Karen Reue

Title(s)Department Vice Chair, Human Genetics
SchoolMedicine
vCardDownload vCard
    Other Positions
    Title(s)Professor, Human Genetics

    Title(s)Professor, Medicine


    Collapse Research 
    Collapse Research Activities and Funding
    A novel gene and mechanisms for statin-induced myopathy in the mouse
    NIH R21AR077782Sep 17, 2020 - Aug 31, 2022
    Role: Principal Investigator
    Sex Differences in the Metabolic Syndrome
    NIH U54DK120342Sep 20, 2018 - Jul 31, 2023
    Role: Principal Investigator
    Lipid Droplets: Metabolic Consequences of the Storage of Neutral Lipids
    NIH R13DK089765Jul 7, 2010 - Jun 30, 2011
    Role: Principal Investigator
    X chromosome dosage and metabolic disease
    NIH R56DK083561Jul 1, 2010 - Aug 31, 2017
    Role: Principal Investigator
    Sex differences in obesity and metabolic disease
    NIH R01DK083561Jul 1, 2010 - Mar 31, 2016
    Role: Co-Principal Investigator
    XF24-3 Extracellular Flux Analyzer
    NIH S10RR026744May 13, 2010 - May 12, 2011
    Role: Principal Investigator
    Characterization of Diet1, a hypercholesterolemia resistance gene
    NIH R01HL102661Apr 15, 2010 - Jan 31, 2015
    Role: Principal Investigator
    Validation of C. elegans "fat genes" in the mouse
    NIH R21DK067349Apr 1, 2004 - Mar 31, 2006
    Role: Principal Investigator
    ISOLATION OF A HYPERCHOLESTEROLEMIA RESISTANCE GENE
    NIH R01HL058627May 1, 1998 - Apr 30, 2004
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gene Regulation and Mitochondrial Activity During White and Brown Adipogenesis Are Modulated by KDM5 Histone Demethylase. J Endocr Soc. 2024 Feb 19; 8(4):bvae029. Vergnes L, Wiese CB, Zore T, Riestenberg C, Avetisyan R, Reue K. PMID: 38425435; PMCID: PMC10904225.
      View in: PubMed   Mentions:
    2. The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis. J Biol Chem. 2024 Mar; 300(3):105702. Acevedo A, Jones AE, Danna BT, Turner R, Montales KP, Benincá C, Reue K, Shirihai OS, Stiles L, Wallace M, Wang Y, Bertholet AM, Divakaruni AS. PMID: 38301896; PMCID: PMC10910128.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. The role of gonadal hormones and sex chromosomes in sex-dependent effects of early nutrition on metabolic health. Front Endocrinol (Lausanne). 2023; 14:1304050. Christians JK, Reue K. PMID: 38189044; PMCID: PMC10770830.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Feeding neurons integrate metabolic and reproductive states in mice. iScience. 2023 Oct 20; 26(10):107918. Massa MG, Scott RL, Cara AL, Cortes LR, Vander PB, Sandoval NP, Park JW, Ali SL, Velez LM, Wang HB, Ati SS, Tesfaye B, Reue K, van Veen JE, Seldin MM, Correa SM. PMID: 37817932; PMCID: PMC10561062.
      View in: PubMed   Mentions: 1  
    5. The impact of chromosomal sex on cardiometabolic health and disease. Trends Endocrinol Metab. 2023 10; 34(10):652-665. Wiese CB, Avetisyan R, Reue K. PMID: 37598068.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    6. The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis. bioRxiv. 2023 Aug 16. Acevedo A, Jones AE, Danna BT, Turner R, Montales KP, Benincá C, Reue K, Shirihai OS, Stiles L, Wallace M, Wang Y, Bertholet AM, Divakaruni AS. PMID: 37645724; PMCID: PMC10461965.
      View in: PubMed   Mentions:
    7. Inclusion of Sex as a Biological Variable in Biomedical Sciences at the Undergraduate Level and Beyond. J Womens Health (Larchmt). 2023 08; 32(8):891-896. Reue K, Arnold AP. PMID: 37585516; PMCID: PMC10457603.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    8. Author Correction: Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits. Nat Metab. 2023 Mar; 5(3):530. Salisbury DA, Casero D, Zhang Z, Wang D, Kim J, Wu X, Vergnes L, Mirza AH, Leon-Mimila P, Williams KJ, Huertas-Vazquez A, Jaffrey SR, Reue K, Chen J, Sallam T. PMID: 36814000.
      View in: PubMed   Mentions:    Fields:    
    9. A "Four Core Genotypes" rat model to distinguish mechanisms underlying sex-biased phenotypes and diseases. bioRxiv. 2023 Feb 10. Arnold AP, Chen X, Grzybowski MN, Ryan JM, Sengelaub DR, Mohanroy T, Furlan VA, Grisham W, Malloy L, Takizawa A, Wiese CB, Vergnes L, Skaletsky H, Page DC, Reue K, Harley VR, Dwinell MR, Geurts AM. PMID: 36798326; PMCID: PMC9934672.
      View in: PubMed   Mentions:
    10. Feeding Neurons Integrate Metabolic and Reproductive States in Mice. bioRxiv. 2023 Jan 26. Massa MG, Scott RL, Cara AL, Cortes LR, Sandoval NP, Park JW, Ali S, Velez LM, Tesfaye B, Reue K, van Veen JE, Seldin M, Correa SM. PMID: 36747631; PMCID: PMC9900829.
      View in: PubMed   Mentions:
    11. CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization. Nature. 2023 01; 613(7942):160-168. Qian K, Tol MJ, Wu J, Uchiyama LF, Xiao X, Cui L, Bedard AH, Weston TA, Rajendran PS, Vergnes L, Shimanaka Y, Yin Y, Jami-Alahmadi Y, Cohn W, Bajar BT, Lin CH, Jin B, DeNardo LA, Black DL, Whitelegge JP, Wohlschlegel JA, Reue K, Shivkumar K, Chen FJ, Young SG, Li P, Tontonoz P. PMID: 36477540; PMCID: PMC9995219.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    12. Proteome-wide systems genetics identifies UFMylation as a regulator of skeletal muscle function. Elife. 2022 12 06; 11. Molendijk J, Blazev R, Mills RJ, Ng YK, Watt KI, Chau D, Gregorevic P, Crouch PJ, Hilton JBW, Lisowski L, Zhang P, Reue K, Lusis AJ, Hudson JE, James DE, Seldin MM, Parker BL. PMID: 36472367; PMCID: PMC9833826.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    13. Ciliary neurotrophic factor-mediated neuroprotection involves enhanced glycolysis and anabolism in degenerating mouse retinas. Nat Commun. 2022 11 17; 13(1):7037. Do Rhee K, Wang Y, Ten Hoeve J, Stiles L, Nguyen TTT, Zhang X, Vergnes L, Reue K, Shirihai O, Bok D, Yang XJ. PMID: 36396639; PMCID: PMC9672129.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    14. Chromosomal and gonadal sex drive sex differences in lipids and hepatic gene expression in response to hypercholesterolemia and statin treatment. Biol Sex Differ. 2022 Nov 04; 13(1):63. Wiese CB, Agle ZW, Zhang P, Reue K. PMID: 36333813; PMCID: PMC9636767.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    15. Simultaneous monitoring of mouse grip strength, force profile, and cumulative force profile distinguishes muscle physiology following surgical, pharmacologic and diet interventions. Sci Rep. 2022 09 30; 12(1):16428. Munier JJ, Pank JT, Severino A, Wang H, Zhang P, Vergnes L, Reue K. PMID: 36180720; PMCID: PMC9525296.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    16. Sex differences in heart mitochondria regulate diastolic dysfunction. Nat Commun. 2022 07 04; 13(1):3850. Cao Y, Vergnes L, Wang YC, Pan C, Chella Krishnan K, Moore TM, Rosa-Garrido M, Kimball TH, Zhou Z, Charugundla S, Rau CD, Seldin MM, Wang J, Wang Y, Vondriska TM, Reue K, Lusis AJ. PMID: 35787630; PMCID: PMC9253085.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    17. Author Correction: Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits. Nat Metab. 2022 Jul; 4(7):960. Salisbury DA, Casero D, Zhang Z, Wang D, Kim J, Wu X, Vergnes L, Mirza AH, Leon-Mimila P, Williams KJ, Huertas-Vazquez A, Jaffrey SR, Reue K, Chen J, Sallam T. PMID: 35851380.
