy for mucormycosis: why, what, and how? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012; 54 Suppl 1(4): S73-8.
Spellberg Brad, Daum Robert   Development of a vaccine against Staphylococcus aureus Seminars in immunopathology, 2012; 34(2): 335-48.
Luo Guanpingsheng, Spellberg Brad, Gebremariam Teclegiorgis, Bolaris Michael, Lee Hongkyu, Fu Yue, French Samuel W, Ibrahim Ashraf S   Diabetic murine models for Acinetobacter baumannii infection The Journal of antimicrobial chemotherapy, 2012; 67(6): 1439-45.
Kontoyiannis Dimitrios P, Lewis Russell E, Lortholary Oliver, Lotholary Oliver, Spellberg Brad, Petrikkos Georgios, Roillides Emmanuel, Ibrahim Ashraf, Walsh Thomas J   Future directions in mucormycosis research Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012; 54 Suppl 1(4): S79-85.
Spellberg Brad   Gastrointestinal mucormycosis: an evolving disease Gastroenterology & hepatology, 2012; 8(2): 140-2.
Lewis Russell E, Lortholary Olivier, Spellberg Brad, Roilides Emmanuel, Kontoyiannis Dimitrios P, Walsh Thomas J   How does antifungal pharmacology differ for mucormycosis versus aspergillosis? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012; 54 Suppl 1(4): S67-72.
Lin Lin, Tan Brandon, Pantapalangkoor Paul, Ho Tiffany, Baquir Beverlie, Tomaras Andrew, Montgomery Justin I, Reilly Usa, Barbacci Elsa G, Hujer Kristine, Bonomo Robert A, Fernandez Lucia, Hancock Robert E W, Adams Mark D, French Samuel W, Buslon Virgil S, Spellberg Brad   Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis mBio, 2012; 3(5): .
Lin Lin, Ibrahim Ashraf S, Baquir Beverlie, Palosaari Andrew, Spellberg Brad   Luminescent-activated transfected killer cells to monitor leukocyte trafficking during systemic bacterial and fungal infection The Journal of infectious diseases, 2012; 205(2): 337-47.
Baquir Beverlie, Lemaire Sandrine, Van Bambeke Françoise, Tulkens Paul M, Lin Lin, Spellberg Brad   Macrophage killing of bacterial and fungal pathogens is not inhibited by intense intracellular accumulation of the lipoglycopeptide antibiotic oritavancin Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012; 54 Suppl 3(6): S229-32.
Shlaes David M, Spellberg Brad   Overcoming the challenges to developing new antibiotics Current opinion in pharmacology, 2012; 12(5): 522-6.
Ibrahim Ashraf S, Spellberg Brad, Walsh Thomas J, Kontoyiannis Dimitrios P   Pathogenesis of mucormycosis Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012; 54 Suppl 1(4): S16-22.
Daum Robert S, Spellberg Brad   Progress toward a Staphylococcus aureus vaccine Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012; 54(4): 560-7.
Spellberg Brad, Kontoyiannis Dimitrios P, Fredricks David, Morris Michele I, Perfect John R, Chin-Hong Peter V, Ibrahim Ashraf S, Brass Eric P   Risk factors for mortality in patients with mucormycosis Medical mycology : official publication of the International Society for Human and Animal Mycology, 2012; 54 Suppl 3(6): .
Spellberg Brad, Lipsky Benjamin A   Systemic antibiotic therapy for chronic osteomyelitis in adults Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2012; 54(3): 393-407.
Spellberg Brad, Ibrahim Ashraf S, Chin-Hong Peter V, Kontoyiannis Dimitrios P, Morris Michele I, Perfect John R, Fredricks David, Brass Eric P   The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) study: a randomized, double-blinded, placebo-controlled trial The Journal of antimicrobial chemotherapy, 2012; 67(3): 715-22.
Spellberg Brad, Sharma Priya, Rex John H   The critical impact of time discounting on economic incentives to overcome the antibiotic market failure Nature reviews. Drug discovery, 2012; 11(2): 168.
