Jerome Zack, Ph.D.

A Short Biography:

Dr. Jerome Zack is a Professor in the Department of Medicine and Professor and Chair of the Department of Microbiology, Immunology & Molecular Genetics at the David Geffen School of Medicine at UCLA. He joined the UCLA faculty in 1991, and teaches the undergraduate immunology course. The author of more than 150 scientific publications, Dr. Zack is best known for his innovative work on how HIV replicates and causes disease, and in developing new therapeutic approaches for eradicating the AIDS virus.

Work Titles
UCLA Director, Ahmanson Biological Imaging Division Director, Center For Aids Research Professor, Medicine Associate Director, Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research Associate Director, UCLA AIDS Institute Professor, Microbiology, Immunology & Molecular Genetics
Education:
Degrees:
Ph.D., University of Texas Health Science Center, 1980 - 1987
M.S., California State University, Long Beach, 1976 - 1980
B.S., University of California, Irvine, 1972 - 1976
Academic Experience:
1987 - 1989 UCLA School of Medicine, Los Angeles, Virology

Contact Information:

Work Email Address:

jzack@ucla.edu


Website:

Web-Profile

Fax Number:

310-825-6192

Work Phone Number:

310-825-0876

Work Address:

UCLA Med-Hemat & Onc/MIMG
615 Charles E. Young Drive South
BOX 957363, 190A BSRB
Los Angeles, CA 90095


Publications:

Zack Jerome A, Kim Sohn G, Vatakis Dimitrios N   HIV restriction in quiescent CD4⁺ T cells Retrovirology, 2013; 10(5): 37.
Liu Su-Yang, Aliyari Roghiyh, Chikere Kelechi, Li Guangming, Marsden Matthew D, Smith Jennifer K, Pernet Olivier, Guo Haitao, Nusbaum Rebecca, Zack Jerome A, Freiberg Alexander N, Su Lishan, Lee Benhur, Cheng Genhong   Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol Immunity, 2013; 38(1): 92-105.
Vatakis Dimitrios N, Arumugam Balamurugan, Kim Sohn G, Bristol Gregory, Yang Otto, Zack Jerome A   Introduction of exogenous T-cell receptors into human hematopoietic progenitors results in exclusion of endogenous T-cell receptor expression Molecular therapy : the journal of the American Society of Gene Therapy, 2013; 21(5): 1055-63.
DeChristopher Brian A, Loy Brian A, Marsden Matthew D, Schrier Adam J, Zack Jerome A, Wender Paul A   Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro Nature chemistry, 2012; 4(9): 705-10.
Karumbayaram Saravanan, Lee Peiyee, Azghadi Soheila F, Cooper Aaron R, Patterson Michaela, Kohn Donald B, Pyle April, Clark Amander, Byrne James, Zack Jerome A, Plath Kathrin, Lowry William E   From skin biopsy to neurons through a pluripotent intermediate under Good Manufacturing Practice protocols Stem cells translational medicine, 2012; 1(1): 36-43.
Marsden Matthew D, Kovochich Michael, Suree Nuttee, Shimizu Saki, Mehta Roshni, Cortado Ruth, Bristol Gregory, An Dong Sung, Zack Jerome A   HIV latency in the humanized BLT mouse Journal of virology, 2012; 86(1): 339-47.
Kitchen Scott G, Levin Bernard R, Bristol Gregory, Rezek Valerie, Kim Sohn, Aguilera-Sandoval Christian, Balamurugan Arumugam, Yang Otto O, Zack Jerome A   In vivo suppression of HIV by antigen specific T cells derived from engineered hematopoietic stem cells PLoS pathogens, 2012; 8(4): e1002649.
Vatakis Dimitrios N, Bristol Gregory C, Kim Sohn G, Levin Bernard, Liu Wei, Radu Caius G, Kitchen Scott G, Zack Jerome A   Using the BLT humanized mouse as a stem cell based gene therapy tumor model Journal of visualized experiments : JoVE, 2012; 38(70): e4181.
Marsden Matthew D, Krogstad Paul A, Zack Jerome A   Virological evidence supporting the use of raltegravir in HIV post-exposure prophylaxis regimens Antiviral therapy, 2012; 17(7): 1375-9.
Kovochich Michael, Marsden Matthew D, Zack Jerome A   Activation of latent HIV using drug-loaded nanoparticles PloS one, 2011; 6(4): e18270.
Vatakis Dimitrios N, Koya Richard C, Nixon Christopher C, Wei Liu, Kim Sohn G, Avancena Patricia, Bristol Gregory, Baltimore David, Kohn Donald B, Ribas Antoni, Radu Caius G, Galic Zoran, Zack Jerome A   Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells Proceedings of the National Academy of Sciences of the United States of America, 2011; 108(51): E1408-16.
Marban Céline, Su Trent, Ferrari Roberto, Li Bing, Vatakis Dimitrios, Pellegrini Matteo, Zack Jerome A, Rohr Olivier, Kurdistani Siavash K   Genome-wide binding map of the HIV-1 Tat protein to the human genome PloS one, 2011; 6(11): e26894.
Marsden Matthew D, Burke Bryan P, Zack Jerome A   HIV latency is influenced by regions of the viral genome outside of the long terminal repeats and regulatory genes Virology, 2011; 417(2): 394-9.
Mitsuyasu Ronald T, Zack Jerome A, Macpherson Janet L, Symonds Geoff P   Phase I/II Clinical Trials Using Gene-Modified Adult Hematopoietic Stem Cells for HIV: Lessons Learnt Stem cells international, 2011; 2011(11): 393698.
Marsden Matthew D, Avancena Patricia, Kitchen Christina M R, Hubbard Trish, Zack Jerome A   Single mutations in HIV integrase confer high-level resistance to raltegravir in primary human macrophages Antimicrobial agents and chemotherapy, 2011; 55(8): 3696-702.
Kitchen Scott G, Zack Jerome A   Stem cell-based approaches to treating HIV infection Current opinion in HIV and AIDS, 2011; 6(1): 68-73.
Shimizu Saki, Hong Patrick, Arumugam Balamurugan, Pokomo Lauren, Boyer Joshua, Koizumi Naoya, Kittipongdaja Panyamol, Chen Angela, Bristol Greg, Galic Zoran, Zack Jerome A, Yang Otto, Chen Irvin S Y, Lee Benhur, An Dong Sung   A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model Blood, 2010; 115(8): 1534-44.