      View in: PubMed   Mentions:    Fields:    
    18. Illuminating the Mechanisms Underlying Sex Differences in Cardiovascular Disease. Circ Res. 2022 06 10; 130(12):1747-1762. Reue K, Wiese CB. PMID: 35679362; PMCID: PMC9202078.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    19. Relative contributions of sex hormones, sex chromosomes, and gonads to sex differences in tissue gene regulation. Genome Res. 2022 05; 32(5):807-824. Blencowe M, Chen X, Zhao Y, Itoh Y, McQuillen CN, Han Y, Shou BL, McClusky R, Reue K, Arnold AP, Yang X. PMID: 35396276; PMCID: PMC9104702.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    20. Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2. Acta Pharm Sin B. 2022 Apr; 12(4):1624-1635. Aliyari SR, Ghaffari AA, Pernet O, Parvatiyar K, Wang Y, Gerami H, Tong AJ, Vergnes L, Takallou A, Zhang A, Wei X, Chilin LD, Wu Y, Semenkovich CF, Reue K, Smale ST, Lee B, Cheng G. PMID: 35251918; PMCID: PMC8883762.
      View in: PubMed   Mentions: 7  
    21. Female and male mice have differential longterm cardiorenal outcomes following a matched degree of ischemia-reperfusion acute kidney injury. Sci Rep. 2022 01 12; 12(1):643. Soranno DE, Baker P, Kirkbride-Romeo L, Wennersten SA, Ding K, Keith B, Cavasin MA, Altmann C, Bagchi RA, Haefner KR, Montford J, Gist KM, Vergnes L, Reue K, He Z, Elajaili H, Okamura K, Nozik E, McKinsey TA, Faubel S. PMID: 35022484; PMCID: PMC8755805.
      View in: PubMed   Mentions: 10     Fields:    
    22. Sex-specific genetic regulation of adipose mitochondria and metabolic syndrome by Ndufv2. Nat Metab. 2021 11; 3(11):1552-1568. Chella Krishnan K, Vergnes L, Acín-Pérez R, Stiles L, Shum M, Ma L, Mouisel E, Pan C, Moore TM, Péterfy M, Romanoski CE, Reue K, Björkegren JLM, Laakso M, Liesa M, Lusis AJ. PMID: 34697471; PMCID: PMC8909918.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    23. Lipin 1 modulates mRNA splicing during fasting adaptation in liver. JCI Insight. 2021 09 08; 6(17). Wang H, Chan TW, Vashisht AA, Drew BG, Calkin AC, Harris TE, Wohlschlegel JA, Xiao X, Reue K. PMID: 34494556; PMCID: PMC8492312.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    24. The middle lipin domain adopts a membrane-binding dimeric protein fold. Nat Commun. 2021 08 05; 12(1):4718. Gu W, Gao S, Wang H, Fleming KD, Hoffmann RM, Yang JW, Patel NM, Choi YM, Burke JE, Reue K, Airola MV. PMID: 34354069; PMCID: PMC8342540.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    25. Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits. Nat Metab. 2021 07; 3(7):940-953. Salisbury DA, Casero D, Zhang Z, Wang D, Kim J, Wu X, Vergnes L, Mirza AH, Leon-Mimila P, Williams KJ, Huertas-Vazquez A, Jaffrey SR, Reue K, Chen J, Sallam T. PMID: 34282353; PMCID: PMC8422857.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    26. Sex- and Gender-Based Pharmacological Response to Drugs. Pharmacol Rev. 2021 04; 73(2):730-762. Mauvais-Jarvis F, Berthold HK, Campesi I, Carrero JJ, Dakal S, Franconi F, Gouni-Berthold I, Heiman ML, Kautzky-Willer A, Klein SL, Murphy A, Regitz-Zagrosek V, Reue K, Rubin JB. PMID: 33653873; PMCID: PMC7938661.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    27. Creatine kinase B controls futile creatine cycling in thermogenic fat. Nature. 2021 02; 590(7846):480-485. Rahbani JF, Roesler A, Hussain MF, Samborska B, Dykstra CB, Tsai L, Jedrychowski MP, Vergnes L, Reue K, Spiegelman BM, Kazak L. PMID: 33597756; PMCID: PMC8647628.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    28. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, et al. PMID: 33634751; PMCID: PMC7996087.
      View in: PubMed   Mentions: 870     Fields:    Translation:HumansAnimalsCells
    29. Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis. Mol Syst Biol. 2021 01; 17(1):e9684. Norheim F, Chella Krishnan K, Bjellaas T, Vergnes L, Pan C, Parks BW, Meng Y, Lang J, Ward JA, Reue K, Mehrabian M, Gundersen TE, Péterfy M, Dalen KT, Drevon CA, Hui ST, Lusis AJ, Seldin MM. PMID: 33417276; PMCID: PMC7792507.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    30. Isolation and functional analysis of peridroplet mitochondria from murine brown adipose tissue. STAR Protoc. 2021 03 19; 2(1):100243. Ngo J, Benador IY, Brownstein AJ, Vergnes L, Veliova M, Shum M, Acín-Pérez R, Reue K, Shirihai OS, Liesa M. PMID: 33458705; PMCID: PMC7797917.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    31. X chromosome dosage of histone demethylase KDM5C determines sex differences in adiposity. J Clin Invest. 2020 11 02; 130(11):5688-5702. Link JC, Wiese CB, Chen X, Avetisyan R, Ronquillo E, Ma F, Guo X, Yao J, Allison M, Chen YI, Rotter JI, El-Sayed Moustafa JS, Small KS, Iwase S, Pellegrini M, Vergnes L, Arnold AP, Reue K. PMID: 32701509; PMCID: PMC7598065.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    32. Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. J Biol Chem. 2020 10 30; 295(44):15054-15069. Vergnes L, Lin JY, Davies GR, Church CD, Reue K. PMID: 32855239; PMCID: PMC7606676.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    33. Estrogen receptor α controls metabolism in white and brown adipocytes by regulating Polg1 and mitochondrial remodeling. Sci Transl Med. 2020 08 05; 12(555). Zhou Z, Moore TM, Drew BG, Ribas V, Wanagat J, Civelek M, Segawa M, Wolf DM, Norheim F, Seldin MM, Strumwasser AR, Whitney KA, Lester E, Reddish BR, Vergnes L, Reue K, Rajbhandari P, Tontonoz P, Lee J, Mahata SK, Hewitt SC, Shirihai O, Gastonbury C, Small KS, Laakso M, Jensen J, Lee S, Drevon CA, Korach KS, Lusis AJ, Hevener AL. PMID: 32759275; PMCID: PMC8212422.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    34. A novel approach to measure mitochondrial respiration in frozen biological samples. EMBO J. 2020 07 01; 39(13):e104073. Acin-Perez R, Benador IY, Petcherski A, Veliova M, Benavides GA, Lagarrigue S, Caudal A, Vergnes L, Murphy AN, Karamanlidis G, Tian R, Reue K, Wanagat J, Sacks H, Amati F, Darley-Usmar VM, Liesa M, Divakaruni AS, Stiles L, Shirihai OS. PMID: 32432379; PMCID: PMC7327496.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    35. Publisher Correction: Crystal structure of a lipin/Pah phosphatidic acid phosphatase. Nat Commun. 2020 Apr 02; 11(1):1734. Khayyo VI, Hoffmann RM, Wang H, Bell JA, Burke JE, Reue K, Airola MV. PMID: 32242008; PMCID: PMC7118079.
