Publications:
A selected list of publications:
Parks Brian W, Nam Elizabeth, Org Elin, Kostem Emrah, Norheim Frode, Hui Simon T, Pan Calvin, Civelek Mete, Rau Christoph D, Bennett Brian J, Mehrabian Margarete, Ursell Luke K, He Aiqing, Castellani Lawrence W, Zinker Bradley, Kirby Mark, Drake Thomas A, Drevon Christian A, Knight Rob, Gargalovic Peter, Kirchgessner Todd, Eskin Eleazar, Lusis Aldons J
Genetic control of obesity and gut microbiota composition in response
to high-fat, high-sucrose diet in mice
Cell metabolism,
2013; 17(1):
141-52.
Kim Juyong Brian, Deluna Andres, Mungrue Imran N, Vu Christine, Pouldar Delila, Civelek Mete, Orozco Luz, Wu Judy, Wang Xuping, Charugundla Sarada, Castellani Lawrence W, Rusek Marta, Jakubowski Hieronim, Jakobowski Hieronim, Lusis Aldons J
Effect of 9p21.3 coronary artery disease locus neighboring genes on
atherosclerosis in mice
Circulation,
2012; 126(15):
1896-906.
Martin Lisa J, Lau Edward, Singh Harpreet, Vergnes Laurent, Tarling Elizabeth J, Mehrabian Margarete, Mungrue Imran, Xiao Sheila, Shih Diana, Castellani Lawrence, Ping Peipei, Reue Karen, Stefani Enrico, Drake Thomas A, Bostrom Kristina, Lusis Aldons J
ABCC6 localizes to the mitochondria-associated membrane
Circulation research,
2012; 111(5):
516-20.
Hong Cynthia, Bradley Michele N, Rong Xin, Wang Xuping, Wagner Alan, Grijalva Victor, Castellani Lawrence W, Salazar Jon, Realegeno Susan, Boyadjian Rima, Fogelman Alan M, Van Lenten Brian J, Reddy Srinivasa T, Lusis Aldons J, Tangirala Rajendra K, Tontonoz Peter
LXRα is uniquely required for maximal reverse cholesterol transport
and atheroprotection in ApoE-deficient mice
Journal of lipid research,
2012; 53(6):
1126-33.
Davis Richard C, van Nas Atila, Castellani Lawrence W, Zhao Yi, Zhou Zhiqiang, Wen Pingzi, Yu Suzanne, Qi Hongxiu, Rosales Melenie, Schadt Eric E, Broman Karl W, Péterfy Miklós, Lusis Aldons J
Systems genetics of susceptibility to obesity-induced diabetes in
mice
Physiological genomics,
2012; 44(1):
1-13.
Barajas Berenice, Che Nam, Yin Fen, Rowshanrad Amir, Orozco Luz D, Gong Ke Wei, Wang Xuping, Castellani Lawrence W, Reue Karen, Lusis Aldons J, Araujo Jesus A
NF-E2-related factor 2 promotes atherosclerosis by effects on plasma
lipoproteins and cholesterol transport that overshadow antioxidant
protection
Arteriosclerosis, thrombosis, and vascular biology,
2011; 31(1):
58-66.
Davis Richard C, Castellani Lawrence W, Hosseini Maryam, Ben-Zeev Osnat, Mao Hui Z, Weinstein Michael M, Jung Dae Young, Jun John Y, Kim Jason K, Lusis Aldons J, Péterfy Miklós
Early hepatic insulin resistance precedes the onset of diabetes in
obese C57BLKS-db/db mice
Diabetes,
2010; 59(7):
1616-25.
Bennett Brian J, Farber Charles R, Orozco Luz, Kang Hyun Min, Ghazalpour Anatole, Siemers Nathan, Neubauer Michael, Neuhaus Isaac, Yordanova Roumyana, Guan Bo, Truong Amy, Yang Wen-pin, He Aiqing, Kayne Paul, Gargalovic Peter, Kirchgessner Todd, Pan Calvin, Castellani Lawrence W, Kostem Emrah, Furlotte Nicholas, Drake Thomas A, Eskin Eleazar, Lusis Aldons J
A high-resolution association mapping panel for the dissection of
complex traits in mice
Genome research,
2010; 20(2):
281-90.
Gargalovic Peter S, Erbilgin Ayça, Kohannim Omid, Pagnon Joanne, Wang Xuping, Castellani Lawrence, LeBoeuf Renee, Peterson Martha L, Spear Brett T, Lusis Aldons J
Quantitative trait locus mapping and identification of Zhx2 as a novel
regulator of plasma lipid metabolism
Circulation. Cardiovascular genetics,
2010; 3(1):
60-7.