Epeldegui Marta, Thapa Dharma R, De la Cruz Justin, Kitchen Scott, Zack Jerome A, Martínez-Maza Otoniel   CD40 ligand (CD154) incorporated into HIV virions induces activation-induced cytidine deaminase (AID) expression in human B lymphocytes PloS one, 2010; 5(7): e11448.
Sundaravaradan Vasudha, Mehta Roshni, Harris David T, Zack Jerome A, Ahmad Nafees   Differential expression and interaction of host factors augment HIV-1 gene expression in neonatal mononuclear cells Virology, 2010; 400(1): 32-43.
Marsden Matthew D, Zack Jerome A   Establishment and maintenance of HIV latency: model systems and opportunities for intervention Future virology, 2010; 5(1): 97-109.
Tchieu Jason, Kuoy Edward, Chin Mark H, Trinh Hung, Patterson Michaela, Sherman Sean P, Aimiuwu Otaren, Lindgren Anne, Hakimian Shahrad, Zack Jerome A, Clark Amander T, Pyle April D, Lowry William E, Plath Kathrin   Female human iPSCs retain an inactive X chromosome Cell stem cell, 2010; 7(3): 329-42.
Brown Helen J, Peng Li, Harada Josephine N, Walker John R, Cole Steven, Lin Su-Fang, Zack Jerome A, Chanda Sumit K, Sun Ren   Gene expression and transcription factor profiling reveal inhibition of transcription factor cAMP-response element-binding protein by gamma-herpesvirus replication and transcription activator The Journal of biological chemistry, 2010; 285(33): 25139-53.
Vatakis Dimitrios N, Nixon Christopher C, Zack Jerome A   Quiescent T cells and HIV: an unresolved relationship Immunologic research, 2010; 48(1-3): 110-21.
Conway Anne E, Lindgren Anne, Galic Zoran, Pyle April D, Wu Hong, Zack Jerome A, Pelligrini Matteo, Teitell Michael A, Clark Amander T   A self-renewal program controls the expansion of genetically unstable cancer stem cells in pluripotent stem cell-derived tumors Stem cells (Dayton, Ohio), 2009; 27(1): 18-28.
Bernstein Helene B, Wang Guangwu, Plasterer Mary C, Zack Jerome A, Ramasastry Parthasarathy, Mumenthaler Shannon M, Kitchen Christina M R   CD4+ NK cells can be productively infected with HIV, leading to downregulation of CD4 expression and changes in function Virology, 2009; 387(1): 59-66.
Vatakis Dimitrios N, Nixon Christopher C, Bristol Gregory, Zack Jerome A   Differentially stimulated CD4+ T cells display altered human immunodeficiency virus infection kinetics: implications for the efficacy of antiviral agents Journal of virology, 2009; 83(7): 3374-8.
Kitchen Scott G, Bennett Michael, Galić Zoran, Kim Joanne, Xu Qing, Young Alan, Lieberman Alexis, Joseph Aviva, Goldstein Harris, Ng Hwee, Yang Otto, Zack Jerome A   Engineering antigen-specific T cells from genetically modified human hematopoietic stem cells in immunodeficient mice PloS one, 2009; 4(12): e8208.
Marsden Matthew D, Zack Jerome A   Eradication of HIV: current challenges and new directions The Journal of antimicrobial chemotherapy, 2009; 63(1): 7-10.
Galić Zoran, Kitchen Scott G, Subramanian Aparna, Bristol Greg, Marsden Matthew D, Balamurugan Arumugam, Kacena Amelia, Yang Otto, Zack Jerome A   Generation of T lineage cells from human embryonic stem cells in a feeder free system Stem cells (Dayton, Ohio), 2009; 27(1): 100-7.
Vatakis Dimitrios N, Kim Sanggu, Kim Namshin, Chow Samson A, Zack Jerome A   Human immunodeficiency virus integration efficiency and site selection in quiescent CD4+ T cells Journal of virology, 2009; 83(12): 6222-33.
Subramanian Aparna, Guo Beichu, Marsden Matthew D, Galic Zoran, Kitchen Scott, Kacena Amelia, Brown Helen J, Cheng Genhong, Zack Jerome A   Macrophage differentiation from embryoid bodies derived from human embryonic stem cells Journal of stem cells, 2009; 4(1): 29-45.
Mitsuyasu Ronald T, Merigan Thomas C, Carr Andrew, Zack Jerome A, Winters Mark A, Workman Cassy, Bloch Mark, Lalezari Jacob, Becker Stephen, Thornton Lorna, Akil Bisher, Khanlou Homayoon, Finlayson Robert, McFarlane Robert, Smith Don E, Garsia Roger, Ma David, Law Matthew, Murray John M, von Kalle Christof, Ely Julie A, Patino Sharon M, Knop Alison E, Wong Philip, Todd Alison V, Haughton Margaret, Fuery Caroline, Macpherson Janet L, Symonds Geoff P, Evans Louise A, Pond Susan M, Cooper David A   Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells Nature medicine, 2009; 15(3): 285-92.