      View in: PubMed   Mentions:    Fields:    
    36. Crystal structure of a lipin/Pah phosphatidic acid phosphatase. Nat Commun. 2020 03 11; 11(1):1309. Khayyo VI, Hoffmann RM, Wang H, Bell JA, Burke JE, Reue K, Airola MV. PMID: 32161260; PMCID: PMC7066176.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    37. Isoquinoline thiosemicarbazone displays potent anticancer activity with in vivo efficacy against aggressive leukemias. RSC Med Chem. 2020 Mar 01; 11(3):392-410. Sun DL, Poddar S, Pan RD, Rosser EW, Abt ER, Van Valkenburgh J, Le TM, Lok V, Hernandez SP, Song J, Li J, Turlik A, Chen X, Cheng CA, Chen W, Mona CE, Stuparu AD, Vergnes L, Reue K, Damoiseaux R, Zink JI, Czernin J, Donahue TR, Houk KN, Jung ME, Radu CG. PMID: 33479645; PMCID: PMC7593890.
      View in: PubMed   Mentions: 3  
    38. Deficiency in ZMPSTE24 and resulting farnesyl-prelamin A accumulation only modestly affect mouse adipose tissue stores. J Lipid Res. 2020 03; 61(3):413-421. Heizer PJ, Yang Y, Tu Y, Kim PH, Chen NY, Hu Y, Yoshinaga Y, de Jong PJ, Vergnes L, Morales JE, Li RL, Jackson N, Reue K, Young SG, Fong LG. PMID: 31941672; PMCID: PMC7053845.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    39. Single cell analysis reveals immune cell-adipocyte crosstalk regulating the transcription of thermogenic adipocytes. Elife. 2019 10 23; 8. Rajbhandari P, Arneson D, Hart SK, Ahn IS, Diamante G, Santos LC, Zaghari N, Feng AC, Thomas BJ, Vergnes L, Lee SD, Rajbhandari AK, Reue K, Smale ST, Yang X, Tontonoz P. PMID: 31644425; PMCID: PMC6837845.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    40. Sex-specific metabolic functions of adipose Lipocalin-2. Mol Metab. 2019 12; 30:30-47. Chella Krishnan K, Sabir S, Shum M, Meng Y, Acín-Pérez R, Lang JM, Floyd RR, Vergnes L, Seldin MM, Fuqua BK, Jayasekera DW, Nand SK, Anum DC, Pan C, Stiles L, Péterfy M, Reue K, Liesa M, Lusis AJ. PMID: 31767179; PMCID: PMC6812340.
      View in: PubMed   Mentions: 20     Fields:    Translation:Animals
    41. Diesel Exhaust Induces Mitochondrial Dysfunction, Hyperlipidemia, and Liver Steatosis. Arterioscler Thromb Vasc Biol. 2019 09; 39(9):1776-1786. Yin F, Gupta R, Vergnes L, Driscoll WS, Ricks J, Ramanathan G, Stewart JA, Shih DM, Faull KF, Beaven SW, Lusis AJ, Reue K, Rosenfeld ME, Araujo JA. PMID: 31340670; PMCID: PMC6703953.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    42. Stimulation of Hair Growth by Small Molecules that Activate Autophagy. Cell Rep. 2019 06 18; 27(12):3413-3421.e3. Chai M, Jiang M, Vergnes L, Fu X, de Barros SC, Doan NB, Huang W, Chu J, Jiao J, Herschman H, Crooks GM, Reue K, Huang J. PMID: 31216464.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    43. XX sex chromosome complement promotes atherosclerosis in mice. Nat Commun. 2019 06 14; 10(1):2631. AlSiraj Y, Chen X, Thatcher SE, Temel RE, Cai L, Blalock E, Katz W, Ali HM, Petriello M, Deng P, Morris AJ, Wang X, Lusis AJ, Arnold AP, Reue K, Thompson K, Tso P, Cassis LA. PMID: 31201301; PMCID: PMC6643208.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    44. Noggin depletion in adipocytes promotes obesity in mice. Mol Metab. 2019 07; 25:50-63. Blázquez-Medela AM, Jumabay M, Rajbhandari P, Sallam T, Guo Y, Yao J, Vergnes L, Reue K, Zhang L, Yao Y, Fogelman AM, Tontonoz P, Lusis AJ, Wu X, Boström KI. PMID: 31027994; PMCID: PMC6600080.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    45. Mammalian lipin phosphatidic acid phosphatases in lipid synthesis and beyond: metabolic and inflammatory disorders. J Lipid Res. 2019 04; 60(4):728-733. Reue K, Wang H. PMID: 30804008; PMCID: PMC6446709.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    46. PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. Antioxidants (Basel). 2019 Jan 11; 8(1). Shih DM, Meng Y, Sallam T, Vergnes L, Shu ML, Reue K, Tontonoz P, Fogelman AM, Lusis AJ, Reddy ST. PMID: 30641857; PMCID: PMC6356528.
      View in: PubMed   Mentions: 11  
    47. Gene-by-Sex Interactions in Mitochondrial Functions and Cardio-Metabolic Traits. Cell Metab. 2019 04 02; 29(4):932-949.e4. Norheim F, Hasin-Brumshtein Y, Vergnes L, Chella Krishnan K, Pan C, Seldin MM, Hui ST, Mehrabian M, Zhou Z, Gupta S, Parks BW, Walch A, Reue K, Hofmann SM, Arnold AP, Lusis AJ. PMID: 30639359; PMCID: PMC6447452.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    48. Lipin 2/3 phosphatidic acid phosphatases maintain phospholipid homeostasis to regulate chylomicron synthesis. J Clin Invest. 2019 01 02; 129(1):281-295. Zhang P, Csaki LS, Ronquillo E, Baufeld LJ, Lin JY, Gutierrez A, Dwyer JR, Brindley DN, Fong LG, Tontonoz P, Young SG, Reue K. PMID: 30507612; PMCID: PMC6307960.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    49. Deciphering the Role of Lipid Droplets in Cardiovascular Disease: A Report From the 2017 National Heart, Lung, and Blood Institute Workshop. Circulation. 2018 07 17; 138(3):305-315. Goldberg IJ, Reue K, Abumrad NA, Bickel PE, Cohen S, Fisher EA, Galis ZS, Granneman JG, Lewandowski ED, Murphy R, Olive M, Schaffer JE, Schwartz-Longacre L, Shulman GI, Walther TC, Chen J. PMID: 30012703; PMCID: PMC6056021.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    50. KDM4B protects against obesity and metabolic dysfunction. Proc Natl Acad Sci U S A. 2018 06 12; 115(24):E5566-E5575. Cheng Y, Yuan Q, Vergnes L, Rong X, Youn JY, Li J, Yu Y, Liu W, Cai H, Lin JD, Tontonoz P, Hong C, Reue K, Wang CY. PMID: 29844188; PMCID: PMC6004484.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    51. Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate. Nat Commun. 2018 05 15; 9(1):1916. Li TY, Song L, Sun Y, Li J, Yi C, Lam SM, Xu D, Zhou L, Li X, Yang Y, Zhang CS, Xie C, Huang X, Shui G, Lin SY, Reue K, Lin SC. PMID: 29765047; PMCID: PMC5953937.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    52. NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes. Cell Metab. 2018 May 01; 27(5):1055-1066.e3. He C, Weston TA, Jung RS, Heizer P, Larsson M, Hu X, Allan CM, Tontonoz P, Reue K, Beigneux AP, Ploug M, Holme A, Kilburn M, Guagliardo P, Ford DA, Fong LG, Young SG, Jiang H. PMID: 29719224; PMCID: PMC5945212.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    53. A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism. Cell Metab. 2018 May 01; 27(5):1138-1155.e6. Seldin MM, Koplev S, Rajbhandari P, Vergnes L, Rosenberg GM, Meng Y, Pan C, Phuong TMN, Gharakhanian R, Che N, Mäkinen S, Shih DM, Civelek M, Parks BW, Kim ED, Norheim F, Chella Krishnan K, Hasin-Brumshtein Y, Mehrabian M, Laakso M, Drevon CA, Koistinen HA, Tontonoz P, Reue K, Cantor RM, Björkegren JLM, Lusis AJ. PMID: 29719227; PMCID: PMC5935137.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    54. Sex differences in obesity, lipid metabolism, and inflammation-A role for the sex chromosomes? Mol Metab. 2018 09; 15:35-44. Zore T, Palafox M, Reue K. PMID: 29706320; PMCID: PMC6066740.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    55. Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress. J Biol Chem. 2018 03 30; 293(13):4735-4751. Zhou Z, Ribas V, Rajbhandari P, Drew BG, Moore TM, Fluitt AH, Reddish BR, Whitney KA, Georgia S, Vergnes L, Reue K, Liesa M, Shirihai O, van der Bliek AM, Chi NW, Mahata SK, Tiano JP, Hewitt SC, Tontonoz P, Korach KS, Mauvais-Jarvis F, Hevener AL. PMID: 29378845; PMCID: PMC5880140.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    56. Integration of Multi-omics Data from Mouse Diversity Panel Highlights Mitochondrial Dysfunction in Non-alcoholic Fatty Liver Disease. Cell Syst. 2018 Jan 24; 6(1):103-115.e7. Chella Krishnan K, Kurt Z, Barrere-Cain R, Sabir S, Das A, Floyd R, Vergnes L, Zhao Y, Che N, Charugundla S, Qi H, Zhou Z, Meng Y, Pan C, Seldin MM, Norheim F, Hui S, Reue K, Lusis AJ, Yang X. PMID: 29361464; PMCID: PMC5799036.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    57. Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants. J Lipid Res. 2018 03; 59(3):429-438. Lee JM, Ong JR, Vergnes L, de Aguiar Vallim TQ, Nolan J, Cantor RM, Walters JRF, Reue K. PMID: 29295820; PMCID: PMC5832924.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    58. Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells. Oncotarget. 2018 Jan 09; 9(3):4044-4060. Hodeib M, Ogrodzinski MP, Vergnes L, Reue K, Karlan BY, Lunt SY, Aspuria PP. PMID: 29423103; PMCID: PMC5790520.