Spellberg Brad   Acute bacterial skin and skin structure infection trials: the bad is the enemy of the good Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011; 53(12): 1308-9; author reply 1309-10.
Spellberg Brad, Spellberg Brad, Blaser Martin, Guidos Robert J, Boucher Helen W, Bradley John S, Eisenstein Barry I, Gerding Dale, Lynfield Ruth, Reller L Barth, Rex John, Schwartz David, Septimus Edward, Tenover Fred C, Gilbert David N   Combating antimicrobial resistance: policy recommendations to save lives Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2011; 52 Suppl 5(12): S397-428.
Ibrahim Ashraf S, Gebremariam Teclegiorgis, Luo Guanpingsheng, Fu Yue, French Samuel W, Edwards John E, Spellberg Brad   Combination therapy of murine mucormycosis or aspergillosis with iron chelation, polyenes, and echinocandins Antimicrobial agents and chemotherapy, 2011; 55(4): 1768-70.
Spellberg Brad, Lewis Roger J, Boucher Helen W, Brass Eric P   Design of clinical trials of antibacterial agents for community-acquired bacterial pneumonia Clinical investigation, 2011; 1(1): 19-32.
Miller Loren G, McKinnell James A, Vollmer Michael E, Spellberg Brad   Impact of methicillin-resistant Staphylococcus aureus prevalence among S. aureus isolates on surgical site infection risk after coronary artery bypass surgery Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America, 2011; 32(4): 342-50.
Adams-Haduch Jennifer M, Onuoha Ezenwa O, Bogdanovich Tatiana, Tian Guo-Bao, Marschall Jonas, Urban Carl M, Spellberg Brad J, Rhee Diane, Halstead Diane C, Pasculle Anthony W, Doi Yohei   Molecular epidemiology of carbapenem-nonsusceptible Acinetobacter baumannii in the United States Journal of clinical microbiology, 2011; 49(11): 3849-54.
Spellberg Brad   The antibiotic crisis: can we reverse 65 years of failed stewardship? Archives of internal medicine, 2011; 171(12): 1080-1.
Spellberg Brad, Boucher Helen, Bradley John, Das Anita, Talbot George   To treat or not to treat: adjunctive antibiotics for uncomplicated abscesses Annals of emergency medicine, 2011; 57(2): 183-5.
Spellberg Brad   Vaccines for invasive fungal infections F1000 medicine reports, 2011; 3(1): 13.
Spellberg Brad, Daum Robert   A new view on development of a Staphylococcus aureus vaccine: insights from mice and men Human vaccines, 2010; 6(10): 857-9.
Luo Guanpingsheng, Ibrahim Ashraf S, Spellberg Brad, Nobile Clarissa J, Mitchell Aaron P, Fu Yue   Candida albicans Hyr1p confers resistance to neutrophil killing and is a potential vaccine target The Journal of infectious diseases, 2010; 201(11): 1718-28.
Spellberg Brad   Geographic differences in Medicare spending The New England journal of medicine, 2010; 363(17): 1678; author reply 1678-9.
Baquir Beverlie, Lin Lin, Ibrahim Ashraf S, Fu Yue, Avanesian Valentina, Tu Ang, Edwards John, Spellberg Brad   Immunological reactivity of blood from healthy humans to the rAls3p-N vaccine protein The Journal of infectious diseases, 2010; 201(3): 473-7.
Quan Clifford, Spellberg Brad   Mucormycosis, pseudallescheriasis, and other uncommon mold infections Proceedings of the American Thoracic Society, 2010; 7(3): 210-5.
Spellberg Brad, Ibrahim Ashraf S   Recent advances in the treatment of mucormycosis Current infectious disease reports, 2010; 12(6): 423-9.
Daum Robert, Daum Robert, Daum Robert, Daum Robert, Spellberg Brad, Talbot George   Recommended design features of future clinical trials of antibacterial agents for hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010; 51 Suppl 1(10): S150-70.