Weinstein Michael M, Yin Liya, Tu Yiping, Wang Xuping, Wu Xiaohui, Castellani Lawrence W, Walzem Rosemary L, Lusis Aldons J, Fong Loren G, Beigneux Anne P, Young Stephen G
Chylomicronemia elicits atherosclerosis in mice--brief report
Arteriosclerosis, thrombosis, and vascular biology,
2010; 30(1):
20-3.
Woo Jennifer M P, Lin Zhuofeng, Navab Mohamad, Van Dyck Casey, Trejo-Lopez Yvette, Woo Krystal M T, Li Hongyun, Castellani Lawrence W, Wang Xuping, Iikuni Noriko, Rullo Ornella J, Wu Hui, La Cava Antonio, Fogelman Alan M, Lusis Aldons J, Tsao Betty P
Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like
manifestations in a murine lupus model of accelerated atherosclerosis
Arthritis research & therapy,
2010; 12(3):
R93.
Yang Xia, Deignan Joshua L, Qi Hongxiu, Zhu Jun, Qian Su, Zhong Judy, Torosyan Gevork, Majid Sana, Falkard Brie, Kleinhanz Robert R, Karlsson Jenny, Castellani Lawrence W, Mumick Sheena, Wang Kai, Xie Tao, Coon Michael, Zhang Chunsheng, Estrada-Smith Daria, Farber Charles R, Wang Susanna S, van Nas Atila, Ghazalpour Anatole, Zhang Bin, Macneil Douglas J, Lamb John R, Dipple Katrina M, Reitman Marc L, Mehrabian Margarete, Lum Pek Y, Schadt Eric E, Lusis Aldons J, Drake Thomas A
Validation of candidate causal genes for obesity that affect shared
metabolic pathways and networks
Nature genetics,
2009; 41(4):
415-23.
Feng Xuebing, Li Hongyun, Rumbin Alexis A, Wang Xuping, La Cava Antonio, Brechtelsbauer Katherine, Castellani Lawrence W, Witztum Joseph L, Lusis Aldons J, Tsao Betty P
ApoE-/-Fas-/- C57BL/6 mice: a novel murine model simultaneously
exhibits lupus nephritis, atherosclerosis, and osteopenia
Journal of lipid research,
2007; 48(4):
794-805.
Cervino Alessandra C, Li Guoya, Edwards Steve, Zhu Jun, Laurie Cathy, Tokiwa George, Lum Pek Yee, Wang Susanna, Castellani Lawrence W, Castellini Lawrence W, Lusis Aldons J, Carlson Sonia, Sachs Alan B, Schadt Eric E
Integrating QTL and high-density SNP analyses in mice to identify
Insig2 as a susceptibility gene for plasma cholesterol levels
Genomics,
2005; 86(5):
505-17.
Mehrabian Margarete, Allayee Hooman, Stockton Jirina, Lum Pek Yee, Drake Thomas A, Castellani Lawrence W, Suh Michael, Armour Christopher, Edwards Stephen, Lamb John, Lusis Aldons J, Schadt Eric E
Integrating genotypic and expression data in a segregating mouse
population to identify 5-lipoxygenase as a susceptibility gene for
obesity and bone traits
Nature genetics,
2005; 37(11):
1224-33.
Sheth Sonal S, Castellani Lawrence W, Chari Soumya, Wagg Cory, Thipphavong Christopher K, Bodnar Jackie S, Tontonoz Peter, Attie Alan D, Lopaschuk Gary D, Lusis Aldons J
Thioredoxin-interacting protein deficiency disrupts the
fasting-feeding metabolic transition
Journal of lipid research,
2005; 46(1):
123-34.
Wang Xuping, Gargalovic Peter, Wong Jack, Gu Jennifer L, Wu Xiaohui, Qi Hongxiu, Wen Pingzi, Xi Li, Tan Bing, Gogliotti Rocky, Castellani Lawrence W, Chatterjee Aurobindo, Lusis Aldons J
Hyplip2, a new gene for combined hyperlipidemia and increased
atherosclerosis
Arteriosclerosis, thrombosis, and vascular biology,
2004; 24(10):
1928-34.
Bodnar Jackie S, Chatterjee Aurobindo, Castellani Lawrence W, Ross David A, Ohmen Jeffrey, Cavalcoli James, Wu Chenyan, Dains Katherine M, Catanese Joe, Chu Michael, Sheth Sonal S, Charugundla Kanti, Demant Peter, West David B, de Jong Pieter, Lusis Aldons J
Positional cloning of the combined hyperlipidemia gene Hyplip1
Nature genetics,
2002; 30(1):
110-6.