      View in: PubMed   Mentions: 7     Fields:    
    59. IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure. Cell. 2018 01 11; 172(1-2):218-233.e17. Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T, Wang B, Sandhu J, Seldin MM, Lusis AJ, Fong LG, Katz M, Lee R, Young SG, Reue K, Smale ST, Tontonoz P. PMID: 29249357; PMCID: PMC5766418.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    60. Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. Elife. 2017 12 12; 6. Nakano H, Minami I, Braas D, Pappoe H, Wu X, Sagadevan A, Vergnes L, Fu K, Morselli M, Dunham C, Ding X, Stieg AZ, Gimzewski JK, Pellegrini M, Clark PM, Reue K, Lusis AJ, Ribalet B, Kurdistani SK, Christofk H, Nakatsuji N, Nakano A. PMID: 29231167; PMCID: PMC5726851.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    61. How lipid droplets "TAG" along: Glycerolipid synthetic enzymes and lipid storage. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct; 1862(10 Pt B):1131-1145. Wang H, Airola MV, Reue K. PMID: 28642195; PMCID: PMC5688854.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansAnimalsCells
    62. Genetic Basis for Sex Differences in Obesity and Lipid Metabolism. Annu Rev Nutr. 2017 08 21; 37:225-245. Link JC, Reue K. PMID: 28628359; PMCID: PMC5759759.
      View in: PubMed   Mentions: 126     Fields:    Translation:HumansAnimalsCells
    63. A Guide for the Design of Pre-clinical Studies on Sex Differences in Metabolism. Cell Metab. 2017 Jun 06; 25(6):1216-1230. Mauvais-Jarvis F, Arnold AP, Reue K. PMID: 28591630; PMCID: PMC5516948.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimals
    64. Lipin proteins and glycerolipid metabolism: Roles at the ER membrane and beyond. Biochim Biophys Acta Biomembr. 2017 Sep; 1859(9 Pt B):1583-1595. Zhang P, Reue K. PMID: 28411173; PMCID: PMC5688847.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    65. Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia. N Engl J Med. 2017 04 27; 376(17):1647-1658. Beigneux AP, Miyashita K, Ploug M, Blom DJ, Ai M, Linton MF, Khovidhunkit W, Dufour R, Garg A, McMahon MA, Pullinger CR, Sandoval NP, Hu X, Allan CM, Larsson M, Machida T, Murakami M, Reue K, Tontonoz P, Goldberg IJ, Moulin P, Charrière S, Fong LG, Nakajima K, Young SG. PMID: 28402248; PMCID: PMC5555413.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    66. Sex Hormones and Sex Chromosomes Cause Sex Differences in the Development of Cardiovascular Diseases. Arterioscler Thromb Vasc Biol. 2017 05; 37(5):746-756. Arnold AP, Cassis LA, Eghbali M, Reue K, Sandberg K. PMID: 28279969; PMCID: PMC5437981.
      View in: PubMed   Mentions: 129     Fields:    Translation:HumansAnimalsCells
    67. Sex differences in obesity: X chromosome dosage as a risk factor for increased food intake, adiposity and co-morbidities. Physiol Behav. 2017 Jul 01; 176:174-182. Reue K. PMID: 28284880; PMCID: PMC5444325.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    68. RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs. J Clin Invest. 2017 Mar 01; 127(3):987-1004. Wang J, Rajbhandari P, Damianov A, Han A, Sallam T, Waki H, Villanueva CJ, Lee SD, Nielsen R, Mandrup S, Reue K, Young SG, Whitelegge J, Saez E, Black DL, Tontonoz P. PMID: 28192372; PMCID: PMC5330726.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    69. Diet, gonadal sex, and sex chromosome complement influence white adipose tissue miRNA expression. BMC Genomics. 2017 01 17; 18(1):89. Link JC, Hasin-Brumshtein Y, Cantor RM, Chen X, Arnold AP, Lusis AJ, Reue K. PMID: 28095800; PMCID: PMC5240420.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    70. StarD7 Protein Deficiency Adversely Affects the Phosphatidylcholine Composition, Respiratory Activity, and Cristae Structure of Mitochondria. J Biol Chem. 2016 Nov 25; 291(48):24880-24891. Horibata Y, Ando H, Zhang P, Vergnes L, Aoyama C, Itoh M, Reue K, Sugimoto H. PMID: 27694445; PMCID: PMC5122760.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    71. Simulated microgravity enhances oligodendrocyte mitochondrial function and lipid metabolism. J Neurosci Res. 2016 12; 94(12):1434-1450. Espinosa-Jeffrey A, Nguyen K, Kumar S, Toshimasa O, Hirose R, Reue K, Vergnes L, Kinchen J, Vellis J. PMID: 27680492; PMCID: PMC7324008.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    72. Adipocyte Browning and Higher Mitochondrial Function in Periadrenal But Not SC Fat in Pheochromocytoma. J Clin Endocrinol Metab. 2016 11; 101(11):4440-4448. Vergnes L, Davies GR, Lin JY, Yeh MW, Livhits MJ, Harari A, Symonds ME, Sacks HS, Reue K. PMID: 27575944; PMCID: PMC5095230.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    73. Prdm4 induction by the small molecule butein promotes white adipose tissue browning. Nat Chem Biol. 2016 07; 12(7):479-81. Song NJ, Choi S, Rajbhandari P, Chang SH, Kim S, Vergnes L, Kwon SM, Yoon JH, Lee S, Ku JM, Lee JS, Reue K, Koo SH, Tontonoz P, Park KW. PMID: 27159578; PMCID: PMC4912433.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    74. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J. 2016 Apr 15; 35(8):899. Zhang J, Khvorostov I, Hong JS, Oktay Y, Vergnes L, Nuebel E, Wahjudi PN, Setoguchi K, Wang G, Do A, Jung HJ, McCaffery JM, Kurland IJ, Reue K, Lee WN, Koehler CM, Teitell MA. PMID: 27084758; PMCID: PMC4972131.
      View in: PubMed   Mentions: 11     Fields:    
    75. Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females. Sci Transl Med. 2016 Apr 13; 8(334):334ra54. Ribas V, Drew BG, Zhou Z, Phun J, Kalajian NY, Soleymani T, Daraei P, Widjaja K, Wanagat J, de Aguiar Vallim TQ, Fluitt AH, Bensinger S, Le T, Radu C, Whitelegge JP, Beaven SW, Tontonoz P, Lusis AJ, Parks BW, Vergnes L, Reue K, Singh H, Bopassa JC, Toro L, Stefani E, Watt MJ, Schenk S, Akerstrom T, Kelly M, Pedersen BK, Hewitt SC, Korach KS, Hevener AL. PMID: 27075628; PMCID: PMC4934679.