Lin Lin, Ibrahim Ashraf S, Baquir Beverlie, Fu Yue, Applebaum David, Schwartz Julie, Wang Amy, Avanesian Valentina, Spellberg Brad   Safety and efficacy of activated transfected killer cells for neutropenic fungal infections The Journal of infectious diseases, 2010; 201(11): 1708-17.
Spellberg Brad   Skin and soft-tissue infections: modern evolution of an ancient problem Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010; 51(8): 904-6.
Liu Mingfu, Spellberg Brad, Phan Quynh T, Fu Yue, Fu Yong, Lee Amy S, Edwards John E, Filler Scott G, Ibrahim Ashraf S   The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice The Journal of clinical investigation, 2010; 120(6): 1914-24.
Ibrahim Ashraf S, Gebremariam Teclegiorgis, Lin Lin, Luo Guanpingsheng, Husseiny Mohamed I, Skory Christopher D, Fu Yue, French Samuel W, Edwards John E, Spellberg Brad   The high affinity iron permease is a key virulence factor required for Rhizopus oryzae pathogenesis Molecular microbiology, 2010; 77(3): 587-604.
Ibrahim Ashraf S, Gebremariam Teclegiorgis, French Samuel W, Edwards John E, Spellberg Brad   The iron chelator deferasirox enhances liposomal amphotericin B efficacy in treating murine invasive pulmonary aspergillosis The Journal of antimicrobial chemotherapy, 2010; 65(2): 289-92.
Spellberg Brad, Talbot George H, Boucher Helen W, Bradley John S, Gilbert David, Scheld W Michael, Edwards John, Bartlett John G, Bartlett John G   Antimicrobial agents for complicated skin and skin-structure infections: justification of noninferiority margins in the absence of placebo-controlled trials Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009; 49(3): 383-91.
Boucher Helen W, Talbot George H, Bradley John S, Edwards John E, Gilbert David, Rice Louis B, Scheld Michael, Spellberg Brad, Bartlett John   Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009; 48(1): 1-12.
Ibrahim Ashraf S, Edwards John E, Bryant Richard, Spellberg Brad   Economic burden of mucormycosis in the United States: can a vaccine be cost-effective? Medical mycology : official publication of the International Society for Human and Animal Mycology, 2009; 47(6): 592-600.
Lin Lin, Ibrahim Ashraf S, Baquir Beverlie, Avanesian Valentina, Fu Yue, Spellberg Brad   Immunological surrogate marker of rAls3p-N vaccine-induced protection against Staphylococcus aureus FEMS immunology and medical microbiology, 2009; 55(3): 293-5.
Ibrahim Ashraf S, Gebremariam Teclegiorgis, Schwartz Julie A, Edwards John E, Spellberg Brad   Posaconazole mono- or combination therapy for treatment of murine zygomycosis Antimicrobial agents and chemotherapy, 2009; 53(2): 772-5.
Spellberg Brad, Walsh Thomas J, Kontoyiannis Dimitrios P, Edwards John, Ibrahim Ashraf S   Recent advances in the management of mucormycosis: from bench to bedside Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2009; 48(12): 1743-51.
Spellberg Brad, Andes David, Perez Mario, Anglim Anne, Bonilla Hector, Mathisen Glenn E, Walsh Thomas J, Ibrahim Ashraf S   Safety and outcomes of open-label deferasirox iron chelation therapy for mucormycosis Antimicrobial agents and chemotherapy, 2009; 53(7): 3122-5.
Lin Lin, Ibrahim Ashraf S, Xu Xin, Farber Joshua M, Avanesian Valentina, Baquir Beverlie, Fu Yue, French Samuel W, Edwards John E, Spellberg Brad   Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice PLoS pathogens, 2009; 5(12): e1000703.
Freifeld Alison, Proia Laurie, Andes David, Baddour Larry M, Blair Janis, Spellberg Brad, Arnold Sandra, Lentnek Arnold, Wheat L Joseph   Voriconazole use for endemic fungal infections Antimicrobial agents and chemotherapy, 2009; 53(4): 1648-51.