Miranda-Carboni Gustavo A, Krum Susan A, Yee Kathleen, Nava Miguel, Deng Qiming E, Pervin Shehla, Collado-Hidalgo Alicia, Galic Zoran, Zack Jerome A, Nakayama Keiko, Nakayama Keiichi I, Lane Timothy F   A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors Genes & development, 2008; 22(22): 3121-34.
Marsden Matthew D, Xu Jie, Hamer Dean, Zack Jerome A   Short communication: Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages AIDS research and human retroviruses, 2008; 24(11): 1399-404.
Burke B, Brown HJ, Marsden MD, Bristol G, Vatakis DN, Zack JA   A primary cell model for activation inducible human immunodeficiency virus, Journal of Virology, 2007; 81: : 7424-34.
Marsden Matthew D, Zack Jerome A   Human immunodeficiency virus bearing a disrupted central DNA flap is pathogenic in vivo Journal of virology, 2007; 81(11): 6146-50.
Vatakis Dimitrios N, Bristol Gregory, Wilkinson Thomas A, Chow Samson A, Zack Jerome A   Immediate activation fails to rescue efficient human immunodeficiency virus replication in quiescent CD4+ T cells Journal of virology, 2007; 81(7): 3574-82.
Hryniewicz Anna, Price David A, Moniuszko Marcin, Boasso Adriano, Edghill-Spano Yvette, West Sadie M, Venzon David, Vaccari Monica, Tsai Wen-Po, Tryniszewska Elzbieta, Nacsa Janos, Villinger Francois, Ansari Aftab A, Trindade Christopher J, Morre Michel, Brooks David, Arlen Philip, Brown Helen J, Kitchen Christina M R, Zack Jerome A, Douek Daniel C, Shearer Gene M, Lewis Mark G, Koup Richard A, Franchini Genoveffa   Interleukin-15 but not interleukin-7 abrogates vaccine-induced decrease in virus level in simian immunodeficiency virus mac251-infected macaques Journal of immunology (Baltimore, Md. : 1950), 2007; 178(6): 3492-504.
Burke Bryan, Brown Helen J, Marsden Matthew D, Bristol Gregory, Vatakis Dimitrios N, Zack Jerome A   Primary cell model for activation-inducible human immunodeficiency virus Journal of virology, 2007; 81(14): 7424-34.
Brown Helen J, Zack Jerome A   Animal models of HIV-1 latency and persistence Current opinion in HIV and AIDS, 2006; 1(2): 103-7.
Bernstein Helene B, Plasterer Mary C, Schiff Sherrie E, Kitchen Christina M R, Kitchen Scott, Zack Jerome A   CD4 expression on activated NK cells: ligation of CD4 induces cytokine expression and cell migration Journal of immunology (Baltimore, Md. : 1950), 2006; 177(6): 3669-76.
Groszer Matthias, Erickson Rebecca, Scripture-Adams Deirdre D, Dougherty Joseph D, Le Belle Janel, Zack Jerome A, Geschwind Daniel H, Liu Xin, Kornblum Harley I, Wu Hong   PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(1): 111-6.
Arlen Philip A, Brooks David G, Gao Lian Y, Vatakis Dimitrios, Brown Helen J, Zack Jerome A   Rapid expression of human immunodeficiency virus following activation of latently infected cells Journal of virology, 2006; 80(3): 1599-603.
Galic Zoran, Kitchen Scott G, Kacena Amelia, Subramanian Aparna, Burke Bryan, Cortado Ruth, Zack Jerome A   T lineage differentiation from human embryonic stem cells Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(31): 11742-7.
Cole Steve W, Yan Weihong, Galic Zoran, Arevalo Jesusa, Zack Jerome A   Expression-based monitoring of transcription factor activity: the TELiS database Bioinformatics (Oxford, England), 2005; 21(6): 803-10.
Brown Helen J, McBride William H, Zack Jerome A, Sun Ren   Prostratin and bortezomib are novel inducers of latent Kaposi's sarcoma-associated herpesvirus Antiviral therapy, 2005; 10(6): 745-51.
Brooks David G, Cohen Michael D, Jamieson Beth D, Poon Betty, Kitchen Scott G, Chow Samson A, Chen Irvin S Y, Zack Jerome A, Koka Prasad S   Rapid size dependent deletion of foreign gene sequences inserted into attenuated HIV-1 upon infection in vivo: implications for vaccine development Current HIV research, 2005; 3(4): 377-92.