      View in: PubMed   Mentions: 107     Fields:    Translation:HumansAnimalsCells
    76. The importance of having two X chromosomes. Philos Trans R Soc Lond B Biol Sci. 2016 Feb 19; 371(1688):20150113. Arnold AP, Reue K, Eghbali M, Vilain E, Chen X, Ghahramani N, Itoh Y, Li J, Link JC, Ngun T, Williams-Burris SM. PMID: 26833834; PMCID: PMC4785899.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    77. SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression. J Lipid Res. 2016 Mar; 57(3):410-21. Vergnes L, Chin RG, de Aguiar Vallim T, Fong LG, Osborne TF, Young SG, Reue K. PMID: 26685326; PMCID: PMC4766990.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    78. Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling. Cell. 2015 Dec 17; 163(7):1716-29. York AG, Williams KJ, Argus JP, Zhou QD, Brar G, Vergnes L, Gray EE, Zhen A, Wu NC, Yamada DH, Cunningham CR, Tarling EJ, Wilks MQ, Casero D, Gray DH, Yu AK, Wang ES, Brooks DG, Sun R, Kitchen SG, Wu TT, Reue K, Stetson DB, Bensinger SJ. PMID: 26686653; PMCID: PMC4783382.
      View in: PubMed   Mentions: 214     Fields:    Translation:HumansAnimalsCells
    79. Women in Metabolism: Part 3. Cell Metab. 2015 Dec 01; 22(6):949-53. Ashcroft F, Pearce E, Partridge L, Suomalainen A, Brunet A, Schulze A, Tseng YH, Sethi JK, Reue K, Kingwell B, McNally E, Cnop M, Hevener AL, Diano S. PMID: 26636490.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    80. ANGPTL4 mediates shuttling of lipid fuel to brown adipose tissue during sustained cold exposure. Elife. 2015 Oct 17; 4. Dijk W, Heine M, Vergnes L, Boon MR, Schaart G, Hesselink MK, Reue K, van Marken Lichtenbelt WD, Olivecrona G, Rensen PC, Heeren J, Kersten S. PMID: 26476336; PMCID: PMC4709329.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    81. Increased Expression of Beige/Brown Adipose Markers from Host and Breast Cancer Cells Influence Xenograft Formation in Mice. Mol Cancer Res. 2016 Jan; 14(1):78-92. Singh R, Parveen M, Basgen JM, Fazel S, Meshesha MF, Thames EC, Moore B, Martinez L, Howard CB, Vergnes L, Reue K, Pervin S. PMID: 26464213; PMCID: PMC4749269.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    82. Dietary fructose aggravates the pathobiology of traumatic brain injury by influencing energy homeostasis and plasticity. J Cereb Blood Flow Metab. 2016 05; 36(5):941-53. Agrawal R, Noble E, Vergnes L, Ying Z, Reue K, Gomez-Pinilla F. PMID: 26661172; PMCID: PMC4853835.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    83. Sex differences in diurnal rhythms of food intake in mice caused by gonadal hormones and complement of sex chromosomes. Horm Behav. 2015 Sep; 75:55-63. Chen X, Wang L, Loh DH, Colwell CS, Taché Y, Reue K, Arnold AP. PMID: 26226656; PMCID: PMC4648666.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    84. 2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling. Cell Metab. 2015 Sep 01; 22(3):508-15. Fu X, Chin RM, Vergnes L, Hwang H, Deng G, Xing Y, Pai MY, Li S, Ta L, Fazlollahi F, Chen C, Prins RM, Teitell MA, Nathanson DA, Lai A, Faull KF, Jiang M, Clarke SG, Cloughesy TF, Graeber TG, Braas D, Christofk HR, Jung ME, Reue K, Huang J. PMID: 26190651; PMCID: PMC4663076.
      View in: PubMed   Mentions: 124     Fields:    Translation:HumansAnimalsCells
    85. Disturbed Flow Induces Autophagy, but Impairs Autophagic Flux to Perturb Mitochondrial Homeostasis. Antioxid Redox Signal. 2015 Nov 20; 23(15):1207-19. Li R, Jen N, Wu L, Lee J, Fang K, Quigley K, Lee K, Wang S, Zhou B, Vergnes L, Chen YR, Li Z, Reue K, Ann DK, Hsiai TK. PMID: 26120766; PMCID: PMC4657520.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    86. Increased high-density lipoprotein cholesterol levels in mice with XX versus XY sex chromosomes. Arterioscler Thromb Vasc Biol. 2015 Aug; 35(8):1778-86. Link JC, Chen X, Prien C, Borja MS, Hammerson B, Oda MN, Arnold AP, Reue K. PMID: 26112012; PMCID: PMC4668127.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    87. Diet1 is a regulator of fibroblast growth factor 15/19-dependent bile acid synthesis. Dig Dis. 2015; 33(3):307-13. Reue K, Lee JM, Vergnes L. PMID: 26045262; PMCID: PMC4809532.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    88. Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism. Cancer Metab. 2014; 2:21. Aspuria PP, Lunt SY, Väremo L, Vergnes L, Gozo M, Beach JA, Salumbides B, Reue K, Wiedemeyer WR, Nielsen J, Karlan BY, Orsulic S. PMID: 25671108; PMCID: PMC4322794.
      View in: PubMed   Mentions: 89  
    89. PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis. FASEB J. 2015 Apr; 29(4):1185-97. Shih DM, Yu JM, Vergnes L, Dali-Youcef N, Champion MD, Devarajan A, Zhang P, Castellani LW, Brindley DN, Jamey C, Auwerx J, Reddy ST, Ford DA, Reue K, Lusis AJ. PMID: 25477283; PMCID: PMC4396607.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    90. Adaptive thermogenesis in white adipose tissue: is lactate the new brown(ing)? Diabetes. 2014 Oct; 63(10):3175-6. Vergnes L, Reue K. PMID: 25249643; PMCID: PMC4171663.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    91. Metabolic differences in breast cancer stem cells and differentiated progeny. Breast Cancer Res Treat. 2014 Aug; 146(3):525-34. Vlashi E, Lagadec C, Vergnes L, Reue K, Frohnen P, Chan M, Alhiyari Y, Dratver MB, Pajonk F. PMID: 25007966; PMCID: PMC4131557.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    92. Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein. Neurobiol Dis. 2014 Oct; 70:204-13. Subramaniam SR, Vergnes L, Franich NR, Reue K, Chesselet MF. PMID: 25016198; PMCID: PMC4205109.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCells
    93. Lipin-1 regulates autophagy clearance and intersects with statin drug effects in skeletal muscle. Cell Metab. 2014 Aug 05; 20(2):267-79. Zhang P, Verity MA, Reue K. PMID: 24930972; PMCID: PMC4170588.
      View in: PubMed   Mentions: 84     Fields:    Translation:AnimalsCells
    94. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014 Jun 19; 510(7505):397-401. Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J. PMID: 24828042; PMCID: PMC4263271.
