Eli K Ipp, M.D., M.B.

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A Short Biography:

Dr. Ipp is Professor of Medicine and Head of the Section of Diabetes and Metabolism. His primary research interest has been the physiology of hormone secretion in the islets of Langerhans. Current goals of the lab are studies of early beta cell dysfunction. One focus of this effort is work at a basic and clinical level on oscillatory phenomena involved in the secretion of insulin and the regulation of carbohydrate metabolism. Another is the study of islet dysfunction in subjects at-risk for type 2 diabetes mellitus and applying genetic approaches to identify these individuals. This includes clinical studies in which families and sib pairs with type 2 diabetes are collected. Also patients representing unique clinical subtypes of type 2 diabetes are phenotyped in detail and candidate genes explored. Possible genetic and phenotypic overlap between type 1 and type 2 diabetes is also being evaluated. Other clinical studies include the development of improved methods for the evaluation of insulinomas and other hypoglycemic disorders.
Work Titles
CTSI Co-Leader, Clinical Immunology Research Laboratory (CIRL) Member, CTSI
The Lundquist Institute for Biomedical Innovation Professor, ENDOCRINOLOGY, METABOLISM & NUTRITION
UCLA Professor, Medicine
Education:
Degrees:
M.B., University of the Witwatersrand Medical School, 1968
M.D.
Internship:
1968 - 1969 Baragwanath Hospital, Johannesburg
Residency:
1970 - 1974 Tel Hashomer Hospital and Tel Aviv University Medical School, Israel

Contact Information:

Email Address:

ipp@gcrc.humc.edu

Work Email Address:

ipp@lundquist.org


Website:

Web-Profile

Fax Number:

(310) 533-6972

Work Phone Number:

(310) 222-2503

(310) 533-3681

Mailing Address:

1000 West Carson Street
mailbox 16
Torrance, CA 90502


Publications:

A selected list of publications:

Sheu Wayne H-H, Kuo Jane Z, Lee I-Te, Hung Yi-Jen, Lee Wen-Jane, Tsai Hin-Yeung, Wang J-S, Goodarzi Mark O, Klein Ronald, Klein Barbara E K, Ipp Eli, Lin Shin-Yi, Guo Xiuqing, Hsieh Chang-Hsun, Taylor Kent D, Fu Chia-Po, Rotter Jerome I, Chen Yii-Der I   Genome-wide association study in a Chinese population with diabetic retinopathy Human molecular genetics, 2013; .
Chlebowski Rowan T, McTiernan Anne, Wactawski-Wende Jean, Manson JoAnn E, Aragaki Aaron K, Rohan Thomas, Ipp Eli, Kaklamani Virginia G, Vitolins Mara, Wallace Robert, Gunter Marc, Phillips Lawrence S, Strickler Howard, Margolis Karen, Euhus David M   Diabetes, metformin, and breast cancer in postmenopausal women Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012; 30(23): 2844-52.
Patterson Mary E, Mao Catherine S, Yeh Michael W, Ipp Eli, Cortina Galen, Barank David, Vasinrapee Panukorn, Pawlikowska-Haddal Anna, Lee W N Paul, Yee Jennifer K   Hyperinsulinism presenting in childhood and treatment by conservative pancreatectomy Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2012; 18(3): e52-6.
Djekic Kristina, Mouzeyan Aram, Ipp Eli   Latent autoimmune diabetes of adults is phenotypically similar to type 1 diabetes in a minority population The Journal of clinical endocrinology and metabolism, 2012; 97(3): E409-13.
Kuo Jane Z, Guo Xiuqing, Klein Ronald, Klein Barbara E, Cui Jinrui, Rotter Jerome I, Ipp Eli, Chen Yii-Der Ida   Systemic soluble tumor necrosis factor receptors 1 and 2 are associated with severity of diabetic retinopathy in Hispanics Ophthalmology, 2012; 119(5): 1041-6.
Kim Sulgi, Abboud Hanna E, Pahl Madeleine V, Tayek John, Snyder Susan, Tamkin James, Alcorn Harry, Ipp Eli, Nast Cynthia C, Elston Robert C, Iyengar Sudha K, Adler Sharon G   Examination of association with candidate genes for diabetic nephropathy in a Mexican American population Clinical journal of the American Society of Nephrology : CJASN, 2010; 5(6): 1072-8.
Adler Sharon, Pahl Madeleine, Abboud Hanna, Nicholas Susanne, Ipp Eli, Seldin Michael   Mexican-American admixture mapping analyses for diabetic nephropathy in type 2 diabetes mellitus Seminars in nephrology, 2010; 30(2): 141-9.
Charfen Michelle A, Ipp Eli, Kaji Amy H, Saleh Tawny, Qazi Mohammed F, Lewis Roger J   Detection of undiagnosed diabetes and prediabetic states in high-risk emergency department patients Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009; 16(5): 394-402.
Pettitt David J, Okada Wollitzer Alison, Jovanovic Lois, He Guozhong, Ipp Eli   Decreasing the risk of diabetic retinopathy in a study of case management: the California Medi-Cal Type 2 Diabetes Study Diabetes care, 2005; 28(12): 2819-22.
Ipp Eli, Aquino Roxanne Lucas, Christenson Peter   Point: Self-monitoring of blood glucose in type 2 diabetic patients not receiving insulin: the sanguine approach Diabetes care, 2005; 28(6): 1528-30.
Mehrotra Rajnish, Budoff Matthew, Hokanson John E, Ipp Eli, Takasu Junichiro, Adler Sharon   Progression of coronary artery calcification in diabetics with and without chronic kidney disease Kidney international, 2005; 68(3): 1258-66.
Mehrotra Rajnish, Westenfeld Ralf, Christenson Peter, Budoff Matthew, Ipp Eli, Takasu Junichiro, Gupta Ajay, Norris Keith, Ketteler Markus, Adler Sharon   Serum fetuin-A in nondialyzed patients with diabetic nephropathy: relationship with coronary artery calcification Kidney international, 2005; 67(3): 1070-7.
Mehrotra Rajnish, Budoff Matthew, Christenson Peter, Ipp Eli, Takasu Junichiro, Gupta Ajay, Norris Keith, Adler Sharon   Determinants of coronary artery calcification in diabetics with and without nephropathy Kidney international, 2004; 66(5): 2022-31.
Mao Catherine S, Berman Nancy, Ipp Eli   Loss of entrainment of high-frequency plasma insulin oscillations in type 2 diabetes is likely a glucose-specific beta-cell defect American journal of physiology. Endocrinology and metabolism, 2004; 287(1): E50-4.
Genter P, Berman N, Jacob M, Ipp E   Counterregulatory hormones oscillate during steady-state hypoglycemia The American journal of physiology, 1998; 275(5 Pt 1): E821-9.
Mao C S, Riegelhuth M E, Van Gundy D, Cortez C, Melendez S, Ipp E   An overnight insulin infusion algorithm provides morning normoglycemia and can be used to predict insulin requirements in noninsulin-dependent diabetes mellitus The Journal of clinical endocrinology and metabolism, 1997; 82(8): 2466-70.
Berman N, Genter P, Chou H F, Cortez C, Bowsher R, Ipp E   Erratic oscillatory characteristics of plasma insulin concentrations in patients with insulinoma: mechanism for unpredictable hypoglycemia The Journal of clinical endocrinology and metabolism, 1997; 82(9): 2899-903.
Marsoobian V, Grosvenor M, Jacob M, Ipp E   Very-low-energy diets alter the counterregulatory response to falling plasma glucose concentrations The American journal of clinical nutrition, 1995; 61(2): 373-8.
Genter P M, Ipp E   Accuracy of plasma glucose measurements in the hypoglycemic range Diabetes care, 1994; 17(6): 595-8.
Genter P, Ipp E   Plasma glucose thresholds for counterregulation after an oral glucose load Metabolism: clinical and experimental, 1994; 43(1): 98-103.

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