Spellberg Brad   Antibiotic resistance and antibiotic development The Lancet infectious diseases, 2008; 8(4): 211-2; author reply 212-4.
Spellberg Brad, Ibrahim Ashraf S, Lin Lin, Avanesian Valentina, Fu Yue, Lipke Peter, Otoo Henry, Ho Tiffany, Edwards John E   Antibody titer threshold predicts anti-candidal vaccine efficacy even though the mechanism of protection is induction of cell-mediated immunity The Journal of infectious diseases, 2008; 197(7): 967-71.
Ibrahim Ashraf S, Gebremariam Teclegiorgis, Liu Mingfu, Chamilos Georgios, Kontoyiannis Dimitrios, Mink Richard, Kwon-Chung Kyung J, Fu Yue, Skory Christopher D, Edwards John E, Spellberg Brad   Bacterial endosymbiosis is widely present among zygomycetes but does not contribute to the pathogenesis of mucormycosis The Journal of infectious diseases, 2008; 198(7): 1083-90.
Ibrahim Ashraf S, Gebremariam Teclegiorgis, Fu Yue, Edwards John E, Spellberg Brad   Combination echinocandin-polyene treatment of murine mucormycosis Antimicrobial agents and chemotherapy, 2008; 52(4): 1556-8.
Reed Caitlin, Bryant Richard, Ibrahim Ashraf S, Edwards John, Filler Scott G, Goldberg Robert, Spellberg Brad   Combination polyene-caspofungin treatment of rhino-orbital-cerebral mucormycosis Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008; 47(3): 364-71.
Ibrahim Ashraf S, Gebremariam Teclegiorgis, Husseiny Mohamed I, Stevens David A, Fu Yue, Edwards John E, Spellberg Brad   Comparison of lipid amphotericin B preparations in treating murine zygomycosis Antimicrobial agents and chemotherapy, 2008; 52(4): 1573-6.
Lin Lin, Ibrahim Ashraf S, Avanesian Valentina, Edwards John E, Fu Yue, Baquir Beverlie, Taub Rebecca, Spellberg Brad   Considerable differences in vaccine immunogenicities and efficacies related to the diluent used for aluminum hydroxide adjuvant Clinical and vaccine immunology : CVI, 2008; 15(3): 582-4.
Spellberg Brad   Dr. William H. Stewart: mistaken or maligned? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008; 47(2): 294.
Spellberg Brad, Fleming Thomas R, Gilbert David N   Executive summary: workshop on issues in the design and conduct of clinical trials of antibacterial drugs in the treatment of community-acquired pneumonia Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008; 47 Suppl 3(6): S105-7.
Fu Yue, Luo Guanpingsheng, Spellberg Brad J, Edwards John E, Ibrahim Ashraf S   Gene overexpression/suppression analysis of candidate virulence factors of Candida albicans Eukaryotic cell, 2008; 7(3): 483-92.
Ibrahim Ashraf S, Spellberg Brad, Edwards John   Iron acquisition: a novel perspective on mucormycosis pathogenesis and treatment Current opinion in infectious diseases, 2008; 21(6): 620-5.
Spellberg Brad, Talbot George H, Brass Eric P, Bradley John S, Boucher Helen W, Gilbert David N, Gilbert David N   Position paper: recommended design features of future clinical trials of antibacterial agents for community-acquired pneumonia Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008; 47 Suppl 3(6): S249-65.
Spellberg Brad, Ibrahim Ashraf S, Yeaman Michael R, Lin Lin, Fu Yue, Avanesian Valentina, Bayer Arnold S, Filler Scott G, Lipke Peter, Otoo Henry, Edwards John E   The antifungal vaccine derived from the recombinant N terminus of Als3p protects mice against the bacterium Staphylococcus aureus Infection and immunity, 2008; 76(10): 4574-80.
Spellberg Brad, Guidos Robert, Gilbert David, Bradley John, Boucher Helen W, Scheld W Michael, Bartlett John G, Edwards John, Edwards John   The epidemic of antibiotic-resistant infections: a call to action for the medical community from the Infectious Diseases Society of America Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008; 46(2): 155-64.