      View in: PubMed   Mentions: 268     Fields:    Translation:HumansAnimalsCells
    95. The GPIHBP1-LPL complex is responsible for the margination of triglyceride-rich lipoproteins in capillaries. Cell Metab. 2014 May 06; 19(5):849-60. Goulbourne CN, Gin P, Tatar A, Nobumori C, Hoenger A, Jiang H, Grovenor CR, Adeyo O, Esko JD, Goldberg IJ, Reue K, Tontonoz P, Bensadoun A, Beigneux AP, Young SG, Fong LG. PMID: 24726386; PMCID: PMC4143151.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    96. Regulation of bile acid homeostasis by the intestinal Diet1-FGF15/19 axis. Curr Opin Lipidol. 2014 Apr; 25(2):140-7. Reue K, Lee JM, Vergnes L. PMID: 24535283; PMCID: PMC4497822.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    97. Follistatin promotes adipocyte differentiation, browning, and energy metabolism. J Lipid Res. 2014 Mar; 55(3):375-84. Braga M, Reddy ST, Vergnes L, Pervin S, Grijalva V, Stout D, David J, Li X, Tomasian V, Reid CB, Norris KC, Devaskar SU, Reue K, Singh R. PMID: 24443561; PMCID: PMC3934723.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    98. Lipin-1 flexes its muscle in autophagy. Cell Cycle. 2014; 13(24):3789-90. Zhang P, Reue K. PMID: 25483058; PMCID: PMC4615126.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    99. HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle. Diabetes. 2014 May; 63(5):1488-505. Drew BG, Ribas V, Le JA, Henstridge DC, Phun J, Zhou Z, Soleymani T, Daraei P, Sitz D, Vergnes L, Wanagat J, Reue K, Febbraio MA, Hevener AL. PMID: 24379352; PMCID: PMC3994950.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    100. Coupling energy homeostasis with a mechanism to support plasticity in brain trauma. Biochim Biophys Acta. 2014 Apr; 1842(4):535-46. Agrawal R, Tyagi E, Vergnes L, Reue K, Gomez-Pinilla F. PMID: 24345766.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    101. Lipin-1 and lipin-3 together determine adiposity in vivo. Mol Metab. 2014 Apr; 3(2):145-54. Csaki LS, Dwyer JR, Li X, Nguyen MH, Dewald J, Brindley DN, Lusis AJ, Yoshinaga Y, de Jong P, Fong L, Young SG, Reue K. PMID: 24634820; PMCID: PMC3953701.
      View in: PubMed   Mentions: 30     Fields:    
    102. The Sex Chromosome Trisomy mouse model of XXY and XYY: metabolism and motor performance. Biol Sex Differ. 2013 Aug 08; 4(1):15. Chen X, Williams-Burris SM, McClusky R, Ngun TC, Ghahramani N, Barseghyan H, Reue K, Vilain E, Arnold AP. PMID: 23926958; PMCID: PMC3751353.
      View in: PubMed   Mentions: 16     Fields:    
    103. PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response. Mol Metab. 2013; 2(4):405-16. Lu G, Ota A, Ren S, Franklin S, Rau CD, Ping P, Lane TF, Zhou ZH, Reue K, Lusis AJ, Vondriska T, Wang Y. PMID: 24327956; PMCID: PMC3854994.
      View in: PubMed   Mentions: 19     Fields:    
    104. Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels. Cell Metab. 2013 Jun 04; 17(6):916-928. Vergnes L, Lee JM, Chin RG, Auwerx J, Reue K. PMID: 23747249; PMCID: PMC3956443.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    105. Response to Pomozi et al's research commentary. Circ Res. 2013 May 24; 112(11):e152-3. Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, Lusis AJ. PMID: 23625949; PMCID: PMC3999040.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    106. Lipins, lipinopathies, and the modulation of cellular lipid storage and signaling. Prog Lipid Res. 2013 Jul; 52(3):305-16. Csaki LS, Dwyer JR, Fong LG, Tontonoz P, Young SG, Reue K. PMID: 23603613; PMCID: PMC3830937.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    107. Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat Immunol. 2013 May; 14(5):489-99. Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, Marbois BN, Komisopoulou E, Wilson EB, Osborne TF, Graeber TG, Reue K, Brooks DG, Bensinger SJ. PMID: 23563690; PMCID: PMC3652626.
      View in: PubMed   Mentions: 253     Fields:    Translation:AnimalsCells
    108. Metabolic impact of sex chromosomes. Adipocyte. 2013 Apr 01; 2(2):74-9. Link JC, Chen X, Arnold AP, Reue K. PMID: 23805402; PMCID: PMC3661109.
      View in: PubMed   Mentions: 55     Fields:    
    109. Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs. Cell Metab. 2013 Mar 05; 17(3):423-35. Villanueva CJ, Vergnes L, Wang J, Drew BG, Hong C, Tu Y, Hu Y, Peng X, Xu F, Saez E, Wroblewski K, Hevener AL, Reue K, Fong LG, Young SG, Tontonoz P. PMID: 23473036; PMCID: PMC3626567.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    110. Cell-autonomous sex determination outside of the gonad. Dev Dyn. 2013 Apr; 242(4):371-9. Arnold AP, Chen X, Link JC, Itoh Y, Reue K. PMID: 23361913; PMCID: PMC3672066.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    111. An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Res. 2013 May 01; 73(9):2850-62. Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN, Komisopoulou E, Henkin AH, Soto H, Chamberlain BT, Vergnes L, Jung ME, Torres JZ, Liau LM, Christofk HR, Prins RM, Mischel PS, Reue K, Graeber TG, Bensinger SJ. PMID: 23440422; PMCID: PMC3919498.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    112. X and Y chromosome complement influence adiposity and metabolism in mice. Endocrinology. 2013 Mar; 154(3):1092-104. Chen X, McClusky R, Itoh Y, Reue K, Arnold AP. PMID: 23397033; PMCID: PMC3578992.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    113. Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization. J Lipid Res. 2012 Dec; 53(12):2610-9. Chao LC, Wroblewski K, Ilkayeva OR, Stevens RD, Bain J, Meyer GA, Schenk S, Martinez L, Vergnes L, Narkar VA, Drew BG, Hong C, Boyadjian R, Hevener AL, Evans RM, Reue K, Spencer MJ, Newgard CB, Tontonoz P. PMID: 23028113; PMCID: PMC3494265.
      View in: PubMed   Mentions: 40     Fields:    Translation:AnimalsCells
    114. Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2541-6. Zhang L, Reue K, Fong LG, Young SG, Tontonoz P. PMID: 22936343; PMCID: PMC4280256.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    115. Mouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellum. Proc Natl Acad Sci U S A. 2012 Sep 11; 109(37):E2486-95. Dwyer JR, Donkor J, Zhang P, Csaki LS, Vergnes L, Lee JM, Dewald J, Brindley DN, Atti E, Tetradis S, Yoshinaga Y, De Jong PJ, Fong LG, Young SG, Reue K. PMID: 22908270; PMCID: PMC3443145.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    116. Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome. 2012 Oct; 23(9-10):680-92. Ghazalpour A, Rau CD, Farber CR, Bennett BJ, Orozco LD, van Nas A, Pan C, Allayee H, Beaven SW, Civelek M, Davis RC, Drake TA, Friedman RA, Furlotte N, Hui ST, Jentsch JD, Kostem E, Kang HM, Kang EY, Joo JW, Korshunov VA, Laughlin RE, Martin LJ, Ohmen JD, Parks BW, Pellegrini M, Reue K, Smith DJ, Tetradis S, Wang J, Wang Y, Weiss JN, Kirchgessner T, Gargalovic PS, Eskin E, Lusis AJ, LeBoeuf RC. PMID: 22892838; PMCID: PMC3586763.
      View in: PubMed   Mentions: 90     Fields:    Translation:Animals
    117. ABCC6 localizes to the mitochondria-associated membrane. Circ Res. 2012 Aug 17; 111(5):516-20. Martin LJ, Lau E, Singh H, Vergnes L, Tarling EJ, Mehrabian M, Mungrue I, Xiao S, Shih D, Castellani L, Ping P, Reue K, Stefani E, Drake TA, Bostrom K, Lusis AJ. PMID: 22811557; PMCID: PMC3540978.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    118. Ulcerative dermatitis in C57BL/6 mice exhibits an oxidative stress response consistent with normal wound healing. Comp Med. 2012 Jun; 62(3):166-71. Williams LK, Csaki LS, Cantor RM, Reue K, Lawson GW. PMID: 22776048; PMCID: PMC3364703.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    119. The number of x chromosomes causes sex differences in adiposity in mice. PLoS Genet. 2012; 8(5):e1002709. Chen X, McClusky R, Chen J, Beaven SW, Tontonoz P, Arnold AP, Reue K. PMID: 22589744; PMCID: PMC3349739.
