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Mirella Dapretto, Ph.D.
Contact Information:
Work Phone Number:
310-206-2960
Laboratory Address:
Laboratory Ahmanson-Lovelace Brain Mapping Center Los Angeles, CA 90095 UNITED STATES
Office Address:
Office Ahmanson-Lovelace Brain Mapping Center 660 Charles E. Young Drive South Los Angeles, CA 90095 UNITED STATES
Professor,
Psychiatry and Biobehavioral Sciences
Center for Autism Research and Treatment (CART)
Semel Institute for Neuroscience and Human Behavior
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Member,
Brain Research Institute
Neuroscience GPB Home Area
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Detailed Biography:
Dr. Dapretto is presently appointed as Professor in the Department of Psychiatry and Biobehavioral Sciences at UCLA. She received a Ph.D. in Developmental Psychology from the UCLA Psychology Department, specializing in language development. As a postdoctoral fellow at the UCLA Ahmanson-Lovelace Brain Mapping Center, she later acquired expertise in functional magnetic resonance imaging (fMRI) under the mentorship of Dr. Susan Bookheimer. Dr. Dapretto has been the recipient of several awards, including NIH fundings to study the neural systems associated with language functions in typically developing children, and several grants (funded by the Cure Autism Now foundation, the M.I.N.D. Research Institute at UC Davis, the National Alliance for Autism Research, and Autism Speaks) to study the neural basis of the socio-communicative impairments observed in autism. As part of the UCLA Autism Center of Excellence (ACE) funded by NIH, Dr. Dapretto currently serves as the PI of the imaging project (Project 4), as well as Co-PI of a project in infants at ultra high-risk for autism (Project 1 ). In addition, Dr. Dapretto is also a co-investigator on several large-scale collaborative studies headed by Drs. Bookheimer, Geschwind, and Wang, including a recently funded multi-site ACE Network (PI: Pelphrey; participating sites: Yale, UCLA, Harvard, University of Washington).
Capitalizing on her dual training as a developmental psychologist and a neuroscientist, Dr. Dapretto’s research combines neuroimaging, behavioral, and genetic data to better characterize typical and atypical brain function from infancy to adulthood. Her work has been published in prestigious scientific journals such as Neuron, Nature Neuroscience, Biological Psychiatry, Brain, and Archives of General Psychiatry.
Publications:
Scott-Van Zeeland Ashley A, Abrahams Brett S, Alvarez-Retuerto Ana I, Sonnenblick Lisa I, Rudie Jeffrey D, Ghahremani Dara, Mumford Jeanette A, Poldrack Russell A, Dapretto Mirella, Geschwind Daniel H, Bookheimer Susan Y
Altered functional connectivity in frontal lobe circuits is associated
with variation in the autism risk gene CNTNAP2
Science translational medicine,
2010; 2(56):
56ra80.
Scott-Van Zeeland Ashley A, Dapretto Mirella, Ghahremani Dara G, Poldrack Russell A, Bookheimer Susan Y
Reward processing in autism
Autism research : official journal of the International Society for Autism Research,
2010; 3(2):
53-67.
Lu Lisa H, Dapretto Mirella, O'Hare Elizabeth D, Kan Eric, McCourt Sarah T, Thompson Paul M, Toga Arthur W, Bookheimer Susan Y, Sowell Elizabeth R
Relationships between brain activation and brain structure in normally
developing children
Cerebral cortex (New York, N.Y. : 1991),
2009; 19(11):
2595-604.
Rudie Jeffrey D, Hernandez Leanna M, Brown Jesse A, Beck-Pancer Devora, Colich Natalie L, Gorrindo Philip, Thompson Paul M, Geschwind Daniel H, Bookheimer Susan Y, Levitt Pat, Dapretto Mirella
Autism-associated promoter variant in MET impacts functional and
structural brain networks
Neuron,
2012; 75(5):
904-15.
Dennis Emily L, Jahanshad Neda, Rudie Jeffrey D, Brown Jesse A, Johnson Kori, McMahon Katie L, de Zubicaray Greig I, Montgomery Grant, Martin Nicholas G, Wright Margaret J, Bookheimer Susan Y, Dapretto Mirella, Toga Arthur W, Thompson Paul M
Altered structural brain connectivity in healthy carriers of the
autism risk gene, CNTNAP2
Brain connectivity,
2011; 1(6):
447-59.
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