Miller Loren G, Perdreau-Remington Franciose, Bayer Arnold S, Diep Binh, Tan Nelly, Bharadwa Kiran, Tsui Jennifer, Perlroth Joshua, Shay Anthony, Tagudar Grace, Ibebuogu Uzoma, Spellberg Brad   Clinical and epidemiologic characteristics cannot distinguish community-associated methicillin-resistant Staphylococcus aureus infection from methicillin-susceptible S. aureus infection: a prospective investigation Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007; 44(4): 471-82.
Perlroth Joshua, Choi Bryan, Spellberg Brad   Nosocomial fungal infections: epidemiology, diagnosis, and treatment Medical mycology : official publication of the International Society for Human and Animal Mycology, 2007; 45(4): 321-46.
Spellberg Brad J, Collins Mary, Avanesian Valentina, Gomez Mayela, Edwards John E, Cogle Christopher, Applebaum David, Fu Yue, Ibrahim Ashraf S   Optimization of a myeloid cell transfusion strategy for infected neutropenic hosts Journal of leukocyte biology, 2007; 81(3): 632-41.
Spellberg Brad   Prospects for and barriers to a fungal vaccine Expert opinion on biological therapy, 2007; 7(12): 1785-8.
Ibrahim Ashraf S, Gebermariam Teclegiorgis, Fu Yue, Lin Lin, Husseiny Mohamed I, French Samuel W, Schwartz Julie, Skory Christopher D, Edwards John E, Spellberg Brad J   The iron chelator deferasirox protects mice from mucormycosis through iron starvation The Journal of clinical investigation, 2007; 117(9): 2649-57.
Rieg Gunter, Spellberg Brad, Schwartz Julie, Fu Yue, Edwards John E, Sheppard Donald C, Ibrahim Ashraf S   Antifungal prophylaxis is effective against murine invasive pulmonary aspergillosis Antimicrobial agents and chemotherapy, 2006; 50(8): 2895-6.
Spellberg Brad, Schwartz Julie, Fu Yue, Avanesian Valentina, Adler-Moore Jill, Edwards John E, Ibrahim Ashraf S   Comparison of antifungal treatments for murine fusariosis The Journal of antimicrobial chemotherapy, 2006; 58(5): 973-9.
Spellberg Brad J, Filler Scott G, Edwards John E   Current treatment strategies for disseminated candidiasis Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006; 42(2): 244-51.
Reed Caitlin, Ibrahim Ashraf, Edwards John E, Walot Irwin, Spellberg Brad   Deferasirox, an iron-chelating agent, as salvage therapy for rhinocerebral mucormycosis Antimicrobial agents and chemotherapy, 2006; 50(11): 3968-9.
Ibrahim Ashraf S, Edwards John E, Fu Yue, Spellberg Brad   Deferiprone iron chelation as a novel therapy for experimental mucormycosis The Journal of antimicrobial chemotherapy, 2006; 58(5): 1070-3.
Spellberg Brad J, Ibrahim Ashraf S, Avanesian Valentina, Fu Yue, Myers Carter, Phan Quynh T, Filler Scott G, Yeaman Michael R, Edwards John E   Efficacy of the anti-Candida rAls3p-N or rAls1p-N vaccines against disseminated and mucosal candidiasis The Journal of infectious diseases, 2006; 194(2): 256-60.
Spellberg Brad   Immunoglobulin G2 antibodies and HIV-infected long-term nonprogressors: what is the mechanism? The Journal of infectious diseases, 2006; 193(7): 1047; author reply 1047-8.
Ibrahim Ashraf S, Spellberg Brad J, Avanesian Valentina, Fu Yue, Edwards John E   The anti-Candida vaccine based on the recombinant N-terminal domain of Als1p is broadly active against disseminated candidiasis Infection and immunity, 2006; 74(5): 3039-41.