      View in: PubMed   Mentions: 162     Fields:    Translation:AnimalsCells
    120. Reciprocal metabolic perturbations in the adipose tissue and liver of GPIHBP1-deficient mice. Arterioscler Thromb Vasc Biol. 2012 Feb; 32(2):230-5. Weinstein MM, Goulbourne CN, Davies BS, Tu Y, Barnes RH, Watkins SM, Davis R, Reue K, Tontonoz P, Beigneux AP, Fong LG, Young SG. PMID: 22173228; PMCID: PMC3281771.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    121. Lipin-1 phosphatidic phosphatase activity modulates phosphatidate levels to promote peroxisome proliferator-activated receptor γ (PPARγ) gene expression during adipogenesis. J Biol Chem. 2012 Jan 27; 287(5):3485-94. Zhang P, Takeuchi K, Csaki LS, Reue K. PMID: 22157014; PMCID: PMC3271002.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    122. Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem. 2012 Jan 27; 287(5):3123-37. Han S, Bahmanyar S, Zhang P, Grishin N, Oegema K, Crooke R, Graham M, Reue K, Dixon JE, Goodman JM. PMID: 22134922; PMCID: PMC3283218.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansAnimalsCells
    123. UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J. 2011 Nov 15; 30(24):4860-73. Zhang J, Khvorostov I, Hong JS, Oktay Y, Vergnes L, Nuebel E, Wahjudi PN, Setoguchi K, Wang G, Do A, Jung HJ, McCaffery JM, Kurland IJ, Reue K, Lee WN, Koehler CM, Teitell MA. PMID: 22085932; PMCID: PMC3243621.
      View in: PubMed   Mentions: 254     Fields:    Translation:HumansCells
    124. Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec; 22(23):4683-93. Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG. PMID: 21976703; PMCID: PMC3226484.
      View in: PubMed   Mentions: 131     Fields:    Translation:AnimalsCells
    125. A thematic review series: lipid droplet storage and metabolism: from yeast to man. J Lipid Res. 2011 Nov; 52(11):1865-8. Reue K. PMID: 21921134; PMCID: PMC3196222.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    126. Metabolic state of glioma stem cells and nontumorigenic cells. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):16062-7. Vlashi E, Lagadec C, Vergnes L, Matsutani T, Masui K, Poulou M, Popescu R, Della Donna L, Evers P, Dekmezian C, Reue K, Christofk H, Mischel PS, Pajonk F. PMID: 21900605; PMCID: PMC3179043.
      View in: PubMed   Mentions: 284     Fields:    Translation:HumansCells
    127. GPIHBP1, an endothelial cell transporter for lipoprotein lipase. J Lipid Res. 2011 Nov; 52(11):1869-84. Young SG, Davies BS, Voss CV, Gin P, Weinstein MM, Tontonoz P, Reue K, Bensadoun A, Fong LG, Beigneux AP. PMID: 21844202; PMCID: PMC3196223.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    128. Heart-type fatty acid-binding protein is essential for efficient brown adipose tissue fatty acid oxidation and cold tolerance. J Biol Chem. 2011 Jan 07; 286(1):380-90. Vergnes L, Chin R, Young SG, Reue K. PMID: 21044951; PMCID: PMC3012996.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    129. NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arterioscler Thromb Vasc Biol. 2011 Jan; 31(1):58-66. Barajas B, Che N, Yin F, Rowshanrad A, Orozco LD, Gong KW, Wang X, Castellani LW, Reue K, Lusis AJ, Araujo JA. PMID: 20947826; PMCID: PMC3037185.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    130. Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxid Redox Signal. 2011 Feb 01; 14(3):341-51. Devarajan A, Bourquard N, Hama S, Navab M, Grijalva VR, Morvardi S, Clarke CF, Vergnes L, Reue K, Teiber JF, Reddy ST. PMID: 20578959; PMCID: PMC3011913.
      View in: PubMed   Mentions: 94     Fields:    Translation:HumansAnimalsCells
    131. Cholesterol intake modulates plasma triglyceride levels in glycosylphosphatidylinositol HDL-binding protein 1-deficient mice. Arterioscler Thromb Vasc Biol. 2010 Nov; 30(11):2106-13. Weinstein MM, Tu Y, Beigneux AP, Davies BS, Gin P, Voss C, Walzem RL, Reue K, Tontonoz P, Bensadoun A, Fong LG, Young SG. PMID: 20814015; PMCID: PMC2959134.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    132. Lipins: multifunctional lipid metabolism proteins. Annu Rev Nutr. 2010 Aug 21; 30:257-72. Csaki LS, Reue K. PMID: 20645851; PMCID: PMC3738581.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimals
    133. Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes. J Biol Chem. 2010 Feb 05; 285(6):3857-3864. Péterfy M, Harris TE, Fujita N, Reue K. PMID: 19955570; PMCID: PMC2823528.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    134. Insulin resistance and altered systemic glucose metabolism in mice lacking Nur77. Diabetes. 2009 Dec; 58(12):2788-96. Chao LC, Wroblewski K, Zhang Z, Pei L, Vergnes L, Ilkayeva OR, Ding SY, Reue K, Watt MJ, Newgard CB, Pilch PF, Hevener AL, Tontonoz P. PMID: 19741162; PMCID: PMC2780886.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCells
    135. A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2. J Biol Chem. 2009 Oct 23; 284(43):29968-78. Donkor J, Zhang P, Wong S, O'Loughlin L, Dewald J, Kok BP, Brindley DN, Reue K. PMID: 19717560; PMCID: PMC2785625.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    136. Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. Cell Metab. 2009 Jun; 9(6):525-36. Dean JT, Tran L, Beaven S, Tontonoz P, Reue K, Dipple KM, Liao JC. PMID: 19490907; PMCID: PMC4277884.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    137. The lipin family: mutations and metabolism. Curr Opin Lipidol. 2009 Jun; 20(3):165-70. Reue K. PMID: 19369868; PMCID: PMC2875192.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimals
    138. Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis. Am J Physiol Endocrinol Metab. 2009 Jun; 296(6):E1195-209. Takeuchi K, Reue K. PMID: 19336658; PMCID: PMC2692402.
      View in: PubMed   Mentions: 195     Fields:    Translation:HumansAnimalsCells
    139. Phosphatidate degradation: phosphatidate phosphatases (lipins) and lipid phosphate phosphatases. Biochim Biophys Acta. 2009 Sep; 1791(9):956-61. Brindley DN, Pilquil C, Sariahmetoglu M, Reue K. PMID: 19250975; PMCID: PMC2875194.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    140. Hoofbeats, zebras, and insights into insulin resistance. J Clin Invest. 2009 Feb; 119(2):249-51. Hegele RA, Reue K. PMID: 19244606; PMCID: PMC2631308.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    141. Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models. Hum Mol Genet. 2009 Mar 15; 18(6):1006-16. Phan J, Hickey MA, Zhang P, Chesselet MF, Reue K. PMID: 19124532; PMCID: PMC2649017.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    142. Metabolic syndrome: from epidemiology to systems biology. Nat Rev Genet. 2008 Nov; 9(11):819-30. Lusis AJ, Attie AD, Reue K. PMID: 18852695; PMCID: PMC2829312.
      View in: PubMed   Mentions: 153     Fields:    Translation:Humans
    143. Lipin proteins and metabolic homeostasis. J Lipid Res. 2009 Apr; 50 Suppl:S109-14. Reue K, Dwyer JR. PMID: 18941140; PMCID: PMC2674718.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansAnimals
    144. Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism. J Lipid Res. 2008 Dec; 49(12):2493-503. Reue K, Brindley DN. PMID: 18791037; PMCID: PMC2582367.