Widney Daniel P, Breen Elizabeth C, Boscardin W John, Kitchen Scott G, Alcantar Juan M, Smith Jeffrey B, Zack Jerome A, Detels Roger, Martínez-Maza Otoniel   Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2005; 25(11): 702-6.
Kitchen Scott G, Whitmire Jason K, Jones Nicole R, Galic Zoran, Kitchen Christina M R, Ahmed Rafi, Zack Jerome A   The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens Proceedings of the National Academy of Sciences of the United States of America, 2005; 102(10): 3794-9.
Chang Margaret, Brown Helen J, Collado-Hidalgo Alicia, Arevalo Jesusa M, Galic Zoran, Symensma Tonia L, Tanaka Lena, Deng Hongyu, Zack Jerome A, Sun Ren, Cole Steve W   beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA Journal of virology, 2005; 79(21): 13538-47.
Chen Hongying, Zha Junli, Gowans Reginald E, Camargo Paulo, Nishitani Junko, McQuirter Joseph L, Cole Steve W, Zack Jerome A, Liu Xuan   Alcohol enhances HIV type 1 infection in normal human oral keratinocytes by up-regulating cell-surface CXCR4 coreceptor AIDS research and human retroviruses, 2004; 20(5): 513-9.
Amado Rafael G, Mitsuyasu Ronald T, Rosenblatt Joseph D, Ngok Frances K, Bakker Andreas, Cole Steve, Chorn Nathalie, Lin Lii-Shin, Bristol Gregory, Boyd Maureen P, MacPherson Janet L, Fanning Gregory C, Todd Alison V, Ely Julie A, Zack Jerome A, Symonds Geoff P   Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients Human gene therapy, 2004; 15(3): 251-62.
Kitchen Scott G, Jones Nicole R, LaForge Stuart, Whitmire Jason K, Vu Bien-Aimee, Galic Zoran, Brooks David G, Brown Stephen J, Kitchen Christina M R, Zack Jerome A   CD4 on CD8(+) T cells directly enhances effector function and is a target for HIV infection Proceedings of the National Academy of Sciences of the United States of America, 2004; 101(23): 8727-32.
Ali Ayub, Lubong Rachel, Ng Hwee, Brooks David G, Zack Jerome A, Yang Otto O   Impacts of epitope expression kinetics and class I downregulation on the antiviral activity of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes Journal of virology, 2004; 78(2): 561-7.
Burton Dennis R, Desrosiers Ronald C, Doms Robert W, Feinberg Mark B, Gallo Robert C, Hahn Beatrice, Hoxie James A, Hunter Eric, Korber Bette, Landay Alan, Lederman Michael M, Lieberman Judy, McCune Joseph M, Moore John P, Nathanson Neal, Picker Louis, Richman Douglas, Rinaldo Charles, Stevenson Mario, Watkins David I, Wolinsky Steven M, Zack Jerome A   Public health. A sound rationale needed for phase III HIV-1 vaccine trials Science (New York, N.Y.), 2004; 303(5656): 316.
Richlin Vanessa A, Arevalo Jesusa M G, Zack Jerome A, Cole Steve W   Stress-induced enhancement of NF-kappaB DNA-binding in the peripheral blood leukocyte pool: effects of lymphocyte redistribution Brain, behavior, and immunity, 2004; 18(3): 231-7.
Moore John P, Kitchen Scott G, Pugach Pavel, Zack Jerome A   The CCR5 and CXCR4 coreceptors--central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection AIDS research and human retroviruses, 2004; 20(1): 111-26.
Cole Steve W, Galic Zoran, Zack Jerome A   Controlling false-negative errors in microarray differential expression analysis: a PRIM approach Bioinformatics (Oxford, England), 2003; 19(14): 1808-16.
Koka Prasad S, Brooks David G, Razai Ali, Kitchen Christina M, Zack Jerome A   HIV type 1 infection alters cytokine mRNA expression in thymus AIDS research and human retroviruses, 2003; 19(1): 1-12.
Liu Xuan, Zha Junli, Nishitani Junko, Chen Hongying, Zack Jerome A   HIV-1 infection in peripheral blood lymphocytes (PBLs) exposed to alcohol Virology, 2003; 307(1): 37-44.
Liu Xuan, Zha Junli, Chen Hongying, Nishitani Junko, Camargo Paulo, Cole Steve W, Zack Jerome A   Human immunodeficiency virus type 1 infection and replication in normal human oral keratinocytes Journal of virology, 2003; 77(6): 3470-6.
Brooks David G, Arlen Philip A, Gao Lianying, Kitchen Christina M R, Zack Jerome A   Identification of T cell-signaling pathways that stimulate latent HIV in primary cells Proceedings of the National Academy of Sciences of the United States of America, 2003; 100(22): 12955-60.