Spellberg Brad J, Collins Mary, French Samuel W, Edwards John E, Fu Yue, Ibrahim Ashraf S   A phagocytic cell line markedly improves survival of infected neutropenic mice Journal of leukocyte biology, 2005; 78(2): 338-44.
Spellberg Brad   Carl von Clausewitz (1780-1831) and cholera: the cause of World War II? Journal of medical biography, 2005; 13(2): 108-12.
Ibrahim Ashraf S, Bowman Joel C, Avanessian Valentina, Brown Keturah, Spellberg Brad, Edwards John E, Douglas Cameron M   Caspofungin inhibits Rhizopus oryzae 1,3-beta-D-glucan synthase, lowers burden in brain measured by quantitative PCR, and improves survival at a low but not a high dose during murine disseminated zygomycosis Antimicrobial agents and chemotherapy, 2005; 49(2): 721-7.
Spellberg Brad, Fu Yue, Edwards John E, Ibrahim Ashraf S   Combination therapy with amphotericin B lipid complex and caspofungin acetate of disseminated zygomycosis in diabetic ketoacidotic mice Antimicrobial agents and chemotherapy, 2005; 49(2): 830-2.
Spellberg Brad   Is computed tomography of the head useful before lumbar puncture? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005; 40(7): 1061; author reply 1062-3.
Spellberg Brad, Ibrahim Ashraf S, Edwards John E, Filler Scott G   Mice with disseminated candidiasis die of progressive sepsis The Journal of infectious diseases, 2005; 192(2): 336-43.
Miller Loren G, Perdreau-Remington Francoise, Rieg Gunter, Mehdi Sheherbano, Perlroth Josh, Bayer Arnold S, Tang Angela W, Phung Tieu O, Spellberg Brad   Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles The New England journal of medicine, 2005; 352(14): 1445-53.
Spellberg Brad, Edwards John, Ibrahim Ashraf   Novel perspectives on mucormycosis: pathophysiology, presentation, and management Clinical microbiology reviews, 2005; 18(3): 556-69.
Ibrahim Ashraf S, Spellberg Brad, Avanessian Valentina, Fu Yue, Edwards John E   Rhizopus oryzae adheres to, is phagocytosed by, and damages endothelial cells in vitro Infection and immunity, 2005; 73(2): 778-83.
Spellberg Brad J, Ibrahim Ashraf S, Avenissian Valentina, Filler Scott G, Myers Carter L, Fu Yue, Edwards John E   The anti-Candida albicans vaccine composed of the recombinant N terminus of Als1p reduces fungal burden and improves survival in both immunocompetent and immunocompromised mice Infection and immunity, 2005; 73(9): 6191-3.
Ibrahim Ashraf S, Spellberg Brad J, Avenissian Valentina, Fu Yue, Filler Scott G, Edwards John E   Vaccination with recombinant N-terminal domain of Als1p improves survival during murine disseminated candidiasis by enhancing cell-mediated, not humoral, immunity Infection and immunity, 2005; 73(2): 999-1005.
Spellberg Brad, Witt Mallory D, Beck C Keith   Amphotericin B: is a lipid-formulation gold standard feasible? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004; 38(2): 304-5; author reply 306-7.
Fu Yue, Lee Helen, Collins Mary, Tsai Huei-Fung, Spellberg Brad, Edwards John E, Kwon-Chung Kyung J, Ibrahim Ashraf S   Cloning and functional characterization of the Rhizopus oryzae high affinity iron permease (rFTR1) gene FEMS microbiology letters, 2004; 235(1): 169-76.
Spellberg Brad, Yoo Thomas, Bayer Arnold S   Reversal of linezolid-associated cytopenias, but not peripheral neuropathy, by administration of vitamin B6 The Journal of antimicrobial chemotherapy, 2004; 54(4): 832-5.
Miller Loren G, Spellberg Brad   Spider bites and infections caused by community-associated methicillin-resistant Staphylococcus aureus Surgical infections, 2004; 5(3): 321-2; author reply 322.