      View in: PubMed   Mentions: 104     Fields:    Translation:HumansAnimals
    145. The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL. J Lipid Res. 2009 Jan; 50(1):47-58. Bou Khalil M, Sundaram M, Zhang HY, Links PH, Raven JF, Manmontri B, Sariahmetoglu M, Tran K, Reue K, Brindley DN, Yao Z. PMID: 18769019.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansAnimals
    146. Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis. J Lipid Res. 2008 Jul; 49(7):1519-28. Zhang P, O'Loughlin L, Brindley DN, Reue K. PMID: 18362392; PMCID: PMC2431106.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    147. Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically. J Lipid Res. 2008 May; 49(5):1056-67. Manmontri B, Sariahmetoglu M, Donkor J, Bou Khalil M, Sundaram M, Yao Z, Reue K, Lehner R, Brindley DN. PMID: 18245816; PMCID: PMC2311443.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    148. Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice. J Lipid Res. 2008 Apr; 49(4):823-31. Nagle CA, Vergnes L, Dejong H, Wang S, Lewin TM, Reue K, Coleman RA. PMID: 18192653; PMCID: PMC2819352.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    149. Genetic factors in type 2 diabetes: all in the (lipin) family. Diabetes. 2007 Dec; 56(12):2842-3. Reue K, Donkor J. PMID: 18042760.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    150. The lipin protein family: dual roles in lipid biosynthesis and gene expression. FEBS Lett. 2008 Jan 09; 582(1):90-6. Reue K, Zhang P. PMID: 18023282; PMCID: PMC2848953.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    151. Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia. Nat Genet. 2007 Dec; 39(12):1483-7. Péterfy M, Ben-Zeev O, Mao HZ, Weissglas-Volkov D, Aouizerat BE, Pullinger CR, Frost PH, Kane JP, Malloy MJ, Reue K, Pajukanta P, Doolittle MH. PMID: 17994020.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimalsCells
    152. Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men. J Clin Endocrinol Metab. 2008 Jan; 93(1):233-9. Donkor J, Sparks LM, Xie H, Smith SR, Reue K. PMID: 17925338; PMCID: PMC2190746.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimals
    153. Cell nuclei spin in the absence of lamin b1. J Biol Chem. 2007 Jul 06; 282(27):20015-26. Ji JY, Lee RT, Vergnes L, Fong LG, Stewart CL, Reue K, Young SG, Zhang Q, Shanahan CM, Lammerding J. PMID: 17488709.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    154. The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARgamma expression. Cell Metab. 2007 May; 5(5):357-70. Waki H, Park KW, Mitro N, Pei L, Damoiseaux R, Wilpitz DC, Reue K, Saez E, Tontonoz P. PMID: 17488638.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansAnimalsCells
    155. The role of lipin 1 in adipogenesis and lipid metabolism. Novartis Found Symp. 2007; 286:58-68; discussion 68-71, 162-3, 196-203. Reue K. PMID: 18269174.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    156. Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns. J Biol Chem. 2007 Feb 09; 282(6):3450-7. Donkor J, Sariahmetoglu M, Dewald J, Brindley DN, Reue K. PMID: 17158099.
      View in: PubMed   Mentions: 201     Fields:    Translation:HumansAnimalsCells
    157. Lipin deficiency impairs diurnal metabolic fuel switching. Diabetes. 2006 Dec; 55(12):3429-38. Xu J, Lee WN, Phan J, Saad MF, Reue K, Kurland IJ. PMID: 17130489.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    158. Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor gamma activation. Diabetes. 2006 Oct; 55(10):2811-8. Yao-Borengasser A, Rasouli N, Varma V, Miles LM, Phanavanh B, Starks TN, Phan J, Spencer HJ, McGehee RE, Reue K, Kern PA. PMID: 17003347.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    159. Approaches to lipid metabolism gene identification and characterization in the postgenomic era. J Lipid Res. 2006 Sep; 47(9):1891-907. Reue K, Vergnes L. PMID: 16835441.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    160. Lamins A and C but not lamin B1 regulate nuclear mechanics. J Biol Chem. 2006 Sep 01; 281(35):25768-80. Lammerding J, Fong LG, Ji JY, Reue K, Stewart CL, Young SG, Lee RT. PMID: 16825190.
      View in: PubMed   Mentions: 336     Fields:    Translation:AnimalsCells
    161. Metabolic consequences of lipodystrophy in mouse models. Curr Opin Clin Nutr Metab Care. 2006 Jul; 9(4):436-41. Reue K, Phan J. PMID: 16778573.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    162. Agpat6--a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium. J Lipid Res. 2006 Apr; 47(4):734-44. Beigneux AP, Vergnes L, Qiao X, Quatela S, Davis R, Watkins SM, Coleman RA, Walzem RL, Philips M, Reue K, Young SG. PMID: 16449762; PMCID: PMC3196597.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansAnimalsCells
    163. Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity. J Lipid Res. 2006 Apr; 47(4):745-54. Vergnes L, Beigneux AP, Davis R, Watkins SM, Young SG, Reue K. PMID: 16436371; PMCID: PMC2901549.
      View in: PubMed   Mentions: 64     Fields:    Translation:Animals
    164. Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism. Hum Mol Genet. 2006 Feb 01; 15(3):377-86. Suviolahti E, Reue K, Cantor RM, Phan J, Gentile M, Naukkarinen J, Soro-Paavonen A, Oksanen L, Kaprio J, Rissanen A, Salomaa V, Kontula K, Taskinen MR, Pajukanta P, Peltonen L. PMID: 16357106.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimals
    165. Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis. J Biol Chem. 2005 Sep 23; 280(38):32883-9. Péterfy M, Phan J, Reue K. PMID: 16049017.
      View in: PubMed   Mentions: 114     Fields:    Translation:AnimalsCells
    166. Lipin, a lipodystrophy and obesity gene. Cell Metab. 2005 Jan; 1(1):73-83. Phan J, Reue K. PMID: 16054046.
      View in: PubMed   Mentions: 144     Fields:    Translation:AnimalsCells
    167. Biphasic expression of lipin suggests dual roles in adipocyte development. Drug News Perspect. 2005 Jan-Feb; 18(1):5-11. Phan J, Peterfy M, Reue K. PMID: 15753971.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    168. Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice. Proc Natl Acad Sci U S A. 2004 Dec 28; 101(52):18111-6. Fong LG, Ng JK, Meta M, Coté N, Yang SH, Stewart CL, Sullivan T, Burghardt A, Majumdar S, Reue K, Bergo MO, Young SG. PMID: 15608054; PMCID: PMC536056.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    169. Lamin B1 is required for mouse development and nuclear integrity. Proc Natl Acad Sci U S A. 2004 Jul 13; 101(28):10428-33. Vergnes L, Péterfy M, Bergo MO, Young SG, Reue K. PMID: 15232008; PMCID: PMC478588.
      View in: PubMed   Mentions: 196     Fields:    Translation:AnimalsCells
    170. Lipin expression preceding peroxisome proliferator-activated receptor-gamma is critical for adipogenesis in vivo and in vitro. J Biol Chem. 2004 Jul 09; 279(28):29558-64. Phan J, Péterfy M, Reue K. PMID: 15123608.
      View in: PubMed   Mentions: 100     Fields:    Translation:AnimalsCells
    171. Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression. J Biol Chem. 2003 Oct 31; 278(44):42774-84. Vergnes L, Phan J, Strauss M, Tafuri S, Reue K. PMID: 12923166.
      View in: PubMed   Mentions: 68     Fields:    Translation:AnimalsCells
    172. A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13. J Lipid Res. 2003 Mar; 44(3):503-11. Vergnes L, Phan J, Stolz A, Reue K. PMID: 12562828.
      View in: PubMed   Mentions: 21     Fields:    Translation:AnimalsCells
    173. Mouse models of lipodystrophy. Curr Atheroscler Rep. 2000 Sep; 2(5):390-6. Reue K, Péterfy M. PMID: 11122770.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    174. Evidence for hormone-sensitive lipase mRNA expression in human monocyte/macrophages. Arterioscler Thromb Vasc Biol. 1997 Dec; 17(12):3428-32. Reue K, Cohen RD, Schotz MC. PMID: 9437189.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    With one click, see people who:

    Run Clinical Trials

    See more options in the Advanced Search tab

    Karen's Networks
    Concepts (670)
    Derived automatically from this person's publications.
    Explore
    _
    Co-Authors (143)
    People in Profiles who have published with this person.
    Explore
    _
    Similar People (60)
    People who share similar concepts with this person.
    Explore
    _
    Same Department
    Search Department
    _

    UCLA Profiles is managed by the UCSF Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number UL1 TR000004) at the National Institutes of Health (NIH).
    This site is running Profiles RNS version UCSF-v3.1.0-3-g1ef1264b on PROFILES-PWEB03. We use cookies to operate our website. We also use cookies to analyze our site’s performance and improve your experience on our site. For more information about how we use cookies, please see our Website Terms of Use.

    Copyright © The Regents of the University of California