Brooks David G, Hamer Dean H, Arlen Philip A, Gao Lianying, Bristol Greg, Kitchen Christina M R, Berger Edward A, Zack Jerome A   Molecular characterization, reactivation, and depletion of latent HIV Immunity, 2003; 19(3): 413-23.
Cole Steve W, Kemeny Margaret E, Fahey John L, Zack Jerome A, Naliboff Bruce D   Psychological risk factors for HIV pathogenesis: mediation by the autonomic nervous system Biological psychiatry, 2003; 54(12): 1444-56.
Kitchen Scott G, LaForge Stuart, Patel Viresh P, Kitchen Christina M, Miceli M Carrie, Zack Jerome A   Activation of CD8 T cells induces expression of CD4, which functions as a chemotactic receptor Blood, 2002; 99(1): 207-12.
Roth Michael D, Tashkin Donald P, Choi Ruth, Jamieson Beth D, Zack Jerome A, Baldwin Gayle Cocita   Cocaine enhances human immunodeficiency virus replication in a model of severe combined immunodeficient mice implanted with human peripheral blood leukocytes The Journal of infectious diseases, 2002; 185(5): 701-5.
Brooks David G, Zack Jerome A   Effect of latent human immunodeficiency virus infection on cell surface phenotype Journal of virology, 2002; 76(4): 1673-81.
Korin Yael D, Brooks David G, Brown Stephen, Korotzer Andrew, Zack Jerome A   Effects of prostratin on T-cell activation and human immunodeficiency virus latency Journal of virology, 2002; 76(16): 8118-23.
Scripture-Adams Deirdre D, Brooks David G, Korin Yael D, Zack Jerome A   Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype Journal of virology, 2002; 76(24): 13077-82.
Cole Alexander M, Hong Teresa, Boo Lee Ming, Nguyen Tung, Zhao Chengquan, Bristol Greg, Zack Jerome A, Waring Alan J, Yang Otto O, Lehrer Robert I   Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1 Proceedings of the National Academy of Sciences of the United States of America, 2002; 99(4): 1813-8.
Brooks DG, Kitchen SG, Kitchen CM, Scripture-Adams DD, Zack JA   Generation of HIV latency during thymopoiesis Nature medicine. , 2001; 7(4): 459-64.
Cole SW, Naliboff BD, Kemeny ME, Griswold MP, Fahey JL, Zack JA   Impaired response to HAART in HIV-infected individuals with high autonomic nervous system activity Proceedings of the National Academy of Sciences of the United States of America. , 2001; 98(22): 12695-700.
Kitchen SG, Killian S, Giorgi JV, Zack JA   Functional reconstitution of thymopoiesis after human immunodeficiency virus infection Journal of virology. , 2000; 74(6): 2943-8.
Jamieson BD, Douek DC, Killian S, Hultin LE, Scripture-Adams DD, Giorgi JV, Marelli D, Koup RA, Zack JA   Generation of functional thymocytes in the human adult Immunity. , 1999; 10(5): 569-75.
Koka PS, Fraser JK, Bryson Y, Bristol GC, Aldrovandi GM, Daar ES, Zack JA   Human immunodeficiency virus inhibits multilineage hematopoiesis in vivo Journal of virology. , 1998; 72(6): 5121-7.
Korin YD, Zack JA   Progression to the G1b phase of the cell cycle is required for completion of human immunodeficiency virus type 1 reverse transcription in T cells, J. Virol, 1998; 72: 3161-3168.
Aldrovandi GM, Gao L, Bristol G, Zack JA   Regions of human immunodeficiency virus type 1 nef required for function in vivo Journal of virology. , 1998; 72(9): 7032-9.
Kitchen SG, Uittenbogaart CH, Zack JA   Mechanism of HIV-1 localization in CD4-negative thymocytes: Differentiation from a CD4-positive precursor allows productive infection, J Virol, 1997; 71: 5713-5722.
Withers-Ward ES, Amado RG, Koka PS, Jamieson BD, Kaplan AH, Chen IS, Zack JA   Transient renewal of thymopoiesis in HIV-infected human thymic implants following antiviral therapy Nature medicine. , 1997; 3(10): 1102-9.
Akkina RK, Rosenblatt JD, Campbell AG, Chen ISY, Zack JA   Modeling human stem cell gene therapy in the SCID-hu mouse, Blood, 1994; 84: 1393-1398.
Aldrovandi GM, Feuer G, Gao L, Jamieson B, Kristeva M, Chen ISY, Zack JA   The SCID-hu mouse as a model for HIV-1 infection, Nature, 1993; 363: 732-736.

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