Miller Loren G, Spellberg Brad   Treatment of community-associated methicillin-resistant Staphylococcus aureus skin and soft tissue infections with drainage but no antibiotic therapy The Pediatric infectious disease journal, 2004; 23(8): 795; author reply 795-6.
Spellberg Brad, Powers John H, Brass Eric P, Miller Loren G, Edwards John E   Trends in antimicrobial drug development: implications for the future Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004; 38(9): 1279-86.

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Information from U.S. National Library of Medicine.

Abscess Acinetobacter Acinetobacter Infections Acinetobacter baumannii Acyclovir Adoptive Transfer Adult Affect Aged Agglutination Amphotericin B Animals Anti-Bacterial Agents Anti-Infective Agents Antibodies Antibodies, Fungal Antifungal Agents Antigen-Antibody Complex Antigens Antigens, Bacterial Apoptosis Aspergillosis Aspergillus Aspergillus fumigatus B-Lymphocytes Bacteremia Bacteria Bacterial Infections Bacterial Vaccines Benzoates Biological Assay Biological Markers Biomedical Research Blood Blood Circulation Body Temperature Candida Candida albicans Candidiasis Carbapenems Carbohydrates Cause of Death Cell Line Cell Survival Cells Chemotactic Factors Clinical Trials as Topic Clone Cells Colistin Combined Modality Therapy Communicable Diseases Community-Acquired Infections Competitive Bidding Consensus Cross Infection Cyclic AMP Cytokines Dendritic Cells Diagnosis Disease Disease Models, Animal Double-Blind Method Drug Discovery Drug Resistance Drug Resistance, Bacterial Drug Resistance, Microbial Drug Resistance, Multiple, Bacterial Drug Resistance, Multiple, Fungal Drug Therapy, Combination Drugs, Investigational Echinocandins Economics Elements Engineering Enzyme-Linked Immunosorbent Assay Enzymes Epitope Mapping Epitopes Flow Cytometry Foundations Fungal Proteins Fungal Vaccines Ganciclovir Genes Genome, Fungal Genomics Goals Gram-Negative Bacteria Growth Guidelines as Topic HL-60 Cells Head Health Health Policy Heating Hospitalization Hospitals Humans Immune Sera Immune System Immunity Immunization Immunization, Passive Immunocompromised Host Immunoglobulin A Immunoglobulin Class Switching Immunoglobulin G Immunotherapy Incidence Industry Infection Inflammation Integration Host Factors Interleukin-17 Interleukin-4 Iron Iron Chelating Agents Kidney Killer Cells, Natural Kinetics Knowledge Laboratories Lead Leukocyte Transfusion Leukocytes Libraries Life Lipid A Lipids Lipopolysaccharides Longevity Luminescence Lung Lymphocyte Activation Marketing Membrane Proteins Metabolomics Methicillin Methicillin Resistance Methods Mice Mice, Inbred BALB C Mice, Knockout Microbial Viability Middle Aged Monobactams Mortality Mucorales Mucormycosis Mutation Mycoses Neutropenia Neutrophil Infiltration Organophosphates Patients Peripheral Nervous System Diseases Periplasm Phagocytes Phagocytosis Pharmaceutical Preparations Phenotype Physicians Placebos Plasmids Pneumonia Pneumonia, Bacterial Polyenes Polysaccharides Population Proteins Public Health Pyrimidines Recombinant Proteins Research Research Design Research Personnel Reverse Transcriptase Polymerase Chain Reaction Rhizopus Risk Risk Factors Role Safety Sepsis Serial Passage Serotyping Serum Siderophores Skin Skin Diseases, Bacterial Soft Tissue Infections Spleen Staphylococcal Infections Staphylococcal Vaccines Staphylococcus aureus Strikes, Employee Suicide Superoxides Survival Analysis Syndrome Tail Technology Thymidine Kinase Time Time Factors Tissue Survival Tissues Toxicology Transfection Translations Treatment Outcome Triazoles United States Food and Drug Administration Universities Vaccination Vaccines Veins Virulence Virulence Factors Work Wound Infection beta-Lactam Resistance

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