Judy Gasson, Ph.D.
Work Phone Number:
700 Tiverton Ave
Los Angeles, CA 90095
700 Tiverton Ave
Los Angeles, CA 90095
Senior Associate Dean for Research,
David Geffen School of Medicine at UCLA
Department of Medicine
Jonsson Comprehensive Cancer Center
Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research
A Short Biography:
Judith C. Gasson, a professor of biological chemistry and medicine, became director of UCLA?s Jonsson Comprehensive Cancer Center on Sept. 15, 1995. A molecular biologist, Gasson is responsible for one of only 39 institutions nationwide designated as comprehensive cancer centers by the National Cancer Institute.
In addition to her administrative duties, Gasson also is a gifted scientist. She was instrumental in purifying for the first time a hormone-like substance that increases the speed of bone marrow cell reproduction. That substance, called GM-CSF, is used to help prevent infections in cancer patients, and to allow patients to tolerate more chemotherapy and radiation than had previously been possible.
In 2005, Gasson was named a co-director of the UCLA Institute of Stem Cell Biology and Medicine and she recently testified before a key Senate subcommittee on the promise of stem cell research in cancer. Gasson also serves as a board member for the American Association for Cancer Research.
She earned a bachelor?s degree in microbiology from Colorado State University and a doctorate in physiology at the University of Colorado. Gasson did post doctoral work at the Salk Institute in La Jolla. In 1983, she left the Salk Institute to join UCLA's Jonsson Cancer Center, which comprises more than 240 researchers and clinicians engaged in research, prevention, detection, control, treatment and education.
One of the nation's largest comprehensive cancer centers, the Jonsson center is dedicated to promoting research and translating the results into leading-edge clinical studies. In July 2005, the Jonsson Cancer Center was named the best cancer center in the western United States by U.S. News & World Report, a ranking it has held for six consecutive years.
Molecular Physiology of Human Blood Cell Production
Judy Gasson is a professor of Medicine (Hem-Onc) and Biological Chemistry and the director of UCLA?s Jonsson Comprehensive Cancer Center. Her laboratory studies the molecular events that regulate proliferation and differentiation in mouse and human blood cell (hematopoietic) progenitor cells. When these processes become unregulated leukemias and other diseases can result. In the mid-1980s she and her collaborators purified the human Granulocyte-Macrophage Colony-Stimulating-Factor (GM-CSF) and defined many of its biological activities; it was subsequently used to treat patients recovering from bone marrow transplantation. Her current activities are focused upon in vitro model systems that are designed to better understand the interactions between blood cell progenitor cells and the stroma cells necessary for their proliferation and differentiation in the bone marrow.
Judith Gasson, Ph.D., became the director of UCLA's Jonsson Comprehensive Cancer Center (JCCC) on Sept. 15, 1995. She is a molecular biologist and is responsible for one of only 40 institutions designated as comprehensive cancer centers by the National Cancer Institute.
Gasson earned her doctorate degree in physiology at the University of Colorado in 1979. She did her postdoctoral work at the Salk Institute in La Jolla, CA, studying glucocorticoid hormones, which are made by the adrenal gland in response to stress. In 1983, she left the Salk Institute to join JCCC.
Gasson was instrumental in purifying for the first time a hormone-like substance that increases the speed of bone marrow cell reproduction. That substance, called GM-CSF, is used to help prevent infections in cancer patients and to allow those patients to tolerate more chemotherapy and radiation than had previously been possible.
For the past fifteen years, Dr. Gasson has been the director of UCLA?s Jonsson Comprehensive Cancer Center (JCCC), among the nation?s top 10, according to U.S. News & World Report. Under her leadership, the JCCC has become a recognized international pioneer in ?translating? laboratory discoveries into more effective new therapies for cancer patients everywhere.
Zovein Ann C, Hofmann Jennifer J, Lynch Maureen, French Wendy J, Turlo Kirsten A, Yang Yanan, Becker Michael S, Zanetta Lucia, Dejana Elisabetta, Gasson Judith C, Tallquist Michelle D, Iruela-Arispe M Luisa
Fate tracing reveals the endothelial origin of hematopoietic stem
Cell stem cell,
Rubin Ethel, Wu Xinyan, Zhu Tao, Cheung Joyce C Y, Chen Hexin, Lorincz Annaka, Pandita Raj K, Sharma Girdhar G, Ha Hyo Chol, Gasson Judith, Hanakahi Les A, Pandita Tej K, Sukumar Saraswati
A role for the HOXB7 homeodomain protein in DNA repair
Lill M C, Lynch M, Fraser J K, Chung G Y, Schiller G, Glaspy J A, Souza L, Baldwin G C, Gasson J C
Production of functional myeloid cells from CD34-selected
hematopoietic progenitor cells using a clinically relevant ex vivo
Stem cells (Dayton, Ohio),
Silberstein D S, Owen W F, Gasson J C, DiPersio J F, Golde D W, Bina J C, Soberman R, Austen K F, David J R
Enhancement of human eosinophil cytotoxicity and leukotriene synthesis
by biosynthetic (recombinant) granulocyte-macrophage
Journal of immunology (Baltimore, Md. : 1950),
Gasson J C, Golde D W, Kaufman S E, Westbrook C A, Hewick R M, Kaufman R J, Wong G G, Temple P A, Leary A C, Brown E L
Molecular characterization and expression of the gene encoding human